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Evaluation Of Bone And Muscle Quality In Laying Hens Using Quantitative, Radiographic, Computed Tomographic, Biomechanical, And Tissue Level Measures, Cerano Harrison Aug 2023

Evaluation Of Bone And Muscle Quality In Laying Hens Using Quantitative, Radiographic, Computed Tomographic, Biomechanical, And Tissue Level Measures, Cerano Harrison

All Dissertations

Bone quality is an important measure of welfare in laying hens for researchers, veterinarians, and commercial producers who bear the responsibility of providing them with care. Breeding practices that have resulted in high egg productivity of laying hen strains have resulted in an increased susceptibility to developing osteoporosis. Osteoporosis, a decrease in mineralized bone, is accompanied by increased bone fragility that can lead to potentially painful bone fractures that can inhibit some aspects of the birds natural living, respiration and flight being two examples. Current methods of examining laying hen bone quality involve the implementation of diagnostic imaging and biomechanical …


Variability In Anesthesia And Its Implications For Improving Patient Safety, Joshua Michael Biro Aug 2023

Variability In Anesthesia And Its Implications For Improving Patient Safety, Joshua Michael Biro

All Dissertations

Improving patient safety in anesthesia has proven to be an arduous and challenging task. Despite the many strategies and interventions to improve patient safety that have been employed, patient harm in anesthesia remains a problem. The struggle to reduce patient harm in anesthesia is both attributable to and representative of the complexity of the anesthesia system. In navigating this complex system, anesthesia providers have different approaches to how they accomplish their work, which results in variability in anesthesia practice. This variability provides an immense challenge to designing and implementing efforts to improve patient safety, as rigid interventions are often met …


Protein A And Multimodal Anion-Exchange Membrane Adsorbers For Downstream Purification Of Therapeutic Biomolecules, Joshua Osuofa Aug 2023

Protein A And Multimodal Anion-Exchange Membrane Adsorbers For Downstream Purification Of Therapeutic Biomolecules, Joshua Osuofa

All Dissertations

This dissertation explores development and characterization of membrane chromatography tools for downstream purification of therapeutic biomolecules. Convective technologies, particularly membrane chromatography, are emerging in the field of bioseparations as an alternative to resin chromatography due to their improved throughput capability. On the forefront of emerging membrane technologies are multimodal and Protein A membrane adsorbers. The overarching theme of this dissertation research was to investigate advances in these membrane chromatography tools. The primary objective was to develop and characterize novel Protein A membrane adsorbers. A secondary objective was to characterize newly commercialized Protein A and multimodal anion exchange membrane adsorbers.

Two …


Biology And Herbicide Resistance Characteristics Of Various Annual Bluegrass (Poa Annua L.) Biotypes From Across The United States, Jacob William Taylor Aug 2023

Biology And Herbicide Resistance Characteristics Of Various Annual Bluegrass (Poa Annua L.) Biotypes From Across The United States, Jacob William Taylor

All Dissertations

Annual bluegrass (Poa annua L.) is one of the most problematic winter annual weeds in managed turfgrass systems, having rapidly adapted to different climates and management practices. Characteristics such as prolific seedhead production, clumped bunch-type growth habit, and lack of stress tolerance negatively impact turfgrass quality. Achieving adequate control can be difficult because annual bluegrass exhibits high levels of genetic diversity, the ability to germinate year-round, and has a high tendency for evolving herbicide resistance, currently resistant to at least nine different herbicide sites of action. Current management programs rely heavily on herbicides for control; however, frequent use without implementing …


Effect Of Authentic Kefir And Nigella Sativa On Broilers Challenged By Coccidia And Clostridium Perfringens, Julian E. Nixon Aug 2023

Effect Of Authentic Kefir And Nigella Sativa On Broilers Challenged By Coccidia And Clostridium Perfringens, Julian E. Nixon

All Dissertations

Black seed oil concentrations of 0%, 0.1%, 1% and 5% were added to milk inoculated with kefir grains and incubated at 25°C for 22 h. The pH and microbial count indicated 1% black seed oil caused low inhibition (P > 0.05) of fermentation, but 5% black seed oil caused significant inhibition of the kefir microorganisms (P < 0.05).

Cobb 500 male chicks (n = 256) were distributed in a randomized block design and received one of four treatments: CTRL1 (Non-medicated, no kefir, no Clostridium perfringens), CTRL2 (Non-medicated, no kefir, C. perfringens inoculated), CTRL3 (BMD medicated, no kefir, C. perfringens inoculated), KTRT (Non-medicated, …


Unruly Periods: Reproductive Futurities And The Rhetorics Of Menstruation, Hannah Taylor Aug 2023

Unruly Periods: Reproductive Futurities And The Rhetorics Of Menstruation, Hannah Taylor

All Dissertations

“Unruly Periods: Reproductive Temporalities and the Rhetorics of Menstruations” argues that dominant rhetorics of shame and regulation around menstruation work to maintain strict reproductive temporalities that uphold heteropatriarchal norms. Specifically, I draw upon scholarship in queer studies and disability rhetorics to assert that sexual health texts (such as puberty books), menstrual care products (pads and tampons), and technologies of menstruation (period-tracking apps) function as a form of chronobiolitics—a teleological force that seeks to reinforce bodily normalcy. In doing so, these rhetorics of menstruation deny or elide the embodied experiences of diverse, queer, and disabled menstruators, limiting reproductive possibilities. Reproductive justice …


Coming Home: Challenges Of Reintegration For Returned Migrant Women In Northern Albania, Marsida Tafilica Aug 2023

Coming Home: Challenges Of Reintegration For Returned Migrant Women In Northern Albania, Marsida Tafilica

All Dissertations

Return migration is the movement of people from host countries to their country of origin after spending a period of time abroad. The aim of this doctoral research is two-folded: Firstly, it aims to explore migration and return migration experiences of Albanian women in order to understand the difficulties experienced during and after migration and how they handled obstacles. Secondly, it analyzes how women migrants perceive successful reintegration.

Drawing on qualitative in-depth interviews of 19 Albanian women who returned to the city of Shkodra, the research seeks to answer the following questions: (1) Upon return, what are the perceptions of …


Improving Lignin Recovery From Paper Mill And Biorefinery Waste Streams Via Liquid-Phase Splitting, Carter Fitzgerald Aug 2023

Improving Lignin Recovery From Paper Mill And Biorefinery Waste Streams Via Liquid-Phase Splitting, Carter Fitzgerald

All Dissertations

Lignin is an abundant biopolymer with significant promise due to its aromaticity. It has been targeted as a replacement for a number of petroleum-based products including adhesives, coatings, polyurethane foams, activated carbon, and carbon fibers. However, commercially available bulk lignins are too polydisperse, and contain too many residual metals from the pulping process that are detrimental to the properties of the final product.

The Sequential Liquid-lignin Recovery and Purification (SLRP) process was developed by Michael Lake and John Blackburn, in collaboration with Clemson, with the intention of creating a continuous method for recovering lignin from paper-mill black liquors. Thies and …


The Risk Factors Associated With Personal Protective Equipment Usage Rates In The Central States By Generalized Multilevel Models, Carter E. Vogel Aug 2023

The Risk Factors Associated With Personal Protective Equipment Usage Rates In The Central States By Generalized Multilevel Models, Carter E. Vogel

Capstone Experience: Master of Public Health

Background: Agriculture producers in the United States face some of the highest rates of fatal and non-fatal injuries among all occupations. This includes a high risk of respiratory damage when working in dusty environments, chemical and health hazards when working with pesticides or other dangerous chemicals, and hearing damage when working in noisy environments. These risks can be reduced using personal protective equipment (PPE). While some workplaces are required by the Occupational Safety and Health Administration (OSHA) to provide necessary PPE and monitoring according to the risks of a job, many small farms are not required by OSHA to provide …


Assessing Meatpacking Worker's Perceptions Of Supervisors' Concern For Safety And Supervisors' Support, Sara Reyes Aug 2023

Assessing Meatpacking Worker's Perceptions Of Supervisors' Concern For Safety And Supervisors' Support, Sara Reyes

Capstone Experience: Master of Public Health

Occupational safety is a major public health issue, given that failure to meet safety regulations can lead to incidents and death. Meat processing facilities have some of the highest rates of non-fatal and fatal injuries compared to other industries. A reported 5.9 incidents per 100 full-time occupied within meat processing industries. The majority of workers within meat processing plants are people of color and immigrants, leading to a disproportion in reports of incidents and safety concerns. Immigrant workers frequently occupy positions within the kill floor and fabrication departments. Supervisors are often at the forefront of safety, yet workers often report …


Truth U, Justice U, Jesus U, Joseph Clair Aug 2023

Truth U, Justice U, Jesus U, Joseph Clair

Faculty Publications - George Fox School of Theology

Excerpt: "College and university professors in the liberal arts (humanities, social sciences, and natural sciences) are almost entirely left-leaning, liberal, or progressive, and this is especially true among faculty in the humanities and social sciences. Insofar as political party affiliation is representative, the statistics are stunning- roughly 12: I Democrat to Republican in the humanities and social sciences nationally, and this ratio is even more pronounced in certain selective schools (Brown University takes the cake with 60:1).1 Students who attend liberal arts colleges or universities (that is, non-trade, nonvocational schools that require core curricula and keep an array of majors …


Evaluation Of A First Flush System With Multiple In-Line Bypassing Fuel Separator Components In The Industrial Area Of An Airport, Kazi Rashid Aug 2023

Evaluation Of A First Flush System With Multiple In-Line Bypassing Fuel Separator Components In The Industrial Area Of An Airport, Kazi Rashid

Civil Engineering Dissertations - Archive

ABSTRACT: This dissertation explores the effectiveness of a complex system employed to capture the first flush (FF) generated from industrial activities occurring at an airport. The First Flush System (FFS) utilized by the DFW International Airport is comprised of multiple in-line bypassing fuel separators and located in many parts of the Air Operations Area (AoA) of the airport as well as maintenance areas. The system collects and conveys a portion of the rainfall runoff generated from the drainage areas of the industrial land-use portion of the DFW airport to a Stormwater Pre-treatment Plant (SWPTP) and then to Trinity River Authority …


The Impact Of Improper Solid Waste Management On Public Health Of African Cities. The Case Of Addis Ababa City, Ethiopia., Tesfaye Abebe Alemu Aug 2023

The Impact Of Improper Solid Waste Management On Public Health Of African Cities. The Case Of Addis Ababa City, Ethiopia., Tesfaye Abebe Alemu

Civil Engineering Dissertations - Archive

Many African cities are generating an ever-increasing amount of waste and the effectiveness of their solid waste collection and disposal systems is currently declining. Therefore, research has been striving to develop a sustainable and integrated solid waste management system that fits the current challenges facing the local environment. The objective of this study is to analyze the impact of improper solid waste management that affects the air and water quality of the near Koshe open dump site and around the Addis Ababa City, and their adverse effect on the public health living around them. The rapid increase of population in …


The Road Map For Sustainable Waste Management In The Federal Democratic Republic Of Ethiopia, Assegid Yimenu Aug 2023

The Road Map For Sustainable Waste Management In The Federal Democratic Republic Of Ethiopia, Assegid Yimenu

Civil Engineering Dissertations - Archive

Solid Waste Management (SWM) is a global issue from its social, environmental, and economic aspects. Poor SWM is one of the significant causes of resource degradation, environmental pollution, and public health problems. In this study, households’ solid waste generation and characterization were determined for selected cities in Ethiopia. Quantitative and qualitative study methods were applied to collect primary and secondary data to assess the household’s MSW generation rate and characterize the waste type's physical composition. The households’ daily MSW generation rates in Bole and Kirkos sub-cities, Addis Ababa, were found to be 0.54 and 0.26 Kg/capita/day, respectively, and the average …


Pitfalls In Machine Learning-Based Assessment Of Tumor-Infiltrating Lymphocytes In Breast Cancer: A Report Of The International Immuno-Oncology Biomarker Working Group On Breast Cancer, Jeppe Thagaard, Glenn Broeckx, Chowdhury Arif Jahangir, Sara Verbandt, Rajarsi Gupta, Reena Khiroya, Khalid Abduljabbar, Gabriela Acosta Haab, Balazs Acs, Shahin Sayed Aug 2023

Pitfalls In Machine Learning-Based Assessment Of Tumor-Infiltrating Lymphocytes In Breast Cancer: A Report Of The International Immuno-Oncology Biomarker Working Group On Breast Cancer, Jeppe Thagaard, Glenn Broeckx, Chowdhury Arif Jahangir, Sara Verbandt, Rajarsi Gupta, Reena Khiroya, Khalid Abduljabbar, Gabriela Acosta Haab, Balazs Acs, Shahin Sayed

Pathology, East Africa

Abstract: The clinical significance of the tumor-immune interaction in breast cancer is now established, and tumor-infiltrating lymphocytes (TILs) have emerged as predictive and prognostic biomarkers for patients with triple-negative (estrogen receptor, progesterone receptor, and HER2-negative) breast cancer and HER2-positive breast cancer. How computational assessments of TILs might complement manual TIL assessment in trial and daily practices is currently debated. Recent efforts to use machine learning (ML) to automatically evaluate TILs have shown promising results. We review state-of-the-art approaches and identify pitfalls and challenges of automated TIL evaluation by studying the root cause of ML discordances in comparison to manual TIL …


Spatial Analyses Of Immune Cell Infiltration In Cancer: Current Methods And Future Directions: A Report Of The International Immuno-Oncology Biomarker Working Group On Breast Cancer, David Page, Chowdhury Jahangir, Sara Verbandt, Rajarsi Gupta, Jeppe Thagaard, Reena Khiroya, Zuzana Kos, Khalid Abduljabbar, Sunil Badve, Shahin Sayed Aug 2023

Spatial Analyses Of Immune Cell Infiltration In Cancer: Current Methods And Future Directions: A Report Of The International Immuno-Oncology Biomarker Working Group On Breast Cancer, David Page, Chowdhury Jahangir, Sara Verbandt, Rajarsi Gupta, Jeppe Thagaard, Reena Khiroya, Zuzana Kos, Khalid Abduljabbar, Sunil Badve, Shahin Sayed

Pathology, East Africa

Abstract: Modern histologic imaging platforms coupled with machine learning methods have provided new opportunities to map the spatial distribution of immune cells in the tumor microenvironment. However, there exists no standardized method for describing or analyzing spatial immune cell data, and most reported spatial analyses are rudimentary. In this review, we provide an overview of two approaches for reporting and analyzing spatial data (raster versus vector-based). We then provide a compendium of spatial immune cell metrics that have been reported in the literature, summarizing prognostic associations in the context of a variety of cancers. We conclude by discussing two well-described …


Examining The Effects Of Iron-Oxide Nanoparticles On Primary Gingival Keratinocytes For The Prevention Of Oral Disease, Jennifer C. Carranza Aug 2023

Examining The Effects Of Iron-Oxide Nanoparticles On Primary Gingival Keratinocytes For The Prevention Of Oral Disease, Jennifer C. Carranza

Dental Hygiene ETDs

Oral plaque biofilm has been identified as the primary contributor to dental conditions such as dental caries and periodontal disease that promotes a diverse and pervasive collection of microbial species to inhabit the oral cavity. Disrupting the plaque matrix early could help combat this global disease burden. This study evaluated the effect of IONPs on primary gingival keratinocytes.

Purpose: This study aimed to examine existing research regarding nanoparticles and determine if IONPs affect the PGK cell membranes with preliminary research to find the maximum lysis possible with PGK cells.

Methods: IONP core/shell syntheses were performed. Considering keratinocyte characteristics, examining data …


Faults Segmentation In Levee Systems Using Deep Learning Approaches, Manisha Panta Aug 2023

Faults Segmentation In Levee Systems Using Deep Learning Approaches, Manisha Panta

LSU New Orleans Theses and Dissertations

Levees are earthen structures constructed to mitigate flooding in low-lying areas. Although levee systems can reduce flood risks, they cannot completely eliminate them. Failures within flood control systems due to inadequate maintenance or strong water currents can lead to significant property damage and catastrophic loss of life, as was seen during Hurricane Katrina. Consequently, regular inspections are essential to identify and address any issues with the levees promptly. However, current inspection methods rely on manual techniques that are time-consuming, labor-intensive, and prone to human error. Therefore, this study proposes using deep learning models for more efficient and frequent assessment of …


The Role Of Shame In The Relationships Among Childhood Maltreatment, Fears Of Evaluation, And Associated Submissive Behaviors, Savannah Woods Aug 2023

The Role Of Shame In The Relationships Among Childhood Maltreatment, Fears Of Evaluation, And Associated Submissive Behaviors, Savannah Woods

Masters Theses and Doctoral Dissertations

Risk for excessive fears of evaluation in adulthood may increase with severity of exposure across five sub-domains of childhood maltreatment. Childhood exposure to childhood maltreatment may increase risk for behaviors associated with fear of negative evaluation (FNE) and fear of positive evaluation (FPE), such as submissive behavior displays (e.g., eye gaze avoidance). Additionally, previous literature (while limited) suggests that negative affect, especially shame, may play an influential role in the relationship between overall childhood maltreatment history severity and fears of evaluation in adulthood. Shame has the potential to increase FNE and FPE along with associated behaviors (i.e., gaze avoidance). The …


Developing A Predictive Geospatial Habitat Model For A Rare Species Of Salamander In Tennessee: A Case Study For The Green Salamander (Aneides Aeneus), Erin Gaylord Aug 2023

Developing A Predictive Geospatial Habitat Model For A Rare Species Of Salamander In Tennessee: A Case Study For The Green Salamander (Aneides Aeneus), Erin Gaylord

Masters Theses and Doctoral Dissertations

Green Salamanders (Aneides aeneus; Cope and Packard 1881) are a secretive and cryptic species of salamander that can be relatively difficult to detect, due to their occupation of arboreal habitats. The incorporation of geospatial tools is critical in developing models that can be used to predict undocumented locations in Tennessee and elsewhere. Locating the species in Tennessee was accomplished through a total of 18 localities and with that, several habitat characteristics were able to be identified including, but not limited to: appropriately shaded and structured rocks, typical fauna co-occurring within the area, and general topography of the area. Of the …


Degradation Of Indigo Dye Using Quantum Mechanical Calculations, Halla T. Mohammed, Ahmed M. Kamil, Hayder M. Abduljalil, Abbas A- Ali Drea, Mohammed A. Al-Seady Aug 2023

Degradation Of Indigo Dye Using Quantum Mechanical Calculations, Halla T. Mohammed, Ahmed M. Kamil, Hayder M. Abduljalil, Abbas A- Ali Drea, Mohammed A. Al-Seady

Baghdad Science Journal

The semiempirical (PM3) and DFT quantum mechanical methods were used to investigate the theoretical degradation of Indigo dye. The chemical reactivity of the Indigo dye was evaluated by comparing the potential energy stability of the mean bonds. Seven transition states were suggested and studied to estimate the actually starting step of the degradation reaction. The bond length and bond angle calculations indicate that the best active site in the Indigo dye molecule is at C10=C11. The most possible transition states are examined for all suggested paths of Indigo dye degradation predicated on zero-point energy and imaginary frequency. The first starting …


Using Microalga Coelastrella Sp. To Remove Some Nutrients From Wastewater Invitro, Muzhda Qasim Qader, Yahya Ahmed Shekha Aug 2023

Using Microalga Coelastrella Sp. To Remove Some Nutrients From Wastewater Invitro, Muzhda Qasim Qader, Yahya Ahmed Shekha

Baghdad Science Journal

Microalgae have been increasingly used for wastewater treatment due to their capacity to assimilate nutrients. Samples of wastewater were taken from the Erbil wastewater channel near Dhahibha village in northern Iraq. The microalga Coelastrella sp. was used in three doses (0.2, 1, and 2g. l-1) in this experiment for 21 days, samples were periodically (every 3 days) analyzed for physicochemical parameters such as pH, EC, Phosphate, Nitrate, and BOD5, in addition to, Chlorophyll a concentration. Results showed that the highest dose 2g.l-1 was the most effective dose for removing nutrients, confirmed by significant differences (p≤0.05) between all doses. The highest …


University Of Central Florida Graduate Catalog, 2023 - 2024, University Of Central Florida Aug 2023

University Of Central Florida Graduate Catalog, 2023 - 2024, University Of Central Florida

UCF Catalogs

No abstract provided.


Yala Designs Marketing Strategy, Anna Buckley Aug 2023

Yala Designs Marketing Strategy, Anna Buckley

Finance Undergraduate Honors Theses

This paper dives into the complexities of a sustainable pajama company's social media marketing strategy. This paper also analyzes the strategies of competitors and market leaders in an attempt to formulate suggested strategies based off their success.


Students Gain Experience In Computer Science Technology At Gardner-Webb Camp, Office Of University Communications Aug 2023

Students Gain Experience In Computer Science Technology At Gardner-Webb Camp, Office Of University Communications

Gardner-Webb NewsCenter Archive

Madelyn Hicks, a high school junior, proudly held out the decorative cup she made with a 3D printer. A participant in the Stonecutter Foundation Computer Science Camp at Gardner-Webb University, she shared how she created the object and learned about 3D animation.


A Novel Brain Computer Interface Design, Steven Vogan Aug 2023

A Novel Brain Computer Interface Design, Steven Vogan

Senior Honors Theses

A brain computer interface (BCI) is a system which connects neural signals to a computer system. They have been used for controlling systems including robotics, on-screen computer control such as mouse movement, typing, and synthesizing audio signals. Invasive, or implanted, systems are often long-term medical solutions, or used for research where very clear signal is required. Non-invasive systems usually rely on exterior signals gathered through a headset using one or more electrode sensors. These signals are composed of sums of neuron activation potentials from brain activity and can be used to determine particular aspects of brain function. All BCIs rely …


Silala River Case: The Equitable Utilization Right And The Issues Of Water Commodification And Artificial Flows, Agnes Chong Aug 2023

Silala River Case: The Equitable Utilization Right And The Issues Of Water Commodification And Artificial Flows, Agnes Chong

Wyoming Law Review

No abstract provided.


Investigation Of Orthohantavirus Genetics In Rodent Reservoirs And Clinical Samples, Samuel Melvin Goodfellow Aug 2023

Investigation Of Orthohantavirus Genetics In Rodent Reservoirs And Clinical Samples, Samuel Melvin Goodfellow

Biomedical Sciences ETDs

Orthohantaviruses are negative-sense, single stranded RNA viruses with trisegmented genomes that can cause severe disease in humans and are carried by several host reservoirs throughout the world. In the United States, Sin Nombre orthohantavirus (SNV) is the primary cause of hantavirus cardiopulmonary syndrome (HCPS) with a fatality rate of ~36% and the highest cases occuring in the southwest region. The primary SNV host reservoir is thought to be the western deer mouse, Peromyscus maniculatus, however it has been shown that other rodents can carry different orthohantaviruses. We designed a pan-orthohantavirus detection tool to survey several small mammal populations throughout New …


Longitudinal Assessment Of Cognitive Function In The Appswe/Ps1de9 Mouse Model Of Alzheimer's-Related Beta-Amyloidosis, Paul L. Soto, Michael E. Young, Giuliana M. Dimarco, Brianna George, Tatiana Melnikova, Alena V. Savonenko, Breanna N. Harris Aug 2023

Longitudinal Assessment Of Cognitive Function In The Appswe/Ps1de9 Mouse Model Of Alzheimer's-Related Beta-Amyloidosis, Paul L. Soto, Michael E. Young, Giuliana M. Dimarco, Brianna George, Tatiana Melnikova, Alena V. Savonenko, Breanna N. Harris

Faculty Publications

Preclinical models of Alzheimer's disease (AD)-related cognitive decline can be useful for developing therapeutics. The current study longitudinally assessed short-term memory, using a delayed matching-to-position (DMTP) task, and attention, using a 3-choice serial reaction time (3CSRT) task, from approximately 18 weeks of age through death or 72 weeks of age in APPswe/PS1dE9 mice, a widely used mouse model of AD-related amyloidosis. Both transgenic (Tg) and non-Tg mice exhibited improvements in DMTP accuracy over time. Breaks in testing reduced DMTP accuracy but accuracy values quickly recovered in both Tg and non-Tg mice. Both Tg and non-Tg mice exhibited high accuracy in …


The Vagus Nerve Mediates Gut-Brain Response To Duodenal Nutrient Administration, Robert C. Ross, Yanlin He, R. Leigh Townsend, Philip R. Schauer, Hans Rudolph Berthoud, Christopher D. Morrison, Vance L. Albaugh Aug 2023

The Vagus Nerve Mediates Gut-Brain Response To Duodenal Nutrient Administration, Robert C. Ross, Yanlin He, R. Leigh Townsend, Philip R. Schauer, Hans Rudolph Berthoud, Christopher D. Morrison, Vance L. Albaugh

Division of Basic Science Faculty Publications

Background: Obesity contributes significant disease burden worldwide, including diabetes, cardiovascular disease, and cancer. While bariatric surgery is the most effective and durable obesity treatment, the mechanisms underlying its effects remain unknown. Although neuro-hormonal mechanisms have been suspected to mediate at least some of the gut-brain axis changes following bariatric surgery, studies examining the intestine and its regionally specific post-gastric alterations to these signals remain unclear. Materials and methods: Vagus nerve recording was performed following the implantation of duodenal feeding tubes in mice. Testing conditions and measurements were made under anesthesia during baseline, nutrient or vehicle solution delivery, and post-delivery. Solutions …