Digital Commons Network^™

Black Radio’S Contribution To Collective And Cultural Memory: Personnel Perspectives Of Black Radio History In The United States, Kim Fox

Faculty Journal Articles

This interdisciplinary research investigates the significance of the community connection between Black radio personnel and their audiences through the lens of collective and cultural memory narratives. The study addresses two key research questions. First, how do Black radio personnel’s collective and cultural memories contribute to the Black public sphere? Second, what are the defining characteristics in developing parasocial relationships and interactions between Black radio personalities and their audiences? The qualitative research employs an autoethnographic methodology and a questionnaire, utilizing insights gained from the author’s experiences working at a Black-owned radio network and station. The questionnaire, distributed to key informants in …

A Probabilistic Approach To Estimate The Temporal Order Of Pathway Mutations Accounting For Intra-Tumor Heterogeneity, Menghan Wang, Yanqi Xie, Jinpeng Liu, Austin Li, Li Chen, Arnold Stromberg, Susanne Arnold, Chunming Liu, Chi Wang

Markey Cancer Center Faculty Publications

The development of cancer involves the accumulation of somatic mutations in several essential biological pathways. Delineating the temporal order of pathway mutations during tumori- genesis is crucial for comprehending the biological mechanisms underlying cancer development and identifying potential targets for therapeutic intervention. Several computational and statistical methods have been introduced for estimating the order of somatic mutations based on mutation profile data from a cohort of patients. However, one major issue of current methods is that they do not take into account intra-tumor heterogeneity (ITH), which limits their ability to accurately discern the order of pathway mutations. To address this …

Validating An Automated Rodent Ultrasonic Vocalization Data Collator, Devin Mark Kellis

Theses and Dissertations

Rodent ultrasonic vocalizations (USVs) are a key dependent measure within behavioral science that have translational relevance with respect to medical, especially neuropsychiatric, illnesses. In recent years, several programs have been developed to enable the recording, labeling, and parameterization of rodent USVs via conventional, machine learning, or deep learning approaches. However, there remains a need to further automate the downstream process of data collation so that labeled and classified USV parameters can be rapidly formatted and analyzed via statistical approaches based on experimenter preferences. The aim of this thesis was therefore to validate an automated vocalization data collator (AVDC) to expedite …

Master Of Social Work Portfolio, Courtney Marie Aadland-Lewis

Graduate Student Portfolios, Professional Papers, and Capstone Projects

No abstract provided.

Wide-Field Optical Coherence Tomography Imaging Improves Rate Of Change Detection In Progressing Glaucomatous Eyes Compared With Standard-Field Imaging, Christopher Bowd, Akram Belghith, Jasmin Rezapour, Jost B. Jonas, Leslie Hyman, Robert N. Weinreb, Linda M. Zangwill

Wills Eye Hospital Papers

PURPOSE: To compare rates of retinal nerve fiber layer change over time in healthy, eyes with nonprogressing glaucoma and eyes with progressing glaucoma using single wide-field (SWF) and optic nerve head (ONH) cube scan optical coherence tomography (OCT) images.

METHODS: Forty-five eyes of 25 healthy individuals and 263 eyes of 161 glaucoma patients from the Diagnostic Innovations in Glaucoma Study were included. All eyes underwent 24-2 visual field testing and OCT (Spectralis SD-OCT) ONH and macular imaging. SWF images (up to 43° × 28°) were created by stitching together ONH cube scans centered on the optic disc and macular cube …

A Cross-Sectional Analysis Of Preterm Birth Incidence And Survival In Al Kharj, Saudi Arabia, Mshari Alghadier, Muneera Alasraj, Ragab Elnaggar, Mashael Alazmi, Asma Aldawsari, Saud Alnadah, Faisal Alqahtani, Donia Zaghamir

Saudi Medical Journal

Objectives: To understand the prevalence and survival rates of preterm birth (PTB) is of utmost importance in informing healthcare planning, improving neonatal care, enhancing maternal and infant health, monitoring long-term outcomes, and guiding policy and advocacy efforts. Methods: The medical records of preterm infants admitted to the Neonatal Intensive Care Unit (NICU) with a diagnosis of prematurity at the Maternity and Children’s Hospital (MCH), Al Kharj, Saudi Arabia, were reviewed between January 2018 and December 2022. Data were collected on birth weight (BW), gender, number of live births, gestational age, mortality, nationality, APGAR score, length of stay in the NICU, …

Efficacy Of Home Healthcare On The Management Of Tracheostomy Patients, Nura A. Almansour, Yasmeen A. Alhedyan, Nada N. Alshathri, Razan S. Alsubaie, Sara Y. Alsuliman, Aamir A. Omair, Abdullah K. Alanazi, Amjad S. Alserayaa

Saudi Medical Journal

Objectives: To evaluated the home healthcare efficacy in managing tracheostomy patients at King Abdulaziz Medical City under the Ministry of National Guard Health Affairs. Home healthcare is care provided to patients in the convenience of their homes to ensure high-quality care based on healthcare providers’ supervision. Methods: This retrospective cohort study utilizing a non-probability consecutive sampling technique, including all available tracheal patients with no exclusion criteria, was carried out in Riyadh, Saudi Arabia, between January 2019 and June 2022. The collected data included patient demographic variables and respiratory settings (ventilation type, daily ventilation need, tracheostomy duration, and ventilator settings). The …

Creating And Delivering Audio Descriptions For Videos, Rosiana Natalie

Dissertations and Theses Collection (Open Access)

Despite anti-discrimination regulations mandating the provision of audio descriptions (ADs), the majority of online video content remains inaccessible to blind and low-vision (BLV) individuals. This is because these ADs are either absent or fail to adequately address the diverse and unique needs of the audience. Traditionally, content creators have relied on professionals to author ADs. However, this gold standard may not be accessible for some content creators because this method is still costly and has a long turnaround time. Moreover, when ADs are available, they tend to be static and unalterable, failing to cater to the unique preferences of BLV …

Examining A Regulatory Flexibility Framework Of Psychological Distress: Integrating Distress Tolerance, Emotion Differentiation, And Emotion Regulation Flexibility, Germaine Yue Qi Tng

Dissertations and Theses Collection (Open Access)

Several theoretical accounts identify emotion regulation (ER) difficulties, including poor abilities to withstand or distinguish negative emotions, as a transdiagnostic risk factor for symptoms of psychological distress. Considering this, nascent evidence hints that ER flexibility may be a mediating mechanism that explains the relationship between specific ER abilities (i.e., distress tolerance, negative emotion differentiation) and distress symptoms. Across time-lagged (Study 1) and three-wave longitudinal (Study 2) investigations of college-aged adults, a regulatory flexibility framework of distress was examined in which ER flexibility mediates the respective pathways from distress tolerance and negative emotion differentiation to psychological distress symptoms. Furthermore, we explored …

Decentralized Consensus And Governance For Collaborative Intelligence, Huiwen Liu

Dissertations and Theses Collection (Open Access)

The data economy today is becoming increasingly collaborative in nature. Take business intelligence, for example. To unleash the full potential of big data, it is essential to integrate multi-source data depicting entities from a multi-faceted and multi-modal perspective, which, not surprisingly, is not achievable by any company alone. In collaborative intelligence, there are two core issues, namely "trust" and "incentive". The core mechanisms to solve these two problems are consensus and tokenization separately.

To solve the trust problem more effectively, we propose a systematic consensus evaluation framework to investigate whether existing consensus algorithms can do so. After a lot of …

Toward A Biometric Privacy Act To Protect Individual Rights: What The United States Can Learn From The European Union And China, Sophia Hilsman

Cardozo International & Comparative Law Review

The note examines the regulatory frameworks governing biometric AI technologies, particularly facial recognition, in the United States, China, and the European Union. It argues that the U.S. currently lacks comprehensive federal legislation to protect individuals' privacy and civil liberties in the face of advancing biometric technologies. The analysis advocates for a balanced regulatory approach that mitigates the risks of mass surveillance and erosion of privacy while allowing for beneficial uses of biometric AI. The author proposes that Congress should adopt federal legislation modeled after the EU's GDPR to establish a baseline for biometric data protection, ensuring consistency and stronger safeguards …

Race Against The Clock: A Comparative Analysis Of New York State's And Germany's Ambitious High-Voltage Transmission Sitting Laws And What New York Can Adopt From The German Model, Andrew Leahy

Cardozo International & Comparative Law Review

The note argues that New York should adopt elements of Germany's centralized regulatory model to streamline the approval and construction of high-voltage transmission lines, which are critical for meeting renewable energy goals. While both New York and Germany face similar challenges in expanding their grids, Germany's centralized approach, including federal oversight and coordinated planning, has proven more efficient. The note critiques New York's decentralized and uncoordinated process, suggesting that adopting Germany's methods could help New York meet its ambitious renewable energy targets and reduce reliance on peaker plants.

2. Faculty, Saint Mary's College Of California

Faculty Handbook

No abstract provided.

Exchange Rates And Fundamentals In Developed And Emerging Markets, Rocky K. Laurel

DLSU Business & Economics Review

This paper investigates the relationship between exchange rates on the one hand and money supply and real output on the other, then compares the relationship in developed and emerging markets. It tests the validity of the flexible price monetary model using in-sample analysis to determine if there are long-term relationships among the variables and out-of-sample analysis to compare the predictive performance of the model against a random walk. It finds evidence for a relationship as predicted by the model, contrary to long-standing findings of no relationship. It also finds some evidence that foreign exchange rates of emerging markets are more …

The Yields That Bind: Treasury Bill Yields And The Philippine Corporate Bond Yield Spreads (Pre-Covid 2012–2019), Maurice Arce, Carlos Dorado, Justine Pascua, Paul Robles, Junette Perez

DLSU Business & Economics Review

The paper’s base reference is Duffee (1998). He examined the inverse relationship between the U.S. Treasury bill yields (TBY) and the corporate bond yield spreads (CBYS). Eight years of historical data on the Philippine CBYS from 2012–2019 and data on TBY were analyzed using OLS regression. To examine, if the results hold in the Philippines and given that the bond market in the country differs from the U.S. bond markets, will the results of Duffee (1998) persist? Although the paper focused on providing evidence on one of the most basic, well-established inverse relationships between TBY and inflation to CBYS, the …

2023 Kahramanmaras Earthquake Sequence: Geospatial Visualization And Analysis Of Multiple Building Damage Datasets, Alejandra Bravo, Jerry Hue Truong Luong, Anahid Behrouzi

Architectural Engineering

To learn from past earthquake events, a critical task is validating observations with data. After a significant seismic event like the 2023 Kahramanmaras Türkiye earthquake series, various organizations perform reconnaissance efforts to collect building response data. Some reconnaissance missions focus on visiting fewer buildings and recording detailed information (high-resolution, HR), while others aim to visit as many buildings as possible recording basic information (low-resolution, LR). Both dataset types are vital for learning, and the next step is analyzing and visualizing the data to validate in-field observations. This paper has three purposes: 1) examine a HR dataset by Degenkolb with 138 …

The Role Of Executive Function In Cognitive Reappraisal: A Meta-Analytic Review, Wei Xing Toh, Jun Sheng Keh, James J. Gross, Laura L. Carstensen

Research Collection School of Social Sciences

Cognitive reappraisal refers to the reinterpretation of a situation to alter its emotional meaning. Theoretically, executive functions (EFs), such as inhibition, updating, and shifting, are core elements of reappraisal processes. However, empirical studies have yielded inconsistent evidence as to whether and to what extent EFs are associated with reappraisal. To address this issue, we conducted a meta-analysis of the literature in which 179 effect sizes from 59 independent samples (N = 4,703) were included. Using random-effects metaregression with robust-variance estimates and small-sample corrections, we also examined whether variation in effect sizes could be accounted for by potential moderators, such as …

Time-Restricted Feeding Reveals A Role For Neural Respiratory Clocks In Optimizing Daily Ventilatory-Metabolic Coupling In Mice, Aaron A. Jones, Gabriella M. Marino, Deanna M. Arble

Biological Sciences Faculty Research and Publications

The master circadian clock, located in the suprachiasmatic nuclei (SCN), organizes the daily rhythm in minute ventilation (V̇e). However, the extent that the daily rhythm in V̇e is secondary to SCN-imposed O2 and CO2 cycles (i.e., metabolic rate) or driven by other clock mechanisms remains unknown. Here, we experimentally shifted metabolic rate using time-restricted feeding (without affecting light-induced synchronization of the SCN) to determine the influence of metabolic rate in orchestrating the daily V̇e rhythm. Mice eating predominantly at night exhibited robust daily rhythms in O2 consumption (V̇o2), CO2 production (V̇co2), and V̇e with similar peak times (approximately ZT18) that …

Perceptions Of Communities Of Practice And Sense Of Belonging: Focus Groups Of Academic Pediatric Faculty, Margaret P. Huntwork, Myo T. Myint, Emma Simon, Bonnie Desselle, Amy M. Creel

School of Medicine Faculty Publications

BACKGROUND: Providing the opportunity for collaboration around a central purpose to improve skills and exchange knowledge, the Community of Practice model can be useful for faculty development. A sense of belonging enhances the engagement in communities. Yet, the barriers and contributors to academic medicine faculty's sense of belonging in communities are not as well explored. METHODS: Through focus groups with 21 academic pediatric faculty conducted between January and March 2023, this qualitative study examined knowledge of Communities of Practice and the factors that affect sense of belonging and engagement. The authors iteratively coded transcripts to generate themes. RESULTS: Community accessibility; …

Assessing Rice Phenological Features With Hyperspectral Imaging Insights From Earth Surface Mineral Dust Source Investigation (Emit), Shahryar Fazli, Wenzhao Li, Surendra Maharjan, Hesham El-Askary

Mathematics, Physics, and Computer Science Faculty Articles and Research

In California's Central Valley, water management and crop health, particularly in rice cultivation, are critical. This paper details the application of Earth surface Mineral dust source InvesTigation (EMIT) hyperspectral imaging, specifically employing Spectral Correlation Mapper (SCM) and Spectral Information Divergence (SID), for precise phenological analysis. By aligning EMIT data with Hyperion satellite references, we address spectral and geographical discrepancies. Our methodology includes seasonal sampling of spectral curves to capture the phenological stages of rice. Results show a strong correlation (R ² = 0.86) between August EMIT and Reference dataset, emphasizing EMIT's utility in enhancing agricultural practices and water efficiency in …

Attribute-Based Fine-Grained Access Control Using Verifiable Credentials, Srinivasa Dumpa

Student Theses

In the era of digital transformation, ensuring secure and privacy-preserving access control mechanisms is of paramount importance. Traditional identity-based access control systems often fall short in providing granular control and user autonomy over digital identities. This thesis presents a novel approach to access control by leveraging the power of verifiable credentials and attribute-based access control. The proposed system introduces a decentralized and user-centric framework that enables fine-grained access control based on specific attributes encapsulated within verifiable credentials. These tamper-evident digital credentials, stored in a user's digital wallet, contain a rich set of attributes that can be selectively disclosed to grant …

Implementation, Evolution, And Laboratory Performance Of Methods-Based Proficiency Testing For Next-Generation Sequencing Detection Of Germline Sequence Variants, Karen D Tsuchiya, Birgit Funke, Madhuri Hegde, Avni Santani, Rhona J Souers, Szabolcs Szelinger, Jaimie Halley, Qin Zhao, Nicole Mot, Angshumoy Roy, Vanessa L Smith, Bing M Zhang, Karl Voelkerding, Ann M Moyer

Faculty, Staff and Students Publications

Context.—: Next-generation sequencing (NGS)-based assays are used for diagnosis of diverse inherited disorders. Limited data are available pertaining to interlaboratory analytical performance of these assays.

Objective.—: To report on the College of American Pathologists (CAP) NGS Germline Program, which is methods based, and explore the evolution in laboratory testing practices.

Design.—: Results from the NGS Germline Program from 2016-2020 were analyzed for interlaboratory analytical performance. Self-reported laboratory testing practices were also evaluated.

Results.—: From 2016-2020, a total of 297 laboratories participated in at least 1 program mailing. Of the 289 laboratories that provided information on tests offered, 138 (47.8%) offered …

Dna-Delivered Monoclonal Antibodies Targeting The P53 R175h Mutant Epitope Inhibit Tumor Development In Mice, Dafei Chai, Xu Wang, Praveen Neeli, Shan Zhou, Xingfang Yu, Kanaga Sabapathy, Yong Li

Faculty, Staff and Students Publications

The tumor suppressor p53 is the most common mutated gene in cancer, with the R175H as the most frequent p53 missense mutant. However, there are currently no approved targeted therapies or immunotherapies against mutant p53. Here, we characterized and investigated a monoclonal antibody (mAb) that recognizes the mutant p53-R175H for its affinity, specificity, and activity against tumor cells in vitro. We then delivered DNA plasmids expressing the anti-R175H mAb or a bispecific antibody (BsAb) into mice to evaluate their therapeutic effects. Our results showed that the anti-R175H mAb specifically bound to the p53-R175H antigen with a high affinity and …

Reducing Student Anxiety Using Neurofeedback-Assisted Mindfulness: A Quasi-Experimental Single-Case Design, David Christian, Cian L. Brown, Evan C. Smarinsky, Erin K. Popejoy, Allison Ames Boykin

Counseling, Leadership, and Research Methods Faculty Publications and Presentations

The authors implemented an A–B–A with follow-up quasi-experimental single-case research design to assess the effectiveness of a consumer-grade neurofeedback (NFB)-assisted mindfulness-based intervention (MBI) for reducing anxiety in high-achieving high school students (N = 5). Three of the participants from racial/ethnic minority and lower socioeconomic status (SES) backgrounds reported reduced anxiety as measured by the State-Trait Anxiety Inventory for Youth (STAI-Y) during the intervention. In contrast, the two participants who identified as White, higher SES did not report decreased anxiety during the intervention. Results provide initial support for the use of the NFB-assisted MBI used in this study as a …

A Klf2-Bmper-Smad1/5 Checkpoint Regulates High Fluid Shear Stress-Mediated Artery Remodeling, Hanqiang Deng, Jiasheng Zhang, Yewei Wang, Divyesh Joshi, Xinchun Pi, Sarah De Val, Martin A Schwartz

Faculty, Staff and Students Publications

Vascular remodeling to match arterial diameter to tissue requirements commonly fails in ischemic disease. Endothelial cells sense fluid shear stress (FSS) from blood flow to maintain FSS within a narrow range in healthy vessels. Thus, high FSS induces vessel outward remodeling, but mechanisms are poorly understood. We previously reported that Smad1/5 is maximally activated at physiological FSS. Smad1/5 limits Akt activation, suggesting that inhibiting Smad1/5 may facilitate outward remodeling. Here we report that high FSS suppresses Smad1/5 by elevating KLF2, which induces the bone morphogenetic protein (BMP) pathway inhibitor, BMP-binding endothelial regulator (BMPER), thereby de-inhibiting Akt. In mice, surgically induced …

Understanding The Genetic Complexity Of Puberty Timing Across The Allele Frequency Spectrum, Katherine A Kentistou, Lena R Kaisinger, Stasa Stankovic, Marc Vaudel, Edson Mendes De Oliveira, Andrea Messina, Robin G Walters, Xiaoxi Liu, Alexander S Busch, Hannes Helgason, Deborah J Thompson, Federico Santoni, Konstantin M Petricek, Yassine Zouaghi, Isabel Huang-Doran, Daniel F Gudbjartsson, Eirik Bratland, Kuang Lin, Eugene J Gardner, Yajie Zhao, Raina Y Jia, Chikashi Terao, Marjorie J Riggan, Manjeet K Bolla, Mojgan Yazdanpanah, Nahid Yazdanpanah, Jonathan P Bradfield, Linda Broer, Archie Campbell, Daniel I Chasman, Diana L Cousminer, Nora Franceschini, Lude H Franke, Giorgia Girotto, Chunyan He, Marjo-Riitta Järvelin, Peter K Joshi, Yoichiro Kamatani, Robert Karlsson, Jian'an Luan, Kathryn L Lunetta, Reedik Mägi, Massimo Mangino, Sarah E Medland, Christa Meisinger, Raymond Noordam, Teresa Nutile, Maria Pina Concas, Ozren Polašek, Eleonora Porcu, Susan M Ring, Cinzia Sala, Albert V Smith, Toshiko Tanaka, Peter J Van Der Most, Veronique Vitart, Carol A Wang, Gonneke Willemsen, Marek Zygmunt, Thomas U Ahearn, Irene L Andrulis, Hoda Anton-Culver, Antonis C Antoniou, Paul L Auer, Catriona L K Barnes, Matthias W Beckmann, Amy Berrington De Gonzalez, Natalia V Bogdanova, Stig E Bojesen, Hermann Brenner, Julie E Buring, Federico Canzian, Jenny Chang-Claude, Fergus J Couch, Angela Cox, Laura Crisponi, Kamila Czene, Mary B Daly, Ellen W Demerath, Joe Dennis, Peter Devilee, Immaculata De Vivo, Thilo Dörk, Alison M Dunning, Miriam Dwek, Johan G Eriksson, Peter A Fasching, Lindsay Fernandez-Rhodes, Liana Ferreli, Olivia Fletcher, Manuela Gago-Dominguez, Montserrat García-Closas, José A García-Sáenz, Anna González-Neira, Harald Grallert, Pascal Guénel, Christopher A Haiman, Per Hall, Ute Hamann, Hakon Hakonarson, Roger J Hart, Martha Hickey, Maartje J Hooning, Reiner Hoppe, John L Hopper, Jouke-Jan Hottenga, Frank B Hu, Hanna Huebner, David J Hunter, Helena Jernström, Esther M John, David Karasik, Elza K Khusnutdinova, Vessela N Kristensen, James V Lacey, Diether Lambrechts, Lenore J Launer, Penelope A Lind, Annika Lindblom, Patrik K E Magnusson, Arto Mannermaa, Mark I Mccarthy, Thomas Meitinger, Cristina Menni, Kyriaki Michailidou, Iona Y Millwood, Roger L Milne, Grant W Montgomery, Heli Nevanlinna, Ilja M Nolte, Dale R Nyholt, Nadia Obi, Katie M O'Brien, Kenneth Offit, Albertine J Oldehinkel, Sisse R Ostrowski, Aarno Palotie, Ole B Pedersen, Annette Peters, Giulia Pianigiani, Dijana Plaseska-Karanfilska, Anneli Pouta, Alfred Pozarickij, Paolo Radice, Gad Rennert, Frits R Rosendaal, Daniela Ruggiero, Emmanouil Saloustros, Dale P Sandler, Sabine Schipf, Carsten O Schmidt, Marjanka K Schmidt, Kerrin Small, Beatrice Spedicati, Meir Stampfer, Jennifer Stone, Rulla M Tamimi, Lauren R Teras, Emmi Tikkanen, Constance Turman, Celine M Vachon, Qin Wang, Robert Winqvist, Alicja Wolk, Babette S Zemel, Wei Zheng, Ko W Van Dijk, Behrooz Z Alizadeh, Stefania Bandinelli, Eric Boerwinkle, Dorret I Boomsma, Marina Ciullo, Georgia Chenevix-Trench, Francesco Cucca, Tõnu Esko, Christian Gieger, Struan F A Grant, Vilmundur Gudnason, Caroline Hayward, Ivana Kolčić, Peter Kraft, Deborah A Lawlor, Nicholas G Martin, Ellen A Nøhr, Nancy L Pedersen, Craig E Pennell, Paul M Ridker, Antonietta Robino, Harold Snieder, Ulla Sovio, Tim D Spector, Doris Stöckl, Cathie Sudlow, Nic J Timpson, Daniela Toniolo, André Uitterlinden, Sheila Ulivi, Henry Völzke, Nicholas J Wareham, Elisabeth Widen, James F Wilson, Lifelines Cohort Study, Danish Blood Donor Study, Ovarian Cancer Association Consortium, Breast Cancer Association Consortium, Biobank Japan Project, China Kadoorie Biobank Collaborative Group, Paul D P Pharoah, Liming Li, Douglas F Easton, Pål R Njølstad, Patrick Sulem, Joanne M Murabito, Anna Murray, Despoina Manousaki, Anders Juul, Christian Erikstrup, Kari Stefansson, Momoko Horikoshi, Zhengming Chen, I Sadaf Farooqi, Nelly Pitteloud, Stefan Johansson, Felix R Day, John R B Perry, Ken K Ong

Faculty, Staff and Student Publications

Pubertal timing varies considerably and is associated with later health outcomes. We performed multi-ancestry genetic analyses on ~800,000 women, identifying 1,080 signals for age at menarche. Collectively, these explained 11% of trait variance in an independent sample. Women at the top and bottom 1% of polygenic risk exhibited ~11 and ~14-fold higher risks of delayed and precocious puberty, respectively. We identified several genes harboring rare loss-of-function variants in ~200,000 women, including variants in ZNF483, which abolished the impact of polygenic risk. Variant-to-gene mapping approaches and mouse gonadotropin-releasing hormone neuron RNA sequencing implicated 665 genes, including an uncharacterized G-protein-coupled receptor, GPR83, …

High Throughput Plasma Proteomics And Risk Of Heart Failure And Frailty In Late Life, Diego Ramonfaur, Leo F Buckley, Victoria Arthur, Yimin Yang, Brian L Claggett, Chiadi E Ndumele, Keenan A Walker, Thomas Austin, Michelle C Odden, James S Floyd, Sandra Sanders-Van Wijk, Joyce Njoroge, Jorge R Kizer, Dalane Kitzman, Suma H Konety, Jennifer Schrack, Fangyu Liu, B Gwen Windham, Priya Palta, Josef Coresh, Bing Yu, Amil M Shah

Faculty, Staff and Student Publications

Importance: Heart failure (HF) and frailty frequently coexist and may share a common pathobiology, although the underlying mechanisms remain unclear. Understanding these mechanisms may provide guidance for preventing and treating both conditions.

Objective: To identify shared pathways between incident HF and frailty in late life using large-scale proteomics.

Design, setting, and participants: In this cohort study, 4877 aptamers (Somascan v4) were measured among participants in the community-based longitudinal Atherosclerosis Risk In Communities (ARIC) cohort study at visit 3 (V3; 1993-1995; n = 10 638) and at visit 5 (V5; 2011-2013; n = 3908). Analyses were externally replicated among 3189 participants …

4. Administrative Policies, Services And Facilities, Saint Mary's College Of California

Faculty Handbook

No abstract provided.

Transgender Women With Suppressed Testosterone Display Lower Burden Of Coronary Disease Than Matched Cisgender Men, Jordan E Lake, Han Feng, Ana N Hyatt, Hongyu Miao, Paula Debroy, Nicholas Funderburg, Kate Ailstock, Adrian Dobs, Sabina Haberlen, Jared W Magnani, Joseph B Margolick, Kate Mcgowan, Frank J Palella, Mallory D Witt, Shalender Bhasin, Matthew J Budoff, Wendy S Post, Todd T Brown

Faculty, Staff and Student Publications

Context: Cardiovascular disease (CVD) in transgender women (TW) may be affected by gender-affirming hormone therapy (GAHT) and HIV, but few data compare TW on contemporary GAHT to well-matched controls.

Objective: We compared CVD burden and biomarker profiles between TW and matched cisgender men (CM).

Methods: Adult TW on GAHT (n = 29) were recruited for a cross-sectional study (2018-2020). CM (n = 48) from the former Multicenter AIDS Cohort Study were matched 2:1 to TW on HIV serostatus, age ±5 years, race/ethnicity, BMI category and antiretroviral therapy (ART) type. Cardiac parameters were measured by CT and coronary atherosclerosis by coronary …

Project Evergreen: Ai Weed Detection In A Usfs Conifer Nursery, Kevin Wing, John Shovic

Idaho Conference on Undergraduate Research

This research, conducted under Project Evergreen, aims to develop a computer vision-based solution to detect weeds in conifer sapling rows within a United States Forest Service (USFS) nursery. The presence of weeds in these rows significantly impacts seedling viability, posing a challenge to reforestation efforts. Leveraging advanced machine vision techniques, this study aims to enhance the precision and efficiency of weed management practices by identifying weeds in the field, thereby improving seedling survival rates. The YOLO v8 model was selected for its superior real-time capabilities and high accuracy. YOLO (You Only Look Once) is a single-pass convolutional neural network known …