Digital Commons Network^™

Surface And Bulk Properties Of Multi-Component Metal Alloys, Frank A. Mckay Iii

LSU Doctoral Dissertations

While HEAs have been studied extensively for their material properties, their potential as catalysts remains widely unexplored. To explore the feasibility of CoCrFeNi as a catalyst for the hydrogen evolution reaction, the results of X-ray photoelectron spectroscopy (XPS) and high-resolution electron energy loss spectroscopy (HREELS) experiments are compared to electrochemical experiments and theoretical calculations. XPS shows that this surface forms passive oxides with a propensity of Cr > Fe > Co, with no evidence of Ni oxidation. From comparison to calculations, it is shown that the electrochemical activity is enhanced in a partially oxidized state. The lack of Ni oxidation suggests that …

Germline Structural Variation Globally Impacts The Cancer Transcriptome Including Disease-Relevant Genes, Fengju Chen, Yiqun Zhang, Fritz J Sedlazeck, Chad J Creighton

Faculty, Staff and Students Publications

Germline variation and somatic alterations contribute to the molecular profile of cancers. We combine RNA with whole genome sequencing across 1,218 cancer patients to determine the extent germline structural variants (SVs) impact expression of nearby genes. For hundreds of genes, recurrent and common germline SV breakpoints within 100 kb associate with increased or decreased expression in tumors spanning various tissues of origin. A significant fraction of germline SV expression associations involves duplication of intergenic enhancers or 3' UTR disruption. Genes altered by both somatic and germline SVs include ATRX and CEBPA. Genes essential in cancer cell lines include BARD1 and …

Network Of Epistatic Interactions In An Enzyme Active Site Revealed By Large-Scale Deep Mutational Scanning, Allison Judge, Banumathi Sankaran, Liya Hu, Murugesan Palaniappan, André Birgy, B V Venkataram Prasad, Timothy Palzkill

Faculty, Staff and Students Publications

Cooperative interactions between amino acids are critical for protein function. A genetic reflection of cooperativity is epistasis, which is when a change in the amino acid at one position changes the sequence requirements at another position. To assess epistasis within an enzyme active site, we utilized CTX-M β-lactamase as a model system. CTX-M hydrolyzes β-lactam antibiotics to provide antibiotic resistance, allowing a simple functional selection for rapid sorting of modified enzymes. We created all pairwise mutations across 17 active site positions in the β-lactamase enzyme and quantitated the function of variants against two β-lactam antibiotics using next-generation sequencing. Context-dependent sequence …

Synthetic Pet From Ct Improves Diagnosis And Prognosis For Lung Cancer: Proof Of Concept, Morteza Salehjahromi, Tatiana V Karpinets, Sheeba J Sujit, Mohamed Qayati, Pingjun Chen, Muhammad Aminu, Maliazurina B Saad, Rukhmini Bandyopadhyay, Lingzhi Hong, Ajay Sheshadri, Julie Lin, Mara B Antonoff, Boris Sepesi, Edwin J Ostrin, Iakovos Toumazis, Peng Huang, Chao Cheng, Tina Cascone, Natalie I Vokes, Carmen Behrens, Jeffrey H Siewerdsen, John D Hazle, Joe Y Chang, Jianhua Zhang, Yang Lu, Myrna C B Godoy, Caroline Chung, David Jaffray, Ignacio Wistuba, J Jack Lee, Ara A Vaporciyan, Don L Gibbons, Gregory Gladish, John V Heymach, Carol C Wu, Jianjun Zhang, Jia Wu

Faculty, Staff and Student Publications

[18F]Fluorodeoxyglucose positron emission tomography (FDG-PET) and computed tomography (CT) are indispensable components in modern medicine. Although PET can provide additional diagnostic value, it is costly and not universally accessible, particularly in low-income countries. To bridge this gap, we have developed a conditional generative adversarial network pipeline that can produce FDG-PET from diagnostic CT scans based on multi-center multi-modal lung cancer datasets (n = 1,478). Synthetic PET images are validated across imaging, biological, and clinical aspects. Radiologists confirm comparable imaging quality and tumor contrast between synthetic and actual PET scans. Radiogenomics analysis further proves that the dysregulated cancer hallmark pathways of …

Prediction Of 3-Dimensional Coverage Surface Area Of The Femoral Head In Hip Dysplasia Through Conventional Computed Tomography, Tomoyuki Kamenaga, Lucas Ritacco, Pablo A Slullitel, Chadi Nahal, Jeffrey J Nepple, John C Clohisy, Cecilia Pascual-Garrido

2020-Current year OA Pubs

BACKGROUND: Assessment of 3-dimensional (3D) femoral head coverage is critical in evaluating, preoperative planning, and treating hip dysplasia.

PURPOSE: To (1) propose a mathematical model to establish 3D femoral head coverage using conventional computed tomography (CT), (2) determine the correlation of 2D parameters with 3D coverage, and (3) characterize the patterns of dysplasia based on 3D morphology.

STUDY DESIGN: Cross-sectional study; Level of evidence, 3.

METHODS: We identified 30 patients (n = hips) with symptomatic dysplasia and 30 patients (n = hips) without dysplasia. Patients with dysplastic hips were matched with regard to sex, age, and body mass index to …

Predation Without Direction Selectivity, Jenna Krizan, Xiayingfang Song, Michael J Fitzpatrick, Ning Shen, Florentina Soto, Daniel Kerschensteiner

2020-Current year OA Pubs

Across the animal kingdom, visual predation relies on motion-sensing neurons in the superior colliculus (SC) and its orthologs. These neurons exhibit complex stimulus preferences, including direction selectivity, which is thought to be critical for tracking the unpredictable escape routes of prey. The source of direction selectivity in the SC is contested, and its contributions to predation have not been tested experimentally. Here, we use type-specific cell removal to show that narrow-field (NF) neurons in the mouse SC guide predation. In vivo recordings demonstrate that direction-selective responses of NF cells are independent of recently reported stimulus-edge effects. Monosynaptic retrograde tracing reveals …

Full Issue

The Thetean: A Student Journal for Scholarly Historical Writing

No abstract provided.

A Method To The Madness Iraqi Strategy And Diplomacy In The Persian Gulfwar, James D. Smith

The Thetean: A Student Journal for Scholarly Historical Writing

Most Americans are familiar with the essentials of the Persian Gulf War: Iraq invaded Kuwait, triggering a massive buildup of American troops in Saudi Arabia. These troops eventually invaded Kuwait and drove out the Iraqis, who fled in terror before the American juggernaut. Beyond this, few Americans know much. The war is, perhaps, too recent to have developed the wide interest that currently exists in older conflicts such as the Civil War or World War II; the textbook-worthy strategies employed by General Norman Schwartzkopf's forces therefore go largely unnoticed by the public at large.

Search And Destroy: The U.S. Military's Contribution To The Victory Of The North Vietnamese Army, Mike Baer

The Thetean: A Student Journal for Scholarly Historical Writing

On August 7, 1964 both houses of Congress approved the Gulf of Tonkin Resolution, placing congressional support behind the president in repelling "any armed attack against the forces of the United States." The president was also empowered to take, upon request from any nation in Southeast Asia, "all necessary steps, including the use of armed force, to assist {that nation} in the defense of its freedom." This allowed the U.S. to circumvent the Geneva Accords of 1954, which had severely limited the U.S. troop contingent in South Vietnam and prevented any offensive military campaigns. Less than a year after passage …

Corporate Rivalry In The Rocky Mountains: The Hudson's Bay Company's Involvement In The American Fur Trade Rendezvous System, Dale Topham

The Thetean: A Student Journal for Scholarly Historical Writing

In 1825 Wtlliam H. Ashley, co-owner of the Ashley-Henry Fur Company operating out of St. Louis Missouri, instituted the annual rendezvous system. The rendezvous, a summertime gathering of fur trappers, allowed Ashley's employees to remain in the West year-round to trap beaver. A yearly caravan brought supplies out from St. Louis to the rendezvous, where trappers sold their year's catch of beaver and purchased supplies for the oncoming season. Lasting through the summer of 1840, this system of resupplying trappers attracted a variety of people to the rendezvous sites, including Native-Americans, Protestant missionaries traveling to Oregon, adventurers from Europe, and …

Gail And His Snails, Brenden Kimpe

Floodwall Magazine

No abstract provided.

Foraging Behaviour Of Heifers, Sheep And Goats In Grass-Legume Cafeteria, J P. Singh, Vinod Shankar, V S. Upadhyay

IGC Proceedings (1977-2023)

The paper reports findings of a grazing trial with heifers, sheep and goats in a grass–legume cafeteria involving 45x10 m alternate strips of 18 grasses and 18 legumes. In the first year heifers were grazed. Sheep were introduced in the second year and goats in the third year. The stocking rate was 1.5 ACU/ha. Foraging behaviour of three kinds of animals differed in many respects with grazing and rest durations, choice of species in the forenoon and afternoon and in different seasons. Heifers, by and large, preferred grasses over legumes and browse. Sheep, on the contrary, preferred legumes over grasses …

Intake And Diet Selection By Sheep Grazing Grass/Clover Patches, I J. Gordon, A W. Illius

IGC Proceedings (1977-2023)

The effects of the spatial dispersion of ryegrass (Lolium perenne L) and clover (Trifolium repens L), at the feeding station scale, on diet composition and feeding behaviour were studied for sheep. There were no significant changes in diet composition with changes in the spatial dispersion of sward components. Bite size, bite rate and intake rate did increase as the species became more aggregated.

A Quantitative Analysis Of Conscious Capitalism Effects On Gross Profit Margin Over Time, Alyssa Newsom, Arlene Ramkissoon, Douglas Ruml, Edward Lukco

Journal of the North American Management Society

Business is a vital part of American society, and the decisions made by businesses affect more than just the economy. Conscious Capitalism (CC) recognizes this important role, and it challenges businesses to operate in a responsible manner. CC recognizes the need to make a profit in order to succeed in a competitive market, and seeks to encourage profit by following four tenets of conscious business—conscious leadership, conscious culture, stakeholder orientation, and higher purpose— so that businesses attract customers and will experience increased profits over time. This study found that, while the gross profit margins of companies who practice CC were …

Don't Panic! Chatgpt Doesn't Have All The Answers., Elizabeth Tate, Will Phillips, Shawn Keough

Journal of the North American Management Society

This theoretical paper aims to examine the potential benefits and harms of using ChatGPT, a large language model, in post-pandemic higher education institutions. Specifically, we explore how ChatGPT can assist educators in creating more interactive and personalized learning experiences for students. Additionally, we consider the potential negative effects of relying too heavily on ChatGPT. Furthermore, we address the ethical concerns raised by using ChatGPT in the classroom, such as issues of privacy and bias. Overall, this theoretical paper provides an analysis of the use of ChatGPT for promoting quality education in a post-COVID world.

Clinical And Procedural Characteristics Of Successful Transcatheter Device Closure Of Ostium Secundum Atrial Septal Defect In Symptomatic Children Weighing Less Than 15 Kg: A Retrospective Study Spanning One Decade From South India, Shobhit Priyanshu Joseph, Mirza Shohiab Ur Riyaz, Jesu Krupa, Shruti Irene Varghese, Gayathri Bhuvaneswaran Kartha, Oommen K. George, Paul V. George, John Jose, Viji Samuel Thomson

Journal of the Saudi Heart Association

Objectives: This retrospective study sought to determine the feasibility of transcatheter atrial septal defect device closure in patients less than 15 kg, as well as to assess complication rates and the reasons for unsuccessful device closure.

Background: In general, the risks associated with transcatheter atrial septal defect device closure are believed and reported to be relatively low, but the evidence stems from trials involving adults and older children. Current guidelines do not recommend atrial defect closure in device closure in children < 15kg, due to limited data available for feasibility and safety of device closure in this group of patients.

Methods: Retrospective review of all patients who underwent elective transcatheter closure of ostium secundum atrial septal defect between September …

Deficit-Oriented Language Use: Understanding The Effects Of Deficit-Oriented Labeling On First-Generation Students, Jeff Foulkes, Jeff Foulkes

Dissertations

Purpose: The purpose of this sequential mixed methods study was to describe how first- generation undergraduate college students perceive that deficit-oriented and strengths- based language has impacted them during their first year of study. A further purpose of this study was to identify how these students overcome the negative influences that are associated with deficit-oriented language.

Methodology: A sequential mixed methods research design was chosen to address the research questions for this study. Using a convenience sampling approach, the survey was disseminated to all first-year students in a specific program at a single university. Once the quantitative survey data were …

A Multi-Omics Investigation Into The Mechanism Of Action Of An Anti-Tubercular Fatty Acid Analog, Isin T. Sakallioglu, Amith S. Maroli, Aline De Lima Leite, Darrell D. Marshall, Boone W. Evans, Denise K. Zinniel, Patrick H. Dussault, Raul G. Barletta, Robert Powers

Patrick Dussault Publications

The mechanism of action (MoA) of a clickable fatty acid analogue 8-(2-Cyclobuten-1-yl)octanoic acid (DA-CB) has been investigated for the first time. Proteomics, metabolomics, and lipidomics were combined with a network analysis to investigate the MoA of DA-CB against Mycobacterium smegmatis (Msm). The metabolomics results showed that DA-CB has a general MoA related to that of ethionamide, a mycolic acid inhibitor that targets enoyl-ACP reductase (InhA), but DA-CB likely inhibits a step downstream from InhA. Our combined multi-omics approach showed that DA-CB appears to disrupt the pathway leading to the biosynthesis of mycolic acids, an essential mycobacterial fatty acid …

Combining Multi-View Uav Photogrammetry, Thermal Imaging, And Computer Vision Can Derive Cost-Effective Ecological Indicators For Habitat Assessment, Qiao Hu, Ligang Zhang, Jeff Drahota, Wayne Woldt, Dana Varner, Andy Bishop, Ted Lagrange, Christopher M. U. Neale, Zhenghong Tang

School of Natural Resources: Faculty Publications

Recent developments in Unmanned Aircraft Vehicles (UAVs), thermal imaging, and Automachine learning (AutoML) have shown high potential for precise wildlife surveys but have rarely been studied for habitat assessment. Here, we propose a framework that leverages these advanced techniques to achieve cost-effective habitat quality assessment from the perspective of actual wildlife community usage. The framework exploits vision intelligence hidden in the UAV thermal images and AutoML methods to achieve cost-effective wildlife distribution mapping, and then derives wildlife use indicators to imply habitat quality variance. We conducted UAV-based thermal wildlife surveys at three wetlands in the Rainwater Basin, Nebraska. Experiments were …

Faculty Senate Executive Committee Agenda March 18, 2024, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• 3:30 Call to Order
• 3:35 University Business
• 3:55 Faculty Senate Business
• 4:10 Information
• Education Policies Committee
• Presidential Investiture
• Limited English Proficiency (LEP)
• 4:20 Reports
• 4:20 Old Business
• 4:25 New Business
• Administrator Evaluation Discussion
• Faculty Code 409 & 410
• Faculty Senate President Elect
• Adjourn: 5:00 pm

Standardized Patient Overlays In Undergraduate Nursing Simulation To Improve Clinical Competency, Vivian Bowman

SACAD: Scholarly Activities

Nurse educators use simulation as a tool to teach and evaluate clinical skills. The opportunities have expanded with the advancement of new technologies related to high-fidelity (HFS) simulation. However, HFS has limitations, as there is a lack of meaningful two-way communication. During the last 10 years, educators have increased the usage of standardized patients (SPs) in simulation experiences. SPs can add realism to a simulation, providing nonverbal cues and psychological responses that a manikin cannot produce. Hybrid simulation further enhances the SP experience by incorporating a wearable overlay, such as a tracheostomy, urinary catheterization, or chest tube care simulator. This …

2024 March 18 - Faculty Senate Agenda And Minutes, Faculty Senate, East Tennessee State University

Faculty Senate Agendas and Minutes

No abstract provided.

Historical Analogy And The Role Morality Of Reason-Giving, Darrell A. H. Miller

Duke Law Journal Online

The Supreme Court has turned ever more to analogical reasoning from history and tradition to decide significant matters of public policy. Nowhere is this phenomenon more evident than in the Court’s 2022 decision in New York State Rifle and Pistol Association v. Bruen.

The Court’s crafting of a Second Amendment test that turns almost entirely on the strength of analogies—and on a topic of such intense public salience—has thrust analogical reasoning to the forefront of judicial and academic debate. While many have questioned the workability of Bruen’s focus on historical analogs, this Essay is less concerned about the pragmatics of …

The Utah Statesman, March 18, 2024, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Optimizing "Open Data Jawa Tengah" Through Technology Acceptance Model (Tam), Yasykur Hisyam Muáafii False, Priyanto Priyanto False

Elinvo (Electronics, Informatics, and Vocational Education)

The Central Java Provincial Government has implemented the “Open Data Jateng” system since 2019 for public services. Open Data is part of the application of big data, and the system does not yet have evidence to meet data needs. So, an explanatory method of research was conducted using a prediction study. The research variables are based on the development of the Technology Acceptance Model (TAM) theory and the 3Q model theory. 130 respondents from the exKaresidenan of Semarang City filled out 21 statements, then tested through Partial Least Square - Structural Equation Modeling (PLSSEM). The result is that there is …

Coping With California’S Deficit, Part 1: Borrowing And Taxes, David Gamage, Darien Shanske

Faculty Publications

In this installment of Academic Perspectives on SALT, Shanske and Gamage examine California’s projected budget deficit and possible solutions. California has a large budget deficit that is predicted to last for several years. In this two-part series, we will place California’s situation in context and propose solutions.

The state should use short-term borrowing to cover at least some of the cyclical shortfall. That the real revenue cycle is unlikely to neatly unfold over one traditional fiscal year should not change this conclusion. To that end, we will show how California can operationalize this simple insight despite the impression some may …

Point Of View On Outcome Prediction Models In Post-Stroke Motor Recovery, Onno Van Der Groen, Manonita Ghosh, Richard Norman, Amy Kuceyeski, Ceren Tozlu, Teresa J. Kimberley, David J. Lin, Laurel J. Buxbaum, Gert Kwakkel, Steven C. Cramer, Dylan J. Edwards

Moss-Magee Rehabilitation Papers

Stroke is a leading cause of disability worldwide which can cause significant and persistent upper limb (UL) impairment. It is difficult to predict UL motor recovery after stroke and to forecast the expected outcomes of rehabilitation interventions during the acute and subacute phases when using clinical data alone. Accurate prediction of response to treatment could allow for more timely and targeted interventions, thereby improving recovery, resource allocation, and reducing the economic impact of post-stroke disability. Initial motor impairment is currently the strongest predictor of post-stroke motor recovery. Despite significant progress, current prediction models could be refined with additional predictors, and …

March 18 Roundtable Update, Jeffrey M. Wice

Elections, Census & Redistricting Updates

No abstract provided.

Prediction Method Of Surrounding Rock Deformation Of Highway Tunnels Based On Bayes‑Lstm, Liu Zhi, Li Xinyu, Li Zhen, Kong Xianguang, Chang Jiantao

Journal of China & Foreign Highway

In the process of highway tunnel construction，the stability of surrounding rock has a great impact on tunnel construction.Therefore，the monitoring measurement and accurate prediction of surrounding rock deformation of highway tunnels are the keys to ensuring the safety of tunnel construction.In view of the low prediction accuracy and poor generalization ability of tunnel surrounding rock deformation，this paper proposed a Bayesian （Bayes ）-based method to optimize the long-term and short-term memory （LSTM ） network.The method first preprocessed the original monitoring data of crown settlement and peripheral convergence，then constructed the initial LSTM model of crown settlement and peripheral convergence of highway tunnels，and used …

Marcus Wallace V. Patriot Federal Credit Union

2024 Decisions

USDC for the Middle District of Pennsylvania