Digital Commons Network^™

Investigating The Impacts Of Bin Variability On Particle Size Distributions In Multiphase Eulerian-Eulerian Simulations, Wilbert Alexander Cruz

Master's Theses (2009 -)

In this study, a 3D steady-state Eulerian-Eulerian simulation was developed to investigate flow performance in a dilute pneumatic conveying system. The investigation focused on two main objectives: (1) assessing the influence of bin selection on solution accuracy for representing the polydisperse mixture, and (2) exploring methods to simplify the modeling of polydisperse particles in the simulation by utilizing a mean diameter derived from the mixture’s particle size distribution. The system's geometry and initial boundary conditions featured a 10.6 m long, 150 mm diameter horizontal pipe with both gaseous and solid phases initially moving at 27 m/s . The steady-state simulation …

In Vitro Comparison Of Cellular Cytoxicity Of Conventional Vs. Cad/Cam Denture Base Materials, Zainab Hill Albasry

Master's Theses (2009 -)

Aim: Adverse reactions and local irritation of the oral mucosa to prostheses constructed from PMMA include allergic response, erythema, and a burning sensation of the tongue and mucosal tissues. Evidence on the cytotoxic effects of digitally manufactured denture base materials remains scarce. The aim of this study was to evaluate and compare the cytotoxic effects of CAD/CAM fabricated denture bases versus conventionally heat-cured acrylic resin materials. Materials and Methods: In total, 75 disks of five different denture resin materials – 15 disks per group were prepared: Ivocap (group 1; control), Ivotion denture base (group 2), Lucitone 3D denture base (group …

Comprehensive Behavioral Intervention For Tics Specialty Clinic Outcomes, Brandon Xavier Pitts

Master's Theses (2009 -)

Tics are abrupt, repetitive, and non-rhythmic movements (motor tics) and vocalizations (vocal tics). Persistent (Chronic) Tic Disorders (PTDs), which include conditions such as Tourette Disorder (TD), are characterized by involuntary motor and vocal tics. PTDs are associated with a myriad of adverse social repercussions, reduced quality of life, and concurrent psychiatric diagnoses, and occur in approximately 1.1% to 4.8% of the global population. Comprehensive Behavioral Intervention for Tics (CBIT) stands as the primary nonpharmacological therapeutic approach for tics. Although the efficacy of CBIT has been established in multiple large-scale randomized control trials (RCTs), there is a paucity of research scrutinizing …

The Power And Promise Of Patient-Derived Xenografts Of Human Breast Cancer, Michael T Lewis, Carlos Caldas

Faculty, Staff and Students Publications

In 2016, a group of researchers engaged in the development of patient-derived xenografts (PDXs) of human breast cancer provided a comprehensive review of the state of the field. In that review, they summarized the clinical problem that PDXs might address, the technical approaches to their generation (including a discussion of host animals and transplant conditions tested), and presented transplantation success (take) rates across groups and across transplantation conditions. At the time, there were just over 500 unique PDX models created by these investigators representing all three clinically defined subtypes (ER

Cholesterol 25-Hydroxylase Mediates Neuroinflammation And Neurodegeneration In A Mouse Model Of Tauopathy, Danira Toral-Rios, Justin M Long, Jason D Ulrich, Jinsheng Yu, Michael R Strickland, Xianlin Han, David M Holtzman, Anil G Cashikar, Steven M Paul

2020-Current year OA Pubs

Alzheimer's disease (AD) is characterized by amyloid plaques and neurofibrillary tangles, in addition to neuroinflammation and changes in brain lipid metabolism. 25-Hydroxycholesterol (25-HC), a known modulator of both inflammation and lipid metabolism, is produced by cholesterol 25-hydroxylase encoded by Ch25h expressed as a "disease-associated microglia" signature gene. However, whether Ch25h influences tau-mediated neuroinflammation and neurodegeneration is unknown. Here, we show that in the absence of Ch25h and the resultant reduction in 25-HC, there is strikingly reduced age-dependent neurodegeneration and neuroinflammation in the hippocampus and entorhinal/piriform cortex of PS19 mice, which express the P301S mutant human tau transgene. Transcriptomic analyses of …

Cognitive Outcomes Of Children With Sagittal Craniosynostosis Treated With Either Endoscopic Or Open Calvarial Vault Surgery, Suresh N Magge, Annahita R Fotouhi, Virginia Allhusen, Brent R Collett, Gary B Skolnick, Sybill D Naidoo, Matthew D Smyth, Robert F Keating, Raj Vyas, Gary F Rogers, Kamlesh B Patel

2020-Current year OA Pubs

IMPORTANCE: Several studies have reported a higher incidence of neurodevelopmental delays and cognitive deficits in patients with single-suture craniosynostosis; however, there are few studies examining the associations of repair type with cognitive outcomes.

OBJECTIVE: To measure differences in neuropsychological outcomes between school-age children who were treated for sagittal craniosynostosis and unaffected controls and explore differences in cognitive function among children with sagittal craniosynostosis who were previously treated with either endoscopic strip craniectomy or open calvarial vault surgery.

DESIGN, SETTING, AND PARTICIPANTS: This cohort study was performed between 2018 and 2022. Eligible participants included patients aged 5 to 17 years who …

Brain High-Throughput Multi-Omics Data Reveal Molecular Heterogeneity In Alzheimer's Disease, Abdallah M. Eteleeb, Brenna C. Novotny, Carolina Soriano Tarraga, Christopher Sohn, Eliza Dhungel, Logan Brase, Aasritha Nallapu, Jared Buss, Fabiana Farias, Kristy Bergmann, Joseph Bradley, Joanne Norton, Jen Gentsch, Fengxian Wang, Albert A. Davis, John C. Morris, Celeste M. Karch, Richard J. Perrin, Bruno A. Benitez, Oscar Harari

2020-Current year OA Pubs

Unbiased data-driven omic approaches are revealing the molecular heterogeneity of Alzheimer disease. Here, we used machine learning approaches to integrate high-throughput transcriptomic, proteomic, metabolomic, and lipidomic profiles with clinical and neuropathological data from multiple human AD cohorts. We discovered 4 unique multimodal molecular profiles, one of them showing signs of poor cognitive function, a faster pace of disease progression, shorter survival with the disease, severe neurodegeneration and astrogliosis, and reduced levels of metabolomic profiles. We found this molecular profile to be present in multiple affected cortical regions associated with higher Braak tau scores and significant dysregulation of synapse-related genes, endocytosis, …

Highly Accurate Blood Test For Alzheimer's Disease Is Similar Or Superior To Clinical Cerebrospinal Fluid Tests, Nicolas R Barthélemy, Suzanne E Schindler, Yingxin He, Benjamin Saef, Rachel L Henson, Charles D Chen, Brian A Gordon, Yan Li, Tammie L S Benzinger, John C Morris, Randall J Bateman, Et Al.

2020-Current year OA Pubs

With the emergence of Alzheimer's disease (AD) disease-modifying therapies, identifying patients who could benefit from these treatments becomes critical. In this study, we evaluated whether a precise blood test could perform as well as established cerebrospinal fluid (CSF) tests in detecting amyloid-β (Aβ) plaques and tau tangles. Plasma %p-tau217 (ratio of phosporylated-tau217 to non-phosphorylated tau) was analyzed by mass spectrometry in the Swedish BioFINDER-2 cohort (n = 1,422) and the US Charles F. and Joanne Knight Alzheimer Disease Research Center (Knight ADRC) cohort (n = 337). Matched CSF samples were analyzed with clinically used and FDA-approved automated immunoassays for Aβ42/40 …

Automated Model Building And Protein Identification In Cryo-Em Maps, Kiarash Jamali, Lukas Käll, Rui Zhang, Alan Brown, Dari Kimanius, Sjors H W Scheres

2020-Current year OA Pubs

Interpreting electron cryo-microscopy (cryo-EM) maps with atomic models requires high levels of expertise and labour-intensive manual intervention in three-dimensional computer graphics programs

Dna Combing Versus Dna Spreading And The Separation Of Sister Chromatids, Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, Alessandro Vindigni

2020-Current year OA Pubs

DNA combing and DNA spreading are two central approaches for studying DNA replication fork dynamics genome-wide at single-molecule resolution by distributing labeled genomic DNA on coverslips or slides for immunodetection. Perturbations in DNA replication fork dynamics can differentially affect either leading or lagging strand synthesis, for example, in instances where replication is blocked by a lesion or obstacle on only one of the two strands. Thus, we sought to investigate whether the DNA combing and/or spreading approaches are suitable for resolving adjacent sister chromatids during DNA replication, thereby enabling the detection of DNA replication dynamics within individual nascent strands. To …

Lipprint: Using Lip Movements As A Silent Password, Ahmed Ketab, Nidhal K. El Abbadi

Mesopotamian Journal of CyberSecurity

Authentication and confidentiality are critical elements in many systems, and passwords are used to protect these systems. One way to enter the password into the system is via voice. The problem with this type of password is that people listen to it easily. The general purpose of this study was to make the password based on lip movement instead of sound. To address this problem, a visual speech recognition (VSR) system was proposed that detects speech from lip movement as a silent password. The proposed system consists of preprocessing the captured video via the proposed algorithms and feature extraction and …

Artificial Intelligence And Cybersecurity In Face Sale Contracts: Legal Issues And Frameworks, Lobna Abdalhusen Easa Al-Saeedi, Doaa Fadhil Gatea Albo Mohammed, Firas Jamal Shakir, Faris Kamil Hasan, Faris Kamil Hasan, Yahya Layth Khaleel, Mustafa Abdulfattah Habeeb

Mesopotamian Journal of CyberSecurity

The sale of facial features is a new modern contractual development that resulted from the fast transformations in technology, leading to legal, and ethical obligations. As the need rises for human faces to be used in robots, especially in relation to industries that necessitate direct human interaction, like hospitality and retail, the potential of Artificial Intelligence (AI) generated hyper realistic facial images poses legal and cybersecurity challenges. This paper examines the legal terrain that has developed in the sale of real and AI generated human facial features, and specifically the risks of identity fraud, data misuse and privacy violations. Deep …

Improved Deep Learning Model Based Real-Time Recognition Of Arabic Sign Language, Nehal F. Attia, Mohamed Talaat Faheem Said Ahmed, Mahmoud A. M. Alshewimy

Journal of Engineering Research

Sign Language (SL) recognition plays a crucial role in facilitating communication and inclusivity for the hearing-impaired community. In this paper, we introduce a novel approach that incorporates two distinct activation functions—Exponential Linear Unit (ELU) and HardSwish-ELU—to enhance recognition using the pre-trained YOLOv5 object recognition model. ELU is integrated into the intermediate layers of the YOLOv5 architecture, addressing the vanishing gradient problem and capturing more expressive features. The HardSwish activation function, known for combining the advantages of ReLU and LeakyReLU, is employed for the final classification layer to enhance discriminative power. Throughout the training process, we use the SGD-based optimizer to …

Investigation Into The Impact Of Ammonia Hydroxide On Performance And Emissions In Compression Ignition Engines Utilizing Diesel/Biodiesel Blends, Medhat Elkelawy Prof. Dr, Eng., Hagar Alm-Eldin Bastawissi, Mohammed Osama Elsamadony Dr. Eng., Abdallah Salem Abdalhadi

Journal of Engineering Research

In recent times, there has been a surge in scientific endeavors aimed at combating global warming. Various methods have been employed to address this issue, including the substitution of fossil fuels with more environmentally sustainable alternatives and the combination of different fuel types. This can be achieved through the integration of innovative injection systems and the simultaneous combustion of alternative fuels alongside fossil fuels, or by modifying fuel injection systems such as in the PCCI, RCCI, or HCCI systems. In a particular research investigation, a blend of ammonia hydroxide and diesel, with volume percentages of 7.5% and 92.5% respectively, was …

Effect Of Corrugation Properties On The Flexural Behavior Of Small-Scale Mono-Symmetric Steel Girders With Corrugated Webs, Ahmed Elgendy, Ahmed M. El Hadidy, Dr. Mahmoud Hassan Elboghdadi

Journal of Engineering Research

Steel girders with corrugated webs have been extensively researched and used in a variety of applications during the last few decades, including bridges and industrial buildings. Many studies explored the behavior of double symmetric girders with corrugated webs, but only a few articles used unequal flanges. Furthermore, the majority of research focuses on large-scale girders such as bridge girders, with just a few publications considering small-scale girders that may be employed in traditional construction applications. Additionally, performed investigations that consider the flexural behavior focused their studies on the effect of varying the dimensions of flanges without considering the effect of …

Finite Element Investigation For The Flexural Behavior Of Small-Scale Mono-Symmetric Steel Girders With Corrugated Webs, Ahmed H. Elgendy, Ahmed M. El Hadidy, Dr. Mahmoud Hassan Elboghdadi

Journal of Engineering Research

In the last decades, steel girders with corrugated webs have been widely investigated and implemented in many applications such as bridges and industrial facilities. Many researchers investigated the flexural behavior of traditional doubly symmetric girders with corrugated webs, but a very limited number of investigations considered the usage of unequal flanges. In addition, for most cases the performed investigations focus on the behavior of large-scale girders similar to bridge girders, while few papers considered small-scale girders that could be used in traditional structures. Thus, the objective of this paper is to investigate the lateral torsional buckling behavior of small-scale unsymmetric …

A Soft Two-Layers Voting Model For Fake News Detection, Hnin Ei Wynne, Khaing Thanda Swe

Journal of Engineering Research

The proliferation of fake news has become a complex and challenge problem in recent year, and presenting various unsolved issues within the research domain. Among these challenges, a critical concern is the development of effective models capable of accurately distinguish between fake and real news. While numerous techniques have been proposed for fake news detection, achieving optimal accuracy remains elusive. This paper introduces a novel fake news detection approach employing a two-layered weighted voting classifier. In contrast to conventional methods that assign equal weights to all classifiers, our proposed approach utilizes a selective weighting approach to solve the current issue. …

Chanticleer | March 2024, Jacksonville State University

Chanticleer

No abstract provided.

A Review On Recent Deep Learning-Based Semantic Segmentation For Urban Greenness Measurement, Doo Hong Lee, Hye Yeon Park, Joonwhoan Lee

Landscape Architecture and Environmental Planning Student Research

Accurate urban green space (UGS) measurement has become crucial for landscape analysis. This paper reviews the recent technological breakthroughs in deep learning (DL)-based semantic segmentation, emphasizing efficient landscape analysis, and integrating greenness measurements. It explores quantitative greenness measures applied through semantic segmentation, categorized into the plan view- and the perspective view-based methods, like the Land Class Classification (LCC) with green objects and the Green View Index (GVI) based on street photographs. This review navigates from traditional to modern DL-based semantic segmentation models, illuminating the evolution of the urban greenness measures and segmentation tasks for advanced landscape analysis. It also presents …

Tennessee Jail Summary Report, March 2024, Tennessee. Department Of Correction.

Jail Summary Reports

No abstract provided.

The Impact Of Minimalist Design On Consumer’S Brand Expectations, Carolina L. Guerrero

Honors College Theses

In order for companies to be more effective in reaching their target market amongst growing competition, they must successfully construct their product’s packaging to appeal to the consumer’s eye and demonstrate their desired qualities. With packaging design aesthetics falling into the two categories of minimalism or maximalism, a relationship may be established between the design aesthetic and the perceptions a certain design imposes. This thesis will conduct an experimental design with fabricated product mockups exemplifying minimalism and maximalism designs in personal care and prepackaged food products. These designs will be evaluated by respondents for different perceptions based on the first …

Proteoglycan Dysfunction: A Common Link Between Intervertebral Disc Degeneration And Skeletal Dysplasia, Kimheak Sao, Makarand V. Risbud

Department of Orthopaedic Surgery Faculty Papers

Proteoglycans through their sulfated glycosaminoglycans regulate cell-matrix signaling during tissue development, regeneration, and degeneration processes. Large extracellular proteoglycans such as aggrecan, versican, and perlecan are especially important for the structural integrity of the intervertebral disc and cartilage during development. In these tissues, proteoglycans are responsible for hydration, joint flexibility, and the absorption of mechanical loads. Loss or reduction of these molecules can lead to disc degeneration and skeletal dysplasia, evident from loss of disc height or defects in skeletal development respectively. In this review, we discuss the common proteoglycans found in the disc and cartilage and elaborate on various murine …

Quarterly Report - 3rd Quarter, January 1 - March 31, 2024, Etsu Foundation, East Tennessee State University

ETSU Foundation Quarterly Reports

No abstract provided.

Efficacy Of Programs Designed To Reduce The Incidence Of Premarital Sexual Behavior Among Adolescents: A Systematic Review, Desy Ayu Wardani, Siti Khuzaimah Ahmad Sharoni, Endang Triyanto

Jurnal Keperawatan Indonesia

The incidence of premarital sexual behavior worldwide is increasing despite the fact that it is known that it may cause health and psychological problems. Hence, interventions are needed to reduce the incidence of premarital sexual behavior. The aim of this study was to provide an overview of the reported interventions used to reduce the incidence of premarital sexual behavior in adolescents and identify the implications for nursing practice. A systematic review was conducted using The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. The Scopus, Science Direct, Web of Science, and ProQuest databases were searched using the keywords …

Tennessee Felon Population Update, April 2024, Tennessee. Department Of Correction.

Felon Population Reports

No abstract provided.

An Investigation Of The Critical Factors That Influence Knowledge Mobilization Success In Agri-Food Supply Chains, Huilan Chen, Shaofeng Liu, Guoqing Zhao, Uchitha Jayawickrama, Xiaofang Wu

Plymouth Business School

Agri-food supply chains (AFSCs) are essential for addressing global food security and promoting the United Nation’s Sustainable Development Goal of reducing hunger. These chains stand out because they deal with perishable goods that have limited shelf life and are subjected to erratic agricultural situations, such as fluc-tuating weather. To preserve sustainability and competitiveness, innovative approaches such as cross-border knowledge mobilization are essential for effective AFSC management. To identify the elements essential to effective knowledge mobilization within AFSCs, this study explores the dynamics of this process. Eleven poten-tial critical success factors (CSFs) are identified and analyzed by using questionnaire surveys to …

Gigacollector: A Real-Time, Temporally Coherent Framework Forwi-Fi Environment Control, Data Collection, And Ml Inference, An Vu

Computer Science and Engineering Master's Theses

Wi-Fi is the primary wireless communication method for the majority of devices in both residential and commercial settings. The number of devices continues to increase, making latency, bandwidth, and security difficult to manage and balance to provide satisfactory performance for all users. Novel methods that rely on the collection of data from the networking stack have been developed in research settings to analyze and predict key parameters and network state to improve communication efficiency. However, crucial processes such as experimentation, data collection, and performance analysis have often been performed manually on offline data.

This thesis presents GigaCollector, a scalable end-to-end …

Learning Management Based On Murdoch Integrated Approach (Mia) With Graphic Organizers To Develop English Reading Comprehension Ability Of Grade 3 Students, Fatin Hayihama, Juraisiri Choorak, Nisita Rittapirom

Journal of Education Studies

The purposes of this research were to: 1) compare the students’ English reading comprehension abilities between before and after learning management, 2) compare the students’ English reading comprehension abilities after learning management with the criteria of 70%, and 3) study the students’ satisfaction on learning management based on Murdoch Integrated Approach (MIA) with graphic organizers. The sample group is comprised of 26 grade 3 students at Thesaban 3 (Wat Sala Huayang) in the first semester of the academic year 2023, by using cluster random sampling. The research instruments consisted of 1) 5 lesson plans in English subject, unit 2 My …

Did Covid-19 Disrupt The Stock Market Return And Volatility? A Meta-Analytic Approach, Masagus M. Ridhwan, Solikin M. Juhro, Affandi Ismail, Peter Nijkamp, Kelvin Ramadhan Hidayat

Bulletin of Monetary Economics and Banking

We provide a quantitative synthesis of the literature utilizing meta-regression analysis on the measurable effect of the combined health and economic crisis due to the COVID-19 pandemic on stock market returns and volatility. This study is conducted based on 104 studies published during the period 2020 to 2022. We find strong evidence of a negative publication bias for COVID-19 impacts on stock market returns and a positive bias on volatility. We document that COVID-19 has a moderate negative effect on stock market returns. Estimates based on intraday stock returns show a greater effect compared to those using daily returns, whereas …

Konstitusionalitas Open Legal Policy Mengenai Kebijakan Earmarking Pajak Karbon Di Indonesia, Mahaarum Kusuma Pertiwi, Praditya Janu Wisaksono

Jurnal Hukum & Pembangunan

The Law on Harmonization of Tax Regulation mandates government regulation to regulate the allocation of carbon tax revenue for controlling climate change. Based on Article 13 paragraph (12) and paragraph (15) letter b of the Law on Harmonization of Tax Regulation as well as the Constitutional Court's judicial review decisions regarding open legal policies and tax earmarking, this article answers questions regarding the legal construction of open legal policy options in Indonesia which confirms further delegation of carbon tax earmarking through government regulation. The government may allocate state revenue from carbon tax to control climate change. This means that carbon …