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Communicating The “Already, Not Yet” Through The Visual Arts, Hadley Jacobs

Senior Honors Theses

The “already, not yet” is a theological concept that addresses the tension of Christian living. Although believers are free from sin’s power, they are not free from its effects. This thesis examines the “already, not yet” through a series: one graphite drawing, one colored pencil drawing, and one oil painting. The graphite drawing depicts a ruined building, the colored pencil drawing depicts a building being rebuilt, and the oil painting depicts a restored building. They represent the fallen state of man, the state of believers on earth, and the state of believers after being restored, respectively. Together, these pieces create …

Chemoproteomic Profiling Of A Carbon-Stabilized Gold(Iii) Macrocycle Reveals Cellular Engagement With Hmox2, Sailajah Gukathasan, Chibuzor Ngozi Olelewe, Libby Ratliff, Jong H. Kim, Alyson M. Ackerman, J. Robert Mccorkle, Sean Parkin, Gunnar F. Kwakye, Jill M. Kolesar, Samuel G. Awuah

Chemistry Faculty Publications

In this work, we discovered a novel organometallic gold(III) macrocycle, Au-Mac1, that demonstrates anticancer potency in a panel of triple-negative breast cancer cells (TNBC), and based on this complex, a biotinylated-Au-Mac1 probe was designed for target identification via chemoproteomics, which uncovered the engagement of HMOX2 of the heme-energy metabolism pathway. Using orthogonal chemical biology and molecular biology approaches, including immunoblotting, flow cytometry, and cellular thermal shift assays, it was confirmed that Au-Mac1 engages HMOX2 in cells. Downstream effects of Au-Mac1 on the depletion of mitochondrial membrane proteins and bioenergetics point to the potential role of HMOX2 in cancer. Importantly, Au-Mac1 …

Iodinated Disinfection Byproduct Formation From Iohexol In Sunlit And Chlorinated Urban Wastewaters, Reagan Patton Witt, Marcelo I. Guzman

Chemistry Faculty Publications

Iodinated disinfection by-products (I-DBPs) are of growing concern due to their elevated toxicity compared to their chlorinated counterparts, with links to adverse health effects such as bladder cancer and miscarriages. Medical imaging agents like iohexol, commonly used in healthcare facilities, introduce iodine into wastewater systems. This study investigates the photodegradation of iohexol and the subsequent formation of products, including I-DBPs, during simulated final wastewater treatment under chlorination and sunlight exposure. Experiments were conducted with solutions containing 30 μM iohexol, 3 mg L⁻¹ humic acids, and 5.5 mg L⁻¹ hypochlorite. Samples were irradiated at λ ≥ 295 nm and …

Improving Proteostasis Of Trafficking-Deficient GabaAReceptor Variants By Activating Ire1, Xu Fu, Ya Juan Wang, Kyung A. Lee, Lucie Y. Ahn, Xi Chen, Brock T. Harvey, Meng Wang, Hailey Seibert, Pei Pei Zhang, Adrian Guerrero, Ashleigh E. Schaffer, Christopher I. Richards, R. Luke Wiseman, Jeffery W. Kelly, Ting Wei Mu

Chemistry Faculty Publications

Gamma-aminobutyric acid type A receptors (GABA_ARs) are essential for maintaining the excitation–inhibition balance in the central nervous system. Genetic variations of GABA_ARs result in a variety of neurological disorders, such as epilepsy. A key pathogenic mechanism involves protein misfolding and defective assembly of GABA_ARs in the endoplasmic reticulum (ER), resulting in impaired surface expression and loss of function. Here, we investigated three trafficking-deficient variants of the GABA_AR α1 subunit (GABRA1), including D219N (ClinVar Variation ID: 127232), G251D (Variation ID: 419523), and P260L. We demonstrated that selective pharmacological activation of the IRE1/XBP1s signaling …

Machine Learning Approaches For Predicting Breast Cancer Recurrence: A Comparative Analysis, Noor Razzaq Abbas, Hussein Alkattan, Isam Bahaa Aldallal

Mesopotamian Journal of Artificial Intelligence in Healthcare

This paper reports a comparative analysis of four supervised machine learning algorithms: RF, SVM (using radial and linear kernels), Logistic Regression, and Multi-Layer Perceptron, for breast cancer recurrence prediction on a carefully curated clinical dataset. The data set, first collected by Royston and Altman and subsequently released on Kaggle, has patient age, menopausal status, tumor size, histological grade, lymph node status, estrogen and progesterone receptor levels, hormone therapy for treatment, recurrence-free survival time, and a binary recurrence outcome. The data set was then divided after the elimination of identifiers and z-score normalization in an 80:20 ratio using stratified sampling. Models …

Satellite And Uas Synergy For Large-Scale Crop Canopy Cover Mapping With Deep Learning, Muhammad Ali Irshad

Electronic Theses and Dissertations

No abstract provided.

Poison! An Africana Legal Studies Investigation Into Enslaved Africans And Their Deadly Roots, Angi Porter

Minnesota Journal of Law & Inequality

No abstract provided.

Machine Learning-Guided Discovery Of Metal-Ligand Catalysts For Affordable Green Hydrogen Produced Via Proton Exchange Membrane Electrolyzers, Achouak Benarbia

Theses and Dissertations

The rising demand for clean and sustainable energy sources has underscored the critical role of hydrogen in the global energy transition. However, the widespread adoption of green hydrogen remains constrained by the high cost and scarcity of platinum-based electrocatalysts used in Proton Exchange Membrane (PEM) electrolyzers. This dependence inflates production costs and poses long-term risks related to supply security and scalability. While numerous studies have explored alternative materials, the discovery of efficient and stable non-platinum catalysts remains a major bottleneck due to the vastness of chemical space and the resource-intensive nature of experimental screening. To address this challenge, this study …

A Modern Optimization Approach With Data-Driven Analytical Modeling For The Healthcare Business Segment (Hbs) From The S&P 500, Aditya Chakraborty, Chris Tsokos

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Introduction: The S&P consists of eleven business segments, which are classified according to the type of industry. The current study focuses on developing a non-linear analytical model for the Healthcare Business Segment (HBS) of the S&P 500, as a function of different economic & financial indicators. Materials and Methods: The analytical model used six financial indicators together with four economic indicators to predict the weekly average closing price (WCP) of HBS stocks. Johnson’s SB transformation corrected skewness, while desirability-based optimization identified indicator values maximizing WCP. The model’s performance and generalizability were validated through repeated 10-fold cross-validation. Results: All attributable contributors …

The Caseload Chronicles: Investigating The Case Manager Role Through The Perspectives Of Current Special Education Teachers, Khalil Milad Abouhamad

University of the Pacific Theses and Dissertations

Teacher attrition and resulting shortages have become severely problematic across the United States. This is especially true within special education. This study employs role theory (Kahn et al., 1964) to isolate the case manager role carried by special education teachers, investigate it through the stories of current practitioners, and establish it within academia. Burnout theory (Maslach, 1993) provides a lens through which to evaluate the strain of working conditions surrounding the case manager role. Elements of narrative inquiry (Clandinin, 2006; Creswell & Guetterman, 2019) in the form of 1-1 interviews with current IEP case managers from across California provided the …

Understanding Self-Efficacy And Motivation In Elementary Teachers: The Influence And Support Of School Administrators, Maria Vigil

University of the Pacific Theses and Dissertations

Teachers’ attrition is commonly seen within the first five years in the profession. Various reasons exist as the cause for this decision including: low pay rates, lack of support and stress. With the important role educators hold, a clear understanding of their specific needs can help strengthen their abilities while remaining in the field. The purpose of this mixed methods study was to understand teachers’ perspectives of what influences their self-efficacy and motivation in order to promote strong work performance, effectiveness, increase teacher satisfaction and retention rates while highlighting the impact of support provided by school administrators. The research questions …

From Street Codes To School Codes: Transformative Educational Intervention For Gang Affiliated Student. An Active Research Study, Alexandra Saldivar

University of the Pacific Theses and Dissertations

Gang-affiliated youth face significant challenges in educational and community settings, often resulting in lower graduation rates, limited career opportunities, and an increased risk for behavioral problems. While gang activity on school campuses has increased in recent years, there is limited research and little effort specifically tailored to meet the needs of this vulnerable population. This study aims to evaluate the effectiveness of the WhyTry intervention, a resilience-focused program designed for at-risk populations, modified with additional counseling and a gang-intervention emphasis to address the unique challenges gang-affiliated students face. The study explores whether the modified WhyTry program can improve academic performance, …

A Look Into A Great Coach: Qualitative Study Of Post-Game Talks Of A Highly Successful Volleyball Collegiate Coach, Daniel Nobuo Llarenas

University of the Pacific Theses and Dissertations

The primary purpose of this study was to explore the post-game talks of a highly successful collegiate coach. A total of 19 post game talks were audio recorded during the 2012 championship season of the University of California Irvine (UCI) Men’s Volleyball team. Coach John Speraw; an American Caucasian Division I Men’s Collegiate Volleyball coach and was the Head coach during the 2012 season. Post game talks were recorded with intentions of assessing content and transcribed verbatim with the average length of each talk was 7 minutes and 23 seconds (4:36 – 23:04 mins). Analyses of the transcripts revealed 2 …

The Comstock Act’S Equal Protection Problem, Danny Y. Li

Michigan Law Review Online

Following its victory in Dobbs, the antiabortion movement has set its sights on a national abortion ban. Affiliates of the second Trump Admin- istration—including the vice president-elect—have endorsed the re- newed enforcement of the 1873 Comstock Act as one avenue for implementing such a ban. This Essay argues that contemporary enforce- ment of the Comstock Act as a national abortion ban would be unconsti- tutional. The Act violates the Fifth Amendment’s equal protection guarantee because it was enacted with the discriminatory purpose of in- hibiting illicit sex to promote women’s sexual purity. Only contemporary reenactment of the law without constitutionally …

Exploring The Perceived Impact Of Hearing Impairment On The Mental Health And Well-Being Of Adults, Jacinta Ruth Marks

Theses

This thesis explores the perceived impact of hearing impairment on the mental health and well-being of Australian adults, responding to a growing need to understand how hearing challenges affect people beyond clinical or audiological measures. While hearing impairment is commonly framed through medical or functional models, its psychosocial effects remain underexplored, particularly in relation to stigma, identity, and mental well-being. This study addresses that gap by centring lived experience and examining how adults with hearing impairment navigate everyday life, social expectations, and systemic barriers. Grounded in a constructivist-interpretivist paradigm and informed by a disability studies lens, the research investigates the …

Estimating The Gender Wage Gap: A Comparative Analysis Of Different Estimators, Xinran Zhang

Mathematics, Statistics, and Computer Science Honors Projects

The gender wage gap between males and females has been well studied by labor economists. We take a multi-prong approach to evaluate three estimators —a regression-imputation estimator, a weighting estimator, and a doubly robust estimator—in estimating the gender wage gap. Using the Panel Study of Income Dynamics, we conduct an empirical study of the estimators’ performances. In a simulation study, we evaluate the properties of estimators and study whether bootstrapping is an appropriate measure of the uncertainty of each estimator. The findings show that while the estimators provide different results, the doubly robust estimator provides reliable and consistent results under …

Leveraging Deep Learning For The Automated Detection Of Hemophilic Arthropathy In Knee Radiographs, En-Wei Lin, Edzer Wu, Ming-Ching Shen, Shao-Li Han

Rehabilitation Practice and Science

Background/Purpose:

Hemophilic arthropathy (HA) is a progressive joint disease caused by recurrent hemarthroses in patients with hemophilia. Early radiographic identification of HA is critical for timely intervention and long-term joint preservation. This study aimed to develop and evaluate deep learning models for automated detection of HA in knee radiographs.

Methods:

A retrospective dataset of 849 knee radiographs (AP and lateral views) was used to train three convolutional neural networks: ResNet-34, DenseNet-121, and EfficientNet-B0. Model performance was assessed using standard classification metrics, including accuracy, precision, recall, F1-score, and AUC. Interpretability was evaluated using Grad-CAM heatmaps.

Results:

DenseNet-121 achieved balanced performance on …

Building Diversity Into The Philosophy And Methodology Of Economics With Stratification Economics, Merve Burnazoglu, John B. Davis

Economics Faculty Research and Publications

Mainstream economics ignores who produces it and what it is about because its average man, Homo economicus ontological entry-point obscures social differences between people. Philosophy and Methodology of Economics that assumes this ontological entry point generally limits itself to epistemological analysis, and this means it fails to make diversity a fundamental concern. Taking diversity seriously entails being clear about one's ontological assumptions, and this requires being clear about the normative scope of one's analysis. This calls for giving up a value-neutral methodological reasoning and adopting a value-explicit methodological posture. To illustrate, we describe how Stratification economics with its social groups …

Giant Cane (Arundinaria Gigantea) And The Swainson’S Warbler (Limnothlypis Swainsonii): Implementing Innovative Monitoring Techniques For Species Of Conservation Concern, Gabriela Carroll

Graduate Theses/Dissertations

In the U.S., following colonization and agricultural expansion, giant cane (Arundinaria gigantea) has been reduced to approximately 2% of its original extent, potentially causing shifts in the abundance and distribution of over 70 associated animal species. Among those species is the Swainson’s Warbler (Limnothlypis swainsonii), which has been known to occupy canebrakes during the breeding season. Though there is little known about the historical range of the Swainson’s Warbler and its current population status, some have hypothesized that its population may have declined due to the reduction of its suitable breeding habitat. As this species is …

Optical Properties Of Rare Earth Doped Molybdenum Trioxide Thin Films, Jessica Fink

Graduate Theses/Dissertations

This study aims to investigate the optical properties of Dy-doped MoO₃ thin films. MoO₃ is a transition metal oxide that is wide band gap semiconductor. As a transition-metal oxide, it has been widely studied for its tunable properties. However, there is little literature on the subject of Dysprosium doped MoO₃, and none found as of now on thin film Dy-MoO₃ . This indicates that this topic is at best under reported, and thin film Dy-MoO₃ possesses a certain novelty. Unlike most transition metal oxides, undoped MoO₃ has a negligible crystal field splitting. This is due to the electron vacancy of …

Correlates Of Gacha Gaming, Minh Quang Nguyen

Graduate Theses/Dissertations

The purpose of this study was to explore the relationship between impulsive measures, income spending on gaming, and delayed discounting in a Gatha player sample. Two model approaches were employed: (1) a mediation model approach predicting delayed discounting with age and education level as mediators and (2) a multiple regression model predicting delayed discounting. Although the proposed models were exploratory, it was the contention of the author that these analyses would result in a better understanding of delayed discounting in Gacha gaming. Both age and education level were not correlated with the dependent variable (spending ratio), therefore the mediation model …

Tailwater Trout Population Dynamics, Connor Dylan Cunningham

Graduate Theses/Dissertations

Dams have been constructed throughout the world and provide several resources for humans (e.g., flood control, hydropower). These structures heavily alter the upstream and downstream environment. One consequence of these alterations is the creation of “tailwaters”, which can create cold-water habitat via hypolimnetic releases. In the southeast United States these tailwater environments are often managed for the recreational use of nonnative salmonids. The unnatural flow regimes of tailwaters affect the biotic and abiotic conditions and ultimately the dynamic rate functions (i.e., recruitment, growth, mortality) of the fish inhabiting them. As such, the goal of this research is to provide fisheries …

The Effect Of Hypochlorous Acid On Cultured Osteoblast And Escherichia Coli, Cristina Flaquer Fusté

Graduate Theses/Dissertations

Hypochlorous acid (HOCl), a naturally occurring compound in neutrophils, has been used as an antimicrobial in wound treatment. Osteoblasts, bone-forming cells, within the bone tissue play a large role in bone fracture healing. Orthopedic infections are challenging to treat and highly morbid, including surgical site infection of arthroplasty procedures or infection in the setting of compound fractures. HOCl is being considered as a surgical antiseptic to decrease infections in orthopedic surgical procedures. This study therefore seeks to determine the effects of HOCl on osteoblasts and E. coli. Cultured osteoblasts were incubated with varying concentrations of HOCl to examine osteoblast …

"See How He Loved Him": Lazarus Of Bethany As The Beloved Disciple In The Gospel Of John, Jared M. Pannell

Graduate Theses/Dissertations

Traditionally, the “disciple whom Jesus loved” from the fourth of the Christian gospels has been identified as John the Apostle, one of the original twelve disciples of Jesus, since at least the late second century. In recent scholarship, however, this position has come increasingly under question. Questions of John the Apostle’s literacy and capacity to write the gospel and doubts about the veracity of the eyewitness claims in the gospel have shifted the landscape of scholarly inquiry. As such, a wide variety of alternative candidates have been proposed. This thesis puts forward Lazarus of Bethany as a serious candidate for …

Utilizing The Spatial Evaluation Of Language And Flexibility For Youth (Self-Y) In Clinical Case Conceptualization, Katelyn Frahm

Graduate Theses/Dissertations

Individuals diagnosed with autism spectrum disorder (ASD) often experience challenges with restricted and repetitive behaviors, relating directly to challenges with psychological flexibility (Hyman et al., 2020; Hayes et al., 2006). Unfortunately, the history of applied behavior analysis has extended harmful implications of treatment that have focused on compliance training and punishment, often worsening psychological flexibility (Sandoval-Norton et al., 2019). Research is calling behavior analysis to combine flexible approaches, such as Acceptance and Commitment Therapy, with technologies exploring the intricacies of individual relational networks (Hayes et al., 1999; Hayes et al., 2022; Hayes & King, 2024). The present study introduced the …

Characterization Of The Overexpression Of Reca Homologs Rad51 And Dmc1 In Tetrahymena Thermophila, Jianna M. Cox

Graduate Theses/Dissertations

RecA homologs, Dmc1 and Rad51, work to repair DNA double-strand breaks (DSBs) within the cell through the recombination of homologous sections of DNA. Dmc1 works to repair programmed DSBs through meiotic recombination, while Rad51 functions to repair both meiotic and non-meiotic DSBs, the latter repaired through the process of homologous recombination repair (HHR). Chemotherapeutics, exogenous agents, work to form DSBs in cancer cells, attempting to inhibit the cell’s growth. A hyper recombinant phenotype is often seen in cancer cells due to the overexpression of RAD51, leading to drug resistance, the persistence of cancers, and an overall poor patient outcome. …

Synthesis And Characterization Of Doped Rare-Earth Zinc Alloys, Partha Das

Graduate Theses/Dissertations

Rare-Earth-Zinc (RE-Zn) alloys doped with manganese represent a promising class of materials with diverse applications in magnetic, electronic, and thermoelectric devices. These alloys hold significant potential owing to the unique combination of rare-earth elements' properties with the versatility of zinc, augmented by manganese doping. In this study, I present the successful synthesis of ErMn_0.2Zn_11.8 alloys, achieved through self-flux method. The synthesized crystals were characterized using electron dispersive spectroscopy (EDS) and single crystal X-ray diffraction (XRD). Additionally, magnetic measurements were performed to investigate the magnetic properties. Future plans include DFT calculations and comparison study between Rare-Earth-Zinc alloys with …

Responses Of Native And Invasive Aquatic Vegetation To Changes In Water Depth In An Ozark Spring-Fed Pond, Daphne Miles

Graduate Theses/Dissertations

Spring-fed aquatic ecosystems in the Ozark Highlands are characterized by stable water depths, clear water, and diverse aquatic vegetation (filamentous algae, submerged, floating, and emergent plants). Sudden changes in water depth can impact aquatic vegetation dynamics but the impacts of prolonged changes are poorly understood. I investigated seasonal and annual changes to aquatic vegetation abundance in a spring impoundment during and after a two-year period of low water depth that was caused by a broken outlet below an artificial dam. Water depth was significantly lower in 2020 and 2021 (low water years), compared to 2022 and 2023 (high water years). …

2025-2026, Benjamin N. Cardozo School Of Law

Student Handbooks

No abstract provided.

Teacher Moves For Building A Mathematical Modeling Classroom Community, Ayse Ozturk

Teaching & Learning Faculty Publications

This study investigates the role of teacher talk moves in cultivating a mathematical modeling classroom community. From the models and modeling perspective, it explores how specific teacher talk moves promote student participation in modeling phases and the exchange of ideas with other students. Through a four-week after-school program involving eight secondary students, data were collected from small-group and whole-class discussions. The findings reveal that teacher talk moves can be categorized into three core types: eliciting students’ ideas, introducing key terms and ideas used in mathematical modeling, and encouraging students to take a position during discussions. These moves are shown to …