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Associations Between Five-Year Blood Pressure Variability And Risk Of Cardiovascular Events And Mortality: A Territory-Wide Family Medicine Cohort Study, Jiandong Zhou, Sharen Lee, Wing Tak Wong, Keith Sai Kit Leung, Wai Kit Ming, Tong Liu, Kamalan Jeevaratnam, Bernard Man Yung Cheung, Gary Tse, Qingpeng Zhang

Journal of the Hong Kong College of Cardiology

Introduction: Blood pressure variability, in addition to blood pressure itself, has been used as a predictor for mortality. This study examined the predictive power of baseline/latest/mean/median blood pressure and blood pressure variability measures for all-cause mortality and adverse cardiovascular outcomes.

Methods: The retrospective observational study analyzed patients who presented to family medicine clinics between 1^st January, 2000 and 31^st December, 2001. Blood pressure measurements were obtained over a five-year period. Standard deviation (SD), root mean square (RMS), coefficient of variation (CV) and a variability score (number of >=5 mmHg blood pressure change) were used as measures of blood …

Challenges Faced In Managing The Hemodynamic Status Due To Recurrent Gastrointestinal Bleeding In Typhoid Fever With Uncorrected Double Outlet Right Ventricle Patient: A Case Report, Kellyn Trycia Zenjaya, Lindawati Wijoyo, Jovan Amadeo Muliyanto, Rizqi Rokhmadhoni Pikir, Dwi Putri Lestari, Esthy Poespitaningtyas

Journal of the Hong Kong College of Cardiology

Double Outlet Right Ventricle (DORV) is a rare cyanotic congenital heart defect often associated with polycythemia and bleeding risk. A 7-year-old boy with uncorrected DORV presented with fever, melena, and shock. He was cyanotic, tachypneic, and tachycardic, with SpO₂ of 68% and a harsh ejection systolic murmur. Labs showed anemia, thrombocytopenia, leukocytosis, and prolonged APTT. Tubex TF IgM was strongly positive. A diagnosis of typhoid fever with gastrointestinal bleeding and uncorrected DORV was made. Management included oxygen, inotropes, and fluid resuscitation. Propranolol was withheld. Severe infection with underlying cyanotic heart disease and coagulopathy presents a critical management dilemma.

An Unusual Cause Of Acute Constrictive Pericarditis, Yue Hin Tang, Raymond Chi Yan Fung

Journal of the Hong Kong College of Cardiology

Constrictive pericarditis, a condition where the pericardium thickens and constricts, has long been considered as a chronic sequela of prior insults to the pericardium such as heart surgery, repeated pericarditis, tuberculosis infection, radiation exposure, etc. Susceptible populations are thus expected to be middle-aged.

We present a case in which a young gentleman was diagnosed with acute constrictive pericarditis due to Adult-onset Still’s disease with macrophage activation syndrome. This case illustrated that constrictive pericarditis could happen in acute settings and thus the importance of cardiologists to maintain open-minded in search of a diagnosis

Collateral Damage: Dual Mechanical Complications From An Apparently Small Myocardial Infarction, Irene Carrión-Sánchez, Luis Manuel García-Linacero, Paola Ramos-Cano, Jesús Ducay-Rico, Ana Pardo-Sanz, Diego Matellán-Alonso, Irene Gámez-Guijarro, Marcelo Sanmartín, José L. Zamorano

Journal of the Hong Kong College of Cardiology

We report a rare case of myocardial infarction complicated by anterolateral papillary muscle rupture and right ventricular infarction in a 49-year-old man. Initial signs suggested pulmonary embolism, but imaging revealed inferolateral infarction with right ventricular involvement. Angiography showed a thrombosed obtuse marginal branch supplying a chronically occluded right coronary artery. Despite intervention, the patient developed refractory cardiogenic shock. Surgery revealed complete papillary muscle rupture; mitral valve replacement and bypass were performed, but the patient died postoperatively. This case highlights the fatal potential of uncommon infarction patterns and the limited success of surgery, emphasizing the need for alternative transcatheter strategies in …

University Of San Diego Graduate Course Catalog 2025-2026, University Of San Diego

Graduate Course Catalogs (1971-)

649 pages

Systm. Haciendo Visibles Los Cuerpos Invisibles (2025), Natalia Guillén Rodríguez

Grado en Diseño de Moda

Este Trabajo de Fin de Grado investiga cómo la moda ha contribuido a invisibilizar los cuerpos no normativos a través de la imposición de estándares estéticos excluyentes. Lejos de ser neutra, la moda ha operado como una herramienta de violencia simbólica, definiendo qué cuerpos merecen ser vistos y cuáles deben ser corregidos, tapados o ignorados.

Se analiza el impacto que estos ideales han tenido en la salud mental, especialmente en las mujeres, reforzando dinámicas de exclusión y jerarquías corporales que siguen vigentes, aunque ahora vengan disfrazadas de “diversidad”. También se cuestiona la autenticidad del discurso inclusivo dentro de la industria, …

Empty Voting And Hidden Ownership In Canadian Jurisprudence, Maziar Peihani

All Faculty Publications

The classic understanding of equity encompasses a suite of economic and governance rights, which typically includes the rights to vote, receive dividends, and participate in distribution of assets upon dissolution. This conventional view, outlined in corporate legislations, is supported by Canadian jurisprudence and corporate law scholarship. However, financial innovations have facilitated the separation of voting rights from the financial entitlements of shares, creating a marketplace where shareholder interests are reconfigured and traded in diverse ways. Derivatives and securities lending arrangements have led to phenomena known as empty voting and hidden ownership. In empty voting, an investor retains voting rights without …

Realities Of Nutrition, Judi S. Morrill

Open Educational Resources

What Is Nutrition Reality? Is it in the advertising claims that a food is natural or supplies instant energy? Is it in the myriad of dietary supplements? Is it in the diet plans for instant weight loss and glowing health? The only way to find out is to learn the basic principles of nutrition science, so you can be your own nutrition expert. Here is the true introduction to nutrition that you will read with pleasure and real understanding. It will free you from dependence on popular sources of information - often misinformation - so you can distinguish illusion from …

Words And Stardom: Modernist Poetic Responses To Asta Nielsen, Karl E. Toepfer

Open Educational Resources

This essay discusses how four modernist poets portrayed the Danish movie star Asta Nilesen (1881-1972). German Hans Schiebelhuth (1895-1944) describes the "demonic" power of Nielsen's image to awaken dark aspects of his adolscent personality. For the Flemish poet Paul van Ostaijen (1896-1928), Nielsen's cinematic image provokes a radical shattering of language into extravagant "word-images." Danish writer Rudolf Broby-Johansen (1900-1987) linked Nielsen's image to a radical (Marxist) critique of oppressive sexual politics within a capitalist society. German Franz Behrens (1895-1977) composed a lengthy, expressionist ode to Nielsen from the perspective of one who actually worked as a screenwriter in the German …

A Place To Talk About Family Change: A Guide To Creating An Affinity Space For Children Of Divorce, Eliza Kissick

Graduate Student Independent Studies

This independent study includes a rationale, a review of relevant related research, and a nine-session affinity space curriculum designed for children ages 6–8 who are navigating family changes such as divorce, separation, and blending.

Drop Dynamics During Condensation On Superhydrophobic Surfaces In Vapor Shear Flow, Shaur Humayun, R. Daniel Maynes, Julie Crockett, Brian D. Iverson

Faculty Publications

Accurate models for predicting drop dynamics, such as maximum drop departure sizes, are crucial for estimating heat transfer rates during condensation on superhydrophobic (SH) surfaces. Previous studies have focused on examining the heat transfer rates for SH surfaces under the influence of gravity or vapor flowing over the surface. This study investigates the impact of surface solid fraction and texture scale on drop mobility in a condensing environment with a humid air flow. Experiments recorded condensation with varying surface feature sizes from micro- to nano scale under different flow rates. Video analysis detected the drop-size distribution and maximum drop departure …

Association Between Neighborhood-Level Social Vulnerability And Hypertension Outcomes, John E. Brush Jr., Chungsoo Kim, Yuntian Liu, Xin Xin, Chenxi Huang, Iris J. Lundy, Jordan R. Asher, Mitsuaki Sawano, Patrick Young, Jacob Mcpadden, Mark Anderson, John S. Burrows, Harlan M. Krumholz, Yuan Lu

Department of Medicine Faculty Publications

Background

Neighborhood-level social vulnerability is associated with hypertension prevalence and severity and with cardiovascular complications in conditions other than hypertension, but its association with cardiovascular complications in patients with hypertension is understudied.

Objectives

The aim of the study was to examine how the neighborhood-level social vulnerability index (SVI) influences cardiovascular outcomes in a large, diverse cohort of patients with hypertension.

Methods

We used electronic health data to examine the association between census tract-level rankings for the SVI with a composite endpoint of incident myocardial infarction, congestive heart failure, or stroke.

Results

In a longitudinal cohort of 330,972 patients with hypertension …

Project Manager Risk Response Via The Schedule Duration Mechanism In New Product Development, James S. Bryant

Open Access Dissertations

This experimental study investigated the relationship between project risk level and forecasted project schedule duration. Grounded within a systematic literature review, the research is motivated by the continuing high failure rate for new product development (NPD) projects to meet their time objectives. U.S.-based project managers (PMs) were given a project network diagram, assigned to one of four experimental groups (each group also receiving varying information regarding project risks), and asked to forecast the most likely schedule duration from start to finish. The data suggest that there is no correlation between the level of project risk and the forecasted duration and …

Incentives, Performance Metrics, And Healthcare Supply Chain Waste, Sharon Ann Franzetta

Open Access Dissertations

Healthcare spending in the United States (US) is increasing at a rate higher than the US gross domestic product while the demand for healthcare services is simultaneously increasing. With supply costs posing as the second highest cost in hospital expenditures, reducing supply expenses by means of eliminating supply management waste could potentially reduce overall healthcare costs. Supported by evidence found through three manuscript studies, this study expounds upon the findings from previous studies to better understand the relationship between medical supply inefficiency due to the influence of stakeholders’ misaligned decision-making in efforts to achieve performance goals. This exploratory, mixed-methods study …

Monotonic Constant Normal Stiffness Tests For Improving The Skin Friction Resistance Prediction Of Drilled Piles In Sand, Amir Babaee

Open Access Dissertations

This body of work consists of three manuscripts. The first manuscript focuses on the evaluation of constant normal stiffness tests on sand using a newly developed active control system. The second manuscript is related to prediction of axial capacity of drilled and grouted micropiles for offshore foundations. The third manuscript corresponds to evaluation of quality control measures for cyclic resistance of sand using cyclic direct simple shear equipment.

Small diameter drilled piles (micropiles) are being considered for use as an economical foundation for floating offshore wind structures. On land, micropiles are typically load tested to confirm design capacity; this is …

Machine Learning For Optimized Ocean Exploration Data Analysis, Puja Banerjee

Open Access Dissertations

The deep sea remains one of the most crucial frontiers in Earth sciences, with vast unknowns regarding its biodiversity, ecosystem dynamics, and geological features and processes, and impact and interaction with humans. Ocean exploration seeks to address this gap by focusing data collection in some of the least known places on the planet in order to significantly expand our knowledge of marine ecosystems, geological formations, and oceanographic processes. Ocean exploration datasets provide crucial insights into a wide range of scientific domains including: deep sea biodiversity, seafloor morphology, and deep-sea soundscapes. The advent of autonomous and remotely operated underwater vehicles (AUVs …

Development And Deployment Of In Situ Fiber Optic Distributed Temperature Sensing Systems And Data Processing Workflows For Oceanographic Observatories In Coastal And Deep-Sea Environments, Johann Sebastian Becker

Open Access Dissertations

Over the last two decades, fiber optic distributed temperature sensing (DTS) has emerged as a transformative technology capable of providing unprecedented spatiotemporal resolution observations of temperature in a broad range of environmental sensing, industrial, and civil engineering monitoring applications. DTS uses a single interrogator unit to measure temperature continuously along an optical fiber, effectively turning the fiber into the equivalent of an array of temperature probes that can be interrogated synoptically. Modern commercially-available DTS systems are capable of continuous sensing with sampling frequencies up 5 sec, spatial resolution of 0.25 m, and temperature precision up to 0.01 °C) observations, on …

The Effect Of Maternal Diet On Developmental Programming: A Cross Species Analysis, Lindsey Eileen Eaton

Open Access Dissertations

Maternal nutrition plays an important role in shaping offspring health through developmental programming, with lasting implications on metabolic function and disease susceptibility. This dissertation explores the molecular and physical consequences of maternal nutrition, particularly its effects on pancreatic development and function in offspring. Chapter one provides a comprehensive review of the literature, detailing the mechanisms of fetal development, epigenetic regulation, and metabolic programming. It highlights the thrifty phenotype hypothesis, the role of DNA methylation and histone modifications, and the impact of maternal nutrition, emphasizing how nutrient availability during pregnancy influences fetal organogenesis and long term metabolic health.

Chapter two examines …

Numerical Modeling Study Of Coastal Impacts From Extreme Storms And Sea Level Rise In Southern New England, Deborah Crowley

Open Access Dissertations

Coastal areas in southern New England are vulnerable to a range of impacts from extreme storms and sea level rise. The most frequent extreme storms are extratropical storms, commonly referred to as nor’easters, named for the direction of the strongest winds, though these storms also have strong winds from other directions.

Storm winds generate large waves and push water up along the coast in the form of storm surge. The combined impacts of increased water levels and waves include flooding and morphological change. Sea level rise (SLR) will exacerbate these processes, amplifying the associated impacts, which may pose increasing threats …

Dynamics Of Metal-Coordinated Coumarin Dyes For Photoswitching Applications, Danielle Jacoby

Open Access Dissertations

Optical transient absorption spectroscopy is a fundamental pump-probe technique that is used to analyze the photophysical and photochemical properties of molecules. Our research group specifically utilizes both a femtosecond and nanosecond set up to probe dynamics of molecules on time scales ranging from 100s of femtoseconds to approximately 50 microseconds. Chapter 2 is a standard operating procedure for the nanosecond transient absorption instrument.

Photoacids are molecules that undergo a change in the acidity of one of their protons when exposed to light. Utilizing this phenomenon, we have designed a series of dyes that, when bound to divalent first row transition …

Electro-Vascular Dynamics During Auditory Processing: Variation Along The Schizotypy Continuum, John P. Mclinden

Open Access Dissertations

Electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) are complementary noninvasive neuroimaging modalities that have contributed greatly to our understanding of the mechanisms of auditory processing. As an emerging technology, fNIRS has produced promising insights into the mechanisms of auditory processing, although considerable work remains to characterize hemodynamic responses in auditory tasks. In addition, the complementary nature of EEG and fNIRS and the relationships between the signals they record have been underexplored. In particular, nonlinear interactions between these signals remain under-characterized, despite the potential benefit to future multimodal neuroimaging studies. A challenge in understanding these interactions is the influence of systemic …

Democratizing Deep-Sea Technology Development Using Rapid Prototyping Techniques, Breanna Motsenbocker

Open Access Dissertations

Deep-sea research and exploration have consistently been inaccessible to a broader oceanographic community due to the lack of affordable technology and resources that are required for this type of work. Traditionally, to investigate the deep sea, large research vessels are required to operate the expensive and massive equipment that can withstand the intense pressure and harsh environment beyond 200 meters of water. Not only does this lessen the capacity for exploring the deep sea but it also introduces an extreme inequity for who can participate and lead these efforts. With a growing demand for the global Blue Economy and a …

Light, Symbiosis, And The Biology Of Corals, Taylor R. Lindsay

Open Access Dissertations

Light is critical for the survival of most shallow water scleractinian corals. Corals are mixotrophs, acquiring energy via both feeding on water column plankton and photosynthesis via a symbiotic relationship with dinoflagellates living within their tissues. Corals rely heavily on photosynthetically derived metabolites through this symbiotic relationship, intrinsically linking their biology to light availability. Corals are known to modulate their biology to maximize light capture. However, there is a limited understanding of the interaction between morphology, physiology, and energetic strategy, as well as how light may affect these relationships. In Chapter 1, we quantified the morphology, physiology and energetic …

Development Of A Scituate Reservoir Mitigation Model For Assessing Flood Control During Extreme Scenarios, Supria Paul

Open Access Dissertations

Effective reservoir management is essential for mitigating downstream flooding, especially with the increasing frequency and intensity of extreme weather events impacting major drinking water reservoirs such as the Scituate Reservoir in Rhode Island. These reservoirs provide water for large populations but can be overwhelmed by intense precipitation, flooding and land cover changes. Climate change is expected to increase precipitation in the study area located in New England, highlighting the need for improved reservoir systems, especially given the aging dams and higher risk of failures. Additionally, land cover changes, like the widespread defoliation caused by the Gypsy Moth infestations, affect water …

Novel Methodology And Proof-Of-Concept For Proton Ct Using Spot Profile Rather Than Bragg Peak Location, Brett Albert Ruben

Open Access Dissertations

Proton radiation therapy offers a highly precise method for cancer treatment, theoretically providing superior dose deposition characteristics compared to conventional X-ray radiation therapy. Its steep and finite dose fall-off region allows for superior tumor coverage while reducing, though not eliminating, dose to surrounding healthy tissue. However, its full potential is limited by range uncertainties, particularly those arising from the reliance on X-ray-based imaging methods called computed tomography (CT) for proton-based treatment. CT image Hounsfield Units (HU) must be converted to stopping power ratios (SPR) as these ratios are the clinically relevant value for accurately planning particle interactions during proton therapy. …

Entrepreneurial Selling And Business Success In Brazil, Renato Fernandes

Open Access Dissertations

This study aimed to deepen the understanding of the relationship between Entrepreneurial Selling and business success in Brazil through two different studies about the antecedents and consequences of Entrepreneurial Selling.

Using grounded theory and an exploratory-confirmatory mixed methods design, this dissertation demonstrates that Entrepreneurial Selling is crucial for business success. The database was sufficiently diverse for an in-depth analysis of the entrepreneurial Brazilian context: 777 entrepreneurs participated in the studies, ranging from first-time founders and serial entrepreneurs, leading B2B, B2C, and B2B2C companies from 31 segments, from startups struggling to make their first million to established companies already earning more …

Intersections Of Inattention: A Qualitative Inquiry Into The Experiences Of Multiply Marginalized Students In Community College Settings, Jana N. Knibb

Open Access Dissertations

Educational research has examined the impact of expanded access to higher education for historically marginalized groups. However, research on the experiences of students who are both racially minoritized and dis/abled is limited. Findings suggest that, due to their intersectional identities, multiply marginalized dis/abled students (MMDS) navigate policies and practices related to racist ableism, which further marginalize them and create additional barriers in their higher education experiences. Expanding this research requires theoretical frameworks that account for students' identities, experiences, and barriers in higher educational spaces and contexts. This qualitative study, grounded in Dis/ability Studies and Critical Race Theory in Education (DisCrit), …

Confronting The Seaport Resilience Gap: Incentives, Frameworks, And Case Studies For Enhancing Resilience To Natural Hazards In Port Planning And Policy, Rosemarie Fusco

Open Access Dissertations

This dissertation investigates the critical issue of seaport resilience, focusing on the gaps in resilience planning and the role of incentives in motivating resilience investment. The research arc addresses the question: What incentivizes seaports to increase natural hazard resilience (NHR)? It is organized into three interconnected manuscripts, each examining distinct aspects of the problem.

The first manuscript critically examines the resilience planning approaches of Small Island Developing States (SIDS) as outlined in their National Adaptation Plans (NAPs), highlighting the limited consideration of seaports despite their critical role in economic and social connectivity. SIDS offer critical insight into seaport resilience due …

Textual Sediments: Genre And The Planetary Novel, William Bowden

Open Access Dissertations

This dissertation investigates how twenty-first-century prose fiction navigates the ecological and temporal dimensions of planetary crisis. In response to accelerating pressures - climate change, ecological collapse, and the intensification of capitalist modernity - literary studies has turned increasingly to the planetary as a conceptual frame. Yet this shift has often outpaced the development of adequate critical vocabularies and narrative methodologies. By drawing on ecocriticism, narrative theory, phenomenology, and related fields, Textual Sediments proposes a new framework for reading what it terms the planetary novel: a sedimentary genre characterized by temporal layering, formal hybridity, and a recursive engagement with scale. Through …

Per- And Polyfluoroalkyl Substances (Pfas) Effects On Tissue Disposition, Proteome, And Health Effects, Juliana Agudelo Areiza

Open Access Dissertations

Per- and polyfluoroalkyl substances are a class of nonbiodegradable synthetic aliphatic environmental toxicants that are ubiquitous in the environment. A small subset, specifically perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA), have been designated as highly hazardous to human health by the Environmental Protection Agency (EPA) under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). PFOA and PFOS-associated adverse health effects include, but are not limited to, immune suppression, thyroid dysfunction, increased serum cholesterol, liver damage (i.e., alanine aminotransferase (ALT)), and developmental toxicity (i.e., low fetal birth weight and neurotoxicity). In this doctoral dissertation, it was hypothesized that environmental PFAS …