Digital Commons Network^™

Alternate Day Feeding As A Cost-Effective Strategy For Tank Culture Of The Pacific Shortfin Eel Anguilla Bicolor Pacifica, Frolan A. Aya, John Carlo L. Unida, Maria Rowena R. Romana-Eguia, Nerissa D. Salayo

The Philippine Agricultural Scientist

There is a growing interest in the aquaculture of tropical anguillid eels as an export commodity. However, studies on feeding strategies, and the present demand to reduce feed costs need to be addressed to ensure the economic viability of eel farming. In this study, the effects of daily (DF) and alternate day (ADF) feeding on growth, feed utilization, body composition, blood chemistry, liver and intestinal morphology, and economic viability in the Pacific shortfin eel Anguilla bicolor pacifica were examined. Each feeding group of 30 elvers (166.25 ± 16.23 g mean initial wt) were randomly stocked in triplicate 4 m^{3 …}

Ride-Sharing With Advanced Air Mobility, Shuting Yang, Jiazhen Zhou, Dengfeng Sun, Daniel Delaurentis

Center for Connected and Automated Transportation

No abstract provided.

Hla-Ii Alleles Influence Physical And Behavioral Responses To A Whey Allergen In A Transgenic Mouse Model Of Cow's Milk Allergy, Danielle L. Germundson, Suba Nookala, Nicholas A. Smith, Yassmine Warda, Kumi Nagamoto-Combs

Biomedical Sciences Faculty Publications

The symptoms of food allergies vary significantly between individuals, likely due to genetic determinants. In humans, allergy development is initiated by antigen-presenting cells via class II human leukocyte antigen (HLA-II). The HLA-II gene is highly polymorphic, and its allelic variance is thought to influence the susceptibility of individuals to a particular allergen. However, whether antigen presentation by different HLA-II variants contributes to symptom variation is not clear. We hypothesized that HLA-II allelic variance affects symptom phenotypes, including immediate physical reactions and delayed behavioral changes, in individuals with food hypersensitivity. To test our hypothesis, male and female mice of three transgenic …

Sex-Dependent Effects Of Intestinal Microbiome Manipulation In A Mouse Model Of Alzheimer’S Disease, Harpreet Kaur, Suba Nookala, Surjeet Singh, Santhosh Mukundan, Kumi Nagamoto-Combs, Colin K. Combs

Biomedical Sciences Faculty Publications

Mechanisms linking intestinal bacteria and neurodegenerative diseases such as Alzheimer’s disease (AD) are still unclear. We hypothesized that intestinal dysbiosis might potentiate AD, and manipulating the microbiome to promote intestinal eubiosis and immune homeostasis may improve AD-related brain changes. This study assessed sex differences in the effects of oral probiotic, antibiotics, and synbiotic treatments in the AppNL-G-F mouse model of AD. The fecal microbiome demonstrated significant correlations between bacterial genera in AppNL-G-F mice and Aβ plaque load, gliosis, and memory performance. Female and not male AppNL-G-F mice fed probiotic but not synbiotic exhibited a decrease in Aβ plaques, microgliosis, brain …

Hla-Ii-Dependent Neuroimmune Changes In Group A Streptococcal Necrotizing Fasciitis, Ganesh Ambigapathy, Santhosh Mukundan, Kumi Nagamoto-Combs, Colin Combs, Suba Nookala

Biomedical Sciences Faculty Publications

Streptococcus pyogenes (Group A Streptococcus, GAS) bacteria cause a spectrum of human diseases ranging from self-limiting pharyngitis and mild, uncomplicated skin infections (impetigo, erysipelas, and cellulitis) to highly morbid and rapidly invasive, life-threatening infections such as streptococcal toxic shock syndrome and necrotizing fasciitis (NF). HLA class II allelic polymorphisms are linked with differential outcomes and severity of GAS infections. The dysregulated immune response and peripheral cytokine storm elicited due to invasive GAS infections increase the risk for toxic shock and multiple organ failure in genetically susceptible individuals. We hypothesized that, while the host immune mediators regulate the immune responses against …

Fine-Grained In-Context Permission Classification For Android Apps Using Control-Flow Graph Embedding, Vikas Kumar Malviya, Naing Tun Yan, Chee Wei Leow, Ailys Xynyn Tee, Lwin Khin Shar, Lingxiao Jiang

Research Collection School Of Computing and Information Systems

Android is the most popular operating system for mobile devices nowadays. Permissions are a very important part of Android security architecture. Apps frequently need the users’ permission, but many of them only ask for it once—when the user uses the app for the first time—and then they keep and abuse the given permissions. Longing to enhance Android permission security and users’ private data protection is the driving factor behind our approach to explore fine-grained contextsensitive permission usage analysis and thereby identify misuses in Android apps. In this work, we propose an approach for classifying the fine-grained permission uses for each …

Renin-Angiotensin-System Blockers And Igg Antibodies In End-Stage Renal Disease Hemodialysis-Receiving Patients Diagnosed With Covid-19 Infection, Sultan A. Almdallaleh, Abdulkareem O. Alsuwaida, Abdulhadi M. Altalhi, Dina M. Aljayar, Elzibair E. Massad, Mazaher M. Hamid, Parameaswari P. Jaganathan, Fadel H. Al-Hababi

Saudi Medical Journal

Objectives: To evaluate the prevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections among patients receiving in-center hemodialysis (ICHD), the relationship between the IgG antibody levels against the virus and SARS-CoV-2-associated symptoms, hemodialysis adequacy, and the antihypertensives used in order to control blood pressure. Methods: A prospective observational study was carried out at a tertiary care center, King Fahad Kidney Center, Riyadh, Kingdom of Saudi Arabia, between November 2020 and January 2021. A total of 214 ICHD patients with end-stage renal disease (ESRD) were included, and the levels of their anti-SARS-CoV-2 IgG antibodies were assessed after obtaining their informed consent. …

Variable Light Penetration And Chlorophyll Concentrations From A Vertical Profiler In The Gulf Of Maine, With Implications For Remote Sensing And Ecosystem Modeling, Terence W. O'Brien

Master's Theses and Capstones

Variability in light field penetration into the ocean alters both radiant heat flux and oceanic primary production. Both are increasingly important in the context of quantifying biologically-mediated atmospheric carbon fluxes and sea surface temperature increase in a changing climate. Accurate determination of light penetration into the upper ocean depends upon accurate estimates of the depth-resolved water absorption and attenuation properties through the water column, properties that are often assumed homogeneous vertically and slowly variant in time. This thesis explores all-new Gulf of Maine datasets collected using a moored vertical profiler that provides sub-hourly light attenuation profiles with sub-m vertical resolution …

Generation Of Lexa Enhancer-Trap Lines In Drosophila By An International Scholastic Network, Cory J. Evans, Ella S. Kim, Arjun Rajan, Kathleen Chang, Sanath Govindarajan, Clara Gulick, Eva English, Bianca Rodriguez, Orion Bloomfield, Stella Nakada, Charlotte Beard, Sarah O’Connor, Sophia Mastroianni, Emma Downey, Matthew Feigenbaum, Caitlin Tolentino, Abigail Pace, Marina Khan, Soyoun Moon, Jordan Diprima, Amber Syed, Flora Lin, Yasmina Abukhadra, Isabella Bacon, John Beckerle, Sophia Cho, Nana Esi Donkor, Lucy Garberg, Ava Harrington, Mai Hoang, Nosa Lawani, Ayush Noori, Euwie Park

Biology Faculty Works

Conditional gene regulation in Drosophila through binary expression systems like the LexA-LexAop system provides a superb tool for investigating gene and tissue function. To increase the availability of defined LexA enhancer trap insertions, we present molecular, genetic, and tissue expression studies of 301 novel Stan-X LexA enhancer traps derived from mobilization of the index SX4 line. This includes insertions into distinct loci on the X, II, and III chromosomes that were not previously associated with enhancer traps or targeted LexA constructs, an insertion into ptc, and seventeen insertions into natural transposons. A subset of enhancer traps was expressed in …

Rural Business Development Corporation Annual Report 2023, Department Of Primary Industries And Regional Development, Western Australia

All other publications

In accordance with section 63 of the Financial Management Act 2006, we hereby submit for your information and presentation to Parliament, the annual report of the Rural Business Development Corporation for the reporting period ended 30 June 2023.

The annual report has been prepared in accordance with the provisions of the Financial Management Act 2006 and the Rural Business Development Corporation Act 2000.

Acromegaly: Pathophysiological Considerations And Treatment Options Including The Evolving Role Of Oral Somatostatin Analogs, Charles P. Daniel, Maxwell J. Wagner, Grant E. Borne, Connor J. Plaisance, Shahab Ahmadzadeh, Alfonso Aquino, Sahar Shekoohi, Adam M. Kaye, Elyse M. Cornett, Alan D. Kaye

Pacific Faculty Work

Acromegaly is a condition most commonly diagnosed in the fifth decade of life and has numerous treatment options. In this regard, Mycapssa^® is the first FDA-approved oral octreotide capsule for treating acromegaly, combining the efficacy of the somatostatin receptor ligand, octreotide, with the ease of a twice-daily oral capsule. Where surgical treatment is not an option, somatostatin analogs, including octreotide, are the first line of medical treatment for acromegaly, requiring regular subcutaneous or intramuscular injections administered by a patient’s healthcare provider. Octreotide capsules (Mycapssa^®) provide an alternative to these somatostatin receptor ligand injections by combining octreotide with …

Electing Prosecutors Based On Their Convictions, Ryan Edwards

Nevada Law Journal

Prosecutors wield broad influence over criminal cases due to their power of prosecutorial discretion. In recent years, a growing number of prosecutors are exercising that discretion by crafting policies that deprioritize or decline prosecution of entire categories of crimes. Because most state and local jurisdictions in the United States elect their head prosecutor, policy-based prosecutorial discretion can even become an electoral strategy for voters who seek to express displeasure with certain categories of criminal laws.

Following the reversal of Roe v. Wade in 2022, criminalized abortion has become one such category of law in many states. The 2022 midterm elections …

Agricultural Pesticide Regulatory Environment For Pollinator Protection Across Geographical Regions, Ngoc T. Phan, Edwin G. Rajotte, Guy Smagghe, Zong-Xin Ren, David J. Biddinger, Neelendra K. Joshi

Entomology and Plant Pathology Faculty Publications and Presentations

The alarming decline of pollinator populations has raised significant concerns worldwide and prompted the need for effective pesticide risk assessment within the Integrated Pest and Pollinator Management (IPPM) framework. This paper examines the diverse approaches to pollinator protection within the pesticide regulatory environments of the United States (US), the European Union (EU), and selected Asian countries. The US adopts a reactive approach, regulating pesticides only after evidence of harm emerges, while the EU embraces a proactive stance under the precautionary principle. The EU has implemented stringent regulations, including neonicotinoid bans, and conducts coordinated research on pesticide impacts. In contrast, some …

Strawberry Production Guide For The Northeast, Midwest, And Eastern Canada 2nd Edition, Rebecca Sideman, Kaitlyn Orde

UNH Cooperative Extension

This guide is intended as a comprehensive resource for both novice and experienced strawberry growers in northeastern North America. It provides information on all aspects of strawberry culture. The second edition has been updated and revised throughout, and includes expanded and new information on variety selection (Ch. 3), production systems (Ch. 4), harvesting, handling and transportation (Ch. 12), marketing (Ch. 13) and budgeting/economics (Ch. 14). In addition, a new section on diagnosing problems in strawberry plantings has been added (Ch. 15).

A Lamprey Neural Cell Type Atlas Illuminates The Origins Of The Vertebrate Brain, Francesco Lamanna, Francisca Hervas-Sotomayor, A. Phillip Oel, David Jandzik, Daniel Sobrido-Cameán, Gabriel N. Santos-Durán, Megan L. Martik, Jan Stundl, Stephen A. Green, Thoomke Brüning, Katharina Mößinger, Julia Schmidt, Celine Schneider, Mari Sepp, Florent Murat, Jeramiah J. Smith, Marianne E. Bronner, María Celina Rodicio, Antón Barreiro-Iglesias, Daniel M. Medeiros, Detlev Arendt, Henrik Kaessmann

Markey Cancer Center Faculty Publications

The vertebrate brain emerged more than ~500 million years ago in common evolutionary ancestors. To systematically trace its cellular and molecular origins, we established a spatially resolved cell type atlas of the entire brain of the sea lamprey—a jawless species whose phylogenetic position affords the reconstruction of ancestral vertebrate traits—based on extensive single-cell RNA-seq and in situ sequencing data. Comparisons of this atlas to neural data from the mouse and other jawed vertebrates unveiled various shared features that enabled the reconstruction of cell types, tissue structures and gene expression programs of the ancestral vertebrate brain. However, our analyses also revealed …

Bacteroides Fragilis In The Gut Microbiomes Of Alzheimer’S Disease Activates Microglia And Triggers Pathogenesis In Neuronal C/Ebpβ Transgenic Mice, Yiyuan Xia, Yifan Xiao, Zi-Hao Wang, Ashfaqul M. Alam, John P. Haran, Beth A. Mccormick, Xiji Shu, Xiaochuan Wang, Keqiang Ye

Markey Cancer Center Faculty Publications

Gut dysbiosis contributes to Alzheimer’s disease (AD) pathogenesis, and Bacteroides strains are selectively elevated in AD gut microbiota. However, it remains unknown which Bacteroides species and how their metabolites trigger AD pathologies. Here we show that Bacteroides fragilis and their metabolites 12-hydroxy-heptadecatrienoic acid (12-HHTrE) and Prostaglandin E2 (PGE2) activate microglia and induce AD pathogenesis in neuronal C/EBPβ transgenic mice. Recolonization of antibiotics cocktail-pretreated Thy1-C/EBPβ transgenic mice with AD patient fecal samples elicits AD pathologies, associated with C/EBPβ/Asparaginyl endopeptidase (AEP) pathway upregulation, microglia activation, and cognitive disorders compared to mice receiving healthy donors’ fecal microbiota transplantation (FMT). Microbial 16S rRNA sequencing …

Donald Trump’S Contribution To The Study Of Politics And The Life Sciences, John Hibbing

Department of Political Science: Faculty Publications

If the life sciences are to have much to say about politics, there needs to be a universal element to political orientations. In this essay, I argue that the recent prominence of nativist, law-and-order, populist politicians reveals the nature of this universal element. All social units have to address bedrock dilemmas about how to deal with norm violators and how welcoming to be to outsiders as well as to proponents of new lifestyles. Might differences on these core dilemmas be the universal element of political life? Using the followers of one of the most prominent examples of a nativist political …

Clostridioides (Clostridium) Difficile: A Silent Nosocomial Pathogen, Ibrahim A. Al-Zahrani

Saudi Medical Journal

Clostridioides difficile (C. difficile) infection is still a threat to many healthcare settings worldwide. Clostridioides difficile epidemiology has changed over the last 20 years, largely due to the emergence of hypervirulent and antimicrobial-resistant C. difficile strains. The excessive use of antimicrobials, the absence of optimal antibiotic policies, and suboptimal infection control practices have fueled the development of this pressing health issue. The prudent use of antimicrobials, particularly broad-spectrum agents, and simple infection control measures, such as hand hygiene, can significantly reduce C. difficile infection rates. Moreover, the early detection of these infections and understanding their epidemiological behavior using accurate laboratory …

Factors Affecting California Grassland Biodiversity: Two Case Studies, Nora Bales

Master's Theses

Biodiversity loss over the last century has been significant and is projected to increase. Biodiversity loss is accelerating due to climate change and habitat loss and degradation. Biodiversity supports key ecosystem services including pollination services, climate regulation, and water filtration. Biodiversity conservation is a top priority for land managers and researchers, however many ecological studies with practical applications lack a thorough understanding of the soil environment in their study system. We conducted two case studies integrating soil and plant data to answer management questions. The first case study investigated the relationship between a threatened plant, Hooveria purpurea var. purpurea and …

Investigation Of Common Milkweed As A Novel Food Crop For New England, Colter Allen Flynn

Master's Theses and Capstones

Neglected and underutilized crop species (NUCS) represent a reservoir of biodiversity that can be leveraged to help develop a more robust and sustainable food production system. This investigation sought to identify an edible crop species with potential as a novel food crop for the New England food system and conduct a subsequent evaluation of the chosen species based on agronomic traits of interest. A series of interviews were conducted between August and December 2020 with regional experts and specialists with experience in the subject matter. Based on interview data and a subsequent literature review, Asclepias syriaca (common milkweed) emerged as …

Effects Of Perennial Forage Composition And Harvest Intensity On The Weed Seedbank Community, Lilly E. Hartman

Master's Theses and Capstones

Most arable weeds arise from a resident soil seedbank and are typically controlled with tillage and herbicides, each of which pose sustainability challenges to growers and consumers. However, agronomic management practices that reduce weed seed input to the seedbank and that accelerate mortality of seeds already in the soil could reduce the need for more conventional weed control. Previous research and farmer practice has demonstrated that rotation of annual crops with several years of perennial forage can reduce weed abundance and the need for chemical weed control. In perennial forage systems, crop species and harvest intensity may have important effects …

The Under-Appreciated Roles Of Spatial Scale, Individual Variation, And Nonlinearity In Spatial Ecology, David Heit

Master's Theses and Capstones

Spatial ecology is a central component of ecological inquiry. In an ever-changing world facing threats including climate change, human sprawl, and novel zoonotic diseases, understanding how animals use space and make habitat decisions can be invaluable to research, management, and conservation of animal species. The techniques and technology used in spatial ecology have advanced continuously over time to provide increasingly detailed data and analyses and mitigate potential statistical biases. However, there remain many potential biases that warrant further attention in the discipline of spatial ecology. This is especially true for conceptual biases, or biases inherent to the ways in which …

Evaluation Of A Wave Powered Water Pump Performance By Ocean Field Testing And Wec-Sim Modeling, Chelsea Kimball

Master's Theses and Capstones

A rising demand for macroalgae (or seaweed) has led researchers to seek out methods of increasing macroalgae aquaculture yields. Macroalgae is a food product, and may be used in biofuel, animal feed, and fertilizer. Applying upwelling technology to macroalgae aquaculture has been shown to increase biomass yield. A wave-powered upwelling device (or water pump) generates cold, nutrient-rich water flow to the surface of an aquaculture operation. A wave pump device developed at University of New Hampshire was refurbished and outfitted with instrumentation to determine its performance. Testing in the laboratory on both the device and instrumentation was conducted to prepare …

Mass Loading Model Of Per- And Polyfluoroalkyl Substances To New Hampshire's Great Bay With A Focus On Surface Waters, Gage Moran

Master's Theses and Capstones

Per- and polyfluoroalkyl substances (PFAS) have been used in manufacturing as textile stains, soil repellants, grease proof products, food product coatings, aqueous film forming foams, and more for over 50 years. The carbon-fluorine chain of these compounds is chemically and thermally stable, resistant to biodegradation, and has both hydrophobic and lipophobic properties, making its chemistry unique for many commercial and industrial uses. This research work gathered existing concentration information from New Hampshire’s Environmental Monitoring Database on PFAS in the watershed and discharging to the Great Bay to better frame monitoring locations, temporal trends, and data gaps in the watershed. A …

Movement Patterns, Habitat Use, And Survival Of Anadromous Rainbow Smelt In Great Bay Estuary, Nh, Chloe Pearson

Master's Theses and Capstones

Anadromous rainbow smelt in the northeastern USA have experienced range contraction over the past few decades, and are now restricted to waters in Massachusetts and northwards. In their current range, populations appear to be in decline, including in New Hampshire; in Great Bay, New Hampshire, conservation methods such as habitat restoration and stocking efforts have been suggested to improve populations, with projects underway to implement these methods. To optimize these conservation efforts, specific knowledge regarding rainbow smelt habitat use in estuaries is needed, including the specific habitats used as well as timing and duration of use. In March 2021, we …

Spatially Revealing The Liver’S Genetics In The Dehydration Resistant Cactus Mouse, Sean Pierre-Louis

Master's Theses and Capstones

This study is motivated by the global issue of climate change and its impact on the increasing prevalence of hot and arid environments, which in turn leads to water scarcity. While acknowledging these challenges, our research focuses on understanding the how desert-dwelling cactus mouse, P. eremicus, have adapt to their native desert environment. Using spatial transcriptomic sequencing, we created a spatial atlas of gene expression in hepatocytes and examined the baseline expression patterns in different zones. In this spatial atlas, hepatocyte genes were sequenced from their original spatial location in the tissue to establish the zonal patterns with neighboring hepatocytes. …

Determining Cardinal Temperatures For Eight Cover Crop Species, Mila V. Pessotto, Trenton Roberts, Matthew B. Bertucci, Caio Dos Santos, Jeremy Ross, Mary C. Savin

Horticulture Faculty Publications and Presentations

Growing degree days (GDD) is a tool to predict plant growth and can be adapted for use in any plant species, including cover crops. A limitation of the GDD calculation is accurate temperature parameters used to predict plant development. For most cover crop species, the cardinal temperatures are not well defined in the literature, leading to a less accurate calculation of GDD. The objective of this study was to determine the cardinal temperatures of eight cover crop species, including Austrian winter pea (Pisum sativum), balansa clover (Trifolium michelianum), barley (Hordeum vulgare), black-seeded oats ( …

What Is It Like To Be A Brain Organoid? Phenomenal Consciousness In A Biological Neural Network, Ivanna Montoya, Daniel Montoya

College of Humanities and Social Sciences

It has been shown that three-dimensional self-assembled multicellular structures derived from human pluripotent stem cells show electrical activity similar to EEG. More recently, neurons were successfully embedded in digital game worlds. The biologically inspired neural network (BNN), expressing human cortical cells, was able to show internal modification and learn the task at hand (predicting the trajectory of a digital ball while moving a digital paddle). In other words, the system allowed to read motor information and write sensory data into cell cultures. In this article, we discuss Neural Correlates of Consciousness (NCC) theories, and their capacity to predict or even …

The Effect Of Nutrients And Their Role In The Progression Of Periodontal Disease, Sara Ali, M. Ali, Abdulnasser Al-Gebori, Hassanien Al-Jumaily, Poh Ooi, Asalnov Nuraddin

Journal of Applied Sciences and Nanotechnology

Periodontal disease is a common disease and may affect 90% of people and is classified into gingivitis and periodontitis. The objective of this study was if the deficiency of some vitamins and trace elements affects the increase in exposure to periodontal diseases or to find out whether the periodontal disease can cause changes in the blood level of some nutrients and their role in reducing periodontal diseases. For this purpose, samples were collected from the University of Baghdad, College of Dentistry, Department of Periodontics, Periodontics Clinic, including a group of 40 patients with periodontitis and another 40 patients with gingivitis …

Fors 333.01: Fire Ecology, Philp Higuera

University of Montana Course Syllabi, 2021-2025

No abstract provided.