Digital Commons Network^™

Indigenous Science Network Bulletin - March 2023

Indigenous Science Network

The first issue of indigenous Science Network Bulletin for 2023 welcomes Yolanda Lopez-Maldonado and Torres Webb to the First Nations editorial board. The editorial features Yolanda Lopez Maldonado, an environmental scientist of Maya ancestry, and the Bulletin contains news and views, resources; papers; and information about Indigenous Astronomy and conferences and seminars.

Connecting Higher Education To Workplace Activities And Earnings, Hung Chau, Sarah H. Bana, Baptiste Bouvier, Morgan R. Frank

Economics Faculty Articles and Research

Higher education is a source of skill acquisition for many middle- and high-skilled jobs. But what specific skills do universities impart on students to prepare them for desirable careers? In this study, we analyze a large novel corpora of over one million syllabi from over eight hundred bachelors’ granting US educational institutions to connect material taught in higher education to the detailed work activities in the US economy as reported by the US Department of Labor. First, we show how differences in taught skills both within and between college majors correspond to earnings differences of recent graduates. Further, we use …

Extroversion - Introversion Traits And Their Influence On The Humanistic Culture In Edward Albee’S The Zoo Story, Inam Hashim Hadi

Alustath Journal for Human and Social Sciences

The social, political, and cultural scene of post-world war II America witnessed considerable changes where lack of communication, meaninglessness, solitude, class distinction, and other related issues prevailed, stripping man of his humanity. In the mid-twentieth century, dramatists including Edward Albee, among other writers, tried to revive a new vitalized social ideology to transform the current mode of human's thought whose effect exceeded the limits leading man to segregate himself from others. Albee was resentful of the cultural orientation during his time and he criticized the contemporary social standards in his attempt to sublimate human's life experiences partly as a self-healing …

Elevating The Silicon Slopes, Joseph Evans

Undergraduate Honors Theses

From Utah’s humble beginnings in agriculture and mining, Utah has become an economic powerhouse in the United States, largely due to the rise of Silicon Slopes. Despite the successes of Silicon Slopes, there are still significant shortcomings related to diversity and inclusion in Silicon Slopes that must be remediated if it intends to achieve its economic aspirations and ensure its economic benefits flow to people of all types and backgrounds. This work outlines both the rise of Silicon Slopes as well as existing and potential private- and state-ordered solutions that may be implemented to overcome Silicon Slopes’ existing diversity and …

Spectrum, Volume 50, Issue 6, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: The Use of Al in Education -- Train Derailment in Ohio -- Roald Dahl Rewritten -- New Degree to Pursue: School Counseling -- Tired of Dining Hall Food? -- The Pogues Journey Continues -- “Mom, I Don’t Want-War” -- New Era For SHU Baseball -- Women’s Wrestling Competes at Nationals -- A Fellow Pioneer in Need

Diurnal Time-Activity Budget And Habitat Use Of Whooping Cranes (Grus Americana) In The Reintroduced Louisiana Nonmigratory Population, Phillip L. Vasseur, Sammy L. King, Michael D. Kaller

Faculty Publications

Time-activity budget studies provide valuable insights for better understanding animal behavior relative to spatial and temporal habitat use. We examined a reintroduced, nonmigratory Whooping Crane (Grus americana) population to determine how time-activity budgets change relative to crane age, sex, habitat type, and season. Our study area encompassed natural marshes and working wetlands primarily in southwestern Louisiana. From June 2012 to January 2016, we conducted continuous focal sampling on individuals (n = 27) from the first 4 captive-reared cohorts released in the state. We classified age groups as juveniles, subadults, and adults, and identified 5 main habitat types utilized by cranes …

Remote Medical Diagnosis Via Infrared Thermography And Augmented Reality, Frederick M. Selkey

USF Tampa Graduate Theses and Dissertations

Fast, accurate, and non-invasive diagnostic techniques are required by the medical industry to increase the success of medical treatments and enhance the quality of patient care. Medical IRT has been demonstrated reasonably effective at diagnosing and monitoring several physiological conditions. Diversities in the human body, physical and psychological condition, measurement equipment, and environment all influence the sensitive readings obtained by passive IR measurement devices. New standards for medical IRT and fever screening have been demonstrated effective, but there is limited adherence to the guidelines [36]. Absolute temperature readings require regular calibration checks and can easily be thrown off by noise. …

Student Senate Meeting Minutes March 15, 2023, Student Senate-Winona State University

Student Senate Meeting Minutes

This document is the official Winona State University Student Senate Minutes March 15, 2023.

Bright Yellow, Donna Emerson

Westview

No abstract provided.

Meeting Lisa, Norbert Kovacs

Westview

No abstract provided.

Westview: Vol. 37, Iss. 1 (Spring 2023), Westview Staff

Westview

No abstract provided.

Evaluation Of A Story-Telling Approach To Educate Minority Populations About Inherited Cancer, Celestyn B. Angot

USF Tampa Graduate Theses and Dissertations

Utilization of hereditary cancer genetic counseling and testing services is substantially lower among minority populations compared to white populations due, in part, to lower levels of awareness and knowledge. To help improve awareness, we designed a 7-minute video that uses storytelling to translate knowledge of genetic testing and hereditary cancer to individuals who have a personal history or family history of cancer. Consented participants were asked baseline questions about hereditary cancer and genetic testing, reviewed the video, and provided feedback on its content, understandability, and visual appeal during semi-structured interviews. Data were coded and analyzed to identify themes and determine …

Spontaneous Activity Patterns In Human Attention Networks Code For Hand Movements, Lu Zhang, Lorenzo Pini, Dohyun Kim, Gordon L Shulman, Maurizio Corbetta

2020-Current year OA Pubs

Recent evidence suggests that, in the absence of any task, spontaneous brain activity patterns and connectivity in the visual and motor cortex code for natural stimuli and actions, respectively. These "resting-state" activity patterns may underlie the maintenance and consolidation (replay) of information states coding for ecological stimuli and behaviors. In this study, we examine whether replay patterns occur in resting-state activity in association cortex grouped into high-order cognitive networks not directly processing sensory inputs or motor outputs. Fifteen participants (7 females) performed four hand movements during an fMRI study. Three movements were ecological. The fourth movement as control was less …

Generation Of Periventricular Reactive Astrocytes Overexpressing Aquaporin 4 Is Stimulated By Mesenchymal Stem Cell Therapy, María García-Bonilla, Kirill Shumilov, James P Mcallister 2nd, David D Limbrick Jr., Et Al.

2020-Current year OA Pubs

Aquaporin-4 (AQP4) plays a crucial role in brain water circulation and is considered a therapeutic target in hydrocephalus. Congenital hydrocephalus is associated with a reaction of astrocytes in the periventricular white matter both in experimental models and human cases. A previous report showed that bone marrow-derived mesenchymal stem cells (BM-MSCs) transplanted into the lateral ventricles of hyh mice exhibiting severe congenital hydrocephalus are attracted by the periventricular astrocyte reaction, and the cerebral tissue displays recovery. The present investigation aimed to test the effect of BM-MSC treatment on astrocyte reaction formation. BM-MSCs were injected into the lateral ventricles of four-day-old hyh …

Kdm6a Loss Triggers An Epigenetic Switch That Disrupts Urothelial Differentiation And Drives Cell Proliferation In Bladder Cancer, Hong Qiu, Jennifer K Bolzenius, Angela Halstead, Vivek Arora, Et Al.

2020-Current year OA Pubs

UNLABELLED: Disruption of KDM6A, a histone lysine demethylase, is one of the most common somatic alternations in bladder cancer. Insights into how KDM6A mutations affect the epigenetic landscape to promote carcinogenesis could help reveal potential new treatment approaches. Here, we demonstrated that KDM6A loss triggers an epigenetic switch that disrupts urothelial differentiation and induces a neoplastic state characterized by increased cell proliferation. In bladder cancer cells with intact KDM6A, FOXA1 interacted with KDM6A to activate genes instructing urothelial differentiation. KDM6A-deficient cells displayed simultaneous loss of FOXA1 target binding and genome-wide redistribution of the bZIP transcription factor ATF3, which in turn …

Nationwide Results Of Microorganism Antigen Testing As A Component Of Preoperative Synovial Fluid Analysis., Krista O'Shaughnessey Toler, Pearl Ravindra Paranjape, Alex Mclaren, Brett Levine, Alvin Ong, Carl Deirmengian

Rothman Institute Papers

BACKGROUND: Antigen immunoassays to detect synovial fluid (SF) microorganisms have recently been made available for clinical use. The purpose of this study was to determine the sensitivity and specificity of an SF microorganism antigen immunoassay detection (MID) panel, evaluate the panel's capability to detect microorganisms in the setting of culture-negative periprosthetic joint infection (PJI), and determine diagnostic predictive values of the MID panel for PJI.

METHODS: This study included 67,441 SF samples obtained from a hip or knee arthroplasty, from 2,365 institutions across the United States, submitted to 1 laboratory for diagnostic testing. All data were prospectively compiled and then …

Nebraska Farmland Values And Cash Rental Rates In 2023, Jim Jansen, Jeffrey Stokes

Cornhusker Economics

The market value of agricultural land in Nebraska increased by 14% over the prior year to an average of US $3,835 per acre, according to the 2023 Nebraska Farm Real Estate Market Survey. This marks the second-largest increase in the market value of agricultural land in Nebraska since 2014 and the highest non-inflation-adjusted state-wide land value in the 45-year history of the survey.

The University of Nebraska-Lincoln’s Department of Agricultural Economics annually surveys land industry professionals across Nebraska, including appraisers, farm and ranch managers, agricultural bankers, and related industry professionals. Results from the survey are divided by land class and …

Love Hertz: Corporate Groups And Insolvency Forum Selection, John A. E. Pottow

Law & Economics Working Papers

The Hertz bankruptcy got a lot of attention, including for its bizarre equity trading. A less heralded but more significant legal aspect of that insolvency, however, was its complex interaction of cross-border insolvency proceedings.

This article discusses the “centripetal” and “centrifugal” forces in the Hertz case that counselled a U.S.-based centralized solution for an international enterprise comprising over 10,000 branches centripetally but also accommodated centrifugal European resistance to subject directors to the consequences of filing their entities in a foreign jurisdiction. This not uncommon constellation of incentives required not a COMI shift but what this article terms a jurisdiction shift …

Repertoire For A Graduate Tenor Trombone Audition, An Annotated List Of Trombone Solos For A Master's Program Audition, Ashley Rands

Undergraduate Honors Theses

Students in the field of trombone performance may find preparation difficult for graduate auditions due to the diversity of required selections and lack of standard repertoire. While not always explicitly available, many graduate programs have a list of required or recommended solos. This brief study is the result of preparations for graduate school auditions, including the challenge of deciding what solos to perform. After looking at application requirements for fifteen strong trombone programs, I created a list of the most frequently required/recommended solos. The study of the pieces provided insight into specific difficulties and performance notes for each solo. Included …

The Role Of Nod-Like Receptors In Innate Immunity, Cassio Luiz Coutinho Almeida-Da-Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

The innate immune system in vertebrates and invertebrates relies on conserved receptors and ligands, and pathways that can rapidly initiate the host response against microbial infection and other sources of stress and danger. Research into the family of NOD-like receptors (NLRs) has blossomed over the past two decades, with much being learned about the ligands and conditions that stimulate the NLRs and the outcomes of NLR activation in cells and animals. The NLRs play key roles in diverse functions, ranging from transcription of MHC molecules to initiation of inflammation. Some NLRs are activated directly by their ligands, while other ligands …

Chronic Administration Of Melatonin: Physiological And Clinical Considerations, Donald Givler, Amy Givler, Patrick M. Luther, Danielle M. Wenger, Shahab Ahmadzadeh, Sahar Shekoohi, Amber N. Edinoff, Bradley K. Dorius, Carlo Jean Baptiste, Elyse M. Cornett, Adam M. Kaye, Alan D. Kaye

Pacific Faculty Work

Background: Exogenous melatonin is commonly used to treat insomnia, other sleep problems, and numerous medical illnesses, including Alzheimer’s disease, autism spectrum disorder, and mild cognitive impairment in adults and children. There is evolving information regarding issues with the use of chronic melatonin. Methods: The present investigation was a narrative review. Results: Melatonin usage has risen dramatically in recent years. Many countries only allow melatonin prescriptions. In the United States (U.S.), it is classified as a dietary supplement accessible over the counter and can be derived from animals, microorganisms, or, most commonly, made synthetically. No regulatory agency oversees its manufacturing or …

Fresh Produce As A Potential Vector And Reservoir For Human Bacterial Pathogens: Revealing The Ambiguity Of Interaction And Transmission, Ahmed Esmael, Rashad R. Al-Hindi, Raed S. Albiheyri, Mona G. Alharbi, Amani A. R. Filimban, Mazen S. Alseghayer, Abdulaziz M. Almaneea, Meshari Ahmed Alhadlaq, Jumaa Ayubu, Addisu D. Teklemariam

Nebraska Center for Virology: Faculty Publications

The consumer demand for fresh produce (vegetables and fruits) has considerably increased since the 1980s for more nutritious foods and healthier life practices, particularly in developed countries. Currently, several foodborne outbreaks have been linked to fresh produce. The global rise in fresh produce associated with human infections may be due to the use of wastewater or any contaminated water for the cultivation of fruits and vegetables, the firm attachment of the foodborne pathogens on the plant surface, and the internalization of these agents deep inside the tissue of the plant, poor disinfection practices and human consumption of raw fresh produce. …

The Pathogenesis Of Covid-19: Hypercoagulation And D-Dimer In Thrombotic Complications, Leonid Dubey, Halyna Lytvyn, Olha Dorosh, Nataliya Dubey, Olena Kozlova, Michal Pruc, Nina Kubikowska, Lukasz Szarpak, Kavita Batra, Francesco Chirico, Gabriella Nucera, Svitlana Doan, Uljana Shevtsiv

School of Medicine Faculty Research

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) caused a new coronavirus disease (COVID-19), which is highly contagious and its pathogenesis has not been fully elucidated. In COVID-19, the inflammation and blood coagulation systems are excessively activated. SARS-CoV- 2 damages endothelial cells and pneumocytes, which leads to disruption of hemostasis in SARS. Thromboembolism is the main cause of mortality in patients with COVID-19. Clots, including pulmonary embolism (PE) and deep vein thrombosis (DVT), ranging from minor to fatal complications of the SARS-CoV-2 infection are known. Individuals with pre-existing diseases are more susceptible to the development of blood clots and poor outcomes. …

Ecohydrology, Cultural Perceptions, And Recovery Of Freshwater Wetlands In A Heavily Managed Urban Aquifer, Jessica Ashley Balerna

USF Tampa Graduate Theses and Dissertations

Freshwater wetlands provide essential ecosystem services that influence, and are influenced by, human perceptions and behaviors. I explore these feedbacks in the Tampa Bay region, which hosts numerous freshwater wetlands subjected to population increases, economic growth, and shifting management policies. These wetlands are embedded in urban and residential areas, where people can observe and respond to changes in wetland condition over time. I utilized long-term (1991–2018), high sample size (n=152) datasets to assess how wetland inundation responds to the interactive effects of climate variation and shifts in water conservation policies primarily related to cutbacks in groundwater extraction. As wetland ecosystem …

"Emerging And Submerging": Silence, Commemoration, And Sexual Violence In Minneapolis, Alissa Roy

USF Tampa Graduate Theses and Dissertations

Dedicated in Minneapolis in October 2020, the Survivors Memorial became the first permanent memorial to survivors of sexual violence in the United States. However, as my research reveals, sexual violence has long been a part of the commemorative landscape in northeast Minneapolis. Whereas the Survivors Memorial explicitly commemorates survivors of sexual violence, a much older site, the 1936 Pioneers Monument - commemorates sexual violence through silence. This thesis argues that with the building and dedication of the Survivors Memorial, a different memory than the one embodied within the Pioneers Monument begins to take shape. An older narrative of peaceful conquest …

Connectivity And Racial Equity In Responding To Covid-19 Impacts In The Chicago Regional Food System, Rowan Obach, Tania Schusler, Paulina Vaca, Sydney Durkin, Ma'raj Sheikh

School of Environmental Sustainability: Faculty Publications and Other Works

The COVID-19 outbreak led to major disruptions in food systems across the globe. In the United States’ Chicago region, the outbreak created immediate concerns around increased hunger, food insecurity, supply chain disruptions, and loss of local livelihoods. This was especially evident in communities of color, which faced disproportionate impacts from the pandemic. In March 2020, the Chicago Food Policy Action Council (CFPAC) coordinated a Rapid Response Effort that convened people in working groups related to emergency food assistance, local food producers, small businesses, and food system workers to address urgent needs that arose due to the pandemic. Each working group …

The Alpha7 Integrin Subunit In Astrocytes Promotes Endothelial Blood-Brain Barrier Integrity, Zhihua Chen, Jack R Kelly, John E Morales, Raymond C Sun, Arpan De, Dean J Burkin, Joseph H Mccarty

Faculty, Staff and Student Publications

The blood-brain barrier (BBB) is a vascular endothelial cell boundary that partitions the circulation from the central nervous system to promote normal brain health. We have a limited understanding of how the BBB is formed during development and maintained in adulthood. We used quantitative transcriptional profiling to investigate whether specific adhesion molecules are involved in BBB functions, with an emphasis on understanding how astrocytes interact with endothelial cells. Our results reveal a striking enrichment of multiple genes encoding laminin subunits as well as the laminin receptor gene Itga7, which encodes the alpha7 integrin subunit, in astrocytes. Genetic ablation of Itga7 …

Sequential Targeting Of Retinoblastoma And Dna Synthesis Pathways Is A Therapeutic Strategy For Sarcomas That Can Be Monitored In Real Time, Tuyen Duong Thanh Nguyen, Yan Wang, Tuyen N Bui, Rossana Lazcano, Davis R Ingram, Min Yi, Varshini Vakulabharanam, Linjie Luo, Marc A Pina, Cansu Karakas, Mi Li, Nicole M Kettner, Neeta Somaiah, Peter J Hougton, Osama Mawlawi, Alexander J Lazar, Kelly K Hunt, Khandan Keyomarsi

Faculty, Staff and Student Publications

Treatment strategies with a strong scientific rationale based on specific biomarkers are needed to improve outcomes in patients with advanced sarcomas. Suppression of cell cycle progression through reactivation of the tumor suppressor retinoblastoma (Rb) using CDK4/6 inhibitors is a potential avenue for novel targeted therapies in sarcomas that harbor intact Rb signaling. Here, we evaluated combination treatment strategies (sequential and concomitant) with the CDK4/6 inhibitor abemacicib to identify optimal combination strategies. Expression of Rb was examined in 1043 sarcoma tumor specimens, and 50% were found to be Rb-positive. Using in vitro and in vivo models, an effective 2-step sequential combination …

Kdm6a Loss Triggers An Epigenetic Switch That Disrupts Urothelial Differentiation And Drives Cell Proliferation In Bladder Cancer, Hong Qiu, Vladimir Makarov, Jennifer K Bolzenius, Angela Halstead, Yvonne Parker, Allen Wang, Gopakumar V Iyer, Hannah Wise, Daniel Kim, Varna Thayaparan, Daniel J Lindner, Georges-Pascal Haber, Angela H Ting, Bing Ren, Timothy A Chan, Vivek Arora, David B Solit, Byron H Lee

Faculty, Staff and Student Publications

Disruption of KDM6A, a histone lysine demethylase, is one of the most common somatic alternations in bladder cancer. Insights into how KDM6A mutations affect the epigenetic landscape to promote carcinogenesis could help reveal potential new treatment approaches. Here, we demonstrated that KDM6A loss triggers an epigenetic switch that disrupts urothelial differentiation and induces a neoplastic state characterized by increased cell proliferation. In bladder cancer cells with intact KDM6A, FOXA1 interacted with KDM6A to activate genes instructing urothelial differentiation. KDM6A-deficient cells displayed simultaneous loss of FOXA1 target binding and genome-wide redistribution of the bZIP transcription factor ATF3, which in turn repressed …

Sequential Targeting Of Retinoblastoma And Dna Synthesis Pathways Is A Therapeutic Strategy For Sarcomas That Can Be Monitored In Real Time, Tuyen Duong Thanh Nguyen, Yan Wang, Tuyen N Bui, Rossana Lazcano, Davis R Ingram, Min Yi, Varshini Vakulabharanam, Linjie Luo, Marc A Pina, Cansu Karakas, Mi Li, Nicole M Kettner, Neeta Somaiah, Peter J Hougton, Osama Mawlawi, Alexander J Lazar, Kelly K Hunt, Khandan Keyomarsi

Faculty, Staff and Student Publications

Treatment strategies with a strong scientific rationale based on specific biomarkers are needed to improve outcomes in patients with advanced sarcomas. Suppression of cell-cycle progression through reactivation of the tumor suppressor retinoblastoma (Rb) using CDK4/6 inhibitors is a potential avenue for novel targeted therapies in sarcomas that harbor intact Rb signaling. Here, we evaluated combination treatment strategies (sequential and concomitant) with the CDK4/6 inhibitor abemacicib to identify optimal combination strategies. Expression of Rb was examined in 1,043 sarcoma tumor specimens, and 50% were found to be Rb-positive. Using in vitro and in vivo models, an effective two-step sequential combination strategy …