Identification Of Functional Non-Coding Variants Associated With Orofacial Cleft, Priyanka Kumari, Ryan Z Friedman, Michael A White, Barak A Cohen, Et Al.

2020-Current year OA Pubs

Oral facial cleft (OFC) comprises cleft lip with or without cleft palate (CL/P) or cleft palate only. Genome wide association studies (GWAS) of isolated OFC have identified common single nucleotide polymorphisms (SNPs) in many genomic loci where the presumed effector gene (for example, IRF6 in the 1q32 locus) is expressed in embryonic oral epithelium. To identify candidates for functional SNPs at eight such loci we conduct a massively parallel reporter assay in a fetal oral epithelial cell line, revealing SNPs with allele-specific effects on enhancer activity. We filter these SNPs against chromatin-mark evidence of enhancers and test a subset in …

Cryo-Em Structures Of A Pentameric Ligand-Gated Ion Channel In Liposomes, Vikram Dalal, Brandon K Tan, Hanrui Xu, Wayland W L Cheng

2020-Current year OA Pubs

Detergents and lipid nanodiscs affect the cryo-EM structures of pentameric ligand-gated ion channels (pLGICs) including ELIC. To determine the structure of a pLGIC in a membrane environment that supports ion channel function, we performed single particle cryo-EM of ELIC in liposomes. ELIC activation and desensitization were confirmed in liposomes with a stopped-flow thallium flux assay. Using WT ELIC and a non-desensitizing mutant (ELIC5), we captured resting, activated, and desensitized structures at high resolution. In the desensitized structure, the ion conduction pore has a constriction at the 9' leucine of the pore-lining M2 helix, indicating that 9' is the desensitization gate …

V2b Neurons Act Via Multiple Targets To Produce In Phase Inhibition During Locomotion, Mohini Sengupta, Alaina Bertram, Shuyu Iris Zhu, Geoffrey J Goodhill, Martha W Bagnall

2020-Current year OA Pubs

Spinal interneurons shape motor neuron activity. Gata3

Self-Compassion And Openness To Experience: A Meta-Analysis Of Relations, Jordan Moreno

Electronic Theses and Dissertations Archive

Abstract This meta-analysis sought to determine the overall association between self-compassion and openness to experience across the existing body of literature, as well as to add to the currently limited research on the associations between the individual subscales of self-compassion and openness to experience. A systematic search was conducted throughout several databases, including PsychINFO, ERIC, SCOPUS, and WorldCat Dissertation Search, using the following commonly used search terms: self-compassion, self compassion, Self-Compassion-Scale, open, openness, Big Five, HEXACO, and NEO.The study carefully extracted a total of 122 unique effect sizes (Pearson’s r) from 37 different samples, drawing on data from a combined …

Correctional Psychology And Training Implications: A Mixed Analysis Of Trainee Knowledge And Application Of Ethical Dilemmas In Corrections, And A Closer Look At The Experience Of Support From Generalist Training, Alyssa A. Hoyt

Electronic Theses and Dissertations Archive

Correctional psychology, a subfield of psychology, has long been comprised of its own distinct purpose, focus, and competencies. Yet correctional psychology remains unrecognized today as a formal American Psychology Association (APA) specialization. Unlike forensic psychology, without an APA specialization, and subsequent structured training standards, scholars have argued that correctional mental health professionals may be ill-prepared to navigate unique ethical dilemmas inherent to the correctional environment. The present mixed analysis study aimed to contribute to this discussion by assessing psychology trainees’ ability to respond to hypothetical ethical dilemmas in a manner consistent with correctional environments, and whether prior correctional experience/ exposure …

Specialty Grand Challenge: Existing Issues And Emerging Frontiers In Renal Endocrinology, A. T. M. Emdadul Haque, Mohammed S. Razzaque

School of Medicine Publications

We are currently in an exciting time to advance the field of renal endocrinology. There has never been a more favorable time to study the molecular and cellular mechanisms underlying renal hormone functions in physiology, pharmacology, and pathophysiology. The availability of advanced research tools provides unique opportunities to dissect the complex regulatory roles of renal hormones. The kidneys are vital organs in the human body; each one is composed of approximately one million functional nephrons. Understanding the precise roles and regulation of kidney-derived hormones and hormones that exert endocrine effects on the kidneys will help in preventing or delaying various …

Calibration Of Detectors For The Tomographic Ionized-Carbon Mapping Experiment, Tessalie A. Caze-Cortes

Theses

Observations of the intensity of the sky at millimeter (mm) wavelengths require accurate calibrations for the spectrometers to work with radio telescopes. However, calibrating is a complex and lengthy process for sensitive detectors that catch single photons. To improve efficiency in locating defective detectors and optimizing bias current, my research involves taking data from previous lab characterizations and creating an algorithm that analyzes and plots the code of all 1920 detectors. This thesis will discuss the importance of mm-wavelength intensity mapping and the questions the TIME research team aims to address. Also, a detailed description of mechanical and computational components …

An Example Where Taking An Additional Observation Doesn't Help, Stephen Portnoy, James Stein

Mathematics and Statistics Faculty Publications and Presentations

It seems intuitively obvious that no part of a random sample should be discarded. However, for most students, the first formal justification of this idea is when sufficiency is introduced in an introductory statistical theory course. Students are often left with the idea that conditioning on the sufficient statistic always improves inference, even though the formal theory only says that for any statistical procedure there is one depending on the sufficient statistic that is no worse. Here we present an example on comparing two coins based on two consecutive tosses, where the optimal probability of guessing which coin has the …

Maternal Hyperleptinemia Alters Placental Transcriptome And Progesterone Regulation Without Affecting Early Equine Fetal Growth, Lucinda L. Thorburn

LSU Master's Theses

While consequences of equine obesity are well defined, the extent to which persistent hyperleptinemia and accompanying leptin (Lep) resistance affect the fetal-maternal environment warrants further exploration. This study compared endocrine, fetal, placental, and uterine parameters during early pregnancy (through day 70) in mares with elevated leptin versus normal leptin (NL) concentrations. Fourteen mares were classified as either NL (n = 6; Lep 0.9 ± 0.3 ng/mL), moderate leptin (ML; n = 4; Lep 3.0 ± 0.3 ng/mL), or high leptin (HL; n = 4; Lep 5.8 ± 0.7 ng/mL) based on annual plasma leptin. Mares were artificially inseminated and induced …

Dose Characterization Of Galactic Cosmic Rays In The Human Brain: A Phits-Based Study With A Segmented Anatomical Phantom, Shanice N. Manning

LSU Master's Theses

Astronauts aboard the International Space Station (ISS) are chronically exposed to a complex space radiation environment composed of galactic cosmic rays (GCR), solar particles, and Earth's trapped radiation. These high-energy particles interact with spacecraft shielding, producing secondary particles that can penetrate inside and deposit energy in sensitive tissues. Although animal studies have been useful in assessing space radiation risks, anatomical and physiological differences limit their applicability to human anatomy especially neuroanatomy. To address this gap, we developed a computational framework to model radiation dose distribution within the human brain using Monte Carlo simulations in Particle and Heavy Ion Transport code …

Anxiety's Impact On Autism Spectrum Disorder Symtomology: An Investigation Into The Relationship Between Two Comorbities, Michaela Brown

LSU Doctoral Dissertations

Autism spectrum disorder (ASD) has been found to be frequently comorbid with many medical and psychological disorders, one of which is anxiety disorders. Research has shown that, when anxiety is present within ASD, various areas of the child’s functioning may be impacted, such as ASD symptom severity, emotional regulation skills, adaptability, social skills and daily living skills. The current study aimed to investigate this relationship of anxiety and ASD. First, within a sample of children and adolescents with ASD, the magnitude of the correlation between specific ASD symptoms parent-reported anxiety was compared to determine if certain ASD symptoms were more …

For Us, By Us: A Digital Ethnographic Exploration Of Black Podcasts, Intimacy, & Sexual Pleasure, Dominique C. Dillard

LSU Doctoral Dissertations

Sociological literature written about Black folks interprets their sexual behavior as unhealthy, risky, and non-normative. Black people are seldom acknowledged as humans, so it is not surprising to discover a discourse that does not portray them as sexual subjects. Studies examining Black sexual subjectivity through white and colorblind ideologies dominate the discussion, reproducing racist discourse historically ascribed to Black bodies. Guided by Audre Lorde’s concept of erotic as power, I document an alternative epistemology about Black sexuality. I argue the construction of Black sexuality must focus on sexual selfhood to grasp how this population conceptualizes and makes sense of their …

Digital Forensics And Ai: Artifact Analysis And Using Ai In The Forensics Domain, Clinton Joel Walker

LSU Doctoral Dissertations

Digital Forensics (DF) is a field of forensic science focusing on the acquisition, authentication, and analysis of digital evidence while maintaining integrity of that data. DF analysts use forensic tools to parse large volumes of data for investigations and depend on them for identification of pertinent digital evidence in vast amounts of data. Keeping up with innovations and ever-expanding data volumes is a constant challenge for these investigators. The prevalence of Artificial Intelligence (AI) in everyday computing is rapidly expanding, with the use of Machine Learning (ML) and Large Language Models (LLM)s becoming increasingly commonplace. Innovations in technology bring new …

Towards Leveraging Social Media Data For Fostering Collaborations Among Non-Profits, Monazil Chowdhury

LSU Doctoral Dissertations

Nonprofit organizations serve a crucial role in tackling a wide range of significant social, environmental, and economic issues. But it is often hard to get a clear picture of their work because their information is spread out and it is difficult to see how they are collaborating. To address this issue we developed a web-based tool to collect scattered data—from a variety of sources, such as the IRS, social media, and the Census, into one easy-to-use resource. The tool begins by taking IRS records and geocoding each nonprofit’s physical address With its coordinates. It then retrieves census tract information from …

Human Development, Inequality, And Their Associations With Brain Structure Across 29 Countries, Vicente Medel, Luz M. Alliende, Richard Bethlehem, Jakob Seidlitz, Grace Ringlein, Celso Arango, Aurina Arnatkevičiūtė, Laila Asmal, Mark Bellgrove, Anderson M. Winkler

Human Genetics Publications

Background: The macro-social and environmental conditions in which people live, such as the level of a country’s development or inequality, are associated with brain-related disorders. However, the relationship between these systemic environmental factors and the brain remains unclear. We here aimed to determine the association between the level of development and inequality of a country and the brain structure of healthy adults.

Methods: We conducted a cross-sectional study pooling brain imaging (T1-based) data from 145 magnetic resonance imaging (MRI) studies in 7,962 healthy adults (4,110 women) in 29 different countries. We used a meta-regression approach to relate the brain structure …

Understanding The Chemical And Electronic Properties Of Sub-Monolayer Tio₂ On High Surface Area Silica For Jet Fuel Synthesis Applications, Mark A. Isaacs, Charalampos Drivas, Arthur Graf, Sasha Kroon, Santosh Kumar, Junxi Liu, Antonio Torres‐Lopez, Cameron Price, Edward Garland, Ines Lezcano‐Gonzalez, Christopher M. A. Parlett, Vannia C. Dos Santos‐Durndell, Lee J. Durndell

School of Geography, Earth and Environmental Sciences

2.5% of global carbon emissions result from air travel, underscoring the need for sustainable aviation fuels (SAF) derived from second-generation lignocellulosic biomass to enhance the green credentials of the aviation sector. This study demonstrates the first solvent-free photocatalytic conversion of furfural (FAL) and cyclopentanone (CPO) to produce 2,5-bis(2-furylmethylidene)cyclopentanone (F2Cp), a jet fuel precursor, using Ti-SBA-15 catalysts, synthesized via alkoxide grafting and controlled titanium surface coverage. Sub-monolayer titania films on SBA-15 supports are achieved with tuneable Ti content, confirmed by XPS (X-ray photoelectron spectroscopy), UPS (ultraviolet photoelectron spectroscopy), REELS (reflectance electron energy loss spectroscopy), ISS (ion scattering spectroscopy), and Raman analysis. …

Spase: Spatially Resolved Pathology Scores Using Optimal Transport On Spatial Transcriptomics Data, Mohammad Nuwaisir Rahman, Mohammed Abid Abrar, Vikram Rakesh Shaw, James F Martin, M Saifur Rahman, Md Abul Hassan Samee

Faculty, Staff and Students Publications

Pathological events often impact tissue regions in a spatial variable manner, making it challenging to identify therapeutic targets. Spatial transcriptomics (ST) is a powerful technology to map spatially variable molecular mechanisms, yet suitable analytical methods have been lacking. We introduce SPaSE (Spatially-resolved Pathology ScorE), an optimal transport-based algorithm to compare ST data from diseased and control tissues. SPaSE computes a “pathology score” for each spot in the diseased sample, quantifying the pathological impact at that spot. In post-MI (myocardial infarction) mouse hearts, these scores delineated zones that matched independent expert annotations. Modeling pathology scores from gene expression revealed signatures predictive …

Examination Of The Criterion-Related Validity Of The Scales For Assessing Emotional Disturbance – 3rd Edition, Corey Pierce, Jacqueline Huscroft-D'Angelo, Jessica Wery, Brad Uhing, Jodie Martin, Kara Loftin

Journal of Educational Research and Innovation

In this study, we sought to determine if the Scales for Assessing Emotional Disturbance – Third Edition (SAED-3; Epstein et al., 2020) demonstrated adequate validity using criterion validation techniques. The associations between the SAED-3 subscales and composite scores were examined in relation to similar scores from the Behavior Assessment System for Children – Second Edition (BASC-2; Reynolds & Kamphaus, 2004) and the Strengths and Difficulties Questionnaire (SDQ; Goodman, R., 1997). SAED-3 ratings were conducted with either the BASC-2 or SDQ with 121 students ages 6 to 17 years. The overall criterion prediction evidence of …

Newsclipping, Legislators To Conduct 4th Hearing

Eartha M. M. White Textual Material

News clipping: Duval legislative delegation to hold public hearing on proposed legislation. Members of delegation list. Includes handwritten notations on Barnett National Bank deposit slip: City 10,000 C W M, County 10,000, 5,000 museum. Undated.

Intercultural Communication

Communication Research Trends

For the survival and development of important human values, the study of intercultural communication may be one of the critical areas of communication research. One has only to witness "Kojak" and "Starsky and Hutch" bouncing off satellites into the intimacy of minds and homes in cultures of India and Thailand to realize this. Vendors of communication technology are rushing to pen a Pandora's box of influences which may erode cultural ideals created over thousands of years. Once again we are not prepared to cope with the human and social implications of communication technology.

But the focus of research in intercultural …

Crucial Components Of An English Literacy Curriculum For Moroccan Adults, Philip J. Byler Mr.

Capstone Collection

This research paper examines the lived experiences and expertise of Moroccan teachers of English in teaching English literacy to Moroccan adults. Current research indicates that approximately 33 percent of Moroccan adults are illiterate. While there is research highlighting the need for adult literacy and its benefits, there is a lack of studies on how to develop an effective English literacy curriculum for Moroccan adults. Additionally, existing research underscores the growing importance of English in Morocco and the increasing desire among Moroccans to learn English.

Using a qualitative approach, this study explores the crucial components of an English literacy curriculum based …

Seoul’S Soul: A Study Of Drag Culture’S Influence On Queer Young Adult’S Education In South Korea, Ian Sollender

Capstone Collection

Drag performance has long been considered a site of artistic expression, political resistance, and community-building within LGBTQ+ spaces. This capstone research project explores the educational impact of drag culture in Seoul, South Korea, with a particular focus on how drag performances serve as a pedagogical and educational tool that challenges gender norms, fosters queer community, and provides a platform for political discourse. Through qualitative analysis of participant observation, bilingual Korean and English survey responses, and in-depth English interviews with drag performers, performance organizers, and audience members, this research highlights the ways in which drag can function as a site of …

Qualitative Tools To Enhance Data Analysis From Diverse Sources Of International Education Policy In Order To Create A More Perfect Evaluation Toolset, Robert J. Schulenburg

Capstone Collection

Abstract

This project proposes a new protocol for implementing meta-synthesis as a research tool. Meta-synthesis allows researchers to combine data sets from multiple sources that appear unconnected; it allows data sets to be extracted from multiple domains and knowledge banks that present as being unable to be combined or cross-transferable. This project presents a protocol designed to guide meta-synthesis which was used to extract critical relevant data from the Sustainable Development Goals (SDGs) related to inclusive education and inclusive work and rehabilitation policies and practices. The project shows with deliverables how, with this data in hand, newly aggregated extracted data …

Shining In Times Of Crisis: How Refugee Women Display Leadership And Transform Hardship, Laura Iorg

Capstone Collection

Abstract

There are currently approximately 122.6 million people displaced globally (UNHCR, 2024). This figure includes 43.7 million refugees (UNHCR, 2024). Nearly half of them are women. This qualitative study examined the following questions: How do women manifest leadership and agency in refugee situations? Subquestion: How do women contribute to peace, transformation, and healing through that leadership and agency? Five different individuals who had worked with women refugees for at least two years were recruited for the study. Two data collection instruments were employed: a preliminary survey and a structured interview. The study focused on the lived experiences of refugee women …

Combat Motivation And Swift Trust In Canada’S Battle Of Hong Kong, 1941, Robert C. Engen, Maxwell Putnam

Canadian Military History

Abstract: In December 1941, the British Crown Colony of Hong Kong was the site of a doomed last stand, when the Imperial Japanese Army assaulted the British enclave near-simultaneously with the strike on Pearl Harbor. Among Hong Kong’s multinational defenders were two battalions of Canadian infantry, designated “C Force.” They held out for a significant period and inflicted heavy casualties upon the Japanese, despite the fact that the Canadians were under-trained, under-equipped and fighting a battle that could not be won. This article is the first major study of combat motivation in the Battle of Hong Kong, taking the Canadian …

“Border Line Pilots”: Rcaf Aircrew, Crash Investigations And No. 22 Otu, Wes Cross

Canadian Military History

Abstract : In 1941, RAF Bomber Command Operational Training Units (OTU) in the United Kingdom were created to produce crews for the bomber offensive from graduates of the British Commonwealth Air Training Plan. Of the 4,000 RCAF deaths attributed to non-operational accidents, 1,498 occurred in this OTU phase. A study of No. 22 OTU accident reports, where the largest number of RCAF training fatalities occurred, provides insight into the stated official causes and underlying issues of the high accident rate. Of more recent interest is how one No. 22 OTU 1944 aircraft crash site decades later became a center of …

"That Movie Changed Me!" Effect Of Induced Mood On Story Interpretation, Rachel Deborah Thayer

2025 Symposium

Studies have found that mood can affect a variety of aspects of cognition, such as memory, comprehension, and decision making. In one such study, participants identified with the character that reflected their hypnotically induced mood, and in another, story endings that were incongruent with the film clip-induced mood were more difficult to process. In the current study, film clips were used to induce moods, and participants were asked to write an ending to an ambiguous story. The prediction is that participants’ completions will reflect their induced mood. To date, 25 Eastern Washington University undergraduate students have been recruited and screened …

A Hybrid Ai-Powered Voice-Enabled Medical Practice Assistant With Dynamic Triage Routing And Multi-Modal Patient Interaction, Patrick Proctor

Defensive Publications Series

We present a novel implementation of a voice-enabled medical practice virtual assistant that combines real-time speech processing, intelligent medical triage routing, and multi-modal patient interaction capabilities. Our system employs a hybrid AI architecture that dynamically selects between different language models based on query complexity classification, reducing operational costs while maintaining high-quality responses for complex medical inquiries. The system incorporates a deterministic medical triage decision tree based on established nursing protocols, enabling automated routing of urgent cases while maintaining HIPAA compliance. Additionally, we introduce an innovative multi-step interaction pattern for location-aware services, seamlessly transitioning between voice input, location detection, and turn-by-turn …

Noda News Summer 1995

New Orleans Dental Association News

New Orleans Dental Association (NODA) News includes regular columns with regional news impacting the New Orleans membership including: columns from the President and Executive Director, feature articles relating to the field of dentistry, association events and upcoming activities, component news, continuing education opportunities, and classifieds.

The volume number for this item was mislabeled at the time of publication. It has been moved to the correct volume in ADA Commons but retains the original misprint.

Additionally, due to site configuration limitations this item has been labelled Issue 10 in ADA Commons. See the recommended citation below for details.

Examining Weight Bias Attitude Changes After Exposure To A Brief Photovoice Assignment, Gretchen L. George, Hillary L. Roberts, Kristin Rose, Madison Clemens, Kate G. Burt

Journal of Dietetic Education

Weight bias is present among pre-health professional students (e.g., nutrition, dietetics, nursing, physical therapy, medicine). Educators need support and guidelines about how to enhance learning through engaging assignments while also meeting accreditation requirements. This pilot study examined the impact of an innovative weight bias assignment using photovoice and reflection within existing nutrition education courses, measured through pre-post assessments from the Fat Attitudes Assessment Toolkit. While not all subscales showed significant change, improvements in the Fat Acceptance and Attribution Complexity Composites suggest these methods may be effective in shifting attitudes about fatness. Further research is needed to assess the long-term impact …