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Impact Of Obesity And Age On Mouse Corneal Innervation At The Epithelial-Stromal Interface, Justin A Courson, Rolando E Rumbaut, Alan R Burns May 2024

Impact Of Obesity And Age On Mouse Corneal Innervation At The Epithelial-Stromal Interface, Justin A Courson, Rolando E Rumbaut, Alan R Burns

Faculty, Staff and Students Publications

PURPOSE: The corneal epithelium is the most highly innervated structure in the body. Previously, we reported a novel event whereby stromal axons fuse with basal epithelial cells, limiting nerve penetration into the epithelium. Although corneal-epithelial nerves undergo changes in sensitivity and distribution throughout life and in response to an obesogenic diet, it is unknown if neuronal-epithelial cell fusion is altered. Here, we sought to determine if neuronal-epithelial cell fusion frequency correlates with obesogenic diet consumption and age.

METHODS: Corneas were collected from C57BL/6 mice and evaluated for neuronal-epithelial cell fusion frequency using serial block-face scanning electron microscopy. To assess the …


Genome-Wide Association Analyses Identify 95 Risk Loci And Provide Insights Into The Neurobiology Of Post-Traumatic Stress Disorder, Caroline M Nievergelt, Adam X Maihofer, Elizabeth G Atkinson, Chia-Yen Chen, Karmel W Choi, Jonathan R I Coleman, Nikolaos P Daskalakis, Laramie E Duncan, Renato Polimanti, Cindy Aaronson, Ananda B Amstadter, Soren B Andersen, Ole A Andreassen, Paul A Arbisi, Allison E Ashley-Koch, S Bryn Austin, Esmina Avdibegoviç, Dragan Babić, Silviu-Alin Bacanu, Dewleen G Baker, Anthony Batzler, Jean C Beckham, Sintia Belangero, Corina Benjet, Carisa Bergner, Linda M Bierer, Joanna M Biernacka, Laura J Bierut, Jonathan I Bisson, Marco P Boks, Elizabeth A Bolger, Amber Brandolino, Gerome Breen, Rodrigo Affonseca Bressan, Richard A Bryant, Angela C Bustamante, Jonas Bybjerg-Grauholm, Marie Bækvad-Hansen, Anders D Børglum, Sigrid Børte, Leah Cahn, Joseph R Calabrese, Jose Miguel Caldas-De-Almeida, Chris Chatzinakos, Sheraz Cheema, Sean A P Clouston, Lucía Colodro-Conde, Brandon J Coombes, Carlos S Cruz-Fuentes, Anders M Dale, Shareefa Dalvie, Lea K Davis, Jürgen Deckert, Douglas L Delahanty, Michelle F Dennis, Frank Desarnaud, Christopher P Dipietro, Seth G Disner, Anna R Docherty, Katharina Domschke, Grete Dyb, Alma Džubur Kulenović, Howard J Edenberg, Alexandra Evans, Chiara Fabbri, Negar Fani, Lindsay A Farrer, Adriana Feder, Norah C Feeny, Janine D Flory, David Forbes, Carol E Franz, Sandro Galea, Melanie E Garrett, Bizu Gelaye, Joel Gelernter, Elbert Geuze, Charles F Gillespie, Slavina B Goleva, Scott D Gordon, Aferdita Goçi, Lana Ruvolo Grasser, Camila Guindalini, Magali Haas, Saskia Hagenaars, Michael A Hauser, Andrew C Heath, Sian M J Hemmings, Victor Hesselbrock, Ian B Hickie, Kelleigh Hogan, David Michael Hougaard, Hailiang Huang, Laura M Huckins, Kristian Hveem, Miro Jakovljević, Arash Javanbakht, Gregory D Jenkins, Jessica Johnson, Ian Jones, Tanja Jovanovic, Karen-Inge Karstoft, Milissa L Kaufman, James L Kennedy, Ronald C Kessler, Alaptagin Khan, Nathan A Kimbrel, Anthony P King, Nastassja Koen, Roman Kotov, Henry R Kranzler, Kristi Krebs, William S Kremen, Pei-Fen Kuan, Bruce R Lawford, Lauren A M Lebois, Kelli Lehto, Daniel F Levey, Catrin Lewis, Israel Liberzon, Sarah D Linnstaedt, Mark W Logue, Adriana Lori, Yi Lu, Benjamin J Luft, Michelle K Lupton, Jurjen J Luykx, Iouri Makotkine, Jessica L Maples-Keller, Shelby Marchese, Charles Marmar, Nicholas G Martin, Gabriela A Martínez-Levy, Kerrie Mcaloney, Alexander Mcfarlane, Katie A Mclaughlin, Samuel A Mclean, Sarah E Medland, Divya Mehta, Jacquelyn Meyers, Vasiliki Michopoulos, Elizabeth A Mikita, Lili Milani, William Milberg, Mark W Miller, Rajendra A Morey, Charles Phillip Morris, Ole Mors, Preben Bo Mortensen, Mary S Mufford, Elliot C Nelson, Merete Nordentoft, Sonya B Norman, Nicole R Nugent, Meaghan O'Donnell, Holly K Orcutt, Pedro M Pan, Matthew S Panizzon, Gita A Pathak, Edward S Peters, Alan L Peterson, Matthew Peverill, Robert H Pietrzak, Melissa A Polusny, Bernice Porjesz, Abigail Powers, Xue-Jun Qin, Andrew Ratanatharathorn, Victoria B Risbrough, Andrea L Roberts, Alex O Rothbaum, Barbara O Rothbaum, Peter Roy-Byrne, Kenneth J Ruggiero, Ariane Rung, Heiko Runz, Bart P F Rutten, Stacey Saenz De Viteri, Giovanni Abrahão Salum, Laura Sampson, Sixto E Sanchez, Marcos Santoro, Carina Seah, Soraya Seedat, Julia S Seng, Andrey Shabalin, Christina M Sheerin, Derrick Silove, Alicia K Smith, Jordan W Smoller, Scott R Sponheim, Dan J Stein, Synne Stensland, Jennifer S Stevens, Jennifer A Sumner, Martin H Teicher, Wesley K Thompson, Arun K Tiwari, Edward Trapido, Monica Uddin, Robert J Ursano, Unnur Valdimarsdóttir, Miranda Van Hooff, Eric Vermetten, Christiaan H Vinkers, Joanne Voisey, Yunpeng Wang, Zhewu Wang, Monika Waszczuk, Heike Weber, Frank R Wendt, Thomas Werge, Michelle A Williams, Douglas E Williamson, Bendik S Winsvold, Sherry Winternitz, Christiane Wolf, Erika J Wolf, Yan Xia, Ying Xiong, Rachel Yehuda, Keith A Young, Ross Mcd Young, Clement C Zai, Gwyneth C Zai, Mark Zervas, Hongyu Zhao, Lori A Zoellner, John-Anker Zwart, Terri Deroon-Cassini, Sanne J H Van Rooij, Leigh L Van Den Heuvel, Murray B Stein, Kerry J Ressler, Karestan C Koenen May 2024

Genome-Wide Association Analyses Identify 95 Risk Loci And Provide Insights Into The Neurobiology Of Post-Traumatic Stress Disorder, Caroline M Nievergelt, Adam X Maihofer, Elizabeth G Atkinson, Chia-Yen Chen, Karmel W Choi, Jonathan R I Coleman, Nikolaos P Daskalakis, Laramie E Duncan, Renato Polimanti, Cindy Aaronson, Ananda B Amstadter, Soren B Andersen, Ole A Andreassen, Paul A Arbisi, Allison E Ashley-Koch, S Bryn Austin, Esmina Avdibegoviç, Dragan Babić, Silviu-Alin Bacanu, Dewleen G Baker, Anthony Batzler, Jean C Beckham, Sintia Belangero, Corina Benjet, Carisa Bergner, Linda M Bierer, Joanna M Biernacka, Laura J Bierut, Jonathan I Bisson, Marco P Boks, Elizabeth A Bolger, Amber Brandolino, Gerome Breen, Rodrigo Affonseca Bressan, Richard A Bryant, Angela C Bustamante, Jonas Bybjerg-Grauholm, Marie Bækvad-Hansen, Anders D Børglum, Sigrid Børte, Leah Cahn, Joseph R Calabrese, Jose Miguel Caldas-De-Almeida, Chris Chatzinakos, Sheraz Cheema, Sean A P Clouston, Lucía Colodro-Conde, Brandon J Coombes, Carlos S Cruz-Fuentes, Anders M Dale, Shareefa Dalvie, Lea K Davis, Jürgen Deckert, Douglas L Delahanty, Michelle F Dennis, Frank Desarnaud, Christopher P Dipietro, Seth G Disner, Anna R Docherty, Katharina Domschke, Grete Dyb, Alma Džubur Kulenović, Howard J Edenberg, Alexandra Evans, Chiara Fabbri, Negar Fani, Lindsay A Farrer, Adriana Feder, Norah C Feeny, Janine D Flory, David Forbes, Carol E Franz, Sandro Galea, Melanie E Garrett, Bizu Gelaye, Joel Gelernter, Elbert Geuze, Charles F Gillespie, Slavina B Goleva, Scott D Gordon, Aferdita Goçi, Lana Ruvolo Grasser, Camila Guindalini, Magali Haas, Saskia Hagenaars, Michael A Hauser, Andrew C Heath, Sian M J Hemmings, Victor Hesselbrock, Ian B Hickie, Kelleigh Hogan, David Michael Hougaard, Hailiang Huang, Laura M Huckins, Kristian Hveem, Miro Jakovljević, Arash Javanbakht, Gregory D Jenkins, Jessica Johnson, Ian Jones, Tanja Jovanovic, Karen-Inge Karstoft, Milissa L Kaufman, James L Kennedy, Ronald C Kessler, Alaptagin Khan, Nathan A Kimbrel, Anthony P King, Nastassja Koen, Roman Kotov, Henry R Kranzler, Kristi Krebs, William S Kremen, Pei-Fen Kuan, Bruce R Lawford, Lauren A M Lebois, Kelli Lehto, Daniel F Levey, Catrin Lewis, Israel Liberzon, Sarah D Linnstaedt, Mark W Logue, Adriana Lori, Yi Lu, Benjamin J Luft, Michelle K Lupton, Jurjen J Luykx, Iouri Makotkine, Jessica L Maples-Keller, Shelby Marchese, Charles Marmar, Nicholas G Martin, Gabriela A Martínez-Levy, Kerrie Mcaloney, Alexander Mcfarlane, Katie A Mclaughlin, Samuel A Mclean, Sarah E Medland, Divya Mehta, Jacquelyn Meyers, Vasiliki Michopoulos, Elizabeth A Mikita, Lili Milani, William Milberg, Mark W Miller, Rajendra A Morey, Charles Phillip Morris, Ole Mors, Preben Bo Mortensen, Mary S Mufford, Elliot C Nelson, Merete Nordentoft, Sonya B Norman, Nicole R Nugent, Meaghan O'Donnell, Holly K Orcutt, Pedro M Pan, Matthew S Panizzon, Gita A Pathak, Edward S Peters, Alan L Peterson, Matthew Peverill, Robert H Pietrzak, Melissa A Polusny, Bernice Porjesz, Abigail Powers, Xue-Jun Qin, Andrew Ratanatharathorn, Victoria B Risbrough, Andrea L Roberts, Alex O Rothbaum, Barbara O Rothbaum, Peter Roy-Byrne, Kenneth J Ruggiero, Ariane Rung, Heiko Runz, Bart P F Rutten, Stacey Saenz De Viteri, Giovanni Abrahão Salum, Laura Sampson, Sixto E Sanchez, Marcos Santoro, Carina Seah, Soraya Seedat, Julia S Seng, Andrey Shabalin, Christina M Sheerin, Derrick Silove, Alicia K Smith, Jordan W Smoller, Scott R Sponheim, Dan J Stein, Synne Stensland, Jennifer S Stevens, Jennifer A Sumner, Martin H Teicher, Wesley K Thompson, Arun K Tiwari, Edward Trapido, Monica Uddin, Robert J Ursano, Unnur Valdimarsdóttir, Miranda Van Hooff, Eric Vermetten, Christiaan H Vinkers, Joanne Voisey, Yunpeng Wang, Zhewu Wang, Monika Waszczuk, Heike Weber, Frank R Wendt, Thomas Werge, Michelle A Williams, Douglas E Williamson, Bendik S Winsvold, Sherry Winternitz, Christiane Wolf, Erika J Wolf, Yan Xia, Ying Xiong, Rachel Yehuda, Keith A Young, Ross Mcd Young, Clement C Zai, Gwyneth C Zai, Mark Zervas, Hongyu Zhao, Lori A Zoellner, John-Anker Zwart, Terri Deroon-Cassini, Sanne J H Van Rooij, Leigh L Van Den Heuvel, Murray B Stein, Kerry J Ressler, Karestan C Koenen

Faculty, Staff and Students Publications

Post-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability than most other psychiatric disorders. The contribution to biological understanding from previous genetic studies has thus been limited. We performed a multi-ancestry meta-analysis of genome-wide association studies across 1,222,882 individuals of European ancestry (137,136 cases) and 58,051 admixed individuals with African and Native American ancestry (13,624 cases). We identified 95 genome-wide significant loci (80 new). Convergent multi-omic approaches identified 43 potential causal genes, broadly classified as neurotransmitter and ion channel synaptic modulators (for example, GRIA1, GRM8 and CACNA1E), developmental, axon guidance and transcription factors (for example, FOXP2, EFNA5 and DCC), …


Explaining Misinformation Detection Using Large Language Models, Vishnu S. Pendyala, Christopher E. Hall May 2024

Explaining Misinformation Detection Using Large Language Models, Vishnu S. Pendyala, Christopher E. Hall

Faculty Research, Scholarly, and Creative Activity

Large language models (LLMs) are a compressed repository of a vast corpus of valuable information on which they are trained. Therefore, this work hypothesizes that LLMs such as Llama, Orca, Falcon, and Mistral can be used for misinformation detection by making them cross-check new information with the repository on which they are trained. Accordingly, this paper describes the findings from the investigation of the abilities of LLMs in detecting misinformation on multiple datasets. The results are interpreted using explainable AI techniques such as Local Interpretable Model-Agnostic Explanations (LIME), SHapley Additive exPlanations (SHAP), and Integrated Gradients. The LLMs themselves are also …


Validation Of Satellite-Based Cloud Phase Distributions Using Global-Scale In Situ Airborne Observations, Dao Wang, Ching An Yang, Minghui Diao May 2024

Validation Of Satellite-Based Cloud Phase Distributions Using Global-Scale In Situ Airborne Observations, Dao Wang, Ching An Yang, Minghui Diao

Faculty Research, Scholarly, and Creative Activity

Understanding distributions of cloud thermodynamic phases is important for accurately representing cloud radiative effects and cloud feedback in a changing climate. Satellite-based cloud phase data have been frequently used to compare with climate models, yet few studies validated them against in situ observations at a near-global scale. This study aims to validate three satellite-based cloud phase products using a compositive in situ airborne data set developed from 11 flight campaigns. Latitudinal-altitudinal cross sections of cloud phase occurrence frequencies are examined. The Cloud–Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) show the most similar vertical profiles of ice phase frequencies compared …


Transforming Academic Librarianship Through Ai Reskilling: Insights From The Gpt-4 Exploration Program, Leo S. Lo May 2024

Transforming Academic Librarianship Through Ai Reskilling: Insights From The Gpt-4 Exploration Program, Leo S. Lo

University Libraries & Learning Sciences Faculty and Staff Publications

The emergence of Artificial Intelligence (AI) in academic librarianship necessitates a corresponding evolution in librarians' competencies. This case study examines the GPT-4 Exploration Program at the University of New Mexico's College of University Libraries and Learning Sciences, which aimed to foster a culture of continuous learning and innovation by providing hands-on experience with advanced AI technology. Drawing on Malcolm Knowles' Adult Learning Principles, the program's structure and implementation are analyzed, highlighting the diverse range of projects undertaken by participants. The study reveals that effective AI reskilling involves cultivating a culture of continuous learning, adaptability, and collaborative exploration, anchored in a …


Single-Nucleotide Variant Calling In Single-Cell Sequencing Data With Monopogen, Jinzhuang Dou, Li Ding, Et Al. May 2024

Single-Nucleotide Variant Calling In Single-Cell Sequencing Data With Monopogen, Jinzhuang Dou, Li Ding, Et Al.

2020-Current year OA Pubs

Single-cell omics technologies enable molecular characterization of diverse cell types and states, but how the resulting transcriptional and epigenetic profiles depend on the cell's genetic background remains understudied. We describe Monopogen, a computational tool to detect single-nucleotide variants (SNVs) from single-cell sequencing data. Monopogen leverages linkage disequilibrium from external reference panels to identify germline SNVs and detects putative somatic SNVs using allele cosegregating patterns at the cell population level. It can identify 100 K to 3 M germline SNVs achieving a genotyping accuracy of 95%, together with hundreds of putative somatic SNVs. Monopogen-derived genotypes enable global and local ancestry inference …


Loss Of Katnal2 Leads To Ependymal Ciliary Hyperfunction And Autism-Related Phenotypes In Mice, Ryeonghwa Kang, Zachary Papadopoulos, Jonathan Kipnis, Et Al. May 2024

Loss Of Katnal2 Leads To Ependymal Ciliary Hyperfunction And Autism-Related Phenotypes In Mice, Ryeonghwa Kang, Zachary Papadopoulos, Jonathan Kipnis, Et Al.

2020-Current year OA Pubs

Autism spectrum disorders (ASD) frequently accompany macrocephaly, which often involves hydrocephalic enlargement of brain ventricles. Katnal2 is a microtubule-regulatory protein strongly linked to ASD, but it remains unclear whether Katnal2 knockout (KO) in mice leads to microtubule- and ASD-related molecular, synaptic, brain, and behavioral phenotypes. We found that Katnal2-KO mice display ASD-like social communication deficits and age-dependent progressive ventricular enlargements. The latter involves increased length and beating frequency of motile cilia on ependymal cells lining ventricles. Katnal2-KO hippocampal neurons surrounded by enlarged lateral ventricles show progressive synaptic deficits that correlate with ASD-like transcriptomic changes involving synaptic gene down-regulation. Importantly, early …


Red Flag Signs And Symptoms For Patients With Early-Onset Colorectal Cancer: A Systematic Review And Meta-Analysis, Joshua Demb, Cassandra D L Fritz, Yin Cao, Et Al. May 2024

Red Flag Signs And Symptoms For Patients With Early-Onset Colorectal Cancer: A Systematic Review And Meta-Analysis, Joshua Demb, Cassandra D L Fritz, Yin Cao, Et Al.

2020-Current year OA Pubs

IMPORTANCE: Early-onset colorectal cancer (EOCRC), defined as a diagnosis at younger than age 50 years, is increasing, and so-called red flag signs and symptoms among these individuals are often missed, leading to diagnostic delays. Improved recognition of presenting signs and symptoms associated with EOCRC could facilitate more timely diagnosis and impact clinical outcomes.

OBJECTIVE: To report the frequency of presenting red flag signs and symptoms among individuals with EOCRC, to examine their association with EOCRC risk, and to measure variation in time to diagnosis from sign or symptom presentation.

DATA SOURCES: PubMed/MEDLINE, Embase, CINAHL, and Web of Science were searched …


Reimagining Schoolwide Social And Emotional Learning Implementation In The Urban Setting: A Case Study Of A Massachusetts Elementary School, Molly Helene Duffy May 2024

Reimagining Schoolwide Social And Emotional Learning Implementation In The Urban Setting: A Case Study Of A Massachusetts Elementary School, Molly Helene Duffy

Graduate Doctoral Dissertations

For social and emotional learning (SEL) initiatives to have the greatest positive impact on students, they must be implemented schoolwide. There is an urgent need for schools to shift away from traditional SEL frameworks toward transformative SEL (TSEL). TSEL program implementation cannot be done in isolation; rather, it must be fueled by a shared vision and dedication to team learning. To conduct this study, the researcher employed the Collaborative for Academic, Social, and Emotional Learning (CASEL) Guide to Schoolwide SEL and Senge’s learning organization as a theory of change. The study sought to uncover gaps in schoolwide SEL implementation in …


The Private Litigation Impact Of New York’S Green Amendment, Evan Bianchi, Sean Di Luccio, Martin Lockman, Vincent Nolette May 2024

The Private Litigation Impact Of New York’S Green Amendment, Evan Bianchi, Sean Di Luccio, Martin Lockman, Vincent Nolette

Sabin Center for Climate Change Law

The increasing urgency of climate change, combined with federal environmental inaction under the Trump Administration, inspired a wave of environmental action at the state and local level. Building on the environmental movement of the 1970s, activists have pushed to amend more than a dozen state constitutions to include “green amendments” — self-executing individual rights to a clean environment. In 2022, New York activists succeeded, and New York’s Green Amendment (the NYGA) now provides that “Each person shall have a right to clean air and water, and a healthful environment.”

However, the power of the NYGA and similar green amendments turns …


Psychological Safety Of Pre-Licensure Nursing Students: A Longitudinal, Qualitative Study, Laura Butler May 2024

Psychological Safety Of Pre-Licensure Nursing Students: A Longitudinal, Qualitative Study, Laura Butler

Student Works

Background: Previous studies have explored the concept of psychological safety among pre-licensure nursing students; however, the literature is notably sparse on personal descriptions of pre-licensure nursing students’ experiences of psychological safety in clinical settings. Individual descriptions of psychological safety will provide added insight and understanding about the elements that shape psychological safety in pre-licensure nursing students.

Objectives: This research aimed to longitudinally explore pre-licensure nursing students' experiences of psychological safety during clinical rotations and how their experiences of psychological safety change over time.

Methods: This study used a longitudinal, qualitative, descriptive approach. Participants were recruited from a …


Prevalence And Associated Clinical Characteristics Of Walking-Related Motor, Cognitive, And Fatigability In Progressive Multiple Sclerosis: Baseline Results From The Cogex Study, Cintia Ramari, Mieke D’Hooge, Ulrik Dalgas, Anthony Feinstein, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy D. Chiaravalloti, Gary R. Cutter, John Deluca, Rachel Farrell, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Robert W. Motl, Maria A. Rocca, Brian M. Sandroff, Amber Salter, Daphne Kos, Peter Feys May 2024

Prevalence And Associated Clinical Characteristics Of Walking-Related Motor, Cognitive, And Fatigability In Progressive Multiple Sclerosis: Baseline Results From The Cogex Study, Cintia Ramari, Mieke D’Hooge, Ulrik Dalgas, Anthony Feinstein, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy D. Chiaravalloti, Gary R. Cutter, John Deluca, Rachel Farrell, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Robert W. Motl, Maria A. Rocca, Brian M. Sandroff, Amber Salter, Daphne Kos, Peter Feys

School of Health Professions

Background: People with progressive multiple sclerosis (PMS) present motor (eg, walking) and cognitive impairments, and report fatigue. Fatigue encompasses fatigability which is objectively measured by the capacity to sustain a motor or cognitive task. Objective: To investigate the prevalence of walking and cognitive fatigability (CF) and the associated clinical characteristics in a large sample of PMS patients. Methods: PMS patients (25-65 years old) were included from 11 sites (Europe and North America), having cognitive impairment (1.28 standard deviation below normative data for the symbol digit modality test [SDMT]). Walking fatigability (WF) was assessed using the distance walk index (DWI) and …


Call Me Telephone Triage Skills For Pediatricians Across Multiple Settings, Cody Clary, Jonathan Ermer, Rebecca Callahan, Kayla Heller, Luke Stephens, Margaret Kirkpatrick, Nehal Parikh, Cody Tigges, Madhuradhar Chegondi May 2024

Call Me Telephone Triage Skills For Pediatricians Across Multiple Settings, Cody Clary, Jonathan Ermer, Rebecca Callahan, Kayla Heller, Luke Stephens, Margaret Kirkpatrick, Nehal Parikh, Cody Tigges, Madhuradhar Chegondi

Presentations

Come explore current evidence surrounding telephone triage skills across a variety of settings and learn ways to teach these valuable skills while promoting best practices. Outpatient pediatricians, hospitalists, ICU physicians and ED providers all have telephone calls incorporated into their work. Often physicians are operating with very little training in this area, and methodology about teaching these skills to pediatric trainees is limited. We will highlight educational innovations at a variety of programs designed to improve resident and fellow education, sharing our results and providing opportunities for others to design their own content relevant to their own practice. Participants will …


Alternative Energy And Protein Feed Sources For Sheep And Cattle, Department Of Primary Industries And Regional Development, Western Australia May 2024

Alternative Energy And Protein Feed Sources For Sheep And Cattle, Department Of Primary Industries And Regional Development, Western Australia

Animal production and livestock factsheets

During dry times and drought there are a wide range of alternative feedstuffs producers may consider using to maintain stock. Some of these feeds can have health risks associated with them and should not be used as the sole food source as they often lack sufficient energy and protein.


Raising Middle School Students' Awareness Of Relationship Risks Associated With Technology, Reda Gerges May 2024

Raising Middle School Students' Awareness Of Relationship Risks Associated With Technology, Reda Gerges

Capstone Projects and Master's Theses

Increasing middle school students' awareness of relationship risks associated with electronic technology is the main focus of this capstone project. With the prevalence of technology in teenagers' lives, many may not fully grasp the potential dangers of digital communication with friends and romantic partners. Although there are many advantages to using smartphones, tablets, and other technologies, there may also be drawbacks. Physical health concerns, eye strain Digital eye fatigue, eye strain, and pain can result from prolonged screen use. Overuse of tablets and smartphones can lead to bad posture, which can cause back and neck pain. Sleep disturbances by inhibiting …


Teaching First Graders About Emotional Self-Regulation, Nayeli N. Garcia Salinas May 2024

Teaching First Graders About Emotional Self-Regulation, Nayeli N. Garcia Salinas

Capstone Projects and Master's Theses

This project focused on increasing the emotion regulation skills of six to seven-year-olds. Emotion regulation is “a person’s ability to effectively manage and respond to an emotional experience” (Rolston & Lloyd-Richardson, n.d.). In other words, it is when a person understands their emotions, is capable of controlling them, and has appropriate responses to the events that caused them. Emotion regulation is difficult for children, it is specifically difficult for children who are learning to adjust to school. School is a new environment that can cause children to feel strong emotions that they have not felt before, therefore making it challenging …


Adding Texture Through Historical Research: Using Dramaturgy To Aid In The Creation Of Elizabeth (Bess) Borney., Nyazia Brittany Martin May 2024

Adding Texture Through Historical Research: Using Dramaturgy To Aid In The Creation Of Elizabeth (Bess) Borney., Nyazia Brittany Martin

Electronic Theses and Dissertations

This thesis follows my work with the production The Old Settler by John Henry Redwood. This document explores my process as an actor, and how I decided to capitalize on an opportunity to study Dramaturgy and apply what I learned to my actors' process. In the pages of this thesis I present the pieces of my process, including my vocal and movement work based in Laban and Alexander Technique. I give personal examples of how my dive into dramaturgical work positively affected how I crafted the role of Elizabeth (Bess) Borney. I also detail the transition out of my work …


Educator Perceptions Of Blended Teacher Professional Development: A Case Study Of A Vertically Aligned Virtual Professional Learning Community., Aslean White May 2024

Educator Perceptions Of Blended Teacher Professional Development: A Case Study Of A Vertically Aligned Virtual Professional Learning Community., Aslean White

Electronic Theses and Dissertations

This case study describes the design and enactment of a job-embedded, blended learning professional development plan for teachers to facilitate the collaborative inquiry of a vertically aligned virtual professional learning community. The study is of relevance because it seeks to implement recommendations from recent research on online teacher professional development (Barnett, 2020; Lockee, 2020; Powell & Bodur, 2019) using a framework for support structures designed to engage learners in blended and online learning environments (Philipsen et al., 2019). This qualitative multi-case study examined individual teacher cases using a within-case analysis to create teachers’ profiles to illuminate contextual traits and elucidate …


It’S Getting Hot In Here, So Maintain Situational Awareness, Abby Zavadil May 2024

It’S Getting Hot In Here, So Maintain Situational Awareness, Abby Zavadil

Scientific Kenyon: The Neuroscience Edition

No abstract provided.


The Impact Of Death Anxiety On Counselors’-In-Training Efficacy With Substance Use Populations, Jason Rose May 2024

The Impact Of Death Anxiety On Counselors’-In-Training Efficacy With Substance Use Populations, Jason Rose

Dissertations

Death anxiety has been an unremitting agent of the human experience. The psychological dilemma posed by the awareness and forecasting of death can increase anxiety, thus affecting well-being through the compulsive desire or will to persist (Becker, 1973; Yalom, 1980). Such psychological armor can manifest in conscious and unconscious behaviors, thoughts, and emotions to which persons utilize psychological, social, and cultural defenses to manage anxiety (Becker, 1973; Solomon et al., 2015). Across all levels of counseling, there has been a deficiency in awareness and discussion of death-related fears within the therapeutic process (Lacocque & Loeb, 1988). Therefore, due to the …


Comparison Of Bayesian Versus Maximum Likelihood Estimation In The Case Of Unbalanced Panels With Count Data, Bryan Hudson May 2024

Comparison Of Bayesian Versus Maximum Likelihood Estimation In The Case Of Unbalanced Panels With Count Data, Bryan Hudson

Dissertations

Commonly in applied research settings, investigators wish to study counts of some event of interest over time, such as number of infections, or absences from school. However, in many cases, investigators may only have access to data sets in which measurements with individuals are not available at each measurement timepoint. A foundational statistical method for the study of panel data is generalized linear mixed effect modeling, which typically uses the maximum likelihood estimation (MLE) to estimate parameters. However, Bayesian estimation (BE) offers an alternative approach. In this simulation study, data were generated with varying sample sizes, proportions of missing data, …


Scientific Kenyon: Neuroscience Edition (Full Issue) May 2024

Scientific Kenyon: Neuroscience Edition (Full Issue)

Scientific Kenyon: The Neuroscience Edition

No abstract provided.


What Does Aaron Hernandez Have In Common With Your High Schooler?, Sam Lee May 2024

What Does Aaron Hernandez Have In Common With Your High Schooler?, Sam Lee

Scientific Kenyon: The Neuroscience Edition

No abstract provided.


Teaching Financial Econometrics To Students Converting To Finance, Stan Hurn, Peter C. B. Phillips, Vance Martin, Jun Yu May 2024

Teaching Financial Econometrics To Students Converting To Finance, Stan Hurn, Peter C. B. Phillips, Vance Martin, Jun Yu

Cowles Foundation Discussion Papers

Financial econometrics is a dynamic discipline that began to take on its present form around the turn of the century. Since then it has found a permanent position as a popular course sequence in both undergraduate and graduate teaching programs in economics, finance, and business schools. Because of the breadth of the subject’s foundations, its extensive coverage in applications and because these courses attract a wide range of students with accompanying interests and skill sets that cover diverse areas and technical capabilities, teaching financial econometrics presents many challenges to the university educator. This chapter addresses some of these challenges, provides …


Targeting Coenzyme A Biosynthesis For Antifungal Development., Jessica Regan May 2024

Targeting Coenzyme A Biosynthesis For Antifungal Development., Jessica Regan

Theses and Dissertations (ETD)

An estimated 1.5 million people die each year from invasive fungal infections (IFIs) involving dissemination to the deeper organs via the bloodstream, with estimated healthcare costs of over $7 billion in the U.S. alone. Collectively, several Candida species account for more than 75% of disseminated fungal infections in the U.S., with attributable mortality rates ranging 35-75%. Unfortunately, the prospect of curing these infections is limited by the modest efficacy of the available antifungal drugs: the azoles, echinocandins, and amphotericin B. Approximately one-third of patients with disseminated Candida infections are non-responsive to treatment with the azoles, and favorable response rates are …


Identifying Contributors To Acute Stroke Transfer Delays From Lower To Higher Level Stroke Centers, Jennifer Patterson May 2024

Identifying Contributors To Acute Stroke Transfer Delays From Lower To Higher Level Stroke Centers, Jennifer Patterson

Theses and Dissertations (ETD)

The intricate process of efficiently transferring patients within the healthcare setting has proven to be complex however, it is a critical component to ensure timely access to essential medical interventions. Navigating these complexities presents a multifaceted challenge that is not fully understood. For patients suffering a stroke, these transfer delays may render them ineligible for treatment and left with disabling disability. This collective work aims to identify contributors to delays in transfer from lower to higher levels of care in the acute stroke populations.

Three papers emerged from this thesis. First, a narrative review of the literature published between January …


Optimizing Adult Learner Success: Applying Random Forest Classifier In Higher Education Predictive Analytics, Emily Barnes, James Hutson, Karriem Perry May 2024

Optimizing Adult Learner Success: Applying Random Forest Classifier In Higher Education Predictive Analytics, Emily Barnes, James Hutson, Karriem Perry

Faculty Scholarship

This study examines the application of the Random Forest Classifier (RF) model in predicting academic success among adult learners in higher education. It focuses on evaluating the model's effectiveness using key statistical measures like accuracy, precision, recall, and F1 score across a comprehensive dataset from 2013–14 to 2021–22, which includes variables such as age, ethnicity, gender, Pell Grant eligibility, and academic performance metrics. The research highlights the RF model's capability to handle large datasets with varying data types and demonstrates its superiority over traditional regression models in predictive accuracy. Through an iterative process, the study refines the RF model to …


Composing From The Margins: The Breaking Of Writing Barriers, Empowering Voices & Broadening The Work Of Feminist Composition Studies, Jasmin Salgado May 2024

Composing From The Margins: The Breaking Of Writing Barriers, Empowering Voices & Broadening The Work Of Feminist Composition Studies, Jasmin Salgado

Electronic Theses, Projects, and Dissertations

The concept of identity politics within Composition Studies acknowledge how a writer’s social identity (race, gender, sexuality, disabilities, etc.) influences their writing style and shapes their language. Understanding the relationship between social identity and writing practices means recognizing the diverse perspectives writers bring to the writing classroom. In alignment with this perspective, feminist composition studies emphasize the importance of centering marginalized voices and creating inclusive learning environments where students can safely express their identities through writing. However, research reveals that diverse perspectives haven’t always been welcomed in academic spaces. Feminist compositionists unveil how discourse around writing conventions and language norms …


Mandated Reporters’ Knowledge And Reporting Of Child Abuse, Alexis Reilly Warye May 2024

Mandated Reporters’ Knowledge And Reporting Of Child Abuse, Alexis Reilly Warye

Electronic Theses, Projects, and Dissertations

Individuals working with children should have the ability to identify and report child abuse based off their knowledge as a mandated reporter. The purpose of this study is to assess the knowledge of individuals working with children on their ability to identify and report child abuse. The literature suggests that some mandated reporters lack adequate training and display little knowledge of what to do in a situation where a child shows signs of abuse. This study incorporates the Systems Theory Approach and the Psychosocial Development Theory.

This study uses a cross-sectional quantitative research design using an online questionnaire designed by …


Justice-Involved Students: Effects Of Using Support Services To Overcome Barriers, Gabby Walker, Sofia Alvarenga May 2024

Justice-Involved Students: Effects Of Using Support Services To Overcome Barriers, Gabby Walker, Sofia Alvarenga

Electronic Theses, Projects, and Dissertations

This study investigated formerly incarcerated students' perspectives on the effectiveness of re-entry programs in alleviating barriers to higher education. The study focused on six barriers: parole and probation, collateral consequences, admission, housing, and stigma, aiming to provide insights into program effectiveness. Using an exploratory, quantitative approach, data was collected through surveys distributed via social media and online platforms. Parole and probation were not perceived as significant barriers by participants. Challenges related to collateral consequences, such as limited access to housing and employment opportunities, were highlighted as barriers. Participants did not view recidivism as a significant obstacle to pursuing higher education. …