Digital Commons Network^™

Cost-Effectiveness Of Pregabalin, Duloxetine, And Milnacipran Vs Amitriptyline For Moderate To Severe Fibromyalgia, Sarah S. Downen, Hussein M. Farag, Abby Davis, Chijioke M. Okeke, Kenechukwu C. Ben-Umeh, Ismaeel Yunusa Ph.D., Tewodros Eguale

Faculty Publications

Importance

Fibromyalgia (FM) is a chronic pain condition associated with substantial quality-of-life impairments and economic burden. Although multiple pharmacologic options are recommended in clinical guidelines, the relative cost-effectiveness of off-label amitriptyline compared with FDA-approved treatments remains poorly defined due to a scarcity of direct economic comparisons and the use of heterogenous outcome measures in the extant literature.

Objective

To evaluate the cost-effectiveness of pregabalin, duloxetine, and milnacipran compared with amitriptyline in adults with moderate to severe FM.

Design, Setting, and Participants

Decision analytical model using a Markov cohort state transition model to estimate lifetime costs and quality-adjusted life-years (QALYs) for …

Faculty Senate Meeting, 60th Senate Recording (2/3/2026), Csusb Faculty Senate

CSUSB Faculty Senate records

No abstract provided.

Usa V. Dameia Smith

2026 Decisions

USDC for the Eastern District of Pennsylvania

Steven Helm V. Derek Slaughter

2026 Decisions

USDC for the Middle District of Pennsylvania

Essintial Enterprise Solutions Llc V. Sba

2026 Decisions

USDC for the Middle District of Pennsylvania

Spartan Daily, February 3, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 5

Settlement Status Report

Catholic Dioceses in Bankruptcy

No abstract provided.

Ai-Guided Hemodynamic Management In Non-Emergency Cardiac Surgery, James P. Warren, Maria Ledbetter

Group: Samford University Moffett & Sanders School of Nursing

This scholarly project examines the role of artificial intelligence (AI)–guided hemodynamic management in reducing intraoperative hypotension during non-emergent cardiac surgery. Intraoperative hypotension, defined as mean arterial pressure (MAP) below 65 mmHg, is a well-established risk factor for myocardial injury, acute kidney injury, and increased postoperative morbidity and mortality. Despite vigilant monitoring, traditional clinician-directed management remains largely reactive, intervening only after hypotension has occurred.

The project centers on a clinical case involving a 67-year-old male undergoing elective on-pump coronary artery bypass grafting, during which several transient hypotensive episodes occurred despite standard anesthetic care. These events served as a catalyst for an …

Education Accountability Regarding Oral Contraceptives And Sugammadex, Hallianne Hobson Herndon, Terri M. Cahoon

Group: Samford University Moffett & Sanders School of Nursing

Sugammadex is commonly used to antagonize neuromuscular blockade and has a clinically significant interaction with hormonal contraceptives by binding to plasma progesterone, reducing contraceptive efficacy and mimicking a missed dose. This case involved a healthy 21-year-old woman undergoing elective anterior cruciate ligament and medial collateral ligament repair whose only home medication was an oral contraceptive. She received midazolam prior to anesthesia assessment, limiting her ability to retain education, and counseling occurred at a suboptimal time without a support person present. Postoperative education was verbally relayed without standardized documentation or accountability. This project examined whether implementation of a standardized protocol regarding …

The Business Bankruptcy “Big 3” And The Unanticipated Benefits Of Subchapter V, Marshall V. Ringwood

BYU Law Review

The liberal bankruptcy venue rules in the United States have their defenders and advocates. Subchapter V of the Bankruptcy Code came into effect in 2020, justified as a bipartisan solution to a longstanding problem in corporate bankruptcy where restructuring under Chapter 11 was prohibitively expensive for small-business debtors. On June 21, 2024, Subchapter V’s extended debt limit of $7,500,000 in liabilities reverted back to a statutorily defined $3,024,725. In addition to the justifications offered by organizations such as the American Bankruptcy Institute (ABI) for both Subchapter V, generally, and a permanent increase to its debt limit, I argue that Subchapter …

Cheryl Peebles V. Chain Iq Americas Inc

2026 Decisions

USDC for the Eastern District of Pennsylvania

Steven Helm V. Derek Slaughter

2026 Decisions

USDC for the Middle District of Pennsylvania

Patient‐Specific Computational Flow Simulation Reveals Adverse Hemodynamic Factors Associated With Occlusion Of Directional Branches After Fenestrated‐Branched Endovascular Aneurysm Repair, Kenneth Tran, Jesse Chait, Emmanuel Tenorio, Weiguang Yang, Alison Marsden, Bernardo Mendes, Jason T. Lee, Gustavo S. Oderich

Mechanical Engineering Faculty Publications

Background: Fenestrated and branched endovascular aneurysm repair can be complicated by branch vessel occlusion in the absence of structural stenosis. We hypothesized that computational flow simulation could identify adverse hemodynamic features associated with postfenestrated and branched endovascular aneurysm repair branch occlusion.

Methods: Patients undergoing 4-vessel fenestrated and branched endovascular aneurysm repair for Extent II to IV thoracoabdominal aortic aneurysms were retrospectively reviewed. Branches that occluded without identifiable kinking or stenosis on computed tomography were included, along with an equal cohort of anatomy-matched patent controls. Patient-specific pulsatile rigid-wall simulations were performed using SimVascular with individualized geometries and boundary conditions. Abnormal time-averaged …

Novel Ankrd11 Mutation In Kbg Syndrome: A Diagnostic Triad Of Hearing Loss, Radiological Macrodontia And Artificial Intelligence-Assisted Facial Phenotyping, Azzeddine Laaraje, Khadija Belcadi Abassi, Mouna Lemaamer, Abdelilah Radi, Amale Hassani, Rachid Abilkassem

Sultan Qaboos University Medical Journal

KBG syndrome is a rare autosomal dominant disorder characterised by developmental delay, characteristic facial features, macrodontia and skeletal anomalies, caused by mutations in the ANKRD11 gene. We report a 5.5-year-old Moroccan boy who presented in 2022 to a tertiary military teaching hospital in Rabat, Morocco, with psychomotor delay, autistic traits, epilepsy, bilateral hearing loss with chronic otomastoiditis and radiologically-detected macrodontia before clinical eruption, in whom artificial intelligence-assisted facial phenotyping suggested the diagnosis, subsequently confirmed by identification of a novel nonsense mutation (c.1977C>G; p.Tyr659Ter). Multidisciplinary management including antiepileptic therapy, speech therapy and audiological follow-up resulted in satisfactory seizure control and …

Perspectives Of Efl Teachers Toward The Influence Of Ai Writing Tools On Students' Writing Content And Organization, Nguyen Huu Hoang

Higher Learning Research Communications

Objectives: This study investigated Vietnamese English as a foreign language (EFL) teachers’ perspectives on the influence of artificial intelligence (AI) writing tools on students’ writing content and organization, examining tool selection patterns and effectiveness relationships through a mixed-methods approach.

Methods: An exploratory sequential mixed-methods design was employed, combining semi-structured interviews and classroom observations with six EFL teachers, followed by a survey of 52 teachers from various Vietnamese universities. Data analysis integrated thematic analysis of qualitative data with correlation and regression analyses of survey responses to examine relationships between usage patterns, institutional factors, and effectiveness ratings.

Results: Teachers strategically combined multiple …

Solar-Xr: Comparing The Usability Of Touch And Raycast Gesture Input Techniques In An Educational Xr Application, James Clarke, Purity Biwott, Claudia Rivera, Marisa Llorens-Salvador, Mariana Rocha, Jack O’Neill, Tang Ming, Paul Doyle

Research Outputs: 2025-Present

This study investigates the comparative usability of two common bare-hand input techniques, touch and raycast, in the context of an educational extended reality (XR) application. An XR educational solar system application developed by the research team, Solar-XR, was used in the study. Thirty-four participants completed a series of tasks using both input methods in a within-subjects design. Usability was assessed using the validated VRSUQ questionnaire, performance was measured through task completion times, and user preferences were collected alongside qualitative feedback. Results showed that the touch input method was rated significantly more usable and was generally preferred by participants. While no …

Statistically Consistent And Novel Image Registration Methods For Various Transformations In Presence Of Zooming, Sujay Das

Doctoral Theses

In image processing literature, image registration is the process of spatially matching two or more images of the same scene or object obtained at various times, from different perspectives, or by separate sensors in order to simplify comparison, fusion, or analysis. Its purpose is to identify the spatial transformation that minimizes the differences between related characteristics or intensities in the reference and moved images. Image registration techniques find a wide range of applications in several imaging fields, namely, medical imaging, satellite imaging, fingerprint matching, remote sensing, and image comparison, to name a few. The growing popularity of this imaging field …

Response To Agency Comments Re: Comment Letter For The 2023 Butte Priority Soils Operable Unit (Bpsou) Groundwater Compliance Evaluation (Dated March 10, 2025) Received May 7, 2025, Josh Bryson

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Developing Deep Neural Network Based Brain Computational Models From Psychophysics Data Of Some Simple Perceptual Phenomena: Visual As Well As Auditory, Chandran Keerthi S

Doctoral Theses

The thesis, consisting of nine chapters, explores the methodology of building testable brain computational models using Deep Neural Networks (DNN), which are trained by psychophysics data. Psychophysics is the quantitative study of perception of physical stimuli. In psychophysics experiments, one or more parameters associated with the stimuli are changed, and the human subject’s responses to the stimuli are recorded. This thesis encompasses both experimental psychophysics works, as well as computational models of the phenomena involved. The contributory chapters of the thesis start in Chapter 2 with the perspective building of the novel methodology followed throughout this research involving psychophysics on …

Intercalated Bacterial Biofilms Are Intrinsic Internal Components Of Calcium-Based Kidney Stones, William C Schmidt, Henry L Schreiber, Rachael E S Hammann, Chloe L P Obernuefemann, Karla Bergeron, Aleksandra Klim, Daniel Wong, Kefu Du, Scott J Hultgren, Et Al.

2020-Current year OA Pubs

Calcium oxalate stones comprise greater than 70% of all kidney stones. In the current conceptual framework, the initial stone nidus is thought to include the aggregation of inorganic crystallites, the formation of which is favored by elevated concentrations of dissolved constituents. Here, we show that this highly prevalent stone type comprises a form of organic-inorganic polycrystalline biocomposite with integrated bacterial biofilms. Evidence from electron microscopy and fluorescence microscopy reveal the unanticipated internal structure of kidney stones from human patients, where bacterial biofilms are intercalated between polycrystalline mineral layers, even in stones identified as "noninfectious" clinically, including those in patients without …

Use Of Innovative Methods In The Creation Of Testing And Assessment Materials For Future Computer Science Teachers, Gulzhan Mazhibayeva, Serik Kenesbayev, Salamat Idrissov, Indira Salgozha, Zhanel Akhmetova

Higher Learning Research Communications

Objectives:This study aims to examine the effectiveness for future computer science teachers of employing innovative methods when creating innovative testing and assessment materials.

Methods:The methodology for this study involved analyzing survey data using statistical methods, such as descriptive analysis, correlation analysis, analysis of variance (ANOVA), regression, and factor analysis to evaluate the effectiveness of innovative methods in computer science education. Additionally, this study incorporated virtual labs, learning management systems, interactive quizzes, and artificial intelligence–based assessment tools to enhance learning outcomes and student engagement. We collected survey responses for this study from 56 student participants. We then developed a …

An Audit Of Endodontic Diagnostic Documentation Compliance Among Undergraduate Dental Students In A Uk Primary Care–Based Dental School., Araz Ahmed, Casper Jonker, Marina Bozic, Ewen Mccoll

Peninsula Dental School

Background: Erroneous pulpal and periapical diagnoses can lead to inappropriate treatment planning, unnecessary procedures, and compromised patient outcomes. While undergraduate endodontic education emphasises history taking, clinical testing and radiographic assessment, less is known about how consistently students document diagnostic conclusions in clinical records.Aim: To evaluate the completeness and compliance of endodontic diagnostic documentation among undergraduate dental students, benchmarked against British Endodontic Society (BES) and European Society of Endodontology (ESE) standards, and to explore trends across different stages of training.Methods: Records of 196 root canal treatments completed by Year 3–5 Bachelor of Dental Surgery students (2022–2024) were reviewed. Audit standards were …

Patient-Specific Computational Flow Simulation Reveals Adverse Hemodynamic Factors Associated With Occlusion Of Directional Branches After Fenestrated-Branched Endovascular Aneurysm Repair, Kenneth Tran, Jesse Chait, Emmanuel Tenorio, Weiguang Yang, Alison Marsden, Bernardo Mendes, Jason T Lee, Gustavo S Oderich

Faculty, Staff and Students Publications

Background: Fenestrated and branched endovascular aneurysm repair can be complicated by branch vessel occlusion in the absence of structural stenosis. We hypothesized that computational flow simulation could identify adverse hemodynamic features associated with postfenestrated and branched endovascular aneurysm repair branch occlusion.

Methods: Patients undergoing 4-vessel fenestrated and branched endovascular aneurysm repair for Extent II to IV thoracoabdominal aortic aneurysms were retrospectively reviewed. Branches that occluded without identifiable kinking or stenosis on computed tomography were included, along with an equal cohort of anatomy-matched patent controls. Patient-specific pulsatile rigid-wall simulations were performed using SimVascular with individualized geometries and boundary conditions. Abnormal time-averaged …

Rev-Erb-Alpha And -Beta Coordinately Regulate Astrocyte Reactivity And Proteostatic Function, Collin J Nadarajah, Michelle Y Li, Elsa I Quillin, Kevin Boyer, Julie M Dimitry, Yining Chen, Melvin W King, Ibrahim O Saliu, Jiyeon Lee, Patrick W Sheehan, Albert A Davis, Mitchell A Lazar, Guoyan Zhao, Erik S Musiek

2020-Current year OA Pubs

The molecular circadian clock is a ubiquitous transcriptional-translational feedback loop that regulates CNS function, glial responses, and neurodegenerative pathology. The nuclear receptors REV-ERB-α (

A Shareholder’S Guide To Blowing Up 100 Years Of Delaware Corporate Law: Intellectual Property And Corporate Governance After Delaware Senate Bill No. 313, Avery C. Hill

Journal of Intellectual Property Law

This note examines the intersection between shareholders agreements and intellectual property ownership in Delaware corporations after Delaware Senate Bill No. 313. Delaware corporate governance law has created extensive statutory and case law balancing the competing interests of corporate actors. The board of directors maintains an exclusive right to manage the affairs of a corporation, unless otherwise provided in the certificate of incorporation. Delaware law defers to director’s management authority through the business judgement rule, but fiduciary duties govern a director’s responsibly to shareholders. Shareholders maintain rights such as voting for the board of directors, receiving distributions, and selling shares, but …

The Transatlantic Clinical Trial Transparency Gap, Gabriela Lenarczyk

Journal of Intellectual Property Law

Clinical trial data occupy a contested space between private commercial assets and public goods. While the United States Food and Drug Administration (FDA) has historically shielded these data through expansive trade-secret interpretations, the European Union (EU) has adopted a more open disclosure regime. This Article compares the two regimes and traces how the EU’s two-decade journey toward transparency has become a key reference for researchers and advocates of open data-sharing.

Focusing on EU practices—targeted redactions, time-bound access, granular disclosure guidelines—the paper shows that U.S. objections to broader transparency often rest on overstated concerns about competitive harm. A Filspari (sparsentan) case …

The Free Content Illusion, Jonathan M. Barnett

Journal of Intellectual Property Law

Conventional scholarly wisdom tends to discount the importance of copyright as a tool for delivering remuneration to the artists that sustain the digital creative ecosystem or as an enabling mechanism that facilitates the licensing, distribution, and financing transactions that constitute the economic infrastructure of the media and entertainment industries. This position runs counter to the evolution of digital content markets, which have experienced renewed investment and growth concurrently with the development of technological tools that have enabled content owners to correct for the “copyright deficit,” regulate access, and extract payment from platforms and users. This result conforms to standard economic …

About The Author: Alison Hawthorne Deming

Creative Nonfiction Magazine

No abstract provided.

Solo, Susan L. Adkins

Creative Nonfiction Magazine

No abstract provided.

Love, War And Deer Hunting, John Hales

Creative Nonfiction Magazine

No abstract provided.