Digital Commons Network^™

Advancing Cancer Classifcation Through Machine Learning Analysis Of Rna-Seq Gene Expression Data, Emil Agbemade, Amina Issoufou Anaroua, Dimitri Bamba

Data Science and Data Mining

This study delves into the classifcation of various cancer types using the RNA-Seq (HiSeq) PANCAN dataset from the UCI Machine Learning Repository, which encompasses a rich collection of gene expression data across multiple tumor samples. To improve cancer diagnosis and treatment, our methodology confronts the challenges inherent in high-dimensional datasets, such as the Hughes Effect and the Curse of Dimensionality, through innovative feature selection methods and machine learning approaches. A key component of our strategy includes the use of tree-based algorithms, particularly Random Forest, to refine the dataset to seventy genes of utmost relevance for tumor classifcation, and the application …

Predicting Superconducting Critical Temperature Using Regression Analysis, Roland Fiagbe

Data Science and Data Mining

This project estimates a regression model to predict the superconducting critical temperature based on variables extracted from the superconductor’s chemical formula. The regression model along with the stepwise variable selection gives a reasonable and good predictive model with a lower prediction error (MSE). Variables extracted based on atomic radius, valence, atomic mass and thermal conductivity appeared to have the most contribution to the predictive model.

Modeling Health Insurance Premium Using Bayesian Hierarchical Models, Bennedict Kongyir, Emil Agbemade

Data Science and Data Mining

Insurance pricing requires pragmatism and creativity due to the unpredictable nature of risk [3]. This paper explores Bayesian hierarchical models to model health insurance premiums using individual and group predictors like demographics, health status, and geography. Data from Kaggle on health insurance policyholders was utilized, with prior distributions enhanc­ing model interpretability and credibility. Bayesian models improve predictive accuracy and provide valuable insights for actuaries and policymakers, highlighting the signifcant impact of factors such as age and BMI on premium pricing.

Predicting Telecommunication Customer Attrition Using The Hopfeld Neural Network Model., Benedict Kongyir, Emil Agbemade, Kelvin Njuki

Data Science and Data Mining

Customer churn prediction has become one of the crucial steps for customer retention. Telecommunication companies rely on loyal customers to make their proft. It is often very easy for customers to switch from one service provider to the other. To prevent or reduce the rate of customer attrition, there needs to be a model that can identify customers who are at risk of churning in the future in advance. Previous literature has shown that predictive models are efective in predicting customer churn. In this work, four tentative machine-learning models are built using data obtained from Kaggle on telecommunication customer attrition …

Structural Modification Of 4'-Aminochalcones As Α-Glucosidase Inhibitors, Emmanuel Sunday Idoko

Chulalongkorn University Theses and Dissertations (Chula ETD)

Diabetes mellitus, one of the most predominant health problems worldwide, characterized by hyperglycemia, has attracted the attention of medicinal chemists. Although several therapeutic drugs have been developed and used clinically, diabetes continues to pose a growing threat to public health. One of the promising approaches for treating type 2 diabetes involves reducing the rate of carbohydrate hydrolysis by inhibiting the action of α-glucosidase. Over the years, chalcone analogues have been reported for their vast biological properties and as a promising antidiabetic agent. In this research, two series of 4'-aminochalcone derivatives were designed and synthesized as α-glucosidase inhibitors. Twenty-five alkylated 4'-aminochalcone …

Certain Incident Matrices For Lines Intersecting On Plane, Anawin Chongaumklang

Chulalongkorn University Theses and Dissertations (Chula ETD)

This work studies arrangements of lines on the plane, focusing on Fourier’s 17 lines problem, which involves constructing 101 intersection points with 17 lines. We use code notation and incident matrices to classify possible configurations and develop algorithms to determine which codes are drawable. Special attention is given to the role of multiple points and parallel families in these arrangements. Out of 924 possible codes, 658 are confirmed drawable using a combination of theoretical analysis and computer verification. For the remaining cases, new lemmas are proposed to construct additional intersection points. Our findings offer both theoretical insights and practical algorithms …

High Purity Silver Nano- And Micro Particles With Controllable Shapes By Polymeric Stabilizers, Natsuda Muankhajorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

This work presents a rapid, sustainable, and efficient technique for both recovering silver microstructures from spent button batteries and fabricating flexible conductive materials. In the first phase, a green recovery method was developed using H2O2 as a reducing agent to convert silver sources into high-purity silver microstructures. The morphology of the recovered silver was controlled using polymeric stabilizers (PVP and PVA) whose molecular weights significantly influenced particle shape and aggregation. PVP promoted the formation of uniform silver microplates, while PVA yielded isotropic microspheres. The silver microstructures from the spent button batteries were converted into highly pure silver microstructures (>98%), …

Juvenile Dungeness Face High Predation Risk From Green Crabs Across Increased Temperatures At Different Salinities, Trever Gelling

Environmental Science and Management Undergraduate Departmental Honors Theses

Marine heatwaves, altered precipitation regimes, and other changing climate conditions are altering the abiotic conditions of Oregon's estuaries. Furthermore, warmer water temperatures are correlated with the range expansion and population growth of the invasive and broadly tolerant Carcinus maenas, the green crab, in Oregon. Metacarcinus magister, Dungeness crab, one of Oregon’s most valuable fishery species, is also facing these climate stressors, and their young that recruit to estuaries overlap with C. maenas adults. Therefore, we wanted to determine impacts of C. maenas on young-of-the-year (YOTY) M. magister and the roles of salinity, temperature, and predator size in mediating …

Breathe, Renee J Flores

Faculty and Staff Publications

This is a personal essay about breasts. It focuses on my experiences as a young girl, moving through adolescence to a history of breast cancer in my family, including my mother's breast cancer diagnosis. As a physician, patient, and wife, I reflect on the choices that I have to make and what this means for my identity as a woman and mother.

The D.C. Circuit As A Conseil D'Etat, Andrew Hammond

Articles by Maurer Faculty

A storm is brewing in American administrative law. More and more federal judges, including a majority of the Justices of the Supreme Court, openly question longstanding doctrine. A throng of academics profess skepticism of the same. This formalist turn among judges, lawyers, and academics challenges the very legitimacy of the administrative state. But what does this tempest portend for the D.C. Circuit?

The D.C. Circuit is often described as the nation’s second highest court, but its precise role in the federal judiciary is only fifty years old. As a member of that appellate court, now-Chief Justice John Roberts once admitted …

Translational Neuroscience Contributes To Understanding Neurodevelopmental Outcomes Of Dostoyevsky's "Brothers Karamazov" With Treatment Implications, Stephen I. Deutsch, Jessica A. Burket, Jeffrey Elikan Jd, David R. Spiegel

Department Psychiatry & Behavioral Science Faculty Publications

Dostoyevsky's novels raise profound ethical, moral, philosophical and theological issues and, as a result, both he and his novels serve as fertile subjects of scholarly inquiry across a variety of academic disciplines. In particular, major characters in "The Brothers Karamazov" lend themselves to classical psychodynamic formulations, such as the influence of adverse childhood experiences on adult social and occupational outcomes, which in the case of Dmitry, the eldest son of Fyodor Pavlovich Karamazov, are considered in exquisitely fine detail. Prosecutor and defense attorney provide differing interpretations of how early traumas, largely due to paternal neglect and abuse, affected Dmitry's adult …

Colby College Catalogue 2024–2025, Colby College

Colby Catalogues

No abstract provided.

Institutional Antiracism And Critical Pedagogy: A Quantum Leap Forward For Legal Education And The Legal Academy, Danielle M. Conway

Faculty Scholarly Works

A fundamental launchpad for redeeming American society is to look to the historical and contextual goals of the Second Founding—the Reconstruction Amendments—and grasp the lessons about justice and equality for all by focusing on the principles of institutional antiracism. While our nation should deploy teaching and learning strategies at all levels of the American system of education, legal education must be out front leading the way to incorporate institutional antiracism through critical pedagogy.

This article provides the historical context in which legal education developed in the antebellum and postbellum periods and up to what might be deemed the “Third Founding” …

Tumefactive Demyelinating Lesions: A Literature Review Of Recent Findings, Yaser M. Al Malik

Neurosciences

Tumefactive demyelinating lesion is a variant of multiple sclerosis that is a diagnostic challenge. Tumefactive demyelinating lesion requires extensive work-up as its clinical and radiological features are often indistinguishable from other central nervous system lesions, such as tumors. Diagnosis is further complicated by the increasing recognition that tumefactive demyelinating lesions can occur alongside, evolve into, or develop from numerous conditions other than multiple sclerosis, pointing to a possible overlapping etiology. We review herein relevant studies from 2017 onwards to provide a current view on the pathogenesis, clinical and imaging findings, novel diagnostic techniques for differential diagnoses, and management of tumefactive …

Intracerebral Benign Fibrous Histiocytoma, Liusong Yang, Mingzhe Zheng, Yingfeng Zhu, Zhongqing Chen

Neurosciences

Benign fibrous histiocytoma (BFH) within the intracerebral region is remarkably rare. Our report details 2 cases of unusual BFH instances that exhibit no adhesion to the dura mater or cerebral falx, accompanied by a comprehensive literature review. While magnetic resonance imaging demonstrates specific characteristics for BFH, it does not readily differentiate BFH from more common brain neoplasms like gliomas and metastatic tumors. The definitive diagnosis of BFH depends primarily on histopathological and immunohistochemical examinations. Total surgical resection is considered an efficacious therapeutic approach, emphasizing the necessity for prolonged postoperative surveillance to detect any potential tumor recurrence or metastasis.

“Criminalizing” Depositions In Arbitration, Mitch Zamoff

Articles

Civil litigation–style deposition practice is preventing commercial arbitration from reaching its full potential as an economical, efficient alternative to a civil lawsuit. Although there is consensus among alternative dispute resolution experts that meaningful limits must be imposed on arbitration discovery to unlock the efficiency benefits of arbitration, depositions continue to feature prominently in commercial arbitrations for at least three reasons. First, civil litigators are addicted to depositions. They reflexively propose overdone deposition practice in arbitrations that replicates their litigation experience. Second, arbitrators may hesitate to disallow deposition discovery out of fear that their awards will be vacated for failure to …

Destruction, Proportionality, And Sustainability: A Law-And-Economics Analysis, Thomas F. Cotter

Articles

This Paper undertakes a law-and-economics analysis of the remedy of destruction (and, subsidiarily, the related remedies of recall and removal) of products that infringe intellectual property (IP) rights. We begin with a brief survey of international, regional, and domestic law and practice, observing that (1) courts generally are believed to be more likely to order the destruction of copyright- and trademark-infringing goods than of patent-infringing goods, and (2) the frequency with which courts order the destruction of patent-infringing goods varies from one country to another. Our observations lead us to present two principal theses.

The first is that a comparative …

Shareholders All The Way Down: Eu Corporate Sustainability Reforms And The Structure Of Corporate Governance, Matthew Bodie

Articles

The laws and norms of corporate law are changing across the globe. Gone are the days when scholars could confidently predict that shareholder wealth maximization would be the universal metric of corporate success. Instead, corporate leaders, governments, workers, activists, and even shareholders are looking beyond simplistic models of shareholder primacy to a broader understanding of corporate responsibility. This new approach has taken its firmest hold in the European Union, where three directives over the last decade have reshaped reporting requirements and directors’ duties in significant ways, pushing for greater accountability and attention to the needs of stakeholders.

Changes to company …

Expert Stakeholder Perspectives On Emerging Technology For Neuroimaging Research With Highly Portable Mri: The Need For Guidance On Ethical, Legal, And Societal Issues, Molly K. Madzelan, Frances Lawrenz, Susan Wolf, Francis X. Shen

Articles

Portable MRI (pMRI) technology, which promises to transform brain imaging research by facilitating scanning in new geographic areas and the participation of new, diverse populations, raises many ethical, legal, and societal issues (ELSI). To understand this emerging pMRI ELSI landscape, we surveyed expert stakeholder views on ELSI challenges and solutions associated with pMRI research.

Scientists' Perspectives On Ethical Issues In Research With Emerging Portable Neuroimaging Technology: The Need For Guidance On Ethical, Legal, And Societal Implications (Elsi), Frances Daniels, Efrain Torres, Frances Lawrenz, Susan M. Wolf, Francis X. Shen

Articles

Deployment of new, more portable, and less costly neuroimaging technologies such as portable magnetoencephalography, electroencephalography, positron emission tomography, functional near-infrared spectroscopy, high-density diffuse optical tomography, and magnetic resonance imaging is advancing rapidly. Given this trajectory toward increasing use of neuroimaging outside the hospital, we sought to identify ethical, legal, and societal implications (ELSI) of these new technologies by understanding the perspectives of those scientists and engineers developing and implementing portable neuroimaging technologies in the United States, Europe, and Asia. Based on a literature review, we identified and contacted 19 potential interviewees and then conducted 11 semi-structured interviews in English by …

Advancing Global Equity And Justice Through Evidence And Innovation—Annual Report 2022–2023, Population Council

Annual Reports

No abstract provided.

Support For Healthcare Provider Education—Overview, Ipm South Africa

Dapivirine Vaginal Ring (PrEP Ring)

This document provides an overview of the Population Council’s Healthcare Provider (HCP) education resources to support healthcare providers and other key stakeholders to raise awareness for, prescribe and support women to use of the dapivirine vaginal ring (DVR, also known as the PrEP ring).

“Your Legs Don’T Look All That Good” An Analysis Of Impoliteness And Politeness In Individuals With Traumatic Brain Injuries In The Workplace, Grace Kozal

Theses and Dissertations--Communication Sciences and Disorders

Background: Social communication disorders are a common outcome from traumatic brain injury (TBI). This social communication disorder can be seen through impolite speech acts during conversation. While politeness is a social norm for workplace discourse, instances of impoliteness may have poor consequences. This research explores the use of impoliteness in persons with TBI within computer generated work-based conditions.

Methods: Language samples from the Voicemail Elicitation Task (VET) and Feedback/Advice Spoken Task (FAST) were transcribed word-for-word. Transcripts from all 62 participants were coded for impoliteness using a developed Impoliteness Codebook and were analyzed to identify significant differences in the number of …

Feeding Systems And Fresh Lamb Color Stability, Koushik Mondal

Theses and Dissertations--Animal and Food Sciences

Consumers consider the surface color of fresh lamb as the indicator of freshness and wholesomeness, which affects their purchase decisions. The redox chemistry of myoglobin (Mb) determines the color of fresh lamb. Artificial raising on milk replacer (a pre-weaning strategy) as well as red clover supplementation are management strategies used in lamb production. This thesis focuses on the effects of artificial raising on milk replacer and red clover supplementation on the color and oxidative stability of fresh lamb.

In the first experiment, the effect of pre-weaning with milk replacer on the carcass attributes, color stability and lipid oxidation of lamb …

Knowledge, Experiences, And Perceptions Of Medications For Opioid Use Disorder Among Black Kentuckians, Paris B. Wheeler, Brittany Miller-Roenigk, Jasmine Jester, Danelle Stevens-Watkins

Educational, School, and Counseling Psychology Faculty Publications

Background: Opioid overdoses have continued to increase at higher rates among Black Americans compared to people from other racial groups. Despite demonstrated effectiveness of MOUD in reducing risk of opioid overdose, Black Americans face decreased access to and uptake of MOUD. the current study aimed to examine the knowledge, perceptions, and experiences with MOUD among a sample of Black adults who use prescription opioids nonmedically in order to inform tailored efforts to improve MOUD uptake.

Methods: Data were derived from a larger study assessing cultural and structural influences on drug use and drug treatment among people who use prescription opioids …

Effect Of Video Modeling And Teacher Praise On Turn-Taking Behavior Of Preschoolers In An Inclusive Setting, Happiness Efeturi

Theses and Dissertations--Early Childhood, Special Education, and Counselor Education

This study investigates the efficacy of video modeling combined with teacher praise in fostering turn-taking skills among preschoolers in inclusive settings. Employing a multiple probe across participants design, three preschoolers will undergo baseline, intervention, and maintenance phases. Video modeling sessions, featuring peers engaging in turn-taking activities, will be alternated with teacher praise. Data collected through event recording and analyzed via Microsoft Excel will determine the intervention's impact on turn-taking behavior. Results aim to contribute to literature on effective interventions for preschoolers, offering insights into employing video modeling and teacher praise in inclusive educational environments.

On The Importance Of Listening To Crime Victims . . . Merciful And Otherwise, Paul Cassell

Utah Law Faculty Scholarship

What role should mercy play in the criminal justice system? While several of the other symposium’s articles here in the Texas Law Review argue for expanding mercy’s role, I write to raise a cautionary note. Expanding mercy could potentially conflict with another important feature of contemporary criminal justice: the expanding role of crime victims. Because considerations of mercy focus exclusively on the offender, greater attention to mercy necessarily means less attention to victims. This change in focus would be at odds with a broadly advancing crime victims’ movement in this country and, indeed, in many countries around the world. This …

Restructuring Undefined Assets: Valuation Of Stablecoins And Their Impact On The Bankruptcy Process, Olivia Woodmansee

American University Business Law Review

Difficulties with defining cryptocurrency have plagued federal agencies and courts since crypto’s creation. With the emergence of “crypto winter” in 2022 that saw many crypto-related ventures fail, bankruptcy courts have been challenged to address numerous novel legal issues surrounding crypto-assets. When looking to the Bankruptcy Code fails to provide answers, courts must look to definitions, agency regulations, and an analysis of cryptocurrency’s position in the market to determine its classification. This can quickly become muddled with the voluminous and seemingly conflicting sources that exist. One such issue emerges when courts attempt to determine how to classify a particular cryptocurrency: is …

Ogletree V. Cleveland State University: Orwellian Exam Software’S Erosion Of Fourth Amendment Protections, Robert Leander

UIC Law Review

No abstract provided.

Advanced Practice Nurse Liability In The Age Of Increased Independence, Jesse Klein

UIC Law Review

No abstract provided.