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Articles 17401 - 17430 of 1326786
Full-Text Articles in Entire DC Network
When Should The Legal System Help Redistribute Income?, Jacob Goldin, Zachary Liscow
When Should The Legal System Help Redistribute Income?, Jacob Goldin, Zachary Liscow
University of Chicago Law Review
Should legal rules be designed exclusively based on efficiency considerations, or should they also attempt to promote an equitable distribution of social resources? The answer traditionally associated with scholarship in law and economics is that they should focus only on efficiency. Even for a society that cares about achieving an equitable distribution of resources by income, the argument goes, it is generally better to adopt legal rules based exclusively on efficiency considerations while relying on the income tax and transfer system to promote distributional goals.
However, even proponents of the claim that social welfare is best promoted through the adoption …
International Notes, Arthur S. Leonard
Trademasks, Matthew Sipe
Pocket Arbitration!, D. Mclean Campbell
Pocket Arbitration!, D. Mclean Campbell
North Carolina Law Review
No abstract provided.
Transcatheter Aortic Valve Replacement In Systemic Sclerosis: A Case Series And Review Of Short- And Long-Term Outcomes, Chris T. Derk, Ahmadreza Badali, Esra Mehmetoglu, Anvitha Mummadisetty, Amit Syal, Konstantinos Parperis
Transcatheter Aortic Valve Replacement In Systemic Sclerosis: A Case Series And Review Of Short- And Long-Term Outcomes, Chris T. Derk, Ahmadreza Badali, Esra Mehmetoglu, Anvitha Mummadisetty, Amit Syal, Konstantinos Parperis
Student Papers, Posters & Projects
Objectives: A higher frequency of valvular heart disease is seen among Systemic Sclerosis (SSc) patients. Advanced aortic valve stenosis leads to significant morbidity in these patients with multiple other comorbidities. In this study, we aim to define the short- and long-term outcomes of transcatheter aortic valve replacement (TAVR) procedures in SSc patients. Methods: We undertook a retrospective chart review of all patients with SSc who underwent a TAVR procedure at our institution over a defined 11-year period. Demographics as well as short- and long-term outcomes were identified. Results: Fourteen SSc patients underwent a TAVR procedure between 2012 and 2023. They …
Contagious Discrimination: Why Race-Blind Justice In Courtrooms Is Not Enough, Yijia Lu, Murat C. Mungan
Contagious Discrimination: Why Race-Blind Justice In Courtrooms Is Not Enough, Yijia Lu, Murat C. Mungan
Faculty Scholarship
Existing theories of discrimination focus on discrimination at the individual, societal, or organizational level. We highlight the importance of the dynamic relationship between different institutional actors who jointly give rise to discriminatory outcomes. This reveals that discrimination can be contagious: discrimination that would otherwise not occur at one institutional level can arise due to discrimination at another institutional level. Therefore, discrimination by some actors can trickle down and create disparate impacts in processes that would otherwise be free of discrimination. This phenomenon, which we term “contagious discrimination,” can manifest itself in various settings such as employment and commercial trade negotiations. …
Chicana Professionalism: Embracing Greñas, Glitter & Boots, Luz E. Herrera
Chicana Professionalism: Embracing Greñas, Glitter & Boots, Luz E. Herrera
Faculty Scholarship
The current political moment, where immigrant identity is scapegoated and academic freedom is threatened, requires an affirmation of personal identity, a recognition of personal struggle, and a celebration of resilience. This Essay embraces the ideas that professional identity development is temporal and that the current conceptualization of professionalism requires embarking on a reflection journey that addresses the dissonance between personal conscience and professional duty. Part I briefly revisits the work of Professor Margaret E. Montoya, one of the first Chicana law professors that describes the formation of her professional identity as a law student. It explores the status of Latinas …
The Lost Origins Of Antitrust, William Magnuson
The Lost Origins Of Antitrust, William Magnuson
Faculty Scholarship
Over the last decade, the once-sleepy field of antitrust has suddenly sprung to the forefront of public attention. The digitalization of the economy, the expansion of Big Tech, and the rise of platform monopolies have all raised deep questions about the nature of corporate power and law’s capacity to constrain it. Some scholars have argued that antitrust enforcement must be reinvigorated in substance and broadened in scope in order to combat rapidly rising economic inequality. Others have argued that antitrust law is ill-equipped to address these broad moral issues and instead must be re-focused on its traditional principles of consumer …
Deep Learning Approaches For Anti-Money Laundering On Mobile Transactions: Review, Framework, And Directions, Jiani Fan, Lwin Khin Shar, Ruichen Zhang, Ziyao Liu, Wenzhuo Yang, Dusit Niyato, Kwok-Yan Lam
Deep Learning Approaches For Anti-Money Laundering On Mobile Transactions: Review, Framework, And Directions, Jiani Fan, Lwin Khin Shar, Ruichen Zhang, Ziyao Liu, Wenzhuo Yang, Dusit Niyato, Kwok-Yan Lam
Research Collection School Of Computing and Information Systems
Money laundering is a financial crime that obscures the origin of illicit funds, necessitating the development and enforcement of anti-money laundering (AML) policies by governments and organizations. The proliferation of mobile payment platforms and smart IoT devices has significantly complicated AML investigations. As payment networks become more interconnected, there is an increasing need for efficient real-time detection to process large volumes of transaction data on heterogeneous payment systems by different operators such as digital currencies, cryptocurrencies, and account-based payments. Most of these mobile payment networks are supported by connected devices, many of which are considered loT devices in the FinTech …
Dyadic Respiratory Sinus Arrhythmia Outcomes For Mothers And Their Children: Long-Term Follow-Up Of A Randomized Controlled Trial Of Brief Parenting Interventions, Abigail Sullivan, Sophia Eisenberg Garcia, Maria Kinsey, Komal Brown, Rong Bai, Melissa Mcternan, Seth J. Scholer, Ron Prinz, Julia Fleckman, Stacy Drury, Catherine A. Taylor
Dyadic Respiratory Sinus Arrhythmia Outcomes For Mothers And Their Children: Long-Term Follow-Up Of A Randomized Controlled Trial Of Brief Parenting Interventions, Abigail Sullivan, Sophia Eisenberg Garcia, Maria Kinsey, Komal Brown, Rong Bai, Melissa Mcternan, Seth J. Scholer, Ron Prinz, Julia Fleckman, Stacy Drury, Catherine A. Taylor
Student Publications [Scholarly]
This study was part of a longitudinal follow-up of a 3-armed randomized controlled trial designed to test the effects of two brief parenting interventions, Play Nicely (PN) and Triple P-Level 2 (TP2), to a usual care control on parenting outcomes. Female caregivers with an identified index child (Mage = 3.7 years, standard deviation [SD] = 1.7) were recruited through women, infants, and children (WIC) clinics in the greater New Orleans region. At a long-term (Myears = 5 years, SD = 0.9) follow-up assessment, respiratory sinus arrhythmia (RSA) was assessed for a subset of these mother–child dyads during three dyadic interaction …
Stepreg: A Comprehensive And Intuitive R Package For Stepwise Regression Analysis, Junhui Li, Kai Hu, Xiaohuan Lu, Cesar B. Sotelo, Sushmita Nayak, Michael A. Lodato, Wenxin Liu, Lihua Julie Zhu
Stepreg: A Comprehensive And Intuitive R Package For Stepwise Regression Analysis, Junhui Li, Kai Hu, Xiaohuan Lu, Cesar B. Sotelo, Sushmita Nayak, Michael A. Lodato, Wenxin Liu, Lihua Julie Zhu
Student Publications [Scholarly]
Stepwise regression remains widely used for model selection, yet the field lacks a comprehensive, well-documented tool that supports diverse model families and selection strategies, implements multiple information criteria, and addresses overfitting and post-selection inference. We present StepReg, an R package that unifies stepwise selection across linear, generalized linear (e.g., logistic, Poisson, Gamma, negative binomial), and Cox models, supporting forward, backward, bidirectional, and best-subset search under various information criteria. StepReg also supports multivariate multiple linear stepwise regression, enabling simultaneous modeling of multiple dependent variables. Users can explore multiple strategies and information criteria within a single function call, and optionally combine them …
Point-Of-Care Vision Correction: A Pilot Study Of Mobile Refractive Screening And Same Day Glasses Distribution In A Street Medicine Program, Tejasvi Paturu, Veena Jajoo, Emily Coughlin, Rebecca Lipscomb, Seth A. Campbell Pa-C
Point-Of-Care Vision Correction: A Pilot Study Of Mobile Refractive Screening And Same Day Glasses Distribution In A Street Medicine Program, Tejasvi Paturu, Veena Jajoo, Emily Coughlin, Rebecca Lipscomb, Seth A. Campbell Pa-C
USF-LVHN SELECT
No abstract provided.
Molecular Gas And Star Formation In Central Rings Across Nearby Galaxies, Damian R. Gleis, Sophia K. Stuber, Eva Schinnerer, Justus Neumann, Sharon E. Meidt, Miguel Querejeta, Eric Emsellem, Adam K. Leroy, Ashley T. Barnes, Frank Bigiel, Charlie Burton, Mélanie Chevance, Daniel A. Dale, Kathryn Grasha, Ralf S. Klessen, Rebecca C. Levy, Lukas Neumann, Hsi An Pan, Marina Ruiz-García, Mattia C. Sormani, Jiayi Sun, Yu Hsuan Teng, Thomas G. Williams
Molecular Gas And Star Formation In Central Rings Across Nearby Galaxies, Damian R. Gleis, Sophia K. Stuber, Eva Schinnerer, Justus Neumann, Sharon E. Meidt, Miguel Querejeta, Eric Emsellem, Adam K. Leroy, Ashley T. Barnes, Frank Bigiel, Charlie Burton, Mélanie Chevance, Daniel A. Dale, Kathryn Grasha, Ralf S. Klessen, Rebecca C. Levy, Lukas Neumann, Hsi An Pan, Marina Ruiz-García, Mattia C. Sormani, Jiayi Sun, Yu Hsuan Teng, Thomas G. Williams
Physics and Astronomy Faculty Publications
Context. Nearby galaxies exhibit a variety of structures, including so-called central or (circum-)nuclear rings that are similar to the Milky Way (MW) Central Molecular Zone (CMZ). These rings are common in barred galaxies and can be gas-rich and highly star-forming. Aims. We aim to study the molecular gas content and star formation rate of central rings within nearby galaxies and link them to global galaxy properties, especially the bar morphology. Methods. We utilized 1″(≲100 pc) resolution CO(2–1) observations from the PHANGS-ALMA survey, visually identifying 20 central rings and determine their properties. For 14 of these rings, MUSE observations tracing star …
Regulatory Cost Of Production In Napa County Vineyards, Lynn Hamilton, Michael Mccullough
Regulatory Cost Of Production In Napa County Vineyards, Lynn Hamilton, Michael Mccullough
Agribusiness
Regulatory costs are an increasing concern for California growers. Recent studies in Salinas Valley lettuce and San Joaquin Valley fruit, vegetable and row crops show that regulatory costs are growing at a much faster rate than costs of production. Napa County Farm Bureau contacted Cal Poly to conduct a case study of regulations accruing to Napa Valley vineyards. We interviewed one large (1000-acre) and one small (200-acre) vineyard in 2025 and documented the costs of complying with regulations in the following categories:
• Education and Training for Regulatory Compliance
• Air Quality
• Water Quality
• Surface and Groundwater Regulations …
Adam N. Steinman, Adam N. Steinman
Evidence And Assessing Verbatim Transcription Quality Of Black English And Standard American English, L. Alexander Walker Iii
Evidence And Assessing Verbatim Transcription Quality Of Black English And Standard American English, L. Alexander Walker Iii
Faculty Scholarship
This chapter explores the accuracy of private transcription services when transcribing Black English and Standard American English. Courts and lawyers in the US regularly rely on transcripts from such services, but third-party verification of their accuracy, especially with respect to their quality when faced with nonstandard language varieties, is lacking. This study draws on experimental methods to contrast the quality of transcription services offered by transcribers and AI route. The quantitative results show that transcription by humans and AI resulted in more mistakes when transcribing Black English than when transcribing Standard American English. Furthermore, a qualitative analysis reveals that these …
Post-Chevron Deference In Asylum Proceedings, Shawn E. Fields
Post-Chevron Deference In Asylum Proceedings, Shawn E. Fields
Cardozo Law Review
The Supreme Court held for four decades that Chevron deference should apply in all immigration proceedings. How, then, will asylum proceedings change in a post-Chevron world? When, and under what circumstances, will courts continue to defer to the findings of immigration judges and the Board of Immigration Appeals (BIA)? And why does it matter? This Article answers those questions.
These issues require urgent examination for three reasons. First, they directly confront an issue pending before the U.S. Supreme Court in Urias-Orellana v. Bondi: Without the protection of Chevron insulating BIA decisions from meaningful judicial review, can certain legal questions like …
Evaluation Of Pulse Oximetry Alarm Fatigue And The Impact Of Spo2 Thresholds On Clinical Workflow: A Prospective Observational Study In A Kenyan Neonatal Unit, Bazil Masabo, Augustine Waswa, Jesse Coleman, Morris Ogero, Grace Irimu, Dorothy Chomba, Millicent Parsimei, Cynthia Shitote, Ferdinand Okwaro, William Macharia
Evaluation Of Pulse Oximetry Alarm Fatigue And The Impact Of Spo2 Thresholds On Clinical Workflow: A Prospective Observational Study In A Kenyan Neonatal Unit, Bazil Masabo, Augustine Waswa, Jesse Coleman, Morris Ogero, Grace Irimu, Dorothy Chomba, Millicent Parsimei, Cynthia Shitote, Ferdinand Okwaro, William Macharia
Paediatrics and Child Health, East Africa
Introduction: Effective pulse oximetry monitoring in a newborn unit requires clinician action. However, if thresholds are not adapted to each neonate, frequent alarms cause alarm fatigue, which impacts the quality of patient monitoring, staff workload and clinical workflow.
Methods: We conducted an observational study from October 2021 to December 2022 in a Kenyan newborn unit which enrolled neonates through convenience sampling. Data were analysed in R using default thresholds of 85% to 96% for SpO2 and 90 to 200 bpm for PR.
Results: Among the 49 neonates enrolled, median hourly alarms per patient were 12 visual and …
Caregiver Assessment Of Executive Function Deficits Among Hiv-Infected And Hiv-Exposed Uninfected Preschool Children In Kenya, Antipa Sigilai, Moses Nyongesa, Amin Hassan, Janet Thoya, Rachel Odhiambo, K. Katana, Beatrice Kabunda, Grace Bomu, Charles Newton, Amina Abubakar
Caregiver Assessment Of Executive Function Deficits Among Hiv-Infected And Hiv-Exposed Uninfected Preschool Children In Kenya, Antipa Sigilai, Moses Nyongesa, Amin Hassan, Janet Thoya, Rachel Odhiambo, K. Katana, Beatrice Kabunda, Grace Bomu, Charles Newton, Amina Abubakar
Institute for Human Development, East Africa
Background: This study examined caregiver assessment of executive functioning (EF) in perinatally HIV-infected (PHIV) and perinatally HIV-exposed but uninfected (PHEU) Kenyan children, and explored the extent to which various biopsychosocial factors influence EF outcomes.
Methods: Children aged 3–5 years that were PHIV (n = 43), PHEU (n = 52), or HIV-unexposed uninfected (HUU, n = 58) and their caregivers were enrolled in this study. EF was measured using the Childhood Executive Functioning Inventory. Caregivers’ common mental disorders (CMDs) and parenting behaviour were evaluated using the Shona Symptoms Questionnaire (SSQ) and a parenting behaviour scale, respectively. We used analyses …
Exploring Clinician Decision-Making Behind Preoperative Ekg Orders In Primary Care, Joon Cha, Katerina C. Valavanis Md, Grant M. Greenberg M.D., M.H.S.A., M.A.
Exploring Clinician Decision-Making Behind Preoperative Ekg Orders In Primary Care, Joon Cha, Katerina C. Valavanis Md, Grant M. Greenberg M.D., M.H.S.A., M.A.
USF-LVHN SELECT
No abstract provided.
Evaluation Of Publicly Available Maize Germplasm Adaptation To Environments In Nebraska, Garrett Snodgrass
Evaluation Of Publicly Available Maize Germplasm Adaptation To Environments In Nebraska, Garrett Snodgrass
Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research
Publicly available maize germplasm represents an important resource for breeding programs seeking to expand genetic diversity and improve hybrid performance. However, effective use requires characterization of per se phenotypic performance of parental lines and evaluation of the parental line’s hybrid progeny adaptation to a given target population of environments. Furthermore, understanding population structure and heterotic grouping is imperative for maximizing efficiency of breeding decisions. The objectives of this study were to (1) evaluate phenotypic performance of parental lines and hybrids across environments in Nebraska, and to (2) refine heterotic group classification of parental lines within the University of Nebraska-Lincoln’s Hybrid …
Examining How Continuous Professional Development Shapes Teaching Practice And Student Learning Outcomes, Jane Rarieya, Mary Oluga, Nyagwegwe Wango
Examining How Continuous Professional Development Shapes Teaching Practice And Student Learning Outcomes, Jane Rarieya, Mary Oluga, Nyagwegwe Wango
Institute for Educational Development, East Africa
Purpose: This study examines how Teacher Continuous Professional Development (TCPD) initiatives implemented through the Strengthening Education Systems in East Africa (SESEA) and Foundation for Learning (F4L) projects influence teaching practices and foundational learning outcomes in Tanzania, Kenya, and Uganda.
Methodology: The study employed a mixed-methods research design using longitudinal data from classroom observations, teacher questionnaires, student assessments, and key informant interviews. Data were collected from trained teachers, teacher educators, school leaders, and learners across selected project regions to evaluate changes in instructional practices and learning outcomes.
Findings: The findings indicate that TCPD significantly improved teachers’ adoption of child-centered, play-based, inclusive, …
Data-Driven Non-Precipitation Echo Removal Of Nexrad Radars Based On A Random Forest Classifier Using Polarimetric Observations And Goes-16 Data, Munsung Keem, Bong Chul Seo, Witold F. Krajewski, Sangdan Kim
Data-Driven Non-Precipitation Echo Removal Of Nexrad Radars Based On A Random Forest Classifier Using Polarimetric Observations And Goes-16 Data, Munsung Keem, Bong Chul Seo, Witold F. Krajewski, Sangdan Kim
Civil, Architectural and Environmental Engineering Faculty Research & Creative Works
Highlights: What are the main findings? A Random Forest-based model using dual-polarimetric radar features achieves >99% accuracy in classifying precipitation and non-precipitation echoes. Multi-scale spatial variability features enhance discrimination between genuine precipitation and spurious echoes. Fusion of GOES-16 infrared satellite data with NEXRAD radar effectively removes non-precipitation echoes with precipitation-like signatures, including wind turbine clutter. A CAPPI scan strategy improves near-radar precipitation detection by recovering valid echoes misclassified at the lowest elevation due to side-lobe interference and limited sampling volume. What are the implications of the main findings? The model's robustness to noise and overfitting, combined with minimal hyperparameter tuning, …
Retained Placenta Removal Device (Womb-A), Savannah Fujimoto, Ciana Villar, Edward Barba
Retained Placenta Removal Device (Womb-A), Savannah Fujimoto, Ciana Villar, Edward Barba
Biomedical Engineering
Womb-a aims to design a safe, minimally invasive, and effective product that solves the issue of removing retained placentas after childbirth reducing the risk of infection and uterine trauma. Womb-a brings a handheld motorized device that can be used at the bedside immediately after delivery of a baby. Retained placentas happen to approximately 1-3% of deliveries [1] which elevates the likelihood of postpartum infection and hemorrhaging. Current solutions include manual removal, windmill technique, and D&C which individually have severe issues such as elevating risk of infection, inconsistent removal of adhered placenta, and surgical complications. The Womb-a aims to mitigate these …
Geographic Access To Pediatric Ecmo And Ecpr: A Geospatial Study Of Transport Networks And Disparities., Allan M. Joseph, Andrew J. Lautz, Carlie N. Myers, Ranjit S. Chima, Juan P. Gurria, Shafee Salloum, Wendy Hasson, Matthew P. Malone, Jenna Miller, Maya L. Dewan
Geographic Access To Pediatric Ecmo And Ecpr: A Geospatial Study Of Transport Networks And Disparities., Allan M. Joseph, Andrew J. Lautz, Carlie N. Myers, Ranjit S. Chima, Juan P. Gurria, Shafee Salloum, Wendy Hasson, Matthew P. Malone, Jenna Miller, Maya L. Dewan
Manuscripts, Articles, Book Chapters and Other Papers
BACKGROUND AND AIM: Extracorporeal membrane oxygenation (ECMO) can help children survive severe cardiac and/or respiratory failure, but it is only provided in specialized centers. There are disparities in access by ground transport to ECMO services, but it is unknown to what extent interfacility transfer systems can expand access. Additionally, the number of children who live in proximity to centers that perform extracorporeal cardiopulmonary resuscitation (ECPR) to be potential candidates in case of out-of-hospital cardiac arrest (OHCA) is unknown. We conducted a geospatial analysis to answer these questions.
METHODS: We conducted a geospatial analysis of the Extracorporeal Life Support Organization (ELSO) …
Molecular Landscape In Limb Anomalies: Diagnostic Yield And New Candidate Genes., Akram Mokhtari, Jade Charbonneau, Valancy Miranda, Khadijé Jizi, Marie-Ange Delrue, Patricia Egerszegi, Isabelle Thiffault, Philippe M. Campeau
Molecular Landscape In Limb Anomalies: Diagnostic Yield And New Candidate Genes., Akram Mokhtari, Jade Charbonneau, Valancy Miranda, Khadijé Jizi, Marie-Ange Delrue, Patricia Egerszegi, Isabelle Thiffault, Philippe M. Campeau
Manuscripts, Articles, Book Chapters and Other Papers
Congenital limb anomalies remain without an etiological diagnosis in up to 65% of patients. To help close this gap, we describe the genetic diagnostic outcomes of a large cohort. Patients whose primary indication for genetic consultation was a limb anomaly were included from 2014 to 2024. Demographic, investigation, and diagnostic information were extracted, described, and compared. One hundred and thirty-two patients were included in the final cohort, with an average molecular diagnostic yield of 36%. The most common conditions were polydactyly (24%) and radial anomalies (19%). Fifty percent had syndromic features. Seven (5%) patients underwent chromosomal microarray (CMA) only, 81 …
Use Of A Cystatin C-Based Gfr Equation In A Population Pharmacokinetic Model Of Methotrexate Clearance In Adult Patients With Lymphoma., Zachary L. Taylor, Erin F. Barreto, Kristin C. Cole, Andrew D. Rule, Kianoush B. Kashani, Nelson Leung, Carrie A. Thompson, Thomas E. Witzig, Laura Ramsey, Jason N. Barreto
Use Of A Cystatin C-Based Gfr Equation In A Population Pharmacokinetic Model Of Methotrexate Clearance In Adult Patients With Lymphoma., Zachary L. Taylor, Erin F. Barreto, Kristin C. Cole, Andrew D. Rule, Kianoush B. Kashani, Nelson Leung, Carrie A. Thompson, Thomas E. Witzig, Laura Ramsey, Jason N. Barreto
Manuscripts, Articles, Book Chapters and Other Papers
BACKGROUND: High-dose methotrexate (HDMTX) is a key treatment for lymphoma with central nervous system involvement. Whether incorporating cystatin C into glomerular filtration rate estimation improves methotrexate (MTX) clearance prediction remains unclear.
OBJECTIVES: We aimed to evaluate whether cystatin C-inclusive glomerular filtration rate equations improve MTX clearance prediction and to explore the relationship between MTX exposure and acute kidney injury (AKI) in adult patients with lymphoma receiving HDMTX.
METHODS: This was a prospective single-center study performed on 80 adult patients with lymphoma receiving HDMTX (1.5-8 g/m2) over a 4-h infusion. A population pharmacokinetic model was constructed using data from …
Impact Of Cyp2d6 Genotype And Inhibitor Use On Risperidone Metabolism In Children: Functional Insights Into The *17 And *29 Alleles., Matthew H. Bennett, Ethan A. Poweleit, Samuel E. Vaughn, Brandon Retke, Paul C. Toren, Jeffrey R. Strawn, Laura Ramsey
Impact Of Cyp2d6 Genotype And Inhibitor Use On Risperidone Metabolism In Children: Functional Insights Into The *17 And *29 Alleles., Matthew H. Bennett, Ethan A. Poweleit, Samuel E. Vaughn, Brandon Retke, Paul C. Toren, Jeffrey R. Strawn, Laura Ramsey
Manuscripts, Articles, Book Chapters and Other Papers
Risperidone, an atypical antipsychotic, is increasingly prescribed in pediatric patients with psychiatric disorders. It is primarily metabolized by CYP2D6 to 9-hydroxyrisperidone, an active metabolite associated with a higher risk of adverse effects. The CYP2D6*17 and *29 alleles are prevalent in individuals of African ancestry and less studied than variants found in European ancestry individuals. This knowledge gap contributes to differences in health outcomes in individuals of non-European origin. The primary objective of this study is to replicate recently identified risperidone-specific activity for the CYP2D6*17 and *29 alleles. During psychiatric hospitalization, CYP2D6 was genotyped as part of routine care. Remnant plasma …
Leappt: Leveraging Generative Artificial Intelligence-Pediatric Pulmonology Training. Curriculum And Content Development., Alvin Singh, Erin Khan, Mary Moffatt
Leappt: Leveraging Generative Artificial Intelligence-Pediatric Pulmonology Training. Curriculum And Content Development., Alvin Singh, Erin Khan, Mary Moffatt
Manuscripts, Articles, Book Chapters and Other Papers
After redesigning the curriculum of the pediatric pulmonology fellowship program at Children's Mercy-Kansas City, leadership continued to make changes based on feedback from a faculty survey concerned about the quality and structure of didactics. These changes included leveraging generative artificial intelligence to create a detailed course content outline containing specific objectives and study points for each subject related to pediatric pulmonology. Using the content outline as a foundational reference for learners, fellowship leadership continues to enhance the curriculum by creating testing questions, flipped classroom sessions and evaluations, and hope that these specific changes will help address decreased passing rates on …
Stroke Increases Motor Output Variability During Maximal Voluntary Isometric Contractions Of Knee Extensor Muscles In Adults, Zhilun Zhou, Stephanie Christine Wolfe, Brian Schmit, Matthew J. Durand, Sandra Hunter, Allison Hyngstrom
Stroke Increases Motor Output Variability During Maximal Voluntary Isometric Contractions Of Knee Extensor Muscles In Adults, Zhilun Zhou, Stephanie Christine Wolfe, Brian Schmit, Matthew J. Durand, Sandra Hunter, Allison Hyngstrom
Physical Therapy Faculty Research and Publications
Greater motor output variability (MOV, inconsistency and unsteadiness) during submaximal tasks post stroke is associated with poorer motor performance. However, little is known about MOV during maximal tasks and relationships with clinical measures of motor performance among stroke survivors. This study determined inconsistency (across discrete attempts) and unsteadiness (within a single attempt) during knee extension maximal voluntary isometric contractions (MVICs) in stroke survivors and neurotypical controls. Forty-three stroke survivors (28 female) and 31 age-matched neurotypical controls (15 female) performed a minimum of five knee extension MVICs with paretic and non-paretic legs (stroke) or dominant leg (controls). Inconsistency was calculated as …