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Articles 9661 - 9690 of 732788
Full-Text Articles in Entire DC Network
2026 Sullivan County 4-H Presents, Lynn Brewer
2026 Sullivan County 4-H Presents, Lynn Brewer
UNH Cooperative Extension
No abstract provided.
Sc 4-H Presents Information Packet, Lynn Brewer
Sc 4-H Presents Information Packet, Lynn Brewer
UNH Cooperative Extension
No abstract provided.
Albumin-Binding Domains In Therapeutic Protein Engineering: A Structural And Computational Perspective On Rational Design, Matthew Argyle, Dallin M. Chipman, Anna Claire Woolley, Bradley C. Bundy, Dennis Della Corte
Albumin-Binding Domains In Therapeutic Protein Engineering: A Structural And Computational Perspective On Rational Design, Matthew Argyle, Dallin M. Chipman, Anna Claire Woolley, Bradley C. Bundy, Dennis Della Corte
Faculty Publications
Therapeutic proteins face a critical pharmacokinetic challenge: rapid clearance from circulation limits their clinical efficacy. Albumin-binding domains (ABDs) offer an elegant solution by enabling therapeutic proteins to “hitchhike” on serum albumin’s favorable 19-day half-life through FcRn-mediated recycling. Clinical validation through approved therapeutics like ozoralizumab demonstrates the success of this approach, with preclinical studies showing fusion to an ABD extended half-life to 18 days. This review provides an analysis of ABD-fusion protein design, integrating structural biology, computational prediction, and rational engineering principles. We catalog the major classes of albumin-binding modalities, including bacterial three-helix bundle domains, engineered peptides, antibody-derived binders, and alternative …
Tell Me Again Who Are You?, Heather Sellers
Tell Me Again Who Are You?, Heather Sellers
Creative Nonfiction Magazine
No abstract provided.
Notes On The Space We Take, Bonnie J. Rough
Notes On The Space We Take, Bonnie J. Rough
Creative Nonfiction Magazine
No abstract provided.
Wild Flavor, Karl Taro Greenfield
North Pole, South Pole, The Sea Of Carcinoma, Dev Hathaway
North Pole, South Pole, The Sea Of Carcinoma, Dev Hathaway
Creative Nonfiction Magazine
No abstract provided.
Thirteen More Ways Of Looking At A Blackbird, Dorie Bargmann
Thirteen More Ways Of Looking At A Blackbird, Dorie Bargmann
Creative Nonfiction Magazine
No abstract provided.
Job No. 51 - Executive Director And Job No. 52 - Psychic Medium, Oliverdavies .Blogspot.Com
Job No. 51 - Executive Director And Job No. 52 - Psychic Medium, Oliverdavies .Blogspot.Com
Creative Nonfiction Magazine
No abstract provided.
The Truth About Cops And Dogs, Rebecca Skloot
The Truth About Cops And Dogs, Rebecca Skloot
Creative Nonfiction Magazine
No abstract provided.
Consumption, Sunshine O'Donnell
'Mbriago, Louise Desalvo
The Cipher In Room 214: Who Was Mary Anderson Why Did She Die?, Carol Smith
The Cipher In Room 214: Who Was Mary Anderson Why Did She Die?, Carol Smith
Creative Nonfiction Magazine
No abstract provided.
Netting The Future, Donna Seaman
The Library As Storyplace, Rebecca T. Miller
The Library As Storyplace, Rebecca T. Miller
Creative Nonfiction Magazine
No abstract provided.
Mama, Che Cosa Vuoi Che Faccio?, James Vescovi
Mama, Che Cosa Vuoi Che Faccio?, James Vescovi
Creative Nonfiction Magazine
No abstract provided.
Dagos In Mayberry, Peter Selgin
'Mbriago, Louise Desalvo
Temporal Dynamics Of Irrigation Characteristics In South Carolina, Selvalakshmi Selvaraj, Jose O. Payero, Dana B. Turner
Temporal Dynamics Of Irrigation Characteristics In South Carolina, Selvalakshmi Selvaraj, Jose O. Payero, Dana B. Turner
Journal of South Carolina Water Resources
Irrigation plays a vital role in stabilizing crop production under climatic variability in the southeastern United States. However, limited long-term empirical evidence exists on how irrigation practices, water sources, and energy demands have evolved in South Carolina. The aim of this study was to examine temporal changes in irrigation characteristics in South Carolina. The analysis utilized two decades (2003–2023) of data from the United States Department of Agriculture – National Agricultural Statistics Service, Irrigation and Water Management Surveys. Results showed a 65% increase in the number of irrigated farms and 260% expansion in irrigated acreage over the twenty-year period. Groundwater …
Mountaineer, Craig Bernier
Without A Map, Meredith Hall
From “A Writer’S Life”, Gay Talese
Style-Preserved Inference Flow (Spif): Real-Time Style-Locked Image Generation Through Model Pruning And Latent Space Optimization, Douglass W. Sharp
Style-Preserved Inference Flow (Spif): Real-Time Style-Locked Image Generation Through Model Pruning And Latent Space Optimization, Douglass W. Sharp
Defensive Publications Series
This publication discloses Style-Preserved Inference Flow (SPIF), a system for real-time style-locked image generation that maintains consistent artistic style across frames at interactive rates. The core innovation is structural model pruning guided by style-consistency metrics rather than general image quality, producing compact single-purpose models that generate images in a specific artistic style at 60+ frames per second. Additional disclosed techniques include latent-space frame coherence (bootstrapping sequential frames from previous latent states, analogous to dirty-rectangle optimization in game rendering), composable latent object descriptors for real-time scene manipulation, and voice-driven continuous generation loops. Working prototypes demonstrate 3.35 FPS full-pipeline generation at 1024×1024 …
Tiny But Moral: How "The Adventures Of Little Tiny And The White Mouse" Portrays Children’S Moral And Social Responsibilities In The Civil War Era, Abigail Hagopian
Tiny But Moral: How "The Adventures Of Little Tiny And The White Mouse" Portrays Children’S Moral And Social Responsibilities In The Civil War Era, Abigail Hagopian
CAFE Symposium 2026
Estimated to have been published between 1860 and 1866, The Adventures of Little Tiny and the White Mouse was one of many works for children published by Thomas W. Strong in New York during the American Civil War. The eight-page picture book examines morality and consequences through the misfortunate adventures of a young, yet moral, abnormally small boy named Little Tiny. The youngest of a Broom Maker’s three sons, Tiny’s jealous older brothers sell him to a circus, where he performs alongside a myriad of animals. Missing his father, the animals jump through a series of hoops to help Tiny …
An Expedition To Public Lands: Exploring The Black Hills Region, John Mcdermott
An Expedition To Public Lands: Exploring The Black Hills Region, John Mcdermott
CAFE Symposium 2026
This project explores 4 public land sites in southwestern South Dakota: Badlands National Park, Mount Rushmore National Memorial, Black Hills National Forest, and Lacreek National Wildlife Refuge. I researched each site's most popular recreation activities and contributions to American history, as well as economic data that shows the difference in management strategies between the National Park Service and the US Forest Service.
The Future Of West African Cacao Farming, Kathryn Lesniewski
The Future Of West African Cacao Farming, Kathryn Lesniewski
CAFE Symposium 2026
This poster covers the detrimental impact climate change has had on the West African cacao farming industry. It also covers long and short term solutions to climate change, and how the global chocolate market has been impacted by climate change.
Hercules In Myth And Animation: Masculinity And Heroism, Noah Bautista
Hercules In Myth And Animation: Masculinity And Heroism, Noah Bautista
CAFE Symposium 2026
Disney's Hercules is a model man in today's society who combines the best aspects of both masculinity and femininity. In the myths, however, Hercules was much different and did not act as such a bridge between femininity and masculinity at the time. Through other scholarly works, the way that masculinity, heroism, and instrumentalization are presented and used is examined. Mythological Herakles is found to be a much more aggressive archetype of a man rather than Hercules, who is based upon strength in moderation and a more social society. Each fit into the ideals of the society they come from, perpetuating …
Unprotected: The Lack Of Legal Safeguards For Child Entertainers, Paul Simpson
Unprotected: The Lack Of Legal Safeguards For Child Entertainers, Paul Simpson
Loyola of Los Angeles Entertainment Law Review
No abstract provided.
High-Quality Mouse Reference Genomes Reveal The Structural Complexity Of The Murine Protein-Coding Landscape., Mohab Helmy, Jin U Li, Xinyu F Yan, Rachel K Meade, Elizabeth Anderson, Patrick B Chen, Anne M Czechanski, Tomás Di Domenico, Jonathan Flint, Erik Garrison, Marco T P Gontijo, Andrea Guarracino, Leanne Haggerty, Edith Heard, Kerstin Howe, Narendra Meena, Fergal J Martin, Eric A Miska, Isabell Rall, Navin B Ramakrishna, Alexandra Sapetschnig, Swati Sinha, Diandian Sun, Francesca F Tricomi, Runjia Qu, Jonathan M D Wood, Tianzhen Wu, Dian J Zhou, Laura G Reinholdt, David J Adams, Clare M Smith, Jingtao Lilue, Thomas M Keane
High-Quality Mouse Reference Genomes Reveal The Structural Complexity Of The Murine Protein-Coding Landscape., Mohab Helmy, Jin U Li, Xinyu F Yan, Rachel K Meade, Elizabeth Anderson, Patrick B Chen, Anne M Czechanski, Tomás Di Domenico, Jonathan Flint, Erik Garrison, Marco T P Gontijo, Andrea Guarracino, Leanne Haggerty, Edith Heard, Kerstin Howe, Narendra Meena, Fergal J Martin, Eric A Miska, Isabell Rall, Navin B Ramakrishna, Alexandra Sapetschnig, Swati Sinha, Diandian Sun, Francesca F Tricomi, Runjia Qu, Jonathan M D Wood, Tianzhen Wu, Dian J Zhou, Laura G Reinholdt, David J Adams, Clare M Smith, Jingtao Lilue, Thomas M Keane
Faculty Research 2026
We present a collection of 17 high-quality long-read inbred mouse strain genomes with complete annotation (contig N50s of 0.8-33.9 Mbp). This collection includes 12 widely used classical laboratory strains and 5 wild-derived strains. We have resolved previously incomplete genomic regions, including the major histocompatibility complex (MHC), defensin cluster, T cell receptor, and Ly49 complexes. Hundreds of non-reference genes from previous publications not found in GRCm39, such as Defa1, Raet1a, and Klra20 (Ly49T), were localized in the new reference genomes. We conducted a genome-wide scan of variable number tandem repeats (VNTRs) within the coding regions, identifying over 400 genes with VNTR …