Digital Commons Network^™

Heterocyclic‐Fused Squaramides: Anionophores With Antimicrobial Activity, Luke Edward Brennan, Chris Samuel Hawes, Kevin Kavanagh, Robert Brian Peter Elmes

Research Outputs: 2025-Present

Antimicrobial resistance is regarded as one of the foremost public health risks of the 21st century, highlighting the need for new antimicrobial agents and chemical tools to interrogate their biological activity. Artificial transmembrane anion transporters have emerged as promising supramolecular scaffolds in this context, having demonstrated membrane activity in mammalian systems and showing growing potential in antimicrobial research. Here, we report a series of heterocycle‐fused squaramide anionophores capable of binding and transporting chloride. Several members of this series display measurable antimicrobial activity, alongside evidence of intracellular chloride modulation in bacterial cells. Taken together, these findings indicate that membrane localisation and …

Sea Changes In Sue-And-Settle Policy: The Tides Of Transparency And Expediency, Evan B. Fitzgerald

Villanova Environmental Law Journal (1991 - )

No abstract provided.

Glavin Ivy V. Wellpath

2026 Decisions

USDC for the Western District of Pennsylvania

Keith Whitmore V. Superintendent Forest Sci

2026 Decisions

USDC for the Eastern District of Pennsylvania

Adapting Peer Review Of Electronic Search Strategies For Single-Concept Hedges: Introducing Press-H, Jenn Ann Monnin, Lynn Kysh

Faculty & Staff Scholarship

No abstract provided.

A Survey-Based Exploratory Study Of Factors Influencing Women's Intentions To Utilise Pre-Exposure Prophylaxis In The Eastern Cape Province, South Africa: Sociodemographic Characteristics, Hiv Risk Behaviours And Transactional Sex, Rosemary Kalenga, Gary Sharp, Anne M. Teitelman, Monde Makiwane, Larry D. Icard, John B. Jemmott

College of Nursing Faculty Papers & Presentations

BACKGROUND: South Africa has the third-highest adult prevalence rate globally, with women comprising 64% of cases. Despite the accessibility of pre-exposure prophylaxis (PrEP), its adoption among women, particularly young women, remains alarmingly low.

OBJECTIVES: The objective of this initial investigation is to explore factors influencing the intentions of South African women to use PrEP, focusing on sociodemographic factors, HIV sexual risk behaviours and involvement in transactional sex.

DESIGN: The research utilised an exploratory design employing surveys.

METHODS: Surveys were conducted in 2015 with 64 women aged 19-49 residing in the Eastern Cape Province of South Africa. The data were analysed …

A Joint Optimization-Based Novel Attack For Genomic Beacon Reconstruction, Kousar Saleem, Si̇nem Sav

Turkish Journal of Electrical Engineering and Computer Sciences

Genomic data sharing has become an essential component of biomedical research, enabling large-scale collaborations and accelerating discoveries in human genetics. To balance the need for accessibility with privacy concerns, several controlled-access mechanisms have been proposed, including genomic beacons. Genomic beacons answer simple presence/absence queries about specific genetic variants. However, prior work has demonstrated that beacons remain vulnerable to genome reconstruction attacks, where an adversary can recover large portions of participants’ genomes using summary statistics. Building on insights from prior reconstruction attacks, we introduce an approach that unifies SNP correlation and allele frequency alignment objectives within a single-stage joint optimization framework. …

Cannabis Stigma And Symptom Management Considerations In Cancer Survivors: A Mixed-Methods Exploration Of Patient Perspectives, Sera Levy, Salimah Meghani, Brooke Worster, Colleen Kilanowski, Danielle Smith, Amy A. Case, Rebecca L. Ashare

Department of Medical Oncology Faculty Papers

PURPOSE: This study aims to assess for indications of stigma and attitudes toward cannabis among cancer survivors (CS) who use or consider the use of cannabis.

METHODS: This study employed a convergent, parallel mixed methods design utilizing focus group and questionnaire data to assess the presence of stigma among a sample of CS (n = 23) who use (n = 10) and do not use (n = 13) cannabis to manage symptoms. CS were recruited from a multi-site observational study in the Northeast U.S. region that assesses cannabis use among oncology patients.

RESULTS: A total of 23 CS participated in …

Draft Final Phase I Pre-Design Investigation Evaluation Report Blacktail Creek Riparian Actions Butte Priority Soils Operable Unit Of The Silver Bow Creek/Butte Area Superfund Site Silver Bow County, Montana, Hydrogeologic, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Draft Intermediate (60%) Remedial Design Report Blacktail Creek Riparian Actions Butte Priority Soils Operable Unit Of The Silver Bow Creek/Butte Area Superfund Site Silver Bow County, Montana, Hydrogeologic, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Draft Final Remedial Design Work Plan Blacktail Creek Riparian Actions Butte Priority Soils Operable Unit Of The Silver Bow Creek/Butte Area Superfund Site Silver Bow County, Montana, Hydrogeologic, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Uncovering Hidden Prognostic Patterns In Colorectal Cancer Histology Using Unsupervised Learning: A Computational Pathology Study, Wen-Tong Zhou, Yong Liu, Gang Yu, Kuan-Song Wang, Chao Xu, Jonathan Greenbaum, Chong Wu, Lin-Dong Jiang, Christopher J Papasian, Hong-Mei Xiao, Hong-Wen Deng

Faculty, Staff and Student Publications

Colorectal cancer (CRC) remains a leading cause of cancer mortality globally, yet current histopathological diagnostics capture only limited features. This study aimed to discover subtle, prognostically significant histomorphological patterns in CRC tissues using unsupervised deep learning. We developed a framework integrating convolutional neural networks with deep clustering, trained on 23,341 image patches from 493 patients. We identified 30 distinct histomorphological clusters from CRC tissue images. Through univariate and multivariate survival analyses, three clusters (Cluster13, Cluster19, and Cluster24) were consistently associated with patient prognosis. These clusters were integrated with clinical factors (T stage, N stage, and differentiation degree) to construct a …

Symptomatic Manifestations Of Hip Dysplasia In Young Adults: How Do Patients Present Before Or After Surgery? Results From A Social Media Cohort, John M. Gaddis, Amanda J. Wheeler, Erika Shults, Charles South, Stephen T. Duncan, Joel Wells

School of Medicine Publications

This study aimed to analyse the symptomatic differences of hip dysplasia before or after separate surgical interventions, including pain location and characteristics, severity, patient-reported outcomes, and a body pain diagram. A REDCap-based survey was distributed through social media from October 2023 to May 2024 and targeted individuals with current or past hip pain. The survey gathered data on demographics, comprehensive hip-specific history, and various patient-reported outcome measures. Of 509 completed surveys, 287 respondents reported a diagnosis of hip dysplasia and were divided into cohorts based on treatment history: no surgery (n = 65), post-periacetabular osteotomy (PAO) (n = 162), post-THA …

Authors’ Response To Letter To The Editor From Aphale, P, Et Al., Resident Autonomy In Pathology: Bridging Gaps Between Training And Practice, Bronwyn H. Bryant, Balaram Puligandla, Hailey L. Gosnell, Kristen Johnson, Stephanie Barak, Mary P. Berg, Julie Karp, Amanda Lofgreen, Cindy B. Mccloskey, Barbara E. C. Knollmann-Ritschel, Kristie L. White, W. Stephen Black-Schaffer

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

No abstract provided.

Glycative Stress Disrupts The Mitochondrial-Lysosome Axis And Promotes Geroconversion In Aging Cardiomyocytes, Diana Bou-Teen, Simonas Valiuska, Elisabet Miro-Casas, Chiara Rubeo, Elena Bonzon-Kulichenko, Zuzana Nichtova, Celia Fernandez-Sanz, Javier Inserte, Antonio Rodriguez-Sinovas, Begoña Benito, Eduard Ródenas-Alesina, Jesús Vázquez, Ignacio Ferreira-González, Marisol Ruiz-Meana

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Aging is a major risk factor for heart failure, yet the molecular mechanisms linking cardiac aging to the inflammatory pathophysiology of heart failure remain elusive. Mitochondrial dysfunction and defective organelle quality control are emerging hallmarks of the aging heart, but their biochemical underpinnings are poorly defined. Using comprehensive glycomics, we found that cardiac mitochondria from physiologically aged mice (≥ 20 months) are the major intracellular reservoirs of advanced glycation end products (AGEs), derived primarily from the chemical attack of some α-oxoaldehydes on proteins. This was associated with mild mitochondrial dysfunction and structural remodeling. Lysosomes in aged hearts were enlarged, more …

Understanding Tradeoffs In Clinical Text Extraction: Prompting, Retrieval-Augmented Generation, And Supervised Learning On Electronic Health Records, Tanya Yadav, Aditya Tekale, Jeff Chong, Mohammad Masum

Faculty Research, Scholarly, and Creative Activity

Clinical discharge summaries contain rich patient information but remain difficult to convert into structured representations for downstream analysis. Recent advances in large language models (LLMs) have introduced new approaches for clinical text extraction, yet their relative strengths compared with supervised methods remain unclear. This study presents a controlled evaluation of three dominant strategies for structured clinical information extraction from electronic health records: prompting-based extraction using LLMs, retrieval-augmented generation for terminology canonicalization, and supervised fine-tuning of domain-specific transformer models. Using discharge summaries from the MIMIC-IV dataset, we compare zero-shot, few-shot, and verification-based prompting across closed-source and open-source LLMs, evaluate retrieval-augmented canonicalization …

Prevalence Of Contact Child Sexual Abuse Victimization In The Us: Perpetration Types And Cohort Differences, Luciana C. Assini-Meytin, Rebecca L. Fix, Yi Sun, David Finkelhor, Elizabeth J. Letourneau, Keith Kaufman, Ben Mathews

Psychology Faculty Publications and Presentations

We investigated the prevalence of contact child sexual abuse (CSA) victimization in the US by comparing perpetration types in two adult cohorts. Participants included a nationally representative sample of adults aged 18–22 (n = 3,174) and 32–36 (n = 3,237). We used weighted proportions to obtain prevalences, Rao-Scott χ2 tests to assess for differences between cohorts. Analyses were also stratified by gender. The overall prevalence was 21.7% and similar between the two cohorts; 9.7% reported abuse by adults and 16.9% by youth under age 18. Most said that offenses were perpetrated by people known to them. CSA perpetration by youth …

Agnostic Tomography Of Stabilizer Product States, Sabee Grewal, Vishnu Iyer, William Kretschmer, Daniel Liang

Computer Science Faculty Publications and Presentations

We define a quantum learning task called agnostic tomography, where given copies of an arbitrary state ρ and a class of quantum states C, the goal is to output a succinct description of a state that approximates ρ at least as well as any state in C (up to some small error ε). This task generalizes ordinary quantum tomography of states in C and is more challenging because the learning algorithm must be robust to perturbations of ρ. We give an efficient agnostic tomography algorithm for the class C of n-qubit stabilizer product states. Assuming ρ has fidelity at least …

Human First: How Journalists Employ Ethics Of Care And Empathy When Covering School Shootings, Grace M. Ficara

USF Tampa Graduate Theses and Dissertations

School shootings have become a regular part of the news media cycle in the 21st century. Now, more than ever, journalists are needing to find innovative, yet empathetic, ways to deal with such crises as they navigate their own professional boundaries. Using the Ethics of Care model, this research intends to showcase how journalists have, willingly or unwillingly, utilized an empathetic approach when covering school shootings and how they use these tools to comfort their sources and themselves. Through semi - structured interviews of 9 participants, this study seeks to connect the practice of journalism with the one thing journalists …

Is There No Such Thing As Bad Pr? A Case Study Analysis Of Influencer Pseudo-Events, Authentic Crises, And Crises As Opportunity, And Paracrisis, Sofia Aparicio-Gallagher

USF Tampa Graduate Theses and Dissertations

There's no such thing as bad PR, and any publicity is good publicity are phrases coined by 19th-century P.T. Barnum, a showman and businessman known for his circus hoaxes (Hiergesell, 2025). The idea implies that all media attention, whether negative or positive, is beneficial to the organization or individual. The purpose of this study is to evaluate three brands; Tarte, Poppi, and Shein during a brand event to determine whether it was a pseudo-event created to gain awareness, or a genuine, unplanned crisis. Another purpose of the study was to determine if the event was used as an opportunity for …

Spin Pumping And Interfacial Anisotropy In Ultrathin Cobalt Heterostructures, Ibrahim Almuhanna

USF Tampa Graduate Theses and Dissertations

Interfaces dominate the behavior of ultrathin ferromagnets, where interfacial spin-orbit coupling(SOC) can strongly influence both magnetic anisotropy and magnetization dynamics. This thesis compares how a heavy-metal interface (Pt) and a semiconducting two-dimensional transition-metal dichalcogenide (TMD) interface (MoSe2) modify the static and dynamic magnetic properties of ultrathin Co. To isolate interface-driven effects, the heterostructure architecture is kept fixed (sapphire substrate and Si3N4 cap) while only the seeding/interface layer beneath Co is varied. MoSe2 is studied in two thickness conditions (monolayer and bilayer) to test layer-dependent trends.

Layer thicknesses are determined by X-ray reflectivity. Static magnetic properties are measured by in-plane vibrating …

Examining The Effect Of Household Socioeconomic Status And Maternal Characteristics On Child Developmental Delay In The United States, Samuel Ilori

USF Tampa Graduate Theses and Dissertations

Child developmental delay remains a pressing public health issue with lifelong implications. This study examines the association between household socioeconomic status, maternal characteristics, and child developmental delay using data from the 2023 National Survey of Children's Health (N = 35,399 female respondents). Bivariate analyses using Chi-square tests and binary logistic regression with sequential modeling were conducted. Results revealed that economic hardship, employment status, maternal mental health, maternal physical health, marital status, and race were significantly associated with child developmental delay (p<0.001). Educational level and poverty level showed no significant associations. Among mothers reporting poor mental health, 90.0% had a child with a delay, compared to 6.6% among those with good mental health. Every mother reporting poor physical health had a child with a delay, while virtually none with good or better physical health did. In the fully adjusted regression model, maternal mental and physical health remained the most powerful predictors, while economic hardship and employment status became non-significant once health was introduced, suggesting mediation. Maternal mental and physical health are the factors most strongly correlated with child developmental delay. Economic hardship matters primarily because it undermines maternal well-being. The COVID-19 pandemic likely intensified these dynamics by disrupting healthcare access and increasing economic instability. Supporting maternal health must be recognized as a fundamental strategy for promoting child development. Universal screening for maternal depression and physical health problems, integrated into pediatric and obstetric care, can identify at-risk mothers early. Policies that reduce economic hardship alleviate the chronic stress that undermines maternal health. Children thrive when their mothers are healthy.

Pd-L1, Tumor Mutational Burden, And Microbiome Signatures As Predictors Of Durable Immunotherapy Response In Metastatic Lung Cancer: A Multi-Omic Cohort Study, Wei Zhang, Li Chen, Minghao Liu, Xiaoyan Huang

Muthanna Medical Journal

Background: Immune checkpoint inhibitors (ICIs) have significantly improved outcomes in metastatic non–small cell lung cancer (NSCLC), yet durable clinical benefit (DCB) is achieved in only a subset of patients. Established biomarkers such as PD-L1 expression and tumor mutational burden (TMB) incompletely predict response, while emerging evidence suggests that gut microbiome composition may further modulate immunotherapy efficacy. We conducted a prospective multi-center study in China to evaluate the independent and integrated predictive value of PD-L1, TMB, and microbiome signatures for durable immunotherapy response. Methods: In this prospective cohort study, 286 patients with metastatic NSCLC receiving PD-1/PD-L1 inhibitors were enrolled across three …

Toward More Reliable Uavs: Interpretable Machine Learning For Understanding Propeller Fault Separability, Saadi Turied Kurdi, Luttfi A. Al-Haddad, Latif Ibraheem

Terra Joule Journal

This study investigates the fundamental limits of UAV propeller fault discrimination using an interpretable XGBoost–SHAP framework applied to the high-resolution DronePropA dataset. Three fault types—edge-cut, structural crack, and surface erosion—were evaluated across three severity levels under constrained flight conditions to isolate the physical signatures of degradation. A curated subset of 1 kHz IMU and ESC telemetry from Drone 1 (trajectory t1, speed SP1) enabled analysis of fault separability independent of kinematic variability. Despite deploying a moderately complex XGBoost classifier (300 estimators, depth = 6) and a comprehensive multi-domain feature set, the model achieved a performance ceiling of 38.04% accuracy and …

Impact Of Glass Powder As A Sustainable Material On The Workability, Strength, And Durability Properties In High-Performance Basalt Fiber Reinforced Concrete: A Statistical Analysis, Ahmed Fathi Mohamed Salih

Journal of Sustainable Construction Materials and Technologies

The global construction sector is increasingly challenged to balance environmental sustainability with the growing demand for durable, high-performance materials. As cement production continues to be a major source of anthropogenic CO2 emissions, the incorporation of alternative, low-impact binders has become a key strategy for reducing the environmental footprint of concrete. In this context, glass powder (GP)—a finely ground industrial by-product rich in amorphous silica—has emerged as a promising partial replacement for Portland cement. Its pozzolanic reactivity contributes to improved hydration and matrix densification, while its use also supports circular economy principles by diverting waste glass from landfills. At the same …

Learners’ Use And Perceptions Of The First Language Across Writing Stages: A Mixed-Methods Study In A Saudi Efl Context, Abdulrahman Ali Alqahtani

UB Journal for Humanities

The role of the first language (L1) in second-language (L2) writing has been widely debated; however, empirical research examining learners’ perceptions of L1 use across different stages of the writing process remains limited in the Saudi EFL context. Addressing this gap, this mixed-methods study investigates how EFL undergraduate students at the University of Bisha use their first language (Arabic) during the English writing process (pre-writing, drafting, and post-writing) and how they perceive its impact on their writing development. Participants were 36 undergraduate EFL learners with advanced English proficiency who completed a Likert-scale questionnaire measuring the frequency and the purposes of …

The Effect Of Transcranial Near-Infrared Laser Therapy On Chronic Ischemic Stroke Patients: A Randomized, Single-Blind, Sham-Controlled Trial, Merna Hassan, Osama Al Balah, Ahmed Hegazy, El Sayed Satour

Journal of the Saudi Heart Association

Background: Transcranial photobiomodulation (TPBM) using near-infrared (NIR) light is a novel, non-invasive neuromodulation strategy with potential to enhance neurorecovery. While preclinical studies are promising, clinical evidence in chronic stroke remains limited and inconsistent.

Objective: To evaluate the efficacy and safety of 980 nm transcranial NIR laser therapy as an adjunct to standard rehabilitation in improving neurological function in patients with chronic ischemic stroke.

Methods: In this randomized, single-blind, sham-controlled trial, 40 chronic ischemic stroke patients (>6 months post-onset, NIHSS 7-22) were allocated to active treatment (n=20) or sham control (n=20). The active group received 980 nm laser therapy (6W, …

Developing And Delphi-Validating A Phase-Based Sustainable Bsc Framework For Contractors' Sustainable Productivity Management In Developing Countries, Truong Van Luu, Le Minh Long Nguyen

HBRC Journal

This study develops and validates, using the Delphi method, a conceptual decision-support framework for construction contractors' sustainable productivity management (CSPM) in developing-country settings. Guided by KAMET rules, semi-structured interviews were conducted with 15 experts to elicit, refine, and reach consensus on a set of productivity management attributes that construction contractors can realistically apply. The outcome is 29 feasible productivity management attributes, organized under the four Sustainable Balanced Scorecard (SBSC) perspectives and mapped onto five management phases (planning, organizing, staffing, leading/coordination, and controlling). Rather than predicting or demonstrating productivity gains, the framework provides a practical roadmap for diagnosing capability gaps, prioritizing …

Sharing The Gold With The Mountain: A Proposed Quasi-Property Doctrine For Health Data Compensation, Taylor Col

Journal of Technology Law & Policy

This Note provides a legal answer to the moral question of whether a person should be compensated for lucrative health data that was collected from them. The moral question is examined through the lens of various doctrines in property, privacy, intellectual property, and ethics, in light of landmark cases concerning biomaterials and genetic information. A new doctrine for health data compensation is proposed, based on quasi-property and borrowing elements from equity, intellectual property, and profit-sharing. The proposed doctrine is evaluated by applying it to a hypothetical commercialization of one person’s health data via a precision medicine product.

2023 Annual Report, Tennessee. Department Of Treasury.

Treasurer’s Report

No abstract provided.