Digital Commons Network^™

Cross-Modal Functional Connectivity Supports Speech Understanding In Cochlear Implant Users, Amanda M Fullerton, Deborah A Vickers, Robert Luke, Addison N Billing, David Mcalpine, Heivet Hernandez-Perez, Jonathan E Peelle, Jessica J M Monaghan, Catherine M Mcmahon

2020-Current year OA Pubs

Sensory deprivation can lead to cross-modal cortical changes, whereby sensory brain regions deprived of input may be recruited to perform atypical function. Enhanced cross-modal responses to visual stimuli observed in auditory cortex of postlingually deaf cochlear implant (CI) users are hypothesized to reflect increased activation of cortical language regions, but it is unclear if this cross-modal activity is "adaptive" or "mal-adaptive" for speech understanding. To determine if increased activation of language regions is correlated with better speech understanding in CI users, we assessed task-related activation and functional connectivity of auditory and visual cortices to auditory and visual speech and non-speech …

Systematic Assessment Of The Quality And Comprehensibility Of Youtube Content On Ulnar Collateral Ligament Injury And Management, Sohil S. Desai, Matthew J. Anderson, Connor R. Crutchfield, Anastasia Gazgalis, Frank J. Alexander, Charles A. Popkin, Christopher S. Ahmad

Department of Orthopaedic Surgery Faculty Papers

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A Comparison Of Perceptions Of Incivility Among Nursing Students And Faculty In Pre-Licensure Nursing Programs, Karen Aul

Dissertations

This study used a mixed method approach to examine the frequency and types of perceived and experienced uncivil behaviors among nursing students and faculty. The Incivility in Nursing (INE) Survey that was developed by Clark in 2004 was administered to a convenience sample of nursing students and faculty from four nursing programs. The sample included 159 senior pre-licensure nursing students and 14 faculty members within diploma, associate, and baccalaureate nursing education programs. Stress was mentioned in all program types as a contributing factor to student and faculty incivility. The analysis of the quantitative data found variability between nursing program types …

Visualizing The Recovery Of Patients In Critical Care Units, L Stuart, C Haynes, K Tantam, R Gardner, Ma Palomino

School of Engineering, Computing and Mathematics

This paper presents a detailed case study of the application of techniques from Information Visualization to data collected in Critical Care Units (CCUs). This data is heterogeneous and sometimes incomplete due to the pressures on staff in the environment. Thus, it can be difficult to use conventional means to visualize it meaningfully. The paper presents the software tool called CCViews. It was developed to support visualization of CCU data. It enables clinicians to view the trajectory of patient recovery and track the effectiveness of different interventions such as physiotherapy. Note that this work is underpinned by the world-famous information seeking …

Circulating Plasma Exosomal Proteins Of Either Shiv-Infected Rhesus Macaque Or Hiv-Infected Patient Indicates A Link To Neuropathogenesis, Partha K. Chandra, Stephen E. Braun, Sudipa Maity, Jorge A. Castorena-Gonzalez, Hogyoung Kim, Jeffrey G. Shaffer, Sinisa Cikic, Ibolya Rutkai, Jia Fan, Jessie J. Guidry, David K. Worthylake, Chenzhong Li, Asim B. Abdel-Mageed, David W. Busija

School of Medicine Faculty Publications

Despite the suppression of human immunodeficiency virus (HIV) replication by combined antiretroviral therapy (cART), 50–60% of HIV-infected patients suffer from HIV-associated neurocognitive disorders (HAND). Studies are uncovering the role of extracellular vesicles (EVs), especially exosomes, in the central nervous system (CNS) due to HIV infection. We investigated links among circulating plasma exosomal (crExo) proteins and neuropathogenesis in simian/human immunodeficiency virus (SHIV)-infected rhesus macaques (RM) and HIV-infected and cART treated patients (Patient-Exo). Isolated EVs from SHIV-infected (SHIV-Exo) and uninfected (CTL-Exo) RM were predominantly exosomes (particle size < 150 nm). Proteomic analysis quantified 5654 proteins, of which 236 proteins (~4%) were significantly, differentially expressed (DE) between SHIV-/CTL-Exo. Interestingly, different CNS cell specific markers were abundantly expressed in crExo. Proteins involved in latent viral reactivation, neuroinflammation, neuropathology-associated interactive as well as signaling molecules were expressed at significantly higher levels in SHIV-Exo than CTL-Exo. However, proteins involved in mitochondrial biogenesis, ATP production, autophagy, endocytosis, exocytosis, and cytoskeleton organization were significantly less expressed in SHIV-Exo than CTL-Exo. Interestingly, proteins involved in oxidative stress, mitochondrial biogenesis, ATP production, and autophagy were significantly downregulated in primary human brain microvascular endothelial cells exposed with HIV+/cART+ Patient-Exo. We showed that Patient-Exo significantly increased blood–brain barrier permeability, possibly due to loss of platelet endothelial cell adhesion molecule-1 protein and actin cytoskeleton structure. Our novel findings suggest that circulating exosomal proteins expressed CNS cell markers—possibly associated with viral reactivation and neuropathogenesis—that may elucidate the etiology of HAND.

The Link March 21, 2023, Access To Justice Institute

The Link Newsletter

No abstract provided.

Unmarked: Intellectual Property And Geography, Lorie Graham, Stephen Mcjohn

Minnesota Journal of Law, Science & Technology

No abstract provided.

Pcl And Dmso2 Composites For Bio-Scaffold Materials, Jae-Won Jang, Kyung-Eun Min, Cheolhee Kim, Chien Wern, Sung Yi

Mechanical and Materials Engineering Faculty Publications and Presentations

Polycaprolactone (PCL) has been one of the most popular biomaterials in tissue engineering due to its relatively low melting temperature, excellent thermal stability, and cost-effectiveness. However, its low cell attraction, low elastic modulus, and long-term degradation time have limited its application in a wide range of scaffold studies. Dimethyl sulfone (DMSO2) is a stable and non-hazardous organosulfur compound with low viscosity and high surface tension. PCL and DMSO2 composites may overcome the limitations of PCL as a biomaterial and tailor the properties of biocomposites. In this study, PCL and DMSO2 composites were investigated as a new bio-scaffold material to increase …

Early Agricultural Lives: Bioarchaeological Inferences From Neolithic And Early Copper Age Tombs In The Central Po Valley, Italy, Christopher J. Eck Jr.

USF Tampa Graduate Theses and Dissertations

The current project seeks to illuminate the diets of the earliest farming societies in central Northern Italy. Neolithic peoples who first began settling in the Central Po Valley sometime at the end of the seventh and beginning of the sixth millennium BCE forever changed the landscape from one of expanding sub-continental forests to one of intensive agricultural production and anthropogenic influence. A total of 109 individual burials from 24 separate infrastructure project excavations of 17 sites surrounding the modern city of Mantua, Italy were analyzed utilizing a biochemical approach and a bioarchaeological explanatory theoretical framework based within embodiment and life …

Development And Implementation Of Telemetry Devices To Identify And Characterize Sources Of Intraocular Pressure Variability In Rats, Christina M. Nicou

USF Tampa Graduate Theses and Dissertations

Eye health depends partially on intraocular pressure (IOP) as abnormal levels can lead to ocular tissue damage. Glaucoma is a neurodegenerative disease that affects nearly 80 million people worldwide [1]. It is associated with elevated IOP, which can lead to irreversible blindness. Relatively little is known about IOP dynamics and the physiological factors that affect it as IOP is typically monitored using tonometry. Tonometry is a common tool used by clinicians and researchers to measure IOP noninvasively. It provides a good estimate of IOP mean but not variance because data collection takes time. Readings can also be influenced by subject …

Spartan Daily, March 21, 2023, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2023

Volume 160, Issue 23

Acupuncture Treatment For Post-Stroke Depression: Intestinal Microbiota And Its Role, Hailun Jiang, Shizhe Deng, Jieying Zhang, Junjie Chen, Boxuan Li, Weiming Zhu, Menglong Zhang, Chao Zhang, Zhihong Meng

Faculty, Staff and Student Publications

Stroke-induced depression is a common complication and an important risk factor for disability. Besides psychiatric symptoms, depressed patients may also exhibit a variety of gastrointestinal symptoms, and even take gastrointestinal symptoms as the primary reason for medical treatment. It is well documented that stress may disrupt the balance of the gut microbiome in patients suffering from post-stroke depression (PSD), and that disruption of the gut microbiome is closely related to the severity of the condition in depressed patients. Therefore, maintaining the balance of intestinal microbiota can be the focus of research on the mechanism of acupuncture in the treatment of …

Effect Of Residential Environment As An Environmental Factor On Human Subfertility In Babylon City, Zinah Hammad, Zinah Hammad

Muthanna Medical Journal

The reproductive function has been demonstrated to be touchy to changes in the physical, psychosocial and substance conditions. The potential reproductive hazards of exposure to environmental contaminants, there had evidence for adverse reproductive effects of the physical and psychosocial environments. The aim of this study to determine the links between regional differences as an environmental factor effect on reproductive fertility in Babylon province. The present study involved 121 sub-fertile couples shows that about 43.8 % was lived in a rural area while 56.2% was lived in an urban area. Most of them with primary infertility 64(64%). About the distribution of …

The Minderoo-Monaco Commission On Plastics And Human Health, Philip J. Landrigan, Hervé Raps, Maureen Cropper, Caroline Bald, Manuel Brunner, Elvia Maya Canonizado, Dominic Charles, Thomas C. Chiles, Mary J. Donohue, Judith Enck, Patrick Fenichel, Lora E. Fleming, Christine Ferrier-Pages, Richard Fordham, Aleksandra Gozt, Carly Griffin, Mark E. Hahn, Budi Haryanto, Richard Hixson, Hannah Ianelli, Bryan D. James, Pushpam Kumar, Amalia Laborde, Kara Lavender Law, Keith Martin, Jenna Mu, Yannick Mulders, Adetoun Mustapha, Jia Niu, Sabine Pahl

School of Biological and Marine Sciences

Background: Plastics have conveyed great benefits to humanity and made possible some of the most significant advances of modern civilization in fields as diverse as medicine, electronics, aerospace, construction, food packaging, and sports. It is now clear, however, that plastics are also responsible for significant harms to human health, the economy, and the earth's environment. These harms occur at every stage of the plastic life cycle, from extraction of the coal, oil, and gas that are its main feedstocks through to ultimate disposal into the environment. The extent of these harms not been systematically assessed, their magnitude not fully quantified, …

Pasture Pig Basics, Jacob Hadfield, Jessie Hadfield, Joshua Dallin, Lorie Millward

All Current Publications

With an increasing push for more sustainable agriculture practices, raising pigs on pasture has gained much attention over recent years. Although it is possible to raise pigs on pasture, and this production method may support some sustainability goals, there are some important considerations. This fact sheet provides insight and answers to aspiring pig farmers so that they can make better-informed decisions before purchasing their pigs.

Exercise Training To Improve Brain Health In Older People Living With Hiv: Study Protocol For A Randomized Controlled Trial, Sarah Cooley, Brittany M Nelson, Alexander Rosenow, Elizabeth Westerhaus, W Todd Cade, Dominic N Reeds, Florin Vaida, Kevin E Yarasheski, Robert H Paul, Beau M Ances

2020-Current year OA Pubs

BACKGROUND: With the advent of antiretrovirals, people living with HIV are living near-normal lifespans. However, people living with HIV are at greater risk of experiencing cognitive impairment and reduced brain integrity despite well-controlled viremia. A robust literature supports exercise interventions as a method of improving cognition and structural brain integrity in older individuals without HIV. The effects of exercise on cardiometabolic, neurocognitive, and neural structures in middle-aged to older people living with HIV are less well known, with few prospective studies examining these measures.

OBJECTIVE: This prospective randomized clinical trial will examine the effects of a 6-month exercise training intervention …

On The Female Image In Walter Benjamin's Urban Studies, Lu Huang

Theoretical Studies in Literature and Art

Walter Benjamin's urban studies contain exquisite and comprehensive depictions of the female image. As a representative of dialectical images， the female figure， thanks to its ambivalence， demonstrates the rejection of dualism underlining the system of irony. This article analyzes Benjamin's thinking on the questions of sense and technology from the dialectical perspective of the female image in his urban studies. In Benjamin's writings， the re-enchanting feminine atmosphere engages such life experiences as gazing， caressing， and breathing， which allows the image of female mixed with that of animals to be connected to the senses of sight， hearing， touch and smell. The …

Qtl Analysis And Trait Dissection In Ryegrass (Lolium Spp.), T. Yamada, J. W. Forster

IGC Proceedings (1977-2023)

Key points

1. Molecular marker-based genetic analysis permits the dissection of complex phenotypes through resolution of the locations of pleiotropic and interacting genetic factors.
2. Several QTLs for agronomically important characters such as flowering time, winter hardiness and forage quality have been identified in perennial ryegrass by molecular marker-based map analysis.
3. Some QTLs were putatively orthologous to those for equivalent traits in cereals.
4. The identification of co-location between QTLs and functionally-associated genetic markers is critical for the future implementation of marker-assisted selection programs.

Leaves Of High Yielding Perennial Ryegrass Contain Less Aggregated Rubisco Than S23, A. Kingston-Smith, P. W. Wilkins

IGC Proceedings (1977-2023)

Breeding diploid perennial ryegrass for improved dry matter yield under nitrogen-limiting conditions has reduced the nitrogen (N) concentration of the herbage (Wilkins et al., 2003). Reduced N concentration in the ruminant diet is one potential way to reduce losses of N to the environment by reducing the amount of N that animals excrete. The underlying physiological basis of this increased N-use efficiency in ryegrass was investigated.

Variability In Quantity And Composition Of Water Soluble Carbohydrates Among Irish Accessions And European Varieties Of Perennial Ryegrass, S. Mcgrath, S. Barth, A. Frohlich, M. Francioso, S. A. Lamorte, T. R. Hodkinson

IGC Proceedings (1977-2023)

The objective of this study was to identify perennial ryegrass accessions displaying high fructose and glucose contents and an improved ratio between fructose and glucose fractions across different time points throughout the year. Fructose and glucose are the main constituents of the water soluble carbohydrate (WSC) fraction in perennial ryegrass. For animal nutrition the amount of WSC is crucial as it is the primary energy source available to metabolise the intake of plant protein. The ratio between fructose and glucose fractions is important since fructosan chains, which are an excellent energy source for ruminants, are built from fructose. Furthermore the …

The Influence Of Fertiliser Application To Strip-Sown Grasslands On Herbage Production And Quality, A. Kohoutek, P. Komárek, V. Odstrčilová, P. Nerušil

IGC Proceedings (1977-2023)

To increase the productivity of dairy cattle in the Czech Republic requires an improvement in herbage quality and an increase in the net energy of herbage. The decrease in cattle numbers by 50 % and the expansion of the grassland area both result in a surplus of feedstuffs of low quality. Introduction of strip-seeding of legumes and grasses into grasslands in interaction with fertilisation provides a possible solution to this problem.

Constraints On Dairy Cattle Production From Locally Available Forages In Bangladesh, M. A. S. Khan

IGC Proceedings (1977-2023)

The productivity of milk producing animals in Bangladesh is low because of low individual yield and poor fertility. The reasons for the low productivity are complex but, in order of priority, appear to be (a) the imbalanced nature of the nutrients that arise from the digestion of the forage resources, (b) the incidence of disease/parasitism, and (c) the often harsh climatic circumstances. Thus, the purpose of this study was to find out the practical constraints on dairy cattle production from locally available forages under small holding village conditions of Bangladesh.

The Rider (2023-03-20), Verilu Infante

The Rider Archives

Vol.8 No.23

Brain Volume, Energy Balance, And Cardiovascular Health In Two Nonindustrial South American Populations, Hillard Kaplan, Paul L. Hooper, Margaret Gatz, Wendy J. Mack, E. Meng Law, Helena C. Chui, M. Linda Sutherland, James D. Sutherland, Christopher J. Rowan, L. Samuel Wann, Adel H. Allam, Randall C. Thompson, David E. Michalik, Guido Lombardi, Michael I. Miyamoto, Daniel Eid Rodriguez, Juan Copajira Adrian, Raul Quispe Gutierrez, Bret A. Beheim, Daniel K. Cummings, Edmond Seabright, Sarah Alami, Angela R. Garcia, Kenneth Buetow, Gregory S. Thomas, Caleb E. Finch, Jonathan Stieglitz, Benjamin C. Trumble, Michael D. Gurven, Andrei Irimia

ESI Publications

Little is known about brain aging or dementia in nonindustrialized environments that are similar to how humans lived throughout evolutionary history. This paper examines brain volume (BV) in middle and old age among two indigenous South American populations, the Tsimane and Moseten, whose lifestyles and environments diverge from those in high-income nations. With a sample of 1,165 individuals aged 40 to 94, we analyze population differences in cross-sectional rates of decline in BV with age. We also assess the relationships of BV with energy biomarkers and arterial disease and compare them against findings in industrialized contexts. The analyses test three …

Phoebe Osgood, Saxophone, March 20, 2023 [Program], University Of Northern Iowa. School Of Music.

Music Recital Programs

Program of a music recital given by faculty, students, or guest artists from the School of Music at the University of Northern Iowa.

Experts Available To Comment On Climate Change And Urgency Of Environmental Concerns, Robbin Ray

Media Relations

No abstract provided.

To Ask Or Not To Ask? Dynamic Systems Perspective On Help Seeking In An Introductory Statistics Classroom, Bradley W. Bergey

Publications and Research

Student-generated questions are an important mechanism for learning and self-regulation, yet their scarcity in classroom discourse points to a need to understand how students decide to ask or withhold their questions. This study examined how 12 graduate students in an introductory statistics course made decisions about asking questions during whole group instruction. Help seeking decisions were framed as arising from a dynamic system of a student’s situated role identity as a class participant. Qualitative analysis of post-class interviews illustrated the highly contextual, dynamic nature of students’ decisions to ask or withhold questions. Analyses revealed an array of microdecisions that involved …

The V8-10 Variant Isoform Of Cd44 Is Selectively Expressed In The Normal Human Colonic Stem Cell Niche And Frequently Is Overexpressed In Colon Carcinomas During Tumor Development, Bruce M. Boman, Vignesh Viswanathan, Caroline O B Facey, Jeremy Z Fields, James W Stave

Kimmel Cancer Center Faculty Papers

CD44 protein and its variant isoforms are expressed in cancer stem cells (CSCs), and various CD44 isoforms can have different functional roles in cells. Our goal was to investigate how different CD44 isoforms contribute to the emergence of stem cell (SC) overpopulation that drives colorectal cancer (CRC) development. Specific CD44 variant isoforms are selectively expressed in normal colonic SCs and become overexpressed in CRCs during tumor development. We created a unique panel of anti-CD44 rabbit genomic antibodies to 16 specific epitopes that span the entire length of the CD44 molecule. Our panel was used to comprehensively investigate the expression of …

Echocardiography Parameters Used In Identifying Right Ventricle Dysfunction In Preterm Infants With Early Bronchopulmonary Dysplasia: A Scoping Review, Wisam Muhsen, Eirik Nestaas, Joanne Hosking, Jos M. Latour

Peninsula Medical School

Background Bronchopulmonary Dysplasia (BPD) is a chronic condition that affects preterm infants and is associated with long-term complications. Haemodynamic effects of BPD can lead to right ventricular (RV) dysfunction.ObjectiveTo synthesise and map the evidence of echo parameters used in identifying RV dysfunction in the first two weeks-after-birth (WAB) of preterm infants with early BPD.Information SourcesThis scoping review included the databases: Medline, CINAHL, PubMed, EMBASE, Scopus, ProQuest, Web of Science, Cochrane Library, JBI Evidence-Based Practise and Gray Literature.Search StrategyThe search utilised Boolean operators and descriptors registered in Medical Subject Headings.Inclusion and exclusion criteriaIncluded were studies utilising echo parameters to examine RV …

Biomarker Metabolite Discovery For Pancreatic Cancer Using Machine Learning, Immanuelle Kezia, Linda Erlina, Aryo Tedjo, Fadilah Fadilah

Indonesian Journal of Medical Chemistry and Bioinformatics

Pancreatic cancer is one of the deadliest cancers in the world. This cancer is caused by multiple factors and mostly detected at late stadium. Biomarker is a marker that can identify some diseases very specific. For pancreatic cancer, biomarker has been recognized using blood sample known as liquid biopsy, breath, pancreatic secret, and tumor marker CA19-9. Those biomarkers are invasive, so we want to identify the disease using a very convenient method. Metabolite is product from cell metabolism. Metabolites can become a biomarker especially from difficult diseases. In this paper, we want to find biomarker from metabolite using machine learning …