Digital Commons Network^™

Development Of An Untargeted Metabolomics Analytical Protocol For Fecal Samples By Liquid Chromatography–Mass Spectrometry, Tsai-Wei Ting, Chih-Ning Cheng, Chieh-Chang Chen, Ching-Hua Kuo

Journal of Food and Drug Analysis

Gut microbiota has recently gained attention for its role in regulating multiple host pathways and contributing to disease developments. Fecal metabolomics using liquid chromatography—mass spectrometry (LC—MS) offers a promising approach to study gut microbial metabolites; however, it remains technically challenging due to the complex, heterogeneous nature of fecal samples and the lack of standardized protocols. This study aimed to establish a robust and reproducible untargeted fecal metabolomics workflow. We systematically evaluated sample preparation parameters―including sample amount, extraction solvent, numbers of extraction, and sample-to-solvent ratio―and assessed method reproducibility. Additionally, we compared three LC—MS data acquisition workflows using 10 samples from inflammatory …

Selective Sodium-Glucose Cotransporter Two Inhibitor Empagliflozin Ameliorates Diabetic Cardiomyopathy By Activating The Ampk/Tfeb Signaling Pathway., Man-Chen Hsu, Ru-Wen Chang, Mu-Chun Wang, Chia-Hui Chen, Wen-Hua Chen, Tzong-Shyuan Lee, Chih-Hsien Wang

Journal of Food and Drug Analysis

The highly selective SGLT2 inhibitor (SGLT2i) is reported to have beneficial effects on diabetic cardiac hypertrophy; however, the molecular mechanisms underlying the cardioprotection of SGLT2i are not fully understood. In this study, we investigated the impact of the SGLT2 Inhibitor empagliflozin (EMPA) on diabetic hearts and its regulatory mechanisms in high-fat-diet (HFD)- and streptozotocin (STZ)-treated rats. Male rats orally administered HFD/STZ treatment for eight weeks, with or without EMPA (10 mg/kg), were used as our in vivo model. Hematoxylin and eosin (H&E) staining was used for histological examination. Western blot analysis and immunohistochemistry were used to analyze the expression of …

Cordycepin In Cancer Therapy: A Bibliometric Analysis And Review Of Mechanisms, Zhiwei Ouyang, Yufei Zhang, Jianghan Ning, Yayi Tu, Bin He

Journal of Food and Drug Analysis

Cordycepin (3’-deoxyadenosine), a major bioactive component derived from fungi of the genus Cordyceps, has garnered significant attention in recent years for its potent antitumor properties. Drawing on literature indexed in the Web of Science Core Collection from 2004 to 2025, this study employs bibliometric tools―specifically CiteSpace and VOSviewer―to systematically examine developmental trends, research hotspots, and emerging frontiers in the field of cordycepin-related cancer research. The analysis maps a shift in focus from early-stage pharmacological validation to more advanced investigations into molecular mechanisms, with particular emphasis on cell cycle regulation. Keyword burst analysis highlights bursts in terms such as “apoptosis,” “cell …

Research And The Information Landscape, Libby Wheeles, Helena Marvin

Open Educational Resources Collection

This open textbook accompanies the University of Missouri-St. Louis class INTDSC 1010: Research and the Information Landscape. Intended for undergraduates new to academic research, the course covers practical search and evaluation skills as well as a basic introduction to the world of scholarly communication. In Fall 2025, the course’s learning objectives were:

1. Evaluate whether a source is appropriate for college-level research.
2. Navigate library search tools to find relevant results and improve research efficiency.
3. Analyze the goals and limitations of non-library tools in the research landscape.
4. Explain the basic history and current broad practices of scholarly communication.
5. Contribute to a small-scale …

Cv: Rachel Wells (Social Work), Rachel Wells

Social Work Department Faculty Curricula Vitae

No abstract provided.

The Impact Of Social-Emotional Curricula On Criminal Justice Outcomes, Erica L. Chmielewski

Master of Arts in Human Services

Social and emotional learning (SEL) has become a central focus in early childhood education as researchers and practitioners seek effective, developmentally informed strategies to support children's emotional regulation, resilience, and long-term well-being. This capstone project synthesizes empirical and theoretical research published between 2018 and 2023 to examine the effectiveness of SEL interventions, their role in trauma-informed education, and their potential to mitigate long-term risks associated with early adversity. Findings across multiple studies demonstrate that high-quality SEL programs improve emotional functioning, prosocial behavior, and early academic outcomes, with powerful benefits for children in universally delivered, curriculum-based models. The review also highlights …

Rewriting The Monster: Carmilla As Laura's Gothic Double And Subversive Prince Charming In Le Fanu's Queer Gothic Fairy Tale, Annalee Tanner

English Theses

Rewriting the Monster: Carmilla as Laura's Gothic Double and Subversive Prince Charming in Le Fanu's Queer Gothic Fairy Tale

Comparative Pediatric Care Practices In France And The United States, Devin Nemirow

The Crown: Syracuse Honors Research Journal

This paper presents a comparative analysis of pediatric practices in France and the United States, integrating literature review with firsthand clinical experience. Based on an internship in Strasbourg under pediatric specialists, the study examines pediatric roles in private practice and neonatology, highlighting specialties including allergy, rheumatology, and nephrology. Ob-servations from clinical rotations at Sainte-Anne Clinic and Saint Luc Hospital emphasize pa-tient education, parental involvement, and comprehensive preventive care. The paper contrasts the French and American healthcare systems across administration, documentation, vacci-nation policy, and access to care. Notable distinctions include the French Carnet de Santé as a lifelong pediatric health record, …

Socially Interfering Sexual Behaviors In Autistic Adolescents And Treatments As Reported By Behavior Analysts, Steven Pai

Seton Hall University Dissertations and Theses (ETDs)

Caregivers often express concern regarding socially interfering sexual behaviors (SISB) in autistic adolescents, yet recent literature offers limited updates on this topic. Existing survey studies have primarily relied on parent, caregiver, or educator reports, with little focus from the perspective of healthcare professionals. To address this gap, the present study surveyed Board Certified Behavior Analysts (BCBA) about the SISB they encounter, commonly utilized interventions employed, and their perceived effectiveness. Of 120 respondents, 74 qualified BCBAs provided data on behaviors such as socially interfering comments, public masturbation, touching others, and public disrobing. Public arousal, verbal remarks/comments, and sexualized gestures were the …

Puf-Based Digital Money With Propagation-Of-Provenance And Offline Transfers Between Two Parties, Benjamin Bean, Cyrus Minwalla, Eirini Eleni Tsiropoulou, Jim Plusquellic

Electrical and Computer Engineering ETDs

Building on prior concepts of electronic money (eCash), we introduce a digital currency where a physical unclonable function (PUF) engenders devices with the twin properties of being verifiably enrolled as a member of a legitimate set of eCash devices and possessing of a hardware-based root-of-trust. A hardware-obfuscated secure enclave (HOSE) is proposed as a means of enabling a PUF-based propagation-of-provenance (POP) mechanism, which allows eCash tokens (eCt) to be securely signed and validated by recipients without incurring any third party dependencies at transfer time. The POP scheme establishes a chain of custody starting with token creation, extending through multiple bilateral …

Baymont Franchise Systems Inc V. Bernstein Comany Llc

2025 Decisions

USDC for the District of New Jersey

Francois Beavogui V. Attorney General United States Of America

2025 Decisions

Agency

Characterizing Temperature-Dependent Properties Of Fat For Improving High Intensity Focused Ultrasound Simulations, Brian Easthope

Theses and Dissertations

High-intensity focused ultrasound (HIFU) is a non-invasive therapeutic technique that relies on the precise delivery of acoustic energy to ablate diseased tissue. The presence of subcutaneous fat can significantly alter focal accuracy and treatment efficiency due to its distinct thermal and acoustic behavior. This study characterized the temperature-dependent thermal conductivity, thermal diffusivity, specific heat capacity, acoustic attenuation, and acoustic velocity of human subcutaneous fat to improve pretreatment modeling for HIFU therapies. Measurements were performed using a dual needle probe for thermal conductivity and diffusivity, differential scanning calorimetry for specific heat capacity, radiation force balance for attenuation, and through-transmission methods for …

Game-Theoretically Optimal Strategies In Baseball, William Michael Melville

Theses and Dissertations

Baseball players and their managers make numerous decisions that can have a significant effect on the result of the game. The effectiveness of their decision-making strategies depend on the strategies played by their opponents. For example, throwing a first-pitch fastball down the middle is a good strategy against a hitter who always takes the first pitch, but it is a risky strategy against a hitter who likes to swing at the first pitch and who is good at hitting fastballs. Additionally, any payoff a player receives from playing a strategy comes at the expense of their opponent. A batter cannot …

Play-Based Assessment Of The Cardinal Principle, Allyssa Sonnefeld Leavitt

Theses and Dissertations

Gelman and Gallistel (1986) determined five counting principles that are essential for successful counting, including the cardinal principle where children understand that the last number counted represents the quantity of a set of objects. The traditional How many? task and the Give-n task are the most common tasks that have been used to assess whether children understand the cardinal principle. However, many researchers claim that these tasks either overestimate or underestimate children's understanding of the cardinal principle. Some researchers (Baroody & Pellegrino, 2023) suggest that embedding the traditional How many? task in a game may improve its validity. In this …

Full Issue - The Crown, Vol. 2, The Crown

The Crown: Syracuse Honors Research Journal

No abstract provided.

Rapid Detection Of Aflatoxin B 1 Contamination Levels In Peanuts Based On Dual-Band Hyperspectral Imaging And Machine Learning, Lu Ren, Shuyue Shen, Wanrong Shi, Chuang Rui, Maofeng Dong, Tingting Li

Journal of Food Science and Biotechnology

[Objective ] This study aims to achieve rapid detection of AFB 1 contamination levels in peanuts through dual-band hyperspectral imaging and machine learning.[Method ] A peanut AFB 1 contamination level warning model was constructed via a dual-band hyperspectral imaging system consisting of visible near-infrared spectroscopy at 400~1 000 nm and short-wave near-infrared spectroscopy at 900~1 700 nm,combined with machine learning.Peanut samples with four contamination levels were collected,in which the mass fraction of AFB 1 was determined by ultra-high performance liquid chromatography-tandem mass spectrometry.The effects of four pretreatment methods [first derivative,second derivative,multiplicative scatter correction,and standard normal variate (SNV )],two characteristic wavelength …

Enhancing Exercise Engagement And Gait In Parkinson Disease: Participation Factors, Novel Approaches, And The Role Of Rhythmic Auditory Cueing, Allison Haussler

WUSM Theses and Dissertations – All Programs

Parkinson disease (PD) is the second most common neurodegenerative disease, characterized by gait and balance impairments that reduce independence and diminish quality of life. Exercise and other rehabilitation strategies, such as rhythmic auditory cueing, are well-researched methods to address motor impairments. However, despite the strong body of research supporting these approaches, many individuals with PD remain sedentary and do not meet current exercise recommendations. This highlights a critical gap between evidence and real-world behavior.

While prior research identified general motivators and barriers to exercise in people with PD, emerging exercise modalities and the growing diversity of community-based programs emphasize the …

The Effect Of Pterygium On Corneal Biomechanical Properties Using Corvis St, Tararat Hoopholerb, Kosol Kampitak, Supinda Leeamornsiri, Suntaree Thitiwichienlert, Promporn Patarajierapun, Soyci Tiantanyatip

Asian Medical Journal and Alternative Medicine

Introduction: Pterygium is a growth of fibrovascular tissue that originates from the conjunctiva and extends onto the cornea. It can destroy the Bowman’s membrane layer and superficial stroma of the cornea. Therefore, pterygium may affect corneal biomechanical properties.

Objectives: To compare corneal biomechanical parameters using Corvis ST between eyes with and without pterygium in the same patient.

Methods: A prospective study was conducted on 27 participants (mean age 59.67 ± 12.06 years) with unilateral primary pterygium. Each subject underwent ocular examinations, and pterygium size was measured. Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany) was used to measure corneal biomechanical properties. …

Full Issue (52.2, Fall 2025)

New England Classical Journal

No abstract provided.

First_Page Settings Order Article Reprints Open Accessarticle Quantitative Detection Of Salmonella Typhimurium In Ground Chicken Using A Surface Plasmon Resonance (Spr) Biosensor, Sandhya Thapa, Fur-Chi Chen

Food and Animal Sciences Faculty Research

Regulatory agencies worldwide have implemented stringent measures to monitor and reduce Salmonella contamination in poultry products. Rapid quantitative detection methods enable producers to identify contamination early, implement corrective actions, and enhance food safety. This study aimed to develop and optimize a surface plasmon resonance (SPR) biosensor for the quantitative detection of Salmonella Typhimurium in ground chicken. The sensor surface was functionalized with a well-characterized monoclonal antibody specific to Salmonella flagellin, and an SPR workflow was established for quantitative analysis. Ground chicken samples were inoculated with four S. Typhimurium strains at contamination levels ranging from −0.5 to 3.5 Log CFU/g and …

Brief Of Agudath Israel Of America, The Jewish Coalition For Religious Liberty, The National Council Of Young Israel, And The Jewish Community Council Of Sullivan County As Amici Curiae In Support Of Appellants, John A. Meiser, Meredith Holland Kessler

Court Briefs

No. 25-2191
Lost Lake Holdings, LLC v. Town of Forestburgh

On Appeal from the United States District Court for the Southern District of New York, No. 22-cv-10656-VB (Hon. Vincent L. Briccetti)

From the Summary of the Argument

As the district court seemed to recognize early on, JA-1506, the Town of Forestburgh is not going to allow Appellants to build a residential community for Hasidic Jews. Once the developers purchased a shovel-ready property for that purpose, the Town—in the words of one prominent resident and former member of the Comprehensive Plan Review Committee—“circle[d] the wagons.” JA-1570. That former committee member (along …

Advancing Cybersecurity Practice: Explainable Machine Learning For Network Intrusion Detection, Adam Grabowski, Shengjie Xu

Journal of Cybersecurity Education, Research and Practice

This research investigates explainable artificial intelligence (XAI) integration within machine learning (ML)-based intrusion detection systems (IDS), focusing on distinguishing malicious from benign network activities. We employed Random Forest and XGBoost models evaluated on widely recognized datasets, including NSL-KDD and UNSW-NB15, using both binary and multi-class classification tasks. The objective was to enhance cybersecurity operations through improved model transparency and interpretability. By integrating SHAP (SHapley Additive exPlanations) and LIME (Local Interpretable Model-Agnostic Explanations), the study offers comprehensive global and local insights into model decision-making processes. Results demonstrate SHAP's effectiveness in providing a broad, dataset-wide understanding of feature interactions and importance, while …

The Rhetoric Of Imperial Felicitas As A Political Tool In Late Antiquity, Martin Shedd

New England Classical Journal

This article surveys the rhetoric of imperial felicitas (good luck) in Latin literature of the fourth and early fifth centuries in response to Erik Wistrand’s monograph Felicitas Imperatoria (1987). By including not only the emperor’s fortunes, but also the fortunes of the political community directly attributed to his presence or actions in its definition, it presents a more complete analysis of relevant political rhetoric. It demonstrates that the tropes of panegyric were manipulated by petitioners to facilitate political action. Finally, it concludes that the author of Historia Augusta intentionally subverts these tropes to envision a different political system for Rome.

Analyzing Intellectual Alternatives To Student Academic Output ``A Specialized Study Of Academic Design Ideas And Alternatives'', Riyam Rajab Fanjan, Armin Sarkis Khosrof

Journal of King Abdulaziz University: Engineering Sciences

The design idea is the foundation on which the architectural design process. It is the basis for creating a distinguished architectural product that reflects the designer's thoughts, orientations, and way of thinking, whether within the black box or the glass box. Generating and selecting alternatives is one of the most important stages, followed by translating the alternative formally and functionally according to the design methodology followed by the designer and according to the design specifications represented by the type of project and its contextual constraints. In the context of architectural work, the research focuses on defining the design idea, the …

Perceptions Of Inclusion In Disability Communication With Plithogenic Fuzzy Soft Sets, Sonia Guerra Iglesias, Andrea Eugenia Pacheco Lemus, Vallardo Villegas-Ricauter, Lorena Del Carmen Bodero Arizaga, Luis Enrique Silva Adriano

Neutrosophic Sets and Systems

This article explores how scientific communication with disability can foster social inclusion through an awareness of the challenge of conveying ambiguous perceptions across fields. This is a timely topic because inclusive communication facilitates equity and subsequent participation in academic and socio-cultural settings by persons with disabilities; however, the existing body of literature does not take an approach that represents an intrinsic indeterminacy of human perceptions. Absent this intrinsic human quality, research results oversimplify abilities and failures to include persons with disabilities. My approach fulfills this gap by using plitogenic fuzzy soft sets, which is a more generalized mathematical construct to …

Cervical Cancer Screening In Women Over 65 Years Of Age, Tamela Fonseca

General Submissions: Clinical Settings Materials

The study aimed to assess cervical cancer screening practices among at-risk women aged over 65 years, describe adherence to nationally recommended cervical cancer screening guidelines for this same patient group, and provide preliminary insights into adherence among primary care providers (PCPs) and gynecologists.

Study Of Victimization And Perception Of Insecurity In Ecuador: Application Of Hybrid Models With Logistic Regression, Machine Learning, And Neutrosophy, Lorenzo Cevallos-Torres, Mauro M. F. Mediano

Neutrosophic Sets and Systems

Given the victim's rising profile in contemporary victimology and criminology, this study examines victimization and the impact of perceived insecurity, paying particular attention to the situation in Ecuador, where reports of crime and violence in urban areas are on the rise. The overarching goal is to create a reliable model for victimization risk assessment that may also serve as an analytical tool for public policymaking and preventative efforts. One step is to build a classic logistic regression model that takes into account variables like age, sex, education level, occupational category, and level of physical activity. The goal is to understand …

Information Management / Bim Adoption Plan, Robert Moore

Tools

This adoption plan translates the Information Management and BIM adoption strategy into a clear, actionable programme of work. It sets out the specific activities, responsibilities, and sequencing required to build capability across people, processes, and technology, supporting consistent implementation in line with ISO 19650 and organisational objectives. The plan enables progress to be managed, monitored, and reviewed over time, ensuring adoption is proportionate, achievable, and aligned with project and business needs. Overall, it provides a practical mechanism for moving from intent to delivery, embedding Information Management and BIM as standard practice within the organisation.

Uniclass Irish Bim Mandate Guide, Robert Moore

Tools

This guidance document provides practical direction on implementing Uniclass within Irish public sector projects to support the Capital Works Management Framework (CWMF) BIM mandate. It explains how Uniclass, used alongside ISO 19650, IFC, and ICMS, enables consistent classification of information across the asset lifecycle, supporting the creation of a reliable golden thread of data from design through to operation. The document sets out how Uniclass works in practice, clarifying roles and responsibilities, common challenges, and mitigation measures, and includes a worked examples to support consistent application. Overall, the guide positions Uniclass as a key enabler of structured information management, improved …