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Copyright And Political Campaigns: How Much Control Should A Copyright Owner Have Over The Use Of Their Musical Work In A Political Campaign, Jared Zim Jun 2023

Copyright And Political Campaigns: How Much Control Should A Copyright Owner Have Over The Use Of Their Musical Work In A Political Campaign, Jared Zim

University of Miami Business Law Review

Music often tells a powerful story, driving emotional connections. As a result, politicians rely on music in every aspect of their political campaigns from political advertisements to campaign rallies. There is a long history of such political uses of music, often without an artist’s permission. While most disputes over such uses have ended in either settlement or the campaign stopping use of the infringed work, former President Donald Trump’s unauthorized use of music on the campaign trail sparked countless artist complaints. The complaining musicians feared any implication that they endorsed Trump and did not want any association with a political …


Brain Pathway Identified That Impairs Postpartum Social Behavior After Adolescent Stress, Jeff Hansen Jun 2023

Brain Pathway Identified That Impairs Postpartum Social Behavior After Adolescent Stress, Jeff Hansen

Browse All News

No abstract provided.


The Reflective Administrator: A Leader-Centered Focus | Chapter 5. Reflection As Mindfulness, Angela Pool-Funai, Tony E. Summers Jun 2023

The Reflective Administrator: A Leader-Centered Focus | Chapter 5. Reflection As Mindfulness, Angela Pool-Funai, Tony E. Summers

Sociology Faculty Publications

This chapter will revisit some of the theories introduced in Ch. 1 and take the reader from the concept of a cycle in which reflection is a step toward a spiral or ongoing process. Reflective practice is not a standalone concept; on the contrary, it contributes to organizational culture. Adopting a mindfulness aptitude can help to develop an awareness of, and appreciation for, creativity within the public sector workplace. This, in turn, opens opportunities for reflective practice through action research and other means.


Regulating Best Interest: Sec Confronts The Brave New Markets, Rayaan Hossain Jun 2023

Regulating Best Interest: Sec Confronts The Brave New Markets, Rayaan Hossain

University of Miami Business Law Review

This Note comments on how recent developments in securities regulation deal with today’s securities industry challenges. As usual, the law advances much slower than technology. After decades of debate over heightened standards for broker-dealers giving investment advice, the Securities and Exchange Commission (“SEC”) introduced Regulation Best Interest (Reg BI). Our modern market demands that broker-dealers execute quick trades on behalf of their clients as well as provide broader investment advice. The popularity of online trading platforms (“OTPs”) only exacerbated the need for regulatory changes. The theme of this paper surmises how Reg BI responds to the rise of the retail …


Impact Of Advanced Trauma Life Support Training For Improving Mortality Outcome: A Systematic Review And Meta-Analysis, Afid B. Putra, Luthfian A. Nurachman, Bagus A. Suryawiditya, Muftah Risyaldi, Lam Sihardo Jun 2023

Impact Of Advanced Trauma Life Support Training For Improving Mortality Outcome: A Systematic Review And Meta-Analysis, Afid B. Putra, Luthfian A. Nurachman, Bagus A. Suryawiditya, Muftah Risyaldi, Lam Sihardo

The New Ropanasuri Journal of Surgery

Introduction. The Global Burden of Disease Study has identified injuries as one of the top ten causes of death and disability worldwide. Injury is predicted to rise in the rankings by the year 2030. This study aimed to quantify the effectiveness of an Advanced Trauma Life Support (ATLS) training in improving mortality outcome after trauma injury.

Method. This is a systematic review (of experimental and observational studies) and meta-analysis, reporting mortality outcome from trauma injury between ATLS-trained/certified physicians vs non-ATLS-certified. We performed literature searching through 3 electronic databases, including Cochrane (CENTRAL), MEDLINE (PubMed), and Scopus.

Results. There are summarized results …


Reviving The Gobbet: Venerable Sophistication For Contemporary Media Literacy, Kevin Hora Jun 2023

Reviving The Gobbet: Venerable Sophistication For Contemporary Media Literacy, Kevin Hora

Irish Journal of Academic Practice

This paper suggests that a technique for close textual reading used in history, the classics and theology for two almost two centuries, the gobbet, can be repurposed as a method of developing media literacy in higher education students in other disciplines. The gobbet is a bite-sized extract from a longer set text learners have studied that acts as an entry to the whole text, permitting critical, contextualised evaluation to take place. As a pedagogical tool, the gobbet can be a counterweight to discontinuous reading practices and abstracted information sources. It is highly effective for analysing contemporary media and discourse, in …


Gardner-Webb Announces New Vice President For Finance And Administration, Office Of University Communications Jun 2023

Gardner-Webb Announces New Vice President For Finance And Administration, Office Of University Communications

Gardner-Webb NewsCenter Archive

Officials at Gardner-Webb have named a new vice president for Finance and Administration—Mike Whiteman. He has 15 years of experience in higher education and his background includes work in public accounting, insurance and non-profit industries. He begins his duties at the University on July 24 and will report directly to GWU President Dr. William M. Downs.


Assessing The Language Of 2-Year-Olds: From Theory To Practice, Emily Jackson, Dani Levine, Jill De Villiers, Aquiles Iglesias, Kathy Hirsh-Pasek, Roberta Michnick Golinkoff Jun 2023

Assessing The Language Of 2-Year-Olds: From Theory To Practice, Emily Jackson, Dani Levine, Jill De Villiers, Aquiles Iglesias, Kathy Hirsh-Pasek, Roberta Michnick Golinkoff

Philosophy: Faculty Publications

Early screening for language problems is a priority given the importance of language for success in school and interpersonal relationships. The paucity of reliable behavioral instruments for this age group prompted the development of a new touchscreen language screener for 2-year-olds that relies on language comprehension. Developmental literature guided selection of age-appropriate markers of language disorder risk that are culturally and dialectally neutral and could be reliably assessed. Items extend beyond products of linguistic knowledge (vocabulary and syntax) and tap the process by which children learn language, also known as fast mapping. After piloting an extensive set of items (139), …


Supply Chain Disruptors And Their Impact On The Future Of Manufacturing, Logistics, And Distribution, Henk M. Zijm, Sunderesh S. Heragu Jun 2023

Supply Chain Disruptors And Their Impact On The Future Of Manufacturing, Logistics, And Distribution, Henk M. Zijm, Sunderesh S. Heragu

16th IMHRC Proceedings (Dresden, Germany- 2023)

In this paper, we outline some of the changes occurring in the world and how businesses are adapting to these changes. We also list disruptors – factors or new ideas that disrupt the status quo – and their impact on manufacturing, supply chain, logistics, and distribution.


Evaluating Business Service Models For On-Demand Warehousing: A Double Perspective On Suppliers And Customers, Maria Grazia Gnoni, Fabiana Tornese Jun 2023

Evaluating Business Service Models For On-Demand Warehousing: A Double Perspective On Suppliers And Customers, Maria Grazia Gnoni, Fabiana Tornese

16th IMHRC Proceedings (Dresden, Germany- 2023)

The on-demand warehousing model is emerging as a logistic solution based on resource sharing for businesses needing storage space. This model provides a business-to-business marketplace where companies can provide (or request) storage and other logistic services with a high level of flexibility. However, literature is still scarce on the topic, and while the potential advantages of such model are quite clear, its main criticalities need to be explored. Based on a market analysis of platforms currently providing on-demand warehousing opportunities, this work present a first discussion on the advantages and limitations of the model for customers and lenders.


Let Shoppers Shop: Why Click And Collect Is Not The Solution, Jennifer A. Pazour, Kai Furmans Jun 2023

Let Shoppers Shop: Why Click And Collect Is Not The Solution, Jennifer A. Pazour, Kai Furmans

16th IMHRC Proceedings (Dresden, Germany- 2023)

Buy-Online-Pickup-In-Store (BOPIS), also known as Click-and-Collect, are services where customers place their orders online and then travel to pick up their requested items at a pre-determined local location. This provides convenience to shoppers and eliminates the retailer’s last-mile delivery costs associated with home delivery. Yet, such omnichannel services shift the responsibility for the order fulfillment process to the retailer, whereas with in-store shoppers, the order fulfillment task is completed by shoppers themselves. Further, because of customers’ short response time expectations, it is typically infeasible for a retailer to conduct this order fulfillment process for click-and-collect orders at distribution centers located …


On Logistics And Motion Planning - An Informal Axiomatic Approach, Moritz Roidl Jun 2023

On Logistics And Motion Planning - An Informal Axiomatic Approach, Moritz Roidl

16th IMHRC Proceedings (Dresden, Germany- 2023)

Through the introduction of an informal axiomatic framework, this paper aims to contribute to the development of a general theory of logistics, which is currently still a blindspot in logistics research. It aims to combine the precision of robotic motion planning concepts with established logistics terminology, forging a link that balances the robustness of a mathematically rigorous theory with the rich semantic understanding inherent in logistics models. Centered around the notion of designing a logistic space, a possible way of structuring this space by grid-based and continuous spatial structures is discussed. The axiomatic framework is extended to include a new …


Requirements For Generating Learning Environments For Autonomous Systems Behavior In A Digital Continuum, Anike Murrenhoff Jun 2023

Requirements For Generating Learning Environments For Autonomous Systems Behavior In A Digital Continuum, Anike Murrenhoff

16th IMHRC Proceedings (Dresden, Germany- 2023)

Autonomous systems in material handling are increasingly prevalent in logistics, offering benefits such as flexibility, adaptability, robustness, and sustainability. To fully harness these advantages, a novel paradigm, the Digital Continuum, is proposed for the development and operation of such systems. A critical component of the Digital Continuum is a deeply integrated digital system model, which serves as a simulation, training, and test environment for virtual agents corresponding to physical robots. To ensure robust performance in learned behavior, a large number of learning environments is needed, thus highlighting the importance of an automated generation process. This process can significantly reduce modeling …


Front Matter And Table Of Contents Jun 2023

Front Matter And Table Of Contents

University of Miami Business Law Review

No abstract provided.


Workplace Traumatic Stress And Mental Health Sequelae Among Public Safety Telecommunications Officers In Florida, Kellie O'Dare, Tammie M. Johnson, Erin A. King, Joseph Herzog, Dana R. Dillard, Kimberley Powell, Arthur R. Kirby, Leah Atwell Jun 2023

Workplace Traumatic Stress And Mental Health Sequelae Among Public Safety Telecommunications Officers In Florida, Kellie O'Dare, Tammie M. Johnson, Erin A. King, Joseph Herzog, Dana R. Dillard, Kimberley Powell, Arthur R. Kirby, Leah Atwell

Florida Public Health Review

Background: Public safety telecommunications officers (PSTCOs), aka emergency “dispatchers,” are exposed to workplace traumatic stress and can experience situations characterized by uncertainty, communication difficulties, and a lack of resources. Traumatic stress experienced by emergency dispatchers has led to mental health symptoms. Purpose: This paper aims to describe the results of a study examining the patterns of workplace traumatic stress and the relationship between workplace traumatic stress and mental health concerns among a sample of PSTCOs. Methods: PSTCOs (n=54) participated in a cross-sectional, anonymous survey including screeners for depression, anxiety, post-traumatic stress disorder (PTSD), suicidal thoughts, and harmful alcohol use. …


England’S Early Years Foundation Stage (Eyfs) Framework: Towards A Minor Literature, Claire Walsh Jun 2023

England’S Early Years Foundation Stage (Eyfs) Framework: Towards A Minor Literature, Claire Walsh

School of Law, Humanities and Social Sciences

In the mid 1970s, the philosopher Gilles Deleuze and psychoanalyst Felix Guattari radically conceptualised the novelist Kafka in terms of marginal subjectivity. Their book, “Kafka: towards a minor literature” (1975/1986) was a consideration of minor thought as “an agent of transformative experimentation and collective awareness” (El Moncef, 2020) within a major language. Considering such agency, this paper, nearly fifty years on from Kafka, looks to extend our gaze beyond Deleuze and Guattari’s original theory towards ‘the people [who] are missing’ (Deleuze, 1989) - the minor readers. Evolving the concept of the marginal, the paper considers the major language of statutory …


Fabric-Based Organic Electrochemical Transistor Towards Wearable Ph Sensing Electronics, Nestor Osvaldo Marquez Rios Jun 2023

Fabric-Based Organic Electrochemical Transistor Towards Wearable Ph Sensing Electronics, Nestor Osvaldo Marquez Rios

USF Tampa Graduate Theses and Dissertations

Wearable electronics interest has attracted the attention of a few sectors because of their applicability in different areas like healthcare, military, and our daily basis. Still building circuits on fabrics to make these wearable electronics is challenging. As transistors are the building blocks of electronic circuits and most of the biosensors, recently, fiber-shaped electrochemical transistors have been studied extensively for a lot of applications including bioelectronics. Fiber-based devices are getting popular in different applications due to their low fabrication cost, lightweight, and flexibility without losing their properties. Additionally, they are potentially suitable for making sensors on garments.

In this work, …


Computational Fluid Dynamics Modeling Of A Wafer Etch Temperature Control System, Henrique Oyama, Kip Nieman, Anh Tran, Bernard Keville, Yewei Wu, Helen Durand Jun 2023

Computational Fluid Dynamics Modeling Of A Wafer Etch Temperature Control System, Henrique Oyama, Kip Nieman, Anh Tran, Bernard Keville, Yewei Wu, Helen Durand

Chemical Engineering and Materials Science Faculty Research Publications

Next-generation etching processes for semiconductor manufacturing exploit the potential of a variety of operating conditions, including cryogenic conditions at which high etch rates of silicon and very low etch rates of the photoresist are achieved. Thus, tight control of wafer temperature must be maintained. However, large and fast changes in the operating conditions make the wafer temperature control very challenging to be performed using typical etch cooling systems. The selection and evaluation of control tunings, material, and operating costs must be considered for next-generation etching processes under different operating strategies. These evaluations can be performed using digital twin environments (which …


Church Music Leaders In The Usa: Prioritizing Technical Competence And Inclusion, Heather Maclachlan Jun 2023

Church Music Leaders In The Usa: Prioritizing Technical Competence And Inclusion, Heather Maclachlan

Department of Music Faculty Publications

Church music leaders in the United States pursue two priorities: technical accuracy and fluency in the music-making of their church ensembles, and, including as many volunteers as possible in those same ensembles. At times, the prioritization of technical competence and inclusion conflict, because volunteers whose playing or singing is less than competent seek to be included in church music groups. Facing this ethical dilemma, church music leaders operate ethically; that is, they employ strategies and develop policies based on their understanding of their responsibilities to other people (Warren 2014). During interviews, they verbally espouse an ethic of deontology, but in …


Analysis Of Ostds Failure Potential Due To Sea-Level Rise And Other Inundation Factors: An Integrated Geo-Spatial Analysis, Alec Colarusso Jun 2023

Analysis Of Ostds Failure Potential Due To Sea-Level Rise And Other Inundation Factors: An Integrated Geo-Spatial Analysis, Alec Colarusso

USF Tampa Graduate Theses and Dissertations

While many aspects of climate change are well-studied, the vulnerability of Onsite Sewage Treatment and Disposal Systems (OSTDS) to sea-level rise (SLR) has not been thoroughly examined despite the potentially significant environmental impacts, including nutrient and pathogen loading. Research gaps include the need to determine the suitability of models to predict groundwater inundation due to SLR and the consequent impact on OSTDS. As such, this study aims to compare Bathtub/hydrostatic and physics-based/MODFLOW/3D numerical modeling methods of simulating groundwater inundation from SLR to identify OSTDS vulnerability to failure due to a reduction in the height of the vadose zone (saturation or …


2023-June-23-Etsu Spring 2023 Dean's List, University Marketing And Communication, East Tennessee State University Jun 2023

2023-June-23-Etsu Spring 2023 Dean's List, University Marketing And Communication, East Tennessee State University

ETSU News

(June 23, 2023) East Tennessee State University has announced the names of students who attained a grade point average qualifying them for inclusion in the dean’s list for spring 2023. 

To receive this honor, undergraduate students must pass a minimum of 12 credits (excluding audits, incompletes, repeats and pass/fail) with no grade below B- in any course taken, and a grade point average of at least 3.5 on a 4.0 scale. Students from the Bill Gatton College of Pharmacy must successfully complete a minimum of 12 hours and earn a grade point average of at least 3.5 or above with …


A Collaborative And Near‑Comprehensive North Pacifc Humpback Whale Photo‑Id Dataset, T. Cheeseman, Ken Southerland, Jo Marie Acebes, Katherina Audley, Jay Barlow, Lars Bejder, Caitlin Birdsall, Amanda L. Bradford, Josie K. Byington, John Calambokidis, Rachel Cartwright, Jen Cedarleaf, Andrea Jacqueline García Chavez, Jens J. Currie, JoëLle De Weerdt, Nicole Doe, Thomas Doniol‑Valcroze, Karina Dracott, Olga Filatova, Rachel Finn, Kiirsten Flynn, John K. Ford, Astrid Frisch‑Jordán, Christine M. Gabriele, Beth Goodwin, Craig Hayslip, Jackie Hildering, Marie C. Hill, Jeff K. Jacobsen, M. Esther Jiménez‑López Jun 2023

A Collaborative And Near‑Comprehensive North Pacifc Humpback Whale Photo‑Id Dataset, T. Cheeseman, Ken Southerland, Jo Marie Acebes, Katherina Audley, Jay Barlow, Lars Bejder, Caitlin Birdsall, Amanda L. Bradford, Josie K. Byington, John Calambokidis, Rachel Cartwright, Jen Cedarleaf, Andrea Jacqueline García Chavez, Jens J. Currie, JoëLle De Weerdt, Nicole Doe, Thomas Doniol‑Valcroze, Karina Dracott, Olga Filatova, Rachel Finn, Kiirsten Flynn, John K. Ford, Astrid Frisch‑Jordán, Christine M. Gabriele, Beth Goodwin, Craig Hayslip, Jackie Hildering, Marie C. Hill, Jeff K. Jacobsen, M. Esther Jiménez‑López

Faculty, Staff, and Students

We present an ocean-basin-scale dataset that includes tail fuke photographic identifcation (photo-ID) and encounter data for most living individual humpback whales (Megaptera novaeangliae) in the North Pacifc Ocean. The dataset was built through a broad collaboration combining 39 separate curated photo-ID catalogs, supplemented with community science data. Data from throughout the North Pacifc were aggregated into 13 regions, including six breeding regions, six feeding regions, and one migratory corridor. All images were compared with minimal pre-processing using a recently developed image recognition algorithm based on machine learning through artifcial intelligence; this system is capable of rapidly detecting matches between individuals …


A Collaborative And Near-Comprehensive North Pacific Humpback Whale Photo-Id Dataset, T. Cheeseman, Ken Southerland, Jo Marie Acebes, Katherina Audley, Jay Barlow, Lars Bejder, Caitlin Birdsall, Amanda L. Bradford, Josie K. Byington, John Calambokidis, Rachel Cartwright, Jen Cedarleaf, Andrea Jacqueline García Chavez, Jens J. Currie, JoëLle De Weerdt, Nicole Doe, Thomas Doniol‑Valcroze, Karina Dracott, Olga Filatova, Rachel Finn, Kiirsten Flynn, John K. Ford, Astrid Frisch‑Jordán, Christine M. Gabriele, Beth Goodwin, Craig Hayslip, Jackie Hildering, Marie C. Hill, Jeff K. Jacobsen, M. Esther Jiménez‑López Jun 2023

A Collaborative And Near-Comprehensive North Pacific Humpback Whale Photo-Id Dataset, T. Cheeseman, Ken Southerland, Jo Marie Acebes, Katherina Audley, Jay Barlow, Lars Bejder, Caitlin Birdsall, Amanda L. Bradford, Josie K. Byington, John Calambokidis, Rachel Cartwright, Jen Cedarleaf, Andrea Jacqueline García Chavez, Jens J. Currie, JoëLle De Weerdt, Nicole Doe, Thomas Doniol‑Valcroze, Karina Dracott, Olga Filatova, Rachel Finn, Kiirsten Flynn, John K. Ford, Astrid Frisch‑Jordán, Christine M. Gabriele, Beth Goodwin, Craig Hayslip, Jackie Hildering, Marie C. Hill, Jeff K. Jacobsen, M. Esther Jiménez‑López

Faculty, Staff, and Students

We present an ocean‑basin‑scale dataset that includes tail fluke photographic identification (photo‑ID) and encounter data for most living individual humpback whales (Megaptera novaeangliae) in the North Pacific Ocean. The dataset was built through a broad collaboration combining 39 separate curated photo‑ID catalogs, supplemented with community science data. Data from throughout the North Pacific were aggregated into 13 regions, including six breeding regions, six feeding regions, and one migratory corridor. All images were compared with minimal pre‑processing using a recently developed image recognition algorithm based on machine learning through artificial intelligence; this system is capable of rapidly detecting matches between individuals …


Understanding Computational Thinking In The Gameplay Of The African Songo Board Game, Rebecca Y. Bayeck Jun 2023

Understanding Computational Thinking In The Gameplay Of The African Songo Board Game, Rebecca Y. Bayeck

Instructional Technology and Learning Sciences Faculty Publications

Computational thinking is a necessary skill for the 21st century. While previously examined in computer-rich settings, researchers are increasingly studying computational thinking in unplugged environments such as board games. Focusing on the African board game Songo, this study shows that computational thinking practices are embedded in Songo board gameplay and interact with the cultural context. The study also reveals a computing practice peculiar to Songo gameplay, songoputation. This paper suggests that researchers can benefit from exploring computational thinking and computing practices beyond board games in western contexts.


Skull Scare, Beth Potier Jun 2023

Skull Scare, Beth Potier

UNH Today Archive

No abstract provided.


A Qualitative Study Of Facilitators And Barriers Perceived By Black Students And Their Effect On Advanced Placement Course Enrollment In High School, Austin R. Cole Jun 2023

A Qualitative Study Of Facilitators And Barriers Perceived By Black Students And Their Effect On Advanced Placement Course Enrollment In High School, Austin R. Cole

USF Tampa Graduate Theses and Dissertations

Advanced Placement (AP) classes can provide many benefits to students. The rigorous curriculum gives students an academic challenge to expand their educational abilities (The College Board, 2014). However, students of color are often underrepresented in AP participation (The College Board, 2014). Research has investigated factors among students of color that predict participation and success in AP courses, suggesting that family SES and prior academic achievement (Dixson et al., 2017; Ndura et al., 2003), and racial barriers impact students’ ability to choose to take AP courses (Jeffries & Silvernail, 2017; Walker & Pearsall, 2012). This study addressed a gap in the …


Staff Council Minutes, Georgia Southern University Jun 2023

Staff Council Minutes, Georgia Southern University

Staff Council Meeting Minutes & Agendas

No abstract provided.


Staff Council Agenda, Georgia Southern University Jun 2023

Staff Council Agenda, Georgia Southern University

Staff Council Meeting Minutes & Agendas

No abstract provided.


An Erk5-Nrf2 Axis Mediates Senescence-Associated Stemness And Atherosclerosis, Jun-Ichi Abe, Masaki Imanishi, Shengyu Li, Aijun Zhang, Kyung Ae Ko, Venkata S K Samanthapudi, Ling-Ling Lee, Angelica Paniagua Bojorges, Young Jin Gi, Brian P Hobbs, Anita Deswal, Joerg Herrmann, Steven H Lin, Eduardo N Chini, Ying H Shen, Keri L Schadler, Thi-Hong-Minh Nguyen, Anisha A Gupte, Cielito Reyes-Gibby, Sai-Ching J Yeung, Rei J Abe, Elizabeth A Olmsted-Davis, Sunil Krishnan, Robert Dantzer, Nicolas L Palaskas, John P Cooke, Henry J Pownall, Momoko Yoshimoto, Keigi Fujiwara, Dale J Hamilton, Jared K Burks, Guangyu Wang, Nhat-Tu Le, Sivareddy Kotla Jun 2023

An Erk5-Nrf2 Axis Mediates Senescence-Associated Stemness And Atherosclerosis, Jun-Ichi Abe, Masaki Imanishi, Shengyu Li, Aijun Zhang, Kyung Ae Ko, Venkata S K Samanthapudi, Ling-Ling Lee, Angelica Paniagua Bojorges, Young Jin Gi, Brian P Hobbs, Anita Deswal, Joerg Herrmann, Steven H Lin, Eduardo N Chini, Ying H Shen, Keri L Schadler, Thi-Hong-Minh Nguyen, Anisha A Gupte, Cielito Reyes-Gibby, Sai-Ching J Yeung, Rei J Abe, Elizabeth A Olmsted-Davis, Sunil Krishnan, Robert Dantzer, Nicolas L Palaskas, John P Cooke, Henry J Pownall, Momoko Yoshimoto, Keigi Fujiwara, Dale J Hamilton, Jared K Burks, Guangyu Wang, Nhat-Tu Le, Sivareddy Kotla

Faculty, Staff and Student Publications

BACKGROUND: ERK5 (extracellular signal-regulated kinase 5) is a dual kinase transcription factor containing an N-terminal kinase domain and a C-terminal transcriptional activation domain. Many ERK5 kinase inhibitors have been developed and tested to treat cancer and inflammatory diseases. However, recent data have raised questions about the role of the catalytic activity of ERK5 in proliferation and inflammation. We aimed to investigate how ERK5 reprograms myeloid cells to the proinflammatory senescent phenotype, subsequently leading to atherosclerosis.

METHODS: A ERK5 S496A (dephosphorylation mimic) knock in (KI) mouse model was generated using CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/clustered regularly interspaced short palindromic …


Variation In Salamander Life History And Community Composition Across An Urban Gradient In Atlanta, Georgia, Usa, Leah Rittenburg Jun 2023

Variation In Salamander Life History And Community Composition Across An Urban Gradient In Atlanta, Georgia, Usa, Leah Rittenburg

Master of Science in Integrative Biology Theses

Urbanization threatens to alter stream systems in watersheds in the eastern United States. These highly disturbed systems may result in many local extirpations of sensitive salamander species. One group of organisms that often persists in urban streams is the Eurycea bislineata (Two-lined Salamander) species complex. Many aspects of Two-lined Salamander life history are linked to environmental factors, particularly stream temperature, prey abundance, and stream hydrology. Urbanization threatens to alter these environmental factors, potentially influencing Two-lined Salamander life history. At 14 sites spanning an urban gradient in Atlanta, GA, I investigated the variation in life history and phenology in the Southern …