Digital Commons Network^™

Evaluation Of The Efficiency Of Muscle-Specific Promoters To Express Non-Endogenous Proteins In Skeletal Muscle, Gabrielle Bulliard, Made Harumi Padmaswari, Christopher E. Nelson

Biomedical Engineering Undergraduate Honors Theses

Gene therapies are emerging as powerful tools for treating genetic diseases and cancers, offering the potential for a permanent cure. Hemophilia B, affecting approximately 6,000 men in the U.S., results from a deficiency in coagulation factor IX protein (FIX), which is crucial for blood clotting. A substantial portion of patients, over 40%, suffer from severe hemophilia B, experiencing spontaneous, prolonged bleeding. Current prophylactic treatments involve frequent coagulation factor infusions, yet a curative approach would alleviate this burden. Gene editing technologies like CRISPR-Cas systems show promise for correcting genetic mutations, but the diverse nature of factor IX gene (F9) …

Safety Analysis In Ap-1000 Nuclear Power Plant Against Primary Loop Coolant Pump And Fuel Failures, Fabiano Gibson Daud Thulu, Hailemichael Guadie Mengsitu, Chifundo Tenthani, Paul Stone Macheso

International Journal of Nuclear Security

This study focused on the best-estimated thermal-hydraulic calculations performed regarding the AP-1000 nuclear power plant (NPP) under primary coolant loop pump and fuel failures. Primary coolant pump and fuel failure transients are important design-basis accidents in NPP safety assessments. This work examined the primary reactor’s safety margins of fuel and cladding peak temperature, primary and secondary loop pressure, hydrogen formation, and primary and secondary flow rates.The Adaptive System Thermal-Hydraulics program was used in the simulation and event progression analysis. The results showed that the peak fuel surface temperature was kept below the licensing design limit. No observation of corium was …

Using The Johns Hopkins Mobility Goal Calculator To Improve Functional Outcomes During Inpatient Stays And After Discharge, Thomas Badger Bsn, Rn, Katherine Bower Bsn, Rn, Becky Radolf Msn, Rn

Nurse Residency

Do adult hospital inpatients achieve pre-admission baseline functionality with higher frequency using the Johns Hopkins Mobility Goal Calculator (JH-MGC) versus the standard clinical approaches to mobility?

The Banner - V. 159, No. 5 - (May 2024), Christian Reformed Church In North America

The Banner

No abstract provided.

The Myth Of Dna Trade Secrecy, Jacob S. Sherkow

UC Law Journal

Are DNA sequences subject to trade secrecy protection? At least three decades of scholarship has assumed so even while there is no explicit statutory authority directly on point and very few reported decisions in the area. And yet, an investigation into the elements of trade secrecy law— read in light of rapid advances in DNA and genomic sequencing—suggests the answer is probably, no. Those advances include the rise of cheap, accurate, easy, fast, and readily available DNA sequencing services, including the recent availability of whole human genome sequencing for less than a monthly cell phone bill. This cuts against some …

Relationships, Species Boundaries, And Speciation Of Piper Section Enckea, Cara Jean Hastings

Boise State University Theses and Dissertations

Species are fundamental biological units but defining what constitutes a species has been debated by biologists, philosophers, and other scholars. Our concept of what constitutes a species has evolved over time, reflecting progress and advances in technology and types of data available as well as increased understanding of the complexity of the speciation process. To understand how extant species evolved, it is useful to evaluate their relationships using molecular data in a phylogenetic framework. By pairing phylogenetic data with other types of data including morphological and fossil data as well as topographical and climatic history, we can gain understanding of …

Traffic Sign Extraction From Mobile Lidar Point Cloud, Yushin Ahn, Riadh Munjy, Ziyuan Li

Mineta Transportation Institute

The extraction of traffic signs from Mobile Light Detection and Ranging (LiDAR) point cloud data has become a focal point in transportation research due to the increasing integration of LiDAR technologies. LiDAR, a remote sensing technology, captures detailed three-dimensional point cloud data, offering a comprehensive view of the surrounding environment. Mobile LiDAR systems mounted on vehicles enable efficient data collection, particularly for large-scale road networks. This study aims to develop and refine techniques for extracting traffic signs from Mobile LiDAR point cloud data, essential for enhancing road safety, navigation systems, and intelligent transportation solutions. By leveraging LiDAR technology, new possibilities …

New York City Corporation Counsel Sylvia O. Hinds-Radix Named Keynote Speaker At New York Law School’S 132nd Commencement, New York Law School

NYLS Community News

No abstract provided.

Impact Of Leadership In Project Management, Ian Wegh

Information Systems Undergraduate Honors Theses

Today’s business environment demands effective project management for enterprises to meet their goals and continue to be innovative. Inherently, this also means that project managers must have strong leadership skills. Project management provides a framework of techniques that provides a symbiotic relationship between both the framework and the leader. The idea behind project management is to complete objectives efficiently within a certain time period given a restricted number of resources. This means project management is a process of principles, tools, and methodologies used to effectively manage a team through the System Development Life Cycle. The System Development Life Cycle (SDLC) …

Investigating The Integration Of Demand Distribution Modeling In Supply Chain Simulation, Marshal Ray

Industrial Engineering Undergraduate Honors Theses

This research presents a methodology for modeling the amount of demand and the time intervals between demands within a complex supply chain simulation program. The research outlines the approach, incorporating factor analysis and consolidation techniques, with a focus on using Random Forest modeling for factor importance identification. The results section covers demand quantity modeling utilizing both continuous and discrete empirical approaches, accompanied by considerations for outlier and overall distributions. While using these modeling techniques, P-P plots and KS-Statistics were employed to assess the goodness of fit, as a way to make recommendations for these models. The time between demand modeling …

Genomic Characterization Of Enterococcus Spp Infecting Chicken Embryo, Aishat Olaoluwa Lawal

Graduate Theses and Dissertations

Chicken embryo mortality has been attributed to bacterial infections and can lead to a decline in hatchability, posing potential losses in the broiler industry. This study aims to investigate the vertical transmission of specific bacterial pathogens from breeder hens to subsequent broiler flocks through MGEs and their association with host specificity. In our sampling of 360 eggs from a broiler flock, we isolated various Enterococcus species, including E. gallinarum and E. faecalis, from incubated egg yolks or aborted embryos. E. avium was found in unincubated bad yolks. Other species like Streptococcus, Lactobacillus, and Bacillus were observed but presumed to be …

Perceptions Of School-Based Agricultural Education Teachers Toward Promoting Agricultural Education Teaching As A Career, Emmanuel Kwadwo Sekyere

Graduate Theses and Dissertations

School-based agricultural education has experienced a scarcity of qualified teachers over the years. To reduce the prevalence of school-based agricultural teacher shortages, research has led to the adoption of several approaches in schools across the country. The purpose of this study was to examine the perceptions of school-based agricultural education teachers toward promoting agricultural teaching as a career. The theoretical framework for this research was based on the Theory of Planned Behavior. The research objectives were to determine the perceived importance of career promotion activities, the frequency of career promotion activities, the perceived job satisfaction of SBAE teachers, and the …

Describing Benefits, Challenges, And Barriers Of Offering Adolescent Programs At Public Gardens In The United States, Hiliary Rodgers

Graduate Theses and Dissertations

Research shows a lack of educational programs for the adolescent audience at public gardens in the United States. Along with benefits that adolescent programs create for the institutions that offer them, there are also challenges associated with designing programs for this specific audience, and barriers preventing public gardens from offering them. There is little research related to adolescent programs at public gardens in the United States, aside from a 2010 study by Purcell et al. that explored the benefits, challenges, and barriers of adolescent programs. The current study aimed to determine the prevalence of adolescent programs at public gardens in …

The Role Of The Patterning Cascade Model In Human Mandibular Premolar Variation, Molly Militello

Graduate Theses and Dissertations

Human mandibular premolars represent a morphologically transitional tooth class, possessing a relatively caniniform third premolar (P3) and a more molariform fourth premolar (P4). Marked variation in cusp height and lingual cusp number are characteristics unique to these postcanine teeth. The aim of this study is to determine if human premolar variation aligns with predictions outlined by the patterning cascade model (PCM). The PCM posits that tooth size and enamel knot spacing/surrounding inhibitory fields (approximated by cusp tip positioning) play a role in determining ultimate crown morphology, providing a predictive framework for examining crown variation within and between individuals. While there …

Cam And Design For Manufacturing: Developing A Project-Based Learning Course, Stephen Pierson

Mechanical Engineering Undergraduate Honors Theses

To effectively serve student career success, mechanical engineering programs must teach students how to account for manufacturing considerations in design. Despite this, manufacturing education is a glaring area of need in current engineering curricula. In fact, basic manufacturing knowledge is one of the only hard skills consistently ranked as one of the greatest weaknesses of mechanical engineering hires in surveys of industrial employers over the last few decades. Without radically changing departmental curriculum to include more emphasis on design-build projects, one solution to combat this is to incubate a lab course in mechanical engineering programs in which undergraduates would practice …

Cmd: Co-Analyzed Iot Malware Detection And Forensics Via Network And Hardware Domains, Ziming Zhao, Zhaoxuan Li, Jiongchi Yu, Fan Zhang, Xiaofei Xie, Haitao Xu, Binbin Chen

Research Collection School Of Computing and Information Systems

With the widespread use of Internet of Things (IoT) devices, malware detection has become a hot spot for both academic and industrial communities. Existing approaches can be roughly categorized into network-side and host-side. However, existing network-side methods are difficult to capture contextual semantics from cross-source traffic, and previous host-side methods could be adversary-perceived and expose risks for tampering. More importantly, a single perspective cannot comprehensively track the multi-stage lifecycle of IoT malware. In this paper, we present CMD, a co-analyzed IoT malware detection and forensics system by combining hardware and network domains. For the network part, CMD proposes a tailored …

Enhancing Visual Grounding In Vision-Language Pre-Training With Position-Guided Text Prompts, Alex Jinpeng Wang, Pan Zhou, Mike Zheng Shou, Shuicheng Yan

Research Collection School Of Computing and Information Systems

Vision-Language Pre-Training (VLP) has demonstrated remarkable potential in aligning image and text pairs, paving the way for a wide range of cross-modal learning tasks. Nevertheless, we have observed that VLP models often fall short in terms of visual grounding and localization capabilities, which are crucial for many downstream tasks, such as visual reasoning. In response, we introduce a novel Position-guided Text Prompt ( PTP ) paradigm to bolster the visual grounding abilities of cross-modal models trained with VLP. In the VLP phase, PTP divides an image into N x N blocks and employs a widely-used object detector to identify objects …

Vibmilk: Non-Intrusive Milk Spoilage Detection Via Smartphone Vibration, Yuezhong Wu, Wei Song, Yanxiang Wang, Dong Ma, Weitao Xu, Mahbub Hassan, Wen Hu

Research Collection School Of Computing and Information Systems

Quantifying the chemical process of milk spoilage is challenging due to the need for bulky, expensive equipment that is not user-friendly for milk producers or customers. This lack of a convenient and accurate milk spoilage detection system can cause two significant issues. First, people who consume spoiled milk may experience serious health problems. Secondly, milk manufacturers typically provide a “best before” date to indicate freshness, but this date only shows the highest quality of the milk, not the last day it can be safely consumed, leading to significant milk waste. A practical and efficient solution to this problem is proposed …

The Impact Of Avatar Completeness On Embodiment And The Detectability Of Hand Redirection In Virtual Reality, Martin Feick, Andre Zenner, Simon Seibert, Anthony Tang, Antonio Krüger

Research Collection School Of Computing and Information Systems

To enhance interactions in VR, many techniques introduce offsets between the virtual and real-world position of users’ hands. Nevertheless, such hand redirection (HR) techniques are only effective as long as they go unnoticed by users—not disrupting the VR experience. While several studies consider how much unnoticeable redirection can be applied, these focus on mid-air floating hands that are disconnected from users’ bodies. Increasingly, VR avatars are embodied as being directly connected with the user’s body, which provide more visual cue anchoring, and may therefore reduce the unnoticeable redirection threshold. In this work, we studied more complete avatars and their effect …

Ce 590 Syllabus: Addiction Counseling: Practicum, Mitch Moore

Counselor Education Syllabi

This is a Counselor Education practium for addiction counseling.

Practiced Peril: The Flawed Role Of Experience In Accidental Death Determinations, Casey M. Corvino

Connecticut Law Review

Words often carry an intuitive meaning that defies explicit definition. While this vagueness typically poses no issue in our daily lives, it presents distinct challenges within the legal realm where words and their definitions wield the power to influence the course of justice. One abstract concept is notoriously elusive: what is an accident? Despite the apparent simplicity of identifying what is commonly understood implicitly, there are inherent challenges in “giving substance to a concept which is largely intuitive.”

The Wickman framework was crafted to navigate these challenges, recognizing that an insured’s background, experience, and skill in a particular activity may …

Ensuring Climate Litigants’ Standing: Insights From National And International Climate Litigation, Florence T.B. Simon

Connecticut Law Review

In March 2023, the Intergovernmental Panel on Climate Change (IPCC) released its Sixth Assessment Report and confirmed unequivocally that human activities are the cause of climate change. Greenhouse gas emissions over the next few years are capable of causing irreversible and catastrophic damage to our planet. Catalyst litigation plays an important role in tackling climate change by prodding governments to assume a role in implementing adaptation and mitigation measures. Despite the extreme consequences that climate change will have on humanity, jurisdictional issues—such as standing—impose considerable hurdles for climate litigants. And these hurdles ultimately keep plaintiffs from obtaining a ruling, or …

Train Or Restrain? Using International Perspectives To Inform The American Fair Use Analysis Of Copyright In Generative Artificial Intelligence Training, Serena Lightstone

Northwestern Journal of International Law & Business

The rise of generative artificial intelligence (“AI”) has brought questions regarding the permissibility of using copyrighted materials in training generative AI systems around the globe. This article examines whether such use constitutes infringement under the American fair use doctrine, drawing insights from the regulatory approaches of the European Union (EU) and Japan.

Ultimately, this article advocates for United States courts to recognize the permissibility of using copyrighted materials in training generative AI models, rejecting the EU’s rights-holder-centric approach, and going beyond Japan’s limited-permissibility solution. Through a detailed four-factor fair use analysis, this article demonstrates that training generative AI on copyrighted …

Future Market Blueprints: Harnessing Artificial Intelligence In A World Wired For Wonder, David Temprano

Northwestern Journal of International Law & Business

George, Jane, and the gang from The Jetsons promised us the dream to soar with flying cars. Well, we move forward with self-driving cars. Robot maids? Well, we got a handy dandy Roomba. The Turn-off-the-Boss Button? Well, we have screen share toggling and the mute button. What each of these examples has in common is artificial intelligence (AI). According to some estimates, AI and its innovation have the potential to boost the global economy by trillions of dollars a year, revolutionizing society in the process. In this process comes progress, but also worry and questions, law and intervention, along with …

Exploring Asynchronous Pronunciation Training Through Context-Aware Pronunciation Applications, Claire L. Schweikert

Theses/Capstones/Creative Projects

This paper provides a survey of various research articles on context-aware asynchronous pronunciation training applications. First, a set of seven articles is reviewed and summarized. Next, they are synthesized over the three main topics of 1) automated speech recognition, 2) non-native speaker considerations in language learning, and 3) future directions for research and development within computer-assisted pronunciation training (CAPT). Research in the areas of acoustic and pronunciation modeling (both implicit and explicit), pedagogical considerations for CAPT application design, Goodness of Pronunciation algorithm scoring, accent recognition and neutralization, and more are discussed.

Monero: Powering Anonymous Digital Currency Transactions, Jake Braddy

Theses/Capstones/Creative Projects

Cryptocurrencies rely on a distributed public ledger (record of transactions) in order to perform their intended functions. However, the public’s ability to audit the network is both its greatest strength and greatest weakness: Anyone can see what address sent currency, and to whom the currency was sent. If cryptocurrency is ever going to take some of the responsibility of fiat currency, then there needs to be a certain level of confidentiality. Thus far, Monero has come out on top as the preferred currency for embodying the ideas of privacy and confidentiality. Through numerous cryptographic procedures, Monero is able to obfuscate …

Use Of Non-Linguistic Representation In A 1st Grade Classroom, Haylee Umble

Theses/Capstones/Creative Projects

Reading skills are difficult to comprehend for student who are English Language Learners, especially in first grade! Like many other majors, education majors have an "internship" called clinical practice or student teaching. This is the most influential time to put our learned skills to the test in the most genuine environment possible: a classroom for entire semester. For my clinical practice, I was placed in a on the English side of a dual-language 1^st grade classroom at an elementary school in the OPS School District. I discovered an area where there was struggle for many students. Therefore, I created …

Teaching Fraction Concepts To Third Grade Students With The Support Of Instructional And Assessment Strategies, Kaitlyn Brandl

Theses/Capstones/Creative Projects

This capstone project reports and analyzes the effects of utilizing differentiated instructional and assessment strategies in a third-grade classroom. The capstone will discuss the benefits and results of implementing two instructional strategies and two assessment methods during the instruction of a math unit in fraction concepts. The math unit was delivered over a period of 10 instructional days and included pre-assessment and post-assessments. Based on the data collected, student understanding and performance increased after integrating supports through differentiated instructional strategies. In this capstone, I will discuss the methods utilized to deliver instruction and assess student learning. Conclusions of the capstone …

Artificial Intelligence Applications For Optimizing Population And Clinical Drug Decision-Making Processes, Khulud Bukhari

Pharmaceutical Sciences (PhD) Dissertations

Introduction: In our study, we evaluated the application of ChatGPT4, an artificial intelligence chatbot, in the pharmacy field, specifically the capability of ChatGPT4 to extract and analyze FDA drug information, conduct a cost-effectiveness analysis of two antibiotics, and identify and classify adverse drugs events (ADE). We compare the results of ChatGPT4 with those from manual searches and specialized software programs. Methods: The first study used ChatGPT4 to extract and assess the quality of regulatory information for antibiotics indicated for complicated urinary tract infections (cUTI) approved by the FDA in 2014-2023. The second study involved comparing the cost-effectiveness analysis of cefiderocol …

Ucf Pegasus Plan – 3rd Grade – The Constitution, Shakira D. Reeves, Giulietta Wetzel, Elizabeth Pauly, Julia Cusack

Pegasus Plans: Social Studies Unit Plans for Florida Teachers

During this unit, students will explore how the U.S. Constitution serves as the foundation for government, fulfilling its purpose and addressing societal needs. Students will delve into the structures, functions, powers, and limitations of government as outlined in both the U.S. and Florida Constitutions. Additionally, students will also learn about Federalism, the multi-level nature of government, and will learn to recognize the different responsibilities of government at the local, state, and national levels. Lastly, students will practice identifying an author's purpose within informational texts as they deepen their understanding of complex concepts related to governance and constitutional frameworks.