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Physical And Psychophysiological Responses To Self-Selected Music In Individuals With Parkinson's Disease, Sophia Porrill Jan 2026

Physical And Psychophysiological Responses To Self-Selected Music In Individuals With Parkinson's Disease, Sophia Porrill

ETDs from 2020-2029

Exercise is a cornerstone adjunct therapy for people with Parkinson’s Disease (PwP). However, exercise capacity is often impaired by non-motor processes including decreased motivation, arousal, and physical effort. Self-selected music (SSM) has been shown to improve motivation and arousal state in healthy individuals thereby leading to increases in exercise capacity. Whether these positive effects of SSM translate to PwP is unclear. The purpose of this study was to measure 1) the psychophysiological effects of SSM at rest, and 2) psychophysiological and physical responses during a 6-minute walk test (6MWT) in PwP. In a counterbalanced crossover manner, PwP (n=12) completed resting …


Analysis Of Activated Carbon Fiber (Acf) As Particulate Filtration And Volatile Organic Compound (Voc) Media For The Development Of A Dual-Air Purifying Facepiece Respirator, Brie Mcmahan Jan 2026

Analysis Of Activated Carbon Fiber (Acf) As Particulate Filtration And Volatile Organic Compound (Voc) Media For The Development Of A Dual-Air Purifying Facepiece Respirator, Brie Mcmahan

ETDs from 2020-2029

Exposure to particulate matter (PM) and volatile organic compounds (VOCs) in occupational or public settings poses adverse health outcomes such as respiratory, cardiovascular, reproductive, neurological, carcinogenic morbidity and mortality. Many occupational settings expose workers to PM and VOC concurrently, yet most commercially available respirators are designed to address either particulates or vapors alone. This includes air-purifying respirators (APRs), powered air-purifying respirators (PAPRs), and filtering facepiece respirators (FFRs) with nuisance-level vapor protection, often limited by bulk, discomfort, high pressure drop, and misuse. We identified a need for alternative dual-exposure media and a respiratory protection device that is lighter, and more comfortable …


Understanding Mobility Limitations And Public Transportation Accessibility For People With Disabilities, Jada Meria Stringer Jan 2026

Understanding Mobility Limitations And Public Transportation Accessibility For People With Disabilities, Jada Meria Stringer

ETDs from 2020-2029

Mobility for people with disabilities (PWDs) depends on both the availability of transportation and public services and the accessibility of these systems. The presence of public transportation systems does not ensure usability. Vehicles, infrastructure, and the built environment must be designed to accommodate diverse physical, sensory, cognitive, and other needs. PWDs must also be able to navigate public buildings and surrounding spaces safely and comfortably. This thesis examines mobility limitations for PWDs in India and the United States, focusing on accessibility along the full mobility chain. A review of existing literature provides context on accessibility policies, design standards, and the …


Biomineralization Of Low Temperature Plasma(Ltp) Modified Polymeric Biomaterials And Scaffolds, John Patrick Bradford Jan 2026

Biomineralization Of Low Temperature Plasma(Ltp) Modified Polymeric Biomaterials And Scaffolds, John Patrick Bradford

ETDs from 2020-2029

Bio-integration, specifically osseo-integration of bone implants and scaffolds, are vital for the success of implants and bone tissue engineering (BTE). Calcification can be defined as the deposition of calcium compounds as either calcium phosphate(CaP) minerals consisting of hydroxyapatite(HAP) or CaP salts. The significance of the variety of phases of CaP is that mature bone matrix is composed of 65% CaP mineral. Many investigators have attempted to model the natural matrix by producing materials containing calcium phosphate in both amorphous CaP or in the more crystalline HAP form, with biomaterials (both synthetic and biological). Biomimetic CaP formation is a sign of …


Development Of Human Trophoblast Cell Surface Antigen-2 (Trop-2) Specific Radiopharmaceutical Tracers, Arnav Vipulkumar Patel Jan 2026

Development Of Human Trophoblast Cell Surface Antigen-2 (Trop-2) Specific Radiopharmaceutical Tracers, Arnav Vipulkumar Patel

ETDs from 2020-2029

Trophoblast cell surface antigen 2 (Trop2) is closely related to the development and progression of triple-negative breast cancers (TNBC) and is also being investigated as a pan-cancer biomarker. Trop-2 tumorigenesis is mediated by the calcium ion signaling pathways. By accurately predicting and targeting Trop-2 for immunotherapy, precision therapy is crucial. Trop-2 is overexpressed in tumor tissues compared to normal tissues, which makes it a promising molecular target for cancer-targeted therapy. This thesis reports the development and preclinical evaluation of two novel Trop-2-specific radiopharmaceutical tracers derived from the clinically approved antibody-drug conjugate Sacituzumab Govitecan (SG): a full antibody drug conjugate-based tracer …


Quantum Technologies, Part One: Focusing A Bit Upon Realities, James Giordano Jan 2026

Quantum Technologies, Part One: Focusing A Bit Upon Realities, James Giordano

Strategic Insights

This commentary examines the current realities of quantum technologies and their implications for national security and defense. While quantum systems are often described as revolutionary, their practical military impact remains uneven and frequently overstated. This analysis reviews three key domains—quantum computing, sensing, and communications, and explains where these technologies currently outperform classical systems and where significant technical limitations remain. In particular, quantum computing is still in a “noisy, intermediate-scale” stage, meaning most applications remain experimental and dependent on advances in error correction, algorithms, and hardware. Understanding both the promise and limitations of quantum technologies is essential for shaping realistic defense …


Derivative Attorney-Client Privilege In Organizations, Douglas R. Richmond Jan 2026

Derivative Attorney-Client Privilege In Organizations, Douglas R. Richmond

University of Miami Business Law Review

A lawyer and client must be able to communicate about the client’s legal affairs in confidence for the lawyer to be able to meaningfully advise the client, hence courts’ recognition of the attorney-client privilege. Fundamentally, the very term “attorney-client privilege” seemingly requires a lawyer’s participation in a communication for the privilege to attach. But, in fact, lawyers need not always participate in client communications for the attorney-client privilege to shield the communications from discovery. Clients or their employees’ confidential conversations among themselves with respect to legal matters sometimes deserve privilege protection. This derivative application of the privilege can be crucial …


Effects Of Leucine Supplementation On Athletic Performance, Central Fatigue, And Serum Metabolism In Endurance Athletes: A Randomized Controlled Trial And Targeted Metabolomics Study, Tieying Li, Wei Xu, Jun Chen, Zhaobo Kan, Xuemei Sui, Zhiguang Zhao, Qirong Wang Jan 2026

Effects Of Leucine Supplementation On Athletic Performance, Central Fatigue, And Serum Metabolism In Endurance Athletes: A Randomized Controlled Trial And Targeted Metabolomics Study, Tieying Li, Wei Xu, Jun Chen, Zhaobo Kan, Xuemei Sui, Zhiguang Zhao, Qirong Wang

Faculty Publications

Objectives: We aimed to investigate the effects of 6 weeks of leucine supplementation on athletic performance, central fatigue, and serum metabolome in endurance athletes, and to provide valuable insights into nutritional strategies for endurance athletes. Methods: Twenty cross-country skiers were recruited and randomized into 2 groups: the placebo (PLA) group and the leucine (LEU) group. Subjects were given leucine (8.5 g) + sucrose (14 g) or only sucrose (14 g) supplements twice each day from Monday to Saturday for 6 weeks. Test parameters include body composition, aerobic capacity, isokinetic muscle strength, blood biochemistry, and targeted metabolomics. Results: After intervention, compared …


Minutes, Curriculum Committee Meeting, Tuesday, January 27, 2026, Curriculum Committee Jan 2026

Minutes, Curriculum Committee Meeting, Tuesday, January 27, 2026, Curriculum Committee

Curriculum Committee Minutes

No abstract provided.


Expanding Access To Live Donation Opportunities: Implementing Telehealth Solutions To Enhance The Living Donor Navigator Program, Alexis Carter Jan 2026

Expanding Access To Live Donation Opportunities: Implementing Telehealth Solutions To Enhance The Living Donor Navigator Program, Alexis Carter

ETDs from 2020-2029

Living donor kidney transplantation (LDKT) is the most effective treatment for patients with end-stage kidney disease; however, living donation rates have remained suboptimal over the past two decades. As a result, many interventions have been developed and tailored to increase living donation. The Living Donor Navigator (LDN) Program is one effort designed to help transplant candidates identify potential living donors and guide them through the donation process, using a combination of advocacy and systems training. The LDN Program is a lay-navigator-based intervention that equips participants with the knowledge, communication skills, and confidence needed to identify and engage potential living donors. …


Novel Retinal Biomarker Development In Early Alzheimer’S Disease, Swetha Ravichandran Jan 2026

Novel Retinal Biomarker Development In Early Alzheimer’S Disease, Swetha Ravichandran

ETDs from 2020-2029

Alzheimer’s disease is a progressive neurodegenerative disorder that causes damage to the neurons that are present in the brain. Progress in the management and treatment of AD is limited by lack of early diagnostics, which are critical to the development of effective therapies. It is therefore critical to develop non-invasive/cost efficient biomarkers to aid in early diagnosis and interventions to prevent or delay dementia onset. While Positron Emission Tomography (PET) and cerebrospinal fluid assessment have greatest utility, they are not routinely used because they are expensive and invasive, respectively. Retinal imaging offers a promising, low-cost, and non-invasive avenue for detecting …


Awareness And Knowledge Of Juvenile Idiopathic Arthritis Among Orthodontic And Oral And Maxillofacial Surgery Specialties In The United States., Kavita Nayar Jan 2026

Awareness And Knowledge Of Juvenile Idiopathic Arthritis Among Orthodontic And Oral And Maxillofacial Surgery Specialties In The United States., Kavita Nayar

ETDs from 2020-2029

Introduction: Juvenile Idiopathic Arthritis (JIA) is the most common chronic pediatric arthritis, frequently involving the temporomandibular joint (TMJ) and resulting in facial growth disturbances, functional impairment, and complex multidisciplinary treatment needs. Despite its clinical relevance, limited awareness and inconsistent management strategies exist among specialists who are involved in the care of these patients including orthodontists, oral and maxillofacial surgeons and rheumatologists. This study aimed to evaluate the understanding, knowledge and interdisciplinary management practices between board-certified orthodontists and oral and maxillofacial surgeons (OMSs) across the United States regarding JIA. Materials and Methods: A cross-sectional survey was distributed electronically via Qualtrics to …


Nutritional Care For Adults With Obesity Treated With Glp-1and Dual Gip/Glp-1 Receptor Agonists: A Review Of Evidence, Gaps, And Clinical Implications, Carolina Mcguane Jan 2026

Nutritional Care For Adults With Obesity Treated With Glp-1and Dual Gip/Glp-1 Receptor Agonists: A Review Of Evidence, Gaps, And Clinical Implications, Carolina Mcguane

Department of Nutrition Student Projects

Abstract

Background:

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 receptor agonists (GIP/GLP-1 RAs) have revolutionized obesity management, producing unprecedented weight loss outcomes. Their widespread use has outpaced research on nutritional implications, adverse events, and evidence-based guidance for dietitians. Given the central role of nutrition practitioners in supporting adults with obesity, understanding the mechanisms, risks, and nutrition-related outcomes of GLP-1 therapies is critical.

Methods:

A comprehensive literature search was conducted utilizing PubMed, Embase, and Google Scholar to identify relevant peer-reviewed articles on the topic of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) use and nutrition-related …


How To Finalize Pdfs To Correspond To American Disabilities Act (Ada) Tagging: The Basics, Kimberly Holling Jan 2026

How To Finalize Pdfs To Correspond To American Disabilities Act (Ada) Tagging: The Basics, Kimberly Holling

ScholarWorks Publications

This document is a basic step-by-step outline for tagging a PDF file in accordance with the American Disabilities Act (ADA).  ADA tagging allows a digital document to work well with screen readers in order to assist those with visual impairments to more fully engage with a document's content.  This is not a comprehensive guide, as it will not cover forms or complex tables.  This specific workflow shows how to use Adobe Acrobat Pro to work with, finalize, and verify accessibility in PDFs created from simple Word documents.  Such documents should already use Word heading and list features and very simple …


Exploring The Relationship Among Nurse-Specific Factors And Triage Accuracy In The Emergency Setting, Krisada Suamchaiyaphum Jan 2026

Exploring The Relationship Among Nurse-Specific Factors And Triage Accuracy In The Emergency Setting, Krisada Suamchaiyaphum

ETDs from 2020-2029

Triage is a critical function of emergency nursing practice, directly influencing patient safety, flow, and outcomes in the emergency department (ED). Despite widespread use of standardized triage training and resources, triage accuracy among ED nurses remains suboptimal. The purpose of this three-manuscript dissertation was to examine factors associated with triage accuracy in the ED setting. Manuscript One was an integrative literature review of 14 studies published between 2011 and 2021, with reported triage accuracy rates ranging from 59.3% to 82%. Primary factors associated with triage accuracy were: nurse-specific, patient, and work environment factors. Manuscript Two reported a retrospective study of …


Psychosocial Outcomes In Adults With Cleft Lip And Palate: Exploring The Relationship Between Cleft Severity, Mental Health, And Treatment Satisfaction, Haley Hannabass Jan 2026

Psychosocial Outcomes In Adults With Cleft Lip And Palate: Exploring The Relationship Between Cleft Severity, Mental Health, And Treatment Satisfaction, Haley Hannabass

ETDs from 2020-2029

Introduction:This study aimed to examine psychosocial outcomes in adults with cleft lip and palate (CL/P), focusing on how cleft severity (unilateral versus bilateral) influences depression, anxiety, social functioning, oral health–related quality of life, and satisfaction with treatment outcomes. Individuals born with clefts often continue to face psychosocial challenges even after surgical repair, and limited research has compared how these outcomes differ by cleft type in adulthood. Materials and Methods:A cross-sectional design was used, including 24 adults aged 18 years and older who had undergone cleft repair and were finished or in active orthodontic treatment at UAB. Participants completed an online …


Handling Missing Data In Copd Research, Chia-Ying Chiu Jan 2026

Handling Missing Data In Copd Research, Chia-Ying Chiu

ETDs from 2020-2029

Chronic Obstructive Pulmonary Disease (COPD) remains a major global health concern and one of the leading causes of death in the United States, affecting approximately 4.6% of adults and reaching a prevalence of 9.4% in Alabama according to 2024 National Health Interview Survey. The disease imposes a substantial burden on quality of life and healthcare costs and contributes to increased disability-adjusted life years and years of life lost, as highlighted by the 2022 Lancet Commission report. Despite its im-pact, COPD is frequently diagnosed only after irreversible lung damage has occurred, largely due to under-recognized symptoms and limited diagnostic tools. Early …


Development Of Salinomycin Analogs As Potential Anti-Cancer Agents, Pavan Goud Juluri Jan 2026

Development Of Salinomycin Analogs As Potential Anti-Cancer Agents, Pavan Goud Juluri

Theses and Dissertations

Salinomycin, a poly-ionophore antibiotic originally isolated from Streptomyces albus, exhibits antimicrobial activity against Gram-positive bacteria. Over the years Salinomycin has been studied in the effects it has on cancer, specifically cancer stem cells. Poly(ADP-ribose) polymerase (PARP) is an enzyme involved in DNA repair. Inhibiting PARP has been explored as a strategy in cancer treatment, particularly in cancers with defective DNA repair mechanisms, such as those with BRCA mutations. The benzo-thiazoles, and -imidazoles are identified as inhibitor scaffolds, which compete with nicotinamide in the binding pocket of human poly- and mono-ADP-ribosylating enzymes. Benzothiazole, and benzimidazole based compounds particularly with modification at …


Hard Hats And Second Chances: A Phenomenological Study Of Employer Support In Construction-Based Reintegration, Christofer M. Pacheco Jan 2026

Hard Hats And Second Chances: A Phenomenological Study Of Employer Support In Construction-Based Reintegration, Christofer M. Pacheco

USF Tampa Graduate Theses and Dissertations

This qualitative phenomenological study examines how formerly incarcerated individuals perceive and experience employer support during workplace reintegration in the construction industry. Although employment is widely recognized as a protective factor against recidivism, post-hire experiences from the perspective of justice-involved employees remain underexplored. Grounded in an interpretivist paradigm and informed by Social Support, Social Learning, and Identity perspectives, the study investigated how structure, self, and environment interact to influence retention, growth, and desistance.

Nineteen interviews were completed with six construction workers in New Mexico who had maintained employment for at least one year following incarceration. Through the use of Seidman’s three-interview …


Advanced Experimental Learning And Behavior Analysis Lab Manual, Holly R. Weisberg, Sally Izquierdo Jan 2026

Advanced Experimental Learning And Behavior Analysis Lab Manual, Holly R. Weisberg, Sally Izquierdo

Open Educational Resources

Classroom and online lab exercises for a learning and applied behavior analysis course.


Assessing Mangrove Ecosystem Health And Identifying Optimal Planting Regions Using Remote Sensing And Gis In The Uae, Imen Ben Salem, A. Karthi, Yousef Nazzal Jan 2026

Assessing Mangrove Ecosystem Health And Identifying Optimal Planting Regions Using Remote Sensing And Gis In The Uae, Imen Ben Salem, A. Karthi, Yousef Nazzal

All Works

Mangrove forests play a critical role in carbon sequestration, biodiversity preservation, and coastal resilience, making their conservation and restoration essential in climate change mitigation. This study uses traditional field evaluations and remote sensing and geoinformatics (GIS) methods to examine how mangrove ecosystems in the United Arab Emirates (UAE) have changed over time and space. We used Landsat satellite data from 2001 to 2024 and a set of vegetation indices, including SMRI, NDVI, GNDVI, EVI, and NDCI, to examine spatial patterns in biomass distribution, vegetation density, and overall ecosystem health. CO2 sequestration is a bit more climate-impact resilient. Even though the …


Examining Pain- Related Stigma And Sources Of Resilience In Children With Disorders Of Gut-Brain Interaction, Tolulope Adetayo Jan 2026

Examining Pain- Related Stigma And Sources Of Resilience In Children With Disorders Of Gut-Brain Interaction, Tolulope Adetayo

ETDs from 2020-2029

Background. Painful disorders of gut-brain interaction (DGBI) affect approximately one in five children. In addition to functional impairments, DGBI increase risk for felt stigma (FS) from providers, school personnel, family members, and peers. Children with DGBI may also belong to other minoritized groups that intersect with pain-related FS. However, little is known about how intersectionality impacts the stigma and pain experiences of youth. Further, little is known about the protective capabilities of psychosocial resources (e.g., social support and hope) against FS. Thus, the current study aimed to investigate the impact of FS and its potential moderators in a sample of …


Ultrafast Terahertz Spectroscopy And The Suppression Of Superconductivity In Strained Iron Selenide Below 1 Kelvin, Tracy Glen Hastings Jan 2026

Ultrafast Terahertz Spectroscopy And The Suppression Of Superconductivity In Strained Iron Selenide Below 1 Kelvin, Tracy Glen Hastings

ETDs from 2020-2029

We report on terahertz time-domain spectroscopy measurements of iron selenide thin films of various thicknesses grown on a magnesium oxide substrate, focusing on the frequency-dependent complex conductivity in the range of 0.25 - 7 THz. By an- alyzing films with and without an approximately 100 nm thick Se capping layer, we examined the role of oxidation in the suppression of superconductivity. X-ray photo- electron spectroscopy data confirmed that oxidation was effectively mitigated, yet the films exhibited insulating behavior down to 200 mK, a temperature range that has not been extensively studied in this system. Our results indicate that the suppression …


Posterior Cerebellar Lobe Deviations And Social Cognition In Individuals With Psychosis And Their Unaffected Relatives, Andreea Maria Stanica Jan 2026

Posterior Cerebellar Lobe Deviations And Social Cognition In Individuals With Psychosis And Their Unaffected Relatives, Andreea Maria Stanica

ETDs from 2020-2029

Social cognition deficits observed in psychotic disorders contribute to functional impairments. The cerebellum has been identified as a critical brain region involved in social cognitive processes, but the relationship between cerebellar structural deviations and social cognition in individuals with psychosis (probands) and their unaffected relatives remains unclear. Using normative modeling, this study examined cerebellar volume deviations in probands and their unaffected first-degree relatives and investigated associations with social cognitive and motor performance. Probands exhibited significant theory of mind deficits compared to relatives. Probands showed negative deviations in anterior cerebellar lobe relative to the norm, whereas relatives did not. Deviations in …


The Effectiveness Of A Web-Based, Edutainment Intervention On Hiv-Related Stigma, Hiv Knowledge, And Condom Use Self-Efficacy Among Black/African American Emerging Adults, Shirlacia Gray Jan 2026

The Effectiveness Of A Web-Based, Edutainment Intervention On Hiv-Related Stigma, Hiv Knowledge, And Condom Use Self-Efficacy Among Black/African American Emerging Adults, Shirlacia Gray

ETDs from 2020-2029

The Effectiveness of a Web-Based, Edutainment Intervention on HIV-Related Stigma, HIV Knowledge, and Condom Use Self-Efficacy among Black/African American Emerging Adults SHIRLACIA S. GRAY APPLIED DEVELOPMENTAL PSYCHOLOGY ABSTRACT Background: Edutainment interventions were developed to increase knowledge, to influence people’s attitudes and behaviors toward sexual, social and public health issues, and to promote behavior change. This current study implemented an edutainment intervention to examine its effectiveness on increasing HIV knowledge, reducing HIV-related stigma, and increasing condom use self-efficacy among Black/African American Emerging Adults in Birmingham, AL. Methods: This current study used longitudinal data from the City Health-II intervention for secondary data …


Exploring Criminality Through A Developmental Lens: Contextual Effects From Childhood To Emerging Adulthood, Abigail Jeanette Anderson Jan 2026

Exploring Criminality Through A Developmental Lens: Contextual Effects From Childhood To Emerging Adulthood, Abigail Jeanette Anderson

ETDs from 2020-2029

Adolescent delinquency is a key predictor of later criminal behaviors and is associated with negative outcomes across education, employment, and health. Despite extensive research, gaps remain regarding the interplay of individual- and context-level factors in the development of delinquency, as well as the reliance on cross-sectional or retrospective designs. Guided by a social-ecological framework, the present dissertation examines how family, school, and neighborhood contexts interact with individual behaviors to shape pathways toward delinquency and adult criminality across childhood, adolescence, and early adulthood. The first study investigated the cascading effects of paternal engagement, parental aggravation, and early child behavior problems in …


Amino Acid Pet Tracers For Cancer Imaging And Response Assessment, Ugur Akca Jan 2026

Amino Acid Pet Tracers For Cancer Imaging And Response Assessment, Ugur Akca

ETDs from 2020-2029

Triple-negative breast cancer (TNBC) and high-grade glioma (HGG) pose significant diagnostic and therapeutic challenges due to their aggressive biology and the limitations of [¹⁸F]FDG PET, which suffers from nonspecific uptake in inflammatory tissues, complicating differentiation of viable tumor from treatment-related effects. Computed Tomography, while strong for structural changes, has limited soft tissue contrast for distinguishing tumor from inflammation, and Magnetic Resonance Imaging, despite superior soft tissue resolution, struggles with differentiating active tumor from post-treatment changes like edema or necrosis due to nonspecific enhancement. These challenges highlight the necessity for complementary and advanced imaging strategies for improved diagnosis and monitoring. This …


Bidirectional Effects Of Transcutaneous Auricular Vagus Nerve Stimulation On Insomnia And Brain Health In Breast Cancer, Melissa Van Trang Do Jan 2026

Bidirectional Effects Of Transcutaneous Auricular Vagus Nerve Stimulation On Insomnia And Brain Health In Breast Cancer, Melissa Van Trang Do

ETDs from 2020-2029

Breast cancer remains the most frequently diagnosed cancer among women worldwide, with over 2.3 million new cases annually. While advances in treatment have improved survival, many women continue to suffer from persistent insomnia, fatigue, anxiety, depression, and cognitive dysfunction that collectively impair quality of life and recovery. These interrelated symptoms share common biological underpinnings, including autonomic dysregulation, vagal withdrawal, and chronic inflammation. Transcutaneous auricular vagus nerve stimulation (taVNS) is a non-invasive, bioelectronic therapy that modulates afferent vagal pathways via auricular branches of the vagus and trigeminal nerves. By engaging central autonomic and neuroimmune circuits, including the nucleus tractus solitarius and …


Sample Preparation Effects On Liquid Scintillation Counting Quench, Jason Rusch Jan 2026

Sample Preparation Effects On Liquid Scintillation Counting Quench, Jason Rusch

ETDs from 2020-2029

Liquid Scintillation Counting (LSC) is a critical technique in operational health physics, particularly for contamination surveys. However, common, expedient sample preparation choices often introduce unpredictable levels of quench, compromising the accuracy of results. This thesis investigates the impact of common preparation variables including vial material, cap lining, solid sample matrix presence, cocktail volume, and radioactivity. The impact of these sample preparation variables were evaluated using the quench methods on two fundamentally distinct commercial LSC systems, the Perkin Elmer Tri-Carb 4910TR (employing tSIE correction) and the Hidex 600 SL (employing TDCR correction). A total of 320 samples were evaluated on each …


Physiological And Neuroimmune Effects Of Manual Therapy, Murdi S. Alanazi Jan 2026

Physiological And Neuroimmune Effects Of Manual Therapy, Murdi S. Alanazi

ETDs from 2020-2029

Manual therapy (MT) is widely used across healthcare disciplines for the management of musculoskeletal conditions. Emerging evidence indicates that MT may also influence broader physiological systems such as the nervous and the immune systems. However, the mechanisms underlying these effects are still not well understood, and limited evidence exists regarding the neuroimmune effect of MT in neurologically impaired populations such as multiple sclerosis (MS). The overall aim of this dissertation was to investigate the physiological effects of MT, synthesizing current evidence across mechanistic domains, and generating pilot data to inform future research. This dissertation was structured around four manuscripts. The …