Digital Commons Network^™

Associations Of High Attenuation Area-Related Proteomic Biomarkers With Fibrotic Or Subpleural Interstitial Lung Abnormalities, John S Kim, Catherine L Debban, Daniel E Guzman, Riley T Hannan, Mary Salvatore, Claire Mcgroder, David Zhang, Anna J Podolanczuk, Daniel A Duprez, Shwu-Fan Ma, Yong Huang, Jeffrey M Sturek, Stephen S Rich, Jerome I Rotter, Rajat Deo, Ruth F Dubin, Janelle Vu Pugashetti, Jennifer M Wang, Meilan K Han, Justin M Oldham, Imre Noth, Prescott G Woodruff, Victor E Ortega, Julie C Fanburg-Smith, Edward B Stelow, Christopher A Moskaluk, Eric A Hoffman, Christine Kim Garcia, Russell P Bowler, Peter Ganz, R Graham Barr, Ani Manichaikul

Faculty, Staff and Student Publications

No abstract provided.

A Randomised Controlled Trial Of Verbal Guidance Versus Verbal Guidance Supplemented By A Photographic Aid For Bystander Identification Of Intramuscular Tranexamic Acid Injection Sites In A Simulated Road Injury Scenario, Tim Nutbeam, Emily Foote, Lauren R. Rodgers, Jessica Thomas-Mourne, Rob Fenwick

Peninsula Medical School

Background: Non-compressible haemorrhage is a leading cause of preventable death following road injury. Tranexamic acid (TXA), when administered early, improves survival. Intramuscular (IM) administration offers a feasible route for early administration by lay bystanders. However, the ability of bystanders to correctly identify safe IM injection sites remains unclear. This study aimed to evaluate whether verbal guidance supplemented by a photographic aid improves the accuracy of site identification in a simulated road injury scenario. Methods: In this randomised controlled trial, 64 lay participants were recruited on a university campus and randomised to receive either (1) verbal guidance alone or (2) verbal …

Effective Enforcement Of Laws Prohibiting Underage Tobacco Product Sale Is Needed, Harold J Farber

Faculty, Staff and Students Publications

No abstract provided.

Pre_And Postoperative Evaluation Of Patients With Lumbosacral Disc Herniation (L4l5, L5s1)By Neurophysiological, Radiological And Clinical Assessment., Ahmed Al Atraqchi, Duraid Al Badawi

Iraqi Postgraduate Medical Journal

AbstractObjective: Pre and postoperative evaluation of patients with lumbosacral disc herniation by neurophysiological, radiological and clinical assessment.Patient and method: This prospective and retrospective cohort study was conducted at Saad Al-Witry neuroscience teaching hospital in Baghdad in the period extended from January 2017 to October 2023. The study included a total number of 1000 cases gathered from a neurosurgical team specialized in spine cases handling. The selection of cases was based on clinical and neurological examination. In whom medical therapy failed to control patients' symptoms.The patients were observed during their initial visit to the clinic, the day of the procedure, 2 …

Violence Of Husbands Against Reproductive Age Wives During Covid-19 Pandemic, Zainab Aljoori, Mushtaq Hashim

Iraqi Postgraduate Medical Journal

Background:The COVID-19 pandemic has led to a surge in domestic violence, affecting women's physical and mental health through direct and indirect means. A history of violence can increase the risk of various diseases, and severe abuse can persist even after the violence ceases.MethodsA cross-sectional web-based survey that included 500 women calculated according to Roasoft calculator based on previously published Iraqi studies , it was convenience sampling and was conducted between June and September among 15-49 year old Iraqi women, recruited via social media platforms, and completed until a sample size of 500 forms was collected.ResultsThe study found that psychological violence …

The Correlation Between Brain Mri And Mrv Findings And Csf Pressure Value In Idiopathic Intracranial Hypertension, Ail Mohsin, Hasan Al-Hamadani, Noor Hummadi

Iraqi Postgraduate Medical Journal

BackgroundIdiopathic intracranial hypertension is a clinical entity characterized by increased cerebrospinal fluid pressure of unknown cause. The diagnosis depends on raised intracranial pressure, and the absence of identifiable causes.AimTo investigate the correlation between CSF pressure value and radiological findings based on cranial MRI and MRV in patients with idiopathic intracranial hypertension.MethodPatients with IIH who underwent brain MRI and MRV between June – 2019 to March– 2022 were evaluated. A total of 46 patients were assessed by one expert radiologist. The radiological score was based on the following findings: Partially empty Sella, Posterior displacement of the stalk, Flat posterior globe, Intra-ocular …

Edgeworth Expansions In Curved Cross Section Autoregression, Peter C.B. Phillips

Cowles Foundation Discussion Papers

Edgeworth expansions are developed for the finite sample distribution of the least squares estimator in a time series parametric first order autoregression with Hilbert space curves of cross section data. The main result extends to this functional data environment the Edgeworth expansion in the corresponding scalar time series AR(1). In doing so, the results show how function-valued cross section data, and hence general forms of cross section dependence, affect the finite sample distribution of the serial correlation coefficient. Autoregressions with functional fixed effect intercepts are included and the results therefore relate to dynamic panel autoregression with individual effects. The primary …

Concussion Knowledge, Attitudes, And Behaviors: A Comparison Study Of Youth Athletes And Their Parents, Summer D Ott, Sukhnandan K Cheema, Holden Axel, Seema S Aggarwal, Natalie R Parks, Nikhil Gattu, Philip Schatz

Faculty, Staff and Student Publications

Objective: Given the rising participation in high school athletics and the concerning trend of underreporting concussions, this study aims to identify and compare factors influencing sports-related concussion (SRC) awareness and reporting among youth athletes to their parents.'

Methods: Surveys were completed by 239 student-athletes (ages 13-19) and their parents, using a modified Rosenbaum Concussion Knowledge and Attitudes Survey-Student Version (RoCKAS-ST) and demographic questionnaires. Statistical analyses, including paired sample t-tests, ANOVAs, and Spearman's correlations, compared knowledge and attitudes between groups and examined demographic influences.

Results: Parents showed significantly higher concussion knowledge (CKI: t(230) = 5.18, p < .001) and safer attitudes (CAI: t(230) = 10.62, p < .001) than their children. Knowledge scores varied significantly by race and socioeconomic status, with White parents scoring higher than Hispanic and African American parents (F(3,224) = 8.97, p < .001). Child knowledge scores also differed by race (F(4,223) = 3.73, p = .006) …

Leveraging After School Programs As Resources To Support Adolescent Health And Wellbeing Within Underserved Communities: A Qualitative Study, Olivia Staples

Theses and Dissertations

Over the past decade, youth have shown a consistent rise in stress, major depression, anxiety, and suicide, with underserved youth (low-income, minoritized communities) at greatest risk of exposure to chronic stress, related outcomes, and less access to health services (APA, 2017). Afterschool programs (ASPs), which serve as important resources in underserved communities, can be a critical support for youth health and well-being (Afterschool Alliance, 2019). However, few studies have examined ways in which ASPs address the challenges underserved youth face across their ecosystem to promote youth resilience (Jones & Deutsch, 2011). Using qualitative interview data from staff and youth across …

​​​Creating A Resident And Fellow Scholarly Activity Tracking Tool In A Large Academic Health System: A Dissertation In Practice​, Elyse Anne Wieszczecinski

Theses and Dissertations

Documenting and reviewing resident and fellow scholarly activity within a sponsoring institution can be a laborious task. With multiple lines of information coming from a wide variety of sources, this problem of practice implemented the Information Systems Success Model to help develop a database by which this information can be collected in a way that is efficient while maintaining the need for a user-friendly product. While other healthcare entities have also incorporated this model into their scholarly activity collection, these are still individual needs of the sponsoring institution and its constituents to consider when adapting the strategy. Using an improvement …

Thesis: Comparing Functional And Effective Brain Connectivity Metrics For Eeg, Diksha Srishyla

Theses and Dissertations

Background:Brain connectivity measures have been used to study communication between brain regions using electroencephalography (EEG). Functional and effective connectivity estimate the synchronization and the flow of information between regions, respectively. However, findings from studies using different measures to investigate similar connections do not converge. To guide the selection of functional and effective connectivity measures in future studies, we systematically compared a set of measures in the context of resting state EEG. We examined four functional connectivity metrics (coherence (Coh), the imaginary part of coherence (imCoh), the corrected imaginary part of phase lagged value (ciPLV), the debiased weighted phase-locking index (dwPLI)) …

Ai-Driven Autonomous Manufacturing: A Novel Taxonomy, Vision-Guided Planning, And Diversity-Aware Active Learning Frameworks, Ibrahim Yousif

Theses and Dissertations

Manufacturers face two opposing challenges: the escalating demand for customized products and the pressure to reduce lead times. Current manufacturing equipment, although reliable, operates at the limits of its technology and lacks adaptability to dynamic environments. This trade-off has been described as the optimal degree of automation, a threshold beyond which further automation incurs more cost than benefit. Smart manufacturing has introduced adaptive, data-driven systems, but many deployments still lack the contextual adaptability and autonomous decision-making required to handle unplanned disruptions. This underscores the need for intelligent, autonomous systems capable of real-time adaptation without costly reconfiguration, minimizing human intervention during …

Towards Accurate First-Principles Modeling In Heterogenous Catalysis: Ethane Dehydrogenation And Hydrogenolysis Over Pt Catalysts, Mubarak Ayo Bello

Theses and Dissertations

First-principles modeling has become central to heterogeneous catalysis research, offering mechanistic insight and guiding catalyst design, yet conventional approaches often struggle to accurately describe complex catalytic systems due to methodological uncertainties, simplified assumptions, and the structural diversity of nanoparticle catalysts. This dissertation addresses these challenges using ethane dehydrogenation (EDH) and hydrogenolysis (EH) over platinum catalysts as model systems. The first study benchmarks density functional theory (DFT) functionals against the random phase approximation (RPA) for the EDH network on Pt(111), identifying cost-effective functionals and demonstrating the efficiency of BEEF-vdW ensembles for capturing functional uncertainty. The second study (addressed in prior work) …

Multi-Perspective Feature Learning For Facial Expression Recognition In The Wild, Xiangyu Hu

Theses and Dissertations

With the rapid progress of deep learning, Facial Expression Recognition (FER) has seen substantial improvements in performance, particularly “in the wild” meaning real world conditions. Despite these advances, most existing methods extract features from facial images as the sole emotional cues, which limits the model’s ability to capture the full complexity of human emotional expressions.

In reality, facial expressions are composed of diverse and multi-perspective information, including appearance-based cues and geometric structural deformations due to activations of facial muscles. Depending exclusively on one type of representation may fail to exploit the complementary nature of these cues, an issue that becomes …

New Approaches On Source Coding For Quantum Stochastic Sources And Implementation Of Quantum Fanout Gate, Rabins Wosti

Theses and Dissertations

The accurate computation of advanced quantum algorithms like Shor’s integer factorization, quantum phase estimation (QPE), and the quantum Fourier transform (QFT) requires quantum circuits of considerable size and depth. It is difficult to achieve reliable computation with deep quantum circuits due to the limited coherence times of the current noisy quantum devices. The quantum fanout gate is known to be a powerful primitive for reducing the depth of many quantum circuits (Høyer and Špalek 2003; Gottesman and Chuang 1999). Shallow or constant-depth quantum circuits are desirable for both near-term and fault-tolerant quantum computations as they reduce noise and allow faster …

Investigating The Influence Of Instructional Strategies On The Development Of Procedural And Conceptual Knowledge In Advanced Algebra Ii Students, Maura Frances Yinger

Theses and Dissertations

This mixed-methods action research study investigated the influence of instructional strategies shown to improve students’ procedural and conceptual understanding in a rational expressions and equations unit in Advanced Algebra II. The instructional strategies used in the study include comparing, self-explaining, and exploring before instruction. The students (N=27) completed a pre-test and a post-test, both of which were followed by questions asking students to justify their responses on two questions. All students also responded to six digital self-explanation journal prompts. Randomly selected students were placed into three homogenous groups to participate in performance task observations. Analysis of the data …

Beyond The Bipolar: Allowing Satisfaction And Dissatisfaction To Coexist, Dustin J. Souders, Yixiu Yu

Publications

Copyright © 2025 Souders and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).

Building Services Engineering September/October 2025

Building Services Engineering

No abstract provided.

Decorin Evokes A Pro-Lysosomal Pathway In Lymphatic Endothelial Cells, Gabriel J. Pascal, Dipon K. Mondal, Sadie Kim, Christopher Xie, Devanarayanan Siva Sankar, Jörn Dengjel, Renato V. Iozzo

Kimmel Cancer Center Faculty Papers

The lymphatic system is critical to the body's immune and circulatory system, and lymphangiogenesis, the development of new lymphatic vessels from pre-existing ones is a significant process capitalized upon by cancer during tumorigenesis. Decorin is a small leucine-rich proteoglycan which we have previously shown to be anti-tumorigenic and a suppressor of lymphangiogenesis. We have also shown that decorin exercises its anticancer properties through its ability to evoke autophagy. Through a comprehensive and unbiased proteomic analysis, we explored the implications of decorin exposure on protein expression within mouse lymphatic endothelial cells. We discovered that decorin enriches several protein pathways, notably proteasomal …

The Association Between Inflammatory Bowel Disease And Ischemic Heart Disease: A Retrospective Cohort Study, Mahmoud H. Mosli, Dima M. Alsulami, Yara K. Alghamdi, Abdullah S. Badahdah, Asmaa H. Alhibshi, Thamer M. Alamri, Maan S. Alkhattabi, Khames T. Alzahrani, Hadeel A. Alsufyani, Omar I. Saadah

Saudi Medical Journal

ABSTRACT Objectives: To evaluate the association between Inflammatory bowel disease (IBD) and Ischemic heart disease (IHD). Methods: A retrospective cohort analysis included patients with and without IBD seen at the outpatient gastroenterology clinic of a large tertiary care hospital between January 2015 and October 2022. The primary outcome was the association between IBD and IHD, and the secondary outcome was predictors of IHD in patients with IBD. Results: The study included 400 patients; 291 were IBD patients, and 109 had other non-inflammatory GI disorders. The IBD group displayed significantly lower rates of hyperlipidemia (8.6% vs. 30.3%, p <0.001), diabetes mellitus (DM) (10% vs. 24.8%, p <0.001), and hypertension (11.7% vs. 32.1%, p <0.001) compared to the non-IBD group. Only 2.7% (n=8) of IBD patients developed IHD. Logistic regression analysis did not demonstrate a significant association between IBD and IHD ( p =0.932). Among classical risk factors, only hypertension (OR: 26.2, 95% CI: 2.14–661, p =0.016) and hyperlipidemia (OR: 10.5, 95% CI: 1.32–132, p =0.0405) significantly increased the risk of developing IHD among patients with IBD. Conclusion: In this cohort, there is no increased risk of developing IHD in patients with IBD compared to non-IBD patients.

Characterization And Management Of Pain Across Phases Of Intraosseous Infusion In Emergency Department Patients With Non-Cardiac Arrest, Aiping Shi, Juan Chen, Xiaowei He, Chunyan Chen, Ming Sun, Wei Li, Wenxia Xu, Wei Yang, Xiaoqin Han

Saudi Medical Journal

ABSTRACT Objectives: To identify risk factors for moderate-to-severe pain during intraosseous infusion (IOI) in non-cardiac arrest patients in the emergency department (ED). Secondary aims include evaluating pain trajectory across procedural stages and assessing the efficacy of a personalized pain management strategy. Methods: This mixed-methods study analyzed 220 ED patients undergoing IOI (150 retrospective, 70 prospective). The prospective cohort was randomized to standard care (n=35) or personalized pain management (n=35). Pain was quantified using the numeric rating scale (NRS) and critical-care pain observation tool (CPOT). Results: During puncture, 35.33% (53/150) reported no/mild pain. Pain severity peaked during flushing, with 73.33% (110/150) …

Feasibility And Utilization Of Point-Of-Care Ultrasound Devices In A Prehospital Setting In Riyadh, Saudi Arabia, Murdhi H. Alanazi, Abdulaziz A. Alrabiah, Ebrahim A. Algosaibi, Noof H. Alzahrani, Muhanna A. Alanazi, Mansour M. Aldhafeeri, Hani A. Albrahim, Abdulmajeed M. Mobrad

Saudi Medical Journal

ABSTRACT Objectives: To evaluate the utility of point-of-care ultrasound (POCUS) devices in prehospital care in Saudi Arabia. Furthermore, the impact of POCUS training on paramedics’ knowledge, confidence in use, and attitudes toward POCUS devices was assessed. Methods: Thirty-seven paramedics who were engaged in providing prehospital emergency care were selected. A quasi-experimental pre-test and post-test study was conducted between February 5 and March 20, 2025. Participants underwent a comprehensive POCUS training involving theoretical lectures, hands-on sessions, and simulation-based exercises. Results: A significant improvement in overall POCUS knowledge, confidence in use, and diagnostic accuracy were noted on the post-test survey. Pre-test knowledge …

A Data-Driven Framework For Optimal Retail Store Location, Ming Hui Tan

Dissertations and Theses Collection (Open Access)

This study develops a data-driven framework for optimal retail store location planning that integrates road network analysis, mobility data and optimization techniques. By addressing the limitations of traditional approaches that rely on outdated census data and manual site selection, this research offers a scalable and adaptable solution for retail expansion in diverse urban environments. Chapters 1 and 2 establish the foundational context and theoretical underpinnings of this research. Chapter 1 introduces the research problem and motivation, highlighting the limitations of existing approaches and defining three key research objectives: automating candidate site identification, improving footfall estimation, and developing a scalable multi-site …

Harnessing Se Community Knowledge For Developer-Centric Code Intelligence, Chengran Yang

Dissertations and Theses Collection (Open Access)

The integration of Large Language Models (LLMs), particularly those tailored for programming tasks—referred to as code LLMs—has created novel opportunities to enhance developer productivity. These advanced models automate routine and repetitive coding tasks, such as code generation and debugging, and enable faster prototyping and more efficient problem-solving. Despite these remarkable advantages, the current generation of code LLMs exhibits notable limitations that impact their practical effectiveness in real-world software engineering scenarios. These models frequently produce code that is inefficient or suboptimal in runtime performance, demonstrate opaque reasoning processes, and struggle to adapt effectively to diverse developer contexts and specific requirements. Moreover, …

Design-Led Leadership: A Mixed Methods Study On Understanding How Design Thinking Capabilities Impact Leadership Effectiveness, Tareq Waleed Muhmood

Dissertations and Theses Collection (Open Access)

“Widespread design thinking among organisation leaders is desirable for the creation of a humanly and sustainable future” (R. J. Boland et al., 2008a)

This study investigates the impact of design thinking capabilities on leadership effectiveness through a mixed-methods research design.

While design thinking is widely used in product and service innovation, its application as a leadership development framework remains underexplored.   To address this gap, the study employed both quantitative and qualitative methods, including pre- and post-intervention survey of leaders, their supervisors, and subordinates within an education business in Vietnam (EBV), as well as semi-structured interviews with senior leaders at a …

Teaching Ai For Radiology Applications: A Multisociety-Recommended Syllabus From The Aapm, Acr, Rsna, And Siim, Felipe Kitamura, Timothy Kline, Daniel Warren, Linda Moy, Roxana Daneshjou, Farhad Maleki, Igor Santos, Judy Gichoya, Walter Wiggins, Brian Bialecki, Kevin O'Donnell, Adam E. Flanders, Matt Morgan, Nabile Safdar, Katherine P. Andriole, Raym Geis, Bibb Allen, Keith Dreyer, Matt Lungren, Monica J. Wood, Marc Kohli, Steve Langer, George Shih, Eduardo Farina, Charles E. Kahn, Ingrid Reiser, Maryellen Giger, Christoph Wald, John Mongan, Tessa Cook, Neil Tenenholtz

Department of Radiology Faculty Papers

No abstract available

Teaching Ai For Radiology Applications: A Multisociety-Recommended Syllabus From The Aapm, Acr, Rsna, And Siim, Felipe Kitamura, Timothy Kline, Daniel Warren, Linda Moy, Roxana Daneshjou, Farhad Maleki, Igor Santos, Judy Gichoya, Walter Wiggins, Brian Bialecki, Kevin O'Donnell, Adam E. Flanders, Matt Morgan, Nabile Safdar, Katherine P. Andriole, Raym Geis, Bibb Allen, Keith Dreyer, Matt Lungren, Monica J. Wood, Marc Kohli, Steve Langer, George Shih, Eduardo Farina, Charles E. Kahn, Ingrid Reiser, Maryellen Giger, Christoph Wald, John Mongan, Tessa Cook, Neil Tenenholtz

Department of Radiology Faculty Papers

No abstract available.

What Time Is It? It Is 8 And 1/2 Time: A Rare Case Of Ischemic Stroke Consistent With Eight-And-A-Half Syndrome, Jessica Daza, Marcelo Bedoya-Sommerkamp, Eunbee Cho, Celia Patricia Daza, Francisco Gomez, Fatimah Bello, Jia Lin

School of Medicine Publications

Eight-and-a-half syndrome is a rare neuro-ophthalmic syndrome characterized by conjugate horizontal gaze palsy, ipsilateral internuclear ophthalmoplegia, and ipsilateral facial nerve palsy. It results from a lesion affecting the paramedian pontine reticular formation, the medial longitudinal fasciculus, and the abducens nucleus of the same side, at the level of the lower pons. We present a case of a 49-year-old man with 2-week diplopia and 3-day right-sided facial droop, drooling, and dysarthria. CT angiography of the head and neck revealed atherosclerotic disease, with decreased caliber of the basilar artery at the level of the pons. Brain MRI showed a subacute ischemic lesion …

Morphology-Performance Relationships To Understand Cichlid Neurocranial Evolution In The Context Of Adaptive Radiation, Sarah Pascarella

Theses and Dissertations from DePaul University

Cichlid fishes have undergone multiple adaptive radiations in the rift lakes of East Africa pairing rapid taxonomic and morphological diversification. Lake Malawi’s rock-dwelling cichlids (mbuna) have diversified into hundreds of species that partition their habitat by depth and diet resulting in high morphological and behavioral diversity. We characterized morphological differences and performed behavioral assays among four cichlid genera from Lake Malawi focused on understanding form-function relationships in the neurocranium and oral feeding apparatus. We characterized neurocranial shape using 3D geometric morphometrics across a large taxonomic sample of mbuna cichlids, focusing primarily on the Tropheops species complex. Alongside broad changes in …

Burdens Of Proof In Criminal Procedure, Eve Brensike Primus

Articles

The Supreme Court’s haphazard approach to allocating burdens of proof in criminal procedure has created a system in which constitutional rights can be rendered meaningless simply because defendants are required to prove things they cannot possibly know. Even though allocations of the burden of proof often drive litigation outcomes, the Court has failed to establish clear burden allocation structures for cases arising under the Fourth, Fifth, Sixth, and Fourteenth Amendments, leaving lower courts split about how to allocate the burdens. When the Supreme Court does allocate burdens, it often does so without explanation or consideration of key factors. Recent Supreme …