Digital Commons Network^™

Nursing Migration And The Global Workforce: How The U.S. Nurse Shortage Impacts Developing Countries, Mololuwa Faithful Lasekan

Honors Thesis

As United States (U.S.) healthcare organizations face persistent staffing gaps driven by an aging population, burnout, and limited educational capacity, many institutions increasingly rely on internationally educated nurses (IENs) to stabilize their workforce. This reliance intersects with longstanding structural challenges in low- and middle-income countries (LMICs), where inadequate compensation and limited professional opportunities contribute to high migration intentions among nurses. Using a systematic literature review guided by PRISMA principles, this study synthesized evidence and five major themes emerged: (1) push factors driving nurse emigration from LMICs, (2) pull factors attracting nurses to the U.S., (3) digital globalization and post-COVID recruitment …

The Plain Solution To Federal Habeas, Charles Eric Hintz

Utah Law Review

Federal habeas is a mess. The reason is the current doctrine’s myopic proceduralism: its obsession with limiting relief through stringent and Byzantine procedural rules. This has transformed our system of federal postconviction review into an impassible thicket of procedure that forecloses merits review in even strong cases; ensnares everyone in difficult threshold questions; and delays dispositions. Habeas today is thus unfair, opaque, and inefficient, and it fails to promote its own values: fairness, judicial economy, federalism, finality, anti-gamesmanship, and non-technicality. How should we fix this problem? This Article advances a solution based on “plain error” review. Under this approach, habeas’ …

The New Debate Over History: Justice Thomas And Justice Barrett On The Future Of Analogical Reasoning, Jason Buhi

Utah Law Review

The U.S. Supreme Court has entered a new era of debate regarding the appropriate use of history and tradition in constitutional interpretation. Justices Thomas and Barrett established the initial terms of that debate in New York State Rifle & Pistol Association, Inc. v. Bruen (2022), framing the issues as whether courts should interpret individual rights provisions based on their meaning when the Bill of Rights was ratified in 1791 or when the Fourteenth Amendment was adopted in 1868, and what weight post-ratification practice should carry in determining original meaning. The exploration of these issues sparked broader discussions that appear to …

Advancing The Study Of Politics And The Brain: Targets For Research On Neurology And Political Behavior, Glenn W. Rainey Jr.

Commonwealth Review of Political Science

In this paper I argue that advancing research on neurology is creating important opportunities for political scientists to integrate its findings into their research, particularly with regard to the effects of emotional processes on political behavior.  I provide a general background on neural anatomy, genetics, and neurobiological chemicals, and I briefly review techniques of neurological research, the findings that have been developing, and the limitations on the research. I provide an overview of selected key neural anatomy, and neurotransmitters and hormones, that play a role in neurological functions, and particularly in the development and expression of emotions.  I then suggest …

Presidential Search Committee Minutes, Clemson University Board Of Trustees, 2026 April 8, Clemson University Board Of Trustees

Minutes

No abstract provided.

Psychologists’ Preparedness And Self-Efficacy In Serving Grieving Hispanics During Covid-19, Janet Salinas Sanchez

Walden Dissertations and Doctoral Studies

Mental health professionals working with Hispanic populations often face challenges in addressing grief, a culturally multifaceted experience influenced by traditions and familial and community practices. The purpose of this qualitative study was to examine psychologists’ self-efficacy and preparedness in managing grief among Hispanic individuals who have been affected by COVID-19, address cultural factors in grief management, and identify demographic or professional factors that predict higher self-efficacy in working with Hispanic clients. Data were collected at a single point in time from eight psychologists who were actively working or had worked with Hispanic populations during COVID-19 to explore psychologists’ self-efficacy, preparedness, …

From Competition To Complementarity: Narrative Review Of Laser Interstitial Thermal Therapy, Focused Ultrasound, And Radiofrequency Ablation In Minimally Invasive Neurosurgery, Tirath Patel, Hamza Yousuf Ibrahim, Tanzeela Khan, Tehreem Tabrez, Sara Hussain, Alishba Fatima, Aaliya Junaid Siddiqui, Nikhilesh Anand

School of Medicine Publications

Minimally invasive neurosurgical techniques have emerged as a transformative paradigm, offering alternatives to conventional open approaches. The demand for safer, less invasive procedures accelerated the development of laser interstitial thermal therapy (LITT), focused ultrasound (FUS), and radiofrequency ablation (RFA), each employing a distinct mechanism with unique clinical implications. The objective was to critically evaluate and contextualize LITT, FUS, and RFA with emphasis on their comparative efficacy, safety, and roles as competing or complementary technologies in minimally invasive neurosurgery. Literature published between 2005 and 2025 was identified through PubMed, Scopus, and Web of Science, using keywords “LITT,” “FUS,” “RFA,” “minimally invasive …

Multi-Trait Polygenic Scores For Copd And Copd Exacerbations Implicate Druggable Proteins, Chengyue Zhang, Iain R Konigsberg, Yixuan He, Jingzhou Zhang, Tinashe Chikowore, William B Feldman, Xiaowei Hu, Yi Ding, Bogdan Pasaniuc, Diana Chang, Qingwen Chen, Jessica A Lasky-Su, Julian Hecker, Martin D Tobin, Jing Chen, Sean Kalra, Katherine A Pratte, Hae Kyung Im, Emily S Wan, Ani Manichaikul, Edwin K Silverman, Russell P Bowler, Leslie A Lange, Victor E Ortega, Alicia R Martin, Michael H Cho, Matthew R Moll

Faculty, Staff and Student Publications

BACKGROUND

We constructed multi-trait polygenic risk scores (PRSs) predicting chronic obstructive pulmonary disease (COPD) and exacerbations, validated their performance in diverse cohorts, and identified PRS-related proteins for potential therapeutic targeting.

METHODS

PRSmix+, a multi-trait PRS framework, is used to train a composite PRS (PRSmulti) in COPDGene non-Hispanic White participants (n = 6,647). Associations of PRSmulti with COPD status (GOLD 2–4 vs. GOLD 0 or ICD) and exacerbation frequency were tested in COPDGene African American (n = 2,466), ECLIPSE (n = 1,858), Mass General Brigham Biobank (n = 15,152), and All of Us (n = 118,566). …

Hispanic Students As Environmental Scientists: Culturally Sustaining Stem Pathways Through Raíces Y Ciencia, Uma Ganesan

Teaching and Learning Faculty Publications

This study examines how culturally and linguistically sustaining environmental STEM education (CLSE-STEM) fostered student agency and environmental consciousness among Hispanic/Latinx students in Rio Grande Valley border schools. Through qualitative analysis of the Raíces y Ciencia project's water quality investigations, the research explored how teachers integrated students' cultural and linguistic resources with environmental science learning. Data from conference panel presentations, educator surveys, and classroom artifacts revealed three key themes: linguistic border-crossing as scientific understanding pathways, connecting family knowledge to environmental justice advocacy, and positioning students as community researchers. Findings demonstrate that centering Hispanic students' cultural assets while addressing local water quality …

Correction: Exploiting Prmt5 As A Target For Combination Therapy In Mantle Cell Lymphoma Characterized By Frequent Atm And Tp53 Mutations, Yuxuan Che, Yang Liu, Yixin Yao, Holly A Hill, Yijing Li, Qingsong Cai, Fangfang Yan, Preetesh Jain, Wei Wang, Lixin Rui, Michael Wang

Faculty, Staff and Student Publications

No abstract provided.

An Artificial Intelligence Optimized Hepatic Differentiation Unveils Nr5a2 And Ap-1 Transcriptional Regulation In Hepatic Maturation, Zijun Huo, Jian Tu, Wei-Lei Yang, Mo-Fan Huang, Ruoyu Wang, Chih-Wei Chu, An Xu, Yao Yu, Tara N Tavakol, Mikal Kizilbash, Megan E Fisher, Yu-Wen Huang, Dandan Zhu, Trinh T T Phan, Rachel Shoemaker, Ya-Wen Chen, Yang Zhang, Chad D Huff, Shih-Yu Chen, Tien-Jen Liu, Haipeng Xiao, Dung-Fang Lee, Ruiying Zhao

Faculty, Staff and Student Publications

The generation of hepatocyte-like cells (HLCs) from human pluripotent stem cells (hPSCs) holds great promise for drug discovery and cell-based therapy for liver disease. However, current differentiation protocols are complicated and unstable, and the underlying gene regulatory mechanisms of hepatic differentiation remain incompletely defined. Here, we developed a machine learning-based artificial intelligence (AI) tool using phase-contrast images of hepatic progenitor cells (HPCs), which are essential for generating HLCs. The AI tool significantly improves the success rate of hepatic differentiation without the need for immunostaining or lineage tracing. By optimizing the methodology, we achieved an impressive purity of 90-95% for HLCs …

The Effects Of Orexin Receptor Antagonism During Early Withdrawal In Stimulant Use Disorder: Protocol For A Proof-Of-Concept Study, Heather Webber, Nikky Tran, Rita Blake, Sarah Goldman, Trevor George, Bill Bailey, Robert Suchting, Jin Yoon, Jessica Vincent, Michael Weaver, Joy Schmitz, Scott Lane

Faculty, Staff and Student Publications

Background: Stimulant use disorders (StimUDs), including cocaine and methamphetamine use disorders, remain a major public health concern in the United States with no US Food and Drug Administration (FDA)-approved pharmacological treatments. The early recovery period following stimulant use is marked by sleep disturbances, heightened stress reactivity, and dysregulated reward processing, contributing to high rates of resumption of use. Evidence from animal and human studies supports the orexin neuropeptide system as a promising therapeutic target for minimizing these disruptive mechanisms. Suvorexant, an FDA-approved dual orexin receptor antagonist for insomnia, has previously been shown to improve sleep, reduce stress, and attenuate craving …

Newsletter 2026.04.08, Fcrh Honors Program

What's Going On, Honors? (2025-26)

No abstract provided.

The Clinical And Operational Value Of Early Comprehensive Ngs In Non-Small Cell Lung Cancer, Yunus Emre Demirhan, Marcus Yoakam, Adam Soltani, Arshdeep Gill, Samir Dalia

Student Publications

Lung cancer remains the leading cause of cancer-related mortality worldwide, and non-small cell lung cancer (NSCLC) accounts for most cases. Advances in targeted therapies and immunotherapy have improved outcomes, but their benefit depends on timely molecular characterization. Early next-generation sequencing (NGS), performed at or near diagnosis, is increasingly used to identify actionable alterations and inform first-line and perioperative treatment planning. In this review, we examine the clinical, operational, and economic rationale for early comprehensive NGS in NSCLC. Upfront sequencing can improve diagnostic yield, preserve limited tissue, reduce turnaround time, and help avoid non-matched systemic therapy. Practical implementation strategies include Molecular …

Contraception In The Ed: Understanding Education And Opportunities For Clinicians To Advise Patients, Hannah B. Lewis, Teagan R. Mccarthy, Dara Kass, Jennifer L. Kahoud

Department of Emergency Medicine Faculty Papers

Introduction: The United States faces a high rate of unwanted pregnancies. Despite this, many people continue to face barriers to accessing contraception. The emergency department (ED) can help bridge these gaps, but emergency clinicians must first feel comfortable offering contraceptive services. In this study, we sought to determine emergency clinician comfort in prescribing contraceptives and educating patients on their use. We also gauged clinician interest in receiving education specifically geared toward contraceptive care.

Methods: We conducted an online survey of ED residents, attendings, and advanced practice clinicians at Thomas Jefferson Univerity Hospital and affiliates in both the urban and suburban …

What Are The Top 10 Global Research Priorities For Perianal Crohn's Disease? The Global Perianal Crohn's Disease Priority Setting Partnership, Theo Pelly, Parakkal Deepak, Et Al.

2020-Current year OA Pubs

BACKGROUND AND AIMS: Perianal Crohn's disease (pCD) is a debilitating condition with a prevalence of approximately 20% in patients within 10 years of diagnosis of CD. The condition significantly impacts patient quality of life, and there remain a number of unmet needs relating to its optimal management. A global Priority Setting Partnership (PSP) was established to identify the top 10 research priorities for pCD.

METHODS: The PSP followed standard James Lind Alliance (JLA) methodology. An initial survey was circulated to gather unanswered research questions from key stakeholders. From these responses, a longlist of summary questions was formed. These questions were …

Clingen Api Platform For Classification Of Human Genetic Variants, Neethu Shah, Tierra Farris, Arturo Alejandro Zuniga, Andrew R Jackson, Jessie Arce, Kevin Riehle, Christine G Preston, Mark E Mandell, Bryan Wulf, Gloria Cheung, Keyang Yu, Deborah I Ritter, Dubravka Jevtic, Miroslav Milinkov, Novak Martinovic, Nevena Vucinic, Aleksandar Mihajlovic, Alan F Rubin, Melissa S Cline, Marina Distefano, Malachi Griffith, Obi L Griffith, Matt W Wright, Teri E Klein, Sharon E Plon, Aleksandar Milosavljevic

Faculty, Staff and Students Publications

In this commentary, we describe how the Clinical Genome Resource's (ClinGen's) application programming interface-based microservices accelerate growth and dissemination of knowledge about human genetic variation. By exposing findable, accessible, interoperable, reusable, and AI-ready variant data, ClinGen lays a foundation for next-generation software applications, AI systems, and variant classification workflows.

Overlapping Mhc Class I/Ii Epitopes Program Cdc1-Like Differentiation Of Monocyte-Derived Dendritic Cells Via Mtorc1 Signaling Inhibition, S B Amanya, A Murthy, N Bisht, Z N Bullock, K J Ernste, J Vasquez-Perez, W Liu, A Trivedi, D Oyewole-Said, A Paul, L Umokoro, V Akhanov, M Samuel, Z Shi, M H Nguyen, S Huang, M Jeong, P Iakova, K A Jain, K Pham, D C Kraushaar, V Konduri, W K Decker

Faculty, Staff and Students Publications

Viral infection polarizes monocyte-derived dendritic cells (moDC) to initiate type 1 immunity. The availability of overlapping (homologous) MHC class I and II epitopes, an occurrence frequently and primarily associated with intracellular infection, significantly enhances this process; however, the underlying mechanism(s) are unclear. We demonstrate that moDC loaded with homologous MHC epitopes acquire a cDC1-like phenotype in a process governed by mTORC1. mTORC1 pathway inhibition leads to NF-κB-mediated expression of IL-12 and other type I immune polarizing genes. The observed cDC1-like gene signature was also significantly enhanced in clinical moDC vaccine products made through methodologies that enforced class I and II …

Interview No. 1841, Rubén Casas

Combined Interviews

This interview with El Pasoan Rubén Casas reflects on his childhood both in Ciudad Juárez and El Paso, as well as his experiences growing up in Segundo Barrio. Casas describes his early life in Juárez as centered around family, where relatives lived together on his grandmother’s property and spent time together daily. In 1959, when he was around ten or eleven years old, his family moved to El Paso after his mother wanted a different life for the family. The transition was difficult because he struggled to adapt to a new culture, environment, and language. Despite the challenges, he gradually …

Exploring The Landscape Of Indian Library And Information Science Journals: A Bibliometric Perspective On Publication Productivity And Authorship Patterns, Shiva Kumara S U, Sampath Kumar Bt

Library Philosophy and Practice (e-journal)

The present study aims to ascertain the publication productivity, authorship patterns, and the Degree of collaboration in two Indian Library and Information Science (LIS) journals. The related data was extracted from two LIS journals viz., “Annals of Library and Information Studies” (ALIS) and “DESIDOC Journal of Library & Information Technology” (DJLIT). The study findings show that there is a gradual decline in the number of publications published in both journals from 2015 to 2022. It is also noticed that collaborative research is on the rise in LIS literature and two-authored papers are the most common. The average degree of collaboration …

The Density Dilemma: Reconciling Energy Efficiency And Social Well-Being In Compact Housing, Adeb Ebrahim

Architecture and Planning Journal (APJ)

This study examines compact housing not only in terms of urban design. From a sequential exploratory mixed-methods approach study on 120 residential units in Sana’a, we observed that there is a paradox where energy modular housing consumes 28% less energy, but social isolation increases 22%. However, this paradox is countered by the design of biophilic shared spaces (β = -0.34). This research establishes a case for more equitably accessible policies on density and proposes that high-density urban fabrics must have a “social connector” code. This study integrates Fainstein's (2020) concept of the 'just city' and contemporary housing innovations into the …

Exploring Teachers’ Perceptions Of School Counselor-Principal-Teacher Collaboration, Collective Teacher Efficacy, And Leadership, Rachel Louise Geesa, Sherri Barrow, Rochelle Maynard, Derien D. Kunce

Mid-Western Educational Researcher

Efforts to support students' academic, social/emotional, personal, and future professional well-being often rely on the collaboration among educational leaders, educators, and community partners. In this study, we examine teachers' perceptions of collaboration among school counselors, principals, and teachers to enhance school culture, with a focus on collective teacher efficacy. We also provide insights for school leaders (e.g., principals, school counselors, and teachers) to implement systemic changes that promote collaboration and student success. This study is framed through the social cognitive theory, where self-efficacy shapes how educators perceive their ability to impact the learning environment and engage students. Using a mixed-methods …

The Shorthorn: December 4, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: December 5, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: December 3, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: December 2, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 25, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 26, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 21, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.

The Shorthorn: November 20, 1980

The Shorthorn Newspaper Collection: 1980s

No abstract provided.