Digital Commons Network^™

Breath-Based Detection Of Liver Cancer Biomarkers Using An Swcnt-Fet Nano-Biosensor: Quantumatk, Mohamed Mohieb Rashdan

Theses

Early detection of liver cancer remains limited by the slow pace and invasiveness of current testing methods. This study proposes a single-walled carbon nanotube field-effect transistor (SWCNT-FET) designed to detect hexanal—a volatile organic compound (VOC) elevated in liver cancer—directly from exhaled breath. The device is modeled in QuantumATK using a semi-empirical Extended Hückel Hamiltonian within the non-equilibrium Green's function (NEGF) framework, emphasizing realistic contact physics by employing metallic SWCNT electrodes instead of conventional metal films. Zigzag channels with (11,0) and (12,0) chiralities are examined to analyze how geometry and contact matching influence charge transport. Simulations include current–voltage (I–V) characteristics and …

Automated Classification Of Periodontal Bone Loss In Periapical Radiographs Using Convolutional Neural Networks, Ramadhan Hardani Putra, Eha Renwi Astuti, Alhidayati Asymal, Aga Satria Nurrachman, Afifah Salsabila, Nasywa Athaillah Safitri, Fatina Yasmin, Andrew Nalley

Journal of Dentomaxillofacial Science

Objective: Periodontal diseases, including periodontitis, affected approximately 951.3 million people worldwide in 2021. Early detection and accurate diagnosis are crucial for determining effective treatment plans. Radiographic examination, particularly periapical radiographs, is a valuable method for assessing periodontal bone loss (PBL). However, classification of PBL stages is often influenced by observer subjectivity due to the complexity of manual measurement. This study aimed to develop and evaluate convolutional neural network (CNN) models for automated PBL classification in periapical radiographs.

Material and Methods: A dataset of 600 periapical radiographs was used, consisting of 480 training images, 60 validation images, and 60 testing images. …

Caries Risk Assessment As The Strongest Predictor Of Oral Health–Related Quality Of Life: A Cross-Sectional Multivariate Study Of Adolescent Students, Fadil Abdillah Arifin, Mila Febriany, Husnah Husein, Eva Novawaty

Journal of Dentomaxillofacial Science

Objective: This study aimed to determine the factors associated with oral health–related quality of life (OHRQoL) among adolescent students, with a particular focus on identifying the strongest predictor using a multivariate analytical approach.

Material and Methods: A cross-sectional study with 249 adolescent students in Sekolah Menengah Pertama Negeri 54 Makassar, Indonesia, was conducted. Clinical examinations were performed to assess dental caries experience using the Decayed, Missing, and Filled Teeth index (DMF-T), oral hygiene status using the Oral Hygiene Index–Simplified (OHI-S), Body Mass Index (BMI), sex, and caries risk level using the Caries Risk Assessment (CRA) tool, categorized into low, medium, …

2025 Annual Report Of The Collections, Metadata, & Resource Sharing Division, Maria Savova, Joshua Keyes, Candace Lebel, Casey Ann Mitchell, Melissa Perez

Library Staff Publications and Research

No abstract provided.

Ursinus Magazine, Spring 2026, Gundolf Graml, Steve Thomas, Jennifer L. Post-Whisted, Brad Drexler, Alyssa Kratz

Ursinus Magazine, 1995–Present

Gundolf Graml, Ph.D., named 20th President • $1.99 million grant boosts STEM pipeline • $1.49 million grant fuels APEX innovation center • Esports comes to Ursinus • Experiential Learning Week • Ursinus / Rochester partner on 4+1 business pathway • Ursinus launches global learning program • Students win America250PA innovation challenge • Athletics: A generous gift and a milestone • Bear2Bear Impact Award for leadership and service • Lenape Symposium returns to Ursinus • Wall Street on Main Street • Tuition Promise for Montgomery County students • Wrestler wins two Puerto Rico national titles • Paying it forward: A Montgomery …

Identifying Factors Influencing Occupational Therapy Decision-Making Regarding Telehealth, In-Person, And Hybrid Care Within A Veterans Affairs Healthcare Setting In South Carolina, Christina R. Smith

Senior Theses

Telehealth has become an increasing part of healthcare service delivery, expanding client access to services across disciplines, including occupational therapy. Existing research suggests that telehealth occupational therapy can produce similar outcomes to in-person care in certain populations; however, variability in patient characteristics, technological readiness, intervention demands, and environmental contexts influences its suitability, and limited research examines how practitioners determine the appropriate service delivery model. The purpose of this qualitative study is to explore the factors that influence occupational therapy practitioners within a Veterans Affairs healthcare setting in South Carolina when determining the appropriateness of telehealth, in-person, or hybrid service delivery …

Emerald Bowfin Amia Ocellicauda Ecology In Three Minnesota Lakes: Abundance, Age Analysis, Diet Composition, And Stable Isotope Food Web, Griffin Blegen

Biology Graduate Theses

The Emerald Bowfin Amia ocellicauda is a predatory fish species native to Minnesota that has often been discriminated against. This research expands ecological knowledge of Bowfin in Minnesota and provides population data to guide future management. Bowfin were sampled in the spring of 2024 and 2025 and a multi-census mark–recapture model was used to estimate abundance in three lakes. Estimated populations were 196 individuals in Little Toad Lake (95% CI: 116, 242) or 4.4 fish/littoral ha (95% CI: 2.7,5.7), 657 in Lake Sarah (95% CI: 436, 1014) or 4.2 fish/littoral ha (95% CI: 3.0, 6.7), and 612 in Gun Lake …

Understanding Educators' Perspectives On Universal Design For Learning In Co-Taught Elementary And Middle School Classrooms, Biancha Dipaola

JWU Dissertations & Theses

Universal Design for Learning (UDL) is an educational framework that encourages educators to proactively identify and address any potential barriers to learning before a lesson or concept is taught. UDL’s inclusive framework offers strategies for enhancing student engagement, representation, and action and expression, yet research on educators’ perspectives on UDL and its implementation in co-taught classrooms is limited. The literature identifies the lack of educator knowledge on neuroscience (Lopes et al., 2022), inadequate professional development (Chu et al., 2020), and systemic challenges such as common planning time and administrative support (Zhang et al., 2024) as barriers to implementing UDL, but …

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.

Long Term Effects Of Gestational Stress On Postpartum Cardiovascular Health In Female Rats, Arshaam Kordamiri

Senior Theses

Approximately 15% of women experience postpartum cardiovascular complications, including hypertension, cardiomyopathy, and heart failure. These conditions can impair maternal functioning and maternal-infant bonding, while increasing long-term health risks. Despite their severity, the underlying causes remain unclear. Stress is a known risk factor for cardiovascular disease (CVD), and gestation represents a period of heightened vulnerability. As CVD is a leading cause of maternal mortality, identifying contributing factors is critical.

Atrial natriuretic peptide (ANP), B-type natriuretic peptide (BNP), and troponin I are cardiac biomarkers involved in fluid regulation, blood pressure, and myocardial injury. We hypothesized that gestational stress alters cardiovascular function, geometry, …

Main Concept Analysis As A Predictor Of Aphasia Severity: Semantic, Phonological, And Executive Influences On Main Concept Performance, Chathurvedi Ganguru

Senior Theses

Main Concept Analysis is a discourse-based measure that captures the essential information conveyed during narrative speech and may serve as a functional indicator of communication ability in aphasia. This study will examine whether Main Concept composite scores derived from the Cinderella narrative task are associated with aphasia severity and identify the linguistic and cognitive factors that influence Main Concept performance. Participants will be drawn from the baseline cohort of the POLAR study and will include approximately 100 individuals with chronic post-stroke aphasia. Baseline measures include Western Aphasia Battery Aphasia Quotient, Pyramids and Palm Trees Test, Philadelphia Repetition Test, and Wechsler …

The Digital Divide: Voter Perceptions In The Age Of Social Media, Molly E. Griffin

Senior Theses

This thesis examines how social media shapes voter perceptions of candidate ideology and economic issues, and how these perceptions influence electoral decision-making. As digital platforms increasingly serve as primary sources of political information, exposure to negative content and patterns such as doom-scrolling can affect voters’ understanding of political realities. The study explores how social media reinforces preexisting beliefs, amplifies stereotypes, and creates echo chambers that shape both perceptions and choices in elections. Using survey data on US senators collected during the 2016, 2018, 2020, and 2022 election cycles, the research investigates the mechanisms by which digital media influence voter behavior. …

Structural-Functional Analyses Of The Huntingtin/Hap40 Complex In Drosophila And Humans, Stephen M Farmer, Amanda Solbach, Shiyu Xu, Beatriz Rios, Xin Ye, Amy Gao, Daniela Covarrubias, Yue Yu, Lili Ye, Vicky Chuong, Erin Furr Stimming, Haiqing Zhao, Sheng Zhang

Faculty, Staff and Student Publications

Huntington's disease (HD) is a neurodegenerative disorder caused by an abnormal CAG expansion in the Huntingtin (HTT) gene. Given its simple genetic cause but complex pathogenic mechanisms, interest in targeting HTT for HD treatment is growing, necessitating a clear understanding of HTT regulation. HTT protein primarily exists in a core complex with HAP40, forming a highly ordered structure with two large globular domains connected by a bridge. We previously demonstrated that HAP40 is conserved in

A Topic Modeling Analysis Of Stigma Dimensions, Social, And Related Behavioral Circumstances In Clinical Notes Among Patients With Hiv, Ziyi Chen, Yiyang Liu, Mattia Prosperi, Krishna Vaddiparti, Robert L Cook, Jiang Bian, Yi Guo, Yonghui Wu

Faculty, Staff and Student Publications

Objective: To characterize stigma dimensions, social, and related behavioral circumstances in people living with HIV (PLWHs) seeking care, using natural language processing methods applied to a large collection of electronic health record (EHR) clinical notes from a large integrated health system in the southeast United States.

Methods: We identified a cohort of PLWHs from the University of Florida (UF) Health Integrated Data Repository and performed topic modeling analysis using Latent Dirichlet Allocation (LDA) to uncover stigma-related dimensions and related social and behavioral contexts. Domain experts created a seed list of HIV-related stigma keywords, then applied a snowball strategy to iteratively …

A Methotrexate Dashboard: Integrating Mtxpk.Org Into The Electronic Health Record To Facilitate Model-Informed Care For Pediatric Patients Receiving High-Dose Methotrexate., Zachary L. Taylor, Nieko Punt, Chris Jenkinson, Bill Vidonish, Jennifer Young, Maureen M. O'Brien, Laura Ramsey

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: The MTXPK.org webtool facilitates model-informed supportive care and glucarpidase use in patients receiving high-dose methotrexate, but its reliance on manual data entry limits workflow integration. We aimed to highlight how translational informatics can advance, automate, and enhance the usability of clinical decision support tools by embedding MTXPK.org within the electronic health record (EHR).

METHODS: A human factors study with 6 clinical providers guided iterative prototype development. MTXPK.org was rebuilt within the EHR using a 3-tier architecture with Fast Healthcare Interoperability Resources-based data retrieval, automated pharmacokinetic modeling, and interactive visualization.

RESULTS: Two rounds of prototyping with task-based evaluations and contextual …

Unraveling The Nexus: Tumor Mutational Burden, Pd-L1 Expression, And Oncogenic Alterations In Non-Small Cell Lung Cancer Cytology Specimens, Min Dai, Francis Anthony San Lucas, Hector Alvarez, Leomar Ballester, Hui Chen, Keyur P Patel, Asif Rashid, Shun Rao, Mark J Routbort, Gloria Sura, Keith Sweeney, Gokce Toruner, Peng Wei, Richard Yang, Hyvan Dang, Rajyalakshmi Luthra, Sinchita Roy-Chowdhuri

Faculty, Staff and Student Publications

Background: PD-L1 expression and tumor mutational burden (TMB) are biomarkers for immune checkpoint inhibitor (ICI) therapy in non-small cell lung cancer (NSCLC); however, patients harboring oncogenic alterations have limited benefit from ICIs. The impact of oncogenic alterations on TMB and PD-L1 tumor proportion score in lung cytology specimens is poorly understood. Herein, the association between oncogenic alterations, TMB, and PD-L1 in NSCLC cytology specimens is explored.

Methods: Next-generation sequencing results from 312 NSCLC cytology specimens were retrospectively reviewed that interrogate 610 genes and select immuno-oncology signatures. TMB and PD-L1 immunohistochemical expression across oncogenic alterations were analyzed to explore associations.

Results: …

Impacts Of Listening Practice On Work Performance While Wearing Hearing Protection., Patricia Mcclain, Matthew G. Wisniewski

Manuscripts, Articles, Book Chapters and Other Papers

Individuals who work in loud environments often choose not to wear hearing protection devices (HPDs) while on the job. A prevailing justification for this decision involves potential performance impairments that come with HPD use. While previous research has been successful in characterizing the overwhelming prevalence of this issue, the question of how to go about improving HPD use still remains. In this study, we investigated the possibility that performance while wearing an HPD could improve if people are given listening training with a simulated HPD. Participants listened to podcasts in which the audio was filtered to simulate wearing an HPD …

Exploring The U.S. Public Service Employees’ Experiences With Gamified Cybersecurity Awareness Training, Bisola Adepoju

Human Resource Development Theses and Dissertations

The purpose of this qualitative study was to explore the U.S. public service employees' experiences with gamified cybersecurity awareness training. The primary research question guiding this inquiry was: How do U.S. public service employees make sense of their lived experiences with gamified cybersecurity awareness training? Two secondary questions examined what aspects of the training employees perceive as meaningful or disengaging, and how they interpret their motivation, engagement, and cybersecurity awareness during training. I chose an interpretive qualitative research design grounded in a constructivist paradigm and purposefully selected 11 U.S. public service employees who had participated in gamified cybersecurity awareness training. …

Enhancing Undergraduate Learning In Physics: The Effects Of Ai-Assisted And Ai-Guided Instruction On Knowledge, Self-Efficacy, And Satisfaction, Stephen Woods

Doctoral Dissertations and Master's Theses

Generative artificial intelligence (AI) tools such as large language models are increasingly used for self-directed learning, yet there is limited experimental evidence on whether they improve learning outcomes and whether theory-informed guidance adds value beyond AI use alone. Prior literature suggests that effective learning depends not only on access to information, but also on how instruction supports attention, working memory, long-term memory, and cognitive load, while also fostering motivational processes such as self-efficacy. Individual differences such as Need for Cognition may also shape how learners engage with cognitively demanding instructional tools such as AI.

The present study examined how different …

Information Theory Analysis Of The Solar Wind Magnetic Structures For Space Weather Prediction, Katherine Holland

Doctoral Dissertations and Master's Theses

Forecasting space weather at Earth is highly complicated, because of the limited measurements of the dynamic processes in the Sun that span multiple temporal, spatial, and energy-scales. The solar wind is a highly structured, multi-scale, evolving plasma and consists of coronal mass ejections (CMEs), stream interaction regions (SIRs), expanding flux tubes (Borovsky, 2008), and interplanetary magnetic field (IMF) discontinuities and fluctuations. The aim of this research is to improve our understanding of the evolution and dissipation of different scale-size solar wind magnetic structures as they move from the Sun-Earth Lagrange point 1 (L1) to Earth's bow shock and, ultimately, to …

Effect Of Curing Duration On Bridge Deck Concrete Performance, Zhaniya Omarova

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

This study evaluates the influence of curing duration on the performance of bridge deck concrete and investigates the feasibility of reducing curing periods without compromising structural and durability properties. Two concrete mixtures, a standard Nebraska Department of Transportation (NDOT) bridge deck mix (47BD) and an optimized reduced-cement-content mix (O47BD-R100), were evaluated under multiple curing durations Fresh, early-age, mechanical, durability, and shrinkage properties were assessed to characterize the effect of curing on concrete behavior. Internal relative humidity and temperature were monitored using embedded sensors to investigate moisture diffusion and its role in shrinkage development for lab specimens and full-scale slabs.

Results …

Advancing The Understanding Of Palliative Care In Singapore: Knowledge, Attitudes, Receptiveness, And The Moderating Role Of Media Information-Seeking Preferences, Su Lin Yeo, Angel Lee, Raymond Han Lip Ng, May O. Lwin, Yumin Lin

Research Collection Lee Kong Chian School Of Business

Introduction: Despite the growing demand for palliative care, this specialized medical care remains severely underutilized, with almost 50% of countries worldwide lacking access. Given that misperceptions and stigma continue to hinder progress in healthcare policy, this study aims to examine the relationships between palliative care knowledge, attitudes, and receptiveness to better understand how public health communication can enhance awareness and understanding of the topic in Singapore. Applying the adapted knowledge-attitude-practice (KAP) model, it further extends theory by examining the moderating role of media information-seeking between knowledge and receptiveness.Methods: Mixed-mode surveys involving 1,226 participants (926 online and 300 in-person respondents), representing …

Factors Associated With Venous Complications In Lower Extremity Free Flap Reconstruction: A Multivariate Analysis, Bora Kahramangil, Ellen Wang, Imran Rizvi, Jessica R Nye, Kylie Swiekatowski, Alexandra Dunker, Kate Liao, Michael H Haydon, Jeffrey G Trost, Mohin A Bhadkamkar

Faculty, Staff and Student Publications

Background: Due to their dependent location, lower extremity (LE) free flaps (FFs) are at increased risk for venous complications. This study analyzes risk factors of venous complications in LE FFs.

Methods: A single-center retrospective review was conducted of adult patients undergoing LE FF reconstruction from 2016 to 2025. Variables included demographics, wound and operative characteristics, and the number of venous anastomoses. The primary outcome was venous complications, defined as a composite variable encompassing venous congestion, flap loss due to venous causes, and flap hematoma.

Results: The cohort consisted of 370 patients undergoing LE FF reconstructions. Single venous anastomosis was used …

Correction: Prospective Trial Of Cerebrospinal Fluid Filtration After Aneurysmal Subarachnoid Hemorrhage Via Lumbar Catheter Extension (Pillar-Xt), Spiros L Blackburn, Marc A Babi, Andrew W Grande, Omar A Choudhri, Erik F Hauck, Christopher P Kellner, Michael C Giordano, Shivanand P Lad, Aaron R Mccabe

Faculty, Staff and Student Publications

This corrects the article "Prospective Trial of Cerebrospinal Fluid Filtration After Aneurysmal Subarachnoid Hemorrhage via Lumbar Catheter Extension (PILLAR-XT)" in volume 43 on page 934.

Aisc/Asce 2026 Student Steel Bridge Competition, Gabriel Barrantes, Matthew Beltran, Vance Debrabander, Robert Miller, Wyatt Nipp

Civil, Environmental and Sustainable Engineering Senior Theses

This report documents the design, fabrication, and construction of a 1:10 scale steel truss bridge developed by Santa Clara University’s Steel Bridge Team for the 2026 ASCE/AISC Student Steel Bridge Competition. Marking SCU’s first participation in the competition since 2013, the project was completed over a six and a half (6.5) month period from October 2025 to April 2026, with financial support from McCarthy Building Companies, Inc. The bridge design is a modular truss structure spanning 23 feet six and one quarter inches (6.25) inches, constructed entirely of low carbon steel in compliance with SSBC rulebook requirements. Primary structural members …

Dissecting The Genetic Basis Of Relevant Fruit Quality Traits In Interspecific Grapevines (Vitis Spp.), Venkateswara Rao Kadium, Ramesh Pilli, Andrej Svyentek, Zhuoyu Wang, John Stenger, Rajasekharreddy Bhoomireddy, Collin Auwarter, Xuehui Li, Harlene Hatterman-Valenti

APC Fund Awardees

Understanding the genetic control of fruit composition traits in interspecific grapevines (Vitis spp.) is crucial when breeding new cultivars with desirable fruit chemistry. To address this, a genome-wide association study (GWAS) was conducted using 587 genotypes derived from three elite selections. This study spanned 3 years (2020–2022) and with phenotyping conducted at three different timepoints within each season for a total of nine phenotyping events focused on nine fruit traits. Several strong and stable quantitative trait locus (QTL) associations were identified on chromosomes 6, 16, and 17 across multiple phenotyping events for most sugar- and acid-related traits. Notably, putative sugar …

Validating Ai Through Evaluation, Keith Porcaro, Carmela D'Antuno, Wilson Jeter, Bridgett Kohno, Alexander Mcelya, Nicolas Osorio, Melinda Xiaong, Demi Yang

Duke Center on Law & Technology

Stewards of legal information sites are facing enormous funder and partner pressure to "do AI" — but validating the quality of AI implementations remains a critical challenge, especially for client-facing applications. In the spring of 2026, the Duke AI Audits practicum worked with Scale Justice to help articulate the true foundational costs of scoping and building a generative AI application on a statewide LawHelp site.

Audit Report For Self-Help Chatbot, Keith Porcaro, Carmela D'Antuono, Wilson Jeter, Bridgett Kohno, Alexander Mcelya, Nikolas Osoria, Melinda Xiaong, Demi Yang

Duke Center on Law & Technology

This audit report investigates a self-help chatbot designed for Nevada litigants with family law or probate cases. The audit was conducted in Spring 2026 as part of Duke’s AI Audits and Access to Justice practicum, in partnership with the Nevada Administrative Office of the Courts.

A Legal Transplant Failure In The Ai Age, Xuan-Thao Nguyen

Articles

Thailand positions itself as the new AI-driven innovation hub in the Southeast Asia region as Big Tech companies invest billions in building new data centers to power the AI transformations in all sectors in Thailand. An integral part of Thailand’s new ambition is the legal transplant of personal data protection law from Europe. The transplant, however, is of form, not substance, as this Article illustrates the failure through in-depth analysis of Thailand’s Personal Data Protection Act and provides evidence of rampant violations and noncompliance by the largest ecommerce conglomerate and SMEs. This Article offers suggestions for Thailand to realign its …

Nh Guide To 4-H Dog Shows, Extension

UNH Cooperative Extension

No abstract provided.