Digital Commons Network^™

Effects Of Maternal Overnutrition And Metabolic Challenge In Adult Life On The Histological Integrity Of The Liver And Intestinal Epithelium In Rabbits, Lucía Carolina Cano, Erika Navarrete, Pedro Medina, Juan Pablo Ochoa-Romo, Georgina Díaz, Rodrigo Montúfar-Chaveznava, Rosa María Vigueras-Villaseñor, Ivette Caldelas

Artículos científicos

Introduction: Maternal overnutrition during critical stages of embryonic development has been implicated as a major determinant of developmental and metabolic disturbances in offspring. Current data concerning how perinatal exposure to high-fat and high-carbohydrate diets, followed by re-exposure in adulthood (metabolic challenge), affects the metabolic regulation and structural integrity of the liver and small intestine, key organs of the gut–liver axis (GLA), are limited. Methods: Female rabbits were fed either a standard diet (SD) or a high-fat and high-carbohydrate diet (HFCD) before mating and during gestation. The offspring on postnatal day 440 were challenged with an HFCD or SD for 30 …

Driving Complex Thinking And Technological Entrepreneurship With Artificial Intelligence: A Mixed Methods Study, Inés Alvarez-Icaza, J. Miranda, A Martínez-Arboleda, P Suarez-Brito, María Soledad Ramírez-Montoya

Artículos científicos

AI technologies offer unique capabilities that enhance collaboration and creativity among students by providing novel insights, generating diverse perspectives, and triggering the development of innovative thinking as a subcompetency of the mega-competency of complex thinking. Regarding entrepreneurial skills development, applying AI-powered tools, such as natural language processing on digital educational platforms, allows students to engage in dynamic ideation processes for entrepreneurial projects with social, technological, and scientific approaches. This article explores the application of artificial intelligence (AI) as a valuable resource for fostering creative idea generation within co-creation strategies for university students. In a mixed-method analysis, we obtained valuable information …

Spike Train Analysis In Rehabilitation Movement Classification Using Deep Learning Approach, Fadilla Atyka Nor Rashid, Marizuana Mat Daud, Nor Surayahani Suriani, Mahidur R. Sarker, Maher G. M. Abdolrasol, Hassan Abdurrahman Shuaibu, Taha Selim Ustun

Artículos científicos

The rapid advancement of sensor technologies has sparked significant interest in intelligent physiotherapy monitoring systems, which hold immense potential for improving assessment quality. Despite this promise, existing sensor technologies for physiotherapy evaluation often need to be expanded in their versatility and robustness. This research introduces an innovative approach using spike train feature extraction to enhance patient progression tracking for physiotherapy assessment. developed a novel approach that reveals distinctive patterns for each physiotherapy exercise by implementing spike trains as the primary feature extraction method. The methodology used three datasets: UI-PRMD, K3Da, and a Self-Collected dataset, which were encoded into spike train …

Leveling The Playing Field? Exploring The Moral Ambiguity Of The Private Attorney General Model, Nathan Heastie

Washington and Lee Law Review Online

Johnson & Johnson’s market cap is twice the GDP of Oklahoma. So, when Oklahoma hauled Johnson & Johnson and other behemoth pharmaceutical companies into state court for their participation in the opioid epidemic, Big Pharma’s resources created a David v. Goliath situation. Against all odds, Oklahoma stood toe-to-toe with Big Pharma and brought home more than $650 million in settlement funds.

Oklahoma’s success would be otherwise impossible without the assistance of three private law firms serving the role of “private attorneys general.” The State signed contingency fee arrangements with the firms, transferring the financial burden of litigation from the State …

Representing The Incommunicado Client: Regulating The Attorney-Client Relationship In A Civil Rights Emergency, Michael Kagan

Washington and Lee Law Review Online

When the government obstructs a detainee’s ability to communicate with attorneys, normal rules governing the formation of attorney-client relationships break down. While some work-arounds exist to allow lawyers to bring such cases to court, they have significant limitations and can create problems of their own. The legal profession and the courts should adopt new rules modeled on emergency medicine to facilitate the filing of urgent civil rights claims for clients who are not in a position to consent. In emergency medicine, physicians can presume client consent for certain narrow and urgent purposes. Certain lawyers, in extreme cases, should be able …

Elucidating The Oxidation Mechanisms In Cr2alb2 Using Density Functional Theory And Thermodynamic Modeling, Ushan Asela Adhikarige

Theses and Dissertations

This thesis investigates the oxidation behavior of Cr2AlB2 surfaces using density functional theory calculations combined with thermodynamic modeling. Our analysis encompassed surface stability assessments, oxygen adsorption studies on various surfaces, and thermodynamic insights into oxidation mechanisms. Surface stability assessments reveal that the (010) surface terminated with an Al layer exhibits the lowest surface energy. Oxygen adsorption studies on the (010), (111), and (021) surfaces demonstrate strong dissociative adsorption with binding energies ranging from -4.72 to -4.22 eV depending on coverage. Thermodynamic analysis shows that elevated temperatures reduce oxidation favorability, while increased oxygen partial pressure enhances it. The study reveals that …

A Climatology Of Northern Plains Tornadoes With Regard To Radar Coverage, Charles Richie Ii

Theses and Dissertations

Tornadoes are among the costliest and deadliest severe weather events in the United States. Doppler weather radar is one of a meteorologist’s most useful tools for early detection of tornadoes. However, there are several notable areas across the Northern Plains (Minnesota, Montana, North Dakota, and South Dakota) where the National Weather Service’s (NWS) radar coverage exceeds 10,000 feet above radar level, leaving an effective “radar gap” where tornado detection becomes increasingly challenging, if not impossible in some cases. Even within these radar gaps, the NWS is still responsible for issuing Tornado Warnings to fulfill their mission of protecting life and …

Gender Differences In Psychological Strengths Among Rural Adolescents, Angela Preston, Jodi Bullard, Rachel Smith, Ashlyn Peppler

Nursing Faculty Publications and Presentations

Purpose: Rural adolescents often lack access to mental health care along with increased rates of depression and suicide completion. While psychological strengths have been associated with positive outcomes globally, little is known regarding the prevalence of these indicators (hope, self‐efficacy, resilience, optimism, and gratitude) among adolescents living in rural Texas. The purpose of this study was to describe how rural adolescents report their psychological strengths and examine the data for potential gender differences.

Design and Methods: A secondary analysis of cross‐sectional data was performed on the RStudio platform using tests of central tendency and inferential statistics. Results: There were 425 …

Pilot Study Of The Barriers To Exercise Adherence And Motivation (Beam) Questionnaire For Adults With Osteoarthritis, Haley Ciara Hughes

Dissertations

Osteoarthritis (OA) is a chronic condition affecting over 33 million adults in the United States (Center for Disease Control and Prevention [CDC], 2024). While exercise is one of the leading, non-pharmacological treatments for OA (Zhang et al., 2008), patients often struggle to meet physical activity guidelines, increasing their risk of lifelong disability, falls, and dependence (Wallis et al., 2013). Researchers in physiotherapy have struggled to identify effective, individualized treatments to improve exercise adherence for patients with OA that maintain long-term effects (Ezzat et al., 2015); an area behavior analysts could offer insight and guidance. Behavior analysts have developed indirect functional …

An Evaluation Of Virtual Reality Modeling To Improve Accuracy Of Physical Education Skills In Teenage Students With Disabilities, Kristen Lee

All Graduate Theses and Dissertations, Fall 2023 to Present

Virtual Reality (VR) technology is becoming more common in schools, especially for teaching and training. In this study, researchers explored how VR can help teenagers with disabilities improve their physical education skills, specifically push-ups, lunges, and jumping jacks. The participants all showed an increase in their skills and reached a high level of accuracy on every skill. The results showed that adding feedback was also necessary for some participants. Additionally, participants enjoyed using the VR equipment and showed high levels of happiness throughout the study. These findings suggested that using VR technology can be an effective way to support teenagers …

Revised Draft Final 2022 Unreclaimed Sites Sampling: Ur-22 Site Evaluation Summary Report, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Assessing Patient Experiences And Priorities In Traumatic Brain Injury Health Care, Temitayo R. Okusanya, Madeline D. Furie, Sergey Tarima, Courtney O. Barry, Terri Deroon-Cassini, Yuka Kobayashi, Michael A. Mccrea, Kathleen S. Williams, Staci A. Young, Lindsay D. Nelson

Biostatistics Faculty Publications

Improving patient experiences and outcomes of traumatic brain injury (TBI) will require understanding patient perspectives of current care systems. Experts have called for building more integrated, patient-centered systems of care to better support patients through stages of TBI recovery. Informed by an earlier qualitative study, we conducted a survey to quantify patient perspectives on discharge and post-discharge experiences across seven hospitals in a single southeastern Wisconsin health system. Eligible participants were English or Spanish speakers and received TBI care between February 2023 and June 2024 at one level I trauma center emergency department (ED) and inpatient unit, two level III …

Quantifying Nuanced Differences In Hand Dexterity Between The Dominant And Nondominant Hands Of Healthy, Right-Handed, Young Adults, Brian J. Conway, Léon Taquet, Timothy F. Boerger, Kaitlin Goetschel, Kate B. Krucoff, Sergey Tarima, Brian D. Schmit, Max O. Krucoff

Biostatistics Faculty Publications

When individuals present with hand injuries, clinicians often use the contralateral hand as an internal control. However, subtle differences in baseline dexterous abilities between the dominant and nondominant hands are poorly understood. To address this gap, here we quantified such differences, measured as independence (individuation) and smoothness of finger movements. A cohort of 47 right-hand-dominant healthy adults (22 males and 25 females) moved each finger independently 10 times, while joint angle data were tracked with a dataglove (CyberGlove III, CyberGlove Systems, San Jose, CA). Each finger’s performance was compared with its counterpart on the opposite hand using Wilcoxon-signed rank tests. …

Bridging The Digital Divide: Enhancing Digital Literacy In Florida's Ged® Education Program, Nicole Howard-Rice

Graduate Student Dissertations, Theses, Capstones, and Portfolios

This dissertation addressed the critical need for mandated digital literacy courses in Florida's General Educational Development (GED®) programs. As digital skills become increasingly essential for success in education, employment, and daily life, GED® recipients often face significant disadvantages due to a lack of digital proficiency. The findings revealed positive results between digital literacy and employability, emphasizing the transformative potential of integrating digital skills training into GED® curricula. The research highlighted the barriers to acquiring digital skills faced by adult learners, including limited access to technology, varying skill levels, and insufficient instructional support. This study advocated for curriculum updates that align …

Development Of Novel Small Molecule Therapeutics For Myotonic Dystrophy, Xhesika Azis

Biological Sciences

Myotonic Dystrophy type 1 (DM1) results from expanded CUG repeat RNA that sequesters MBNL proteins and disrupts alternative splicing. Small molecules that bind toxic repeat RNA and release MBNL proteins represent a promising therapeutic strategy. This thesis examines newly synthesized modified polycyclic compounds (MPCs) engineered to target CUG RNA with enhanced specificity and efficacy. Through Suzuki–Miyaura coupling and benzoquinone-mediated cyclization, MPC03 was synthesized and characterized by NMR and LC–MS.

The biological activity of these compounds was assessed in DM1 patient-derived myotubes and fibroblasts. MPC03 consistently produced dose-dependent rescue of multiple MBNL-regulated exons, restoring splicing patterns toward those observed in healthy …

Empowerment Or Imprisonment? The Line Between Sex Work And Sex Trafficking: A Comparison Of Law Enforcement And Academic Perspectives, Jocelyn Belcastro

Theses/Capstones/Creative Projects

This research explores the line between consensual sex work and sex trafficking to gain a better understanding of the prevalence and pathways through which sex work may transition into sex trafficking. Semi-structured interviews were conducted with law enforcement professionals that work closely with survivors of sex trafficking to examine the pathways from consent to coercion. An interview with a former sex worker, now college professor, was also conducted to examine the lived experience and academic perspective. Both the law enforcement and academic perspectives were analyzed and compared to one another to form a nuanced understanding of the complex issue of …

Comparative Analysis Of The Effects Of Peppermint Oil On Colorectal Cancer Cells And Human Fibroblasts, Allen W. Mccumbers

Theses/Capstones/Creative Projects

This study contrasted the effects of Peppermint Oil on two cell lines, HT29s (colorectal adenocarcinoma cells) and HFFs (Human Foreskin Fibroblasts). Cytotoxic as well as genomic effects were compared between the cell lines. Trypan Blue, Alamar Blue, and qPCR assays were used to study these effects. Both cell lines were treated with a range of Peppermint Oil concentrations, and it was determined that there is a dose-dependent factor associated with cytotoxicity. To confirm results, Alamar and Trypan Blue assays were repeated at 300 and 500 cells/mL respectively. Effects were confirmed, and results were averaged and plotted. Alamar Blue revealed that …

Holistically Analyzing The Initial Athlete-Provider Interaction During Sports Injury Diagnosis, Tyler Baldwin

Theses/Capstones/Creative Projects

Recovering from injury is crucial for an athlete’s health-related quality of life and mental health. A potentially significant moment that could influence an athlete’s mindset towards recovery is the interaction between the provider and athlete during initial diagnosis. To analyze this moment from both perspectives, this study performs a thematic analysis of five semi-structured provider interviews and ten athlete interviews. In this study, all five providers exemplified an understanding of this moment’s significance, expressing awareness of their potential impact on the athlete’s mindset, and emphasizing mutual understanding to ensure streamlined recovery. Meanwhile, all ten of the athletes expressed self-awareness regarding …

Cal Poly Semester Conversion Time Capsule, Maximus La Via, Matthieu Gol, Viki Sarmasi, Tuyetthuc Nguyen

Mechanical Engineering

As Cal Poly transitions from the quarter system to the semester system, aligning itself with the other California universities, the idea has been proposed to commemorate this moment in the history of the university with a time capsule. The time capsule will be on display on the first floor of the library for a few years and later moved into the library’s archive room for permanent storage. 50 years after the completion of the semester conversion project, the time capsule will be opened. This project aims to create a secure and aesthetic device capable of storing and protecting memorabilia from …

Exploratory Diver Geotechnical Equipment (Edge), Angel Villicana, Merrick Zellers, Erik Heuchert, Lucas Heuchert

Mechanical Engineering

The goal of this report is to showcase how our final Core Sampler design and prototype address the needs of Navy Divers. Geotechnical equipment for Navy divers has not been updated since the early to mid-1980s, resulting in imprecise and outdated sampling methods. The primary purpose of this project is to enhance, modernize, and redesign a tool to collect a minimally disturbed core sample of the seabed for geotechnical evaluation. This report presents the full development of our project from concept to verification and final outcomes. It begins with the statement of disclaimer, followed by a four-panel executive summary and …

Clark Memorandum: Fall 2025, J. Reuben Clark Law School, Byu Law School Alumni Association, J. Reuben Clark Law Society

The Clark Memorandum

• Our Constitutional Anchor
• Divine Law
• The Courage of Our Convictions
• Our Call to Action

Intentional Improvement Through 3d Environment Art, Samuel T. Pinnex

Master of Fine Arts in Digital Media Culminating Experience

The idea of self-growth can be exciting—the thought of where one might be in the near or distant future is exhilarating. As an artist, this is even more apparent. On the other side of that coin, the realization that it is all up to you can oftentimes be overwhelming. We all want to improve, and we want our work to improve with us as a showcase of that improvement. Over the past two years, I’ve learned how valuable it is to adopt a “growth mindset”. Once I became comfortable with this idea, the responsibility for my own self-growth no longer …

The Absence Of Something: Addressing Underrepresented Lgbtqia+ Communities In Video Games Through Holistic Character Design Techniques, Lydia Myers

Master of Fine Arts in Digital Media Culminating Experience

This research identifies pain points and gaps in current LGBTQIA+ representation in the video games industry, and showcases the characters that I have created in response to those pain points. Despite the games industry representing LGBTQIA+ individuals often, certain communities under the umbrella are included less often, less accurately, and less respectfully than others. The goal of this research is to identify important considerations for respectfully portraying underrepresented queer communities in video games: specifically transgender, nonbinary, asexual, aromantic, and polyamorous communities, which are especially under-explored. My included characters were created via a holistic approach to character design. Despite my professional …

Methodologies For Generating Passive Income As A Digital Artist, Levi Stone

Master of Fine Arts in Digital Media Culminating Experience

This research provides an in-depth exploration of 3D workflow methodologies for digital merchants, how and why to implement them, and their correlation with passive income earnings. Digestible strategies regarding the development, packaging, marketing, and sale of assets for digital marketplaces are explored at length. Motivated by the state of the digital media industry, this research demonstrates that secondary income is possible through consistent, applied methodologies. Topics include environmental storytelling, the importance of being user friendly, material variance, and much more. The author demonstrates the impact of reframing your approach when designing products with the intention to sell, and explores the …

“For Whom The Bell Tolls”?* Is The Corporate Transparency Act Dead, And If Not, What Is Its Impact On Corporate Governance?, Kellen Ware

UC Law Business Journal

The Corporate Transparency Act (“CTA” or “the Act”) was enacted by Congress in 2021 to combat illicit financial activity through mandated beneficial ownership disclosure. While the current administration has opted not to enforce the CTA’s reporting requirements on domestic entities, the law remains in effect, and its future is uncertain amid ongoing constitutional litigation.

This Note argues that the CTA should be repealed, and state legislatures should refrain from mirroring the Act. The CTA creates undue burdens that threaten effective and efficient corporate governance in small businesses and many non-profits. This Note traces the contentious history of the CTA and …

Alaska Native Disparities In Alaska Jails And Prisons. An Exploratory Study And Descriptive Analysis, Brad A. Myrstol, Cheryl Jones, Rus'sel Sampson, Bri Moffat

AJiC Reports

This report presents an exploratory study of racial disparities in Alaska’s correctional system, combining a review of national research with an analysis of Alaska Department of Corrections (ADOC) booking data.

Exploring The Fusion Of Montessori And Waldorf Pedagogies For Early Literacy Interventions In Children With Autism: Non-Exhaustive Literature Review, Chiquila Q. Dolison

Institute for Disability Studies

No abstract provided.

Validation Of A Scoring System To Predict Difficult Laparoscopic Cholecystectomy In A Tertiary Hospital In Saudi-Arabia: A Retrospective Study, Hazem A. Megahed, Lamiaa Z. Elmoursi, Rakan A. Al-Etebi, Nawaf M. Al-Enazi, Ahmed M. Lashin, Sarah Marie, Ahmed Taki-Eldin

Saudi Medical Journal

ABSTRACT Objectives: To confirm a preoperative scoring system devised by the Modified Randhawa Model. Methods: This retrospective study was performed in the period between October 2017 to October 2023 on every patients hospitalized for elective laparoscopic cholecystectomy in the Surgery Department, National Guard Hospital in Riyadh, Saudi Arabia. A preoperative scoring system, devised using the Modified Randhawa Model, was applied to each patient retrospectively. The preoperative score was compared to the intraoperative degree of difficulty. Results: The history of previous biliary inflammation, the impacted stone, the palpable gall bladder, the more gall bladder wall thickness, the higher body mass index …

Nutritional Knowledge Of The Phenylketonuria Diet Among Healthcare Providers In Saudi Arabia, Nouf A. Alghamdi, Rouba K. Naaman

Saudi Medical Journal

ABSTRACT Objectives: Phenylketonuria (PKU) is associated with detrimental impacts on factors contributing to the etiology of obesity, and metabolism disorders. Therefore, we hypothesized that physicians and dietitians demonstrate a sufficient level of nutritional knowledge of the PKU type diet. The aim of this study is to assess understanding of the PKU diet in relation to current guidelines among dietitians and metabolic physicians in Saudi Arabia. Methods: This study involved 238 participants, primarily Saudi and non-Saudi dietitians and metabolic physicians working in Saudi Arabia, who asked to complete an electronic questionnaire assessing their nutritional knowledge of the PKU diet. The questionnaire …

Identifying Barriers For Community Pharmacies As Vaccines For Children (Vfc) Providers In Rural Alabama: Opportunities For Solutions, Myra Bajwa

Honors Theses

Significant Human papillomavirus (HPV) vaccination disparities exist between rural and urban areas in the US. A primary contributor is low access to preventive care in rural areas. Among the most promising strategies to overcome this is increasing access through offering HPV vaccination in non-traditional, convenient health settings such as pharmacies. In rural areas, community pharmacies are trusted, convenient pillars of the community. In Alabama, community pharmacies are eligible for enrollment in the Vaccines for Children (VFC) Program, a federally-funded program that provides free vaccines to children and adolescents under 18 years old who are uninsured, underinsured, American Indian, or Alaska …