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Autologous Bone Marrow Mononuclear Cells To Treat Severe Traumatic Brain Injury In Children, Charles S Cox, David M Notrica, Jenifer Juranek, Jeffrey H Miller, Fabio Triolo, Steven Kosmach, Sean I Savitz, P David Adelson, Claudia Pedroza, Scott D Olson, Michael C Scott, Akshita Kumar, Benjamin M Aertker, Henry W Caplan, Margaret L Jackson, Brijesh S Gill, Robert A Hetz, Michael S Lavoie, Linda Ewing-Cobbs May 2024

Autologous Bone Marrow Mononuclear Cells To Treat Severe Traumatic Brain Injury In Children, Charles S Cox, David M Notrica, Jenifer Juranek, Jeffrey H Miller, Fabio Triolo, Steven Kosmach, Sean I Savitz, P David Adelson, Claudia Pedroza, Scott D Olson, Michael C Scott, Akshita Kumar, Benjamin M Aertker, Henry W Caplan, Margaret L Jackson, Brijesh S Gill, Robert A Hetz, Michael S Lavoie, Linda Ewing-Cobbs

Faculty, Staff and Student Publications

Autologous bone marrow mononuclear cells (BMMNCs) infused after severe traumatic brain injury have shown promise for treating the injury. We evaluated their impact in children, particularly their hypothesized ability to preserve the blood–brain barrier and diminish neuroinflammation, leading to structural CNS preservation with improved outcomes.

We performed a randomized, double-blind, placebo-sham-controlled Bayesian dose-escalation clinical trial at two children's hospitals in Houston, TX and Phoenix, AZ, USA (NCT01851083). Patients 5–17 years of age with severe traumatic brain injury (Glasgow Coma Scale score ≤ 8) were randomized to BMMNC or placebo (3:2). Bone marrow harvest, cell isolation and infusion were …


The Protection Of Legitimate Expectations In International Law, Halil Rahman Basaran May 2024

The Protection Of Legitimate Expectations In International Law, Halil Rahman Basaran

San Diego International Law Journal

The argument of this Article is that international law has still not reached a stage wherein the protection of legitimate expectations can become a general principle of law. In that respect, the most favorable terrain for the protection of legitimate expectations, namely, inter-state negotiations, still largely remains outside international law. In pursuing this argument, this Article first examines the notions of national sovereignty, legal institution and inter-state boundaries. This paper then looks at the notion of general principles of law and highlights the principle of equity. Finally, the Article discusses the Bolivia v. Chile case and places international investment law …


Outsmarting Smart Devices: Preparing For Ai Liability Risks And Regulations, Kathryn Bosman Cote May 2024

Outsmarting Smart Devices: Preparing For Ai Liability Risks And Regulations, Kathryn Bosman Cote

San Diego International Law Journal

As AI technology continues to advance rapidly, establishing a new model for AI regulation will be crucial to protect both companies and consumers. The U.S. must consider consumer safety as well as innovation-conducive policies when assigning liability to AI. By using EU regulatory guidance as a starting point, this paper argues that a multi-tiered liability scheme coupled with a Uniform AI ethical framework and the creation of an independent AI regulatory agency would aid the U.S. in striking the right balance to effectively combat the risks posed by AI and IoT.


International Conformity To The Standard Minimum Age Of Criminal Responsibility: Comparing The Minimum Age Of Criminal Responsibility To The Minimum Legal Age Of Marriage, Malea Casillas May 2024

International Conformity To The Standard Minimum Age Of Criminal Responsibility: Comparing The Minimum Age Of Criminal Responsibility To The Minimum Legal Age Of Marriage, Malea Casillas

San Diego International Law Journal

As this data shows, countries across the globe, irrespective of culture, comply with and uphold the international MLAM. In contrast, they simultaneously fail to agree to the international MACR. The universal conformity with the international MLAM demonstrates that countries understand the negative consequences of marriage at a young age and care to protect children against child marriage. However, the even lower MACRs across the globe indicate that most of our world values prosecution over protection and likely sees offender first and child second.

This Comment will argue that MACR and MLAM should be recognized as similar legal concepts that are …


Free Speech Censorship In The Philippines: The Push To Decriminalize Libel, Carter Cordura May 2024

Free Speech Censorship In The Philippines: The Push To Decriminalize Libel, Carter Cordura

San Diego International Law Journal

Philippine criminal libel law is unjustly being used to suppress and censor the media and press; libel should be decriminalized and redefined to uphold the ideals of due process and freedom of expression enumerated in the Philippine Constitution.

This Comment takes a deep dive into Philippine libel law and argues for its decriminalization and redefining from an international perspective.


Thinking In Relation To Method: Metaphilosophical Reflections On Philosophy's Orientation To Methodology, Morgan Elbot May 2024

Thinking In Relation To Method: Metaphilosophical Reflections On Philosophy's Orientation To Methodology, Morgan Elbot

Electronic Theses and Dissertations Archive

This portfolio style dissertation examines the relationship between philosophy and method from distinct traditions in continental philosophy. The first chapter presents an exegetical analysis of Gilles Deleuze and Felix Guattari’s metaphilosophical account of concept creation and Deleuze’s critique of method in the context of the dogmatic image of thought. The analysis explores the various facets and theoretical influences of his critique in order to elucidate the parameters of his rejection of method as part of the creative activity that defines philosophical practice. Through identifying exceptions that qualify the extent of his critique, the chapter concludes by calling for a new …


Short-Term Benefits From Manual Therapy As An Adjunct Treatment For Persistent Postural-Perceptual Dizziness Symptoms: A Preliminary Prospective Case Series, Brent A. Harper, Larry Steinbeck May 2024

Short-Term Benefits From Manual Therapy As An Adjunct Treatment For Persistent Postural-Perceptual Dizziness Symptoms: A Preliminary Prospective Case Series, Brent A. Harper, Larry Steinbeck

Physical Therapy Faculty Articles and Research

Persistent dizziness and balance deficits are common, often with unknown etiology. Persistent Postural-Perceptual Dizziness (3PD) is a relatively new diagnosis with symptoms that may include dizziness, unsteadiness, or non-vertiginous dizziness and be persistent the majority of time over a minimum of 90 days. The purpose of this case series was to investigate short-term outcomes of reducing dizziness symptoms using a manual therapy intervention focused on restoring mobility in the fascia using a pragmatically applied biomechanical approach, the Fascial Manipulation® method (FM®), in patients with 3PD. The preliminary prospective case series consisted of twelve (n = 12) patients …


Language Enrollment In Higher Education: Exploring Social Psychological Factors In Spanish Language Programs With Advanced Learners, David Antonio Balmaceda Marenco May 2024

Language Enrollment In Higher Education: Exploring Social Psychological Factors In Spanish Language Programs With Advanced Learners, David Antonio Balmaceda Marenco

Arts & Sciences Graduate Student Theses and Dissertations

Amidst waning enrollments in U.S. university Spanish courses, particularly at advanced levels, this three-study dissertation addresses the pronounced gender imbalances, delving into the sociopsychological dynamics such as beliefs, attitudes, motivation, and gender in the context of the specific language learning domains of listening, speaking, reading, and writing. Positioned at a crucial juncture—often seen as a gateway to more advanced courses—the research uncovers the nuanced beliefs of learners about these foundational skills. Employing a blend of quantitative and mixed-methods designs, the studies emphasize the pivotal role of reading in advanced university Spanish coursework. Findings from the initial two studies, encapsulating diverse …


Design, Synthesis, Self-Assembly, And Applications Of Functional Bottlebrush Architectures Through Ring-Opening Metathesis Polymerization, Yipei Zhang May 2024

Design, Synthesis, Self-Assembly, And Applications Of Functional Bottlebrush Architectures Through Ring-Opening Metathesis Polymerization, Yipei Zhang

Arts & Sciences Graduate Student Theses and Dissertations

Shear-thinning hydrogels are a class of materials with unique rheological properties that enable them to undergo a reversible reduction in viscosity under shear stress, which allows for easy injection. The injectability of shear-thinning hydrogels is particularly important when considering their use in biomedical applications, such as drug delivery, tissue engineering, and wound healing. However, before advancing to these applications, it is crucial to evaluate the “injectability” of new shear-thinning hydrogels to avoid clogging of the needle for injection. Injectability is typically associated with determining suitable viscosity, storage/loss moduli, and other factors, such as injection force (e.g., needle length and gauge …


Community College Women’S Perceptions Of Hpv And Cervical Cancer, Odella Dianne Hagan May 2024

Community College Women’S Perceptions Of Hpv And Cervical Cancer, Odella Dianne Hagan

Walden Dissertations and Doctoral Studies

Community college women do not obtain the HPV vaccine at the same rate as university women. The aim of this study was to discover the perceptions of community college women in relation to the human papillomavirus (HPV) and associated cancers, the perceived barriers and benefits of obtaining the HPV vaccination, and how health behavior decisions may be impacted by self-concept. A qualitative research design incorporating thematic analytic was used to analyze interviews whose questions were specifically guided by the health belief model. Student volunteers aged 18 to 45 years were recruited from a large urban community college. An inductive thematic …


Parental Knowledge Of Signs, Symptoms, And Risk Factors Associated With Sudden Cardiac Arrest In Adolescent Athletes, Lisa A. Lattera-Hughes May 2024

Parental Knowledge Of Signs, Symptoms, And Risk Factors Associated With Sudden Cardiac Arrest In Adolescent Athletes, Lisa A. Lattera-Hughes

Walden Dissertations and Doctoral Studies

Exercise is associated with unmasking underlying cardiac disorders and increasing an athlete’s risk for experiencing a sudden cardiac arrest (SCA) event during sports. Parental knowledge is an important component of health education in relation to the future of their child’s health. The purpose of this quantitative research study was to assess the relationship between parental knowledge about warning signs, symptoms, and risk factors associated with SCA in adolescent athletes and parental willingness to participate in an educational intervention to learn about SCA. The theoretical framework was based on Nutbeam’s conceptual model of health literacy. Eightyone parents whose adolescent children participated …


Probation And Pre-Trial Officers' Perspectives On The Impact Of Maternal Incarceration On Children, Shaniqua Anderson May 2024

Probation And Pre-Trial Officers' Perspectives On The Impact Of Maternal Incarceration On Children, Shaniqua Anderson

Walden Dissertations and Doctoral Studies

Because of the mass incarceration of women, maternal incarceration has become a phenomenon within itself. This phenomenon has led to an increase in Black children with an incarcerated mother; however, there is a lack of information about how the cycle of the mass incarceration of Black women is perceived on the community supervision level. The purpose of this qualitative phenomenological study was to better understand probation and pre-trial officers’ perceptions of how the maternal incarceration of Black women impacts Black children. Three research questions explored how participants viewed the impact of maternal incarceration on Black children, recidivism, and positive reentry. …


A Realist Interpretation Of Unitarity In Quantum Gravity, Indrajit Sen, Stephon Alexander, Justin Dressel May 2024

A Realist Interpretation Of Unitarity In Quantum Gravity, Indrajit Sen, Stephon Alexander, Justin Dressel

Mathematics, Physics, and Computer Science Faculty Articles and Research

Unitarity is a difficult concept to implement in canonical quantum gravity because of state non-normalisability and the problem of time. We take a realist approach based on pilot-wave theory to address this issue in the Ashtekar formulation of the Wheeler–DeWitt equation. We use the postulate of a definite configuration in the theory to define a global time for the gravitational-fermionic system recently discussed in Alexander et al (2022 Phys. Rev. D 106 106012), by parameterising a variation of a Weyl-spinor that depends on the Kodama state. The total Hamiltonian constraint yields a time-dependent Schrodinger equation, without semi-classical approximations, which we …


Quantification Of Surface Layer Turbulence Using Sensible Heat Values From Energy Balance Versus Aerodynamic Methods, Steven T. Fiorino, Yogendra Raut, Jaclyn Schmidt, Laura Slabaugh, Blaine Fourman, Jack E. Mccrae, Benjamin C. Wilson, Santasri R. Bose-Pillai May 2024

Quantification Of Surface Layer Turbulence Using Sensible Heat Values From Energy Balance Versus Aerodynamic Methods, Steven T. Fiorino, Yogendra Raut, Jaclyn Schmidt, Laura Slabaugh, Blaine Fourman, Jack E. Mccrae, Benjamin C. Wilson, Santasri R. Bose-Pillai

Faculty Publications

Surface layer optical turbulence values in the form of the refractive index structure function C_n^2 are often calculated from surface layer temperature, moisture, and wind characteristics and compared to measurements from sonic anemometers, differential temperature sensors, and imaging systems. A key derived component needed in the surface layer turbulence calculations is the sensible heat value. Typically, the sensible heat is calculated using the bulk aerodynamic method that assumes a certain surface roughness and a friction velocity that approximates the turbulence drag on temperature and moisture mixing from the change in the average surface layer vertical wind velocity. These assumptions/approximations generally …


Strategies To Rapidly Decommission Information Technology Satellites To Prevent Low Earth Orbit Space Debris, Nathaniel Richard Juarez May 2024

Strategies To Rapidly Decommission Information Technology Satellites To Prevent Low Earth Orbit Space Debris, Nathaniel Richard Juarez

Walden Dissertations and Doctoral Studies

Information technology (IT) assets rely heavily on satellites in space, with most of them in low Earth orbit (LEO). There is a growing threat towards IT satellites in LEO and cybersecurity professionals must implement proactive measures through policy reform and hardening procedures to prevent cyberattacks. The Kessler syndrome will become existent if satellites start crashing into each other or space debris orbiting the Earth. Grounded in the integrated system theory of information security management, the purpose of this qualitative pragmatic inquiry was to explore strategies IT satellite managers in the space industry use to properly harden and rapidly decommission satellites …


Effective Strategies To Reduce Registered Nurse Turnover In Hospitals, Adrienne Cozart May 2024

Effective Strategies To Reduce Registered Nurse Turnover In Hospitals, Adrienne Cozart

Walden Dissertations and Doctoral Studies

Registered nurse (RN) turnover remains a problem for many healthcare organizations. Hospital nurse leaders are concerned with RN turnover because of its negative effect on the profitability of hospitals. Grounded in transformational leadership theory, the purpose of this qualitative multiple case study was to explore the strategies that hospital nurse leaders use to reduce RN turnover. The participants were four hospital nurse leaders who reduced RN turnover in two hospitals in Texas. Data were collected using semistructured interviews and a review of organizational documentation. Thematic analysis of the data resulted in three themes: turnover reduction strategies, barriers or challenges to …


Dual Modes Of Dopamine Underly Distinct Facets Of Impulsive Actions, Tzvia Pinkhasov May 2024

Dual Modes Of Dopamine Underly Distinct Facets Of Impulsive Actions, Tzvia Pinkhasov

Arts & Sciences Graduate Student Theses and Dissertations

During the pursuit of basic needs, animals sometimes fail to suppress actions that are maladaptive and counterproductive to their survival. In humans, these actions are often called impulsive because they can incur negative consequences. Impulsivity is ubiquitous across psychiatric disorders and related to debilitating outcomes such as substance abuse, crime and suicidality. Despite its risks, a lack of a neural mechanism understanding of impulsive actions impedes the development of effective treatments.In this dissertation, I set out to bridge the knowledge gained from the parallel fields of neuropsychopharmacology, experimental psychology, and systems neuroscience to uncover neural mechanisms of impulsive actions. Clinicians …


Evaluation And Education Of Enhanced Recovery After Surgery Protocols For Total Knee Arthroplasty, Lauren Hunt, Jessica Prost May 2024

Evaluation And Education Of Enhanced Recovery After Surgery Protocols For Total Knee Arthroplasty, Lauren Hunt, Jessica Prost

Doctor of Nursing Practice Projects

Enhanced recovery after surgery (ERAS) utilizes a multimodal, multidisciplinary perioperative protocol to minimize hospital length of stay, surgical complications, readmissions, and patient hospital costs (Frassanito et al., 2020). The protocols were initially established for abdominal and colorectal surgical patients; however, ERAS protocols are now widely used in other areas, including orthopedic surgery (Kaye et al., 2019). To achieve the maximum benefits, ERAS protocols must contain preoperative, intraoperative, and postoperative components. A rural critical access hospital in Eastern Illinois, Crawford Memorial Hospital, serves numerous patients requiring total knee arthroplasties (TKA). While the providers utilize some aspects of ERAS protocols for these …


Introduction Of Osteoporosis Screening Within Orthopedic Clinics, Kimberly Dray May 2024

Introduction Of Osteoporosis Screening Within Orthopedic Clinics, Kimberly Dray

Doctor of Nursing Practice Projects

Abstract

Osteoporosis affects millions of Americans, causing life life-altering medical issues and an economic burden estimated to be over 17 billion dollars. Primary care providers are responsible for screening and early detection of osteoporosis; however, gaps have been identified. Orthopedic surgeons can screen during clinic visits to help close the gap. The purpose of this project was to introduce the usage of a screening tool in a large orthopedic clinic to improve detection. Participants were provided with education regarding osteoporosis and the screening tool with continued support throughout the 8-week study. Using the Simplified Calculated Osteoporosis Risk Estimation (SCORE) tool, …


The Effect Of Preparation On The Quality Of Sign Language Interpretation, Hólmfríður Thóroddsdóttir, Karen Rut Gísladóttir May 2024

The Effect Of Preparation On The Quality Of Sign Language Interpretation, Hólmfríður Thóroddsdóttir, Karen Rut Gísladóttir

Journal of Interpretation

This article discusses the effect of preparation on the cognitive load of sign language interpreters and its relationship to the quality of sign language interpretation. Participants were all sign language interpreters working in Iceland. The data collected were both qualitative and quantitative, i.e. interviews, a questionnaire in connection with a special interpreting project and a specially designed interpretation test. The test was held to obtain statistical information on the effects of preparation on sign language interpretation and to get feedback from the interpreters themselves about what they consider important to prepare.

The results of the study show that preparation both …


Signed Language Interpreter Education Programs In North America: A Descriptive Study, Len Roberson, Sherry Shaw May 2024

Signed Language Interpreter Education Programs In North America: A Descriptive Study, Len Roberson, Sherry Shaw

Journal of Interpretation

The objective of this study is to provide interpreter education faculty, university administrators, accrediting bodies, stakeholders, interpreters, and students (current or prospective) a descriptive snapshot-in-time of interpreter education curriculum and programs in North America. This study expands upon work done in the late 1987-1990 and 2007-2009 to capture a descriptive snapshot-in-time of the preparation of signed language interpreters. Researchers anticipated learning how programs align their curricula with CCIE accreditation standards (whether they are accredited or not), how two- and four-year programs (including Canada) allocate faculty time and resources, and how student characteristics and support systems differ among programs. This study …


The Social Experiment: How The First Amendment Influences Private Social Media Companies, Collyn J. Kim May 2024

The Social Experiment: How The First Amendment Influences Private Social Media Companies, Collyn J. Kim

Helms School of Government Undergraduate Law Review

Social media has become one of the biggest mediums by which people communicate, socialize, and interact with each other. People follow political figures, cultural icons, and news outlets, among others, to gain knowledge on current events or the hot topic of the day. Many users, regardless of the platform, use their medium of choice to speak their own opinions and comment on the world’s issues. From prime ministers to popular memes, social media is a never-ending timeline of speech. With the constant speech and expression exhibited on social media, two important questions must be asked. First, does the First Amendment …


Tts (Text To Speech) Adapter For Computer Displays, Hp Inc May 2024

Tts (Text To Speech) Adapter For Computer Displays, Hp Inc

Defensive Publications Series

This disclosure relates to the field of computer displays (monitors) with application of audio components to better meet accessibility standards.


Vol.51 N.41 May 2nd 2024, Voice Media Ventures May 2024

Vol.51 N.41 May 2nd 2024, Voice Media Ventures

Black Voice News

No abstract provided.


A Professional Series: Servant Leadr, Jeremy P. Todd May 2024

A Professional Series: Servant Leadr, Jeremy P. Todd

Morehead State Theses and Dissertations

A capstone submitted in partial fulfillment of the requirements for the degree of Doctor of Education in the Ernst and Sara Lane Volgenau College of Education at Morehead State University by Jeremy Todd on May 2, 2024.


Uncharted Territory: Researching The Effect Of Implicit Bias On The Political Attitudes Of Black Participants, Briona Young May 2024

Uncharted Territory: Researching The Effect Of Implicit Bias On The Political Attitudes Of Black Participants, Briona Young

Honors College Theses

Extant research suggests that implicit bias can predict behavior such as voting, policy preferences, and assessment of government performance (Pérez 2010). Yet, research on implicit bias has largely excluded people of color and differences in gender, leaving a wide gap in our understanding of implicit bias and its effects on society (Assari 2018: Orey 2013). In this study, I research implicit bias within the Black community and test its effects on political attitudes. I administered Harvard’s Implicit Association Test (IAT) and a survey to measure levels of implicit bias and subsequently race-related policy attitudes. I expect to find that the …


Software Reliability Model Estimation For An Indeterministic Crime Cluster Through Reinforcement Learning, Dileep Kumar Kadali, R.N.V. Jagan Mohan, M. Chandra Naik May 2024

Software Reliability Model Estimation For An Indeterministic Crime Cluster Through Reinforcement Learning, Dileep Kumar Kadali, R.N.V. Jagan Mohan, M. Chandra Naik

Neutrosophic Systems with Applications

The software reliability model estimates the probability of data failure in a specific environment, significantly impacting reliability and trustworthiness. The paper study focuses on cluster crime data, i.e., indeterministic in Neutrosophic Logic, using a software reliability model. The study utilizes reinforcement learning, Neutrosophic logic, and non-homogeneous Poisson process crime data to estimate indeterministic cluster data in crime. The "Non-homogeneous Poisson Process with Neutrosophic Logic" technique performs well in evaluating and deterring crime based on crime data analysis. The crime cluster involving offenders correctly classified as failure to accomplish does better than uncertain cluster reliability estimation with least squares and logistic …


Implementation Of A Doula-Supported Postpartum Wellness Toolkit In A Black Community-Based Maternal Wellness Program, Janice Luethje, Leslie Torres May 2024

Implementation Of A Doula-Supported Postpartum Wellness Toolkit In A Black Community-Based Maternal Wellness Program, Janice Luethje, Leslie Torres

Doctor of Nursing Practice Projects: College of Nursing

Objective: The objective of this project was to expand the areas of focus within a maternal wellness program at a Black community center and to evaluate the satisfaction levels of the doulas who utilized the material during postpartum home visits. The toolkit covers a range of postpartum topics in the areas of nutrition, exercise, sexual health, mindfulness, and social support as well as a postpartum mental health screening tool.

Design: This quality improvement project included three distinct phases: The pre-implementation phase, the implementation phase, and the post-implementation phase.

Setting: The project location was a Black community center in Lincoln, Nebraska. …


Implementing A Standardized Protocol For Early Detection Of Undiagnosed Hypertension Patients, Jenscena Hansen, Chris Bell May 2024

Implementing A Standardized Protocol For Early Detection Of Undiagnosed Hypertension Patients, Jenscena Hansen, Chris Bell

Doctor of Nursing Practice Projects: College of Nursing

Introduction: Hypertension is a preventable disease that frequently goes unrecognized and undertreated. Early diagnosis can prevent further comorbidities such as heart disease, stroke, and chronic kidney disease. Implementation of this protocol aims to decrease the number of patients with undiagnosed hypertension and increase the identification of patients with elevated blood pressure who did not have a pre-existing diagnosis of hypertension. The goal of implementing a standardized protocol would help eliminate the number of patients who go undiagnosed.

Methods: This quality improvement design had clinical staff flag patients with elevated blood pressure. Identified patients without a diagnosis of hypertension were educated …


Engineering Education In The Age Of Ai: Analysis Of The Impact Of Chatbots On Learning In Engineering, Flor A. Bravo, Juan M. Cruz Bohorquez May 2024

Engineering Education In The Age Of Ai: Analysis Of The Impact Of Chatbots On Learning In Engineering, Flor A. Bravo, Juan M. Cruz Bohorquez

Henry M. Rowan College of Engineering Departmental Research

The purpose of this paper is to explore the influence of using AI chatbots on learning within the context of engineering education. We framed this study on the principles of how learning works in order to describe the contributions and challenges of AI chatbots in five categories: (1) facilitating the acquisition, completion, or activation of prior knowledge and helping organize knowledge and making connections; (2) enhancing student motivation to learn; (3) fostering self-directed learning and the acquisition, practice, and application of the skills and knowledge they acquire; (4) supporting goal-directed practice and feedback; and (5) addressing student diversity and creating …