Digital Commons Network^™

Reproducibility Of Statistically Significant Phase Iii Oncology Trials: An In Silico Meta-Epidemiological Analysis, Alexander D Sherry, Pavlos Msaouel, Avital M Miller, Timothy A Lin, Joseph Abi Jaoude, Ramez Kouzy, Adina H Passy, Tomer Meirson, Nikolaos Ignatiadis, Zachary R Mccaw, Erik Van Zwet, Ethan B Ludmir

Faculty, Staff and Student Publications

Purpose: The conventional assumption that P values ≤ 0.05 imply reproducible effects has come under recent criticism. This concern is particularly relevant in oncology, as phase III oncology trials, which directly inform practice, are usually not repeated. Using advanced modeling techniques, we investigated the relationship between P values and reproducibility in oncology.

Methods: We obtained the signal-to-noise ratio distribution in phase III oncology using outcomes from 632 two-arm superiority trials enrolling 496,219 patients. With this distribution, we estimated successful replication probability as the probability that a replicate trial, having the same design, effect size, and standard error, would have a …

Murmurations Of Modular Forms And P-Power Coefficients, Debanjana Kundu, Katharina Müller

School of Mathematical & Statistical Sciences Faculty Publications

We extend the work of N. Zubrilina on murmuration of modular forms to the case when prime-indexed coefficients are replaced by squares of primes. Our key observation is that the shape of the murmuration density is the same.

Projections Of Lightning‐Ignited Wildfire Risk In The Western United States, Dmitri A. Kalashnikov, John T. Abatzoglou, Frances V. Davenport, Zachary M. Labe, Paul C. Loikith, Danielle Touma, Deepti Singh

Geography Faculty Publications and Presentations

Cloud‐to‐ground (CG) lightning is a major source of summer wildfire ignition in the western United States (WUS). However, future projections of lightning are uncertain since lightning is not directly simulated by most global climate models. To address this issue, we use convolutional neural network (CNN)‐based parameterizations of daily June‐September CG lightning. CNN parameterizations of daily CG lightning occurrence at each grid cell use fields of three thermodynamic variables—ratio of surface Moist Static Energy (MSE) to 500 hPa saturation MSE, 700–500 hPa lapse rate, and 500 hPa relative humidity. Applying these parameterizations to the Community Earth System Model version 2 Large …

Exploring The Moderating Effect Of Boundary Management Strategy In A Remote Work Environment, Brandon M. Vasquez

Master's Theses

Remote work has evolved significantly, especially during the COVID-19 pandemic, and continues to influence employee experiences in both positive and negative ways. Managing the separation between work and personal life is of importance. More specifically, using a boundary management strategy of segmentation may be more effective than an integration strategy because those who separate the two domains of work and family/personal life may be less prone to conflict in their lives. The present study aimed to examine the moderating effect of boundary management strategy on the relationship between remote work and job satisfaction, work-life balance, and well-being. Specifically, it was …

Multiplex Imaging Mass Cytometry Reveals Prognostic Immunosuppressive Subpopulations And Macrophage-Driven Metastasis In Osteosarcoma, Benjamin B Gyau, Junyan Wang, Weiguo Wu, Brooks Scull, Angela M Major, Weidong Jin, Justin M M Cates, John Hicks, Tsz-Kwong Man

Faculty, Staff and Students Publications

Osteosarcoma is a type of bone cancer that mostly affects kids and teens. The biggest danger is when the cancer spreads to the lungs, and current treatments do not work well for those cases. Immunotherapy, which helps the body’s immune system fight cancer, has worked for other cancers but is limited for osteosarcoma because we do not fully understand the environment around the tumor. Our research looked at various cells around the tumor to study why patients have worse outcomes. We found that certain cells, called M2 macrophages (M2) and myeloid-derived suppressor cells (MDSC), which weaken the immune system, are …

Phosphorylation Toggles The Sars-Cov-2 Nucleocapsid Protein Between Two Membrane-Associated Condensate States, Bruna Favetta, Huan Wang, Jasmine Cubuk, Arjun Singh, Mayur Barai, Cesar Ramirez, Haiyan Zheng, Adam J Gormley, N Sanjeeva Murthy, Gregory Dignon, Andrea Soranno, Zheng Shi, Benjamin S Schuster

2020-Current year OA Pubs

The Nucleocapsid protein (N) of SARS-CoV-2 plays a critical role in the viral lifecycle by regulating RNA replication and by packaging the viral genome. N and RNA phase separate to form condensates that may be important for these functions. Both functions occur at membrane surfaces, but how N toggles between these two membrane-associated functional states is unclear. Here, we reveal that phosphorylation switches how N condensates interact with membranes, in part by modulating condensate material properties. Our studies also show that phosphorylation alters N's interaction with viral membrane proteins. We gain mechanistic insight through structural analysis and molecular simulations, which …

37th Convocation Pakistan

Speeches from convocations, inaugurations, and major events

No abstract provided.

Orchestrating Brilliance In The Recording Studio: Mixing Music To Record Music, Adrian Carroll

Imaginings: creative practice and inquiry

This paper is a report on a heuristic inquiry into music recording practice and workflow to arrive at the essence of experience. Through professional reflection on a music recording, we investigated the recording process and student experience; this was used to identify, explore and expose tacit professional practice. The central theme that unfolded revealed benefits in mixing music during a recording session. Other themes of workflow efficiency, and emotional expression, also emerged from the data collection. The research culminated in a creative synthesis in the form of a research question: Can live studio recordings be a viable option for artists, …

Bodies That Sparkle And Spill: A Poetics Of The Burlesque Parent, Lola Montgomery

Imaginings: creative practice and inquiry

The embodied experiences of burlesque performers during motherhood are explored in an online discussion, through femme theory, Bakhtin's grotesque body, and Butler's gender performativity. The participants' bodies are explored as sites of contestation, able to perform diverse roles simultaneously. Through performance, Mulvey's masculine gaze is inverted into a poetics of feminine praxis.

Transforming Leadership Behaviors And Thriving Through The Storm In A High Reliability Organization, Rajveer Kaur, Jiji Andrews, Kambree Baxter

Creating Healthy Work Environments (CHWE)

The structural inequities have affected critical care nurses, health care worker’s health and well-being (Durrah et al, 2022; Wells, S., 2024). Prioritizing nurse wellbeing has been formed to improve psychologically safe work environments associated with positively decreasing barriers in patient outcomes within the workforce (Wells, S., 2024). Authentic leaders developed patient advocacy, trusting relationships with their employees to increase the access to proper nursing services to enhance the ability to thrive at work ( Alhalal et al, 2024a; Durrah et al, 2022). Authentic leadership tool was introduced to design interventions and policies specifically for nurse manager’s authentic leadership style to …

Leveraging Meaningful Recognition To Create And Sustain Healthy Work Environments, Cindy Lefton

Creating Healthy Work Environments (CHWE)

Meaningful recognition, a form of feedback describing how one makes a difference in the life of another, also serves to illustrate the elements of a healthy work environment in action. Focusing on meaningful recognition as a catalyst to shape and drive healthy work environments, attendees will be introduced to evidence-based budget neutral practices they can utilize to positively impact team members, workplace culture, and patient experience.

Combining Organizational Assessment And Evidence-Based Strategies To Address Incivility In Nursing, Guillaume Ngonmeudje

Creating Healthy Work Environments (CHWE)

The workplace environment in healthcare is complex and negatively influenced by an increasing pattern of incivility. Recent reports of the increasing prevalence of incivility and related disruptive behaviors within nursing academic and clinical settings are alarming. Incivility threatens the sense of belonging needed to support and nurture the development of nursing students in the profession, and significantly impacts the work performance of front-line healthcare workers, contributing to medical errors and poor patient outcomes (Patel et al., 2022). Nurses and nursing students must be well equipped to effectively address incivility in the workplace and promote the collaboration necessary to optimize patient …

A Warm Welcome: Creating A Welcoming Environment For Nursing Student Clinicals Using A 3t Approach, Jeanine E. Gangeness, Sarah Heim, Linnea Benike

Creating Healthy Work Environments (CHWE)

Background: Establishing a welcoming clinical learning environment for nursing students is important as it has been shown to positively impact student learning, sense of security and belonging, recruitment, and development of professional caring behaviors. The first clinical day is often riddled with anxiety for nursing students. Clinical units today have higher acuity patients, staff nurses with fewer years of experience, and rapid adoption of new technologies and processes when compared to the past. These factors necessitate a renewed approach to how nursing students are introduced to clinical care. The purpose of this quality improvement project was to explore the impact …

Overcoming Challenges: Creating A Healthy Work Environment, Linda Eanes, Liji Mathew, Betty Phillips, Dalia Paul, Moncy Mathews

Creating Healthy Work Environments (CHWE)

A healthy work environment improves patient outcomes and promotes resiliency by supporting the wellbeing of the nurses. The purpose of our study was to describe labor and delivery nurses’ experiences in caring for patients during the COVID-19 pandemic. We used a descriptive phenomenological design and purposeful sampling to recruit experienced labor and delivery nurses for flexible semi-structured face-to-face audiotaped interviews. Constant comparison was used to analyze data. Ten nurses employed in a labor and delivery unit in two acute care hospitals in southern Texas participated and were interviewed from June through August 2022.

Five distinct themes were identified: Psychological stress …

Reshaping Workplace Well-Being: The Journey To Human Connection, Heike Doody, P. Ann Blaney

Creating Healthy Work Environments (CHWE)

As healthcare continues to evolve in post-Covid environment, nurse leaders face increasing challenges with guiding teams, improving engagement, and promoting overall wellbeing. Increasing work engagement is an important indicator of workforce sustainability and wellbeing (Schaufeli, 2021). Leaders foster a culture of wellbeing, safety, and support for employees in healthcare organizations with a human connection. The purpose was to reengage direct care nurses to implement wellbeing standards and reestablish the human connection among staff by utilizing engaging leadership concepts.

Faced with lack of council engagement, leaders from the Healthy Work Environment Council (HWEC) shifted their leadership style from transitional to engaging …

An Introduction To History Of Medicine, Mary E. Horton, Adan Rios

History of Medicine Seminar

Monthly Monday Seminars at Noon for the Academic Year:

• Attendance at seven sessions required for credit
• Includes Special Speakers as part of the TMC History of Medicine Society sponsored by Houston Methodist Hospital
• Spring merge with Baylor Medical College medical student elective
• Additional activities available:
  • Scavenger Hunt at the TMC Library Archives
  • Houston Methodist Hospital Lectures (Sponsored by the TMC History of Medicine Society)
  • Rice University Lectures
  • Baylor Medical College seminars

From Intra To Interdisciplinary: Growing An Inclusive Nicu Wellness Team, Christina Rose San Filipo

Creating Healthy Work Environments (CHWE)

Neonatal intensive care unit (NICU) teams care for some of the hospital’s most fragile and sick patients. Larger NICUs frequently care for more acute patients, increasing the risk of burnout among team members.1,2 These NICUs often see a larger volume of patients, presenting challenges to teaming and collaborating effectively as team sizes increase to meet patient care demands.1,2 The AACN Healthy Work Environment (HWE) assessment tool was deployed to nurses in an upstate NY level IV NICU. The lowest-scoring areas were true collaboration, skilled communication, and meaningful recognition. Based on HWE data, the ACE-15 Teamwork and Collaboration survey was distributed …

Overcoming Toxic Positivity: Leadership Strategies For Promoting Healthy Nursing Work Environments, Hannah Grace Shipp, Katherine Christine Hall

Creating Healthy Work Environments (CHWE)

In the post-COVID-19 landscape, many nurses report feeling abandoned (5), undervalued (6), and inadequately supported (2,3). As such, it is incumbent for organizational leaders to take action to support nursing staff and implement strategies that foster healthy work environments and promote nurses’ well-being. A potentially overlooked contributing factor is toxic positivity. While this phenomenon appears to be present in nursing, it remains underexplored. The purpose of this presentation is: (a) to provide an overview of the concept of toxic positivity, (b) to explore its potential impacts on patient care outcomes, and (c) to discuss strategies nurse leaders can employ to …

Reigniting The Passion: Alluring Our Future Leaders, Catherine J. Mohammed

Creating Healthy Work Environments (CHWE)

Background/Significance: Although the influence of leadership style on empowerment and job satisfaction of the workforce has been documented, there are few researchers who examined the influence of the leader’s experience in developing not only their own leadership skills in the creation and sustainment of healthy work environments but to engage and “train up” the development of our future nurse leaders. The current nursing workforce is struggling with engagement and retention and the lack of interest in leadership in the emerging generations.

The empirical evidence supports of the creation of the healthy work environment whether it is a Magnet designated facility …

Impact Of Accounting Information Systems And Islamic Organizational Culture On Information Quality, Oelma Arfannur Azizi, Busra Busra, Marjulin Marjulin

Arab Economic and Business Journal

Amid growing demands for transparency and accuracy in financial management, an effective Accounting Information System plays a crucial role in ensuring that financial data is accurately. However, the implementation of such technology must be supported by a strong organizational culture,. The method employed in this research is a quantitative approach, utilizing inferential statistics to explain the impact of various research variables. The statistical tool used is Structural Equation Modeling -. The results of this study indicate that both the Accounting Information System and Islamic Organizational Culture have a positive and significant impact on the quality of accounting information

Multidisciplinary Workplace Wellness Committee To Improve Employee Engagement, Fatima Arastu, Helen Chen, Hillary Duncan, Rich Elles

Creating Healthy Work Environments (CHWE)

Background: A healthy work environment is an active process that involves employees and the leadership team to meet the complexities of the health care settings. Post Pandemic, there’s been intentional efforts to redesign the worker well-being to reduce workplace stress and increase staff engagement (Grant et al., 2020, Lovejoy et.al., 2021). A healthy work environment is foundational to safety culture, as it promotes effective communication, collaboration, shared decisions-making, authentic leadership, and meaningful recognition (Grant et al., 2020, Vaughan, 2023). Employers have increasingly invested in workplace wellness programs to enhance employee health at the organizational level (Song & Baicker, 2019). However, …

Supporting A Healthy Work Environment By Attending To Nurse Mattering, Katherine Hall, Beth Epstein

Creating Healthy Work Environments (CHWE)

Background: Mattering, the feeling that you make a difference and are significant to others,1 is endorsed by the U.S. Surgeon General as an essential part of a healthy work environment.2 Mattering is negatively associated with nursing burnout and turnover, and targeted interventions to enhance nurses’ perceptions of mattering may be useful for making systemic changes to the nursing work environment. 3,4 To-date there are no studies that explore how nurses perceive they matter at work.

Purpose: To explore aspects of the health care work environment that influence nurses’ perceptions of mattering and identify workplace changes that can be made to …

Nurse Advocacy: Elevating The Voice Of Nurses From The Bedside To The Capitol, Judy Ong Ho

Creating Healthy Work Environments (CHWE)

Background: Workplace violence and nursing shortages are challenges for nurses. Studies have listed insufficient staffing and workplace violence as contributory factors to nurses leaving their jobs. This presentation aims to demonstrate how a healthcare system empowers, enables, and engages their nurses to collaborate with their Government Affairs team to advocate for resources and solutions through legislative efforts. Nurses use their professional expertise, knowledge, and experience to effectively communicate the challenges to the legislators.

Method: To prepare the nurses, training sessions, supplemented by FAQs were provided. Our healthcare system sponsored 80+ nurses to attend the 2023 Nurses Day at the Capitol …

System For Generating Immersive Experiences Via An Ai Pipeline And Sensory Protocol, Gaurav Umeshkumar Gupta

Defensive Publications Series

Current virtual reality (VR) content creation is complex, and the resulting sensory feedback from haptic devices relies on proprietary, pre-programmed effects. This limits the availability of personalized, deeply immersive experiences and creates a fragmented hardware ecosystem. The disclosed technology describes a method for generating multi-sensory VR experiences from user prompts. It uses an artificial intelligence pipeline to generate a narrative, visual assets, and a corresponding synchronized sensory track. A key component is an open communication protocol that enables standardized communication between any VR content and various haptic hardware devices. This approach facilitates the on-demand creation of cohesive and immersive experiences, …

Impact Of Care And Retention Rounds On Turnover Rate, Josephine D. Bodino, Jason Gruia, Deanna Kearney

Creating Healthy Work Environments (CHWE)

Stay interviews, a cost-effective tool, enable employers to identify and address potential issues, increasing employee satisfaction and reducing turnover rates. The average cost of turnover for one Registered Nurse, as per various data sources, ranges from [$46,100 to $ 61,100]. By implementing Stay Interviews, an increase in hospital savings can underscore the financial benefits of this strategy in the competitive landscape of employee engagement and retention.

A shared governance structure, alongside our commitment to true collaboration, addressed the organizations turnover issue. Nurses from the Healthy Work Environment and Staffing Committee and a diverse interprofessional team comprising of nursing leadership, clinical …

Advocating For Nurse Engagement: Cultivating Leadership And Resource Availability, Kasey Duffie Chance, Jacquelyn Smith, Brandy Simpler

Creating Healthy Work Environments (CHWE)

Background: Approximately three million nurses report to work daily across the United States (Alexander et al., 2021). Despite this number, there is a critical nursing shortage that must be addressed (Bong, 2019). Nurses work in a high-demand profession that affects their ability to acquire or conserve resources to stay engaged and avoid burnout (Contreras et al., 2020; Paustian-Underdahl et al., 2023). Healthcare organizations must focus on retaining nurses by providing them with resources and tools to be engaged and provide quality care (Bong, 2019; Contreras et al., 2020; Othman & Nasurdin, 2019).

Methods: A review of literature was …

Faculty Newsletter Fall 2024, University Of Missouri-St. Louis Libraries

Library Publications

No abstract provided.

Proceedings Of The 2025 Berry Summer Thesis Institute, University Of Dayton. University Honors Program, Dorian Borbonus, Nicholas J. Canfield, Triet M. Cao, Thomas Crossman, Jeffrey Huettemann, Aung Myat Khaung, Chase Kinder, Elizabeth Krahe, Anh Duc Nguyen, Quynh Anh Nguyen, Anna M. Petre, Kayden G. Rothery, Anna M. Schmitz, Rachel Zeller

Proceedings of the Berry Summer Thesis Institute (2013-Present)

Thanks to a gift from the Berry Family Foundation and the Berry family, the University Honors Program launched the Berry Summer Thesis Institute in 2012. The institute introduces students in the University Honors Program to intensive research, scholarship opportunities and professional development. Each student pursues a 12-week summer thesis research project under the guidance of a UD faculty mentor. This contains the product of the students' research.

Faculty Senate Executive Committee Agenda August 25, 2025, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• 3:00 Call to Order
• Approval of Minutes - April 14, 2025
• 3:05 University Business
• 3:20 Faculty Senate Business
• 3:35 Information
• EPC Report - April 3, 2025
• Title IX
• 3:50 Reports
• Empowering Teaching Excellence
• Center for Instructional Design and Innovation
• 4:00 Old Business
• 4:05 New Business
• Adjourn: 4:30 pm

Gradual Activism In The Poem, "Mujer Negra", By Nancy Morejón, Leila Adelstein

Language Study as a Gateway to the Humanities

No abstract provided.