Digital Commons Network^™

Knowledge, Attitudes And Practices On Dietary Supplements Among Allied Health Sciences Undergraduates Of Sri Lanka, Pramoda Kalpani Wanniarachchi, Sayumi Amarasinghe, Shashini Nipunika De Silva, G.Shakila Meghashie, H. H. Vishwa Kumari Nisansala De Silva, S. B. Himali Priyadarshani

Journal of Innovation in Science, Engineering and Technology

According to research conducted in foreign coun-tries among undergraduates, there is a huge con-sumption of dietary supplements without proper consultation, and many have encountered adverse effects. However, there have been no satisfactory research studies done on dietary supplement usage among Allied Health Sciences undergraduates in Sri Lanka. The objective of the study was to de-scribe knowledge, attitudes, and practices of die-tary supplement usage among Allied Health Sci-ences undergraduates in Sri Lanka. In this descrip-tive cross-sectional study, a sample taken from a population of 2000 undergraduates of five Allied Health Sciences faculties in Sri Lanka were as-sessed using a structured, self-administered …

Gut Microbiome Can Increase Acquisition And Disease Risk For Hiv And Epstein-Barr Virus, Jeff Hansen

Browse All News

No abstract provided.

3d-Aware Multi-Class Image-To-Image Translation With Nerfs, Senmao Li, Joost Van De Weijer, Yaxing Wang, Fahad Shahbaz Khan, Meiqin Liu, Jian Yang

Computer Vision Faculty Publications

Recent advances in 3D-aware generative models (3D-aware GANs) combined with Neural Radiance Fields (NeRF) have achieved impressive results. However no prior works investigate 3D-aware GANs for 3D consistent multiclass image-to-image (3D-aware 121) translation. Naively using 2D-121 translation methods suffers from unrealistic shape/identity change. To perform 3D-aware multiclass 121 translation, we decouple this learning process into a multiclass 3D-aware GAN step and a 3D-aware 121 translation step. In the first step, we propose two novel techniques: a new conditional architecture and an effective training strategy. In the second step, based on the well-trained multiclass 3D-aware GAN architecture, that preserves view-consistency, we …

Novel Anti-Melanoma Compounds Are Efficacious In A375 Cell Line Xenograft Melanoma Model In Nude Mice, Sadeeshkumar Velayutham, Ryan Seerattan, Maab Khalid Sultan, Trisha Sea, Samaya Danthurthy, Baskaran Chinnappan, Jessica Landi, Kaitlyn Pearl, Aveta Singh, Keiran S. M. Smalley, Julia Zaias, Jun Yong Choi, Dmitriy Minond

HPD Articles

Despite the successes of immunotherapy, melanoma remains one of the deadliest cancers, therefore, the need for innovation remains high. We previously reported anti-melanoma compounds that work by downregulating spliceosomal proteins hnRNPH1 and H2. In a separate study, we reported that these compounds were non-toxic to Balb/C mice at 50 mg/kg suggesting their utility in in vivo studies. In the present study, we aimed to assess the efficacy of these compounds by testing them in A375 cell-line xenograft in nude athymic mice. Animals were randomized into four groups (n = 12/group): 10 mg/kg vemurafenib, and 25 mg/kg 2155-14 and 2155-18 thrice …

Focused Ultrasound-Mediated Brain Genome Editing., Yeh-Hsing Lao, Robin Ji, Joyce K Zhou, Kathy J. Snow, Nancy Kwon, Ethan Saville, Siyu He, Shradha Chauhan, Chun-Wei Chi, Malika S Datta, Hairong Zhang, Chai Hoon Quek, S Sarah Cai, Mingqiang Li, Yaned Gaitan, Lawrence Bechtel, Shih-Ying Wu, Cathleen Lutz, Raju Tomer, Stephen A Murray, Alejandro Chavez, Elisa E Konofagou, Kam W Leong

Faculty Research 2023

Gene editing in the brain has been challenging because of the restricted transport imposed by the blood-brain barrier (BBB). Current approaches mainly rely on local injection to bypass the BBB. However, such administration is highly invasive and not amenable to treating certain delicate regions of the brain. We demonstrate a safe and effective gene editing technique by using focused ultrasound (FUS) to transiently open the BBB for the transport of intravenously delivered CRISPR/Cas9 machinery to the brain.

Metapopulation Dynamics Of Sars-Cov-2 Transmission In A Small-Scale Amazonian Society, Thomas Kraft, Edmond Seabright, Sarah Alami, Samuel M. Jenness, Paul L. Hooper, Bret Beheim, Helen Davis, Daniel K. Cummings, Daniel Eid Rodriguez, Maguin Gutierrez Cayuba, Emily J. Miner, Xavier De Lamballerie, Lucia Inchauste, Stéphane Priet, Benjamin Trumble, Jonathan Stieglitz, Hillard Kaplan, Michael Gurven

ESI Publications

The severity of infectious disease outbreaks is governed by patterns of human contact, which vary by geography, social organization, mobility, access to technology and healthcare, economic development, and culture. Whereas globalized societies and urban centers exhibit characteristics that can heighten vulnerability to pandemics, small-scale subsistence societies occupying remote, rural areas may be buffered. Accordingly, voluntary collective isolation has been proposed as one strategy to mitigate the impacts of COVID-19 and other pandemics on small-scale Indigenous populations with minimal access to healthcare infrastructure. To assess the vulnerability of such populations and the viability of interventions such as voluntary collective isolation, we …

August 22, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

The Proteome Of Extracellular Vesicles Of The Lung Fluke Paragonimus Kellicotti Produced In Vitro And In The Lung Cyst, Lucia S Di Maggio, Kerstin Fischer, Devyn Yates, Kurt C Curtis, Bruce A Rosa, John Martin, Petra Erdmann-Gilmore, Robert S W Sprung, Makedonka Mitreva, R Reid Townsend, Gary J Weil, Peter U Fischer

2020-Current year OA Pubs

Paragonimiasis is a zoonotic, food-borne trematode infection that affects 21 million people globally. Trematodes interact with their hosts via extracellular vesicles (EV) that carry protein and RNA cargo. We analyzed EV in excretory-secretory products (ESP) released by Paragonimus kellicotti adult worms cultured in vitro (EV ESP) and EV isolated from lung cyst fluid (EV CFP) recovered from infected gerbils. The majority of EV were approximately 30-50 nm in diameter. We identified 548 P. kellicotti-derived proteins in EV ESP by mass spectrometry and 8 proteins in EV CFP of which 7 were also present in EV ESP. No parasite-derived proteins were …

Automated And Assisted Identification Of Stroke Using Feature-Based Brain Imaging, Karl A. Kasischke, William Scott Burgin

USF Patents

Provided herein are systems and methods for automated identification of volumes of interest in volumetric brain images using artificial intelligence (AI) enhanced imaging to diagnose and treat acute stroke. The methods can include receiving image data of a brain having header data and voxel values that represent an interruption in blood supply of the brain when imaged, extracting the header data from the image data, populating an array of cells with the voxel values, applying a segmenting analysis to the array to generate a segmented array, applying a morphological neighborhood analysis to the segmented array to generate a features relationship …

Nanoparticles For Treatment Of Posterior Segment Ocular Diseases And Conditions, Kathleen Emily-Ann Halasz, Yashwant V. Pathak, Vijaykumar Bhadabhai Sutariya

USF Patents

The present invention concerns nanoparticles useful for treating posterior segment ocular diseases or conditions, such as macular degeneration and diabetic retinopathy; compositions comprising the nanoparticles; methods for producing the nanoparticles; and methods for treating posterior segment ocular diseases or conditions, comprising administering the nanoparticles or compositions to the ocular posterior segment of an afflicted eye.

Utilization Of Wellness Practices For Burnout And Stress During Covid-19 Among An Interdisciplinary Cohort Of Emergency Healthcare Workers, Michael J. Zdradzinski, Sheri-Ann O. Kaltiso, Roslyn Seitz, Timothy P. Moran, Jennifer Clements, Sheryl L. Heron, Michelle D. Lall

Journal of Wellness

Introduction: The Coronavirus Disease (COVID-19) introduced additional stress to the baseline occupational stressors of emergency care workers. The objectives of this study were to evaluate perceived stress and burnout and the utilization and perceived benefit of wellness practices among emergency healthcare workers (EHCWs), including: emergency physicians, advanced practice providers (APPs), nurses, and departmental administrative staff during the COVID-19 pandemic.

Methods: A cross-sectional 28-item electronic survey of EHCWs at three hospitals in a major United States city was used to measure participants’ utilization and perceived benefit of wellness practices, burnout (2-item measure), overall stress (perceived stress scale), and stress …

About Premedical Programs At Ud, Udayton

Pre-Health Resource Center Campus Communications

No abstract provided.

Elements Of Creative Writing, Grant Tracey, Rachel Morgan, Jeremy Schraffenberger

Faculty Book Gallery

This free and open access textbook introduces new writers to some basic elements of the craft of creative writing. The authors—Rachel Morgan, Jeremy Schraffenberger, and Grant Tracey—are editors of the North American Review, the oldest and one of the most well-regarded literary magazines in the United States. We’ve selected nearly all of our readings and examples from writing that has appeared in our pages over the years. Because we had a hand in publishing these pieces originally, our perspective as editors permeates this book. As such, we hope that even seasoned writers might gain insight into the aesthetics of our …

Role Of Ripk3 In The Pathogenesis Of Tet2 Mutant Hematopoietic Malignancies, Kanak Joshi

Dissertations

Hematopoiesis is dynamically controlled by an epigenetic landscape that regulates gene transcription. Ten-eleven translocation 2 (TET2) is a Fe2+ and α-ketoglutarate (α-KG)-dependent dioxygenase that regulates the transcriptional status of genes associated with hematopoietic stem cell self-renewal and multiple stages of lineage commitment and differentiation. TET2 mutations are commonly detected in almost all types of hematopoietic malignancies, including myeloproliferative disorder, acute myeloid leukemia, and peripheral T-cell lymphomas. In most cases, TET2 is a founder mutation that occurred in hematopoietic stem/progenitor cells (HSPCs). The mutant HSCs undergo clonal expansion and evolution with the accumulation of additional mutations for malignant transformation. Microbial-stimulated inflammatory …

2007 Great Day Program, Suny Geneseo

GREAT Day Programs

SUNY Geneseo’s First Annual G.R.E.A.T. Day.

The Value Of Right Heart Catheterization: Case Series Showing Benefits In A Variety Of Diagnoses, Max Ruge, David Fischman, Indranee Rajapreyar, Yevgeniy Brailovsky

Division of Cardiology Faculty Papers

Although the right heart catheterization (RHC) was first introduced in 1945, its use in the quantitative hemodynamic assessment of patients has remained of questionable benefit. With recent advances in pharmacotherapies and mechanical support devices, RHC has been increasingly used to assess and help tailor the management of more complex patient scenarios. We present a case series in which the use of the RHC was helpful in making complex medical decisions.

Initial Experience With An Electron Flash Research Extension (Flex) For The Clinac System, Kyuhak Oh, Kyle J. Gallagher, Megan Hyun, Diane Schott, Sarah Wisnoskie, Yu Lei, Samuel Hendley, Jeffrey Wong, Shuo Wang, Brendan Graff, Christopher Jenkins, Frank Rutar, Md Ahmed, Joshua Mcneur, Jeffrey Taylor, Marty Schmidt, Lasitha Senadheera, Wendy Smith, Subodh M. Lele, Ran Dai, Dong Jianghu (James), Y Yan, Su-Min Zhou

Department of Physics and Astronomy: Faculty Publications

Purpose: Radiotherapy delivered at ultra-high-dose-rates (≥40 Gy/s), that is, FLASH, has the potential to effectively widen the therapeutic window and considerably improve the care of cancer patients. The underlying mechanism of the FLASH effect is not well understood, and commercial systems capable of delivering such dose rates are scarce. The purpose of this study was to perform the initial acceptance and commissioning tests of an electron FLASH research product for preclinical studies.

Methods: A linear accelerator (Clinac 23EX) was modified to include a nonclinical FLASH research extension (the Clinac-FLEX system) by Varian, a Siemens Healthineers company (Palo Alto, …

Biomass Smoke Inhalation Promotes Neuroinflammatory And Metabolomic Temporal Changes In The Hippocampus Of Female Mice, David Scieszka, Yan Jin, Shahani Noor, Ed Barr, Marcus Garcia, Jessica Begay, Guy Herbert, Russell P. Hunter, Kiran Bhaskar, Rahul Kumar, Rama Gullapalli, Alicia Bolt, Mark A. Mccormick, Barry Bleske, Haiwei Gu, Matthew J. Campen

Pathology Research and Scholarship

Smoke from wildland fires has been shown to produce neuroinflammation in preclinical models, characterized by neural infiltrations of neutrophils and monocytes, as well as altered neurovascular endothelial phenotypes. To address the longevity of such outcomes, the present study examined the temporal dynamics of neuroinflammation and metabolomics after inhalation exposures from biomass-derived smoke. 2-month-old female C57BL/6 J mice were exposed to wood smoke every other day for 2 weeks at an average exposure concentration of 0.5 mg/m

Exploring The Possibilities Of A Standardized Questionnaire For Assessing Residents’ Needs, Amy Harder, Diane Craig, Glenn Israel, Matt Benge, Olivia Caillouet

Journal of Extension

Creating a standardized needs assessment instrument and methodology that can be shared across the Extension system can lead to increased capacity to identify the needs of our clientele. The purpose of our study was to determine if a questionnaire originally created to assess needs in Utah could be used to identify priority areas for programming as perceived by the residents of Florida. Data were obtained from individuals who opted into survey panels administered by Qualtrics. Adapting the Utah questionnaire resulted in the identification of four priority areas and saved organizational resources by decreasing the time needed for instrument development.

Triple-Negative Breast Tumors Are Dependent On Mutant P53 For Growth And Survival, Denada Dibra, Sydney M Moyer, Adel K El-Naggar, Yuan Qi, Xiaoping Su

Faculty, Staff and Student Publications

The TP53 tumor suppressor gene is mutated early in the majority of patients with triple-negative breast cancer (TNBC). The most frequent TP53 alterations are missense mutations that contribute to tumor aggressiveness. We developed an autochthonous somatic K14-Cre driven TNBC mouse model with p53R172H and p53R245W mutations in which mutant p53 can be toggled on and off genetically while leaving the tumor microenvironment intact and wild-type for p53. These mice develop TNBCs with a median latency of 1 y. Deletion of mutant p53R172H or p53R245W in vivo in these tumors blunts their tumor growth and significantly extends survival of mice. Downstream …

Evangelical School Of Nursing Residence Handbook, 1975, Advocate Aurora Health

Historical Documents - Combined

Evangelical School of Nursing, Oak Lawn, IL: Handbook for students at the Evangelical School of Nursing living in the residence halls.

The Torch, Evangelical School Of Nursing Yearbook, 1960, Advocate Aurora Health

Historical Documents - Combined

Evangelical School of Nursing, Oak Lawn, IL: Evangelical School of Nursing Yearbook from 1960 called "The Torch".

Scale Model Experiments Of Toxic Gas Production From The Combustion Of Polymers When Applied With Different Droplet Sizes Of Water Mist, Nicharee Thinnakornsutubutr, Masayuki Mizuno, Kazunori Kuwana

Progress in Scale Modeling, an International Journal

This research experimentally investigated the combustion of polymeric materials with water mist application in an enclosure, with an emphasis on the production of toxic gases. Two different diameters, ~100 and ~260 μm, were tested. The experimental conditions were determined based on Froude similarity laws for low drop Reynolds number conditions. Droplets and polymers’ physical and chemical properties influence the burning/extinguishing behavior and toxic-gas evolution. In general, larger droplets can extinguish a fire in a shorter time, and toxic gas concentrations in a test chamber decreased more rapidly. However, the large droplets tended to cause the flame expansion phenomenon for thermoplastics …

Methods And Apparatuses For On-Head Detection Of A Head-Mounted Display

Defensive Publications Series

The present application describes a computer-implemented method including a step of detecting, via a first sensor positioned on a HMD, an indication of an angular distance between a temple arm and an inner surface of the HMD. The method may also include a step of detecting, via a second sensor positioned on the HMD, an indication of contact between the HMD and skin of a user. The method may further include a step of detecting, via a third sensor positioned on the HMD, an indication of any one or more of motion of the HMD or a position of the …

Skin Extracellular Matrix Breakdown Following Paclitaxel Therapy In Patients With Chemotherapy-Induced Peripheral Neuropathy., Nathan P Staff, Sybil C Hrstka, Surendra Dasari, Enrico Capobianco, Sandra Rieger

Faculty Research 2023

The chemotherapeutic agent paclitaxel causes peripheral neuropathy, a dose-limiting side effect, in up to 68% of cancer patients. In this study, we investigated the impact of paclitaxel therapy on the skin of breast cancer patients with chemotherapy-induced peripheral neuropathy (CIPN), building upon previous findings in zebrafish and rodents. Comprehensive assessments, including neurological examinations and quality of life questionnaires, were conducted, followed by intraepidermal nerve fiber (IENF) density evaluations using skin punch biopsies. Additionally, RNA sequencing, immunostaining for Matrix-Metalloproteinase 13 (MMP-13), and transmission electron microscopy provided insights into molecular and ultrastructural changes in this skin. The results showed no significant difference …

Pop Gugak And E-Sang: Negotiating Traditional And Pop Genre Categories In Expressions Of Identity, Jessica Ellis

Theses and Dissertations

Korean traditional music has a popularity problem among Korea's contemporary audiences; given the choice of what to listen to, few South Koreans choose to listen to gugak. To address and overcome this popularity problem, traditional Korean musicians are negotiating and reconstructing traditional Korean music by adopting, appropriating, and altering elements of Korean and international pop music. To this end, Gugak groups recently have been incorporating western musical practices and aesthetics in their performances in digital platforms (YouTube and reality television programs) and in concerts to contemporize the genre and develop a more positive relationship between Koreans and their national music. …

So You Want To Teach Abroad?: A Guide For Prospective English Language Teachers, Michelle Mcmurray

TESOL MA Projects

Teaching English abroad has been one of the most exciting and rewarding experiences of my life. There are so many benefits to teaching English abroad, such as the opportunity to travel around the world and engage with other cultures, learn new languages, and develop both personal and professional skills. I have been fortunate to teach in China, Kenya, Brazil, and the Dominican Republic. My teaching responsibilities varied greatly in each country, and while these experiences were incredibly positive overall, each brought its own set of unique challenges. I often felt underqualified or too inexperienced for my roles, found myself in …

A Multi-Aerial Vehicle Platform For Testing Collaborative Mobility Formation Controllers, Matthew Snellgrove

LSU Master's Theses

Multi-agent systems have potential applications in a multitude of fields due to their ability to perform complex tasks with a high degree of robustness. Decentralized systems are multi-agent systems where sensing, control, and communication responsibilities are distributed amongst the agents giving this scheme a particularly high potential for robustness, adaptability, and complexity; however, this comes with its own list of challenges. Formation control is a topic in multi-agent systems that aims to have the agents moving as a virtual rigid body through space. In the literature, there have been successful implementation of formation control algorithms on robot agents in both …

Utility Of Body And Otolith Morphometry To Discriminate Cryptic Juveniles Of Two Sympatric Red Snappers (Perciformes: Lutjanidae), Miwa Takahashi, Corey B. Wakefield, Stephen J. Newman, Kyle B. Hillcoat, Benjamin J. Saunders, Euan S. Harvey

Fisheries Research Articles

The sympatric red snappers, Lutjanus erythropterus and Lutjanus malabaricus, are highly valued by commercial and recreational fishers along the tropical northern coasts of Australia and throughout their distribution. Studies on the life history and ecology of these congeners are confounded by difficulties in distinguishing the cryptic juveniles of each species (i.e., < 200 mm total length). This study aimed to validate a robust and cost-effective method to discriminate these juveniles using body and/or otolith morphometric data in a multivariate analysis. Juvenile samples were collected from the northwest (n = 71) and northeast (n = 19) coasts of Australia, and species identification was confirmed using DNA barcoding. The most parsimonious multivariate models achieved accurate species prediction rates of 98.8%, which consisted of just three body variables (dorsal fin length, the distance from the snout to the anterior edge of the eye, and either jaw length or distance from the snout to the preoperculum). The high level of discrimination for these cryptic juveniles highlights the robustness of this morphometric approach. The slightly lower rate of discrimination using otolith morphology (84.9%) was associated with greater regional variation in L. malabaricus between the northwest and northeast coasts. Slight variations in otolith shape are typically used to determine stock structure, which highlights the potential need to collect samples over a broader area of a species geographic range when using an otolith morphometric discrimination model. The method outlined in this study could be applied to distinguish other cryptic congeneric fish species, including from archived otolith collections. Moreover, this method has the potential to be utilized in assessing species compositions using body measurements from in situ stereo-video.

Individual Capture History Affects Site Use And Defensive Behavior Of Foraging Eastern Copperheads At A Recreational Site, James Benjamin Stratton

Online Theses and Dissertations

To maximize energy available for foraging or reproduction, optimality theory suggests individuals allocate energy toward defensive behaviors equivalent to risk of predation. In this framework, repeat encounters with humans that do not reduce individual fitness could result in a decreased defensive response toward humans in subsequent encounters. I investigated the role individual experience played in shaping the defensive behaviors and frequency of site use of foraging of eastern copperheads (Agkistrodon contortrix) at Koomer Ridge Campground in the Daniel Boone National Forest, Kentucky. Since 2015 this site has been used for ongoing, annual mark-recapture studies of the foraging ecology of copperheads …