Digital Commons Network^™

Detection Of Beef Mince Adulteration Based On Sparse Hyperspectral Feature Selection Algorithm, Ma Yongbo, Peng Yu, Xu Yiping, Li Dan

Food and Machinery

［Objective］ To achieve high -precision detection of beef mince adulterated with pea protein,duck mince,chicken mince,and pork mince by combining hyperspectral technology with sparse hyperspectral feature selection.［Methods］ The original spectral data of the beef mince samples is extracted and processed using standard normal variable transformation (SNV ),multiplicative scatter correction (MSC ),first -order differential (D1),and moving average (MA) preprocessing methods.A hyperspectral feature selection algorithm is designed based on sparse representation.This algorithm constructs a sparse dimensionality reduction framework and uses swarm intelligence optimization to optimize and solve the objective function of spectral feature selection.The spectral data dimensionality is reduced as much as possible …

Online Detection Of Citrus Sugar Content Based On Visible Near-Infrared Reflectance Spectroscopy, Li Liqiao, Gao Zongyu, Shi Ruyi, Nie Jing, Chai Jianmin, Liu Wei

Food and Machinery

［Objective］ To lower the complexity,improve the accuracy and reduce the damage of the detection process of citrus sugar content.［Methods］ An online detection device for citrus sugar content is designed based on visible near -infrared reflectance spectroscopy.With Jinniu Citrus as the research object,the modeling set and verification set are divided by sample set partitioning based on the joint x-y distance (SPXY ) classification method.The partial least square regression (PLS) modeling and detection effects after pretreatment are respectively compared and analyzed by methods including multiple scattering correction (MSC ),standard normal variation (SNV ),and SG -smoothing (SG) to determine the optimal pretreatment method.At …

Non-Destructive Detection Of Kiwifruit Internal Quality Based On Improved Deep Convolutional Neural Network And Spectral Technology, Chen Wei, Fei Wenyuan, Li Chao, Wei Chenxi

Food and Machinery

［Objective］ Dry matter and sugar content are two important indicators affecting the quality of kiwifruit.To achieve rapid and accurate detection of these indicators,a non -destructive detection method for key internal quality indicators of kiwifruit is proposed,integrating improved deep convolutional neural network with spectral technology.［Methods］ A spectrometer was used to collect spectral data of kiwifruit,and the data were transformed into two types of two -dimensional images using Gramian Angular Field (GAF ) transformation.An improved convolutional neural network model with multi -dilated convolutions was constructed to predict and analyze key quality indicators of kiwifruit.The model consists of two independent CNN modules connected …

Overcoming Barriers To Literacy For Individuals Who Need Or Use Aac: Lived Experiences, Key Research Findings, And Future Directions, Janice Light, Christine Holyfield, David Mcnaughton, Dana Nieder, Jamie Preece

Communication Disorders and Occupational Therapy Faculty Publications and Presentations

Literacy supports participation in education, employment, healthcare, and community living, and enhances communication for individuals who need or use augmentative and alternative communication (AAC). Research has demonstrated that individuals with developmental disabilities who need or use AAC can successfully acquire a wide range of literacy skills when provided with effective tools and evidence-based, adapted instruction delivered by trained professionals. Unfortunately, individuals who need or use AAC typically face significant barriers to literacy learning: (1) They may be excluded from literacy instruction or only have access to instruction that requires spoken responses severely limiting their participation; (2) Their service providers may …

Our Ethical Duty: Assessing The Competencies Of Counselors-In-Training For Counseling With Transgender And Gender Expansive Clients, Deanna N. Cor, M. N. Saltis, Megan Doughty Shaine, Lauren Streeter

Counselor Education Faculty Publications and Presentations

Counselors report a lack of competence in working with transgender and gender expansive (TGE) individuals. TGE people report a lack of competent and affirming care. This study used the Gender Identity Counselor Competency Scale- Revised (GICCS-R) to understand self-reported competence and training levels in working with this population. Participants were 90 masters-level counselors in training who had at least started practicum in CACREP-accredited programs. Hierarchical linear regression was utilized to determine factors that predict competence including identities and training levels. Results highlight a lack of perceived competence in skill-based training. Counselor education programs must focus on improving TGE affirmative skills.

Testosterone Deficiency And Treatments: Common Misconceptions And Practical Guidance For Patient Care, Mohit Khera, James M Hotaling, Martin Miner

Faculty, Staff and Students Publications

Introduction: Misconceptions about testosterone therapy are prevalent and there is an unmet need for a review of current literature that can be leveraged by physicians to deliver safe and effective care for men with hypogonadism.

Objectives: This review aims to address common misconceptions about testosterone therapy using current literature and synthesize practical guidance for clinicians with patients who are starting testosterone therapy.

Methods: A literature search of PubMed, Embase, CINAHL was carried out to identify associations between testosterone therapy and prostate cancer, cardiovascular risk, and hepatic toxicity; definitions of hypogonadism; and practical guidance for clinician with patients starting testosterone therapy. …

The Trapping Of Live Neutrophils By Macrophages During Infection, Kelley N Cooper, Marina Terekhova, Barbara Potempa, Ana D'Aubeterre, Jerome Timbol, Si An Chen, Antoine Dufour, Shunying Jin, Maxim N Artyomov, Jan Potempa, Juhi Bagaitkar

2020-Current year OA Pubs

Neutrophils are highly abundant in the oral mucosal tissues, and their balanced activation and clearance are essential for immune homeostasis. Here, we demonstrate that neutrophils infected with the bacterial pathogen Porphyromonas gingivalis (Pg) are captured alive by macrophages in a manner that bypasses all known receptor-ligand interactions involved in the phagocytosis of either live or dead cells. Mechanistically, upon interaction with Pg, or its protease RgpB (gingipains), live neutrophils undergo rapid remodeling of their proteomes, generating neoepitopes. N-terminomics-based proteomic profiling identified multiple RgpB cleavage sites on several azurophilic granule proteins that are translocated to the surface of live neutrophils via …

Service Learning As A Mode To Deliver Course Learning Outcomes In A Research-Based Exercise Science College Course, Jennifer Lape Kaiser, Madison Skaggs

Journal of Community Engagement and Higher Education

The following case study presents an approach to teaching research courses in undergraduate exercise science programs. Research courses are commonly required in the curriculum for this degree. Service learning (SL) is an effective way to promote student learning outcomes (SLOs) by providing hands-on experience for the students, and should be considered in exercise science research courses. Quantitative and qualitative survey results from students over two semesters of SL in an exercise science course are presented.

Exploring The Impact Of A Middle Level School Therapy Dog On Students And Staff And Connections To Best Practices In Middle School Education, Brandye Nobiling, Sherry Maykrantz, Tara Downes, Joshua Nobiling

Current Issues in Middle Level Education

The presence of therapy dogs in schools has increased due to the growing body of research showing positive effects of assisted-animal interaction. But there is little published research on how an innovation such as a therapy dog connects to best practices in middle level education. The goal of the research was to use the Diffusion of Innovation (DOI) theory to connect the implementation of a therapy dog to the Association for Middle Level Education’s (AMLE) essential attributes and characteristics as well as components of the Centers for Disease Control and Prevention’s Whole School, Whole Community, Whole Child (WSCC) model. Focus …

Exploring The Impact Of A Literacy-Based Service-Learning Project On Pre-Service Teachers, Shelly J. Landreth, Tara Wilson

Journal of Community Engagement and Higher Education

In this study, we describe a teacher educator’s first experience implementing a service-learning project in a children’s literature course in which pre-service teachers helped provide read-alouds for the local public library’s summer reading program. We sought to examine the impact the project had on the seven participants. Data was collected through reflective journals and an end-of-course debrief. Four themes were identified in the data: Initial Feelings, Preparation and Planning, Lessons Learned, and Barriers and Challenges.

Gastroplus® As Simulating/ Conducting Software For Modeling Physiologically-Based Pharmacokinetics & Physiologically Based Biopharmaceutics., Yasir Qasim Almajidi, Rafif Raad Faisal, Ahmed Yaseen, Maher Abdulrazzaq Luqman Al-Hakeem

Maaen Journal for Medical Sciences

The development of dosage forms necessitates the evaluation of pharmacokinetics and pharmacodynamics (PK/PD), which aids scientists in elucidating the drug's mechanism of action and achieving optimal composite design. The incorporation of pharmacokinetic/pharmacodynamic (PK/PD) efficacy studies in the early phases of lead identification and optimisation within drug development can markedly expedite the selection of the most promising dosage forms. The rapid advancement of computer hardware, software, and algorithms, along with drug screening and PK/PD evaluation, has significantly benefited from various computational methods, which substantially decrease the time and cost associated with drug development. Computational pharmacokinetic/pharmacodynamic modelling enhances the translation of in …

Co-Optive Constitutionalism, Raquel Muñiz, Andrés Castro Samayoa

Northwestern Journal of Law & Social Policy

In this Article, we introduce the concept of co-optive constitutionalism, a rhetorical mechanism through which the U.S. Supreme Court dismantles civil rights protections while paradoxically employing civil rights language to legitimize these regressive outcomes. Through a detailed analysis of the majority, concurrences, and dissents in Students for Fair Admissions v. Harvard, we demonstrate how the Court's conservative majority strategically appropriates progressive ideals, selectively quotes precedent, and redefines equality to justify overturning decades-long precedent permitting race-conscious admissions. We situate co-optive constitutionalism within the broader conservative legal political movement spearheaded by the Federalist Society, revealing how judicial rhetoric aligns with conservative political …

The Walk Away From Racial Equality, Areto Imoukhuede

Northwestern Journal of Law & Social Policy

This article demonstrates that the U.S. Supreme Court has walked away from racial equality in favor of the same liberal equality approach that was the foundation for Plessy v. Ferguson’s “separate but equal” doctrine. The Court’s recent affirmative action cases, from Grutter and Gratz v. Bollinger, to Fisher v. University of Texas, to Students for Fair Admissions v. President and Fellows of Harvard College, all apply a liberal equality theory that is hostile to racial equality. In the lead-up to these cases, the Court abandoned its Brown-era interpretation of equality under the Fourteenth Amendment Equal Protection Clause in favor of …

Individual Noise-Tolerance Profiles And Neural Signal-To-Noise Ratio: Insights Into Predicting Speech-In-Noise Performance And Noise-Reduction Outcomes, Subong Kim, Susan Arzac, Natalie Dokic, Jenn Donnelly, Nicole Genser, Kristen Nortwich, Alexis Rooney

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Background/Objectives: Individuals with similar hearing sensitivity exhibit varying levels of tolerance to background noise, a trait tied to unique individual characteristics that affect their responsiveness to noise reduction (NR) processing in hearing aids. The present study aimed to capture such individual characteristics by employing electrophysiological measures and subjective noise-tolerance profiles, and both were analyzed in relation to speech-in-noise performance and NR outcomes. Methods: From a sample of 42 participants with normal hearing, the neural signal-to-noise ratio (SNR)—a cortical index comparing the amplitude ratio between auditory evoked responses to target speech onset versus noise onset—was calculated, and individual noise-tolerance profiles were …

Community-Based, Culturally Relevant Stem: Engaging Rural And Indigenous Students Through Partnerships, Institutional Flexibility, And One Health, Ellen Chenoweth, Paul Cotter, Janice Straley, Kari Lanphier

Faculty, Staff, and Students

Rural and Indigenous students face many barriers to persistence in biomedical and STEM trajectories including poor access to science experiences, a dearth of relatable educational resources, and educational structures misaligned with rural and Indigenous student and community needs. Rural Alaska Students in One Health Research (RASOR) is designed to provide a positive first college experience for rural and Indigenous students. Key innovations include 1) a partnership between the University of Alaska and tribal governments to allow for culturally relevant, locallymentored research experiences and 2) a customizable program structure. We also surveyed adults in the region regarding attitudes about science, its …

Current Landscape Of Preclinical Models For Pediatric Gliomas: Clinical Implications And Future Directions., Syed M. Faisal, Monika Yadav, Garrett R. Gibson, Adora T. Klinestiver, Ryan M. Sorenson, Evan Cantor, Maria Ghishan, John R. Prensner, Andrea T. Franson, Kevin Ginn, Carl Koschmann, Viveka Nand Yadav

Manuscripts, Articles, Book Chapters and Other Papers

Pediatric high-grade gliomas (pHGGs), particularly diffuse midline gliomas (DMGs), are among the most lethal brain tumors due to poor survival and resistance to therapies. DMGs possess a distinct genetic profile, primarily driven by hallmark mutations such as H3K27M, ACVR1, and PDGFRA mutations/amplifications and TP53 inactivation, all of which contribute to tumor biology and therapeutic resistance. Developing physiologically relevant preclinical models that replicate both tumor biology and the tumor microenvironment (TME) is critical for advancing effective treatments. This review highlights recent progress in in vitro, ex vivo, and in vivo models, including patient-derived brain organoids, genetically engineered mouse models (GEMMs), and …

Transcendental Arguments In Reid? A Reply To Mccraw, Peter Baumann

Philosophy Faculty Works

Benjamin W. McCraw’s article “A Reidian Transcendental Argument Against Skepticism” (2025) constitutes an original and thought-provoking contribution both to Reid scholarship and to the discussion of epistemic skepticism.[1] In the following I will make a few remarks about it, focusing on the discussion of skepticism. I start with a brief historical remark on Reid and Kant (§ 1) before I explain the anti-skeptical argument in some detail (§ 2). A discussion of the premises of the argument follows (§ 3). I add some remarks about the social aspect of McCraw’s anti-skeptical stance (§ 4). I finish with another set of …

The Theoretical Role Of The Wind In Aerosolising Microplastics And Nanoplastics From Coastal Combined Sewer Overflows, Lauren Biermann, David Moffat, Clive E Sabel, Thomas E Stovin

School of Geography, Earth and Environmental Sciences

Inhaled microplastics and nanoplastics (MNPs) have shown bio-persistence in the body, with concerning implications for human health. Airborne MNPs primarily originate from terrestrial sources, but sea air may contribute when onshore 'aerosolising' winds coincide with high concentrations of MNPs in surface waters. From the thousands of cities worldwide with Combined Sewer Overflows, millions to billions of MNPs can be discharged daily into rivers, estuaries, and the sea. To assess the possible links between water pollution and air quality, we analysed two years of Combined Sewer Overflows (spills) off Plymouth, UK, alongside same-day and long-term meteorological and satellite data. Winds exceeding …

Detecting Ionospheric Disturbances Using High Frequency Coastal Radar Transmissions From The West Coast Of The United States, Riley N. Troyer, Kenneth Obenberger, Michael Negale, Eugene Dao, Zsolt Balint, Eric Burnside, Kris Robinson, Jeffrey M. Holmes, Pavel Inchin, Jonathan Snively

Space Dynamics Laboratory Publications

Coastal radar system are located around the world and many happen to transmit at frequencies capable of skywave propagation via the ionosphere. Therefore, they can be detected hundreds to thousands of kilometers away. This paper demonstrates the opportunity to detect 39 Coastal Ocean Dynamics Application Radar transmitters located on the western coast of the United States using three HF radio receivers in Utah and New Mexico. It also illustrates the possibility to use the phase and Doppler measurements of these signals to derive displacements of the refracting ionospheric layer up to meter resolution for the 2023 annular solar eclipse, an …

Staff Education Project An Educational Project To Educating Mental Health Staffs On Stress Management To Improve Knowledge And Staff Retention, Lilian Eneude

Walden Dissertations and Doctoral Studies

This evidence-based educational project addressed the knowledge gap in stress management techniques among mental health nursing staff at an acute psychiatric facility. Mental health professionals experience substantially higher rates of workplace stress and burnout compared to other healthcare workers, affecting staff wellbeing, patient care quality, and organizational outcomes. The practice-focused question was: Does educating mental health nurses on stress management improve knowledge as evidenced by pre- and post-intervention? A comprehensive literature search was done at the Walden University Library using CINAHL, PubMed, and PsycINFO databases that yielded 200 potential articles, with 45 full-text articles reviewed and 20 high-quality studies included …

Lived Experiences Of Ex-Offenders In Securing Stable Employment After Reentry Programs, Tony Lemar Williams

Walden Dissertations and Doctoral Studies

The reintegration of formerly incarcerated individuals into society has garnered increasing attention largely due to structural and social barriers that impede their successful transition. The purpose of this qualitative descriptive phenomenological study was to explore the lived experiences of ex-offenders who successfully obtained gainful employment following their reintegration into society while navigating the enduring consequences of their past convictions. Self-determination, self-efficacy, and implicit theories grounded this study. Ten participants were recruited through social media platforms and flyers on community billboards in a suburban area of Ohio. Data were collected using semistructured in-depth interviews. Narrative coding, according to Saldana, was used …

Strategies In Cybersecurity For The Protection Of Patient Health Information (Phi), Denise Holloway

Walden Dissertations and Doctoral Studies

Health information technology (IT) professionals are consistently seeking better ways to balance the availability of patient health information (PHI) with data breach prevention, as these breaches negatively impact health organizations legally and ethically due to the exposure of PHI. However, some health IT professionals lack strategies to protect PHI against cybersecurity attacks. Grounded in Dr. Edward Hutchins’ distributed cognition framework, the purpose of this qualitative pragmatic inquiry was to understand what strategies health IT professionals use to protect PHI against cybersecurity attacks. The participants were six IT professionals from Washington D.C., Maryland, and Virginia with at least five to seven …

Elementary School Administrators Perceptions Of School-Wide Restorative Practices In A School District In Georgia, Simone Simmons

Walden Dissertations and Doctoral Studies

This basic qualitative study explored the perceptions of elementary school administrators regarding the uses of restorative practices (RPs) to address an increase in undesirable behaviors among K–5 students in a northern public school district in Georgia. Guided by restorative justice theory, which emphasizes repairing harm and fostering positive relationships, the study focused on understanding how administrators perceive the effectiveness of RPs in managing student behavior during instructional time. The research questions focused on administrators’ perceptions of the effectiveness of RPs in addressing student behaviors in the classroom. Data were collected through semi-structured interviews with 10 elementary school administrators from the …

Cat: A Conditional Association Test For Microbiome Data Using A Permutation Approach, Yushu Shi, Liangliang Zhang, Kim-Anh Do, Robert R Jenq, Christine B Peterson

Faculty, Staff and Student Publications

In microbiome analysis, researchers often seek to identify taxonomic features associated with an outcome of interest. However, microbiome features are intercorrelated and linked by phylogenetic relationships, making it challenging to assess the association between an individual feature and an outcome. This paper proposes a novel conditional association test, CAT, that can account for other features and phylogenetic relatedness when testing the association between a feature and an outcome. CAT adopts a permutation approach, measuring the importance of a feature in predicting the outcome by permuting operational taxonomic unit/amplicon sequence variant counts belonging to that feature from the data and quantifying …

Pol Θ-Mediated End-Joining Uses Microhomologies Containing Mismatches, Yuzhen Li, Ngoc K Dang, Wei He, Mark Returan, Denisse Carvajal-Maldonado, Adele T Guerin, Han Xu, Bin Liu, Richard D Wood

Faculty, Staff and Student Publications

DNA polymerase theta (Pol θ) initiates repair of DNA double-strand breaks by pairing single strands at short "microhomologies". It is important to understand microhomology selection, as some cancer cells rely on Pol θ for survival. Here, we investigate end-joining by purified human Pol θ, employing DNA sequencing of products generated from oligonucleotide libraries having diverse 3' ends. Pol θ overwhelmingly selects short internal microhomologies found within 15 nucleotides of the terminus of single-stranded DNAs, restricting deletion size during end-joining. Significantly, we find that the selected microhomologies are usually interrupted by mismatches and that base pairing within 6 nucleotides of the …

A Hedgehog-Foxf Axis Coordinates Dental Follicle-Derived Alveolar Bone Formation, Mizuki Nagata, Gaurav T Gadhvi, Taishi Komori, Yuki Arai, Chiaki Tsutsumi-Arai, Angel Ka Yan Chu, Seth N Nye, Yuntao Yang, Shion Orikasa, Akira Takahashi, Peter Carlsson, W Jim Zheng, Joshua D Welch, Noriaki Ono, Wanida Ono

Faculty, Staff and Student Publications

The alveolar bone is a specialized mineralized structure supporting the lifelong functionality of the tooth in mastication. The alveolar bone develops from the dental follicle (DF) during tooth root formation due to deliberate epithelial-mesenchymal interactions. However, how DF progenitor cell fates are regulated toward alveolar bone osteoblasts remains unknown. We find that Hedgehog signaling activities are transiently activated during the onset of tooth root formation and alveolar bone formation. Parathyroid hormone-related protein (PTHrP)-expressing DF cells are highly responsive to Hedgehog signaling, yet constitutive Hedgehog activation using Pthrp-creER and Ptch1-floxed alleles potently suppresses alveolar osteoblast and ligament differentiation of PTHrP+ DF …

Discharge System Field Sampling Plan, 2025 Update Silver Bow Creek/Butte Area Npl Site Butte Mine Flooding Operable Unit | Butte, Montana, Mark Thompson, Dave Griffis

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Structural And Functional Characterization Of Creb-Binding Protein (Crebbp) As A Histone Propionyltransferase, Guiling Cui, Marie Ley, Ariel E Mechaly, Linh-Chi Bui, Christina Michail, Jérémy Berthelet, Julien Dairou, Haopeng Yang, Guillaume Chevreux, Gautier Moroy, Michael R Green, Ahmed Haouz, Fernando Rodrigues Lima

Faculty, Staff and Student Publications

In addition to histone acetylation, histone lysine propionylation (such as the H3K18Pr mark) has recently attracted significant attention as a common and abundant modification linking the cellular metabolic state and gene expression. CREB-binding protein (CREBBP) and EP300 are key histone acetyltransferases that play a critical role in gene expression through their catalytic activity. Although CREBBP and EP300 are homologous enzymes with high structural similarities, they exhibit both redundant and specific functions. Dissecting the shared and divergent properties of CREBBP and EP300 is thus important to understand their roles. However, despite the importance of CREBBP, most mechanistic and structural studies have …

Vân Lê, Vân Lê '26, Nathalie Romero '25, Posse Legacy Project, Illinois Wesleyan University

All oral histories

Interview of Vân Lê on July 2, 2025 Vân Le is a Posse 6 Scholar who double majored in Political Science and International Global Studies Vân was also a member of the Multilingual Accessibility RSO, Pi Sigma Alpha and Scholars at Risk chapter at IWU. She was also an Eckley Scholar for 2025.

Differential Efficacy Of Bevacizumab And Erlotinib In Preclinical Models Of Renal Medullary Carcinoma And Fumarate Hydratase-Deficient Renal Cell Carcinoma, Niki M Zacharias, Manuel Ozambela, Menuka Karki, Rong He, Pankaj K Chauhan, Pedro I Pesquera, Andres E Hernandez Gonzalez, Oscar Ochoa, Alberto Pieretti, Huiqin Chen, Carolyn De La Cerda, Zhiyuan Yu, Abha Grover, Samantha Hicks-Peña, Natalie W Fowlkes, Lei Wang, Tapati Maity, Priya Rao, Giannicola Genovese, Nizar M Tannir, Jose A Karam, Pavlos Msaouel

Faculty, Staff and Student Publications

Renal medullary carcinoma (RMC) and fumarate hydratase (FH)-deficient renal cell carcinoma (RCC) are rare and highly aggressive cancers. Although the combination of vascular endothelial growth factor (VEGF) inhibition by bevacizumab and epidermal growth factor receptor (EGFR) inhibition by erlotinib is clinically used for both diseases, the differential effect of each component has not been investigated. Transcriptomic profiling revealed that RMC and FH-deficient tumor tissues demonstrate increased EGFR but not VEGF expression compared with adjacent normal kidney. Subsequent in vitro studies revealed that RMC and FH-deficient cell lines are sensitive to erlotinib treatment, whereas clear cell RCC cell lines are resistant. …