Digital Commons Network^™

Human-Ai Trust Misalignment Detection System: Behavioral Detection Of Over-Reliance On Automated Recommendations, Pranav Bhatnagar Mr

Defensive Publications Series

This disclosure presents a Human-AI Trust Misalignment Detection System designed to identify and mitigate conditions in which human operators develop excessive or unwarranted reliance on AI generated recommendations within decision workflows. As artificial intelligence systems become increasingly embedded in operational, analytical, and supervisory environments, a critical socio technical vulnerability emerges when human oversight weakens due to overconfidence in automated outputs. Traditional AI safety efforts have largely focused on model robustness, accuracy, and infrastructure security; however, comparatively little attention has been given to monitoring the human behavioral response to AI recommendations in real time. The proposed framework introduces a behavioral analytics …

The Confidence Trap Identifying When Ai Sounds Sure But Is Actually Wrong, Pranav Bhatnagar Mr

Defensive Publications Series

This disclosure introduces a Confidence–Reliability Divergence Detection framework designed to identify conditions in which artificial intelligence systems express high apparent certainty while underlying predictive reliability degrades. As modern AI models increasingly expose probability scores, verbal certainty cues, or calibrated confidence metrics, human operators and downstream systems frequently treat these signals as reliable proxies for correctness. However, real-world deployments demonstrate that model confidence can become systematically misaligned with true performance under conditions such as distribution shift, adversarial prompting, long-context reasoning saturation, data sparsity, or environmental volatility. This divergence creates a subtle but high-impact failure mode in which AI outputs appear authoritative …

2026 February 23 - Faculty Senate Agenda And Minutes, Faculty Senate, East Tennessee State University

Faculty Senate Agendas and Minutes

No abstract provided.

A Capability Maturity Model For Artificial Intelligence Integration In Supply Chain Management, Lordt Becklines

Dissertations

Artificial Intelligence (AI) is transforming Supply Chain Management (SCM), yet many organizations struggle to assess their readiness for AI adoption and to understand how AI capabilities develop across maturity stages. This dissertation addresses this gap by developing a Capability Maturity Model (CMM) for AI integration in SCM, grounded in Organizational Information Processing Theory (OIPT), the Resource-Based View, and related capability frameworks. The model provides a structured approach for evaluating an organization's information-processing requirements, resource configurations, and alignment needed for effective AI-enabled supply chain operations.

Using a design science research approach, the AI-SCM CMM and its associated assessment instrument were derived …

Analysis Of H.R.1129 Tax Relief Unleashed For Seniors By Trump Act, Shuang Zhang

The Contemporary Tax Journal

No abstract provided.

The Third Annual Blockchain Tax Conference On January 30, 2026: Digital Assets And Its Numerous Instruments Governing Formation And Operation, Joyce Yu

The Contemporary Tax Journal

No abstract provided.

Non-Glycosylated, Legumain-Cleavable Isacs Drive Potent Anti-Tumor Immunotherapy Via A Bystander Effect, Anqi Zhang, Mohan Reddy Mullapudi, Lina Wu, Michele Yi, Mohammad Asikur Rahman, Aiman A. Yaseen, H Kayla Zhong, Tracy A. Brooks, L Nathan Tumey

Pharmacy Faculty Scholarship

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal form of pancreatic cancer, with poor prognosis driven by late diagnosis, therapeutic resistance, and an immunosuppressive tumor microenvironment. Interactions between tumor cells and immune cells promote immune evasion and tumor progression, limiting the efficacy of immune checkpoint blockade and other immunotherapies. Given the high expression of trophoblast cell surface antigen 2 (TROP2) in PDAC, we developed a TROP2-targeted Toll-like receptor 7 (TLR7) agonist (E104) designed for selective accumulation within the tumor microenvironment to activate antitumor immunity. Although antibody bioactivity is traditionally linked to Fcγ receptor (FcγR) engagement and recruitment of effector cells, …

The Third Annual Blockchain Tax Conference On January 30, 2026: Dealing With The 2025 Forms 1099-Da, Leah Upson

The Contemporary Tax Journal

No abstract provided.

Dose-Dependent Ifn Programs In Myeloid Cells After Mrna And Adenovirus Covid-19 Vaccination., Giray N Eryilmaz, Yilmaz Yucehan Yazici, Radu Marches, Eleni P Mimitou, Lisa Kenyon-Pesce, Kim Handrejk, Sonia Jangra, Michael Schotsaert, Adolfo García-Sastre, George A Kuchel, Jacques Banchereau, Duygu Ucar

Faculty Research 2026

BACKGROUND. The SARS-CoV-2 pandemic provided a rare opportunity to study how human immune responses develop to a novel viral antigen delivered through different vaccine platforms. However, to date, no study has directly compared immune responses to all 3 FDA-approved COVID-19 vaccines at single-cell multiomic resolution.

METHODS. We longitudinally profiled SARS-CoV-2–naive adults (n = 31) vaccinated with BNT162b2, mRNA-1273, or Ad26.COV2.S, integrating plasma cytokines, antibody titers, and single-cell multiomic data (DOGMA-Seq).

RESULTS. We discovered a distinct, transient IFN program termed ISG-dim, which emerged specifically 1–2 days after the first mRNA dose in approximately 10% of myeloid cells. This state was …

Structure–Activity Modeling And Hybrid Machine Learning-Based Prediction Of Bioactivity In Pyrazole Derivatives For Drug Discovery Applications, Kader Şahi̇n, Serhat Kiliçarslan, Serdar Durdaği, Emi̇n Saripinar

Turkish Journal of Biology

Background/aim: Pyrazole derivatives are of growing interest due to their diverse pharmacological activities. However, their biological activity is often highly sensitive to subtle structural modifications. Existing quantitative structure–activity relationships (QSAR) approaches frequently fail to capture the conformational flexibility and nonlinear structure–activity relationships (SAR) of such heterocyclic scaffolds, creating a gap in the accurate prediction of their biological profiles. Therefore, there is a strong need for more robust and predictive computational frameworks. This study addresses this gap by integrating four-dimensional (4D)-QSAR descriptors with hybrid machine learning (ML) techniques to improve predictive accuracy and provide a more reliable tool for structure-based drug …

February 23 Elections, Census & Redistricting Update, Jeffrey M. Wice

Elections, Census & Redistricting Updates

No abstract provided.

Intraspecific Meristic Variation In Gambusia Holbrooki From The Middle East And Its Implications For Stock Structure And Taxonomic Status, Fatema A. Al Fatle, Ana L. Ibaňez, Laith A. Jawad

Baghdad Science Journal

An analysis was conducted on the variation in the counts of seven meristic traits of the eastern mosquito fish, Gambusia holbrooki, using samples collected from ten different sites in the Middle East. These sites are located along the Tigris, Euphrates, and Shatt al-Arab Rivers, spanning across Iraq, Iran,Türkiye, and Syria. The study revealed a northward increase in the average values of these meristic traits, with the highest recorded in Türkiye and the lowest in the southern region of Iraq. The statistical analysis using Boxplots demonstrated that the seven meristic features were distinct across different rivers, with no overlap observed. …

Green Synthesis And Characterization Of Prepared Copper Iodide (Cui) Nanoparticles Using Red Cabbage Extract, A. S. Abd-Alsada, Zainab J. Shanan, Aqel Mashot Jafar

Baghdad Science Journal

Copper iodide nanoparticles, CuI NPs, are one of the promising materials for use in many electronic applications. In this work, transparent CuI nanoparticles were prepared by the green force synthesis, which was done by red cabbage extract used not only as a reduction but also as a capping agent to reduce the toxicity in the preparation of CuI nanostructures. The structural properties were investigated by the X-ray diffraction analysis technique, XRD. The X-ray analysis shows the structure has a polycrystalline nature with a cubic phase and appears to have a preferential orientation direction along the (111) plane. Atomic force microscopy …

Dose-Dependent Ifn Programs In Myeloid Cells After Mrna And Adenovirus Covid-19 Vaccination., Giray N Eryilmaz, Yilmaz Yucehan Yazici, Radu Marches, Eleni P Mimitou, Lisa Kenyon-Pesce, Kim Handrejk, Sonia Jangra, Michael Schotsaert, Adolfo García-Sastre, George A Kuchel, Jacques Banchereau, Duygu Ucar

Faculty Research 2026

BACKGROUNDThe SARS-CoV-2 pandemic provided a rare opportunity to study how human immune responses develop to a novel viral antigen delivered through different vaccine platforms. However, to date, no study has directly compared immune responses to all 3 FDA-approved COVID-19 vaccines at single-cell multiomic resolution.METHODSWe longitudinally profiled SARS-CoV-2-naive adults (n = 31) vaccinated with BNT162b2, mRNA-1273, or Ad26.COV2.S, integrating plasma cytokines, antibody titers, and single-cell multiomic data (DOGMA-Seq).RESULTSWe discovered a distinct, transient IFN program termed ISG-dim, which emerged specifically 1-2 days after the first mRNA dose in approximately 10% of myeloid cells. This state was characterized by ISGF3 complex activation and …

Investigation Of Antimicrobial Synergism Of Actinomycin Derivatives From Streptomyces Parvus 35m1 Against Escherichia Coli Atcc 25922, Özge Can, Mustafa Ünver Kurt, Meli̇s Küçüksolak, Ataç Uzel, Erdal Bedi̇r

Turkish Journal of Biology

Background/aim: Limited drug development and increased antibiotic tolerance among Gram-negative bacteria have led researchers to consider combination therapy. Actinomycin derivatives, particularly actinomycin D, exhibit a wide range of bioactivities, including antibacterial effects. However, actinomycin D is less effective against Gram-negative pathogens. Therefore, it is essential to demonstrate the synergy of actinomycin D and its derivatives with clinically known antibiotics against Escherichia coli ATCC 25922 and investigate the effects on cellular morphology.

Materials and methods: Streptomyces parvus 35M1 isolated from coastal sediment in İzmir/Türkiye was identified via genome sequencing. Large-scale (30 L) fermentation followed by chromatographic purification yielded compounds 1 (actinomycin …

Digital Competence Of Primary School Teachers In Andalusia (Spain): A Multidimensional Analysis Based On Self-Perceptions, Francisco Ábalos-Aguilera, Luis M. Romero-Rodríguez, Bárbara Mercedes Castillo Abdul Hadi

Artículos científicos

This study analyzes the self-perception of digital teaching competence (DTC) among primary education teachers in Andalusia, using an instrument based on the European DigCompEdu framework. Data were collected through a self-administered online questionnaire applied to a sample of 416 primary education teachers working in Andalusia. The study employed a mixed-methods design, combining quantitative analyses (descriptive, correlational, and comparative) with qualitative analysis of open-ended responses. Employing a mixed-methods approach, the research assesses teachers’ competence levels and examines differences according to professional experience, school ownership, teaching specialization, and territorial distribution. Results indicate that most teachers perceive themselves at intermediate levels of digital …

The Echo: February 23, 2026, Taylor University

2025-2026 (Volume 113)

No abstract provided.

Addressing Faculty Gaps In The Psychiatric Mental Health Nurse Practitioner Program, Shea Brock

Doctor of Nursing Practice Projects

Graduate nursing programs increasingly rely on adjunct faculty to sustain enrollment growth; however, inconsistent onboarding processes may contribute to variability in faculty preparedness and job satisfaction. The purpose of this quality improvement project was to implement a standardized adjunct faculty education program and evaluate its impact on adjunct faculty knowledge and job satisfaction within an online Psychiatric–Mental Health Nurse Practitioner (PMHNP) program. A quantitative, quasi-experimental one-group pre–post design was utilized. Six adjunct faculty members (n = 6) completed a 10-item EXXAT Knowledge Survey and a 10-item Faculty Satisfaction Survey before and after participation in a structured one-hour education session focused …

Breast Cancer Mortality In Memphis: A Holistic Approach - Research Findings And Strategies For Improved Outcomes In Segregated Communities, The Benjamin L. Hooks Institute For Social Change

The Hooks Institute Policy Papers

The Benjamin L. Hooks Institute for Social Change (Hooks Institute) is pleased to present its tenth edition of the policy papers, which focuses on breast health outcomes for women living in racially segregated commu-nities. The research that informed the articles in this publication, as well as this volume of the policy papers itself, was funded by a 2022 grant from the National Institutes of Health (NIH). The grant was awarded to a team of researchers that included Shelley White-Means, PhD (Principal Investigator); Arash Shaban-Nejad, MSc, MPH, PhD and Minghui Li, MSc, PhD (Co-Investigators) at University of Tennessee Health Science Cen-ter …

Tree Diversity Is Changing Across Tropical Andean And Amazonian Forests In Response To Global Change, B. Fadrique, F. Costa, F. Cuesta, G. Arellano, L. Cayuela, T. R. Baker, F. C. Draper, A. Esquivel-Muelbert, H. Ter Steege, M. Bauters, J. Aguirre-Gutiérrez, Z. Aguirre-Mendoza, M. N. Alexiades, E. Alvarez-Davila, E. Arets, E. Ayala, C. G.A. Aymard, F. Baccaro, S. Báez, C. Baraloto, R. I. Barbosa, P. Barbosa Camargo, J. Barlow, P. E. Barni, J. Barroso, M. Benchimol, A. C. Bennett, E. Berenguer, L. Blanc, D. Bonal

School of Geography, Earth and Environmental Sciences

Climate and atmospheric changes are impacting forest function and structure worldwide, but their effects on tropical forest diversity are unclear. Nowhere is the scientific challenge greater than in the Andes and the Amazon, which together include the world’s most diverse forests. Here, using 406 permanent plots spanning four decades of intact lowland and montane forest dynamics, we test for long-term change in species richness and assess the influence of climate and other variables. We show that, at a continental scale, species richness appears stable, but this masks substantial regional variation. Species richness increased in Northern Andean and Western Amazon plots, …

Positional Differences In Internal And External Match-Play Loads Among Njcaa Division Ii Women's Soccer Players, Shannon Baisden

Doctorate in Kinesiology

This study quantified and compared the internal and external match-play demands of female community college soccer players by position during competitive match play. Using a retrospective observational design, GPS- and heart-rate–derived data were analyzed across eight regular-season matches from one NJCAA Division II women's soccer team. Nineteen outfield players were classified as defenders, midfielders, or forwards. Internal load was assessed using heart-rate metrics and time spent in intensity zones, while external load was measured using total distance and proprietary workload metrics. Linear mixed-effects models were employed to evaluate positional differences while accounting for repeated measures. Results revealed clear positional trends …

Short-Term Spark Or Long-Term Flame? Sustaining Academic Psychiatric Departments, Rohit Shankar, Richard Laugharne, Derek K. Tracy, Dinesh Bhugra

Peninsula Medical School

SummaryOver the past two decades, the number of academic psychiatrists in the UK has declined by more than a third, despite an expansion in medical schools and growth in most other medical academic specialties. Drawing on direct experience of establishing a new academic unit, we argue that the long-term sustainability of academic psychiatry departments is critical for service quality, innovation and talent development. This paper outlines the structural, cultural and strategic factors needed to create academic units that endure and flourish beyond individual careers, enabling better integration of research and clinical practice.

The 41st Annual Tei – Sjsu High Tech Tax Institute Conference On November 3-4, 2025: Tax Issues In International Ip Transactions, Sandhya Dharani

The Contemporary Tax Journal

No abstract provided.

Innovative Approaches For Lung Cancer Screening And Interception, Jianjun Zhang, Matthew D Park, Tej Pandya, Elaine Shum, Jia Wu, Simon Heeke, Ramin Salehi-Rad, Thomas U Marron, Zhubo Wei, Hui Li, Torsten G Blum, John V Heymach, Steven M Dubinett, Pan-Chyr Yang, Charles Swanton, Miriam Merad

Faculty, Staff and Student Publications

Lung cancer remains the leading cause of cancer-related deaths worldwide, partly because many patients are diagnosed at late stages, highlighting the urgent need for effective early detection and intervention strategies. Low-dose computed tomography (LDCT)-based screening reduces lung cancer mortality in high-risk populations defined by age and smoking history; however, the uptake of LDCT remains low among eligible individuals. Compounding this issue, modelling studies estimate that nearly half of lung cancers occur in individuals who do not meet eligibility criteria for LDCT-based lung cancer screening under current guidelines. Moreover, LDCT-based screening has inherent limitations, including a high rate of false-positive results …

Economic Evaluation Of Perioperative Pembrolizumab Plus Standard Of Care As Treatment For Resectable Locally Advanced Head And Neck Squamous Cell Carcinoma In The United States, Feng Qian, Arielle G Bensimon, Anjela Tzontcheva, Kimberly Benjamin, Ravindra Uppaluri, Douglas Adkins, Geoffrey Johnson, Catherine Fernan, Dandan Zheng, Yuexin Tang, Biruk Chafamo, Dominic Muston

2020-Current year OA Pubs

AIMS: In the phase 3 KEYNOTE-689 trial (NCT03765918) among patients with resectable locally advanced head and neck squamous cell carcinoma (LA HNSCC), perioperative pembrolizumab (pembrolizumab before surgery, then continued with standard-of-care [SOC] radiotherapy +/- cisplatin after surgery followed by pembrolizumab alone) significantly prolonged event-free survival vs. SOC alone, both in the intention-to-treat population and PD-L1 combined positive score (CPS) ≥1 subgroup. Perioperative pembrolizumab + SOC received Food and Drug Administration approval in June 2025 for resectable LA HNSCC expressing PD-L1 (CPS ≥ 1). The present study evaluated the cost-effectiveness of perioperative pembrolizumab + SOC versus SOC in this indication, from …

Exploring The Role Of Higher Education Leaders In Quality Culture Development: A Mixed Methods Study, Eshetu Mandefro, Tesfaye Semela, Ashebir Bezabhi

Higher Learning Research Communications

Objectives: In higher education institutions (HEIs), building a strong quality culture (QC) is essential to ensure the quality of education provided. QC integrates organizational, managerial, and psychological elements that shape how quality is understood and improved in HEIs. This study explores how leaders at the departmental and faculty levels navigate and contribute to quality culture development (QCD).

Methods: We employed a sequential explanatory mixed-methods design. A total of 1,029 academics completed questionnaires, and 33 leaders at the departmental and faculty levels were interviewed at three public universities in Ethiopia.

Results: The findings reveal that leadership roles at the departmental and …

Discrete Quantization On Spherical Geometries: Explicit Models, Computations, And Didactic Exposition, Mrinal Kanti Roychowdhury

School of Mathematical & Statistical Sciences Faculty Publications

This article presents a comprehensive and analytically explicit study of optimal discrete quantization on spherical geometries equipped with the geodesic metric. Focusing on highly symmetric configurations on the unit sphere 𝕊2, we investigate three explicit models of discrete uniform distributions and derive closed-form expressions for their optimal quantizers and corresponding mean square quantization errors. (I) For N equally spaced points on the equator, we obtain exact error formulas for both divisible and non-divisible cases 𝑛 ∤𝑁, demonstrating that optimal Voronoi cells form contiguous arcs with midpoint representatives. (II) For two antipodally symmetric small circles at latitudes ±𝜙0, each with M …

Raman Spectroscopic Monitoring Of Multiproduct Chemical Reaction Kinetics; The Case Of Ester Hydrolysis, Muhammed Kashif, Mark E. Keating, Hugh J. Byrne

Research Outputs: 2025-Present

Seeded MCR-ALS with optimized seeding weights enhances spectral unmixing by mitigating rank deficiency issues, yielding reliable concentration profiles, reducing residual errors and enhancing kinetic interpretation.

Chimes: February 23, 2026, Calvin University

Chimes

A vibrant tapestry of cultures: Rangeela celebrates 30 years by Ava Roush & Ellerry Johnson

Puentes: Students building bridges amidst immigration concerns by Jorie Cho

Late Night Era's Concert: The end of an era by Ashley Hamons

Cave Night kickoff hosts local artists by Alec DeYoung

Composting streamlined and expanded to all underclassmen dorms by McKenna Wilkinson

Let's talk about sec: Calvin sexuality series confronts purity culture by Sarah Sparling

Scaling rock walls and studying Scripture by Ella Vanden Berg

Showpower: A New Paradigm For Community Engagement, Sean Green

Community Engagement

For decades, the dominant paradigm in community engagement, education, and social work has relied heavily on the concept of "empowerment" to address the systemic gaps hindering marginalized populations. However, the etymological and practical applications of empowerment have increasingly devolved into a paternalistic, deficit-based model, implying a directional transfer of authority from a privileged institution to a subjugated community. As recent scholarship confirms, historically marginalized groups—such as first-generation and low-income students—continue to face persistent structural barriers despite decades of these traditional institutional interventions (López et al., 2023). This white paper formally introduces a novel theoretical framework, lexicon, and operational mindset: Showpower. …