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Centering Indigenous Knowledge: Reimagining Research Methods, Pedagogies, And Sustainability With Niitsitapi Awaaáhsskataiksi (Blackfoot Elders), Sandra Bartlett Atwood

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

My research sought to better engage with Indigenous ways of knowing and being (IWKB). Specifically, I collaborated with Blackfoot Elders (and Hawaiian Kupuna) to better understand 1) their perspectives towards land, 2) what factors instigate and perpetuate these perspectives, 3) how these perspectives play out in terms of identity; well being; daily life; education; environmental concern, behavior, and stewardship, and 4) ways that these perspectives towards land can inform and transform Western perspectives on land and perhaps lead to better and more equitable social-ecological outcomes. I approached this from three angles. First, I described a method for braiding Indigenous and …

What Influences Green Cosmetics Purchase Intention And Behavior? A Systematic Review And Future Research Agenda, Yam B. Limbu, A. F.M.Jalal Ahamed

Department of Marketing Faculty Scholarship and Creative Works

The green cosmetics industry has witnessed significant growth over the last few years. Simultaneously, scholarly interest in the area has grown. However, overall, the evidence is inconsistent. Despite the growing literature, no systematic review has been carried out to summarize and synthesize the empirical studies that have examined factors associated with green cosmetics purchase intention (GCPI) and green cosmetics purchase behavior (GCPB). This study aims to fill this gap. We conducted this systematic review following the PRISMA guidelines. From forty-eight studies that met the inclusion criteria, we identified ten major themes that were significantly associated with GCPI and GCPB. The …

Novel Insights Into Oligodendrocyte Biology From Developmental Myelination Studies In Autophagy Deficient Mice And Analysis Of Oligodendrocyte Translatome Response To Contusive Spinal Cord Injury., Michael David Forston

Electronic Theses and Dissertations

Loss of myelin causes severe neurological disorders and functional deficits in white matter injuries (WMI) such as traumatic spinal cord injury (SCI). This dissertation is focused on autophagy in OL development and the OL translatome after SCI. Chapter I describes the history of myelin, OL development, and their involvement in neurodegenerative diseases and SCI. The proteostasis network, in particular autophagy, and its contributions to white matter pathology is discussed. It concludes examining advantages and disadvantages of unbiased omics tools, like RiboTag, to study transcriptional/translational landscapes after SCI. Chapter II focuses on autophagy in OPC/OL differentiation, survival, and proper myelination in …

Sex-Specific Responses To Gnrh Challenge, But Not Food Supply, In Kittiwakes: Evidence For The “Sensitivity To Information” Hypothesis, Shannon Whelan, Z Morgan Benowitz-Fredericks, Scott A. Hatch, Charline Parenteau, Olivier Chastel, Kyle H. Elliott

Faculty Journal Articles

Seasonal timing of breeding is usually considered to be triggered by endogenous responses linked to predictive cues (e.g., photoperiod) and supplementary cues that vary annually (e.g., food supply), but social cues are also important. Females may be more sensitive to supplementary cues because of their greater role in reproductive timing decisions, while males may only require predictive cues. We tested this hypothesis by food-supplementing female and male colonial seabirds (black-legged kittiwakes, Rissa tridactyla) during the pre-breeding season. We measured colony attendance via GPS devices, quantified pituitary and gonadal responses to gonadotropin releasing hormone (GnRH) challenge, and observed subsequent laying phenology. …

Public Space And Well-Being: An Empirical Study Of Central Park In Old Louisville., Maryam Entezam

Electronic Theses and Dissertations

Urban green spaces have been receiving attention in urban planning and the health profession in the 21^st century as environmental elements that contribute to well-being. This dissertation explored the relationship between green space usage and individuals’ physical, mental, and social well-being. This empirical research focused on Central Park in Old Louisville to examine how residents use the park and whether it contributes to the well-being of residents. After exploring the existing literature, I identified four well-being indices: (1) perceived health (PHI), (2) health outcome (HOI), (3) mental well-being (MWI), and (4) social well-being (SWI). Frequent Park usage is expected …

The Relationship Between Poverty And Behavior Problems : Examining The Role Of Family And Parental Factors From An Ecological Systems Perspective, Alaina Marie Wodzinski

Theses, Dissertations and Culminating Projects

The large number of children from low-income households or living in poverty are at increased risk for a range of negative outcomes, including behavior problems. The Family Stress Model is a framework that can be used to describe how poverty may shape the development of behavior problems through its influence on family processes, including parental mental health, parenting, and household environment. While the Family Stress Model has been widely replicated, studies have rarely examined the context of infancy and toddlerhood, during which family-related processes tend to be more impactful in child development. Therefore, the present study evaluated two adaptations of …

Histamine Excretion In Common Indoor And Hematophagous Arthropods, Simona Principato, Alvaro Romero, Chow-Yang Lee, Kathleen Campbell, Dong-Hwan Choe, Coby Schal, Zachary C. Devries

UK CARES Faculty Publications

Histamine is a biogenic amine that regulates multiple physiological functions in diverse organisms, specifically playing a central role in the mammalian immune response. The common bed bug, Cimex lectularius L. (Hemiptera: Cimicidae), excretes histamine in large amounts in its feces as a component of its aggregation pheromone, which contaminates homes. The potential health risks associated with the presence of indoor histamine are unclear, but to predict future exposure risks, it is critical that we understand if other arthropods excrete histamine in any discernible phylogenetic pattern. In the present study, we evaluated histamine excretion by various arthropods; specifically those commonly found …

Effect Of Exercise Training On Circulating Cancer-Associated Immune Cells In Breast Cancer Patients, Lea Haverbeck Simon

Dissertations

Breast cancer (BC) is one of the leading causes of cancer deaths among females. It is well known that the presence of a tumor decreases robust anticancer immunity via immune-modulation and enhanced immunosuppression through a process called cancer immunoediting. However, it has yet to be determined if exercise-based rehabilitation can elevate the peripheral anticancer immune profile and reduce myeloid-derived suppressor cell (MDSC) mediated immunosuppression. Purpose: To assess the effects of a 12-week prescribed, individualized, supervised exercise-based rehabilitation program on selected circulating immune cells in BC patients at the University of Northern Colorado Cancer Rehabilitation Institute. Methods: 16 female BC patients …

Microstructural Characterization Of High-Protein Dairy Powders, Prafulla Salunke, Athira Syamala, Lloyd Metzger

Dairy Science and Food Science Faculty Publications: 2022 to Present

Dairy proteins are potential and multipurpose ingredients used to prepare various food products. It exhibits many beneficial functionalities and bioactivities in the processing of food products. All the functionalities of different dairy proteins depend on their peculiar structural characteristics. So, the present study aimed to characterize high-protein powders with different matrices (milk protein concentrate (MPC), rennet casein (RCN), micellar casein concentrate (MCC), whey protein isolate (WPI), and native whey concentrate (NWC)) for their composition, handling, and reconstitution properties, and microstructure and compared them with whole milk powder (WMP) and skim milk powder (SMP). The bulk density of the high-protein powders …

Underneath It All: Uncanny Sounds, The Materiality Of The City Through The Ear Of The Other, Patrick Fuery

CCI Articles and Research

"One of the intricate connections that shapes urban spaces is made through the interweaving of divergent, competing, and complimenting sounds. Just as objects, inhabitants, and histories form urban spaces, there is also an aurality that defines each one, distinguishing it from all others. The flows and ripples of these different soundscapes simultaneously challenge the separations of urban spaces and reinforce the distinctions. At the most overt, these are the sounds of the market as they exceed the spatial boundaries and mix with traffic noises; the softer sounds of the park that muffle and hold construction clamor; the multicultural voices as …

Effects Of The Covid-19 Pandemic On Humeral Shaft Fracture Management And Its Outcomes., Chrystina L. James, Trevor D. Wolterink, Bushra Fathima, Gabriel B. Burdick, Susan G. Wager, Jager W. Haan, Yash D. Hegde, Stephanie Muh

Orthopedics Articles

Background and objective: The coronavirus disease 2019 (COVID-19) pandemic necessitated a sudden and drastic shift in patient management throughout the healthcare system, to curb the spread of the disease and deal with resource limitations. Many surgical cases were canceled or delayed with only the most urgent and emergent cases taken up for treatment. It is unknown if and how these alterations affected patient outcomes. The purpose of this study was to compare time to fracture care and outcomes between patients treated for humeral shaft fractures prior to the COVID-19 pandemic and those treated during the pandemic. We hypothesized that the …

Voluntary Action And Conscious Intention, Jake Gavenas

Computational and Data Sciences (PhD) Dissertations

Traditional experimental methodology in neuroscience involves comparing responses to different stimuli to make inferences about the human brain. However, human volition entails making decisions and acting in a manner that is underdetermined by the external environment. Investigations of the neuronal basis of volition have led to new controversies regarding the existence of free will, and offer potential directions for medical treatments of disorders such as addiction, akinetic mutism, and locked-in syndrome. However, because volition experiments leave aspects of responses “up to” participants, neuroscientists must utilize computational techniques such as modeling, simulation, and advanced analyses to progress our understanding of human …

A Systems Genetics Approach To Drosophila Melanogaster Models Of Rare And Common Neurodevelopmental Disorders, Rebecca Macpherson

All Dissertations

Fetal Alcohol Spectrum Disorders are a group of disorders resulting from prenatal alcohol exposure, presenting with neurodevelopmental and facial abnormalities of varying severity. SSRIDDs and CdLS are rare disorders of chromatin modification, resulting in patients with a wide range of craniofacial, digit and/or neurodevelopmental abnormalities. All of these disorders have a wide range of clinical phenotypes and disease severity, yet the role of potential genetic modifiers and gene-gene or gene-environment interactions in disease pathogenesis is largely unknown and cannot be studied in humans. Insufficient numbers of patients with a single rare disorder prevent investigation of genetic factors beyond the focal …

Purdue Imaging Facility, Purdue University Office Of Research, Xiaoguang Zhu

University Research Core Facility Boilerplate Descriptions

No abstract provided.

Biodiversity In The Anthropocene, Understanding The Impacts Of Land-Use Change, And Species Interactions., Alexander H. Murray

Biology Dissertations - Archive

The extent of human influences on the environment and biodiversity has led to naming our current time period the Anthropocene. A primary way in which humans impact biodiversity is through habitat modification. Despite the knowledge that habitat modification is negative for many species, we still don’t understand why some species are able to persist despite habitat modification while others do not. In my first chapter I used a trait-based approach to understand what determines species’ sensitivity to habitat modification. Trait-based approaches from different regions often disagree on the importance of the same traits, and I thought climate and land use …

Determining How Anthropogenic Change Filters Biological Communities And How Species Modify Their Traits In Response To Urbanization, Kristopher Warren Row

Biology Dissertations - Archive

Humans are significantly altering the environment at an alarming pace, leading to a reduction in species diversity. This transformation has created modified habitats where some species struggle to survive, while a few others not only manage to survive but thrive. One of the most drastic forms of habitat modification is urbanization, which is spreading worldwide and contributing to the decline of biodiversity. Urbanization has given rise to urban-tolerant species that differ ecologically from species that avoid urban areas across various niche dimensions. These urban-tolerant species must adapt to changes in food sources, microhabitat conditions, and alterations in physical habitat structures. …

The Antiviral Effects Of A Mek1/2 Inhibitor Promote Tumor Regression In A Preclinical Model Of Human Papillomavirus Infection-Induced Tumorigenesis, Adrian J. Luna, Jesse M. Young, Rosa T. Sterk, Virginie Bondu, Fred A. Schultz, Donna F. Kusewitt, Huining Kang, Michelle A. Ozbun

Pathology Research and Scholarship

Human papillomaviruses (HPVs) are a significant public health concern due to their widespread transmission, morbidity, and oncogenic potential. Despite efficacious vaccines, millions of unvaccinated individuals and those with existing infections will develop HPV-related diseases for the next two decades and beyond. The continuing burden of HPV-related diseases is exacerbated by the lack of effective therapies or cures for infections, highlighting the need to identify and develop antivirals. The experimental murine papillomavirus type 1 (MmuPV1) model provides opportunities to study papillomavirus pathogenesis in cutaneous epithelium, the oral cavity, and the anogenital tract. However, to date the MmuPV1 infection model has not …

On-Line Environment Adaptation For User Performance Optimization, Subharag Sarkar

Computer Science and Engineering Dissertations - Archive

In today’s fast-paced and globally connected world, businesses are creating products with more significance to user personalization and customization. This has amplified the importance of capturing and learning user preferences as more information from users can lead to the designing and development of products that will improve user engagement and performance. Numerous algorithms based on collaborative filtering and recommender systems have been used to learn user preferences, but almost all of them require big datasets to train on. This creates a dependency on collecting more and more user information which might lead to ethical considerations and privacy concerns. To solve …

The Applicability Of Lessons From American Society For The European Union: Tolerance, Demographic Change, And Social Structure, Joseph Drew

Comparative Civilizations Review

While Americans have long tended to see our society and civilization as exceptional, in fact the civilization is primarily based on European precedent. We see ourselves, in the words of one of our most significant poets, Emma Lazarus, as the new colossus, “Keep, ancient lands, your storied pomp cries she... I lift my lamp beside the golden door.” We claim to be an exception; that means that we are unique, different, what many, alluding to the New Testament as viewed by the Pilgrim founding fathers, have called “a shining city upon a hill.”2 And as “a beacon of hope.”

The Economic Regions Of Chinese Civilization: A Gis-Based Analysis Of Grain Markets In China, 1736-1842, Karl Ryavec, Mark Henderson, Rocco Bowman

Comparative Civilizations Review

No abstract provided.

Prevention And Reversal Of Elastin-Associated And Phosphate-Dependent Arterial Calcification Using Targeted Nanotherapeutics In Pre-Clinical Models, Fatema Tuj Zohora

All Dissertations

Vascular calcification can be life-threatening, involving calcium phosphate crystal deposits in the blood vessels. The calcification in the intimal layer of the arterial wall is usually associated with atherosclerotic plaque build-up that, in the advanced stage, harbors ‘dispersed’ and ‘spotty’ deposits of calcium phosphate crystals in the necrotic core of the plaque. In contrast, medial arterial calcification (MAC) can form independently of atherosclerosis and appears as ‘Railroad-like’ calcific deposits along degraded elastin lamellae in the medial layer of arteries. The mechanisms of such elastin-associated medial arterial calcification and potential therapies are the key concerns of this dissertation. MAC is common …

Glymphatic Transport Is Reduced In Rats With Spontaneous Pituitary Tumor, Lian Li, Guangliang Ding, Li Zhang, Hao Luo, Esmaeil Davoodi-Bojd, Qingjiang Li, Michael Chopp, Zhenggang Zhang, Quan Jiang

Neurology Articles

BACKGROUND AND OBJECTIVE: Pituitary tumor in patients induces adverse alterations in the brain, accompanied by cognitive deficits. Dysfunction of glymphatic waste clearance results in accumulation of neurotoxic products within the brain, leading to cognitive impairment. However, the status of glymphatic function in the brain with pituitary tumor is unknown. Using magnetic resonance imaging (MRI) and an advanced mathematical modeling, we investigated the changes of glymphatic transport in the rats carrying spontaneous pituitary tumor.

METHODS: Rats (22-24 months, female, Wistar) with and without pituitary tumor (n = 7/per group) underwent the identical experimental protocol. MRI measurements, including T2-weighted imaging and dynamic …

Protocol For A Randomized Controlled Trial On Community Education And Surveillance On Antibiotics Use Among Young Children In Nepal, Prajwol Nepal, Anup Subedee, Henish Shakya, Sanjaya Poudel, Supriya Joshi, Kshitij Karki, Deepak Bajracharya, Tyler Prentiss, Linda M. Kaljee, Yubraj Acharya

Global Health Initiative Articles

BACKGROUND: Antimicrobial resistance (AMR) is one of the top ten threats to global health. There exists limited empirical evidence on effective approaches to address this threat. In low- and middle-income countries (LMICs), one of the primary drivers of AMR is easy access to antibiotics without prescriptions, in particular from community pharmacies. Interventions to reduce non-prescribed use of antibiotics and surveillance systems to track such usage are critically needed. This protocol describes a study that aims to test the effect of an educational intervention targeted to parents of young children on non-prescribed antibiotics consumption in Nepal and to track such consumption …

Exploring The Effects Of Cannabidiol On Psychological Health, Cognitive Function, Neural Health, And Natural Killer Cells, Arjun Ramani

Dissertations

Cannabidiol (CBD), a non-psychotropic cannabis sativa derivative, is gaining attention as a potential promotor of neurological function and cognitive health and as a potential anti-inflammatory compound, although these claims lack evidence-based support from the scientific community. The purpose of this study was to determine whether 8 weeks of 2 doses, 40 mg (CB40) or 20 mg (CB20), of CBD containing beverages will improve psychological health, cognitive function, neural health as well as NK and NKT cell quantity and NK cell function when compared to a control vehicle beverage (CBDV) and a calorie-matched placebo beverage (PLAC) in a double-blind, randomized, placebo-controlled, …

Inkjet-Printed Electrochemical Sensors For Lead Detection, Annatoma Arif

Open Access Theses & Dissertations

This PhD dissertation research has developed a simple, miniaturized, sensitive, selective, reproducible, and disposable 3D (inkjet printed – additive manufacturing technology) gold (Au) plated electrochemical sensor (ECS) on shape memory polymer (SMP) for aqueous lead detection. This technology has shown promising performance in the application of electrochemical sensing (lead (II) detection) due to increased effective electrode surface area (7.25 mm^2 ± 0.15 mm^2) despite miniaturizing lateral surface area (4.19 mm^2). The design, fabrication processes, optimization including bismuth functionalization, evaluation, uncertainty analysis, and cost analysis of the novel SMP based inkjet printed Au plated sensor have been delineated in this manuscript …

Queerness, Affect Theory, And Cruel Optimism In "The Yellow Wall-Paper", Lauren Stengel, Lauren E. Stengel

Research Papers

The way in which the resolution of Charlotte Perkins Gilman’s “The Yellow Wall-paper” seems both enabling and disabling when it comes to the possibility of resistance to structures of power has been the subject of much criticism. Challenging Walter Benn Michael’s claim that “The Yellow Wall-paper” critiques only women’s exclusion from capitalist labor and not capitalist labor itself, I argue that while the narrator’s freedom/unfreedom at the end of the story attests to her own attachment to these structures, the story itself does not. Further I argue that Gilman, in fact, is working through her own cultural critique similar to …

Mountain Lion Resource Selection In The California Central Coast: Modeling Habitat Suitability For A Large Carnivore In A Rapidly Changing Environment, Megan Elizabeth O'Connor

Master's Theses

Land use conversion toward agriculture such as orchards and vineyards can have severe negative impacts on habitat and wildlife, particularly large carnivores, globally through habitat fragmentation and loss. The mountain lion (Puma concolor) population in the California Central Coast is thought to provide “stepping-stone” connectivity between several severely genetically compromised coastal populations throughout the Santa Cruz Mountains and several mountain ranges in Southern California; however, the California Central Coast is one of the fastest-developing regions of California with little protection against future land use conversion. Conserving areas of and corridors between high-quality mountain lion habitat through conservation easements …

Oikophilia: Relationships Among Life, Human Life, And Place In School Communities And Their Expressions In Curriculum, Mandi Leigh

Dissertations

This naturalistic, non-experimental inquiry explored relationships among life, human life, and place in school communities along with their expressions in school curriculum. I used educational criticism and connoisseurship to richly describe, interpret meaning, evaluate significance, and discern thematics surrounding relationships and how those relationships were expressed in the curriculum. Postmodern ecology provided the framework for acknowledging ecological precarity and performing the critical, as in essential, work of deconstructing what harms life that could be reconstituted as nourishment. The first study question was: What relationships exist among life, human life, and place in school communities? To answer the question, ecological data …

Fatty Acids And Parasitism: Towards A Better Understanding Of Lipid Metabolism In Trypanosoma Brucei, Joshua Saliutama

All Dissertations

Trypanosoma brucei is an extracellular eukaryotic parasite that causes sleeping sickness in humans and cattle. As an extracellular parasite, T. brucei relies on the host’s nutrients to satisfy its growth requirements. The parasite is unusual because it does not uptake most of the host’s lipid species. Instead, T. brucei prefers to perform de novo synthesis of most lipid species. One of the lipid species that T. brucei can both uptake and synthesize is fatty acids. In my thesis work, I investigated the dynamics of fatty acid uptake, metabolism, and utilization of T. brucei. My work starts by determining the …

The Functional Implications Of Anuran Metamorphosis For Survival, Locomotor Performance, And Limb Bone Mechanical Properties, Chase Kinsey

All Dissertations

Many organisms must contend with navigating their environments from birth. An organism could be classified as – and is often studied – in the context of locomotion through a single habitat type. However, many organisms must contend with a wide variety of environmental obstacles and substrates. What’s more, a large group of animals, Lissamphibia, do so while undergoing drastic transformation of their morphology and locomotor appendages. This transformation, term metamorphosis, typically coincides with a movement from water as a tadpole, to land as a frog or salamander. Many studies have associated this transitionary period with decreased locomotor performance and worse …