Digital Commons Network^™

Estradiol’S Role In Timely Puberty Onset In The Ewe, Eliana Gerardine Aerts

Graduate Theses, Dissertations, and Problem Reports (ETD)

In female sheep, the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus triggers luteinizing hormone (LH) to be released from the pituitary. Luteinizing hormone, in turn, acts on the ovaries to elicit estradiol (E₂) release. E₂ acts in a negative feedback manner to control the amount of LH released. The increase in LH release that drives puberty onset results from a decrease in sensitivity to E₂ as the animal ages. However, the neural mechanisms mediating this change in sensitivity are not known, as is where in the hypothalamus E₂-negative feedback occurs. In the arcuate …

Transparent And Conductive Gallium Oxide Electrode For Simultaneous Recording And Optogenetic Stimulation, Christopher Patrick Carey

Graduate Theses, Dissertations, and Problem Reports (ETD)

Neural electrode technology has been around for centuries since the times of Galvani. In early electrophysiology experiments metal wires were used to induce contractions in dissected animals. The metal wire electrode has since been a standard tool to both stimulate and record neural activity. In the past two decades, a new strategy for neural stimulation has been formulated based on the emergent field of optogenetics. Optogenetics refers to the use of light-sensitive proteins genetically imbedded in the membrane of a neuron to elicit neural activity. This technique offers more selectivity in the stimulation of neurons. Typical optogenetic neural electrodes, or …

Comparison Between Coronally Advanced Flap With Sub-Epithelial Connective Tissue Graft And Tunnel Technique With Sub-Epithelial Connective Tissue Graft In Achieving Mean Root Coverage At Multiple Recession Defects: A Retrospective Study, Christian Daniel Davila

Graduate Theses, Dissertations, and Problem Reports (ETD)

Aim: The primary objective is to retrospectively compare the mean root coverage (MRC) achieved using a coronally advanced flap and sub-epithelial connective tissue graft (CAF + CTG) with that achieved using the tunnelling technique and sub-epithelial connective tissue graft (TUN + CTG) for the treatment of multiple recession defects. The secondary objectives are to compare the proportion of complete root coverage (CRC) achieved with CAF + CTG compared to TUN + CTG, compare the proportion of CRC achieved in these two techniques with respect to level of training (American board-certified periodontist or Graduate periodontics residents) and to evaluate the …

Women In Extension Persevering In Leadership Roles, Lexis Danielle Trickett

Graduate Theses, Dissertations, and Problem Reports (ETD)

Over the last several decades, the rates at which women have been pursuing higher levels of education have steadily increased. However, there is a discrepancy between the number of women graduating, and the amount entering the workforce, specifically in leadership roles. The purpose of this study was to share a current profile of women in the West Virginia Cooperative Extension Service by allowing them to describe their career journeys, supports and barriers they may or may not have faced, and mentoring experiences. By using a non-experimental quantitative methodology, a population of male and female Extension Agents and Specialists were surveyed …

Characterization And Evaluation Of Various Biochar Types As Green Adsorbents For Rare Earth Element Recovery From Aqueous Solutions, Oluwaseun Victor Famobuwa

Graduate Theses, Dissertations, and Problem Reports (ETD)

Rare earth elements (REEs) are members of the lanthanide family (atomic number 57 – 71). They are significantly important to the global economy due to their applications in renewable energy, defense, and medical industries. REEs are primarily derived from bastnaesite and monazite but may also be present in xenotime, cerite, alanite, and many other types of mineralization in lesser amounts. Due to the increasing demand for REEs and their criticality in the supply chain, the need to explore secondary sources of REEs has gained tremendous importance.

Secondary sources of REEs include but are not limited to acid mine drainage (AMD), …

Characterization Of Host Cell Specific Interactions During Spotted Fever Group Rickettsiae Infection, Emerson Towey

Graduate Theses, Dissertations, and Problem Reports (ETD)

Vector-borne diseases have been increasing over the past few years due to changes in climate and disturbances in the vectors’ natural environment. To mitigate the risks of these diseases, it is necessary to understand pathogen biology and how it interacts with a host to cause disease. Here we focus our attention on the tick-borne pathogen, Rickettsia rickettsii. R. rickettsii is a member of the spotted fever group (SFG) Rickettsiae and is the etiological agent of Rocky Mountain spotted fever (RMSF), a fatal human disease that is lacking an effective vaccine. Members of the bacterial genus Rickettsia are obligate intracellular endoparasites …

A Podcasting Series On The Historical Event Of Hawk’S Nest Tunnel Disaster, Hannah G. Morgan

Graduate Theses, Dissertations, and Problem Reports (ETD)

This professional project will look into the Hawk’s Nest Tunnel Disaster – a disaster that was birthed due to extreme capitalism and exploitation during the 1930s. This project will explore historical documents, books and interviews with those who are passionate about the event. With that research material, I will produce an educational narrative podcast with a cohesive storyline detailing the event, including a beginning, middle and end. The podcast series will be uploaded to Apple Podcasts and Spotify. This professional project can be replicated and used for other similar projects.

4d Epr Oximetry Imaging For 4d Bioprinting And Tissue Engineering, Sajad Sarvari

Graduate Theses, Dissertations, and Problem Reports (ETD)

Bioprinting, akin to 3D printing, employs cell-laden hydrogels such as GelMA (Gelatine Methacrylate) and Alginate instead of plastic or resin to create biological structures. The printing process followed by subsequent tissue maturation is known as 4D bioprinting, where the fourth dimension is time. Ensuring adequate and consistent oxygen, O2, supply within 3D bioprint volume over the entire maturation period process is crucial, as even transient hypoxia can impact cellular behavior and phenotypes. However, printing of fully developed vasculature remains an unresolved technical challenge. Several approaches to chemically (peroxides) or biologically (photosynthesis) generate oxygen during bioprint maturation have been proposed. However, …

An Evaluation Of A Human-Operant Effort Manipulation And Effects Of Effort Disparity On Renewal, Haleh Amanieh

Graduate Theses, Dissertations, and Problem Reports (ETD)

The relative effort of target and alternative responses during treatments using differential reinforcement of alternative behavior may impact the likelihood that a previously reduced target response will reemerge following a context change (i.e., “renewal”). The purpose of this study was to evaluate the role of an effort disparity between target and alternative responses in a human-operant arrangement. Eighteen college students clicked on one (Experiment 1) or two (Experiment 2) circles moving on a computer screen for points. In Experiment 1, the speed of the circle was manipulated as an index of effort such that three circle speeds (i.e., 50, 100, …

Assessing The Effectiveness Of Crime Scene Measuring Techniques, Lauren M. Fagan

Graduate Theses, Dissertations, and Problem Reports (ETD)

Crime scene mapping is the process of measuring and fixing items present in the crime scene to obtain a detailed to-scale map of the scene as found by the crime scene investigators. When bloodstain patterns are present, investigators must analyze the bloodstains to assist in determining where the blood-shedding event occurred. The volume of origin is determined through a manual stringing method that is labor-intensive and destructive.

Technological advancements have been made in other fields, such as land surveying, and were adopted by law enforcement-related fields. These advancements include electronic terrestrial scanners, like the total station, and three-dimensional scanners, like …

Have You Been To Orlando?: In Relation To The Regulation Of Self-Preferencing In Antitrust Law, Eunkwang Ha

South Carolina Journal of International Law and Business

As a mother of two and a South Korean professional studying abroad in the United States, one of my top priorities for our family's time here was to visit Orlando. My children had endured quite a bit of disruption as I pursued my professional goals, and I felt visiting Disney World and Universal Studios would be a bit of recompense. Although I wanted to use a package deal from a Korean travel agency, it was not a good choice because I needed to stay at hotels connected to Disney World and Universal Studios.

Due to the self-preferencing of Disney World …

Baker's Novelty Plays, Script, Boston, Massachusetts, 1894

Documents

Baker's Novelty Plays script for "The District School at Blueberry Corners, A Farcical Entertainment in Three Scenes" by Laura M. Parsons, 22 pages, Walter H. Baker Company, Boston, Massachusetts, 1894. Signed by Walter H. Baker.

St. James Theatre, Playbill, New York, New York, 1937

Documents

St. James Theatre, playbill for "King Richard II." by William Shakespeare, starring Maurice Evans and Ian Keith, staged by Margaret Webster, New York, New York, beginning 1937 March 8.

Theatre Memphis, Program, Memphis, Tennessee, 1989

Documents

Theatre Memphis, program for "Big River, The Adventure of Huckleberry Finn," music and lyrics by Roger Miller, book by William Hauptman, directed by Sherwood Lohrey, Memphis, Tennessee, 70th Anniversary Mainstage Season, 1989 September 7-24.

Magazine Article, "Beale Street Sings The Blues No More," From The Downtowner, Memphis, Tn, November 1993

Documents

Magazine article, "Beale Street Sings The Blues No More," by Paul Gerald, The Downtowner, Memphis, TN, Vol. 3, Issue 10, November 1993.

Controlled Substance Monitoring Database; 2024 Report To The 113th Tennessee General Assembly, Tennessee. Department Of Health.

Controlled Substance Monitoring Database Annual Report

No abstract provided.

In Pursuit Of Equity Under Nepa: Apalachicola’S Invisibility In The Tristate Water Wars, Abigail E. Andre

University of Memphis Law Review

In the presence of significant environmental impacts, the National Environmental Policy Act (“NEPA”) requires agencies to take a hard look at community effects. However, analysis of human impacts under NEPA is generally cursory. While executive orders requiring consideration of environmental justice have raised awareness of community impacts in some instances, agency approach is inconsistent, and courts largely view such analysis as a box to be checked. Such cursory consideration of human impacts leaves historically underserved communities in a legal blind spot that perpetuates environmental and procedural inequity. Using the U.S. Army Corps of Engineers’ management of the Apalachicola, Chattahoochee, and …

Rural Health Care In The Age Of Hospital Bankruptcies, Sonal Rastogi

Emory Bankruptcy Developments Journal

In recent years, the United States has witnessed a surge in bankruptcy filings within the healthcare sector. Inflation, rising expenses, shifts in payment models, labor shortages, legislative uncertainty, and mounting pharmaceutical costs have impacted all healthcare organizations, casting a shadow over communities. This is particularly evident in rural America where hospital closures have shrunk access to healthcare services. This Comment delves into the challenges and interests at play when healthcare entities and nonprofit organizations navigate bankruptcy proceedings, paying particular attention to the challenges faced by health care business bankruptcy proceedings.

This Comment argues that the current bankruptcy framework requires adjustments …

What A Waste: Nitrogen Runoff And Rates In The Maumee River (Ohio, Usa), Ryanne Antonette Cimatu

Browse all Theses and Dissertations

Excess anthropogenic nitrogen (N), primarily from agricultural field fertilization, causes nutrient runoff that stimulates harmful algal blooms (HABs) in western Lake Erie. As a critical tributary to Lake Erie, nutrient loading from the Maumee River drives the intensity of the annual summer HABs in the western basin. Knowledge gaps around rates of N transformations in the Maumee River currently hinder the calibration of in-river parameters in Soil and Water Assessment Tool (SWAT) models for the Maumee watershed. To address these gaps, this research quantified rates of ammonium uptake, ammonium remineralization, nitrification, and bacterial respiration alongside physicochemical parameters of the river. …

Biomechanical Simulation Of Cardiovascular Implantable Electronic Device Leads With Residual Properties, Anmar Mahdi Salih

Browse all Theses and Dissertations

Implantable leads used in pacemakers, defibrillators, and cardiac resynchronization therapy are designed for in-vivo applications, yet their longevity is inevitably shaped by the conditions within the human body. The mechanical behavior of these leads can be affected over time, necessitating the evaluation of their residual properties. Two main insulators, silicone, and polyurethane are commonly used for the outer insulation of cardiac leads. Understanding the long-term performance of these insulators is crucial for ensuring the reliability and safety of cardiac implantable devices. The research aims to assess the long-term mechanical properties and performance of implantable leads utilized in cardiovascular implantable electronic …

The Relationship Between Aim Pathways Professional Development, Teachers’ Sense Of Efficacy For Literacy Instruction, And Literacy Knowledge, Among K-3 Teachers, Shakita Bagwell

Electronic Theses and Dissertations

Teaching reading has been an ongoing challenge for many educators across the United States. Numerous studies suggest that teachers feel they were not adequately prepared to teach reading and have low efficacy in delivering literacy instruction. Teaching reading requires educators to be knowledgeable about the alphabetic principle, decoding new words, and how the brain learns to read. This exploratory study aimed to investigate the relationship between AIM Pathways Professional Development on teachers’ literacy efficacy and knowledge compared to teachers who did not receive the professional development. A survey was administered to eighty-eight teachers in Mississippi Literacy Support Schools. Multidimensional scaling …

More Than A Feeling: Materializing Sympathy In Nineteenth-Century American Literature, Kathleen Downes

Electronic Theses and Dissertations

“More than a Feeling: Materializing Sympathy in Nineteenth-Century American Literature” breaks from a long tradition of criticism that only considers the nineteenth-century belief that sympathy was a benevolent, voluntary, imaginative act of feeling that maintains moral rectitude through the identification of suffering with others. In this context, sympathy is primarily defined as identificatory sympathy. “More than a Feeling” expands the definition of sympathy in the nineteenth century as also something that could be atmospherically communicated, transmitting good or bad feeling, and thus affecting and infecting those around them. This other form of sympathy, which for this project I term “effluvial …

Mississippi's America: Late Southern Writing On National Themes, Jacob Fennell

Electronic Theses and Dissertations

This project examines three texts each from three Mississippi authors working today: Kiese Laymon, Jesmyn Ward, and Mary Miller. These authors’ literary constructions of their home state and the South as a whole serve as critical, political frames for the United States. As a result, their work is well-served by the questions and methodology of New Southern Studies, a field actively invested in conceptions of the U.S. South as nonexceptional and lodged within greater geopolitical contexts. Indeed, the original call for New Southern Studies from Houston A. Baker, Jr. and Dana Nelson speaks to a problem of a false national …

Running In The Rain: Stories, Vinh Hoang

Electronic Theses and Dissertations

A short story collection.

As Lightning, Lenna Mendoza

Electronic Theses and Dissertations

A collection of poems.

Montesquieu: The Nature Of L’Esprit Des Lois, Christian Jax Murray

Electronic Theses and Dissertations

When Baron de Montesquieu received a copy of his L’Esprit des lois, he was horrified by the total removal and reorganization of critical parts of his text, changed ideas, and an abnormal amount of printing errors in his work. While he saw these issues hindering the reception of his work, this thesis argues that the chaos of the text, in both its style and publication, made the book more popular instead of hindering it. Montesquieu, his editor, and his publisher constructed a new kind of text that was broad in its subject matter and ambiguous in its meaning where its …

Stabilized Fingolimod Nanoemulsion Ophthalmic Formulation For The Treatment Of Retinal Degeneration, Mekhala Sharad Naik

Electronic Theses and Dissertations

Fingolimod (FTY) is a sphingosine-1-phosphate receptor agonist and an inhibitor of ceramide synthase, reducing cellular ceramide levels and mitigating photoreceptor degeneration. The current research focuses on enhancing the stability of a previously reported FTY nanoemulsion (FTY-NE) topical (eyedrop) ophthalmic formulation. However, FTY undergoes oxidative and base mediated hydrolytic degradation, and the previously reported formulation, although effective, failed within 90 days storage at room temperature. This study explores various approaches, such as addition of buffer, cosolvents, steric stabilizer, viscosity enhancer, emulsifying agent, and a chelating agent in the NE system to increase shelf-life. The FTY-NE formulations (0.3% drug load) were prepared …

Moderation In Online Incel Forums: A Comparison Of Warning Behaviors, Katherine Elizabeth Norris

Electronic Theses and Dissertations

Incels constitute an online community characterized by shared negative perspectives concerning masculinity, women, and societal norms. Platforms such as Twitter and Reddit have implemented content moderation measures aimed at curtailing the dissemination of incels' ideologies, which often promote violence and suicidal ideation. To observe the influence of content moderation on incel discourse, this study examined posts from two distinct incel forums: one subject to moderation and another without such restrictions. Employing thematic analysis, common themes within the posts were identified, and the occurrence of negative language was quantitatively assessed. Findings revealed that the moderated forum exhibited a higher prevalence of …

Investigation Of Evolution In Fungal Traits At Multiple Genetic Scales, Brooke Allen

Electronic Theses and Dissertations

The study of fungal traits is critical for understanding community assembly and ecosystem function, as traits related to resource acquisition, enemy avoidance, and stress tolerance link fungi to their ecological roles. Symbiotic relationships, such as those between ectomycorrhizal (EcM) fungi and their host plants, greatly influence fungal traits and play a key role in fungal evolution. In this study, we addressed the evolution of EcM fungal traits, particularly biosynthetic gene clusters (BGCs), at multiple genetic scales, including individual genes, genotypes within populations, and a broader phylogenetic perspective across the fungal kingdom. First, we surveyed the diversity of BGCs in native …

Molecular Modeling Of Inhibitors Of Severe Acute Respiratory Syndrome Coronavirus 2 And Urinary Tract Infections, Priyanka Samanta

Electronic Theses and Dissertations

Infectious diseases are the leading cause of disability-adjusted life years worldwide. Glycans initiate host–pathogen interactions in two particular infectious diseases, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and urinary tract infections (UTIs). In this work, recent advances of computational tools in drug design are utilized to target these glycanspecific host–pathogen interactions for the potential prevention of SARS-CoV-2 or UTIs.

SARS-CoV-2 viral entry into the host cell is mediated by the viral S-protein. Carbohydrate molecules bind to the receptor-binding domain (RBD) of the S-protein which interacts with angiotensin-converting enzyme 2 and leads to host cell invasion. Here we report computational studies …