Digital Commons Network^™

Silver Carp Hypophthalmichthys Molitrix Movements In The Lower Cumberland And Lower Tennessee River, Miranda Belanger

Scholars Week

Silver Carp Hypophthalmichthys molitrix are an invasive species making up a large portion of the fish biomass in the lower portions of the Tennessee River and the Cumberland River. This species is expanding its range throughout the upper portions of these rivers, beginning with Kentucky Lake and Lake Barkley. Silver Carp rarely spawn in Kentucky Lake and Lake Barkley, but they can enter these reservoirs through the lock chamber. Thus, the bottleneck created by lock chambers can be used to control expansion of invasive Silver Carp. Although Silver Carp movement patterns have been studied in other portions of the Tennessee …

Adaptive Plasticity Of Coloration In Response To Environmental Change, Karissa Coffield

Scholars Week

When rapid environmental changes occur, different selective forces can create phenotypic trade-offs in which a trait can provide fitness benefits or costs under different environmental conditions. Amphibians are particularly vulnerable to environmental change, and previous research has revealed that some species will plastically respond to variation in temperature and ultra-violet radiation (UVR) by altering their coloration. Divergent selection on coloration may change with elevation and climate induced shifts in temperature because high temperatures are likely to result in lighter color morphs but as elevation increases, UVR exposure increases leading to the prediction that darker color morphs will be more common. …

Tú Dices “Plátano” Y Yo Digo “Mofongo”: Una Representación De La Normalización Del Biculturalismo En Alma’S Way, Jordan Carter

INSPIRE Student Research and Engagement Conference

Alma’s Way, a bilingual children’s animated television program from Fred Rogers Productions about a six year old Puerto Rican girl living in the Bronx of New York City with her family, premiered on PBS Kids in October 2021. Through the use of discourse analysis, this academic paper explores characters’ use of linguistic and cultural practices. Discourse analysis focuses on the main character, Alma, as well as her friends, her immediate family (Junior, Mami, Papi), and her mother’s side of the family (Abuelo, Tía Gloria, Uncle Nestor, Cousin Eddie). The analysis of 12 episodes chosen at random, a total of …

Information Literacy Education In The Digital Age: A Literature Survey, Peter Olubunmi Olubiyo, Lydia Mercy Olubiyo (Miss)

Library Philosophy and Practice (e-journal)

Across the world, educators in primary, secondary, tertiary and professional education contexts have been developing strategies and policies for designing learning opportunities that will enable learners to take advantage of the information literacy available to them. Learning opportunities that enhance information literacy not only make use of information and communication infrastructures, but to bring the information practices, that are effective in professional, civic and personal life into curriculum. Such opportunities make it possible for learners of all ages to experience the power of effective information literacy practices. When reflection on learning to be information literate is added to the experience …

Gene Discovery And Molecular Dissection Of Lignin Biosynthesis In Perennial Ryegrass (Lolium Perenne), A. Lidgett, M. Emmerling, R. Heath, R. Mcinnes, D. Lynch, A. Bartkowski, K. Fulgueras, T. Sawbridge, E. K. Ong, K. F. Smith, A. Mouradov, G. C. Spangenberg

IGC Proceedings (1977-2023)

Lignification of plant cell walls has been identified as a major factor limiting forage digestibility. It limits the amount of digestible energy available to livestock, resulting in an incomplete utilisation of cellulose and hemicellulose by ruminant animals. Modification of the lignin profile of ryegrasses (Lolium spp.) and fescues (Festuca spp.) is undertaken through modulating the expression of genes encoding enzymes involved in the biosynthesis of monolignols.

Identification Of Putative AtTt2 R2r3-Myb Transcription Factor Orthologues In Tanniferous Tissues Of L. Corniculatus Var. Japonicus Cv Gifu, D. N. Bryant, P. Bailey, P. Morris, Mark P. Robbins, C. Martin, T. Wang

IGC Proceedings (1977-2023)

R2R3-MYB plant transcription factors are sequence–specific DNA-binding proteins, which regulate the expression of specific gene(s) following the R2R3 DNA-binding domain interacting with the corresponding promoter sequence(s). The biosynthetic pathway leading to the production of anthocyanins has been demonstrated to be under MYB transcriptional regulatory control (Cone et al., 1986), while the accumulation of proanthocyanidins (PAs) in Arabidopsis seed coats is determined by the R2R3-MYB AtTT2 (Nesi et al., 2001). Using an informatics approach, partial sequences of putative AtTT2 orthologues have been identified and cloned from the forage legume Lotus corniculatus var. japonicus cv Gifu.

Comparative Evaluation Of The Antioxidant Activity, Trace Elements, And Phytochemical Analysis Of The Extracts Of Unripe Plantain Whole Fruit And Pulp, Damilare Emmanuel Rotimi, Oluyomi Stephen Adeyemi

Karbala International Journal of Modern Science

Plantains make a substantial contribution to food security and malnutrition eradication, thus making them a staple food in several tropical and subtropical climates. This research determined the mineral contents, antioxidant capacities and phytochemical constituents of plantain whole fruit (pulp and peel) and pulp extracts. To this end, the plantain samples were evaluated for their phytochemicals, mineral element content, and in vitro antioxidant properties. The phytochemical screening showed that the plantain whole fruit and pulp extracts contained phenols, terpenoids, flavonoids, cardiac glycosides, reducing sugars, alkaloids, and steroids. Tannins, on the other hand, were detected only in the plantain whole fruit extract. …

Role Of Microorganisms In Communication Between Soil And Plants, Domenico Prisa

Karbala International Journal of Modern Science

Microbial population in the rhizosphere establishes a number of important interactions with plants, whose study is crucial in perspective of sustainable agricultural production. Studies on various plant crops have revealed that, despite the complex microbial biodiversity of the soil, the bacterial microbiome is characterised by multiple functionalities. A better understanding of the molecular mechanisms, underlying the interactions between plants and the microbiome, could enable better development of plants, related to the beneficial action of microorganisms. Therefore, this review aims to describe the characteristics of the rhizosphere microbiome with the interactions that occur between soil and roots, as well as the …

The Echo: April 3, 2023, Taylor University

2022-2023 (Volume 110)

No abstract provided.

Rotunda - Vol 102, No 7 - Apr 3, 2023, Longwood University

Rotunda

No abstract provided.

Myod Functions As An Oncogene In Rhabdomyosarcoma By Promoting Survival Through Differentiation And Cyld, Alexander Oles

MUSC Theses and Dissertations

Rhabdomyosarcoma (RMS) is the most common soft tissue cancer among

children, characterized by a skeletal muscle lineage that is impaired from

undergoing terminal differentiation. NF-κB is constitutively active in cancer cells

and plays a critical role in cell survival. Although NF-κB is also activated in RMS,

surprisingly we find that these tumors are less dependent on NF-κB to overcome

stress-induced cell death. Instead, RMS cells survive by being partially

differentiated under the control of the myogenic transcription factor MyoD. Loss of

MyoD or cellular reprogramming dedifferentiates RMS tumor cells and promotes

cell death when exposed to stress. Further, use of …

Evaluating Draft Epa Emissions Models For Laying Hen Facilities, Yijie Xiong, Guoming Li, Brett C. Ramirez, Robert T. Burns, Richard S. Gates

Department of Animal Science: Faculty Publications

In August 2021, the U.S. Environmental Protection Agency (EPA) released draft models to estimate daily NH₃, H₂S, PM₁₀, PM_2.5, and TSP emissions from egg-layer houses (high-rise and manure-belt) and manure storage using inputs of daily mean ambient temperature, relative humidity (RH), and hen inventory. These models were developed from refined datasets generated by the National Air Emissions Monitoring Study fieldwork completed in 2009. Notably, they do not include data for cage-free housing. Currently, 66% of U.S. laying hens are housed in cages; thus, these models, if adopted, will have a substantial impact …

Taking Care Of Business: An Empirical Examination Of The Top S&P 500 Companies And Their Role As Public Health Regulators During The Covid-19 Pandemic, Megan M. O’Malley

University of Miami Business Law Review

Data from the top 15 constituents by weight on the S&P 500 is assembled to identify trends among the policies these companies implemented in the United States during the COVID-19 pandemic. Some policies were fairly consistent across the board, especially in regard to remote work opportunities and health and safety measures for essential and/or in-person employees. Other policies, including vaccination requirements and vaccine incentives, varied across and within industries. Some companies that were examined went beyond the relevant federal, state, or local requirements in effect at the time, while other companies pushed back against public health guidance.

Effects Of Pregnancy And Progesterone On Atrial Fibrillation, Heloisa M. Rutigliano

Browse all Datasets

Atrial Fibrillation (AF) is the most common cardiac arrythmia in adults with likely sex-specific risk factors. Female sex hormones may be important in modulating risk for atrial fibrillation. We hypothesize that pregnancy and progesterone (P4), a hormone found in high levels during pregnancy with abrupt withdrawal immediately after parturition, modulates AF susceptibility in female goats. Cardiac specific TGF-?1 transgenic female goats and age-matched wild-type (WT) female goats were utilized. Pacemakers were implanted in all animals for continuous arrhythmia monitoring and AF inducibility. AF inducibility was evaluated using 5 separate 10 s bursts of atrial pacing (160 - 200 ms). In …

Out With The Old, In With The New: Digital Interactive Journals In An Elementary Language Arts Methods Course, Kathleen M. Crawford, Heather M. Huling

Elementary & Special Education: Faculty Publications

In this article, two elementary literacy teacher educators provide elementary language arts content and methods by implementing digital interactive journals in a face-to-face classroom setting. The authors present how this practice evolved from traditional interactive journals pre-COVID to an innovative and engaging learning experience post-COVID. Interactive journals provide students with opportunities to explore and apply content and methods, while also learning a teaching strategy that pre-service teachers can implement in their own elementary classrooms. The authors describe the design and development of digital interactive journals along with student work samples and instructional steps to transfer and implement this strategy across …

Please Interact: Reworking A Digital Exhibit For Student Engagement Using "Free" Software, Claire Du Laney Dunker

Criss Library Faculty Proceedings & Presentations

In these increasingly post-pandemic and budgetary times, we at Archives and Special Collections are exploring dynamic ways of engaging audiences with our collection materials using resources, ie hardware and software that we have already or will require minimal costs.

One example of this, and the project I will be sharing about today, is an interactive exhibit of one of our collections that we display selected materials from on a large touch screen monitor located right outside the Archives and Special Collections department on the first floor of Criss Library.

In this presentation I will trace the history of how I …

Preparing Secondary Mathematics Preservice Teachers For Rural Schools In Colombia, Ricela Feliciano-Semidei, Mariana Alvayero Ricklefs, Yolima A. Rocha Fontalvo, Kevin A. Palencia Infante, R. BeltráN Hoyos

Faculty Articles, Papers, and Other Scholarship

This article describes a qualitative research case study that aimed to explore the complexity levels and types of mathematical thinking and national mathematics standards that a group of preservice teachers (PSTs) used to write mathematics word problems for secondary school students. The context was a teacher preparation course at a public university located in a rural region in Colombia, South America. The collected data included PSTs’ community reports, audio recordings of small-group discussions, and mathematics word problems. The data analysis process encompassed inductively created codebooks, several rounds of coding, and the inter-rater technique. The findings of the study demonstrated that …

News(?)Papers: A Typology Of Fake News, 1880-1920, Olivia G. Romaguera

LSU Master's Theses

“Fake news” is a malleable concept. It can be beaten and reshaped to fit many different contexts. One widely accepted definition of fake news is false information purporting itself to be factual. Another is information that is factual but called “fake” in order to discredit it. Concern over the spread of fake news increased in recent years. But preoccupation with what is happening today has left a gap in our understanding of the phenomenon, specifically its roots in the past. “Fake news” was present when news technology was relatively primitive; it is not essentially a function of such modern advancements …

Natural Lights & Natural Rights: The Problem Of The New Classical Natural Law Theory, Charles Neville Cacciatore

LSU Master's Theses

The present work examines the natural law jurisprudence of John Finnis. It argues that Finnis’s teaching is a genuinely new natural law theory. Finnis’s jurisprudence is not a re- presentation of the jurisprudence of St. Thomas Aquinas because its central element—a doctrine of natural rights—is a departure from Aquinas’s natural law teaching. In support of these claims, the present work relies upon the scholarship of Ernest L. Fortin, A.A. Following Fr. Fortin, it presents an understanding of the natural law that endorses a clear distinction between natural right and natural rights—between premodern political philosophy and modern political philosophy.

The Nature And Role Of Phenomenology In Hegel And Heidegger, Gabriel W. Connor

LSU Master's Theses

In this work I compare Hegel and Heidegger’s conception of phenomenology and its role in their thinking. Though these two thinkers are not often examined from this angle, and though there is controversy surrounding just how phenomenological each thinker might actually be, an examination of the two thinkers in this regard serves to identify interesting connections between Hegel and Heidegger while also raising questions about phenomenology in general. In short, I seek to establish that phenomenology in both Hegel and Heidegger is not adequately understood unless it is placed in the context of each thinker’s conception of human freedom along …

A Diverse Flea (Siphonaptera) Assemblage From The Small Mammals Of Central New Mexico, Dianne E. Peterson, Jonathan L. Dunnum, Schuyler W. Liphart, Karen A. Boegler, Ralph P. Eckerlin, Eric P. Hoberg, Martha O. Perez-Arriaga, Katrina Derieg, David Garnand, Mariel L. Campbell, Joseph A. Cook

MANTER: Journal of Parasite Biodiversity

The geographical ranges of many mammals and their associated parasites are dynamic. Comprehensive documentation of these communities over time provides a foundation for interpreting how changing environmental conditions, driven by accelerating climate change, other anthropogenic disturbances, and natural events, may influence host-parasite interactions. Fleas (Order Siphonaptera) are obligate, hematophagous parasites of birds and mammals with medical interest because of their role in transmitting pathogens. From 2016 to 2019, we sampled the small mammal and associated flea communities in El Malpais National Conservation Area (El Malpais) in Cibola County, New Mexico. Among 898 mammalian specimens, 925 fleas representing 29 species were …

Switch-Like Behavior Of Lysosomes And Vcp Supports Spermatocyte Health And Development In Drosophila, Tyler James Butsch

LSU Doctoral Dissertations

Changes to societal norms, such as the educational, marital, and child-bearing expectations have coincided with significant increases in infertility worldwide. Surprisingly, male infertility is responsible for approximately half of all infertility cases worldwide. Thus, a better understanding of sperm development, and how it is affected by age, may permit the design and application of therapeutics to treat various cases male infertility. Here, I have found that lysosomes acidify as germ cells enter the spermatocyte stage. Once active, lysosomes turn over E-cadherin, and likely other proteins, to support plasma membrane stability. Notably, aging negatively impacts lysosome acidification, which can be reversed …

Svip Dependent Tubular Lysosomal Restoration: A New Direction In Vcp Diseases, Ankita Basu

LSU Doctoral Dissertations

Multisystem Proteinopathy-1 (MSP-1) is a rare, autosomal dominant, degenerative disease resulting from single amino acid mis-sense mutations in the AAA+ ATPase, Valosin containing protein (VCP). Patients with VCP mutations vary widely in their pathology and clinical penetrance, making it difficult to devise effective treatment strategies. To investigate the pathology of VCP- related disease, we engineered CRISPR knock-in Drosophila models for nine MSP-1 associated VCP mutations. These mutant animals mimic human MSP-1 disease phenotypes, including progressive mobility decline and accumulation of protein aggregates, making them excellent models to study the pathology of VCP associated mutations and test potential treatment strategies. At …

Contribution Of The Microbiome On Reproductive Outcomes During Pregnancy, Kalie Beckers

LSU Doctoral Dissertations

A series of translational comparative studies were performed to investigate the effects of the maternal microbiome on reproductive function and outcomes. With the launch of the human microbiome project in 2007, the next generation sequencing of microbiomes is booming. It is not only in the human medicine field, but also in veterinary species. This study specifically investigates the fecal microbiome in blood pressure high sublime 5 (BPH/5) mouse model that spontaneously develops preeclampsia (PE) and obesity. Additionally, the equine reproductive tract microbiome was explored and compared to microbiome of other host body sites. The BPH/5 mouse is a translational model …

Pausing In American English: Documenting Native English Speakers' Pausing Patterns, Ammon Hunt

Theses and Dissertations

The purpose of this study was to examine more deeply the relationship between pause location and duration and its connection to clause and phrase boundaries for native English speakers (NESs). Previous research has shown pauses produced by NESs to be located at clause boundaries (Brown & Miron, 1971; Hawkins, 1971; Tavakoli, 2011), but little empirical work has been done to probe this issue further. For this research, 80 speech samples, 40 male and 40 female, were randomly selected from the International Dialects of English Archive (IDEA) representing different regions in the United States. Oral data from the read-aloud portion of …

Il6 Mediates Suppression Of T- And Nk-Cell Function In Emt-Associated Tki-Resistant Egfr-Mutant Nsclc, Sonia A Patel, Monique B Nilsson, Yan Yang, Xiuning Le, Hai T Tran, Yasir Y Elamin, Xiaoxing Yu, Fahao Zhang, Alissa Poteete, Xiaoyang Ren, Li Shen, Jing Wang, Seyed Javad Moghaddam, Tina Cascone, Michael Curran, Don L Gibbons, John V Heymach

Faculty, Staff and Student Publications

Purpose: Patients with advanced non-small cell lung cancer (NSCLC) harboring activating EGFR mutations are initially responsive to tyrosine kinase inhibitors (TKI). However, therapeutic resistance eventually emerges, often via secondary EGFR mutations or EGFR-independent mechanisms such as epithelial-to-mesenchymal transition. Treatment options after EGFR-TKI resistance are limited as anti-PD-1/PD-L1 inhibitors typically display minimal benefit. Given that IL6 is associated with worse outcomes in patients with NSCLC, we investigate whether IL6 in part contributes to this immunosuppressed phenotype.

Experimental design: We utilized a syngeneic genetically engineered mouse model (GEMM) of EGFR-mutant NSCLC to investigate the effects of IL6 on the tumor microenvironment and …

Dna Damage Repair Kinase Dna-Pk And Cgas Synergize To Induce Cancer-Related Inflammation In Glioblastoma, Clara Taffoni, Johanna Marines, Hanane Chamma, Soumyabrata Guha, Mathilde Saccas, Amel Bouzid, Ana-Luiza Chaves Valadao, Clément Maghe, Jane Jardine, Mi Kyung Park, Katarzyna Polak, Mara De Martino, Claire Vanpouille-Box, Maguy Del Rio, Celine Gongora, Julie Gavard, Nicolas Bidère, Min Sup Song, Donovan Pineau, Jean-Philippe Hugnot, Karima Kissa, Laura Fontenille, Fabien P Blanchet, Isabelle K Vila, Nadine Laguette

Faculty, Staff and Student Publications

Cytosolic DNA promotes inflammatory responses upon detection by the cyclic GMP-AMP (cGAMP) synthase (cGAS). It has been suggested that cGAS downregulation is an immune escape strategy harnessed by tumor cells. Here, we used glioblastoma cells that show undetectable cGAS levels to address if alternative DNA detection pathways can promote pro-inflammatory signaling. We show that the DNA-PK DNA repair complex (i) drives cGAS-independent IRF3-mediated type I Interferon responses and (ii) that its catalytic activity is required for cGAS-dependent cGAMP production and optimal downstream signaling. We further show that the cooperation between DNA-PK and cGAS favors the expression of chemokines that promote …

Induction Of Innate Inflammatory Pathways In The Corneal Epithelium In The Desiccating Stress Dry Eye Model, Zhiyuan Yu, Ghasem Yazdanpanah, Jehan Alam, Cintia S De Paiva, Stephen Pflugfelder

Faculty, Staff and Students Publications

PURPOSE: To determine whether 24-hour exposure to the desiccating stress (DS) dry eye model induces NF-kB and NLRP3 inflammasome pathways in the mouse cornea epithelium.

METHODS: Six- to 8-week-old C57BL/6J mice were housed under normal humidity (nonstressed) or subjected to DS from a drafty, low-humidity environment combined with subcutaneous scopolamine four times/day for one day to suppress tear production (DS1). Cornea whole mounts were prepared for immunofluorescent staining, or the corneal epithelium was scraped for NF-kB p-p65 ELISA, Western blot, or real-time PCR to detect NF-kB and inflammasome pathway proteins and gene transcripts, respectively.

RESULTS: NF-kB phospho-p65 protein, nuclear NF-kB …

Full Issue

Digressions: Literary & Art Journal

No abstract provided.

Alopecia In Patients With Collagen Vi-Related Myopathies: A Novel/Unrecognized Scalp Phenotype, Michela Starace, Francesca Pampaloni, Francesca Bruni, Federico Quadrelli, Stephano Cedirian, Carlotta Baraldi, Cosimo Misciali, Alberto Di Martino, Patrizia Sabatelli, Luciano Merlini, Bianca Maria Piraccini

Department of Dermatology and Cutaneous Biology Faculty Papers

Collagen VI-related myopathies are characterized by severe muscle involvement and skin involvement (keratosis pilaris and impaired healing with the development of abnormal scars, especially keloids). Scalp involvement and hair loss have not been reported among cutaneous changes associated with collagen VI mutations. The aim of this study is to describe the clinical, trichoscopic, and histological findings of the scalp changes in patients affected by COL VI mutations and to estimate their prevalence. Patients with Ullrich congenital muscular dystrophy were enrolled and underwent clinical and trichoscopic examinations and a scalp biopsy for histopathology. Five patients were enrolled, and all complained of …