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Full-Text Articles in Entire DC Network
Gremlin Theory: A Film Art Of Joe Dante, Frank Falisi
Gremlin Theory: A Film Art Of Joe Dante, Frank Falisi
Dissertations, Theses, and Capstone Projects
This thesis seeks to establish the work of the filmmaker Joe Dante as a catalyzing and anarchic force let loose inside larger, dumber superstructures: linear narrativity, Hollywood, America, etc. It works to read the genre films he worked on—many of them made as popular entertainment for mainstream movie studios—as moments of actual subversion, allocating status quo (studio system) resources to create a biting-back against American imperial norms in the lingua franca of Marx and the Marx Brothers: gummy leisure-seeking stupidity and Gremlin transformation. This thesis seeks to argue that to understand Dante’s work is to understand pop transfiguration itself. This …
Mapping Nucleosome Stability: Linking Oncogenic Structural Alterations To Long-Range Allosteric Communication, Augustine C. Onyema
Mapping Nucleosome Stability: Linking Oncogenic Structural Alterations To Long-Range Allosteric Communication, Augustine C. Onyema
Dissertations, Theses, and Capstone Projects
The nucleosome core particle (NCP) is essential for chromatin structure and function, serving as the fundamental unit of eukaryotic chromatin. Oncogenic mutations in core histones disrupt chromatin dynamics, altering DNA repair and transcription processes. How DNA communicates with histones, and how this information propagates through the histone, has been suggested to be a cooperative process. Here, I investigate the molecular consequences of two mutations, H2BE76K and H4R92T, using 36 µs of all-atom molecular dynamics simulations on Anton2. I also characterize the kinetic correlation within histone/DNA domains via conditional activity (CONDACT) using the dihedral angle as our degrees of …
Kanak-Ish Misfits: Queer Imaginaries, Racialized Borders, And The Politics Of Care In Berlin, Germany, Faruk Seref
Kanak-Ish Misfits: Queer Imaginaries, Racialized Borders, And The Politics Of Care In Berlin, Germany, Faruk Seref
Dissertations, Theses, and Capstone Projects
This dissertation examines queer Muslim experiences of border politics, racialization, and care in Berlin, Germany. By formulating bordering as a domineering and oppressive practice of boundary-making, I study how global bordering mechanisms shape and disrupt structures of care, caring, and being cared for. With an intersectional focus on race, gender, sexuality, and sex, I argue that borders are simultaneously materialized and challenged in varying localities, including the nightclub, the queer scene, the diasporic neighborhoods, and households. Ultimately, viewing collective care as fundamental to survival, healing, resistance, and building non-punitive lifeworlds, I theorize the counter-hegemonic practices of queers of color through …
The Evolution Of U.S. Geoeconomic Grand Strategy Toward China And South Korea’S Strategic Space: A Comparative Analysis Of Neomercantilist Types In The Trump And Biden Administrations, Hyungbo Kim
Dissertations, Theses, and Capstone Projects
This study examines the evolutionary trajectory of U.S. geoeconomic grand strategy toward China from the inauguration of the first Trump administration in 2017, through the Biden administration, to the second Trump administration launched in 2025, while exploring South Korea’s survival strategies in response. The findings confirm that U.S. foreign economic policy has radicalized into "Expanded Malevolent Neomercantilism," which moves beyond simple protectionism to weaponize global economic networks in the name of national security and exploit even allies.
According to the analysis, the U.S. progressed from the "Malevolent Neomercantilism" of Trump's first term, which focused on trade deficits, to the "Developmental …
A Data Analysis Study Of Temperature Based On California Cooperative Oceanic Fisheries Investigations (Calcofi) Data., Afsana Mimi
A Data Analysis Study Of Temperature Based On California Cooperative Oceanic Fisheries Investigations (Calcofi) Data., Afsana Mimi
Dissertations, Theses, and Capstone Projects
This research presents an integrated analytical framework for predicting ocean temperatures using long-term observations from the California Cooperative Oceanic Fisheries Investigations (CalCOFI) data files. The study applies advanced data engineering and statistical modeling to assess how a variety of indicators, such as salinity, dissolved oxygen, key nutrients, and ocean depth shape oceanic temperature patterns along the California coastline. Using Microsoft SQL Server software for large-scale data integration and the R for statistical packages (R Core Team, 2025) for statistical computation, I developed and compared multiple regression models, including the ridge regression model, to evaluate the relative influence of physical and …
Considering Numerical Relativity For Upgrades In Mcfacts Merger Dynamics, Shawn K. Ray
Considering Numerical Relativity For Upgrades In Mcfacts Merger Dynamics, Shawn K. Ray
Dissertations, Theses, and Capstone Projects
Binary black hole mergers (BBH), some likely originating from active galactic nuclei (AGN), are observed by ground-based detectors such as LIGO-Virgo-KAGRA (LVK) and will be detected by future space-based detectors such as the Laser Interferometer Space Antenna (LISA) and the Laser Interferometer Lunar Antenna (LILA). The dynamics of AGN may be responsible for a significant fraction of BBH mergers soon to be observed by LISA and LILA, yet the dynamics of BBH mergers within AGN disks remains ambiguous despite their appearance in gravitational wave observations. Monte carlo For AGN Channel Testing and Simulation (McFACTS) is an open-source software used to …
Immunomodulatory And Signaling Molecules From Plant-Associated Bacteria: Toll-Like Receptor 4 Agonist Adjuvants And Diketopiperazine-Mediated Communication, Marian Romaine
Dissertations, Theses, and Capstone Projects
Medicinal plants and their associated microbiomes constitute a rich source of bioactive natural products with applications in immunotherapy and microbial ecology. Herbal formulations have long been valued for safe immune enhancement, while bacterial signaling molecules govern community behaviors critical to pathogenesis, symbiosis, and environmental processes. Bacterial lipopolysaccharides (LPS) from plant-associated Gram-negative bacteria have emerged as potent TLR4 agonists, yet their endotoxic potential limits direct use, and diketopiperazines (DKPs) serve as versatile quorum-sensing mediators capable of modulating biofilms in mixed microbial systems.
The work in this thesis comprises two independent but complementary research strands. The first strand pursued the engineering of …
Inductive Biases In Field-Level Cosmological Inference From Galaxy Catalogs, James O'Connor Baldwin
Inductive Biases In Field-Level Cosmological Inference From Galaxy Catalogs, James O'Connor Baldwin
Dissertations, Theses, and Capstone Projects
We perform field-level likelihood-free inference of the matter density parameter Ωm from simulated galaxy catalogs using machine learning models with differing inductive biases. Using features extracted from hydrodynamic simulations in the CAMELS suite, we investigate how both observable choice and model architecture govern the extraction of cosmological information. We consider galaxy positions and line-of-sight peculiar velocities, both separately and in combination, and compare permutation-invariant Deep Sets, implemented with either standard multilayer perceptrons (MLPs) or Kolmogorov–Arnold Networks (KANs), to graph neural networks (GNNs) implemented with MLPs, which explicitly encode spatial relations. We evaluate inference performance under both in-distribution and out-of-distribution (OOD) …
Three Degrees Of Representation: How Genai Filters, Retrieves, And Remixes Lesbian Film Data, Maria G. Baker
Three Degrees Of Representation: How Genai Filters, Retrieves, And Remixes Lesbian Film Data, Maria G. Baker
Dissertations, Theses, and Capstone Projects
This project investigates how generative AI systems assemble, filter, and represent Lesbian film data. Through auditing GenAI outputs across multiple dimensions (text, images, metadata), 3°R explores what gets included, excluded, and transformed in the process.
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Three Degrees of Representation is a public website (https://mgb513.github.io/lesfilm-meets-AI/) featuring an investigation of AI-generated images and texts in response to Lesbian film data. Filtering simple prompts based on Lesbian film titles through the algorithms of AI image and text generators makes visible how these systems digest and remix existing (training) data, and how aspects of Lesbian representation are either amplified or suppressed …
Beyond The Veil Of Modernity: René Guénon, Prophet Of The Metapolitical Imaginary, Frederic Colier
Beyond The Veil Of Modernity: René Guénon, Prophet Of The Metapolitical Imaginary, Frederic Colier
Dissertations, Theses, and Capstone Projects
Heralded by some as one of the greatest intellectuals of the 20th century, French metaphysician René Guénon (1886-1951) is also the controversial father of Primordial Tradition, a metaphysics designed to remedy the decline of Western civilization. Guénon viewed the West in the grip of a prolonged cycle of degeneration. He sought to implement a pseudo-authoritarian spiritual reset that required a total rejection of its Western intellectual heritage and an embrace of Eastern doctrines.
Focusing on his landmark book The Crisis of the Modern World (1927), the dissertation examines how Guénon implemented his controversial reset. After outlining the religious, cultural, and …
Identifying Textual Predictors Of Early Termination In Clinical Trials In Medicine: An Explainable Machine-Learning Study, Rohan Ramnarain
Identifying Textual Predictors Of Early Termination In Clinical Trials In Medicine: An Explainable Machine-Learning Study, Rohan Ramnarain
Dissertations, Theses, and Capstone Projects
About one in five clinical trials in medicine ends early, wasting valuable resources and reducing the evidence available for developing life-saving medical treatments. This project uses a method called Trial2Vec, which is a self-supervised machine-learning method that converts clinical trial documents into dense numerical representations that capture their key design and clinical characteristics, to turn each proposed clinical trial’s written protocol into a compact numerical profile (a process referred to as embedding). These profiles are then paired with a predictive machine learning models to identify the words and phrases in the trial documents that can signal a higher risk of …
A Machine Learning Approach To Disentangling Developmental Language Disorder From Typical Development In Russian-Speaking Children, Katsiaryna Aharodnik
A Machine Learning Approach To Disentangling Developmental Language Disorder From Typical Development In Russian-Speaking Children, Katsiaryna Aharodnik
Dissertations, Theses, and Capstone Projects
This study investigated a machine learning (ML) approach to identifying Developmental Language Disorder (DLD) in Russian-speaking children using narrative data. ML methods can capture subtle linguistic patterns that distinguish typical and atypical development, which is especially important in cross-linguistic contexts where morphosyntactic variation affects the manifestation of DLD. Diagnosis remains challenging in less-studied languages due to limited knowledge of language-specific deficits and a lack of validated assessment tools. This study evaluated whether ML algorithms can provide a more efficient alternative to traditional screening methods.
Two binary classification studies were conducted using corpus data: 1) classification of narratives told by Russian …
School Just Wasn't For Me: Investigating The Intersections Of Education, Incarceration, And Improvisation, Kelly L. Brady
School Just Wasn't For Me: Investigating The Intersections Of Education, Incarceration, And Improvisation, Kelly L. Brady
Dissertations, Theses, and Capstone Projects
New York City is the largest city in the United States and home to the nation's largest school system. NYC public schools are also the country's most segregated, according to a 2021 report from the UCLA Civil Rights Project. This qualitative, Arts-Based Research study follows the development and performance of an applied theater piece created by formerly incarcerated and court-involved youth exploring their early educational experiences before encountering the juvenile justice system. Using Disability/Critical Race Theory (DisCrit) and Critical Performance Ethnography this project investigates how structural systems of education and incarceration intersect to construct youth as "others," including special education, …
Muon Lifetime: Theory, Experiment, And Simulation, Soren Agustin Munoz
Muon Lifetime: Theory, Experiment, And Simulation, Soren Agustin Munoz
Physics
This senior project investigates the muon lifetime through three complementary approaches: theoretical calculation, laboratory measurement, and computational simulation. The theoretical component develops the necessary background from relativistic field theory to the effective weak interaction, culminating in the leading-order Fermi-theory prediction of τ ≈ 2.2 μs, which explains why the muon lifetime lies on the microsecond scale.
The experimental component measures the lifetime of stopped cosmic-ray muons using a plastic scintillator, photomultiplier tube, and analog timing electronics. A binned Poisson likelihood fit to the primary 15-day acquisition run τ = 2.17+0.03-0.09 μs, consistent with the accepted value within the …
From Gaming To Politics: The Impact Of Political Chatter By Social Media Influencers On Consumer Engagement With Non-Political Content, Mahdi Niknejad Moghadam
From Gaming To Politics: The Impact Of Political Chatter By Social Media Influencers On Consumer Engagement With Non-Political Content, Mahdi Niknejad Moghadam
Marketing Faculty Publications and Presentations
Social media influencers (SMIs) have become integral to digital marketing, shaping consumer perceptions and promoting products and services. While some SMIs are dedicated to political content or develop such content occasionally, nonpolitical SMIs may also engage in political chatter within their usual content. This study examines the effects of such chatter on consumer engagement by focusing on gaming SMIs. The main analysis is based on a dataset of 43,892 videos from 200 SMIs. The findings indicate that, overall, political chatter intensity in non-political content negatively impacts user engagement. However, this adverse effect is mitigated when SMIs express negative emotions, i.e., …
Quasi-Judicial Immunity Misapplied, Claire Hodges
Quasi-Judicial Immunity Misapplied, Claire Hodges
University of Chicago Law Review
Multiple circuit courts have extended quasi-judicial immunity—a form of judicially derived, absolute immunity—to sheriffs, marshals, and bailiffs when they execute judicial orders. In some circuits, that immunity extension covers the use of excessive force by the officer, even if that force is outside the scope of the order they are executing.
This Comment argues that the trend of lower courts extending quasi-judicial immunity to enforcement officers is inconsistent with the Supreme Court’s absolute immunity doctrine. A survey of the opinions in which the Court has granted absolute immunity to a government official reveals four considerations guiding the Court’s decision. The …
Aggregation And The “Universal” Injunction, Portia Pedro, Adam N. Steinman
Aggregation And The “Universal” Injunction, Portia Pedro, Adam N. Steinman
Faculty Scholarship
In this Essay, we begin with a brief summary of the CASA decision’s holding regarding the availability of “universal” injunctions. Part II discusses the relationship between remedies and judicial review and the important role that such injunctions play in that regard. Part III explores how class actions could serve as an alternative path for federal courts, after engaging in judicial review, to make their decisions meaningful by requiring officials to comply with the law and to cease illegal actions or policies. We also respond to several objections to the use of class actions in this context. The final Part addresses …
The Supreme Court Under Threat: Early Lessons In Judicial Self-Protection, Curtis A. Bradley, Neil S. Siegel
The Supreme Court Under Threat: Early Lessons In Judicial Self-Protection, Curtis A. Bradley, Neil S. Siegel
Faculty Scholarship
This Essay explores how the U.S. Supreme Court, despite being vulnerable to defiance of its decisions and political retaliation, has developed tools of judicial self-protection to preserve its institutional authority and thus its capacity to sustain the Constitution and the rule of law. Arguing that the Court performs not only a legal role that requires interpretation of the law but also a political one that demands institutional preservation, the Essay examines how the Court has historically navigated political threats by using a range of tools—including avoidance, delay, narrow rulings, strategic dicta, and rhetorical appeals. The Essay focuses on three nineteenth-century …
Making The Party Presentation Principle Safe For Originalism, Randy E. Barnett, Lawrence B. Solum
Making The Party Presentation Principle Safe For Originalism, Randy E. Barnett, Lawrence B. Solum
Faculty Scholarship
The Supreme Court sometimes adheres to what it calls the “party presentation principle”—terminology that dates back to 2008. Although judicial articulations of the principle have been inconsistent and imprecise, the gist is the familiar notion that courts should resolve cases on the basis of the issues and reasons presented by the parties to the dispute. Conversely, questions not properly raised by the parties should be avoided by the Court. Thus, the Court has on several occasions declined to address arguments outside the scope of the questions raised by the parties in their petition for certiorari.
For originalists, the importance of …
Evolving Networks: Information Exchanges Reshaping Of Global Finance, Andrew P. Morriss, Charlotte Ku
Evolving Networks: Information Exchanges Reshaping Of Global Finance, Andrew P. Morriss, Charlotte Ku
Faculty Scholarship
This article challenges the characterization of international financial centers (IFCs), often called "tax havens," as enablers of tax evasion and money laundering. Drawing on an extensive analysis of tax treaties, regulatory statutes, and historical literature, we explore the evolution of the global information exchange network, its impact on integrating IFCs into the global financial system, and the resulting curtailment of their use for illicit purposes. The expansion of treaties, from Mutual Legal Assistance Treaties (MLATs) to Tax Information Exchange Agreements (TIEAs) and multilateral frameworks like the OECD's Common Reporting Standard (CRS), has significantly limited the potential for secrecy-driven financial activities …
Jurisdictional Waters, Jamison E. Colburn
Ppg-Sport: A Dataset For Reliable Heart Rate Monitoring From Wrist Ppg Under Dynamic Sports Conditions, Changshuo Hu, Hung Manh Pham, Yiming Zhang, Guanru Yan, Xiao Ma, Yuezhong Wu, Thivya Kandappu, Archan Misra, Dong Ma
Ppg-Sport: A Dataset For Reliable Heart Rate Monitoring From Wrist Ppg Under Dynamic Sports Conditions, Changshuo Hu, Hung Manh Pham, Yiming Zhang, Guanru Yan, Xiao Ma, Yuezhong Wu, Thivya Kandappu, Archan Misra, Dong Ma
Research Collection School Of Computing and Information Systems
Photoplethysmography (PPG) has become a cornerstone of physiological sensing in wearable devices, enabling non-invasive monitoring of heart rate and related biomarkers. However, its reliability deteriorates sharply under dynamic, high-intensity, or non-periodic motions such as those in sports, where existing datasets fail to capture realistic wrist dynamics. To address this gap, we introduce PPG-Sport, the first large-scale dataset designed for heart rate monitoring from wrist-worn PPG under real sports conditions. The PPG-Sport dataset includes synchronized PPG, inertial measurement unit (IMU), and electrocardiography (ECG) recordings from both wrists of 30 participants across six representative activities: stationary, walking, running, badminton, table tennis, and …
Low-Cost Path-Loss Characterization For Underground Mine Tunnels Using Lora Transceivers At 915 Mhz, Hilary Kelechi Anabi, Samuel Frimpong, Muhammad Azeem Raza
Low-Cost Path-Loss Characterization For Underground Mine Tunnels Using Lora Transceivers At 915 Mhz, Hilary Kelechi Anabi, Samuel Frimpong, Muhammad Azeem Raza
Mining Engineering Faculty Research & Creative Works
Accurate path-loss models are essential for planning reliable wireless networks in underground mines, yet existing characterization studies rely on specialized channel sounders and vector network analyzers costing tens of thousands of dollars, placing them beyond the reach of most mine operators. This paper demonstrates that LoRa transceivers costing approximately US $15 per node can serve as a self-contained path-loss measurement instrument, logging the received signal strength indicator (RSSI) and signal-to-noise ratio (SNR) directly to a CSV file over a standard USB serial connection. A measurement campaign conducted at the Missouri S&T Experimental Mine on 31 March 2026 collected 4801 packets …
Phases And Dynamics Of An Impurity Immersed In One-Dimensional Quantum Droplets, Dimitrios Diplaris, Ilias A. Englezos, Friethjof Theel, Peter Schmelcher, Simeon I. Mistakidis
Phases And Dynamics Of An Impurity Immersed In One-Dimensional Quantum Droplets, Dimitrios Diplaris, Ilias A. Englezos, Friethjof Theel, Peter Schmelcher, Simeon I. Mistakidis
Physics Faculty Research & Creative Works
We explore the ground-state properties of a single impurity immersed in a one-dimensional quantum droplet medium formed by a two-component Bose mixture. Relying on ab initio simulations, we demonstrate that tuning the impurity–droplet interactions allows to controllably reshape the droplets' density profiles and associated correlation patterns. For attractive impurity-medium couplings, the impurity becomes localized within the droplet, which exhibits a density hump at the vicinity of the impurity, while repulsive interactions facilitate phase separation. Comparing our many-body results with the appropriate extended Gross–Pitaevskii description, we find adequate agreement for the droplet density profiles, with the effective field approach systematically overestimating …
Fluency ≠ Literacy: Practical Strategies To Scaffold, Not Offload, Rachel Rupprecht, Heidi Keller, Vanessa Hörmann
Fluency ≠ Literacy: Practical Strategies To Scaffold, Not Offload, Rachel Rupprecht, Heidi Keller, Vanessa Hörmann
Teaching & Learning with AI
This open-access resource kit helps faculty transition students from passive AI outsourcing to critical evaluation and essential skill cultivation. It includes 11 Assignment Templates & Rubrics, a Template Selector Gem, an AI Literacy Coach Gem, a Mindset Shifts & Expert Blind Spots visual guide, and student-facing resources.
High-Pressure Studies Of Magnetic Topological Materials, Greeshma Chireckal Jose
High-Pressure Studies Of Magnetic Topological Materials, Greeshma Chireckal Jose
ETDs from 2020-2029
Quantum technology leverages the principles of quantum mechanics to transform emerging fields such as quantum computing, spintronics, and next-generation electronics. A crucial step in advancing this frontier is the detailed understanding of fundamental quantum phenomena in materials that can drive quantum innovation. This research aims to systematically investigate quantum phase transitions and unconventional emergent behaviors in magnetic topological materials subjected to external pressure. This study focuses on three representative systems: EuCd2As2, EuMnBi2, and FeSn, each serving as a model for exploring intrinsic magnetic topological states. EuCd2As2, a candidate Weyl semimetal (WSM), is expected to exhibit pressure-induced topological phase transitions, making …
Inverse Modeling The Geo-Spread Of Covid-19 In Brazil, Cameron Keith Mills
Inverse Modeling The Geo-Spread Of Covid-19 In Brazil, Cameron Keith Mills
ETDs from 2020-2029
In 2021 Fitzgibbon, Morgan, Webb, and Wu used a modified SEIR (susceptible, exposed, infected, and recovered) model to predict how COVID-19 spread through Brazil [12]. For their model, six constant coefficients were used that were fitted, referenced, or assumed. In this thesis, we geo-spatially modify their SEIR model and formulate an inverse problem to recover the now spatial coefficients of the model. We first show there exists a unique solution to the modified model. To solve the inverse problem, we modify an inverse method [17] that focused on minimizing convex functionals. These recovered spatial coefficients can be used with Matlab’s …
The Aurora Survey, Ali Ahmad Khostovan, Ryan L. Sanders, Alice E. Shapley, Michael W. Topping, Naveen A. Reddy, Alex M. Garcia, Danielle A. Berg, Leonardo Clarke, Fergus Cullen, Richard S. Ellis, N. M.Förster Schreiber, Karl Glazebrook, Tucker Jones, Derek J. Mcleod, Anthony J. Pahl, Max Pettini, Paul Torrey
The Aurora Survey, Ali Ahmad Khostovan, Ryan L. Sanders, Alice E. Shapley, Michael W. Topping, Naveen A. Reddy, Alex M. Garcia, Danielle A. Berg, Leonardo Clarke, Fergus Cullen, Richard S. Ellis, N. M.Förster Schreiber, Karl Glazebrook, Tucker Jones, Derek J. Mcleod, Anthony J. Pahl, Max Pettini, Paul Torrey
Physics and Astronomy Faculty Publications
We present new constraints on the mass–metallicity (MZR) and fundamental metallicity relations (FMR) using a sample of 34 galaxies at 1.38 ≤ z ≤ 3.5 (median z = 2.28). These galaxies have direct Te measurements from [O iii]4363 Å and/or [O ii]7320,7331 Å auroral emission lines detected with JWST/NIRSpec as part of the AURORA survey. The detection of both oxygen auroral lines allows for dual-zone direct Te measurements and expands the dynamic range in (Formula presented) 12+log(O/H) (7.68–8.65 dex), stellar mass (108–1010.4 M⊙), and star formation rate (1–100 M⊙ yr−1) …
Holographic Description Of 4d Maxwell Theories And Their Code-Based Ensembles, Ahmed Barbar, Anatoly Dymarsky, Alfred Shapere
Holographic Description Of 4d Maxwell Theories And Their Code-Based Ensembles, Ahmed Barbar, Anatoly Dymarsky, Alfred Shapere
Physics and Astronomy Faculty Publications
We formulate a precise holographic duality between an ensemble of 4d U(1)g Maxwell theories living on a spin four-manifold M4 and a topological Abelian BF-type 2-form theory of level N, summed over all five-manifolds with boundary M4. The elements of the boundary ensemble are Abelian gauge theories specified by self-dual symplectic codes over ℤN, that parameterize topological boundary conditions in the 5d TQFT. Similarly, the equivalence classes of topologies distinguished by the 5d theory are parameterized by orthogonal self-dual codes. Hence the holographic duality can be reformulated in the language of quantum stabilizer codes. …
Dock7 Is A Novel Modifier Of Duchenne Muscular Dystrophy Pathology, Katherine English
Dock7 Is A Novel Modifier Of Duchenne Muscular Dystrophy Pathology, Katherine English
ETDs from 2020-2029
Duchenne muscular dystrophy (DMD) is a progressive, x-linked neuromuscular disorder affecting 1/5000 male births every year. DMD results from mutations in DMD, a critical structural protein within the muscle. In the absence of Dystrophin, the muscle degrades, increasing inflammation, destabilizing the cell membrane and going through constant cycles of regeneration which depletes the stem cell population. Over time, muscle tissue is replaced by fibrosis and adipose tissue, leading to loss of ambulation, respiratory and cardiac failure leading to death by early 20s. The standard of care for DMD patients is corticosteroid treatment. However, gene therapies have recently emerged which present …