Digital Commons Network^™

Positive And Negative Parity States Of 226-236th Isotopes, Ali A. Mezban, Falih H. Al-Khudair

Karbala International Journal of Modern Science

The level scheme of the ^226-236Th nuclei is analyzed using the Interacting Boson Model (IBM-1). The ground state band (g. s.-band), beta band (β-band), gamma band (γ-band) have been described in the sd model space. To calculate the negative parity energy levels, the model space is extended to sdf by adding the f-boson (L=3). A sequence of states in energy bands up to 3.5 MeV has been obtained. The decay of negative states below 1 MeV built on an octupole vibration modes is investigated. The transition probabilities in-band and inter-band are calculated using the wave function of the …

Systems And Methods For Training Frameworks To Optimize Model Based On Business Goals, Chinamy Narendra Sonar, Shuhan Zhang, Keyi Li, Lin Meng, Can Liu, Shubham Agrawal, Chiranjeet Chetia

Defensive Publications Series

[0001] The present disclosure provides a system and method for providing training frameworks to optimize model based on business goals. The processor of the training framework system introduces novel model evaluation metrics which are directly aligned with business goals and capture most business use cases for A2A fraud detection models. Metrics can be used in model training and evaluation. In the first approach, the processor of the training framework system sets validation criteria to a new metric but training the model with traditional loss. In the second approach, the processor of the training framework system trains and validates the model …

Institutional Animal Care And Use Committees And The Challenges Of Evaluating Animal Research Proposals, John J. Pippin, Jarrod Bailey, Mark Kennedy, Debra Dubow Press, Janine Mccarthy, Ron Baron, Stephen Farghali, Elizabeth Baker, Neal D. Barnard

Non-Animal Methods and 3Rs

In the U.S. and many other countries, oversight committee approval is a common requirement for conducting research and publishing its findings. However, in evaluating whether research aims could have been achieved by methods other than the use of animals, these committees face a challenging task. In the U.S., there is no requirement that committee members have expertise in the research areas under review or in methods that could replace animal use, nor could expertise in such vast technical areas be expected. Consideration of alternatives to painful procedures is not required at all for experiments on animals not covered by the …

Experiences Of Managing And Living With Autoimmune Addison’S Disease In The Younger And Newly Diagnosed Adults: An Interpretative Phenomenological Analysis, Mathew Horodner

Walden Dissertations and Doctoral Studies

There is a lack of knowledge regarding the experiences of managing and living with autoimmune Addison’s disease (AD) in the younger and newly diagnosed adults. AD research usually focuses on biological or medication studies. Thus, the purpose of this qualitative study was to understand the lived experiences of the younger and newly diagnosed adults living with autoimmune AD. Consisting of the complex integration of biological, psychological, and social factors, Engel’s biopsychosocial model served as the study’s conceptual framework. I conducted this study to include the experiences of managing and living with autoimmune AD in the younger (18–35) and newly diagnosed …

Development And Characterization Of Pmma/Pvp Nanofiber-Loaded Bioactive Agents With Enhanced Breast Cancer Activity, Samar A. Salim, The British University In Egypt, Esraa Abdelazim, Marwa Abdel Aleem

Nanotechnology Research Centre

Breast cancer remains a leading cause of cancer-related mortality globally, driving the need for novel effective and less toxic therapeutic agents. This study explores the synthesis and characterization of bioactive compounds: 1-(4-methoxyphenyl)-N- (p-tolyl)methanimine (MPTI), N-(4-methylphenyl)benzamide (MPB), and 4-methyl-N-(p-tolyl)benzenesulfonamide (MTS), and their incorporation into a PMMA/PVP polymer matrix for potential anticancer applications. Morphological analysis of the PMMA/PVP-loaded agents via SEM depicts structural modifications in the PMMA/PVP nanofibrous matrix upon incorporation of the bioactive agents. The FTIR analysis of the synthesized compounds before and after loading into the 7PMMA:3PVP nanofibers reveals successful incorporation of MPTI, MPB, and MTS, with characteristic absorption bands …

Neural Associations Between Fingerspelling, Print, And Signs: An Erp Priming Study With Deaf Readers, Brittany Lee, Sofia E. Ortega, Priscilla M. Martinez, Katherine J. Midgley, Phillip J. Holcomb, Karen Emmorey

Communication Sciences and Disorders Faculty Articles and Research

Fingerspelling is a leading predictor of reading ability for deaf people who use a signed language, but few neuroimaging studies have examined how it supports reading. We used event-related potentials to investigate how fingerspelled words prime printed words. Twenty-four skilled deaf adult readers completed a Go/No-Go task while viewing printed English word targets following related and unrelated primes in one of three conditions: printed English words, American Sign Language (ASL) signs, and fingerspelled words. N400 priming effects were strong across all three conditions. Early N400 effects were similar for printed word primes and fingerspelled word primes, suggesting shared orthographic representations. …

Communication Enhancement Strategies To Mitigate Functional Siloes In Head Start Programs, Maryom G. Mccloud

Walden Dissertations and Doctoral Studies

Inefficient internal communication between program and financial operations may negatively affect organizational performance and profitability. Some Head Start Program (HSP) leaders are concerned with communication failures because of the potential to negatively impact business productivity and profitability. Grounded in business process re-engineering, the purpose of this qualitative single case study was to explore strategies used by HSP leaders to increase communications between program and financial operations to increase profitability. The participants were four HSP leaders located in the Northern Region of the United States, who successfully implemented such strategies. Data were collected from semistructured interviews and company documents. Through thematic …

Mesenchymal Stem Cell-Derived Extracellular Vesicles: Seeking Into Cell-Free Therapies For Bone-Affected Lysosomal Storage Disorders, Andrés Felipe Leal, Harry Pachajoa, Shunji Tomatsu

Department of Pediatrics Faculty Papers

Lysosomal storage disorders (LSDs) constitute a group of monogenic systemic diseases resulting from deficiencies in specific lysosomal enzymes that cause the intralysosomal accumulation of non- or partially degraded substrates, leading to lysosomal dysfunction. In some cases of LSDs, the bone is more severely affected, thus producing skeletal manifestations in patients. Current therapies, such as enzyme replacement therapy (ERT) and gene therapy (GT), show limited efficacy in correcting skeletal abnormalities. Increasing evidence suggests that microenvironmental disturbances also contribute significantly to disease pathogenesis. Therefore, therapeutic strategies targeting lysosomal dysfunction and microenvironmental dysregulation are needed. Mesenchymal stem-cell-derived extracellular vesicles (MSC-EVs) are emerging as …

Reduction-Driven Mobilization Of Structural Fe In Clay Minerals With High Fe Content, Anke Neumann, Luiza Notini, W. A.P.Jeewantha Premaratne, Drew E. Latta, Michelle M. Scherer

Michigan Tech Publications

Clay minerals contain significant amounts of Fe in their alumosilicate framework, and this structural Fe can be reduced and re-oxidized, constituting a potentially renewable source of reduction equivalents in sedimentary environments. However, dissolution and/or clay mineral transformations during microbial Fe reduction contradict this concept. Here, we investigate how Fe reduction and re-oxidation affect the propensity of Fe to be released from the clay mineral structure and use selective sequential extractions in combination with Mössbauer spectroscopy. Negligible amounts of Fe were released in the sequential extraction of high Fe content clay minerals NAu-1 and NAu-2. Once aqueous Fe(II) was added as …

Pharmacological Considerations For Healthcare Providers When Caring For Muslim Patients: A Practical Guide, Layla Abubshait, Nissa Tasnim, Taha Cangoz

Einstein Health Papers

Healthcare providers increasingly encounter Muslim patients with unique pharmacological considerations influenced by religious beliefs and practices. Islam, as the world's second-largest religion, includes specific guidelines affecting medication permissibility, particularly regarding alcohol and pork-derived ingredients. This educational guide examines the intersection of Islamic teachings with pharmacotherapy, providing examples of commonly prescribed medications containing alcohol or porcine-derived gelatin from our academic medical center's inpatient and outpatient formulary. We document alcohol content percentages in various medications and suggest possible alternatives as illustrative examples. Most importantly, we present a step-by-step practical framework for using National Drug Code (NDC) numbers and the DailyMed database, enabling …

Staff Education Project: Staff Education To Improve Nurses’ Knowledge, Self-Efficacy, And Motivation In Supporting Medication Adherence, Giovanna Happy

Walden Dissertations and Doctoral Studies

Medication nonadherence among individuals with psychiatric disorders remains a significant barrier to recovery, ranging from 40% to 60%. Contributing factors include fear of side effects, stigma, cognitive limitations, and complex regimens. This staff education project addressed challenges through the implementation of a structured, evidence-based intervention to improve adherence-supportive practices among 14 outpatient psychiatric nurses. A preimplementation needs assessment revealed inconsistent application of adherence strategies and low staff confidence. The project’s objective was to evaluate whether a structured education program could improve nurses’ knowledge by 15%, confidence by 15%, and willingness by 3.5 points on a Likert scale to promote medication …

Staff Education On Colorectal Cancer Screening To Improve Knowledge And Usage, Mary Tessie Thullah Bangura

Walden Dissertations and Doctoral Studies

Executive Summary: Staff Education Project Staff Education on Colorectal Cancer Screening to Improve Knowledge and Usage

Pan-Cancer Immune And Stromal Deconvolution Predicts Clinical Outcomes And Mutation Profiles, Bhavneet Bhinder, Verena Friedl, Sunantha Sethuraman, Davide Risso, Kami E Chiotti, R Jay Mashl, Kyle P Ellrott, Jordan A Lee, Christopher K Wong, Kofi Gyan, Aditya Deshpande, Marcin Imielinski, Rohan Bareja, Josh Stuart, Myron Peto, Katherine A Hoadley, Alexander J Lazar, Andrew D Cherniack, Jingchun Zhu, Shaolong Cao, Mark Rubin, Wenyi Wang, Oliver F Bathe, Nicolas Robine, Li Ding, Peter W Laird, Wanding Zhou, Hui Shen, Vésteinn Thorsson, Jen Jen Yeh, Matthew H Bailey, Daniel Cui Zhou, Xianlu L Peng, Mary Goldman, Yongsheng Li, Anil Korkut, Nidhi Sahni, D Neil Hayes, Michael K A Mensah, Ina Felau, Anab Kemal, Samantha Caesar-Johnson, John A Demchok, Liming Yang, Martin L Ferguson, Roy Tarnuzzer, Zhining Wang, Jean C Zenklusen, Paul Spellman, Olivier Elemento

Faculty, Staff and Student Publications

Traditional gene expression deconvolution methods assess a limited number of cell types, therefore do not capture the full complexity of the tumor microenvironment (TME). Here, we integrate nine deconvolution tools to assess 79 TME cell types in 10,592 tumors across 33 different cancer types, creating the most comprehensive analysis of the TME. In total, we found 41 patterns of immune infiltration and stroma profiles, identifying heterogeneous yet unique TME portraits for each cancer and several new findings. Our findings indicate that leukocytes play a major role in distinguishing various tumor types, and that a shared immune-rich TME cluster predicts better …

Chromatography In Analysis And Quality Control Of Oil And Gas Products: Modern Approaches And Prospects, Muborak Akramovna Mirshomilova, Natalia Evgenievna Sheina, Lala Bekirova

Technical science and innovation

Chromatography plays a key role in the analysis and quality control of oil and gas products. Modern chromatographic methods, including gas and liquid chromatography, provide high accuracy, sensitivity and speed of analysis. They allow you to identify impurities, control the composition and compliance of products with standards. The article considers innovative approaches, such as multidimensional chromatography and the use of automated systems. Development prospects are discussed, including integration with AI and digital technologies, which opens up new opportunities to improve the efficiency of quality control in the oil and gas industry. This article considers the role of chromatographic methods in …

Supporting Patients With Advanced Cancer And Their Spouses In Parenting Minor Children: Results Of A Randomized Controlled Trial, Kathrin Milbury, Sujin Ann-Yi, Meagan S Whisenant, Morgan Jones, Yisheng Li, Victoria Necroto, Sania D Yousuf, Mariana Chavez-Macgregor, Larrisa Meyers, Eduardo Bruera

Faculty, Staff and Student Publications

Introduction: Patients with advanced cancer and their spousal caregivers who parent minor children report unmet parenting concerns and increased psychological distress. Seeking to address these important supportive care needs, this RCT examined the feasibility, acceptability, and initial evidence for the efficacy of a novel psychosocial intervention.

Patients and methods: Patients with a metastatic solid malignancy and their spouses completed self-reported validated assessments of psychological symptoms and cancer-related parenting outcomes and were then randomized to the parent support intervention or a usual care (UC) group. Both groups were reassessed 6 and 12 weeks later. Dyads randomized to the counselor-led intervention attended …

The Jury Is In: A Comparison Of Perceptions Of Criminal Responsibility Evaluations Completed In Person Vs. Using Videoconferencing Technology, Thomas Ryan Eddy

Electronic Theses and Dissertations Archive

Perceived expert witness credibility is one of many factors that can impact juror decision making behaviors. In cases where the insanity defense has been raised, an expert witness assess the defendant, and may later testify about the defendant’s criminal responsibility (CR). The use of videoconferencing (VC) software to complete forensic mental health assessments has increased. Yet, research examining how jurors perceive the practice of a videoconferenced forensic mental health assessment remains unclear. The present study addressed the dearth in the literature by examining whether the source of assessment (in-person vs. VC) used to conduct a criminal responsibility evaluation impacted perceptions …

Structural Brain Correlates Of Childhood Inhibited Temperament: An Enigma-Anxiety Mega-Analysis, Janna Marie Bas-Hoogendam, Rachel Bernstein, Brenda E. Benson, Samuel E. C. Frank, Kristin A. Buss, Koraly Pérez-Edgar, Giovanni A. Salum, Andrea P. Jackowski, Rodrigo A. Bressan, Anderson M. Winkler

Human Genetics Publications

Objective

Childhood inhibited temperament (cIT) is associated with an increased risk for developing internalizing psychopathology. Neurobiological characteristics identified by structural magnetic resonance imaging (MRI) may elucidate the neural substrates for cIT, but studies are scarce and often focus on particular regions of interest. Moreover, current findings lack replication. This preregistered analysis from the ENIGMA-Anxiety Working Group examined structural brain characteristics associated with cIT using a comprehensive whole-brain approach.

Method

Temperament assessments (behavioral observations, parent/teacher reports or self-reports on cIT before age 13 years) and MRI data (age at scan, 6-25 years) from international research sites (Europe, North America, South America) …

Training Stages And Algorithms Of Multilayer Neural Networks For The Control System, Abdishukurov Maqsudovich Shavkat, Xuecheng Li

Technical science and innovation

The application of neural network technologies in control systems consists of several stages. In technological object control systems, each layer of the multilayer perceptron neural networks is represented using separate transfer functions. The result of synthesizing neural network technology into control systems allows for the rapid solution of many problems. Using neural network technology, it is possible to perform many calculations. Chain rules of neural networks are added this paper. Lots of training algorithms are compared to choose better to train network. Backpropagation neural networks is seen deeply in the last page. Problems of interpolation and extrapolation are solved. Algorithms …

Intelligent Control Of Reducing Energy Consumption And Water Loss In Smart Home Systems, Hakimjon Nasriddinovich Zaynidinov, Damira Farxodovna Hodjaeva, Dhananjay Singh

Technical science and innovation

The article presents an innovative approach to developing an intelligent control system for managing temperature and water level in smart home systems. The proposed method integrates an adaptive PID controller with fuzzy logic algorithms, enabling dynamic adjustment of the PID controller coefficients in real time. The mathematical model of the system incorporates heat balance equations, differential heat transfer relations, and nonlinear models of fluid loss. The adaptive control algorithms developed within the study allow the system to effectively respond to changes in input data.

A comprehensive analysis of the membership functions is conducted, along with adaptive tuning of the PID …

Mic: A Deep Learning Tool For Assigning Ions And Waters In Cryo-Em And Crystal Structures, Laura Shub, Wenjin Liu, Georgios Skiniotis, Michael J Keiser, Michael J Robertson

Faculty, Staff and Students Publications

At sufficiently high resolution, x-ray crystallography and cryogenic electron microscopy are capable of resolving small spherical map features corresponding to either water or ions. Correct classification of these sites provides crucial insight for understanding structure and function as well as guiding downstream design tasks, including structure-based drug discovery and de novo biomolecule design. However, direct identification of these sites from experimental data can prove challenging, and existing empirical approaches leveraging the local environment can only characterize limited ion types. We present a representation of chemical environments using interaction fingerprints and develop a machine learning model to predict the identity of …

An Optimized Model For Identification Of Cerebral Palsy Using Deep Learning, Anjar Ahsan, Hassan Bin Mohammed, Abhilash Maroju, Nurhafizah Moziyana Mohd Yusop, Wan Su Emi Yusnita Wan Yusof, Najjah Salwa Abd Razak, Mohd Arif Dar

Polytechnic Journal

Cerebral palsy (CP), a neurological disorder that affects children and can occasionally result in cognitive problems as well as deficits in motor function can be caused by prenatal, perinatal, or postnatal factors. Each subtype of cerebral palsy (CP), such as spastic and non-spastic cerebral palsy, has distinct symptoms based on the location of the brain lesion and how it affects muscle tone. Individualized therapy and rehabilitation programs are necessary to treat these differences effectively. Therefore, early-stage CP categorization is crucial to ensuring timely and targeted treatment efforts. The functional magnetic resonance imaging (fMRI) of the infant's brain is a helpful …

An Interview With Anthony Viola, Anthony Viola, John Van Kirk

Critical Humanities

Anthony Viola interviewed by John Van Kirk

A Comparison Of Measured Versus Estimated Metabolic Equivalents (Mets) During The Farmer's Carry And Sled Push Exercises On A Commercially Available Step Mill, Colin Miller, Ethan Remotigue, Shane Hammer, J. Jay Dawes, Taylor K. Dinyer-Mcneely

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 6: Issue 1, Article 8, 2025. The Stairmaster 10G ergometer allows users to perform non-traditional movements such as the sled push and farmer’s carry, which involve substantial upper and lower body contributions. Standard MET calculations for stair stepping do not account for this increase upper-body workload, so there is potential for error when aiming to determine exercise intensity based exclusively on estimated METs. The primary purpose of this study is to compare the metabolic and physiological effects of two training modes on the Stairmaster 10G ergometer, specifically evaluating the accuracy of MET values …

Open Access To Humboldt. The Digital Edition Of His Complete Writings, Thomas Nehrlich

Homage to Alexander von Humboldt: Travels to and from Spain Throughout the Centuries / Homenaje a Alexander von Humboldt: Viajes hacia y desde España de todos los siglos

Humboldt published around 750 essays, articles and essays between 1789 and 1859. The Bern Edition of these Complete Writings, which was published in 10 volumes in 2019, has also been available online as a free digital edition since 2021. This article presents its contents and functions, from the bibliography and text display to explanatory commentaries and search functions.

The Astrobiological Figure Of Humboldt As Pioneer In The Rock Varnish Research, Jose Jordan-Soria

Homage to Alexander von Humboldt: Travels to and from Spain Throughout the Centuries / Homenaje a Alexander von Humboldt: Viajes hacia y desde España de todos los siglos

From Humboldt is particularly interesting -and little know- his description of mineral coatings on rocks 200 years ago, reported in his book Personal Narrative of Travels to the Equinoctial Regions of the New Continent during the years 1799-1804, co-written with Aimé Bonpland, for which is considerate the father of rock coating research. On June 5th 1799 set sail from A Coruña -Spain- to Cumaná -Venezuela- beginning five years of expedition. While they explored the Orinoco River system, in th eriver basin waterfalls, Humboldt observed the presence of dark coating depositions. He ascertained a manganese-rich accretion, reporting similar structures in other …

Harnessing Environmentally Healthy Approaches For Plastic Degradation: A Review And Future Perspectives, Marc Chojnacki

Beyond: Undergraduate Research Journal

In the face of escalating plastic pollution, innovative degradation strategies, such as enzymatic degradation, smokeless incineration technology, and biodegradable plastics, are gaining traction. This paper collates comprehensive research on these methods, assessing their environmental impact and operational feasibility. A special focus is placed on the role of technology and its capacity to spark advancements in these degradation strategies as well as to draw on specific research to understand the economic implications of these methods. At the core of this study is the exploration of potential new, inventive degradation methodologies. Through examining methods of green plastic degradation, the study aims to …

Concentration Of Media Ownership

Communication Research Trends

Multi-channel cable, direct broadcast satellite and immediate access to computer data banks promise an immense variety ofinformation at our finger tips. But many are questioning whether this will mean real diversity of public access or simply many more channels in the hands of fewer and fewer industrial giants. Tne rapid introduction of new communication technologies is bringing to the fore all of the old policy dilemmas regarding concentration of economic power in the mass media. In the background are the perennial concerns to guarantee the right to communicate and to encourage diversity of opinion in the debate of public decisions. …

Full Issue: Volume 3, Issue 1 - June 2025

Bone Bulletin

i - Editors’ Note

ii - Foreword by Dr. Alan Hilibrand

7 - Challenges and Concerns of Artificial Intelligence in Shoulder and Elbow by Claude J. Regis

10 - Exploring Robotic-Assisted Total Knee Arthroplasty by Sahil Shah

13 - The Future of Robot-Assisted Surgery in Foot and Ankle Procedures by Sam Duggan

16 - Revolutionizing Spine Surgery: The Potential Role of AI in Enhancing Surgical Workflow and Patient Outcomes by Samuel Ezeonu

21 - Management of Periprosthetic Humeral Fractures Following Shoulder Arthroplasty by Akshay Khanna

24 - Patient Specific Implants in Total Shoulder Arthroplasty by Alexander Zavitsanos

26 - Posterior …

Revolutionizing Spine Surgery: The Potential Role Of Ai In Enhancing Surgical Workflow And Patient Outcomes, Samuel Ezeonu

Bone Bulletin

Introduction

With the growing incidence of degenerative spine pathology¹, surgeons have been tasked to treat more patients than ever. According to Mani et al., the number of single and multilevel fusion procedures are both projected to double over the next 25 years.² In light of this trend, several strategies have been proposed to reduce the resultant burden placed on hospitals and surgeons, while maintaining optimal standards of care. Namely, the use of artificial intelligence (AI) is a growing field that has greatly increased in the last decade. AI has the potential to relieve the cognitive workload placed …

The Future Of Robot-Assisted Surgery In Foot And Ankle Procedures, Sam Duggan

Bone Bulletin

Robot-assisted surgeries are becoming common in most fields of orthopaedics by providing increased accuracy and precision, reducing revision procedures.^1,2 Surgeons specializing in hip and knee, and more recently, spine, have seen tremendous increases in the use of robotics. Still, foot and ankle surgery has had little to no adoption of robotics due to the complex foot and ankle anatomy, in addition to small operating windows; however, usage in spine surgery may be a strong indicator of future use in foot and ankle surgery, as spine surgery similarly requires extreme precision in small operating spaces, with the added benefit of …