Digital Commons Network^™

Brain Morphology Mediators Of The Link Between Childhood Trauma And Bipolar Disorder: A Large-Scale International Analysis, Leonardo Tozzi, Maria R Dauvermann, Emma Corley, Andrea Fernandes, Melody J Y Kang, Yanghee Im, Leila Nabulsi, Roberto Goya-Maldonado, Klaus Berger, Marco Hermesdorf, Hilary P Blumberg, Lejla Colic, Tamsyn E Van Rheenen, Elysha Ringin, Susan L Rossell, James A Karantonis, Lisa S Furlong, Tilo Kircher, Frederike Stein, Udo Dannlowski, Dominik Grotegerd, Jair C Soares, Mon-Ju Wu, Giovana B Zunta-Soares, Benson Mwangi, Joaquim Radua, Enric Vilajosana, Eduard Vieta, Melissa J Green, Emilie Olie, Guillaume Clain, Francesco Benedetti, Elisa Melloni, Beatrice Bravi, Delfina Janiri, Daniela Vecchio, Fabrizio Piras, Nerisa Banaj, Gabriele Sani, Gloria Roberts, Janice M Fullerton, Bronwyn J Overs, Philip B Mitchell, Jonathan Savitz, Lakshmi N Yatham, Josselin Houenou, Marion Leboyer, Amanda Rodrigue, David C Glahn, Sophia I Thomopoulos, Neda Jahanshad, Paul M Thompson, Ole A Andreassen, Christopher R K Ching, Dara M Cannon, Yann Quidé, Enigma Bipolar Disorder Working Group

Faculty, Staff and Student Publications

Childhood trauma is a risk factor for bipolar disorder, but the biological mechanisms of this association remain incompletely defined. Gray matter differences observed after trauma exposure overlap with those reported in bipolar disorder, suggesting that the association between childhood trauma and bipolar disorder might be mediated through brain morphology.

Our goal was to determine whether cortical thickness, cortical surface or subcortical volume mediate the association between childhood trauma and bipolar disorder. We leveraged a large multi-site dataset from the ENIGMA Bipolar Disorder Working Group, comprising of 1,031 participants with bipolar disorder and 2,221 controls from 19 international cohorts. To identify …

Molecular Fluctuations Inhibit Intermittency In Compressible Turbulence, Ishan Srivastava, Andrew Nonaka, Weiqun Zhang, Alejandro Luis Garcia, John B. Bell

Faculty Research, Scholarly, and Creative Activity

In the standard picture of fully developed turbulence, highly intermittent hydrodynamic fields are nonlinearly coupled across scales, where local energy cascades from large scales into dissipative vortices and large density gradients. Microscopically, however, constituent fluid molecules are in constant thermal (Brownian) motion, but the role of molecular fluctuations in large-scale turbulence is largely unknown, and with rare exceptions, it has historically been considered irrelevant at scales larger than the molecular mean free path. Recent theoretical and computational investigations have shown that molecular fluctuations can impact energy cascade at Kolmogorov length scales. Here, we show that molecular fluctuations not only modify …

Timing And Mode Of Death Following Treatment Of Neonatal Symptomatic Tetralogy Of Fallot, Sara M Trucco, Yun Zhang, Andrew C Glatz, Michael L O'Byrne, Christopher J Petit, Athar M Qureshi, Jeffrey D Zampi, Shabana Shahanavaz, George T Nicholson, Allen Ligon, Jennifer C Romano, Shiraz A Maskatia, Jeffery J Meadows, Christopher Mascio, Jay Patel, Kathryn Stack, Asaad G Beshish, Mark Law, Sarosh P Batlivala, Jeannette Wong-Siegel, Kristal Hock, Sarah Speed, Hala Khan, Disha Goel, Courtney Mccracken, Bryan H Goldstein

Faculty, Staff and Students Publications

Background: Neonates with tetralogy of Fallot and symptomatic cyanosis (sTOF) require early intervention, using a staged or primary repair strategy. Postprocedural mortality risk within this group is considerable. The mode of death and associated factors have been inadequately defined in early childhood mortality following treatment of sTOF. This study aims to describe the timing, cause, and associated risk factors of postprocedural death in infants with sTOF.

Methods: Neonates with sTOF who had an initial intervention from 2005 to 2017 at 9 centers of the Congenital Cardiac Research Collaborative were reviewed. Among nonsurvivors, details regarding timing, cause of death, and last …

Optimising Drowning Prevention Counselling Through A Physician Maintenance Of Certification (Moc) Quality Improvement (Qi) Initiative, Tracy E Mccallin, Anthony R Arredondo, Elizabeth A Camp, Shabana Yusuf

Faculty, Staff and Students Publications

Drowning is the leading cause of death in children 1–4 years old in the USA. Paediatricians play an important role in giving anticipatory guidance on drowning prevention. This quality improvement initiative aimed to increase the rate of drowning prevention counselling with provision of educational materials to caregivers of children aged 0–10 years during clinical encounters in an outpatient setting.

We refined a previously published Texas state educational programme that included evidence-based counselling strategies across three Plan Do Study Act (PDSA) cycles, with the addition of preintervention baseline counselling phase during expansion of the programme nationally to 17 and 21 states …

Global Trends And Forecast Of Cardiovascular Diseases, Cancer, And Shared Risk Factors: Insights From The Gbd 2021, Chieh Y Koo, Bryan Chong, Jayanth Jayabaskaran, Srinithy Nagarajan, Silingga M Jauhari, Yiming Chen, Li L Tan, Anurag Mehta, Muhammad S Khan, Mark Muthiah, Derek Hausenloy, A M Richards, Dennis T Ko, Christian D Mallen, Eric A Secemsky, Mark Y Chan, Paaladinesh Thavendiranathan, Nicholas W S Chew, Mamas A Mamas

Faculty, Staff and Students Publications

Background: Cardiovascular disease (CVD) and cancer share multiple risk factors and are the leading causes of morbidity and death worldwide. This study aims to examine historical and projected trends of the combined CVD-cancer global estimates and their shared risk factors.

Methods: Death and disability-adjusted life years (DALYs) associated with CVDs, cancers, and their risk factors were obtained from the GBD (Global Burden of Disease) 2021 study. Historical estimates from 1990 to 2021 and forecast data from 2025 to 2050 were examined across age groups, regions, sociodemographic index, and sex.

Results: In 2021, CVD-cancer resulted in age-standardized DALY rates of 8009 …

Improving Coral Restoration Outcomes Through Novel Molecular Applications, Matthew H. Gamache

USF Tampa Graduate Theses and Dissertations

Coral reef ecosystems are declining globally from numerous stressors, including localized pollution, disease, and marine heatwaves induced by climate change. To preserve these ecosystems, it is critical to identify corals that can withstand stressors—primarily future marine heatwaves—and prioritize them for coral restoration efforts until these stressors are mitigated. Coral responses to thermal stress can be influenced by several partners, including mutualistic microalgae and a vast prokaryotic community. Here, I use advanced molecular techniques to examine which partners (coral host, algal symbiont, and microbial communities) are associated with coral health, how they contribute to holobiont physiology, and their potential to increase …

A Generative Ai Teaching Assistant For Personalized Learning In Medical Education, Thomas Thesen, Soo Hwan Park

Dartmouth Scholarship

Medical education faces a scalability crisis, where rising class sizes strain individualized instruction, while students increasingly adopt unvalidated Generative AI (GenAI) tools for individualized learning support. This study investigated how medical students integrate constrained GenAI systems into their self-directed learning practices using Retrieval-Augmented Generation (RAG), which limits large language model responses to instructor-curated materials, thereby reducing hallucinations while maintaining pedagogical utility. We deployed a RAG-based teaching assistant in a medical school basic science course across two consecutive cohorts, examining usage patterns, conversation content, and student feedback to understand adoption and learning behaviors. Students demonstrated strategic, context-dependent usage, with engagement intensifying …

Timing And Mode Of Death Following Treatment Of Neonatal Symptomatic Tetralogy Of Fallot, Sara M Trucco, Andrew C Glatz, Et Al.

2020-Current year OA Pubs

BACKGROUND: Neonates with tetralogy of Fallot and symptomatic cyanosis (sTOF) require early intervention, using a staged or primary repair strategy. Postprocedural mortality risk within this group is considerable. The mode of death and associated factors have been inadequately defined in early childhood mortality following treatment of sTOF. This study aims to describe the timing, cause, and associated risk factors of postprocedural death in infants with sTOF.

METHODS: Neonates with sTOF who had an initial intervention from 2005 to 2017 at 9 centers of the Congenital Cardiac Research Collaborative were reviewed. Among nonsurvivors, details regarding timing, cause of death, and last …

Lrp8 Is An Entry Receptor For Tick-Borne Encephalitis Viruses, Pengfei Li, Sean Hui, Zhenlu Chong, Michael N Nguyen, Stefanie P Muraro, Hana Janova, Hongming Ma, Shiqi Cao, Tomasz Kaszuba, Brian Imbiakha, Sathvik Palakurty, David A Price, Gaya K Amarasinghe, Daisy W Leung, Daved H Fremont, Michael S Diamond, Et Al.

2020-Current year OA Pubs

Orthoflaviviruses are a genus of arthropod-transmitted RNA viruses that infect humans and other vertebrate animals on a global scale, resulting in extensive morbidity and mortality. Among the orthoflaviviruses, tick-borne encephalitis viruses (TBEV) are an antigenic group that causes severe neurological disease in humans. However, the entry receptors for TBEV, which contribute to cell and tissue tropism, remain largely unknown. Because recent studies identified members of the low-density lipoprotein receptor (LDLR) family as possible receptors for some orthoflaviviruses and distantly related alphaviruses, we performed a targeted screen in transgenic cells expressing different LDLR members and identified LRP8 (also called ApoER2) as …

Semaglutide And Diabetic Retinopathy: An Ohdsi Network Study, Cindy Xinji Cai, Linying Zhang, Ruochong Fan, Adam Wilcox, Albert Lai, Et Al.

2020-Current year OA Pubs

INTRODUCTION: Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA) used to treat type 2 diabetes mellitus (T2D), has potential associations with higher rates of diabetic retinopathy (DR) complications including proliferative DR (PDR) and diabetic macular edema (DME). The purpose of this study was to determine whether an association exists between semaglutide and PDR and treatment-requiring DR/DME.

RESEARCH DESIGN AND METHODS: This was a retrospective cohort study of 14 databases (six administrative claims and eight electronic health records) in the Observational Health Data Sciences and Informatics Evidence Network. Adults with T2D on semaglutide, other GLP-1RA (dulaglutide, exenatide), or non-GLP-1RA medications (empagliflozin, sitagliptin, …

Telehealth Education Leveraging Electronic Transitions Of Care For Copd Patients (Tele-Toc): A Study Protocol For A Type Ii Hybrid Effectiveness-Implementation Randomised, Pragmatic Clinical Trial Of A Pharmacist-Led Intervention, Deepa Ramadurai, Cathryn T Lee, Leah Traeger, Geoff Pucci, Andrea Jackson-Sagredo, Sachin Shah, Joanna Abraham, Vineet M Arora, Valerie G Press

2020-Current year OA Pubs

INTRODUCTION: Transitions of care (TOC) between hospital, ambulatory and home settings for high-risk adults with chronic diseases are complex, costly and often result in poor health outcomes. Suboptimal care transitions lead to medication errors, non-adherence, decreased self-management skills and inadequate follow-up, all of which contribute to readmissions or emergency department visits. The Transitional Care Model aims to address these challenges through patient-centred, in-home interventions. We propose to implement and evaluate TELE-TOC: Telehealth Education Leveraging Electronic Transitions Of Care for Chronic Obstructive Pulmonary Disease (COPD) patients. This study will evaluate the added value of a virtual, pharmacy-based intervention integrated into an …

Fraggin’ The Superhero Genre: Parody And Carnival In Dc’S Lobo, Ryan L. Johnson

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

This essay examines the DC anti-hero Lobo as an ideal example of the constructive, creative power of parody and Bakhtinian carnival. Unlike Bakhtin’s assertion that carnival since the Renaissance has lost its spirit of play and become purely destructive, Lobo uses grotesque violence to create just as much as he destroys social norms. Ultimately, the mini-series under consideration provide a valuable tool for students to understand carnival, parody, and its power as criticism.

Stolen, Lost, And Replaced: Testimonios Regarding Chicana Responsibilities To The Spanish Language, Fawn-Amber Montoya, Ashley Martinez

International Journal on Responsibility

Using testimonio, the authors address how the Spanish language represents a component of Chicana identity. They illustrate how geography, history, and colonization impact Chicanas’ relationship with the Spanish language. Using testimonio allows the writers to explore the Spanish language in the United States through their personal experiences.

Resumen

Usando “testimonio”, las autoras abordan cómo el idioma español representa un componente de la identidad chicana. Ilustran cómo la geografía, la historia y la colonización afectan la relación de las chicanas con el idioma español. El uso de “testimonio” permite a las autoras explorar el idioma español en los Estados Unidos a …

What’S On Our Shores? A Study Of Marine Debris And Cigarette Litter Concentrations In Daytona Beach, Fl., Noelle-Marie T. Steele, Lisa Glover, Parisa Embrahimbabaie Dr, Kelly Sanantonio, Hyun Jung Cho Dr

Sustainability Conference

Marine debris, defined by the National Oceanic & Atmospheric Administration (NOAA), is any persistent, artificial, or processed solid material discarded into the marine and coastal environment. This growing global issue poses significant threats to marine life, coastal ecosystems, and human health. The present study aimed to assess the amount and types of marine debris, with an emphasis on cigarette butts, at two public beaches in Daytona Beach, Florida, a highly urbanized and heavily visited tourist location. Field surveys were conducted from April through July 2025 at the oceanfront beaches of Sunsplash Park and Main Street Pier using transect-based NOAA Marine …

Full Issue, Volume 4, Press Humboldt

CSU Journal of Sustainability and Climate Change

Volume 4, 2025

Comparative Analysis Of Probiotic Viability In Alcoholic And Non-Alcoholic Kombucha, Isabella N. Cerrone, Brooke Pirkle, Danielle Williamson, Gianna Vendrell, Chloe Kraft

Humboldt Journal of Microbiology

Kombucha is a fermented tea beverage valued for its probiotic and antimicrobial properties that arise from complex molecular interactions between yeast, acetic acid bacteria (AAB), lactic acid bacteria (LAB), and metabolic byproducts of fermentation. With the rising demand for non-alcoholic versions of traditionally alcoholic kombucha beverages, ethanol reduction methods have become common, though their impact on probiotic viability and antimicrobial properties remains poorly understood. This study investigates the effects of ethanol removal on kombucha’s functional properties, including probiotic survival, antimicrobial activity, and organic acid composition (pH). We compared alcoholic and non-alcoholic versions of JuneShine kombucha across five flavors. Probiotic viability …

Growth Trends In Abundance And Diversity Of Synthetic Microbial Communities Over Varying Thermal Conditions, Mariska M. Kessler, Jocelyn Wolfinger, Destiny S. Alcaraz

Humboldt Journal of Microbiology

Microorganisms create various communities that act as the foundation of ecosystems. Abiotic factors such as temperature variability and environmental fluctuations are known to produce shifts in the abundance and diversity of microbial communities, but our current understanding is limited. In this study, we aimed to address this gap by observing abundance and diversity growth patterns under different temperature conditions within individual species and communities. Samples of 4 isolates and 4 artificial communities were grown at constant and fluctuating temperatures. Results found that the isolate samples had the highest abundance under constant high temperatures, whereas the community samples had the highest …

Giant Cell Arteritis After Mrna Covid Vaccines: Concerning Or A False Alarm?-A Retrospective Cohort Study, Syed M. F. Zabiullah, Rutwik Pradeep Sharma, Roshan Subedi, Viqarunnisa Faaiza Zahid, Yasir Loai, Sarathlal Mannumbethlal, Aatifa Aatifa

Advances in Clinical Medical Research and Healthcare Delivery

Background: The coronavirus disease (COVID-19) pandemic led to the first large-scale rapid deployment of novel messenger RNA (mRNA) vaccines. Although the effectiveness and safety of these vaccines were rigorously studied, post-vaccination adverse events such as giant cell arteritis (GCA) continue to be reported. More than two hundred and sixty three cases of new-onset GCA occurring after mRNA vaccine administration are listed in the Vaccine Adverse Events Reporting System as of October 2024. We aimed to explore the incidence of GCA after mRNA vaccines among patients in our health system and study their characteristics and outcomes.

Methods: We conducted a …

Hepatocellular Carcinoma Surveillance In Patients With Cirrhosis, Identifying Gaps In Clinical Practice, Abdullah Orakzai, Muhammad Hammad Sharif, Basil George Verghese, Shiamak Cooper, Venkat Arutla, Purva Shah, Himal Kharel, Aditya Sanjeevi, Aniket-Vijay Rao

Advances in Clinical Medical Research and Healthcare Delivery

Background:Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide, with rising mortality rates in the United States. Early detection of HCC through routine screening significantly improves survival rates in patients with cirrhosis. Current guidelines recommend bi-annual screening using abdominal ultrasound with or without serum AFP levels; however, adherence to these guidelines is suboptimal in clinical practice.

Methods:We conducted a retrospective study of 320 adult patients diagnosed with HCC at our institution between January 1, 2023, and July 31, 2023. Patients aged >22 years were included, and their medical records were reviewed to evaluate routine surveillance …

November 2025, Office Of Sustainability

Office of Sustainability Newsletter

No abstract provided.

2025 November 3 - Faculty Senate Agenda And Minutes, Faculty Senate, East Tennessee State University

Faculty Senate Agendas and Minutes

No abstract provided.

The Role Of A Luxury Brand For The Professional Competitiveness Of Brazilian Business Women, Irene Raguenet Troccoli, Patricia Da Silva Leite, Joyce Gonçalves Altaf

Journal of Marketing and Consumer Behaviour in Emerging Markets

This qualitative article explores the significance of a luxury women’s shirt brand in fostering the professional competitiveness of Brazilian Generation Y women. It does this by identifying the personal values that motivate women to wear these shirts, based on the Means-End Theory. This theory was operationalized using the Soft Laddering technique and complemented by non-participant observation. The result is that these shirts play a role in securing respect – primarily professional, but also personal – from third parties for the wearers, helping them to perceive themselves as successful in their careers. This study is the first to examine the ability …

Electric-Field Tunable Magnetoexcitons In Xenes/Hbn/Tmdc, Xenes/Hbn/Bp, And Xenes/Hbn/Tmtc Heterostructures, Roman Ya. Kezerashvili, Anastasia Spiridonova, Klaus Ziegler

Publications and Research

In this work, we propose novel van der Waals heterostructures composed of Xenes, transition metal dichalcogenides (TMDCs), phosphor ene, and transition metal trichalcogenides (TMTCs), which are separated by insulating hexagonal boron nitride (hBN) layers. We theoreti cally investigate the behavior of Rydberg indirect excitons in Xenes/hBN/TMDC, Xenes/hBN/phosphorene and Xenes/hBN/TMTC heterostructures subjected to parallel external electric and magnetic fields that are oriented perpendicular to the layers. By incorporating both isotropic and anisotropic materials, we demonstrate that excitonic properties can be effectively tuned through the external field strengths and the heterostructure design. Our results show that the exciton reduced mass and the …

Experts’ Validation Of The Fundamental Cybersecurity Competency Index (Fcci) Using A Commercial Cyber Range Through Human-Generative Artificial Intelligence (Genai) Teaming, Dariusz Witko, Yair Levy, Catherine Neubauer, Greg Simco, Laurie P. Dringus, Melissa Carlton

Journal of Cybersecurity Education, Research and Practice

The increasing volume of cyber threats, combined with a critical shortage of skilled professionals and rising burnout among practitioners, highlights the urgent need for innovative solutions in cybersecurity operations. Generative Artificial Intelligence (GenAI) offers promising potential to augment human analysts in cybersecurity, but its integration requires rigorous validation of the fundamental competencies that enable effective collaboration of human-GenAI teams. This research study employed a mixed-methods research project designed to evaluate human-GenAI teams, emphasizing the role of expert consensus in shaping the experimental assessment of the Fundamental Cybersecurity Competency Index (FCCI) in a commercial cyber range. We engaged 20 Subject Matter …

Anthony Viola V. Us Department Of Justice

2025 Decisions

USDC for the Western District of Pennsylvania

The Relationship Between Physical Activity And Cognitive Performance In African American Older Adults, Rio S. Tate

USF Tampa Graduate Theses and Dissertations

The number of older adults in the United States is expected to increase in the years to come. As we age, cognitive performance is noted to decline. African American older adults are more likely than non-Hispanic Whites to experience cognitive impairment and dementia. It is known that physical activity is a modifiable risk factor for dementia. It is not known the extent to which physical activity engagement is related to cognitive performance in African American older adults, and which variables, if any, moderate this association. To answer this question, the authors examined the association between three intensities of physical activity …

Recruitment, Retention, And Attrition Of Special Education Teachers At Title 1 Schools: How Administrators Perceive Their Role, Sherry Jane S.

USF Tampa Graduate Theses and Dissertations

The United States needs more special education teachers. Although this shortage affects many schools nationwide, the effects can be particularly harmful at Title 1 schools. Although there is a large body of literature on teacher attrition and retention, enlarging it focuses on teachers' viewpoints. Through semi-structured interviews, this research examines the perceptions of school administrators at Title 1 schools about their role in the recruitment, attrition, and retention of special education teachers. The context of the research is one large district in central Florida

Crow's Nest, November 3, 2025, Crow's Nest Staff

Crow's Nest

The November 3, 2025 issue of Crow's Nest.

The Experience Of Administrative Burdens In Snap And Medicaid: New Evidence From A Nationally Representative Survey Of Low-Wage Workers, Stephen Roll, Mathieu Despard, Yung Chun

Center for Social Development Research

When functioning correctly, the U.S. social safety net ensures that everyone can reach a basic standard of living, regardless of economic circumstances, and provides financial support to help families who have fallen on hard times due to job losses or other adverse life events. However, the programs often have complex rules around eligibility, documentation requirements, and compliance. Those features and negative experiences with program staff impose psychological costs—collectively referred to as administrative burdens—that can make enrolling and staying in the programs difficult for many families. Drawing upon data from the Workforce Economic Inclusion and Mobility Survey of a nationally …

Quality Improvement Project: Impact Of Educational Intervention On Post-Acute And Long-Term Care Staff's Confidence And Accuracy In Aims Screening For Tardive Dyskinesia, Tana Whitt

Doctor of Nursing Practice Projects

Tardive dyskinesia (TD) is a chronic, often irreversible movement disorder associated with prolonged antipsychotic use. In post-acute and long-term care (PALTC) settings, inconsistent Abnormal Involuntary Movement Scale (AIMS) screening practices and limited clinician education contribute to under recognition and delayed treatment. This Doctor of Nursing Practice (DNP) quality improvement (QI) project evaluated whether an educational intervention impacted clinicians’ knowledge, confidence, and perceived importance of AIMS screening among licensed and unlicensed PALTC staff. Guided by Donabedian’s Model of Quality and Kotter’s 8-Step Change Model, the project used a pre-test/post-test design to measure outcomes before and after completion of the Drug-Induced Movement …