Digital Commons Network^™

Surface Marker Identification To Capture Live Circulating Tumor Cells In Metastatic Triple-Negative Breast Cancer, Bree M Lege, Khushali J Patel, Brendan Panici, Ping Gong, Michael T Lewis, Matthew J Ellis, Chonghui Cheng

Faculty, Staff and Students Publications

Metastatic triple-negative breast cancer (TNBC) is highly aggressive and lacks targeted therapies. Circulating tumor cells (CTC) are invaluable for monitoring metastatic tumor progression and treatment response but are difficult to capture because of their rarity and heterogeneity. Surface-based staining for live CTCs is essential to preserve RNA quality in single cells, but current markers tend to perform poorly on more mesenchymal tumor cells such as TNBCs. To enhance live TNBC CTC detection, we developed a workflow for live CTC capture and single-cell RNA sequencing (scRNA-seq). Using a mouse model of metastatic TNBC, we identified four new CTC surface markers, AHNAK2, …

Assigning Library E-Books As Textbooks: An Examination Of Collection Development Policies And User Education Practices At Minority-Serving Institutions, Michelle Ehrenpreis

Publications and Research

Assigning library e-books as course textbooks can help to alleviate the financial burden of college for many students. Accordingly, libraries include e-books in their collection development policies and strive to educate users on the availability of these texts via the use of library research guides. Previous studies discuss library collection strategies and intentions to use e-books as textbooks, but do not discuss continuous or permanent plans. This study examined library policies at Hispanic Service Institutions (HSI’s) and Historically Black Colleges and Universities (HBCU’s) to evaluate how these libraries approach and document their acquisitions of library e-books. Research guides at the …

Case Report: Primed Dendritic Cell Immunotherapy For Multiple Solid Tumors, Jeffrey Jones, Aly Alrabaa, William Decker, Luis Ferbeyre, Gregorio Viramontes, Rafael Gonzalez, Elideth Angulo, Antonio Zamudio, Raul Hernandez, Stephen Noga, Susana Hernandez-Reyes, Paul Zhang, Darryl Smith, Ara Karamanian, Luis Tamara, Dalton Greenwood, Matthew Halpert

Faculty, Staff and Students Publications

Many patients with advanced solid tumors ultimately develop resistance to conventional therapies, with especially limited options for those experiencing rapid progression or poor performance status, highlighting the need for personalized immunotherapies capable of inducing durable responses. In this retrospective case series, we describe the clinical course and outcomes of five adults (4 male, 1 female; median age 51 years [range, 39-62]) with metastatic solid tumors who achieved complete and durable remission following doubly loaded autologous dendritic cell therapy after failure of standard treatments, such as immune checkpoint inhibition, radiation, surgery, or endocrine therapy. Five patients, including prostate adenocarcinoma (n=1), malignant …

Evolving Burden Of Metabolic Dysfunction-Associated Steatotic Liver Disease And Its Complications In A Us Nationwide Healthcare System, Basim Ali, Ronald Samuel, Jennifer R Kramer, Liang Li, Xian Yu, Yumei Cao, Roxanne Desiderio, George Cholankeril, Steven M Asch, Hashem B El-Serag, Fasiha Kanwal

Faculty, Staff and Students Publications

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing public health problem. Measuring the burden of cirrhosis and its complications in people with MASLD is important to inform health care delivery.

Methods: We aimed to quantify the changes in the burden of MASLD-related cirrhosis and hepatocellular carcinoma (HCC) in a nationwide U.S. healthcare system. We used data from the Veterans Health Administration to examine temporal trends between 2010 and 2021 in the annual incidence and prevalence of cirrhosis and HCC in a large cohort of patients with MASLD, and to compare them to those in patients with hepatitis C …

Dismantling The Whiteness Of Legal Education, Doron Samuel-Siegel

Law Faculty Publications

Whiteness is not merely a racial description. Whiteness operates as allegiance to structural racism. The quiet engine of racial hierarchy, whiteness pervades and shapes traditional legal education, rendering legal pedagogy a structurally racist enterprise. Legal education not only reproduces the racism embedded in the law and legal profession, but also obscures the ways legal doctrine, professional norms, and pedagogical practices normalize, protect, and make invisible the advantages that accrue to whiteness itself. In doing so, itproduces lawyers ill-equipped to dismantle structural injustice.

This Article breaks new ground in the scholarship on legal pedagogy by defining whiteness as it operates within …

Alpacas: An Evaluation Methodology For No- Or Low-Cost Course Materials, Heather Leonard

Publications

Evaluating no- or low-cost course materials is a key concern for those supporting affordable learning initiatives. This article will review the current needs of researchers in no- or low-cost course material, the methods currently available to guide them, and a new method I have designed to specifically address needs that current methods cannot. This method, ALPACAS (Apt, License, Provenance, Accurate, Currency, Authority, and Sources), combines insights from several other well-known methods to assist librarians, course designers, and instructors in finding appropriate no- or low-cost course materials. For each item in ALPACAS, I will break down why it is important and …

Tuberculosis Presenting As Multiple Pulmonary Nodules Mimicking Malignancy, Abdel Martinez Borrego, Fatimah Bello, Brandon Cantazaro, Luisa Montoya, Frank Mediola

School of Medicine Publications

Multiple pulmonary nodules often raise concern for metastatic malignancy; however, the differential diagnosis is broad and includes infectious, inflammatory, granulomatous, vascular, and benign etiologies. Tuberculosis (TB), although uncommon, can present with multiple nodules that closely mimic metastatic disease on advanced imaging, requiring careful clinicoradiologic and microbiologic correlation. We describe a woman in her 50s who presented with dyspnea and new-onset heart failure, in whom imaging revealed mediastinal lymphadenopathy and bilateral pulmonary nodules concerning for malignancy. Evaluation was limited by concurrent COVID-19 infection, and CT-guided biopsy demonstrated necrotizing granulomas without evidence of malignancy or infection. She later re-presented with fever and …

Studies Towards Chemical Synthesis Of Homogeneous Prion Glycoprotein, Baotong Tian

Electronic Theses & Dissertations (2024 - present)

Prion diseases are fatal neurodegenerative disorders initiated by conformational misfolding of the prion protein (PrP), which generates pathogenic conformers that propagate via templated conversion and accumulate as aggregates. Glycosylation can modulate the PrP folding energy landscape, thereby biasing folding trajectories and the distribution of resulting conformational states. Bank vole PrP contains two N-linked glycosylation sites, and disentangling the contributions of site occupancy versus glycan structure requires homogeneous, site-defined glycoforms. In contrast, biosynthetic expression typically produces heterogeneous glycoform ensembles due to multistep Golgi processing, precluding independent control of glycan identity at each site. Here we report a chemical synthesis strategy of …

An Exploratory Mixed-Method Study Of Systems For Adhd Accommodation Implementation In New York State Middle Schools, Stacie Fenn Smith

Electronic Theses & Dissertations (2024 - present)

This mixed-method study examined organizational structures for ADHD accommodation implementation in New York State middle schools. While extensive research documents the effectiveness of specific ADHD accommodations, limited scholarly attention has focused on how educators organize themselves to deliver these supports consistently across multiple classroom settings. This study addressed that gap by investigating how educational leaders, teachers, and support staff structure systems for accommodation implementation. Grounded in Ecological Systems Theory (Bronfenbrenner, 1979) and Organizational Behavior Theory (Robbins & Judge, 2017), the study examined implementation across three organizational levels: building leaders, coordinators, and classroom teachers and support staff.

Data collection included a …

The Role Of The Coach In Student-Athlete Engagement, Christina Cobb

Electronic Theses & Dissertations (2024 - present)

Student engagement has long been recognized as a key indicator of student success in higher education, but limited research has examined engagement within the context of intercollegiate athletics. This qualitative case study explored how college coaches influence student-athlete engagement and how student-athletes utilize athletic department support services designed to promote engagement practices. Guided by Kuh et al.’s (2006) theory of student engagement, this study examined engagement through the lens of time and effort invested in educationally purposeful activities and the institutional environments that support or constrain participation.

Participants included six student-athletes, four coaches, and two athletic department administrators at a …

Rethinking Theories Of Political Discourse: The Limitations Of The Deliberative-Agonistic Split, Connor Moran

Electronic Theses & Dissertations (2024 - present)

What are “theories of political discourse,” why do they matter to political theory, and where do current ones fall short? This dissertation mines the existing resources availed by contemporary democratic theory in order to respond to the discursive challenge of “pernicious polarization,” particularly in the United States. The most comprehensive and influential theories of political discourse today have been furnished by the almost 40-year debate between deliberative democracy and agonism, both of which offer normative models centered on ameliorating the quality of political discourse.

The key finding of the dissertation is that the foundational works of the deliberative-agonistic split lack …

Constructing The Political “Other”: Affective Polarization And Cross-Ideological Portrayals On Instagram, Amanda M. Novellin

Electronic Theses & Dissertations (2024 - present)

Instagram has frequently been characterized by users as a platform that permits the circulation of hostile and adversarial political content due to comparatively limited moderation practices. In January 2025, Meta CEO Mark Zuckerberg announced changes to content moderation policies on Facebook and Instagram, including the removal of third-party fact-checking mechanisms. These platform-level changes further reshaped the political information environment in which online discourse occurs. However, even prior to these policy changes, Instagram had established itself as a prominent space for highly polarized political expression across the ideological spectrum.

This thesis examines how political polarization in the United States is reflected …

A Moderated Mediation Analysis Of Mental Health Literacy, Personal Stigma, And Gender On Help-Seeking Intentions In College Students, Anna M. Gentile

Electronic Theses & Dissertations (2024 - present)

Although many college students experience mental health challenges, help-seeking rates remain disproportionately low relative to reported need (Abelson et al., 2022). Identifying factors that facilitate help-seeking is critical for improving access to mental health support in this population. Prior research has identified mental health literacy as a significant predictor of help-seeking behavior and intentions among college students (Gorczynski et al., 2017; Smith & Shochet, 2011), whereas personal stigma, which is defined as a person’s negative attitude towards people with mental health concerns (Griffiths et al., 2006), has been consistently associated with reduced help-seeking (Abelson et al., 2022). Grounded in the …

Where Perspectives Meet: A Comparative Case Study Of How Participatory Practices Shape Deliberation During District-Level Educational Change, Gregory Vincent Massara

Electronic Theses & Dissertations (2024 - present)

Public education in the United States is socially and politically constructed, and ongoing reforms increasingly require collaborative engagement among diverse stakeholders amid heightened divisiveness. This mixed methods comparative case study examined how educational stakeholders make sense of one another’s perspectives during district-level collaborative work and the conditions that may foster conscientization, the critical reflection on one’s positionality. Two school districts developing a Profile of a Graduate (POG) and one engaged in deliberation about the relationship between public and charter schools within its community serve as comparative cases. The study triangulated meeting observations, a post-deliberation survey of stakeholders (N = 43), …

Misinformation And The Law, Gustavo Ribeiro

Scholarly Articles in Law Reviews & Journals

This Article bridges critical gaps between the growing body of social science research on misinformation and the persistent challenges jurors face in evaluating potentially unreliable evidence in courtrooms. Misinformation—a pervasive issue undermining decision-making in democratic societies—mirrors the difficulties jurors encounter in distinguishing truth from falsehood amid compelling but unreliable evidence. The consequences of such challenges are dire: wrongful convictions, racial disparities, and the erosion of public trust in the legal system.

This Article is the first piece of legal scholarship to provide a comprehensive discussion of current research on the psychological mechanisms underlying susceptibility to misinformation—such as the illusory truth …

Evaluation Of Tactile Cueing Embedded In An Aviation Headset On Pilot Altitude Control, Nicholas D. Wilson, Jessica Van Bree, Matthew Cleveland, Sunny Charakuru, Thomas Petros, Richard Ferraro, Kouhyar Tavakolian

Journal of Aviation/Aerospace Education & Research

This study evaluated the effectiveness of tactile cueing integrated into a pilot’s headset on pilot altitude control during simulated instrument conditions. Pilots typically rely on visual and auditory inputs to maintain situational awareness, but in high-workload or instrument meteorological conditions (IMC), these channels can become overloaded. One underutilized alternative for alerting is a tactile cueing apparatus. Using an X-Plane simulation of a Piper Archer equipped with a G-1000 avionics suite, 39 FAA-certified pilots flew two precision approaches. The experimental group (n = 20) received haptic cues via ear seal-embedded tactors when deviating from assigned altitude or glideslope. The control group …

A Review Of Current Research And Barriers To Access: Exploring Disparities In Pediatric Epilepsy Surgery, Nikita Das, Ali A Mohamed, Akshat Katyayan, Meena Vessell

Faculty, Staff and Students Publications

Background: Drug-resistant epilepsy (DRE) impacts at least 30% of pediatric epilepsy patients, adversely affecting neurodevelopment and quality of life, as well as risk of sudden unexplained death in epilepsy (SUDEP). While surgical intervention has proven to be an effective treatment for DRE, disparities in access to surgical care persist. Compared to adults, pediatric patients face unique challenges, including delayed recognition of surgical candidacy, limited access to specialized epilepsy centers, complex care coordination, and socioeconomic barriers.

Summary: This review explores the current state of pediatric epilepsy surgery, highlighting its effectiveness in achieving seizure freedom, improving neurocognitive outcomes, and reducing long-term healthcare …

Sodium Supplementation Algorithm To Promote Growth In Infants Who Are Preterm: Randomized Clinical Trial, Brianna M Liberio, Gregory M Sokol, Hannah Rakow, Kelly Mosesso, Valerie Hole, William W Wong, Shaji K Chacko, Jeffrey L Segar

Faculty, Staff and Students Publications

Objective: Evaluate the effectiveness of an algorithm using urine sodium (Na) concentration to guide dietary Na supplementation compared with standard care to promote growth in infants who are preterm.

Methods: A randomized trial was conducted in 4 neonatal units in Indianapolis, Indiana, involving infants between 250/7 to 296/7 weeks gestation with birthweight > 500 g. Study arms consisted of standard care or use of algorithm beginning at 14 to 17 days postnatal age. The primary outcomes were somatic growth (weight, length, and head circumference) measured by change in Z-score between aged 2 weeks and 36 weeks postmenstrual age (PMA). Secondary outcomes …

Workforce Development Academy For Youth, Hassan Hashemian

Mineta Transportation Institute

To address the need for a diverse workforce in the 21st century and create an awareness of the career paths and opportunities that exist in the transportation industry, the College of Engineering, Computer Science, and Technology at the California State University, Los Angeles (CSULA) has created the Workforce Development Academy for Youth (WDAY). The goal of this program is to build a pipeline of diverse, well-qualified young professionals for the transportation industry. The program works with high school students and teachers to offer academic courses, basic skills, workforce readiness training, internships, extracurricular activities, and career placements to prepare students and …

Developing And Evaluating A Young Adult Peer Mentor Training Program, Beth H Garland, Demonica L Jones, Cassandra J Enzler, Jean L Raphael, Albert C Hergenroeder, Rachel S Wolfe, Sarah C Graham, Constance M Wiemann

Faculty, Staff and Students Publications

Improving self-management skills for adolescents and emerging adults (AEA) with chronic health conditions is critical for successful transition to adult-based care. Peer-mentoring has been effective in improving the self-management skills of AEA. However, the components of training a successful young adult peer mentors (YAPM), especially interpersonal aspects of the role, such as communication skills and navigating mentee ambivalence are not well understood. This descriptive study created and pilot-tested a training curriculum for YAPM as part of a larger study to build self-management skills in the context of healthcare transition from pediatric to adult care. Five YAPM completed the training curriculum. …

The Lived Experience Of Pediatric Pain Management: Insights From Families And Providers, Samrithaa Balakrishnan, Annesha Dey, Aarti Bavare, Paul Checchia, Katherine Shwetz, Natasha Afonso

Faculty, Staff and Students Publications

Pain represents a subjective experience that manifests with emotional and physical discomfort. In pediatric care, pain management is especially complex due to communicative limitations, which creates a unique point of entry for parents to contribute to their child's treatment process. In this study, we explored whether families' perceptions of their child's pain and preferences for treatment were aligned with healthcare providers' pain management decisions. Using narrative-informed techniques in interviews with families and healthcare providers in pediatric care settings, we analyzed areas of concordance and discordance in pain assessment and treatment priorities. Our findings show that trust is built over time …

A Year In Review On Tuberculosis And Non-Tuberculous Mycobacteria Disease: A 2026 Update For Clinicians And Scientists, Simone Tunesi, Graham Bothamley, Gunar Günther, Yousra Kherabi, Liga Kuksa, Berit Lange, Christoph Lange, Natalie Lorent, Francesca Saluzzo, Martina Sester, Xenia Emilie Sinding Iversen, Marc Tebruegge, Conor Tweed, Anca Vasiliu, Lorenzo Guglielmetti, Tuberculosis Network European Trials Group (Tbnet)

Faculty, Staff and Students Publications

Background: Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide, while infections from non-tuberculous mycobacteria (NTM) represent a growing public health threat. In its 20th year of activity, the Tuberculosis Network European Trials group (TBnet; www.tbnet.eu) is one of the leading research networks in Europe. In this review, we summarize the main advances in TB and NTM that occurred in 2025.

Methods: We conducted a non-systematic review of articles published in 2025, with a strong emphasis on research with current or potential impact on clinical practice. We also selected the most impactful papers regarding the management of adult …

Employment Preferences Of Favela Residents, Mayara Felix, Beatriz Marcoje, Ieda Matavelli, Maria Clara Rodrigues

Cowles Foundation Discussion Papers

We document employment preferences of workers at the margin of informality using open-ended questions and discrete choice experiments in Brazil’s largest favela complex. Stated preferences emphasize pay and tangible job benefits rather than meaning or purpose, while primary complaints center on poor management, customers, and inflexible schedules. Workers exhibit high valuations for all formal sector amenities on average—unemployment insurance, parental leave, and termination notice—as well as for learning opportunities, but lower for non-formal sector amenities such as shorter commutes. Valuations vary systematically by employment sector in ways consistent with sorting: formal workers value formal amenities most, the self-employed value them …

Safe And Sound, Madeleine Allen

Music and Health Case Studies

No abstract provided.

1l Digital Usage Insights 2022-2026, Mendik Library

First Week 1L Digital Usage Insights

No abstract provided.

Pamphlet, The Great Book, Ellen Davies-Rodgers, 1973

Documents

A pamphlet advertising, "The Great Book, Calvary Protestant Episcopal Church, 1832-1972, Memphis, Tennessee" by Ellen Davies-Rodgers, published by The Plantation Press, Davies Plantation Road, Brunswick, Tennessee, 1973.

Reframing Trauma-Informed Care For Refugee And (Im)Migrant Health Systems: From Interpersonal Practice To Structurally Embedded Care, Hyojin Im, Sophia Banu, Aisha Koroma, Sarmaya Mustafayeva

Faculty, Staff and Students Publications

No abstract provided.

University Of New Hampshire Library Annual Report 2026: Better Together, Mairead Small Staid

Annual Reports and Statistics

No abstract provided.

A Firm’S Operational Risk: Data Set And Empirical Evidence, Vivek Astvansh, Joseph J. Simpson

International Business and Entrepreneurship Faculty Publications

Problem definition: A firm’s stakeholders would benefit from a quantitative measure of the managerial disclosure of its operational risk and the implications of this disclosure. However, a quantitative and scalable measure of a firm’s disclosed operational risk is unavailable. Thus, the firm’s stakeholders remain unaware of its disclosed operational risk and the risk’s implications. Methodology/results: U.S. law requires a public firm to textually disclose its operational and nonoperational risks in Item 1A of its annual report (i.e., Form 10-K). We train 64 transformer models on U.S. public firms’ Item 1A text to score 131,920 firm-years (16,959 firms, 2005 to 2024) …

Uncovering The Disciplinary Pulse Of Library And Information Science Through Large-Scale Topic Modelling Of Openalex Scholarly Literature, Sailendra Malik, Sukumar Mandal

Library Philosophy and Practice (e-journal)

Library and Information Science is among the oldest and intellectually pluralistic scholarly disciplines but the inner thematic structure has not been established. The article develops a systematic and data intensive mapping of the field by the Latent Dirichlet Allocation topic modelling to 7,824 articles in the English language indexed in OpenAlex in the year 2000 to 2025. A ten topic solution is an optimised solution that identifies a group of readable and sensible thematic domains including information literacy digital libraries scientometrics archives and scholarly communication. The analysis of temporal trajectory reveals that there have been consistent expansion at the emergent …