Digital Commons Network^™

A Mass Cytometry-Based Blood Cell Phenotyping Workflow Enabling Inclusion Of Resource-Limited And Rural Sites In Immune System Studies, Natalie J. Smith, Michael Cohen, Lauren Tracey, Julie Alipaz, Christina Loh, David King, Neha Pulyani, Rebecca Auzins, Elin Gray, Sandra Taylor, Rajat Rai, Steven Kao, Barbara Fazekas De St Groth, Helen M. Mcguire

Research outputs 2022 to 2026

Insight into disease detection and treatment through comprehensive immune phenotyping relies on the generation of high-quality data. However, the execution of robust immune monitoring in clinical trials by flow cytometry is complex due to logistical challenges in sample preparation and reagent stability. These challenges are exacerbated when considering remote and rural communities in Australia, which are burdened by both an increased prevalence and a worse prognosis of many chronic and infectious pathologies. This is not unique to the Australian context as globally remote and rural communities are underrepresented in biomedical research studies, contributing to persistent health inequities. To address these …

The Value Of Saltbush Revegetation For Biodiversity In A Highly Fragmented Landscape, Robert A. Davis, Michael D. Craig, Tim S. Doherty, Jonathan D. Majer, Eddie J.B. Van Etten

Research outputs 2022 to 2026

Secondary salinization is a significant global issue affecting up to 1 billion hectares of land, impacting biodiversity and particularly vegetation. One form of revegetation that can provide a return to landholders is saltbush (Atriplex spp.), which provides forage for a wide range of livestock. The effectiveness of saltbush plantings in providing useful habitat for fauna in agricultural landscapes suffering from secondary salinity is poorly understood. We aimed to address this knowledge gap by surveying bird, ant, and spider communities, and quantifying vegetation structure and floristic composition in saltbush and native woodlands in agricultural landscapes affected by secondary salinization in Western …

S-Methyl Cysteine Sulfoxide: Its Effects On Cardiometabolic Outcomes In High-Fat Fed C57bl/6 Mice And Relevance To Human Health, Caroline R. Hill, Balmer, Hayley Abbiss, Jonathan M. Hodgson, Joshua R. Lewis, Armaghan Shafaei, Lauren C. Blekkenhorst

Research outputs 2022 to 2026

S-Methyl cysteine sulfoxide (SMCSO) is an organosulfur compound with demonstrated hypocholesterolemic, anti-diabetic, and antioxidant benefits in rodents. However, the doses used have limited translatability for humans. We explored whether SMCSO could blunt development of diet-induced metabolic syndrome features in mice using doses that are potentially more translatable and achievable in humans. Male mice (C57BL/6; n = 54) were randomly assigned into one of five groups: [1] normal-diet; [2] high-fat-diet; or high-fat-diet with [3] 60 mg kg⁻¹, [4] 170 mg kg⁻¹, or [5] 350 mg per kg per body weight (BW) of SMCSO, respectively. Doses were administered …

The Associations Between Sleep Environment Factors And Sleep Health In Individuals Living With Neurological Conditions, Mitchell Turner, Laws, Madeline Griffiths, Travis Cruickshank

Research outputs 2022 to 2026

Objectives: To explore associations between air temperature and light in the sleeping environment and sleep health in individuals with neurological conditions. Methods: The sleep health of 46 individuals with neurological conditions (mean age 51.37 ± 14.24 years; 20 males, 26 females) was measured using the Sleep Health Index (SHI). Air temperature and light data were captured across seven days using a light/temperature data logger positioned next to the participant’s bed. Data recorded during the participants’ sleeping periods (determined using a sleep diary) were analyzed. Linear regression models were used to assess the associations between air temperature and light and sleep …

The First Systematic Review Of Treatment Characteristics And Recidivism Outcomes For Indigenous People Who Have Sexually Offended, James L. Finney, Natalie Gately, Suzanne Rock, Braden Hill

Research outputs 2022 to 2026

It is of great importance that research investigates the impact of sexual offender treatment programmes given the damage caused by sexual offences to victims and society more broadly. However, psycho-criminological literature has focused on reporting post-treatment recidivism outcomes for people who have sexually offended homogeneously and has not investigated the unique experiences of Indigenous people. Therefore, we systematically collated and critically appraised studies reporting recidivism outcomes for Indigenous people who have received treatment for sexual offences. Fourteen studies were identified utilising a sample of 5,635 individuals (30.7% Indigenous or First Nations). Recidivism was lower for Indigenous and First Nations people …

It's The Most Diverse Job I’Ve Ever Had: What Do Registered Nurses Working In Australian Schools Do?, Anita Moyes

Research outputs 2022 to 2026

Although nurses have been working in Australian schools for many decades, research has focused primarily on narrow aspects of clinical practice or service delivery in specific regions. The aim of this study was to identify the domains of practice registered nurses report in a typical working day in Australian schools, using interview data from a national sample. Forty-five nurses working in government and nongovernment schools in every state and territory of Australia participated. Interviews were analyzed using inductive content analysis ( Elo & Kyngas, 2008). Six distinct domains of practice characterized nursing work in Australian schools: (i) responding to diverse …

Making Room For ‘Feelings’: What's At Stake For The Theory Of Practice Architectures?, George Variyan, Brad Gobby

Research outputs 2022 to 2026

This paper responds to Thelin, K. [2024. What about feelings? Elaboration on and consideration of the theoretical construct of emotions in practice and practice architectures. International Journal of Leadership in Education, 1–14] intriguing proposal that the theory of practice architectures (hereafter TPA) would benefit from an augmentation to its oft-repeated analytical mantra of ‘sayings, doings and relatings’ by adding the notion of feelings. Thelin's work is motivated by the increasing realisation amongst adherents that TPA has thus far been relatively silent on how emotions mediate practice. As such, there are ongoing efforts to think through the place of emotions in …

Nurses' Perceptions Of Their Non-Technical Skills In Recognising And Responding To Clinical Deterioration In Hospital Settings: A Systematic Review, Darlene Archer, Amineh Rashidi, Rajbeer Kaur, Allison Roderick, Olivia Gallagher

Research outputs 2022 to 2026

Aim: To understand nurses' perceptions of non-technical skills in recognising and responding to clinical deterioration in hospital settings.

Design: A mixed methods systematic review was undertaken, guided by the Joanna Briggs Institute Manual for Evidence Synthesis.

Methods: A systematic search of the primary research literature published between 2012 and October 2025 was undertaken. A convergent integrated approach to synthesis, without meta-analysis, was undertaken.

Data Sources: The MEDLINE, CINAHL, Scopus, PsychInfo and Embase electronic databases were searched. Reference lists of full-text articles retrieved were reviewed for additional data sources.

Results: Twenty-four primary studies were included. Narrative synthesis resulted in six main …

From Idea To Implementation: Evaluating The Influence Of Large Language Models In Software Development—An Opinion Paper, Sargam Yadav, Asifa Mehmood Qureshi, Abhishek Kaushik, Shubham Sharma, Roisin Loughran, Subramaniam Kazhuparambil, Andrew Shaw, Mohammed Sabry, Niamh St John Lynch, Nikhil Singh, Padraic O'Hara, Pranay Jaiswal, Roshan Chandru, David Lillis

Research Outputs: 2025-Present

The introduction of transformer architecture was a turning point in natural language processing (NLP). Models based on the transformer architecture, such as bidirectional encoder representations from transformers (BERT) and generative pretrained transformer (GPT), have gained widespread popularity in various applications such as software development and education. The availability of large language models (LLMs) such as ChatGPT and Bard to the general public has showcased the tremendous potential of these models and encouraged their integration into various domains such as software development, for tasks such as code generation, debugging, and documentation generation. In this study, opinions from 11 experts regarding their …

En Ritmo: A Praxis In Decolonizing Traditional Dance Spaces, Megan Curet

School of Art, Design and Architecture Theses

En Ritmo: Praxis in Decolonizing Traditional Dance Spaces is an investigation that explores the intersection of bomba, a traditional Puerto Rican song, music and dance form, and North American contemporary dance. This PhD research aims to decolonize culturally hegemonic dance spaces through a cultural syncretism of contemporary dance and the elements of bomba as foundational principles for training both professional and non-professional dancers. This practice challenges traditional Western dance training paradigms. Therefore it is crucial to clarify that this research is not positioned within the realm of pedagogy; rather, it critically interrogates and deconstructs the distinctions between dance practice and …

Diagnosing Long-Term Divergence In Build Back Better Outcomes In Low- And Lower-Middle-Income Communities, E. A. Opabola, M. Baiguera, A. Raby, T. Rossetto, A. Pomonis, E. Meilianda, Y. Idris, S. Nurdin, K. Adams, D. J. Mcgovern, N. Acikgoz, H. Mistry, F. Marafini

School of Engineering, Computing and Mathematics

Low-income communities in disaster-prone regions face persistent challenges in translating post-disaster recovery investments into sustained resilience, as they navigate trade-offs among engineering objectives, policy constraints, and evolving socio-economic needs. Despite the widespread adoption of Build Back Better (BBB) principles, evidence on the long-term sustainability of outcomes remains limited, particularly in low- and lower-middle-income contexts. This study examines the sustainability of BBB outcomes in two Indonesian case studies: Banda Aceh (approximately 18 years after the 2004 Indian Ocean tsunami) and Central Sulawesi (approximately 4 years after the 2018 earthquake, liquefaction, and tsunami). Drawing on structured housing assessments, household surveys, semi-structured interviews, …

Fuzzy Logic-Based Driving Style Classification For Lane-Change Prediction In Intelligent Transportation Systems, Muhammed Fatih Koc, Nouman Ashraf, Pramod Pathak, Sachin Sharma

Research Outputs: 2025-Present

In recent years, Intelligent Transportation Systems (ITSs) have emerged as a solution to mitigate the problem of traffic congestion. Understanding human driving styles such as aggressive, normal, and cautious is crucial for safe driving. In particular, predicting lane-change manoeuvres may be further supported by combining vehicle state information with driving style information. However, existing vehicle trajectory datasets lack driving style information, making classification challenging. To address this limitation, this paper proposes a fuzzy logic-based driving style classification framework in a Vehicle-to-Everything (V2X) environment. The model uses vehicle state information, including speed, longitudinal acceleration, lateral acceleration, and distance headway to classify …

Educating The Next Generation Of Engineers: Spatial Thinking Is Key To Their Success, Sheryl Sorby, Gavin Duffy, Jack Parkinson, Gibin Raju, John Lynch, Muhammad Asghar

Research Outputs: 2025-Present

This paper attempts to answer questions regarding the link between engineering success and spatial skills through three themes. The previous research of the authors in examining the questions surrounding each theme is the focus of this paper; we acknowledge that others around the world may have conducted similar research, but the specific findings of the authors are the main focus of this paper. In the first theme, we examine data from several author-led studies where positive correlations have been found between spatial skill levels and proficiency in tasks that are a part of what it means to be an engineer. …

Sustainable Development And Faith, Tony Kealy

Research Outputs: 2025-Present

The contribution of faith-based input to the broader idea of sustainable development has not been widely acknowledged in the traditional sense; however, recent global events suggest it may warrant further exploration. This qualitative study examines how faith-based activities, such as missionary work, have historically and can continue to contribute significantly to the environmental, economic, and human/social aspects of organizational decision-making. The focus is on the Catholic faith, specifically the role played by the Irish-based Medical Missionaries of Mary religious congregation in the mid-to-late twentieth century. An initial literature review was conducted to gather information from various sources to define sustainable …

Diffusion-Enhanced Nat-Bart Vision Language Transformer For Unified Urdu Word Recognition, Wahid Hussain, Shahbaz Hassan, Isma Ul Hassan, Ahmad Raza Shahid, Asif Naeem, Muhammad Usman Yaseen, Nouman Ashraf

Research Outputs: 2025-Present

Handwritten Urdu text recognition remains a very challenging problem due to the cursive and complex nature of the Nastaliq script. Each writer has a unique style, and there is a severe lack of large, well-labeled datasets. These challenges make Urdu text recognition much harder than for many other languages. Here we propose a novel and effective approach for handwritten Urdu word recognition that addresses both data scarcity and feature complexity. We utilized conditional diffusion models to generate synthetic handwritten Urdu word images. These models produce realistic word samples covering a wide range of variations, such as stroke thickness, curves, and …

Influence Of Beamwidth, Gain Stability, And Antenna Element Spacing On Aoa Accuracy In Ieee 802.15.4z Uwb Systems, Hossein Raghib Hokmabadi, Wasi Ur Rehman Khan, Patrick Mcevoy, Max James Ammann

Research Outputs: 2025-Present

Precision is a crucial requirement in indoor localization, and the industrial sector increasingly demands technologies that provide both high accuracy and low cost. This work presents a hardware-based evaluation of dual-antenna arrays using an IEEE 802.15.4z-compliant UWB angle of arrival (AoA) development kit to assess antenna performance in terms of phase difference of arrival (PDoA)/AoA linearity. Four antenna types: 1) printed monopole; 2) CPW-fed slot; 3) stacked dielectric resonator antenna (DRA); and 4) dual-layer microstrip patch are evaluated on channels 5 and 9, with measurements performed in a calibrated anechoic chamber under controlled conditions. The results show that wide beamwidth …

Mission-Focused Multidisciplinary Design Optimization Of Tilt-Rotor Evtol Propulsion System, Tyler Critchfield, Andrew Ning

Faculty Publications

Tilt-rotor propulsion system design requires a multidisciplinary approach to tackle important challenges and competing tradeoffs between disciplines. In this paper, we model rotor aerodynamics, blade structures, vehicle drag, electric propulsion, and tonal/broadband acoustics for a tilt-rotor, electric vertical takeoff and landing aircraft using low-to-mid fidelity tools. We use gradient-based design optimization with automatic differentiation and parameter sensitivity analyses to explore the design space and complex tradeoffs of tilt-rotor distributed electric propulsion systems, exploring effects of variations in payload/empty weight, battery specific energy, and blade tip speed. This framework models multiple operating points with a mission-focused objective to account for the …

Microbial Collagenase Activity Is Linked To Oral–Gut Translocation In Advanced Chronic Liver Disease, Shen Jin, Aurelie Cenier, Daniela Wetzel, Bethlehem Arefaine, Mar Moreno-Gonzalez, Marilena Stamouli, Merianne Mohamad, Mariia Lupatsii, Emilio Ríos, Sunjae Lee, Ane Zamalloa, Shilpa Chokshi, Adil Mardinoglu, Saeed Shoaie, Naiara Beraza, Vishal C. Patel, Melanie Schirmer

Peninsula Medical School

Microbiome perturbations are associated with advanced chronic liver disease (ACLD), but how microorganisms contribute to disease mechanisms is unclear. Here we analysed metagenomes of paired saliva and faecal samples from an ACLD cohort of 86 individuals, plus 2 control groups of 52 healthy individuals and 14 patients with sepsis. We identified highly similar oral and gut bacterial strains, including Veillonella and Streptococcus spp., which increased in absolute abundance in the gut of patients with ACLD compared with controls. These microbial translocators uniquely share a prtC gene encoding a collagenase-like proteinase, and its faecal abundance was a robust ACLD biomarker (area …

Usable Authentication: Are We There Yet?, Nathan Clarke, Steven Furnell

School of Engineering, Computing and Mathematics

With technology increasingly embedded in everyday life, the demand for secure and usable authentication methods has never been greater. Traditional password-based systems continue to dominate, despite well-known usability and security challenges. This paper explores the evolution of user authentication technologies, from secret knowledge and tokens to biometrics and emerging approaches such as Passkeys. It critically evaluates the extent to which usability has been achieved, identifying both successes—such as biometrics integrated into smartphones—and persistent issues, including inconsistent guidance, ecosystem dependence, and accessibility barriers. Drawing on academic and commercial developments, the discussion highlights the growing burden on users who must authenticate across …

Biocompatibility Of Silver And Hydroxyapatite Antimicrobial Nanocoatings On Titanium Alloy Dental Implants With Human Gingival Fibroblasts, S Morgan, R D Handy, V M Salih, R N Salaie, C J Tredwin, A Besinis

School of Engineering, Computing and Mathematics

OBJECTIVES: Peri-implantitis compromises soft and hard tissues around dental implants, often leading to implant failure. Antibacterial nanocoatings offer a promising infection control strategy, but maintaining biocompatibility is essential. This study investigated, through a range of assays and analytical techniques, the biocompatibility of antimicrobial silver and hydroxyapatite (HA) nanocoatings applied to titanium implants with human gingival fibroblasts (HGFs).

METHODS: Silver and hydroxyapatite nanocoatings were applied to the surface of titanium alloy specimens using electroplating, deposition and sintering techniques. The biocompatibility of the nanocoatings with HGFs was assessed by measuring cell metabolic activity (alamarBlue), lactate dehydrogenase (LDH) release, collagen production (Sircol assay), …

Presence And Characteristics Of Plastics And Microplastics On The Seabed Of The Western English Channel, Faye Read, Andrew Turner

School of Geography, Earth and Environmental Sciences

Little is known about the presence, distribution, origins and characteristics of plastic litter and microplastics on the ocean floor. In this study, plastics trawled from the bed of the western English Channel have been categorised and analysed by a variety of optical and spectroscopic techniques. A total of 90 plastic samples were classified, in descending order of abundance, as food-drink packaging, unknown, homeware, military and fishing. Most samples showed varying degrees of weathering (e.g., discolouration, distortion, cracking, fragmentation) and were visibly fouled by calcareous deposits. The majority of samples were constructed of polymers of negative buoyancy (e.g., polyamides, polyethylene terephthalate …

A Unified Framework For Evaluating Training Efficiency In Deep (Bayesian) Neural Networks: Metrics, Overtraining, Stopping Criteria, And Grokking Computer Science, Eduardo Cueto Mendoza

Doctoral

Measuring training efficiency for artificial neural networks is an open research problem, current literature reports several attempts to define measures or create reporting frameworks. Current methods lack generality as they require measurements of the hardware or software thus, comparing efficiency between different systems can be difficult. Similarly, current metrics or frameworks generally do not propose the use of the metrics to directly improve training efficiency. This thesis presents three main contributions: (1) a novel framework that quantifies the training efficiency of a neural architecture on a learning task as the average ratio of model accuracy to total energy consumption during …

Job Satisfaction, Burnout, And Intent To Stay In Neonatal Nursing In England And Wales: A Cross-Sectional Survey Study, Kathy Chant, Yoko Nishimura, Aviva Petrie, Jos M. Latour, Nicola Booth, Kelly Crofts, Lisa Viola, Katie Gallagher

School of Nursing and Midwifery

Objective: To explore job satisfaction, burnout and intent to stay in neonatal nurses in England and Wales. Methods: A cross-sectional online survey study using the McCloskey Mueller Satisfaction Scale (MMSS) to explore job satisfaction, the Copenhagen Burnout Inventory (CBI) to explore burnout and the Nurse Retention Index (NRI) to measure intent to stay. All neonatal nurses working in England and Wales were eligible to take part. Data were collected between February and September 2024. Results: A total of 1590 neonatal nurses completed the survey. Job satisfaction was neutral. Moderate work burnout was reported, with statistically significant differences in mean score …

Integrating Environmental Awareness In Underwater Acoustic Networks: A Comprehensive Review, Sadaf Vahabli, Iftekhar Ahmad, Quoc Viet Phung, Daryoush Habibi, Walid K. Hasan, Ruba Zaheer

Research outputs 2022 to 2026

Underwater Acoustic Networks (UANs) are critical for enabling long-range underwater communication, supporting a wide range of applications, such as environmental monitoring, resource exploration, disaster prevention and marine security. Unfortunately, UANs operate within a limited acoustic spectrum, where these spectrums often overlap with those used by marine animals for communication, navigation and foraging. Additionally, anthropogenic noise from industrial activities contributes to acoustic pollution, intensifying this problem. This frequency overlap poses significant risks to marine life. Therefore, this review highlights the urgent need to develop environmentally aware UANs that minimize harmful acoustic interference with marine mammals, fish and invertebrates. Further, it focuses …

Human Capability Development In Irish Tech Smes, Anna Zherdeva

Doctoral

Purpose: SMEs are the backbone of the European economic model and represent 99.8% of all businesses, highlighting the importance of research that assesses challenges and opportunities faced by SMEs. The reviewed literature revealed a significant lack of research on how SMEs can develop management, teamwork, and team-building skills in the context of the twin transition (i.e., digital and green transitions), particularly regarding digital transformation and its impact on economic development and business cooperation. Researchers have presented evidence of the difficulties SMEs face in competing with corporations due to numerous constraints, including a lack of investment and qualified human resources. To …

Mapping The Uk Commercial Fishing Network: A Knowledge-Based Framework For Sustainable Technology Adoption And Environmental Decision-Making, Matthew Prowse

School of Engineering, Computing and Mathematics Theses

The UK commercial fishing industry operates within a complex web of stakeholders, technologies, and environmental pressures that challenge traditional approaches to sustainability and resource management. This research develops a comprehensive framework for understanding how technological advancement in UK fisheries creates unintended consequences that threaten long-term sustainability. Through a mixed-methods approach combining PESTLE analysis, grounded theory methodology, stakeholder mapping, case study investigation, this study introduces the "By-Product and Excess" theoretical framework to explain how fishing technologies generate two critical outcomes: by-products (undesirable environmental impacts such as CO₂ emissions, microplastics, and ecosystem damage) and excess (enhanced capacity to harvest beyond sustainable limits).The …

A General Tool To Assist With On Orbit Manufacturing, Richard Arundal

School of Engineering, Computing and Mathematics Theses

On-Orbit Manufacturing (OOM) presents a transformative paradigm in space mission design, enabling the in-situ production of components, tools, and large-scale structures beyond terrestrial constraints. This dissertation investigates the feasibility of OOM missions by developing a modular, iterative algorithm to support early-stage mission design and scenario analysis. The central hypothesis is that such an algorithm can be parameterised to evaluate a wide spectrum of manufacturing cases in space, ranging from small utility items to large structural systems.The research pursues four core objectives: assessing the terrestrial manufacturing lifecycle and its applicability in the space environment; identifying candidate manufacturing techniques suitable for orbital …

Understanding The Epigenetic Landscape Of Barrett's Esophagus And Esophageal Cancer: A Review Of Current Findings, Caveats And Future Directions, Louise Lawless, Trevor Doherty, Carla Surlis, Niamh Gilmartin, Therese M. Murphy

Research Outputs: 2025-Present

Esophageal cancer (OC) is currently the eighth most common form of cancer worldwide with a 5-year survival rate of 10%–20%, with the primary risk factor of esophageal adenocarcinoma (OAC) being the development of Barrett's Esophagus (BO). Despite its clinical significance, the molecular pathogenesis underlying both BO and OC is not well understood. In recent years, epigenetic dysregulation, particularly aberrant DNA methylation, has emerged as a critical area of investigation, given its potential utility in the identification of diagnostic, prognostic, and therapeutic biomarkers. This review examines the evolving epigenetic landscape of esophageal cancer, including a focus on its origins in BO …

‘Male Victims Of ‘Honour Crimes’: A Critical Examination Of The Concepts Of ‘Honour’ And The Wider Debates Surrounding ‘So-Called Honour-Based Violence’ And ‘Hate Crime’, Narissa Maclennan-Matthews

School of Law, Humanities and Social Sciences Theses

This thesis critically interrogates the experiences of male victims of ‘so-called honour-based violence and abuse’ (SCHBVA) through an intersectional criminological framework. It draws primarily on Barbara Perry’s theories of ‘Doing Difference’ (2001; 2003) and the ‘in terrorem effects’ of hate crime (Perry & Alvi, 2012), alongside insights from Structural Criminology (Hartjen, 1978; Kramer, 1985) and Humanistic Criminology (Hagan, 1986). Drawing on semi-structured interviews with male survivors and criminal justice professionals, and employing thematic and case study analysis, the study examines how violence is produced and legitimised across intersecting axes of gender, sexuality, ethnicity, and religion.Building on Perry’s conceptualisation of ‘Doing …

A Murder Of Sleuths: A Novel And A Critical Exploration Of Cosy Crime And The Digital/Analogue Binary Through Websleuthing, Olivia Templeton

School of Law, Humanities and Social Sciences Theses

My project is comprised of two elements. The first is practice led research taking the form of a novel titled A Murder Of Sleuths. This investigates how the Cosy Crime subgenre might be modified and impacted by the digital nature of the contemporary world. I explore this by taking the key traditional features of the Cosy Crime structure, in particular the manor house setting, the small isolated village, and the amateur sleuth and detective relationship and merging it with the character of Dora Grant, a Websleuth who uses technology and the internet as tools to solve crime. Dora's investment in …