Digital Commons Network^™

Instructor Evaluation Of Alchemi: An Immersive Serious Game For Teaching Chemistry, Joshua L. Tan, Kyra Shanelle Martinez Velez, Jedrik James Morales Gayamat, Evan Panugot Gerarcas

DLSU Senior High School Research Congress Conference Proceedings

The Philippine science education faces challenges, including low student achievement. This study explored Alchemi, a novel immersive serious game (in the visual novel format), designed to enhance learning in chemistry laboratories. Alchemi integrates Game-Based Learning (GBL) and Strategic Intervention Material (SIM) principles. Six chemistry instructors evaluated Alchemi's effectiveness using the MEEGA+ Game Quality Scale, assessing player experience and usability. Results showed highly positive instructor perceptions of Alchemi's engagement (high median scores for focused attention, challenge, social interaction, confidence, perceived learning), fun (median 4.25), relevance (median 4.75), and satisfaction (median 4.5). Usability aspects (learnability, operability) also scored highly (median 4.5) and …

Evidence-Based Practice Medication Reconciliation Protocol: Process To Increase Adherence To Medication Reconciliation Process, Oksana Bregman

Student Scholarly Projects

Practice Problem: The practice problem for the primary care facility is the inconsistent completion of medication reconciliation (MR) by primary care providers (PCPs), despite attempts by some providers to compare the clinic medication list with the external records and update the electronic health records (EHR). The absence of a standardized evidence-based practice (EBP) MR protocol has resulted in variable practices and increased risk for medication discrepancies during patient encounters.

PICOT: The PICOT question that guided this project was: In primary care providers (P), how does the Evidence-based practice process redesign and workflow optimization protocol (I) compared to current practice (C) …

Parents Engaging In Early Literacy (Peel): Outcomes From A Shared Reading Program Implemented Via Text Messaging, Victoria Henbest, Brenda L. Beverly, Gina M. Mejia

Victoria S. Henbest Publications

Purpose: Investigators delivered an asynchronous parent education for improving early literacy skills of typically developing preschoolers. The home-based shared-book reading program, PEEL, consisted of strategies modeled via videos and sent as text messages.

Method: Twenty parent-child dyads were randomly assigned to one of two 8-week programs targeting evidence-based early literacy strategies. One parent group was taught strategies to support print-related knowledge for learning to read, and the other learned skills to promote vocabulary and story knowledge underlying comprehension.

Results: The asynchronous parent education resulted in more frequent parental use of taught strategies compared to non-taught strategies during …

Don't Panic! Cuny Academic Works And The April Ada Deadline, Jojo Karlin, Jill Cirasella

Publications and Research

These slides equip libraries to advise authors submitting to CUNY Academic Works about document accessibility. Topics will include: How is CUNY Academic Works changing in response to the new ADA rule about the accessibility of web content, which has a compliance deadline of April 24? What are authors being asked to do differently? What tools are available for them to check and improve the accessibility of their submissions? Who is responsible for making our institutional repository more accessible?

As the expectations for institutional repositories change, the presentation aims to help librarians understand what the changes are and what they mean …

Randomized Controlled Trial Outcomes For Homestyles-2, An Online Obesity Prevention Program For Families With Children In Middle Childhood, Carol Byrd-Bredbenner, Angelica A. Pozzoli, Kaitlyn M. Eck, John Worobey, Karla Pagan Shelnutt, Melissa D. Olfert, Virginia Quick

College of Health Professions Faculty Papers

Background: Parents are children’s primary role models, are food and physical activity gatekeepers, and create the home structure/lifestyle environment. Thus, parents strongly influence children’s weight-related behaviors and have the opportunity to cultivate a “culture of health” within the home. Methods: The aim of the HomeStyles-2 (also called HomeStyles-Child) RCT was to determine whether this online, novel, age-appropriate, family intervention enabled and motivated the 131 systematically randomly assigned by computer parents of children in middle childhood (ages 6 to 11) in the experimental condition to shape home environments and healthy weight-related lifestyle practices to be more supportive of optimal health and …

Feeding Negativity On Social Media: How Compensating Customers Creates Vicious Cycles Of Complaint, Yuchi Zhang, Kunpeng Zhang

Marketing

Purpose

The study explores the paradoxical impact of managerial responses to negative comments on social media, revealing how offering compensation inadvertently escalates negativity into a vicious cycle. Through a unique Facebook policy quasi-experiment, we show that apologies, in contrast, effectively neutralize further complaints.

Design/methodology/approach

We utilize interactive data on Facebook to assess how firms' managerial responses to negative comments – particularly responses involving compensation topics – affect the volume and tone of subsequent complaints. Additionally, we use instrumental variables and difference-in-differences (DID) models to account for potential sources of endogeneity.

Findings

The results reveal that managerial response increase both the …

Special Joint Meeting Of The Finance Committee & Audit Subcommittee - Open Session Book 03/24/2026, Uc Law Sf

2026 Board of Directors Agenda and Materials

No abstract provided.

Artificial Intelligence In Mycology: A Systematic Review Of Species Identification, Biotechnological Assessment, And Explainable Deep Learning Methods, Fati̇h Eki̇nci̇, Mehmet Serdar Güzel, Ilgaz Akata

Turkish Journal of Botany

This review offers a comprehensive analysis of the expanding role of artificial intelligence (AI) in mycological research. It highlights how AI supports the identification of fungal taxa at both microscopic and macroscopic levels, facilitates the detection of toxic species, contributes to ecological mapping, aids in discovering new fungal bioproducts, and enhances precision agriculture practices. Advanced techniques such as convolutional neural networks, you only look once, U-shaped network (UNet), and residual network have demonstrated strong performance in classification, segmentation, and object detection tasks. Additionally, explainable AI (XAI) methods like gradient-weighted class activation mapping (Grad-CAM), local interpretable model-agnostic explanations (LIME), and SHapley …

Cover And Contents

Turkish Journal of Botany

No abstract provided.

Icymi (In Case You Missed It): Moody V. Netchoice, Llc And First Amendment Protections For Social Media Platform Expression, Eric T. Kasper

Tulsa Law Review

No abstract provided.

How Does Striving Against Adversity Impact Emotional Well-Being And Cardiovascular Risk In Children?, Brooks B. Gump, Stefanie Pilkay, Xiafei Wang, Sara Vasilenko, Nader H. Attallah-Yunes, Sarah Woolf-King, Stephen Maisto, Edith Chen, Craig K. Ewart

Population Health Research Brief Series

Working hard and persisting through challenges (i.e., striving) are often encouraged for children who face adversity.  But for children facing severe adversity, striving can come with hidden costs. This brief summarizes findings from a study using data from the Environmental Exposures and Child Health Outcomes (EECHO) cohort (N=283, 2013-2017) of children ages 9-11 in Syracuse, NY. The authors find that children facing adversity who strived harder reported lower depression and hostility. However, high-striving high-adversity children also experienced significantly higher blood pressure and enlarged heart chambers than their lower striving peers, both risk factors for future heart disease.

“I’M So Hungry”: Assessing Stem Sensemaking Through Data-Informed Writing, Bailey Nafziger, Alesia Mickle Moldavan, Katie Brkich

Elementary & Special Education: Faculty Publications

To engage elementary learners in the complex task of STEM sensemaking, teachers must entice and inspire learners to ask questions, explore, and communicate their findings. This article shares a 5E/3D lesson designed and taught in our elementary science methods courses to model how preservice teachers can integrate literacy and mathematics into a science investigation for STEM sensemaking. We modified a traditional lesson on bird beak adaptations to have a differentiated, interdisciplinary writing component justified by data. We discuss why data-supported literacy is a non-negotiable in science education reforms and how teachers can differentiate tasks to make scientific writing more approachable …

Professor Reflects On Thoreau In New Ken Burns Documentary, Marisa C. Atkinson

University of Mississippi News

OXFORD, Miss. – A University of Mississippi faculty expert gets to shine in the upcoming "Henry David Thoreau" documentary produced by Ken Burns.

Molecular Characterization Of Humanized Apoe Mouse Models Reveals Source And Genotype Dependent Differences, Na Wang, Gefei Yu, Zhen Wang, Alla Alnobani, Suren Jeevaratnam, Xue Zhang, Meghan Mcreynolds, Yuzhou Chang, Fangfang Qi, William Tauer, Cassandra Rosenberg, Melissa Wren, Tadafumi C Ikezu, Yuka A Martens, Minghui Wang, Bin Zhang, Gregory W Carter, Michael Sasner, David M Holtzman, Junmin Peng, Long-Jun Wu, Takahisa Kanekiyo, Chia-Chen Liu, Guojun Bu

The Brown Foundation: Institute of Molecular Medicine

Background

Humanized APOE targeted-replacement (TR) mice are essential tools for studying apoE isoform effects in Alzheimer’s disease (AD) and other apoE-related disorders. Despite their widespread use, existing APOE mouse models, generated with different gene targeting strategies, have not been directly compared in terms of apoE isoform expression, lipid profiles, and transcriptomic signatures. Such differences could impact how we interpret APOE genotype-related outcomes, as well as related underlying molecular mechanisms.

Methods

We conducted a comprehensive molecular comparison of humanized APOE mouse models from three sources: Taconic Biosciences (TAC), the Cure Alzheimer’s Fund (CAF), and The Jackson Laboratory (JAX). We assessed apoE …

Photoplethysmography For Measuring Cognitive Load In Xr Environments: A Systematic Review, Alya Alshehhi, Qammer H. Abbasi, Rami Ghannam

School of Engineering Technology Faculty Publications

Photoplethysmography (PPG) is a low-cost, low-power biosensing technology with growing applications in education, particularly for monitoring cognitive load in eXtended Reality (XR) learning environments. Measuring cognitive load is critical for preventing overload and optimising immersive learning, yet existing approaches such as self-reports or Electroencephalography (EEG) are often intrusive, costly or impractical for real-time use. This systematic review is the first to synthesize a decade of research (2015–2025) on the use of PPG for cognitive load measurement in XR. Twenty-three studies were identified and analysed according to PRISMA guidelines, with attention to sensor placement, integration with other modalities, research design, and …

Racial And Ethnic Differences In The Clinical Presentation Of Celiac Disease In The United States: A Multi-Institutional Retrospective Analysis, Joy Zhao, John C. Lin, Jason C. Lin, Stephanie M. Moleski

Division of Gastroenterology and Hepatology Faculty Papers

No abstract provided.

The Argus Brings Home Top Awards From College Press Conference, Jeffery Woodard

Press Releases 2020-2029

No abstract provided.

Thalamic Organization Differentially Contributes To Clinical Conditions In Epilepsy, Qirui Zhang, Sam S. Javidi, Ankeeta Ankeeta, Michael R. Sperling, Zhiqiang Zhang, Joseph I. Tracy

Farber Institute for Neuroscience Faculty Papers

BACKGROUND: The thalamus plays an important role in key clinical conditions of focal temporal lobe epilepsy (TLE), but no investigation has examined whether the same thalamic local and connectome properties shape a patient's status across these different conditions.

METHODS: This retrospective longitudinal MRI study used resting-state fMRI and structural imaging to identify whole-brain focal/regional and connectome-level features associated with six binary clinical conditions of TLE (pre/post-surgery, seizure and neurocognitive outcomes, pathology, seizure subtype, and SOZ lateralization) in 91 patients across two centers (age range: 15-65 years) and 85 matched healthy participants (age range: 18-60 years).

RESULTS: Across conditions, relative to …

Logic Model Development Through A Feasibility Rct For A Group-Based Weight Management Programme, Rod Sheaff, Shokraneh Moghadam, Laura Hollands, Lily Hawkins, Dawn Swancutt, Jenny Lloyd, Jonathan Pinkney, Mark Tarrant

School of Psychology

ObjectivesClinical psychology interventions for reducing obesity have developed alongside pharmacological and surgical treatments, but usually as interventions for individual patients. Any healthcare intervention rests on a logic model: assumptions that through specific physical and social mechanisms, it will produce certain intended outcomes, provided that conducive background conditions (‘contexts’) exist. Using evidence from the feasibility trial preceding a full randomised controlled trial (RCT), this paper assesses the empirical validity of the initial logic model of a new group-based weight management intervention: PROGROUP, designed for patients with body mass index (BMI) ≥40 kg/m2 or ≥35 kg/m2 with comorbidities. We aimed to test …

“For Us, Drones Mean Health”: How Medical Drone Delivery Affects Healthcare Outcomes, Accessibility, And Trust In Remote Regions Of Madagascar, Brianne O'Sullivan, Christallin Lydovick Rakotoasy, Lorie Donelle Phd, Rn, Fcan, Nicole Haggerty, Elysée Nouvet

Faculty Publications

Medical drone delivery (MDD), defined as the use of uncrewed aerial vehicles to transport medical products, is an emerging technological innovation responding to persistent health supply chain challenges in rural and low-resource settings. Within sub-Saharan Africa, MDD systems have demonstrated large-scale success in improving key health outcomes, health supply chain efficiency, and reductions in medical product stockouts and wastage. However, the existing evidence base on the effectiveness of this technology is dominated by quantitative, performance-based evaluations, with limited emphasis on the community-driven mechanisms that shape such outcomes. Drawing on original qualitative research, this article presents a qualitative secondary analysis (QSA) …

Synthetic Lethality Between Rb-Loss And E2f3 Inhibition In Small Cell Cancers Targeted By Pyrimidine Synthesis Blockade, Evan R. Abt, Liang Wang, Grigor Varuzhanyan, Jack Freeland, Tian He, Guadalupe M. Peña-Garcia, Lauryn Ruegg, Jami Mclaughlin, Donghui Cheng, Nikolas G. Balanis, Chia-Chun Chen, Yang Xu, Yi Xing, Sanaz Memarzadeh, Caius G. Radu, Thomas G. Graeber, Owen N. Witte

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Small cell carcinoma is a highly lethal cancer variant often found with neuroendocrine (NE) features, as exemplified by small cell lung cancer and small cell NE prostate cancer (SCPC). A genome-wide CRISPR dependency screen using SCPC models generated through human prostate cell transformation identifies a requirement for the transcription factor E2F3. E2F3 dependency is linked to RB inactivation, a near universal occurrence across small cell cancers. The requirement for E2F3 is shared by RB-deficient cells originating from the prostate, lung, and adnexa. In RB-deficient cancer cells, E2F3 inhibition restrains cell cycle progression, proliferation, and tumor growth in vivo. Inhibition of …

Auditing Genai Literature Search Workflows: A Replicable Protocol For Traceable, Accountable Retrieval In Student-Facing Inquiry, Cristo Leon Ph.D., Michelle Kudelka

STEM for Success Resources

Auditing GenAI literature search workflows, this article evaluates whether AI-assisted literature review retrieval is traceable, metadata-accurate, and reproducible under student-facing conditions. Across four systems and two retrieval postures, the study finds that natural-language prompting often produces unstable or unverifiable citation outputs, while Boolean translation improves auditability but not full reproducibility. The article offers a practical framework for accountable AI-assisted literature search, citation verification, DOI traceability, and transparent evidence retrieval.

Cystic Fibrosis And Sickle Cell Disease Associated With Nonadministration Of Vte Prophylaxis In Hospitalized Adults, Kiera Caparon, Matthew J. Lankiewicz, Jessica Crow, Jennifer C. Yui, John Lindsley, Brandyn D. Lau, Michael B. Streiff, Rakhi P. Naik, Sophie Lanzkron, Lydia H. Pecker, Peggy Kraus, Elliott R. Haut, Jiangxia Wang, Kathryn E. Dane

Cardeza Foundation for Hematologic Research

Cystic fibrosis (CF) and sickle cell disease (SCD) are associated with an increased risk of venous thromboembolism (VTE), and this risk is exacerbated by hospitalization. VTE prophylaxis nonadministration is a VTE risk factor. The objective of this study was to characterize VTE prophylaxis nonadministration among patients with either CF or SCD compared with medically ill patients without CF or SCD. We conducted a single-center retrospective cohort study of hospitalized patients who were prescribed at least 2 doses of pharmacologic VTE prophylaxis. The primary outcome was the proportion of nonadministered VTE prophylaxis doses by cohort. Multivariable logistic regression was used to …

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.

Fecal Carbohydrate-Degrading Bacteria Are Associated With Reduced Incidence Of Lower Gastrointestinal Gvhd, Christopher Fan, Tomo Hayase, Chia-Chi Chang, Israel K Glover, Ivonne I Flores, Lauren K Mcdaniel, Miriam R Ortega, Christopher A Sanchez, Rawan K El-Himri, Alexandria N Brown, Jennifer L Karmouch, Mohamed A Jamal, Saira S Ahmed, Taylor M Halsey, Yimei Jin, Wen-Bin Tsai, Rishika Prasad, Altai Enkhbayar, Aqsa Mohammed, Maren Schmiester, Ashish Damania, Nadim J Ajami, Jennifer A Wargo, Christine B Peterson, Gabriela Rondon, Taha Al-Juhaishi, Amin M Alousi, Jeffrey J Molldrem, Richard E Champlin, Elizabeth J Shpall, Eric Martens, Cesar A Arias, Robert R Jenq, Eiko Hayase

Faculty, Staff and Student Publications

Lower gastrointestinal graft-versus-host disease (LGI-GVHD) carries morbidity and mortality for patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT), with critical contributions from the intestinal microbiome. In a retrospective cohort of metagenomic sequencing of stool from patients with allo-HSCT (N = 90), we found that a reduction in specific Parabacteroides and Bacteroides species around the time of engraftment contributes to LGI-GVHD risk. Given the known diverse carbohydrate-degrading functionality of these bacteria, we investigated gene abundances for carbohydrate-active enzymes (CAZymes) and found that Parabacteroides merdae, P distasonis, and Bacteroides ovatus abundances were significantly correlated with CAZymes in patients who did not develop …

Genome-Wide Crispr Screen Identifies A Cytokine-Enhancer Circuit Driving Hif-2Α Activation In Renal Cancer, Jun Fang, Jeremy M Simon, Tao Wang, Yunpeng Gao, Xianju Bi, Lianxin Hu, Chengheng Liao, Cheng Zhang, Yayoi Adachi, Jin Zhou, Hongyi Liu, Qian Liang, James A Nathan, Ram Mani, James Brugarolas, Qing Zhang

Faculty, Staff and Student Publications

Resistance to HIF-2α inhibitors such as Belzutifan underscores the need to better understand how HIF-2α is transcriptionally regulated in clear cell renal cell carcinoma (ccRCC). Here, we uncover a cytokine-driven enhancer mechanism that sustains HIF-2α expression through the JAK1-STAT3 signaling pathway. Using a genome-wide CRISPR screen in VHL-deficient ccRCC cells, we identified SOCS3 as a key negative regulator of HIF-2α. Mechanistically, loss of SOCS3 activates JAK1-STAT3 signaling, leading to the recruitment of STAT3 to distal enhancers upstream of EPAS1 that physically loop to its promoter to drive HIF-2α transcription. This cytokine-enhancer circuit was recapitulated in ccRCC patient samples and functionally …

The Infinite-Decimally Punctured Wave: A Corpuscular Visualization Of Wave-Particle Duality, Florentin Smarandache

Neutrosophic Sets and Systems

No abstract provided.

Integrated Plithogenic Quantum Decision Making On Smart And Sustainable Electrical Material Selection, Nivetha Martin, Davron Aslonqulovich Juraev, Florentin Smarandache, F. X. Edwin Deepak, P. Sathya, Gabriel Xg Yue

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Sets And Systems, Vol. 97,2026, Florentin Smarandache, Mohamed Abdel-Basset, Maikel. Leyva Vazquez

Neutrosophic Sets and Systems

No abstract provided.

A Cross-Sectional Survey On Hpv Vaccination In A Houston Hiv Clinic, Shailee R Modi, Erika S Fanous, Avery N Sinnathamby, Laura O Van Buskirk, Jason L Holliday, J Brooks Jackson, Mary B Rysavy

Faculty, Staff and Student Publications

Background/Objectives: Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide and causes cervical cancer in women. Patients with human immunodeficiency virus (HIV) are particularly susceptible to this virus. An effective vaccine against high-risk HPV genotypes is available. This study sought to evaluate barriers to HPV vaccination in HIV-positive female patients between the ages of 18 and 65 in a county clinic in Houston.

Methods: A cross-sectional survey was conducted in May-June 2025 with 131 patients at Thomas Street Health Center in Houston. The survey assessed patient demographics, attitudes toward and knowledge of HPV vaccination (at least one dose), …