Digital Commons Network^™

Limosilactobacillus Reuteri Alleviates Proinflammatory T-Cell-Mediated Liver Injury And Transcriptomic Changes In Immunocompromised Mice, Ana Fadhel Alvarez, Zheng Yin, Beanna Okeugo, Alexander Banerjee, Meng Luo, Christopher M Taylor, Salomea Giorgberidze, Vaishali Harne, Rambabu Majji, Melissa N Munroe, Ji Ho Suh, Stephen T C Wong, Kang Ho Kim, Hari Krishna Yalamanchili, Suhair Al Salihi, Jon Marc Rhoads, Yuying Liu

Children’s Nutrition Research Center Staff Publications

Background: A deficiency of immunosuppressive regulatory T cells, as seen in scurfy (SF) mice or in IPEX syndrome in humans, can lead to multiorgan inflammation. Oral administration of the probiotic Limosilactobacillus reuteri Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM) 17938 prolongs survival and reduces Th1- and Th2-associated inflammation in SF mice. It remains unclear how DSM 17938-educated SF-CD4+ T cells modulate T-cell-liver communication.

Methods: To characterize CD4+ T cells from SF mice orally administered DSM 17938 (Prob-SF-CD4+ T cells) and to compare them with CD4+ T cells from SF mice (SF-CD4+ T cells), cells isolated from SF spleens were …

Disrupted Intrathalamic And Thalamocortical Structural Covariance Networks In Posttraumatic Stress Disorder, Nick Steele, Ahmed Hussain, Delin Sun, C Lexi Baird, Courtney Russell, Neda Jahanshad, Lauren E Salminen, Miranda Olff, Jessie L Frijling, Dick J Veltman, Saskia B J Koch, Laura Nawijn, Mirjam Van Zuiden, Li Wang, Ye Zhu, Gen Li, Dan J Stein, Jonathan Ipser, Sheri Koopowitz, Yuval Neria, Xi Zhu, Orren Ravid, Sigal Zilcha-Mano, Amit Lazarov, Benjamin Suarez-Jimenez, Ashley A Huggins, Jennifer Stevens, Kerry Ressler, Tanja Jovanovic, Sanne J H Van Rooij, Negar Fani, Emily L Dennis, David F Tate, David X Cifu, William C Walker, Elisabeth A Wilde, Ivan Rektor, Pavel Říha, Milissa L Kaufman, Lauren A M Lebois, Justin T Baker, Anthony King, Israel Liberzon, Mike Angstadt, Nicholas D Davenport, Seth G Disner, Scott R Sponheim, Thomas Straube, David Hofmann, Guang Ming Lu, Rongfeng Qi, Amit Etkin, Adi Maron-Katz, Xin Wang, Austin Kunch, Hong Xie, Yann Quidé, Wissam El-Hage, Shmuel Lissek, Hannah Berg, Steven E Bruce, Josh Cisler, Marisa Ross, Ryan Herringa, Daniel W Grupe, Jack B Nitschke, Richard J Davidson, Christine Larson, Terri A Deroon-Cassini, Carissa W Tomas, Jacklynn M Fitzgerald, Brandee Feola, Jennifer U Blackford, Bunmi O Olatunji, Geoffrey May, Steven M Nelson, Evan M Gordon, Chadi G Abdallah, Ruth Lanius, Maria Densmore, Jean Théberge, Richard W J Neufeld, Paul M Thompson, Rajendra A Morey

Faculty, Staff and Students Publications

The thalamus is a heterogeneous structure crucial for corticocortical communication, affective–perceptual integration, motor preparation, and memory-related functions. Posttraumatic stress disorder (PTSD) is characterized by various symptoms that likely relate to thalamic functions. Group-level and individual differential structural covariance (SC) analyses were conducted on intrathalamic, thalamocortical, and thalamosubcortical volumetric networks by segmenting structural MRI data from 2,784 subjects (PTSD n = 1,306; controls n = 1,478) into 25 thalamic nuclei per hemisphere. We found that PTSD was associated with stronger intrathalamic and thalamocortical network strength and stronger SC between the limbic thalamus and the somatomotor and auditory thalamus. PTSD severity was …

Professionalism In Practice: A Novel Approach To Integrating Small Doses Of Case-Based Professionalism Education Into Monthly Grand Rounds., Allison H Taylor, Andrew Caruso, Kelley Arredondo, Ellen M Friedman, Stacey R Rose

Faculty, Staff and Students Publications

Introduction: Professionalism is a critical construct across the health professions, though learners and faculty report feeling underprepared to navigate difficult situations; education in professionalism is challenged by the absence of a universal definition, time constraints due to overcrowded curricula, and the lack of consistent messaging to learners and faculty.

Methods: Professionalism in Practice (PiP) was developed to provide small doses (∼5 minutes) of case-based professionalism education as part of an existing educational forum (Grand Rounds) to optimize attendance of both learners and faculty. Each vignette highlighted a common professionalism challenge and was aligned with an AAMC professional competency. Sessions were …

Cultured Ex Vivo Human Brain Tissue Maintains Cell-Type Transcriptional Identities, J P Mcginnis, Sai Mallannagari, Maria Camila Guevara, Joshua Ortiz-Guzman, Benjamin D W Belfort, Suyang Bao, Snigdha Srivastava, Maria Morkas, Emily Ji, Kalman A Katlowitz, Angela Addison, Evelyne K Tantry, Carrie A Mohila, Melissa M Blessing, Nisha Gadgil, Samuel G Mcclugage, David F Bauer, William E Whitehead, Guillermo Aldave, Omar Tanweer, Naser Jaleel, Ali Jalali, Akash J Patel, Sameer A Sheth, Howard L Weiner, Shankar Gopinath, Ganesh Rao, Akdes Serin Harmanci, Daniel Curry, Benjamin R Arenkiel

Faculty, Staff and Students Publications

There is growing recognition of the need for human-based models of the nervous system and its diseases. Studies have investigated the electrophysiological properties of neurons in ex vivo human brain tissue, but the maintenance of other cell types remains unclear. We therefore used single-nucleus RNA sequencing of six patient samples to determine how well various cell types maintain their transcriptional identities over two weeks in organotypic slice culture (day 0, with 83 501 nuclei, and day 14, with 45 738). For each patient sample (two pediatric temporal lobectomies, one adult frontal cortex, two glioblastomas, and one medulloblastoma), we generated correlations …

Toward Ethical Provenance Tracking: The Ga4gh Model Data Access Agreement (Daa), Alexander Bernier, Bartha Maria Knoppers, Jonathan Lawson, Robyn Mcdougall, Maili Raven-Adams, Vasiliki Rahimzadeh

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Standardizing contractual clauses that govern data access enables research institutions to responsibly steward genomic and related health data while enabling its efficient downstream reuse.

Methods: We describe a document analysis study using both qualitative and comparative law analytical approaches to identify the most common categories of clauses from 29 different data access agreements used by human biomedical research consortia globally. We furthermore characterized the legal positions and standard practices for each common element of the agreement and synthesized across them to develop model clauses. A total of 3 discussion sessions were organized virtually to refine the clauses among members …

Imagining Genomics And Population Health In 2050: Anticipating Future Research, Policy, And Governance Needs, Bartha Maria Knoppers, Yann Joly, Ma Apos N H Zawati, Habiba Alsafar, Jeffrey C Barrett, Laura Blackburn, Brian Hon-Yin Chung, Martina C Cornel, Edward S Dove, David Glazer, Calvin Wai-Loon Ho, Muin J Khoury, Anna C F Lewis, Anneke Lucassen, Peter F R Mills, Colin Mitchell, Nicola Mulder, Ainsley J Newson, Anthony Ng, Paul D P Pharoah, Vasiliki Rahimzadeh, Megan C Roberts, Saskia C Sanderson, Jeffrey M Skopek, Ron Zimmern, Eric M Meslin

Center for Medical Ethics and Health Policy Staff Publications

No abstract provided.

Access To Digital Health Technologies: Personalized Framework And Global Perspectives, Sanjiv M Narayan, Mina K Chung, Demilade Adedinsewo, Luisa C C Brant, Leslie L Davis, David Duncker, Jennifer L Hall, Janet K Han, Carolyn S P Lam, Eldrin Lewis, Joseph Loscalzo, Manlio F Márquez, Vasiliki Rahimzadeh, Fatima Rodriguez, Prashanthan Sanders, Emma Svennberg, Kenneth Stein, Mintu Turakhia, Clyde Yancy, Antonis A Armoundas

Center for Medical Ethics and Health Policy Staff Publications

The emergence and rapid adoption of digital health technologies (DHT) present unprecedented opportunities to democratize and reduce disparities in health care by monitoring health and disease at the point of care in all patients. However, limited access to DHT is becoming a major obstacle to realizing these goals. Access to DHT is influenced not only by well-recognized social determinants of health, but also by digital determinants of health, such as digital literacy and the need for broad access to digital infrastructure, as well as commercial and economic factors. Addressing these challenges and designing unbiased systems of care are essential to …

From Passive To Powerful: Creating Engaging Resident-As-Teacher Modules, Anna E Rueda, Stephanie V Sherman, Sherita J Love, Glenn C Bridges, Wesley A Mayer, Mark J Harbott, Teri L Turner, Bani M Ratan

Faculty and Staff Publications

Background: We aimed to design, implement, and evaluate three novel institutional resident-as-teacher (RAT) e-modules for postgraduate year (PGY) 1, 2, and 3 and compare them to previously utilized online trainings.

Methods: We utilized PICRAT, a model examining both students' relationship with technology (passive, interactive, creative) and instructors' use of technology (replaces, amplifies, or transforms) to create interactive experiences that amplified teaching methodologies. We compared evaluations of the previous and new trainings with an unpaired t test. New modules were assessed with one-way analysis of variance for specialty-based acceptability and content analysis of two open-ended questions.

Results: Response rates averaged 93.2% …

Interdisciplinary Swiss Consensus Recommendations For Follow-Up After Radical Cystectomy And Trimodal Treatment For Muscle-Invasive Bladder Cancer, Ernest Kaufmann, Stefanie Aeppli, Andres Affentranger, Nicolas Arnold, Winfried Arnold, Fabian Aschwanden, Panagiotis Balermpas, Jörg Beyer, Uwe Bieri, Joost Boormanns, Richard Cathomas, Berardino De Bari, Marco Dressler, Daniel S Engeler, Andreas Erdmann, Andrea Gallina, Silvia Gomez, Matthias Guckenberger, Thomas Herrmann, Thomas Hermanns, Ilaria Lucca, Hubert John, Thomas Matthias Kessler, Jan Klein, Mohamed Laouiti, David Lauffer, Seth Paul Lerner, Agostino Mattei, Michael Müntener, Daniel Nguyen, Philipp Niederberger, Alexandros Papachristofilou, Lukas Prause, Paul Martin Putora, Karsten Reinhardt, Emanuela Salati, Philippe Sèbe, Mohamed Shelan, Silvan Sigg, Räto Thomas Strebel, Arnoud Jan Templeton, Ursula Vogl, Marian Severin Wettstein, Stephen Wyler, Deborah Zihler, Thomas Zilli, Daniel Zwahlen, Beat Roth, Christian Daniel Fankhauser

Faculty, Staff and Students Publications

Introduction: Radical cystectomy or trimodal therapy are treatment options for non-metastatic bladder cancer. However, there is limited evidence guiding post-treatment follow-up regimens, resulting in variations in care.

Objective: A Swiss consensus meeting aimed to identify gaps in follow-up strategies and subsequently tailoring follow-up protocols after curative treatment for bladder cancer.

Methods: A consensus meeting including participants from urology, oncology, radiation oncology, neuro-urology, international advisors, and patient representatives was held. 19 pre-formulated questions addressing follow-up duration, frequency, and modalities after radical cystectomy or trimodal therapy for bladder cancer were discussed and voted by participants.

Results: 42 experts from 22 institutions participated …

Personalizing Therapies Over The Course Of Hormone Receptor-Positive/Her2-Negative Metastatic Breast Cancer, Akshara Singareeka Raghavendra, Senthil Damodaran, Carlos H Barcenas, Suzanne A Fuqua, Rachel M Layman, Debu Tripathy

Faculty, Staff and Students Publications

The hormone receptor (HR)‐positive/human epidermal growth factor receptor 2 (HER2)‐negative breast cancer subtype accounts for most early and metastatic breast cancer (MBC) cases. HR‐positive/HER2‐negative MBC is characterized by a relatively prolonged, although variable, disease course and substantial intertumoral and intratumoral heterogeneity. Although endocrine‐based therapies remain the cornerstone of treatment, nearly all patients eventually develop resistance, which is increasingly addressed with biologically targeted agents and newer‐generation cytotoxic drugs. This review summarizes the current understanding of HR‐positive/HER2‐negative MBC biology, highlighting mechanisms of intrinsic and acquired resistance, including driver genomic alterations that, along with clinical factors, help guide therapeutic choices and sequencing. The …

Brainstem Encoding Of Speech In The Extended High Frequencies And Its Behavioral Correlates, Sajana Aryal, Fan-Yin Cheng, Srikanta K. Mishra, Spencer Smith

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Whether the auditory nervous system can extract and use speech information carried in the extended high-frequency (EHF; >8 kHz) range is an unresolved question in auditory neuroscience. Although EHF sensitivity is increasingly recognized as important for speech perception, it is unclear whether EHF hearing is directly or indirectly involved in real-world listening. This study examined brainstem neural encoding of EHF speech components and the relationship between EHF hearing sensitivity and both neural and perceptual speech processing. Envelope following responses (EFRs) to broadband and high-pass filtered (>4 kHz and >8 kHz) speech stimuli, along with digits-in-noise speech recognition thresholds under …

Aac In Schools: How District Infrastructure And At Specialists Shape Implementation Practices, Grace T. Clark, Lesley Rytel, Endever* Corbin, Madison Skibicki, Gabriella Pesantes

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose

Research on barriers to augmentative and alternative communication (AAC) implementation in schools has focused primarily on individual clinician factors rather than district infrastructure. This clinical focus article examined how the presence or absence of a dedicated assistive technology (AT) specialist was associated with differences in AAC implementation and the use of AAC as a Tier 1 support.

Method

Eighteen educators, including AT specialists, SLPs, and a special educator, from 17 U.S. school districts participated in a 75-minute structured Zoom focus group. They rated 11 statements about district AAC practices using a 4-point Likert scale and discussed their responses in …

Building Interprofessional Competency-Based Education Into Graduate Program Clinical Experiences: A Childhood Apraxia Of Speech And Sensory Processing Disorder Case Study Analysis, Kate Nealon, Zahava L. Friedman

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Supporting interprofessional competency-based education requires embedding educational opportunities within coursework and clinical experiences. This education prioritizes student engagement and learning from, with and about other professionals to support collaboration and communication amongst clinicians (CAIE, 2020). While the provision of interprofessional clinical opportunities is recommended, it is challenging to implement effectively in professional and pre-professional settings. Academic settings have the unique ability to provide interprofessional collaborative clinical experiences for students. This pilot study focuses on Speech Language Pathology (SLP) and Occupational Therapy (OT) clinical assessment experiences, specifically in the context of pediatric motor speech and sensory processing disorders. These disorders often …

In Search Of The Soul Of Creativity: Authorship, Agency, And Meaning In Refractive Collaboration With Generative Ai, Fatima Nazir

Theses and Dissertations

When images can be generated in seconds, what remains uniquely human in the act of creation? In Search of the Soul of Creativity: Authorship, Agency, and Meaning in Refractive Collaboration with Generative AI investigates where authorship, agency, and meaning reside within design practices mediated by generative AI. Rather than using AI to produce predictable results, this research deliberately relinquishes control to observe how generative systems interpret language through their own learned associations. Through a practice-led investigation across four generative models within the Higgsfield platform, user prompts were progressively shortened from full sentences to single words, revealing recurring patterns and cultural …

Markov Chain Wave Generative Adversarial Network For Bee Bioacoustic Signal Synthesis, Kumudu Samarappuli, Iman Ardekani, Mahsa Mohaghegh, Abdolhossein Sarrafzadeh

Electrical & Computer Engineering Faculty Publications

This paper presents a framework for synthesizing bee bioacoustic signals associated with hive events. While existing approaches like WaveGAN have shown promise in audio generation, they often fail to preserve the subtle temporal and spectral features of bioacoustic signals critical for event-specific classification. The proposed method, MCWaveGAN, extends WaveGAN with a Markov Chain refinement stage, producing synthetic signals that more closely match the distribution of real bioacoustic data. Experimental results show that this method captures signal characteristics more effectively than WaveGAN alone. Furthermore, when integrated into a classifier, synthesized signals improved hive status prediction accuracy. These results highlight the potential …

Digital Twin Technologies For Battery Systems: Advancements, Applications, And Future Directions, Seyed Saeed Madani, Yasmin Shabeer, Michael Fowler, Satyam Panchal, Carlos Ziebert, Hicham Chaoui, François Allard

Electrical & Computer Engineering Faculty Publications

The relationships among deep learning, edge computing, artificial intelligence (AI), and the most recent advancements in digital twin (DT) technology for battery energy storage systems are discussed in this paper. The study highlights the need for improved cloud-edge coordination, AI model development, and stronger cybersecurity features by demonstrating real-world applications of digital twin technology in electric vehicles (EVs), aircraft, and grid storage. It also described DT-based structures for fault detection, real-time monitoring, and optimization through standardization and battery management system (BMS) fusion. Because DT-based solutions for distributed energy resources (DERs) offer improved energy management systems, various studies have been conducted …

Dynamic Direct Voltage Control Under Maximum Torque Per Ampere For Interior Pmsms, Mohamad Alzayed, Hicham Chaoui, Alaref Elhaj

Electrical & Computer Engineering Faculty Publications

A novel method for controlling the speed of interior permanent magnet synchronous motors (IPMSMs), known as the current-sensing-based dynamic direct voltage control method under the maximum torque per ampere (MTPA) concept, is introduced. This technique achieves precise tracking of machine velocity by determining the optimal combination of voltage amplitude and angle for each specific motor velocity and current/load condition. Unlike previous studies, this approach takes into account the transient model of the machine, resulting in improved accuracy during dynamic operating conditions compared with existing methods in the literature. Moreover, a comparative analysis is conducted involving different direct voltage MTPA speed …

Generative Ai-Driven Optimization In Flexible And Reconfigurable Manufacturing Systems, Salah Hammedi, Hicham Chaoui, Lotfi Nabli

Electrical & Computer Engineering Faculty Publications

Flexible and Reconfigurable Manufacturing Systems (FRMSs) are essential for coping with variability in modern production environments; however, efficient scheduling and rapid reconfiguration remain challenging. This paper presents a hybrid optimization framework that integrates Colored Petri Net (CPN) modeling with Generative Artificial Intelligence (GenAI) to enhance scheduling performance and system adaptability. The CPN formalism ensures verifiable modeling of system dynamics, while a transformer-based generative model produces candidate scheduling and reconfiguration strategies. Simulation experiments were conducted under static, dynamic, and adaptive scenarios, including machine breakdowns and dynamic job arrivals. Performance was evaluated using makespan, mean flow time, machine utilization, and reconfiguration latency. …

Application Of A Hyaluronic Acid-Based Lotions Containing Hydroxyapatite Nano-Particles Approach For Treatment Of Initial Dental Caries, Zahra Gharavi, Zahra Namazi, Fatemehsadat Pishbin, Helia Givian, Maryam Torshabi, Farhood Najafi, Parisa Amdjadi

Electrical & Computer Engineering Faculty Publications

This study evaluated the remineralization potential of a ceramic–polyelectrolyte system, based on a novel combination of hydroxyapatite nanoparticles (HAp NPs) and a hyaluronic acid (HY) matrix, for dental enamel, a tissue that remains challenging to repair in clinical dentistry. Nano-Hydroxyapatite (nanoHAp) powder was synthesized and characterized using X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), field-emission scanning electron microscopy (FE-SEM), dynamic light scattering (DLS), and zeta potential analysis to confirm their crystalline structure, functional groups, morphology, particle size distribution, and colloidal stability. HY-based suspensions (remineralizing lotions) containing 5, 10, and 12 wt% of the synthesized nanoHAp particles were formulated via a …

Affordable Course Content And Open Education Resources For Undergraduate Courses Teaching Fundamentals Of Wireless Communications And Networking, Dimitrie C. Popescu, Otilia Popescu

Electrical & Computer Engineering Faculty Publications

Wireless communication systems and networks along with the services they provide have become an essential component of the modern 21st century society, fueling job growth in the wireless industry and increasing the need for engineers specialized in wireless communication systems. As a consequence, over the past two decades, undergraduate courses teaching fundamentals of wireless communication systems and networks have become common in electrical and computer engineering and technology programs. At the same time, the number of textbooks dedicated to wireless systems and networks published by mainstream publishers has also grown, with availability in various formats and offerings and a significant …

Automated Writer And Acquisition-Condition Classification Of Digitally Captured Handwriting Using Statistical Dynamic Features And Support Vector Machines, Long-Huang Tsai, Hsiang-Ju Lai, Wen-Chao Yang, Jiajun Jiang, Chung-Hao Chen

Electrical & Computer Engineering Faculty Publications

Digitally captured handwriting preserves pen trajectories and dynamic signals, but it also records hardware- and input-dependent properties that can confound forensic interpretation. This study revises a support vector machine (SVM) screening framework using 16,500 samples from 30 writers, 11 writing-content categories, and five acquisition conditions spanning three tablets and stylus or finger input. Twenty-four raw and derived time-series variables were summarized by maximum, minimum, mean, median, and standard deviation, yielding 120 features; the mode statistic was removed. Writing direction and angular velocity were recalculated with atan2-based vector formulas. Unavailable device/API channels were encoded as zero, and Z-score parameters were estimated …

Calvin Theological Seminary Academic Catalog 2026-2027, Calvin Theological Seminary

Seminary Academic Catalogs

No abstract provided.

Senolytic-Resistant Senescent Cells Have A Distinct Sasp Profile And Functional Impact: The Path To Developing Senosensitizers, Utkarsh Tripathi, Masayoshi Suda, Vagisha Kulshreshtha, Bryan T Piatkowski, Allyson K Palmer, Nino Giorgadze, Christina Inman, Nathan Gasek, Ming Xu, Kurt O Johnson, Tamar Pirtskhalava, Selim Chaib, Larissa P G Langhi Prata, Yi Zhu, Renuka Kandhaya-Pillai, Stefan G Tullius, Saranya P Wyles, Rambabu Majji, Hari Krishna Yalamanchili, David B Allison, Tamar Tchkonia, James L Kirkland

Faculty, Staff and Students Publications

The senescent cell (SC) fate is linked to aging, multiple disorders and diseases, and physical dysfunction. Senolytics, agents that selectively eliminate 30%-70% of SCs, act by transiently disabling the senescent cell antiapoptotic pathways (SCAPs), which defend those SCs that are proapoptotic and pro-inflammatory from their own senescence-associated secretory phenotype (SASP). Consistent with this, a JAK/STAT inhibitor, Ruxolitinib, which attenuates the pro-inflammatory SASP of senescent human preadipocytes, caused them to become "senolytic-resistant". Administering senolytics to obese mice selectively decreased the abundance of the subset of SCs that is pro-inflammatory. In cell cultures, the 30%-70% of human senescent preadipocytes or human umbilical …

Empowering Students To Engage With Climate Change Action: A Project-Based Module For Artificial Intelligence Literacy And Sustainability Thinking, Gabriel Granco, Yu Chen, Heather Macias, Yunfei Hou, Frank A. Gomez

Faculty Research, Scholarly, and Creative Activity

There is a growing need to prepare students to address complex environmental challenges, particularly climate change and the expanding role of artificial intelligence (AI). This article examines the adaptation of the Artificial Intelligence for Social Good (AI4SG) Ideation module, a pitch- and project-based teaching framework designed to integrate AI literacy and sustainability education. Implemented in an upper division climate change course, the module combines project-based learning, culturally responsive pedagogy, and geographic thinking to guide students in developing community-oriented AI proposals aligned with the United Nations Sustainable Development Goals (SDGs). Students were encouraged to approach their communities not through deficit lenses, …

Federal Protections For Farmworker Health In The United States: A Scoping Review Of Three Decades Of Research, Kaitlyn Alvarez Noli, Stephane Labossiere, Becca Berkey, Joseph G. Grzywacz

Faculty Research, Scholarly, and Creative Activity

Objectives: This scoping review characterizes the scope, methods, and framing of empirical research evaluating the Field Sanitation Standard (FSS) and Worker Protection Standard (WPS) of the U.S. Environmental Protection Agency and the U.S. Department of Labor respectively. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we identified empirical studies (1990–2024) assessing elements of either the FSS or WPS. Two reviewers screened and extracted study characteristics, designs, populations, and regulatory elements. Framing analysis of 1226 segments, identified using a large language model, from the studies' abstracts and introductions examined how authors conceptualized farmworkers' need for protection. …

Generation Of Impact Factor-Driven Security Rating Questionnaire Using Llms For Aiot Applications, Yuna Han, Simon Shim, Deva Kumar Gajulamandyam, Yeji Choi, Hyunwoo Lee, Hangbae Chang

Faculty Research, Scholarly, and Creative Activity

Industry 4.0 has transformed industries by accelerating the adoption of artificial intelligence of things (AIoT); however, it has also led to security risks, such as data leakage. Existing data protection research focuses on network layers, whereas application-layer rating systems rely on subjective evaluations, limiting consistency and applicability. This study proposes a scalable and objective AIoT security rating framework that clarifies ambiguities in the five-question rating system of the Korean Intellectual Property Office and unifies fragmented managerial and technical rating systems. By leveraging large language models (LLMs), the framework integrates a security rating model based on 14 impact factors with automated …

Seeds Of Sovereignty: Critical Public Health, Radical Sisterhood, And The Fight For Agricultural Justice, Andrew L. Carter

Faculty Research, Scholarly, and Creative Activity

This book explores the historical and contemporary influence of African, Caribbean, and Black (ACB) women farmers in the fight for food justice. ACB foodways have been dismantled over time due to centuries of settler colonialism, discriminatory agricultural policies, land and knowledge theft, cultural erasure, and direct forms of violence and intimidation—creating vast inequities in today’s food system. At the same time, mainstream public health responses to food insecurity and access in ACB communities often focus on short-term solutions that do not empower local communities and keep the status quo intact. These approaches overlook the broader structural constraints that maintain and …

Effect Of Graphene Oxide On The Upconversion Photoluminescence Behavior Of Er/Yb Co-Doped Pvdf-Go Composite Nanofibers, Saptasree Bose, Jack Ryan Summers, Bhupendra B. Srivastava, Karen Lozano, Victoria Padilla-Gainza

Mechanical Engineering Faculty Publications

Upconversion photoluminescence (UCPL) materials, particularly rare-earth (RE) doped nanoparticles, have garnered significant attention due to their ability to convert near-infrared (NIR) excitation into visible emission, offering benefits such as high photostability, long lifetimes, low autofluorescence, and deep tissue penetration. Among various platforms, polymer-based one-dimensional (1D) nanofibers with in-situ lanthanide doping remain relatively unexplored, despite their superior mechanical flexibility, processability, and potential for improved luminescence performance. In this study, we report the fabrication and UCPL quenching behavior of Er3+/Yb3+ co-doped polyvinylidene difluoride (PVDF) nanofibers incorporated with graphene oxide (GO), synthesized for the first time using the scalable Forcespinning® technique. PVDF, a …

The Energy Change Of Graphs Under Some Edges Deletions, Huan Lei Shi, Wen Huan Wang, Wasin So

Faculty Research, Scholarly, and Creative Activity

The energy ε(G) of a graph G is the sum of the absolute values of all the eigenvalues of its adjacency matrix. Gutman (2001) pointed out a problem to characterize the graph G and the edge e of G such that ε(G − e) ⩽ ε(G). Tang et al. (2023) gave a sufficient condition for ε(G − e) ⩽ ε(G), where e is not necessarily a cut-edge set or a cut edge. We deduce here a stronger conclusion than the results obtained by Tang et al. (2023). Our findings cover some known conclusions, such as the results obtained by Gutman …

Survodutide For Treatment Of Obesity: Baseline Characteristics Of Participants In A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial (Synchronize™-1), Carel W Le Roux, Sean Wharton, Biykem Bozkurt, Elke Platz, Gabriele Bleckert, Samina Ajaz Hussain, Martina Brueckmann, Elena Startseva, Isabel M Kloer, Lee M Kaplan

Faculty, Staff and Students Publications

Aims: Survodutide, a novel glucagon receptor and glucagon-like peptide-1 (GLP-1) receptor dual agonist, elicited significant weight loss in a phase 2 trial in individuals with obesity without type 2 diabetes (T2D). Two multinational phase 3 trials are investigating survodutide for obesity management in individuals with or without T2D. We report the baseline characteristics of participants in the SYNCHRONIZE-1 trial in adults with obesity without T2D (ClinicalTrials.gov: NCT06066515).

Materials and methods: Participants aged ≥18 years with BMI ≥30 or ≥27 kg/m2 with ≥1 obesity complication without T2D were randomized 1:1:1 to double-blind, once-weekly, subcutaneous injections of survodutide (up-titrated to 3.6 …