Digital Commons Network^™

Effect Of Intense Social Media Use On Middle School At-Risk Students Test Scores In Science And Math: An Ordinal Logistic Regression Analysis, Terry M. Johnson

Doctoral Dissertations and Projects

The purpose of this quantitative correlational study was to investigate the intensity of social networking use, gender, and socioeconomic status as possible predictors of eighth grade at-risk middle school students’ math and science test scores. Because this study hypothesized a general linear model between an ordinal response variable and more than one explanatory variables, ordinal logistic regression analysis was used. Social media is pervasive in the daily lives of students and so it can have a possible deleterious influence on student achievement. This idea continues to animate practitioners, researchers, parents, and all others interested in the achievement and success of …

Lived Experiences And Insight On Development Of Emotional Intelligence In Professional Nursing Practice, Jennifer L. Jessen

Dissertations

The purpose of this qualitative, experiential narrative study was to examine how emotional intelligence is applied in clinical nursing practice and how a nurse develops those skills in professional practice using a qualitative, experiential narrative design. The selected research participant was asked to verify her emotional quotient (EQ) score with the MSCEIT emotional intelligence test and participate in repeated interviews detailing the major events, patients, coworkers, mentors, and support systems in her life from her first experiences in healthcare to the present. Evidence of emotional intelligence (EI) was identified in her stories and applied to the Salovey and Mayer model …

Evaluation Of Two-Dimensional (2d) Versus Three-Dimensional (3d) Video Tutorials In Cataract Surgery For New Trainees, Yuxi Zheng, Saif Hamdan, Jonathan Siktberg, Jonathan Barnett, Sylvia L. Groth, Nathan Podoll, Laura Wayman, Jennifer L. Lindsey

Journal of Academic Ophthalmology

Abstract

Purpose Microscopic ophthalmic surgery requires an understanding of three-dimensional (3D) spaces within the eye. Recently, there has been an increase in 3D video training tools in health care. Studies have evaluated the efficacy of 3D tutorials in general surgery, but little has been published within ophthalmology. We present a randomized study evaluating differences in surgically naïve trainees after watching either a 2D or 3D phacoemulsification tutorial.

Design This was a double-blind, randomized study. A group of third and fourth year medical students at our institution were randomized with stratified randomization based on prior surgical courses to control for differences …

Lef1 Drives A Central Memory Program And Supports Antitumor Activity Of Natural Killer T Cells, Ho Ngai, Gabriel A Barragan, Gengwen Tian, Julien C Balzeau, Chunchao Zhang, Amy N Courtney, Linjie Guo, Xin Xu, Michael S Wood, Janice M Drabek, Thorsten Demberg, Caroline M Sands, Cynthia N Chauvin-Fleurence, Erica J Di Pierro, Jeffrey M Rosen, Leonid S Metelitsa

Faculty, Staff and Students Publications

Vα24-invariant natural killer T cells (NKT) possess innate antitumor properties that can be exploited for cancer immunotherapy. We have shown previously that the CD62L+ central memory-like subset of these cells drives the in vivo antitumor activity of NKTs, but molecular mediators of NKT central memory differentiation remain unknown. Here, we demonstrate that relative to CD62L- cells, CD62L+ NKTs express a higher level of the gene encoding the Wnt/β-catenin transcription factor lymphoid enhancer binding factor 1 (LEF1) and maintain active Wnt/β-catenin signaling. CRISPR/Cas9-mediated LEF1 knockout reduced CD62L+ frequency after antigenic stimulation, whereas Wnt/β-catenin activator Wnt3a ligand increased CD62L+ frequency. LEF1 overexpression …

Cellular Composition And Circuit Organization Of The Locus Coeruleus Of Adult Mice, Andrew Mckinney, Ming Hu, Amber Hoskins, Arian Mohammadyar, Nabeeha Naeem, Junzhan Jing, Saumil S Patel, Bhavin R Sheth, Xiaolong Jiang

Faculty, Staff and Students Publications

The locus coeruleus (LC) houses the vast majority of noradrenergic neurons in the brain and regulates many fundamental functions, including fight and flight response, attention control, and sleep/wake cycles. While efferent projections of the LC have been extensively investigated, little is known about its local circuit organization. Here, we performed large-scale multipatch recordings of noradrenergic neurons in adult mouse LC to profile their morpho-electric properties while simultaneously examining their interactions. LC noradrenergic neurons are diverse and could be classified into two major morpho-electric types. While fast excitatory synaptic transmission among LC noradrenergic neurons was not observed in our preparation, these …

Genome-Wide Screening Reveals The Genetic Basis Of Mammalian Embryonic Eye Development, Justine M Chee, Louise Lanoue, Dave Clary, Kendall Higgins, Lynette Bower, Ann Flenniken, Ruolin Guo, David J Adams, Fatima Bosch, Robert E Braun, Steve D M Brown, H-J Genie Chin, Mary E Dickinson, Chih-Wei Hsu, Michael Dobbie, Xiang Gao, Sanjeev Galande, Anne Grobler, Jason D Heaney, Yann Herault, Martin Hrabe De Angelis, Fabio Mammano, Lauryl M J Nutter, Helen Parkinson, Chuan Qin, Toshi Shiroishi, Radislav Sedlacek, J-K Seong, Ying Xu, Brian Brooks, Colin Mckerlie, K C Kent Lloyd, Henrik Westerberg, Ala Moshiri

Faculty, Staff and Students Publications

BACKGROUND: Microphthalmia, anophthalmia, and coloboma (MAC) spectrum disease encompasses a group of eye malformations which play a role in childhood visual impairment. Although the predominant cause of eye malformations is known to be heritable in nature, with 80% of cases displaying loss-of-function mutations in the ocular developmental genes OTX2 or SOX2, the genetic abnormalities underlying the remaining cases of MAC are incompletely understood. This study intended to identify the novel genes and pathways required for early eye development. Additionally, pathways involved in eye formation during embryogenesis are also incompletely understood. This study aims to identify the novel genes and pathways …

Tumor-Associated Nonmyelinating Schwann Cell-Expressed Nuclear Export Signal Mutation Of Epidermal Growth Factor Receptor Enhances Malignant Phenotypes Of Cancer Cells, Chengcao Sun, Youqiong Ye, Zhi Tan, Yuan Liu, Yajuan Li, Wei Hu, Ke Liang, Sergey D Egranov, Lisa Angela Huang, Zhao Zhang, Yaohua Zhang, Jun Yao, Tina K Nguyen, Zilong Zhao, Andrew Wu, Jeffrey R Marks, Abigail S Caudle, Aysegul A Sahin, Jianjun Gao, Seth T Gammon, David Piwnica-Worms, Jian Hu, Paul J Chiao, Dihua Yu, Mien-Chie Hung, Michael A Curran, George A Calin, Haoqiang Ying, Leng Han, Chunru Lin, Liuqing Yang

Faculty, Staff and Student Publications

One of the major obstacles to treating pancreatic ductal adenocarcinoma (PDAC) is its immunoresistant microenvironment. The functional importance and molecular mechanisms of Schwann cells in PDAC remains largely elusive. We characterized the gene signature of tumor-associated nonmyelinating Schwann cells (TASc) in PDAC and indicated that the abundance of TASc was correlated with immune suppressive tumor microenvironment and the unfavorable outcome of patients with PDAC. Depletion of pancreatic-specific TASc promoted the tumorigenesis of PDAC tumors. TASc-expressed long noncoding RNA (lncRNA) plasmacytoma variant translocation 1 (

Ssris Differentially Modulate The Effects Of Pro-Inflammatory Stimulation On Hippocampal Plasticity And Memory Via Sigma 1 Receptors And Neurosteroids, Yukitoshi Izumi, Angela M Reiersen, Eric J Lenze, Steven J Mennerick, Charles F Zorumski

2020-Current year OA Pubs

Certain selective serotonin reuptake inhibitors (SSRIs) have anti-inflammatory effects in preclinical models, and recent clinical studies suggest that fluvoxamine can prevent deterioration in patients with COVID-19, possibly through activating sigma 1 receptors (S1Rs). Here we examined potential mechanisms contributing to these effects of fluvoxamine and other SSRIs using a well-characterized model of pro-inflammatory stress in rat hippocampal slices. When hippocampal slices are exposed acutely to lipopolysaccharide (LPS), a strong pro-inflammatory stimulus, basal synaptic transmission in the CA1 region remains intact, but induction of long-term potentiation (LTP), a form of synaptic plasticity thought to contribute to learning and memory, is completely …

Vol. 42, No. 6 - Whole No. 279, Eleanor M. Farrell

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 42, No. 5 - Whole No. 278, Eleanor M. Farrell

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 42, No. 1 - Whole No. 274, Eleanor M. Farrell

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 41, No. 11 - Whole No. 272, Eleanor M. Farrell

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 41, No. 8 - Whole No. 269, Eleanor M. Farrell

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

From In-Person To Virtual: A Case Study Of An Animal-Assisted Visiting Program In A Pediatric Setting, Whitney Romine

People and Animals: The International Journal of Research and Practice

This article focuses on the practical aspects of converting a successful in-person AAA program to a virtual program in a health care setting including human, canine, and physical resources; animal welfare considerations; training, infection control, and safety guidelines; and visit delivery procedures. In 1992, an interdisciplinary team at Akron Children’s Hospital founded the Doggie Brigade, an animal-assisted activities (AAA) program where volunteer therapy dogs and their handlers visit pediatric patients. The program has become a cornerstone of the hospital’s culture over its now 30-year tenure. In March 2020, the announcement of the COVID-19 pandemic forced health care organizations to suspend …

Sample Multiplexing-Based Targeted Pathway Proteomics With Real-Time Analytics Reveals The Impact Of Genetic Variation On Protein Expression., Qing Yu, Xinyue Liu, Mark P Keller, Jose Navarrete-Perea, Tian Zhang, Sipei Fu, Laura P Vaites, Steven R Shuken, Ernst Schmid, Gregory R Keele, Jiaming Li, Edward L Huttlin, Edrees H Rashan, Judith Simcox, Gary Churchill, Devin K Schweppe, Alan D Attie, Joao A Paulo, Steven P Gygi

Faculty Research 2023

Targeted proteomics enables hypothesis-driven research by measuring the cellular expression of protein cohorts related by function, disease, or class after perturbation. Here, we present a pathway-centric approach and an assay builder resource for targeting entire pathways of up to 200 proteins selected from >10,000 expressed proteins to directly measure their abundances, exploiting sample multiplexing to increase throughput by 16-fold. The strategy, termed GoDig, requires only a single-shot LC-MS analysis, ~1 µg combined peptide material, a list of up to 200 proteins, and real-time analytics to trigger simultaneous quantification of up to 16 samples for hundreds of analytes. We apply GoDig …

No. 05: Migrant Women’S Food Insecurity Experiences In The Breadbasket Of Ghana, Jemima Nomunume Baada, Moses Kansanga, Joseph Kangmennaang, Isaac Luginaah

Migration and Food Security (MiFOOD) Network

Migration has become a safety net for smallholder farmers across Africa in response to rapidly deteriorating climatic conditions and the resulting low agricultural productivity. In semi-arid northern Ghana, especially the Upper West Region, many people migrate to rural farming communities in the Middle Belt of the country – popularly referred to as Ghana’s breadbasket – to meet their food security needs. In recent times, there has been an increase in the involvement of women in these migration patterns. This notwithstanding, many studies on migration and food security in Ghana continue to focus on the experiences of households or male migrants, …

The Indiana Statesman, February 2, 2023, Indiana State University

Student Newspaper

Parent support: Lactation room added to HMSU; Sycamores brave icy conditions in January

Issue 411: February 2-16, 2023, The Local Voice

The Local Voice

No abstract provided.

Bats Increased Foraging Activity At Experimental Prey Patches Near Hibernacula, Winifred F. Frick, Yvonne A. Dzal, Kristin A. Jonasson, Michael D. Whitby, Amanda M. Adams, Christen Long, John E. Depue, Christian M. Newman, Craig K. R. Willis, Tina L. Cheng

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

1. Emerging infectious diseases in wildlife can threaten vulnerable host populations. Actions targeting habitat improvements to aid population resilience and recovery may be beneficial long-term strategies, yet testing the efficacy of such strategies before major conservation investments are made can be challenging.

2. The disease white-nose syndrome (WNS) has caused severe declines in several species of North American hibernating bats. We tested a novel conservation approach targeted at improving foraging conditions near bat hibernacula by experimentally manipulating insect density in the pre-hibernation fattening period and spring emergence recovery period. We measured foraging (feeding buzzes) and echolocation activity of little brown bats Myotis …

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The Comment, February 2, 2023, Bridgewater State University

The Comment

No abstract provided.

Evaluation Of Gross Energy Concentration Of Neutral Detergent Fiber Contained In Feed And Fecal Samples, J. D. Stypinski, Paul J. Kononoff, W. P. Weiss

Department of Animal Science: Faculty Publications

Starch and NDF are usually assumed to contain the same concentration of gross energy (GE), but NDF is more variable in chemical composition and varies more in the extent of digestion. The variable chemical composition of NDF may have direct implications on dairy nutrition models that predict dietary GE and use this estimate for also predicting digestible energy. For example, when NDF is enriched in lignin and protein, the concentration of GE would increase, whereas NDF enriched in ash would have the opposite effect. Current nutritional models, such as the NASEM (2021) and CNCPS (6.55), assume a GE coefficient of …

Paternity Patterns In A Long-Term Resident Bottlenose Dolphin Community, Debbie Duffield, Randall Wells

Biology Faculty Publications and Presentations

Genetic analyses, initiated in 1984, have played a major role in our understanding of the structure and social relationships of the long-term resident community of common bottlenose dolphins (Tursiops truncatus) in Sarasota Bay, Florida (SBDC). One component of our ongoing study of the community’s social system involves using blood samples from periodic catch-and-release sampling for life history and health assessment studies, as well as skin from biopsy dart sampling studies and strandings, to investigate paternity and mating strategies in this community. These analyses, covering a span of four generations of calves, were originally based on chromosomes and protein electrophoresis, but …

The Ongoing Patent Battle Over Crispr/Cas-9, Shifra Ben-Jacob

Cardozo Journal of Conflict Resolution (CJCR) Blog

CRISPR/Cas 9 is a bacterial defense system for editing genomes that has been coined one of the most monumental biotechnologies since the discovery of the polymerase chain reaction (PCR). Since 2012, two research teams, one out of the University of California, Berkeley, and the other from both the Broad Institute and the Massachusetts Institute of Technology, have been battling an ongoing patent war. The US Patent and Trademark Office (USPTO) is left to decide who can claim the technology as their own.

This post was originally published on the Cardozo Journal of Conflict Resolution website on February 2, 2023. The …

Conformity And Tradition Are More Important Than Environmental Values In Constraining Resource Overharvest, Glenn Wright, Carl Salk, Piotr Magnuszewski, Joanna Stefanska, Krister Anderson, Jean Paul Benavides, Robin Chazdon

Faculty, Staff, and Students

We present the results of a hybrid research design that borrows from both experimental techniques—experimental games—and observational techniques—surveys—to examine the relationships between basic human values and exposure to natural ecosystems, on the one hand, and collective action for resource governance, on the other. We initially hypothesize that more frequent exposure to forests, and more pro-environmental values will be associated with more conservation action. However, we find that other values—tradition and conformity—are more important than pro-environmental values or exposure to nature. Our results imply that resource governance is likely to be more successful where resource users hold values that facilitate cooperation, …

Systems Thinking Activities Used In K-12 For Up To Two Decades, Diana Fisher, Systems Thinking Association

Complex Systems Faculty Publications and Presentations

Infusing systems thinking activities in pre-college education (grades K-12) means updating precollege education so it includes a study of many systemic behavior patterns that are ubiquitous in the real world. Systems thinking tools include those using both paper and pencil and the computer and enhance learning in the classroom making it more student-centered, more active, and allowing students to analyze problems that have been heretofore beyond the scope of K-12 classrooms. Students in primary school have used behavior over time graphs to demonstrate dynamics described in story books, like the Lorax, and created stock-flow diagrams to describe what was needed …

Clemson Board Of Trustee Minutes, Full Board Minutes, 2023 Februrary 2, Clemson University Board Of Trustees

Minutes

No abstract provided.

Clemson Board Of Trustee Minutes, Finance And Facilities Committee, 2023 Februrary 2, Clemson University Board Of Trustees

Minutes

No abstract provided.

Regional Anesthesia Simulation: The Use Of Pork For Nerve Block Models, David Rosales, Amy Snow

Group: Samford University Moffett & Sanders School of Nursing

The utilization of ultrasound-guided regional anesthesia (UGRA) has become a safe and effective means of providing perioperative pain management. Regional anesthesia is a desirable component of the multimodal approach to postoperative pain control, minimizing opioid consumption, recovery time, and inpatient hospital stay. One example of UGRA is the pectoral nerve (PECS) block for breast surgery pain control. Simulation-based regional anesthesia education can help develop student registered nurse anesthetists' knowledge, skills, and confidence, bridging the gap between initial training and clinical practice. Do injectable nerve block models, compared to other teaching simulation prototypes, influence students' nerve block performance in the clinical …

Interactions Between Humans And Dogs During The Covid-19 Pandemic: Recent Updates And Future Perspectives, Mohamed S. Kamel, Amr A. El-Sayed, Rachel A. Munds, Mohit S. Verma

Purdue University Libraries Open Access Publishing Fund

COVID-19 is one of the deadliest epidemics. This pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but the role of dogs in spreading the disease in human society is poorly understood. This review sheds light on the limited susceptibility of dogs to COVID-19 infections which is likely attributed to the relatively low levels of angiotensin-converting enzyme 2 (ACE2) in the respiratory tract and the phylogenetic distance of ACE2 in dogs from the human ACE2 receptor. The low levels of ACE2 affect the binding affinity between spike and ACE2 proteins resulting in it being uncommon for dogs to …

Intraguild Predation Is Increased In Areas Of Low Prey Diversity In A Generalist Predator Community, Stella F. Uiterwaal, Amber J. Squires, Bennett A. Grappone, Brian Dillard, Ariadne Castaneda, Sora L. Kim, John P. Delong

School of Biological Sciences: Faculty Publications

1. Niche differentiation and intraguild predation (IGP) can allow ecologically similar species to coexist, although it is unclear which coexistence mechanism predominates in consumer communities. Until now, a limited ability to quantify diets from metabarcoding data has precluded the use of sequencing data to determine the relative importance of these mechanisms.

2. Here, we pair a recent metabarcoding quantification approach with stable isotope analysis to examine diet composition in a wolf spider community.

3. We compare the prevalence of resource partitioning and IGP in these spiders and test whether factors that influence foraging performance, including individual identity, morphology, prey community and environmental conditions, …

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