Digital Commons Network^™

Chronic Exercise And The Treatment Of Progressive Disorders, Kristin Ann Richardson

Wayne State University Dissertations

Exercise is a known, beneficial treatment for a variety of normal (aging) and abnormal (disease) declines in health. These benefits can be observed in a range of tissues, including the brain and muscle, and organelles, such as the mitochondria. Many of the mechanisms through which exercise can promote health in these contexts have recently come to light. However, how these mechanisms can be targeted to promote health in sedentary populations is still under investigation. In Drosophila, stimulation of octopaminergic neurons provides the benefits of endurance exercise to sedentary flies. Neuroplasticity following exercise is one possible mechanism for how octopaminergic activation …

Lanthanide-Based Responsive Contrast Agents For Magnetic Resonance Imaging, Md Mamunur Rashid

Wayne State University Dissertations

This thesis is a collection of seven chapters that discuss the contributions to the field oflanthanide-based contrast agents for magnetic resonance imaging (MRI), particularly in the context of imaging hypoxia and extracellular pH. These physiological changes play a significant role in life-threatening conditions such as cancer, making it essential to develop effective imaging tools to aid in diagnosis and treatment. The thesis provides insights for the rational development of lanthanide-based contrast agents for MRI. A comprehensive review of divalent europium as a tool for imaging hypoxia using magnetic resonance imaging and how coordination chemistry can be used to tune the …

Investigation Of Biomechanical Thresholds Of Mild To Severe Brain Injury Using An Anisotropic Visco-Hyperelastic Finite Element Head Model: Model Development And Simulation Of Impact Injury And Blast Injury, Ding Lyu

Wayne State University Dissertations

Traumatic Brain Injury (TBI) is a significant cause of death and disability in the United States, with approximately 2.5 million emergency department visits, 288,000 hospitalizations, and 56,800 deaths reported to be related to TBI. The majority of TBIs are caused by blunt impacts resulting from falls and motor vehicle crashes. The head injury criterion is the only standard used to assess the safety related to vehicles, personal protective gear, and sports equipment. A new brain injury criterion assessing rotation velocity effect was recently proposed by the US government. Unfortunately, it derivation from animal data scaled to a computer model of …

Meaningful Access To Justice For Customers In The Gig Economy, Andrea Jakubas

Chicago-Kent Law Review

No abstract provided.

Understanding Inflammation, Immunity, And Infection, Jeff Vasiloff, Md, Mph

OHIO Open Faculty Textbooks

Inflammation, immunity, and infection explained by Jeffrey Vasiloff, MD, MPH, Associate Clinical Professor, PA Program; Adjunct Professor, PT Program, College of Health Sciences and Professions, Ohio University Dublin Medical Campus; Physician Consultant: Ohio Association of Physician Assistants; Physician Volunteer: Franklin County & Columbus Medical Reserve Corps; Board Certification: Internal Medicine & Diabetes and Endocrinology.

Prg4/Cd44/Pp2a Signaling Axis: A Significant Regulator Of Gout Arthritis, Sandy Elsayed

Pharmaceutical Sciences (PhD) Dissertations

Introduction: Gout is a common chronic arthritis caused by monosodium urate (MSU) crystal deposition in joints leading to activation of synovial resident macrophages and downstream production of interleukin-1b (IL-1b). Xanthine oxidase (XO) catalyzes purines into uric acid (UA) and reactive oxygen species (ROS) that activate NLRP3 inflammasome. Protein phosphatase-2A (PP2A) may be involved in regulating inflammatory pathways in macrophages. Proteoglycan 4 (PRG4) and its receptor CD44 and its transducer PP2A signaling axis play a biologically significant role in regulating urate crystal inflammation.

Methods: Monocytes and macrophages were primed with TLR2 agonist and stimulated with MSU crystals. Fingolimod (PP2A …

The Impact Of Marginalization On Relations With Law Enforcement And The Criminal Justice System, Angelo Kevin Brown

Faculty Publications

This chapter provides an overview of how critical race theory (CRT) has provided an important context for the racial disparities in the criminal justice system. CRT has promoted teaching the history of the criminal justice system in the United States of America (USA) and abroad from a racial perceptive. CRT scholars emphasize race because of how race and racism have shaped and impacted our society and institutions. CRT has been used to understand issues from police violence, sentencing disparities, school-to-prison pipeline, prison abolitionism, and much more. The CRT framework is especially important when it comes to understanding the disparities and …

Bs Environmental Science, 2023-24, Arkansas State University - Jonesboro

Bachelor of Science and Education

No abstract provided.

Evaluating Food Metrics Of Lanternfishes In Waters Of The Southeastern Pacific Ocean, Carolina Carcamo, Pepe Espinoza, Carlos Canales-Cerro, Stephanny Curaz-Leiva, Ana Brisca Guzman-Castellanos, Ivonne Quintanilla, Fernanda Vargas, Mauricio Zuñiga, Francisco Fernandoy, Patricio Galvez, Rene Vargas, Álvaro Saavedra, Chris Harrod, Eric T. Schultz, Sebastian Klarian

EEB Articles

Using carbon and nitrogen stable isotope values, we analyzed the trophic position (TP) and the isotopic niche width of lanternfishes from three different areas in the Southern Pacific Ocean. Fishes from Perú had slightly higher δ¹³C values compared with fish from Chilean areas. In contrast, δ¹⁵N values increased with latitude (North to South). Myctophids TP differed between the three study areas (highest in Central Chile, lowest in Peru). Peruvian fishes had a smaller isotopic niche than the lanternfishes of those from Chile.

What Are You Doing Here? Unexpected Occurrences Of Knobfin Sculpins (Cottus Immaculatus) In Connecticut, Joshua M. Tellier, Brooke Winsmann, Michael Humphreys, Stella Minoudi, Alexandros Triantafyllidis, Eric T. Schultz

EEB Articles

Reductions in cold-water habitat owing to anthropogenic stressors are focusing attention on indicator fish species. We investigated an apparent range expansion in Connecticut of a native cold-water fish, Slimy Sculpin (Cottus cognatus). Unexpectedly, genetic and morphological analyses identified the new population as a non-native cottid from the Ozark region, the Knobfin Sculpin (C. immaculatus). This is the first record of C. immaculatus outside of its native range. The new occurrences were not recognized for over a decade despite comprehensive watershed inventories by state natural resource managers. The mechanism by which the non-native Knobfin Sculpin first arrived in Connecticut is currently …

Equal Protection Against Policing, Evan D. Bernick

College of Law Faculty Publications

A White police officer pins his knee against a Black man’s neck. The Black man lies prone. He says he can’t move. He says he can’t breathe. He says he’s through. He pleads for his mama. He moans, gasps, and writhes. Blood runs out of his nose and mouth. After eight minutes and forty-six seconds, George Floyd is dead.

Videos of the killing went viral. All four of the Minneapolis Police Department officers who arrested Floyd for allegedly using a counterfeit $20 bill at a convenience store were fired. Derek Chauvin—who held his knee to Floyd’s neck—was initially charged by …

Movement Administrative Procedure, Evan D. Bernick

College of Law Faculty Publications

On April 4, 1946, The Potters Herald, a Thursday weekly dedicated to labor and union news, published an editorial warning readers of pending legislation “which may seriously affect labor” despite not containing a “single word about labor” in its text. This legislation would empower “anti-labor judges” to overturn decisions by the National Labor Relations Board. Despite its neutral appearance, it was in reality designed to “kick [labor and the NLRB] in the teeth” and would result in “a field day for the corporation lawyers.”

The complained-of legislation was the Administrative Procedure Act of 1946 (APA). From today’s vantage point, the …

2022 Annual Town Report Fremont, New Hampshire, Fremont Town Representatives

Fremont, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

The Primacy Of Openness In Ecological Complexity Theory, Colby Clark

Theses and Dissertations--Philosophy

Five principles are at the foundation of complex systems theory: emergence, openness, contingency, historicity, and indeterminacy. Of those five, the principle of emergence is easily the most prevalent. Simply put, emergence refers to the idea that some wholes cannot be properly accounted for by appealing to individual explanations of the parts that compose it. In ecological complexity theory, the principle of emergence is strongly associated with the self-organizing feedbacks that often identify the structural framework of ecosystems.

Within the last half century, the intense focus on the principle of emergence has engendered the development of many conceptual distinctions that have …

Regulating The Digital Resonance, Hassan Salman

UC Law Science and Technology Journal

The proliferation of automated content moderation in social media has negatively impacted users’ (individuals, businesses, and governments) selfexpressions. Major social media platforms like Facebook act as public forums for billions of users whose content may vary in terms of acceptability and legality. User content is colored by social as well as personal norms, values and experiences. For example, though blasphemy may be objectionable in Poland, it may not be so in France. However, despite facing some mistrust over how Facebook and other platforms handle user data and moderate content, users rely on the entities like Facebook to correctly filter this …

Solar Farms In Georgia: Why We Need To Start Thinking About The End, Erica L. Welsh

Georgia State University Law Review

Despite the lack of a renewable energy mandate or a statewide carbon-cutting goal, Georgia’s renewable energy development, particularly utility-scale solar installations, is expected to increase exponentially. In the rush to join this renewable energy development surge, utilities, solar developers, and local governments must prudently consider how to manage this growth wisely and prevent avoidable costs in preparing for the inevitable decommissioning of these solar installations. Although Georgia is one of the nation’s leading states for solar power with its abundant land and sunshine, it lacks statewide policies addressing decommissioning concerns. A statewide decommissioning policy that requires some form of decommissioning …

Reducing Single-Use Plastic Waste: A Better Alternative To The Reduce Act Tax Proposal, Ryann Wong

UC Law Science and Technology Journal

This article will discuss the relevant and imminent need for government intervention to curb and reduce single-use plastic waste. It will look at the proposed 2019 REDUCE Act and consider potential outcomes and unintended consequences which the proposed plan may bring. The article will analyze the REDUCE Act through a discussion of: how similar policies have fared in the past, a historical survey of single-use plastics in US supply chain practices, how past tax laws have had a disproportionate impact on low-income taxpayers, the current market demands for single-use plastics, and an observation of how other countries are applying tax …

The Essence Of Therapeutic Relationships In Equine-Assisted Psychotherapy, Joy Clark Akin

Walden Dissertations and Doctoral Studies

AbstractTraditional psychotherapeutic approaches are not always effective in alleviating psychological symptoms and improving functioning in young adults. Equine-assisted psychotherapy (EAP) has been shown as a beneficial alternative therapeutic method developed for clients not helped by traditional methods. However, the essence of the therapeutic relationship that develops between the client, horse, therapist, and equine specialist has not been explored. The purpose of this phenomenological study was to explore the lived experience of the therapeutic relationship in young adults who participated in EAP. The frameworks of person-centered theory and self psychology guided the development of interview questions, data analysis, and interpretation. Four …

Perceptions Of Science Teachers At Title I Middle Schools Tasked To Integrate Digital Interactive Textbooks, April C. Carpenter

Walden Dissertations and Doctoral Studies

In the K-12 classrooms, science teachers are increasingly using digital interactive textbooks to improve instruction. However, limited research exists on the Title I science educators’ experiences with digital interactive texts in Title I middle schools. The purpose of this qualitative study was to explore the perceptions of these Title I science teachers in middle schools tasked with integrating digital interactive textbooks. This study was guided through the lens of Fuller’s stages of concern, a component of the Concerns Based Adoption Model (CBAM). Adopting basic qualitative methodology, purposeful sampling was employed to recruit nine Title I middle school science teachers through …

Teachers’ And Education Leaders’ Perspectives On Using Technology To Develop Vocabulary Among Kindergarten English Learners, Nelsy J. Jackson

Walden Dissertations and Doctoral Studies

AbstractResearch has shown that technology-mediated interventions in education can increase students’ understanding of academic vocabulary. However, it is not known how teachers provide opportunities for kindergarten English learners (ELs) to learn vocabulary using technology, and school leaders support teachers in this endeavor. The purpose of this basic qualitative study was to understand teachers' and school leaders’ perspectives on opportunities for kindergarten ELs to use technology to develop vocabulary in an urban school in the southwest United States. The theoretical framework for this study was based on Cummins’s theory of basic interpersonal communication skills and cognitive academic language proficiency. Using purposeful …

American Women's Motivations To Join Overseas Terrorist Groups, Zuri Sushil Birla

Walden Dissertations and Doctoral Studies

An increasing number of American women are actively engaging in overseas terrorist organizations and networks. Their motives, though, are little understood by researchers, although familial relationships and other associations, gender roles, and social media propaganda may play a role. The purpose of this qualitative narrative case study was to better understand the motives, decision-making, and behaviors of radicalized American women. The theoretical framework was social behavior theory and the research design, narrative case study based on Maslow’s Hierarchy of Needs and Motivation. The research question addressed American women’s immersion into terrorism through social media outlets and familial partnerships that emphasize …

Exploring The Reasons People Abuse Animals, Barbara Bittinger

Walden Dissertations and Doctoral Studies

The research on animal abuse has grown over the years which has led to studies that determine the psychological implications of animal cruelty in relation to various societal and environmental agents. From these studies, researchers have addressed animal abuse and cruelty in general but have not established the cause of the behavior or reasons why people abuse animals. The purpose of this qualitative study was to explore the reasons motivating human beings to abuse animals. Using the qualitative method, this study used snowball sampling to interview a total of 10 professionals who work in the fields of veterinary medicine (veterinarians …

The Perceived Effectiveness And Evolution Of First-Semester Nursing Students’ Studying Methods, Elizabeth Brown

Walden Dissertations and Doctoral Studies

Little research has been done to identify the study strategies used by nursing students during their first nursing classes despite studies indicating they have poor study skills, making the nursing program challenging and causing many of the students to decide to leave after their first semester. The purpose of this qualitative study was to improve the understanding of registered nursing students’ study strategies during their first semester of nursing classes. Winne and Hadwin’s self-regulated learning model was used as the conceptual framework to answer the research questions about students’ study strategies during their first semester of nursing classes, how they …

Comparing Motivation And Ambition Between Adolescent Mothers And Child-Free Women, Deirdre Lynn Jones Lowman

Walden Dissertations and Doctoral Studies

Recent studies have concluded that adolescent pregnancy and subsequent motherhood can contribute to mental health stressors, acting as potential barriers to ambition and motivation. Researchers have explored motivation and ambition; however, there is little or no research comparing motivation and ambition between adolescent mothers and child-free women. The purpose of this casual-comparative study was to compare motivation levels and ambition values between adolescent mothers, age 18-24, and women of the same age range who are child-free. Deci and Ryan's self-determination theory as the theoretical lens, and the Intrinsic Motivation Inventory and Aspirations Index, were used as data collection instruments. Recruitment …

Strategies To Increase Membership In A Canadian Nonprofit Protecting Rights And Benefits Of Retired Military Personnel, Bruce Requa

Walden Dissertations and Doctoral Studies

Nonprofit organization leaders with an advocacy mission are increasingly challenged to identify, convert, and maintain their membership base to sustain the effectiveness of their advocacy reach and effectiveness. Grounded in stakeholder theory, the purpose of this qualitative single case study was to explore strategies some nonprofit leaders used to increase membership in a Canadian nonprofit protecting the rights and benefits of retired military personnel. The participants included four leaders of a small nonprofit organization in Ontario, Canada, who have directly or indirectly implemented membership strategies. Data were collected through semistructured interviews, client organizational documents, the organization’s website, an assessment of …

Association Between Dietary Phytoestrogen Intake And Xenoestrogen Exposure And Estrogen-Dependent Cancers, Pisita Bolsue

Walden Dissertations and Doctoral Studies

The role of circulating estrogens and the impact of lifetime exposure to multiple sources of exogenous estrogens as factors in carcinogenesis were not well understood. Research showed conflicting results when dietary phytoestrogen (PE) intake and xenoestrogen (XE) exposure occurred independently and when co-exposed. The purpose of this quantitative cross-sectional study was to investigate the association between dietary PE intake and XE exposure and the development of estrogen-dependent cancers in an epidemiological context. The advanced model of the epidemiology triangle was the theoretical framework for the current study in which binary logistic regression was employed on secondary data from the 2003–2006 …

Relationship Between Childhood Trauma, ,Adverse Childhood Experiences, And Self-Management Of Type 1 And Type 2 Diabetes, Deserie J. Otoole

Walden Dissertations and Doctoral Studies

AbstractPoorly controlled diabetes is the result of lack of self-care, which contributes to complications, ill quality in life, the rise in health care costs, and early death. The purpose of this quantitative, nonexperimental study was to examine the extent to which diabetes type (Type 1 and Type 2), childhood trauma, and adverse childhood experiences predict diabetes self-management (glucose management, dietary control, physical activity, health care use, total self-management). Contemporary trauma theory suggests that early childhood trauma results in negative health-related consequences in adulthood. Standard multiple regression analyses showed that (a) higher levels of physical neglect and emotional abuse predicted poorer …

Exploring Perspectives Of African American Pentecostal Clergy Scripture Teachings Regarding Mental Illness, Phyllis Bethea Foye

Walden Dissertations and Doctoral Studies

Previous literature has noted that African American Pentecostals (AAP) avoid seeking secular care for mental health concerns. The purpose of this phenomenological qualitative study was to explore the lived experiences of AAP pastors’ beliefs and teachings associated with mental health care as well as stigmas regarding that care, using Niebuhr’s synthesis theory, Arnheim’s convergence theory, and Bronfenbrenner’s ecological system theory of human development. Sixteen AAP senior pastors were interviewed to explore four research questions regarding their beliefs about secular mental health care, Bible Scripture teachings, seeking support from clergy, and mental health education that may impact the acceptance of secular …

Adult Learning And Motivation Of Students Previously Involved In The U.S. Criminal Justice System, Saudia Krystal Mohammed

Walden Dissertations and Doctoral Studies

Motivation is an important factor in the overall success, achievement potential, and capabilities of students, especially adult learners. For individuals who are currently in the criminal justice system, motivator is a key factor in degree obtainment, research shows. However, there is limited research on adult learners who have previously been involved in the U.S. criminal justice system and the motivational factors that led to their academic reengagement. The purpose of this study was to gain a better understanding of those motivational factors. The theoretical framework that underpinned this study was the transformative learning theory, which centers on how learners make …

Strategies To Reduce Food Waste In Restaurants, Andrea L. Ratliff

Walden Dissertations and Doctoral Studies

Abstract Some restaurant business owners lack food waste strategies to maintain or increase profits. Restaurant business owners are concerned with increases in food waste leading to a loss of business profitability and may lack food waste strategies to maintain or increase profits. Grounded in stakeholder theory, the purpose of this qualitative single case study was to explore strategies restaurant business owners used to decrease food waste to maintain or increase profit. Participants in this study comprised five restaurant owners in a metropolitan suburb on the United States east coast who successfully reduced food waste in their operations to maintain or …