Digital Commons Network^™

Ultra-Relativistic Electron Flux Enhancement Under Persistent High Speed Solar Wind Stream, L R. Alves, L A. Da Silva, V Deggeroni, J P. Marchezi, P R. Jauer, G B D Silva, D G. Sibeck

Faculty Publications

The physical mechanisms usually applied to explain the relativistic electron enhancement have been delved into to elucidate non-adiabatic electron acceleration resulting in the ultra-relativistic electron population observed in the outer radiation belt. We considered multisatellite observations of the solar wind parameters, magnetospheric waves, and particle flux to report an unusual local acceleration of ultra-relativistic electrons under a prolonged high-speed solar wind stream (HSS). A corotating interaction region reaches the Earth’s bowshock on August 3, 2016, causing a minor geomagnetic storm. Following this, the magnetosphere was driven for 72 h by a long-term HSS propagating at 600 km/s. During this period, …

Re: Comment Letter For Bpsou Draft Phase I Design Investigation Evaluation Report (Dated September 25, 2024), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

2024-11-15 Agenda Book, Morehead State University. Board Of Regents.

Morehead State Board of Regents Agenda Books and Meeting Minutes

Agenda book for the Board of Regents meeting of November 15, 2024, which include the Audit Committee meeting agenda and the Board meeting minutes for October 11, 2024.

A Proposal To Rebalance Direct Democracy In The Ohio Constitution, Mark Wagoner

Cleveland State Law Review

On October 27, 2023, Cleveland State Law Review hosted an in-person Symposium to convene academics, legal practitioners, community advocates, and judges for a robust and timely conversation about democracy’s promise and the fight for its future. This Symposium piece will reiterate some of the conversations by panelists discussing the use of law to become Guardians of Justice, the relationship between education and democracy, and the Ohio Constitution as a tool for recapturing the state’s democratic values.

Improper Indeterminate Incarceration: Navigating The Constitutional Quandaries Of The Reagan Tokes Law's Powers And Procedures, Sophie M. Piteo

Cleveland State Law Review

This Article advocates for an amendment to the statutory provisions that make up Ohio’s indefinite sentencing scheme to better protect offender’s constitutional rights. Through an analysis of the Reagan Tokes Law and the Ohio Supreme Court’s ruling in State v. Hacker, this Article traces the evolution of Ohio’s indefinite sentencing framework, which was reinstated in 2019. It contrasts the current scheme with the previously invalidated, but very similar, Bad Time Law, which was struck down in 2000 for violating the separation of powers clause and due process rights. While the Reagan Tokes Law emerged from concerns for public safety …

Direct Democracy: Ohio Style, Steven H. Steinglass, Ernest M. Oleksy

Cleveland State Law Review

This Article is an expansion of comments by Steven H. Steinglass at a Symposium on Democracy sponsored by the Cleveland State Law Review and held on October 27, 2023. The Symposium looked broadly at threats to democracy, but the panel on which he participated focused more narrowly on the Ohio Constitution and Democracy. The Article reviews the history of direct democracy in Ohio with an emphasis on the constitutional initiative. Part I of this Article discusses the historical origins of direct democracy in Ohio and the iconic Ohio Constitutional Convention of 1912 that proposed Ohio’s direct democracy amendment. Particular …

Robust Data-Driven Run-To-Run Control Via One-Step Constrained Optimization For Automated Serial Sectioning, Rhianna M. Oakley

Mechanical Engineering ETDs

This Thesis develops a one-step predictive run-to-run controller (R2R-MPC) for automating a mechanical serial sectioning (MSS) system. MSS is a destructive material analysis process that iteratively removes slices of material and captures 2D images, reconstructing them into 3D representations. Commonly used in material science for characterizing materials and failure analysis, MSS typically operates in an open-loop fashion, which experiences high variability in material removal due to system disturbances. To address this, a robust closed-loop R2R-MPC is presented, modeling MSS process uncertainty using a linear differential inclusion identified from operational historical data. The R2R-MPC is posed as an optimization problem that …

Something Is Rotten In The State Of Healthcare: Accountability, Affordability, And The Court Of Public Opinion, Isabelle Breier

Duke Law & Technology Review

Many countries worldwide recognize a right to health and provide legal recourse for securing that right. By contrast, for many Americans, there is no legal right or remedy that enables them to access healthcare if they cannot afford it. While there are some statutes and measures in place, such as the Emergency Medical Treatment and Active Labor Act (EMTALA) and Medicaid, coverage remains piecemeal and access to healthcare is not guaranteed. Conditioning people’s access to healthcare upon their ability to pay violates the foundational bioethical principle of justice. In the United States, individuals and advocates use social media to fill …

Understanding Teachers’ Perceptions Of Best Practices For English Language Learners, Joshua Daniel Davis

Walden Dissertations and Doctoral Studies

In a district where only 5% of ELLs were deemed language proficient, the problem was the need to understand teacher perceptions of best practices to increase English language learner (ELL) achievement in reading and writing. The purpose of this qualitative study was to examine teacher perceptions of best practices to support ELLs in improving their reading and writing in a heterogeneous high school classroom in a Mid-Atlantic school district. The framework that supported this study was the Cummins model on learners’ language use because it guides teaching and assessing students’ vocabulary acquisition in various contexts. The two research questions probed …

1245 Stratford, Llc V. Osboume

All Decisions

In this nonpayment eviction proceeding, the landlord sought to collect rent arrears for a rent-stabilized apartment. The tenant raised defenses, including illegal building alterations and lack of a valid Certificate of Occupancy. The court ruled that the landlord's failure to comply with the Multiple Dwelling Law (MDL) barred rent recovery, leading to the dismissal of the case in favor of the tenant.

Resolution Enhancement For High Numerical Aperture Extreme Ultraviolet Lithography Using Aperiodic Multilayer Masks, W Ethan Maguire

Theses

As extreme ultraviolet lithography tools with higher image numerical apertures are introduced, the range of angles at the mask multilayer are increased. This represents a challenge for maintaining through-angle mask reflection using the current periodic mask multilayer structures. In addition to reflectance amplitude, the phase of reflected light, which plays an important role in imaging, is also strongly influenced by increasing angles. The propagation of light through each bilayer in the stack imparts a phase shift based on incidence angle. This accumulates over many layers, inducing phase effects which are unique to each illumination point. While adjustments to multilayer period …

East Drive Housing Development Corporation V. Lawrence

All Decisions

The landlord sought discovery sanctions and vacatur of a note of issue due to the tenant's failure to comply with discovery orders. The tenant was found to have willfully obstructed the discovery process and his answer was struck. The court also granted the landlord's motion to vacate the note of issue, finding no cooperation from the tenant and delays in the discovery process.

Healing Online Abuse Through Community-Based Art: An Exploratory Investigation, Sarah Auletta

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

Understanding Teachers’ Perceptions Of Best Practices For English Language Learners, Joshua Daniel Davis

Walden Dissertations and Doctoral Studies

In a district where only 5% of ELLs were deemed language proficient, the problem was the need to understand teacher perceptions of best practices to increase English language learner (ELL) achievement in reading and writing. The purpose of this qualitative study was to examine teacher perceptions of best practices to support ELLs in improving their reading and writing in a heterogeneous high school classroom in a Mid-Atlantic school district. The framework that supported this study was the Cummins model on learners’ language use because it guides teaching and assessing students’ vocabulary acquisition in various contexts. The two research questions probed …

Epigenome Reprogramming Through H3k27 And H3k4 Trimethylation As A Resistance Mechanism To Dna Methylation Inhibition In Brafv600e-Mutated Colorectal Cancer, Hey Min Lee, Ajay Kumar Saw, Van K Morris, Stefania Napolitano, Christopher Bristow, Sanjana Srinivasan, Micheal Peoples, Alexey Sorokin, Preeti Kanikarla Marie, Jonathan Schulz, Anand K Singh, Christopher Terranova, Oluwadara Coker, Abhinav Jain, Scott Kopetz, Kunal Rai

Faculty, Staff and Student Publications

Purpose: BRAFV600E-mutated colorectal cancer exhibits a strong correlation with DNA hypermethylation, suggesting that this subgroup of tumors presents unique epigenomic phenotypes. Nonetheless, 5-azacitidine, which inhibits DNA methyltransferase activity, is not efficacious in BRAFV600E colorectal cancer in vivo.

Experimental design: We randomized and treated mice implanted with patient-derived tumor xenografts harboring BRAFV600E mutation with control, 5-azacitidine, vemurafenib (BRAF inhibitor), or the combination. Comprehensive epigenomic profiling was conducted on control and 5-azacitidine-treated tumor samples, including DNA methylation, histone modifications, chromatin accessibility, and gene expression. Combinations of epigenetic agents were explored in preclinical BRAFV600E colorectal cancer models.

Results: A profound reduction of DNA …

Optimization Processes Of Clinical Chelation-Based Radiopharmaceuticals For Pathway-Directed Targeted Radionuclide Therapy In Oncology, Katsumi Tomiyoshi, Lydia J. Wilson, Firas Mourtada, Jennifer Sims Mourtada, Yuta Namiki, Wataru Kamata, David J. Yang, Tomio Inoue

Department of Radiation Oncology Faculty Papers

Targeted radionuclide therapy (TRT) for internal pathway-directed treatment is a game changer for precision medicine. TRT improves tumor control while minimizing damage to healthy tissue and extends the survival for patients with cancer. The application of theranostic-paired TRT along with cellular phenotype and genotype correlative analysis has the potential for malignant disease management. Chelation chemistry is essential for the development of theranostic-paired radiopharmaceuticals for TRT. Among image-guided TRT,

Administrators’ Perception Of Successful Implementation Of Read To Succeed In Title I Schools, Angela Sandifer Flowers

Walden Dissertations and Doctoral Studies

South Carolina implemented its Read to Succeed (RTS) policy in 2014 in accordance with federal requirements. The problem addressed in this study was that there are many students in South Carolina Title I schools still failing to achieve reading proficiency after 3 years of full implementation of RTS. The purpose of this qualitative study was to explore the perceptions of administrators from successful Title I elementary schools on their roles in the change process needed for implementing RTS. The conceptual framework was Fullan’s change theory. For this basic qualitative design, data were collected from semistructured interviews with seven participants who …

Butte Priority Soils Operable Unit, Butte Reclamation Evaluation System Draft 2024 Field Evaluation Of Previously Reclaimed Sites Summary And Technical Recommendations Report, Butte-Silver Bow Department Of Reclamation And Environmental Services

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Low-Molecular Weight Cyclin E Confers A Vulnerability To Pkmyt1 Inhibition In Triple-Negative Breast Cancer, Mi Li, Amriti R Lulla, Yan Wang, Spyros Tsavaschidis, Fuchenchu Wang, Cansu Karakas, Tuyen D T Nguyen, Tuyen N Bui, Marc A Pina, Mei-Kuang Chen, Sofia Mastoraki, Asha S Multani, Natalie W Fowlkes, Aysegul Sahin, C Gary Marshall, Kelly K Hunt, Khandan Keyomarsi

Faculty, Staff and Student Publications

Cyclin E is a regulatory subunit of CDK2 that mediates S phase entry and progression. The cleavage of full-length cyclin E (FL-cycE) to low-molecular weight isoforms (LMW-E) dramatically alters substrate specificity, promoting G1-S cell cycle transition and accelerating mitotic exit. Approximately 70% of triple-negative breast cancers (TNBC) express LMW-E, which correlates with poor prognosis. PKMYT1 also plays an important role in mitosis by inhibiting CDK1 to block premature mitotic entry, suggesting it could be a therapeutic target in TNBC expressing LMW-E. In this study, analysis of tumor samples of patients with TNBC revealed that coexpression of LMW-E and PKMYT1-catalyzed CDK1 …

What Do Cancer Genetic Providers Want Us To Know About Variant Reclassification And Recontact That We Are Not Asking? A Thematic Analysis Of Open-Ended Survey Responses, Kerri Brown, Marisel Ponton, Elenita Davidson, Banu Arun, Robert J Volk, Sanjay Shete, Susan K Peterson, Sukh Makhnoon

Faculty, Staff and Student Publications

BACKGROUND: Accurate variant classification and relaying reclassified results to patients is critical for hereditary cancer care delivery. Over a 5- to 10-year period, 6%-15% of variants undergo reclassification. As the frequency of reclassifications increases, the issue of whether, how, when, and which providers should recontact patients becomes important but remains contentious.

METHODS: The authors used inductive thematic analysis to analyze open-ended comments offered by oncologists and genetic counselors (GCs) from a large national survey.

RESULTS: Of the 634 oncologists and cancer GCs, 126 (20%) offered substantive free-text comments. Four thematic areas emerged: 1) ambiguity over professional responsibility to recontact, 2) …

The Effect Of Interruptions In Surgical Counts, Jaidin Degraw, Brooke Gisel

Nursing Research and EBP Day 2024

Retained surgical items can lead to patient frustration and prolonged hospital stays. They remain the top reason for reoperation despite the tools that are used to maintain accurate counts. Minimizing disruptions and distractions in the operating room may be one way to assist circulating nurses in obtaining correct and consistent counts.

Navigating The Paradox Between Professional Challenges And Teacher Well-Being: The Role Of Strategies Within The Resilience Process, Isabelle Krummenacher, Tina Hascher, Caroline Mansfield, Susan Beltman, Julia Mori, Irene Guidon

Research outputs 2022 to 2026

Teaching is an immensely complex profession that often requires managing multiple and varied professional challenges. Despite these challenges, teachers tend to report moderate to high levels of well-being. This qualitative study explored this paradox by investigating the professional challenges reported and the coping strategies Swiss teachers use to support their well-being. Relational problem-solving was identified as a commonly used strategy when professional challenges occur. The unique contribution of this study lies in its further elucidation of the complex relationship between teachers’ professional challenges and well-being embedded in a resilience process. The results of this study provide implications for understanding how …

Re: Comment Letter For Bpsou Draft Phase I Design Investigation Evaluation Report (Dated September 25, 2024), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Ultra-Relativistic Electron Flux Enhancement Under Persistent High Speed Solar Wind Stream, L R. Alves, L A. Da Silva, V Deggeroni, J P. Marchezi, P R. Jauer, G B D Silva, D G. Sibeck

Faculty Publications

The physical mechanisms usually applied to explain the relativistic electron enhancement have been delved into to elucidate non-adiabatic electron acceleration resulting in the ultra-relativistic electron population observed in the outer radiation belt. We considered multisatellite observations of the solar wind parameters, magnetospheric waves, and particle flux to report an unusual local acceleration of ultra-relativistic electrons under a prolonged high-speed solar wind stream (HSS). A corotating interaction region reaches the Earth’s bowshock on August 3, 2016, causing a minor geomagnetic storm. Following this, the magnetosphere was driven for 72 h by a long-term HSS propagating at 600 km/s. During this period, …

Lung Tissue Multilayer Network Analysis Uncovers The Molecular Heterogeneity Of Chronic Obstructive Pulmonary Disease, Nuria Olvera, Jon Sánchez-Valle, Iker Núñez-Carpintero, Joselyn Rojas-Quintero, Guillaume Noell, Sandra Casas-Recasens, Alen Faiz, Philip Hansbro, Angela Guirao, Rosalba Lepore, Davide Cirillo, Alvar Agustí, Francesca Polverino, Alfonso Valencia, Rosa Faner

Faculty, Staff and Students Publications

Rationale: Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition. Objectives: We hypothesized that the unbiased integration of different COPD lung omics using a novel multilayer approach might unravel mechanisms associated with clinical characteristics.

Methods: We profiled mRNA, microRNA and methylome in lung tissue samples from 135 former smokers with COPD. For each omic (layer), we built a patient network on the basis of molecular similarity. The three networks were used to build a multilayer network, and optimization of multiplex modularity was used to identify patient communities across the three distinct layers. Uncovered communities were related to clinical features.

Measurements …

Factors That Influence Colostrum Yield: Dry Period Length, Peter S. Erickson

UNH Cooperative Extension

No abstract provided.

Re: Comment Letter For Draft Clark Tailings Consolidated Waste Management Area (Ctcwma) Site Investigation Draft Data Summary Report 2019-2023 (Dated October 3, 2024), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Evaluating The Effectiveness Of Edge Line Sinusoidal Rumble Strips On Lane Departure Crash Prevention And Injury Severity, Shubhankar Chintamani Shindgikar

USF Tampa Graduate Theses and Dissertations

Lane departure crashes are one of the most prevalent accidents in Florida and the United States. Various forms of rumble strips have been employed to mitigate and decrease these incidents. The Florida Department of Transportation (FDOT) recently adopted a new sinusoidal rumble strip pattern for statewide implementation of audible and vibratory treatment (AVT). Recent research indicates sinusoidal rumble strips are highly effective in alerting drivers audibly and through tactile vibrations, thus aiding lane departure prevention. Moreover, they generate less external noise compared to other rumble strip textures.

However, a systematic assessment of the safety effectiveness of sinusoidal rumble strips in …

Spatiotemporal Dynamics Of Coastal Nekton Metacommunities In The Western Atlantic, Jonathan A. Peake

USF Tampa Graduate Theses and Dissertations

The processes of diversification, selection, dispersal, and stochastic drift can combine in many ways to assemble ecological communities. A key focus in ecology is to describe and quantify the relative influences of these processes for different systems and explain the mechanisms by which these processes produce patterns of community structure. To accomplish this goal, ecologists have developed several frameworks that seek to integrate processes that occur locally andregionally. The metacommunity concept treats local communities as pieces of a broader landscape that are connected through dispersal of their constituent organisms. Empirical studies have generally lagged behind the development of metacommunity theory. …

Comment Letter For Bpsou Draft Phase I Design Investigation Evaluation Report (Dated September 25, 2024), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.