Digital Commons Network^™

Del Arquetipo Al Tropo: Guía Para La Creación De Intereses Románticos En Dating Simulators (2024), Álvaro Espinosa Barrero

Grado en Diseño y Desarrollo de videojuegos

En la última década, los simuladores de citas (dating simulators) han experimentado un crecimiento significativo en popularidad dentro de la industria de los videojuegos. Estos juegos, que combinan elementos de simulación y romance, permiten a los jugadores interactuar con personajes virtuales y desarrollar relaciones románticas a través de elecciones narrativas y estratégicas. El objetivo principal de este trabajo es analizar el diseño narrativo de los personajes romanceables en estos simuladores, con un enfoque particular en el juego "Monster Prom".

El diseño de personajes en los dating simulators es un aspecto crucial que influye en la inmersión y satisfacción del jugador. …

Deathstack. Análisis, Diseño Y Creación De Animaciones De Combate A Tiempo Real Para Un Videojuego 3d Estilizado De Fantasía Con Vista Top Down (2024), Juan Pedro Muñoz Herreruela

Grado en Diseño y Desarrollo de videojuegos

Con motivo del desarrollo de DeathStack, un videojuego roguelite con estilo 3D estilizado y vista top-down con mecánicas de construcción de mazos y combate a tiempo real, en el que cada carta representa una habilidad diferente durante el combate, se ha decidido realizar una investigación para saber cómo representar visualmente de forma correcta las animaciones de combate a tiempo real en este tipo de juegos. Para lograrlo, se ha hecho un estudio comparativo de 3 juegos importantes actualmente en la industria de este estilo: Hades, League of Legends y Pokémon Unite.

Siempre apoyados sobre la base de los 12 principios …

Impacto De Las Limitaciones Técnicas En La Creación Y Evolución De Personajes Icónicos En Videojuegos Clásicos (2024), Héctor Muñoz Martín

Grado en Diseño y Desarrollo de videojuegos

La investigación se centra en la evolución de los personajes icónicos de videojuegos como Samus Aran, Pikachu y Cloud Strife, y cómo han sido representados a lo largo del tiempo con el avance de la tecnología.

El objetivo principal es observar cómo las limitaciones tecnológicas iniciales fomentaron la creatividad en el diseño de personajes y cómo los desarrolladores han adaptado estos diseños en nuevas entregas, manteniendo su relevancia y atractivo entre distintas generaciones de jugadores.

La investigación emplea un análisis comparativo de los diseños de personajes en diferentes eras de videojuegos, examinando aspectos como la paleta de colores, el uso …

Historia E Importancia Del Impacto De La Feminidad En El Videojuego (2024), María Teresa Rendón Caballero

Grado en Diseño y Desarrollo de videojuegos

Este trabajo busca recopilar, investigar y valorar la influencia de la feminidad en el videojuego.

Para ello, el documento explora históricamente los juegos dirigidos al público femenino en las últimas cinco décadas, y su impacto en la sociedad; se examinan casos clave y momentos significativos, y además, se analizan las tendencias a futuro de la representación de la feminidad (que no necesariamente de la mujer), cuestionando su necesidad en la sociedad actual.

Se emplea una metodología de análisis histórico y proyección de tendencias, con las que luego se realizará un estudio cualitativo, basado en las entrevistas a profesionales del sector.

Shadow Lord. Emoción Y Empatía En Videojuegos: El Impacto De Las Animaciones Faciales En Las Cinemáticas (2024), Alejandro Rosa Moreno

Grado en Diseño y Desarrollo de videojuegos

En esta investigación se ha estudiado la importancia de las animaciones faciales dentro de las cinemáticas de los videojuegos y cómo pueden afectar al jugador. También se ha investigado los mejores casos de títulos populares como God of War, The Last of Us 2 y Hellblade 2.

Por otro lado se buscó las empresas conocidas dentro de España, donde se captura el movimiento tanto de la cara como del cuerpo en un espacio especializado para grabar animaciones. De igual modo con aplicaciones que capturan el movimiento de la cara desde el móvil. También se ha comparado la diferencia entre la …

Entre Colores Y Siluetas: Psicología De La Composición En Los Key Art De Videojuegos (2024), Carlota De La Prida Cogollos

Grado en Diseño y Desarrollo de videojuegos

This investigation seeks to understand how to create efficient Key Arts in terms of narrative by focusing on various patterns in composition and their emotional effect. It will also cover the psychology behind colors and the cultural associations made to them. The lighting in a scene and the importance of characters and their body language will also be relevant in this analysis. We will accomplish this by studying different compositions in some games' Key Arts both visually and psychologically. The results will conclude the importance of these elements when it comes to creating an emotional bond with the target and …

Desarrollo De Un Sistema Avanzado De Checkpoints, Para Mejorar La Precisión De La Posición En Los Circuitos De Los Videojuegos De Carreras (2024), Vicente Brisa Saez

Grado en Diseño y Desarrollo de videojuegos

Numerosos videojuegos de carreras emplean colliders o zonas de contacto, que funcionan como checkpoints o puntos de control. Estos checkpoints desempeñan un papel crucial en la determinación de la posición del jugador en la carrera. Cuando un jugador atraviesa un checkpoint, el sistema registra este avance y actualiza su posición en el marcador de la carrera, además se utilizan técnicas sofisticadas para calcular la distancia del jugador al collider, lo que permite una actualización de la posición en tiempo real. ¿Desde qué punto exacto se mide la distancia para garantizar una precisión óptima en la determinación de la posición del …

Stenotrophomonas Riyadhensis Sp. Nov., Isolated From A Hospital Floor Swab, Guerrino Macori, Ahmed Ali Al-Qahtani, Leonard Koolman, Sahar Althawadi, Maysoon Mutabaqani, Rustom Bashtawi, Sulaiman Aljumaa, Reem Saad Almaghrabi, Séamus Fanning

Articles

During the analysis of a collection of Pseudomonas strains linked to an outbreak in an intensive care unit at King Faisal Specialist Hospital and Research Center in 2019, one isolate (CFS3442T) was identified phenotypically as Pseudomonas aeruginosa. However, whole-genome sequencing revealed its true identity as a member of the genus Stenotrophomonas, distinct from both P. aeruginosa and Stenotrophomonas maltophilia. The isolate demonstrated: (i) a significant phylogenetic distance from P. aeruginosa; (ii) considerable genomic differences from several S. maltophilia reference strains and other Stenotrophomonas species; and (iii) unique phenotypic characteristics. Based on the combined geno- and phenotypic data, we propose that …

Generation, Characterisation And Identification Of Bioactive Peptides From Mesopelagic Fish Protein Hydrolysates Using In Silico And In Vitro Approaches, Maria Hayes, Azza Naik, Leticia Mora, Bruno Iñarra, Jone Ibarruri, Carlos Bald, Thibault Cariou, David Reid, Michael Gallagher, Ragnhild Dragøy, Jorge Galino, Alba Deyà, Sissel Albrektsen, Lars Thoresen, Runar G. Solstad

Articles

This study generated bioactive hydrolysates using the enzyme Alcalase and autolysis from mesopelagic fish, including Maurolicus muelleri and Benthosema glaciale. Generated hydrolysates were investigated for their bioactivities using in vitro bioassays, and bioactive peptides were identified using mass spectrometry in active hydrolysates with cyclooxygenase, dipeptidyl peptidase IV and antioxidant activities. In silico analysis was employed to rank identified peptide sequences in terms of overall bioactivity using programmes including Peptide Ranker, PrepAIP, Umami-MRNN and AntiDMPpred. Seven peptides predicted to have anti-inflammatory, anti-type 2 diabetes or Umami potential using in silico strategies were chemically synthesised, and their anti-inflammatory activities were confirmed using …

Pharmacokinetic Modeling Of Metonitazene And Isotonitazene Using In Vitro And In Vivo Models And Comparison To Human Postmortem Casework, Justine P. Sorrentino

Theses and Dissertations

Metonitazene and isotonitazene are two benzimidazole opioids that are contributing to the opioid crisis nationwide. Limited pharmacokinetic data has been published on these nitazene compounds, therefore this study sought to determine if these two structurally similar opioids would have comparable half-lives and clearance utilizing in vitro and in vivo models. Using the data determined in the pharmacokinetic study, and by testing human postmortem cases, this study aimed to inform interpretation of these drugs detected in human casework. Sample analysis for all aspects of the study was performed utilizing LC/MS/MS. In vitro pharmacokinetics of both drugs were examined using a human …

Streptozotocin-Induced Diabetes Increases Kidney Toxicity In Rats Exposed To Ochratoxin A, Belkys Gonzalez

Theses and Dissertations

Due to the rising occurrence of diabetes in the population and the prevalence of OTA exposure via ingestion of contaminated foodstuffs, there is a need to assess the possible renal interaction of a diabetic disease state in concurrence with OTA exposure. Sprague Dawley rats were treated with streptozotocin to induce experimental diabetes and then orally exposed to 0.5 mg/kg body weight OTA once a day for 21 days. Renal biomarkers and light microscopy were evaluated to assess the interaction between diabetic nephropathy and OTA exposure. LLC-PK1 proximal tubule cells were used as an in vitro model to assess the potential …

Exposure To Dithiocarbamate Fungicide Ziram Results In Hepatic And Renal Toxicity In Long-Evan Rats, Jeffrey Chen

Theses and Dissertations

Ziram is a broad spectrum fungicide that is used on a variety of crops. It has been shown to display a wide array of toxicological effects, however, there is still a scarcity of mechanistic data regarding how it facilitates those effects. One of its presumed mechanisms of toxicity is due to the production of oxidative stress. However, whether the production of oxidative stress is due to its dimethyldithiocarbamate backbone, its metal moiety, or a combination of both, is still unknown. Contributing to the production of oxidative stress is ziram’s ability to alter essential metal homeostasis through transchelation of other essential …

Defining Scribbles: How Do Early Childhood Teachers Perceive Scribbles As A Part Of Emergent Literacy?, Sandy Dellalonga

Theses and Dissertations

The purpose of this qualitative, phenomenological study was to understand early childhood teachers’ perceptions surrounding the topic of childhood scribbles as they relate to emergent literacy. Sociocultural theory provided a foundation for this research because of its focus on relationships between children, other children, and teachers to foster learning experiences (Gee, 2011; Vygotsky, 1978, 1998). Additionally, social semiotic theory also guided this research because childhood scribbles represent children’s “signs” which can also influence communication and literacy skills (Kress, 1997). The participants were nine preschool, transitional kindergarten, kindergarten, and first grade teachers (N=9) who volunteered to complete an open-ended survey, follow-up …

Comparison Of Professional Impressions Of Hikikomori Across Cultures: A Secondary Data Analysis, Marko Lamela

Theses and Dissertations

This study examined the impressions of two hikikomori vignettes by professionals across different countries to determine possible similarities or differences across countries. Originally viewed as a cultural disorder, hikikomori has been observed in different countries. This study used an existing data set of a 2010 study to review diagnostic impressions using the ICD-10 and DSM-IV-TR coding systems, as well as a free response. Additionally, this study reviewed professional impressions on the best treatment for hikikomori. This study reviewed these responses based on country of origin and cultural type. A correlation was found between ICD-10 and DSM-IV-TR diagnosis, country, and cultural …

Identity Denial And Food Choice: Do Chinese Americans Reassert Their American Identity Through Food?, Shelagh Mahbubani

Theses and Dissertations

Food choice is impacted by a variety of different factors, including cultural, social and socioeconomic (Chen & Antonelli, 2020; Contento, 2008; Rozin, 2015). Food choice has a major impact on an individual’s health, and research has shown an association between the prototypical “American diet” and an increased risk for health conditions such as hypertension, diabetes, and stroke (Liu et al., 2020). One important social factor that can influence food choice is the desire to appear as a prototypical member of a social group (Cruwys et al., 2012). For example, when an individual’s social identity is questioned (identity threat), they may …

Is The Juridical Field Of Environmental Law In India Gendered? A Study Of Environmental Justice In Goa Through An Ecofeminist Lens, Shweta Dilip Singh Sinha

Theses and Dissertations

The aim of this study is to examine whether the “juridical field,” as defined by Bourdieu, of environmental law in India (Goa), is gendered. As per Bourdieu, the legal field is neither as neutral nor as autonomous as the legal profession asserts it is. It relies heavily on the juridical practices of universalization, appropriation, and naming or categorization in order to constantly reimagine and negotiate its own boundaries. This study examines these juridical practices including acts of symbolic violence committed in the process of ‘naming’ or ‘defining’ within legal terms extra-legal concepts, mainly environmental toponyms, such as, ‘“forest,” “CRZ” (Coastal …

What Motivates Authors To Include Religious Identity In Children's Picture Books?, Kenneth J. Eiker

Theses and Dissertations

This dissertation explores children's authors' experiences of and motivations for including religious and spiritual themes in their picture books. It investigates the intricate connection between authors' backgrounds, including their cultural, spiritual, or religious, and familial roots, and how these elements permeate their writing. The study examines these authors' lived experiences and personal narratives, uncovering how their unique identities shape the portrayal of complex spiritual or religious themes in children's literature. Across the interviews, several themes were identified, including family teachings, religious upbringing, and personal spirituality. Authors draw from a wealth of personal experiences, such as Matt de la Peña's Christian …

Evaluation Of Microglia’S Structural Variations Within An Organotypic Hippocampal Slice Model After Regionalized Toxic Injury, Jesus Antonio Trejos

Theses and Dissertations

The dendritic cells of the CNS, the microglia (MG), are an initiation point of the immunological response within the post blood-brain barrier (BBB) compartment. Microglia morphology drastically changes in response to cell stress to a much different non-dendritic morphology. This investigation postulates that if the first MG responses to toxic injury are isolated and studied in greater morphological detail there is much to be learned about MG metamorphosis from a baseline (M2) to an activated (M1) state. The organotypic hippocampal slice was the experimental setting used to investigate microglial response to toxic injury. This isolates dendritic cellular responses and associated …

Insulin And Dma Suppress The Innate Immune Response Against Aav, Tianxiang Qi

Theses and Dissertations

Adeno-Associated Virus (AAV) is extensively utilized in various clinical trials and approved gene therapies. Despite its widespread use, the immune response to AAV vectors remains a significant limitation. Extensive research has been conducted to mitigate adaptive immune challenges, such as pre-existing antibodies and inhibiting the adaptive immune response. This study, however, centers on the innate immune response elicited by AAV, exploring the modulatory effects of insulin and DMA. Initially, we examined the impact of DMA and insulin on the human liver cell line Hep3B and the human macrophage cell line U937 by culturing together in transwell inserts. Following stimulation with …

Interplay Between Rna Editing And Alternative Splicing Modulates Biophysical And Pharmacological Properties Of The Ion Channel Cav1.3, Willy Munyao

Theses and Dissertations

Alternative splicing and adenosine-to-inosine (A-to-I) RNA editing are post-transcriptional mechanisms that promote proteomic diversity in the brain. The impact of RNA editing on brain physiology is underscored by its association with the etiology and pathogenesis of various neurological and neurodegenerative diseases. Alternative splicing of exon 43 within the CaV1.3 C-terminus produces long (CaV1.3L) and short (CaV1.343S) variants exhibiting distinct gating and pharmacological properties. While the physiological role of CaV1.3 A-to-I RNA editing in brain function is still unfolding, recent findings indicate that unedited CaV1.3 channels display larger calcium influx and enhanced neuronal excitability, suggesting that A-to-I RNA editing may act …

Mobocertinib Antagonizes Multidrug Resistance In Abcb1- And Abcg2-Overexpressing Cancer Cells, Xingduo Dong

Theses and Dissertations

The resistance of cancer cells to multiple drugs, known as multidrug resistance (MDR), remains a significant obstacle that leads to the ineffectiveness of cancer chemotherapy. The overexpression of ATP-binding cassette (ABC) transporters, particularly ABCB1 and ABCG2, has been strongly correlated with MDR. There is an urgent need to explore and identify novel inhibitors targeting ABCB1 and ABCG2 to overcome the related MDR. Mobocertinib (TAK-788) is an orally administered, irreversible EGFR/HER2 inhibitor approved for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) exon 20 insertion mutations. This study …

The Condor, Dominique Bussell

Celebrating Writers and Writing in our Communities

No abstract provided.

Song Of A Starving Mother, Shayla Frandsen

Inscape

“Please eat,” my husband will beg me. “Can I make you a sandwich?” I wish it were as simple as a sandwich. Nobody wishes more than me. I look at him and say, “I can’t.” I say, “Not right now.”

A Backpack In The River, Shamae Budd

Inscape

That morning, we awoke to the silence of snow—the first snowfall that winter, like white gauze, an inch thick on the cars and lawn and pavement, exhilaratingly blank after the red and yellow color-chaos of autumn. I looked out the window and pulled my winter boots from the closet, tugging my husband to join me for a walk before breakfast. Two months married, we bundled ourselves into knitted hats and scarves and gloves and made our way to the river trail, listening to the muffled sound of our feet leaving prints in the snow.

Creeping Things, Shamae Budd

Inscape

I lay in bed a few weeks ago, admiring the flatness of my stomach, grieving in advance the lack-of-flatness I can expect when my husband and I decide to start growing children of our own, and I found myself wondering, strangely, how snakes are born. Do they hatch from eggs, or are they born live and wriggling?

God Is A Poet, Matthew Wickman

Inscape

Why do we need literature? Certainly, there is much to admire in thoughtful, beautifully crafted narratives, poems, and plays, in gripping stories, layered characters, and poignant turns of phrase. But need is more intense than admiration, more desperate than mere affection. A graduate school friend and Church member once remarked to me, astutely, that if one surveys all the world’s civilizations over the course of known history, one can find plenty of examples of societies that had no concept of private property or insurance industries or professional sports teams or universities or lawyers or finance capitalists or plastic surgeons (and …

Undergraduate Catalog Of Studies, 2023-2024, University Of Arkansas, Fayetteville

Undergraduate Catalog of Studies

No abstract provided.

Logos-Sophia, Elliott Norman, Donald Wayne Viney, Keith Elliott Perkins, Addyson Kay Campbell, Hunter Hinds, Scott Squires

LOGOS-SOPHIA: The Journal of the PSU Philosophical Society

Logos-Sophia, Volume 17, Spring 2024. The Journal of the Pittsburg State University Philosophical Society has largely been a student publication with occasional faculty contribution

Stealing, Scavenging, Or Storing? Breeding Behaviors Of Unisexual Ambystoma Salamanders, Jane Venezia

Master's Theses and Doctoral Dissertations

The unisexual Ambystoma salamander complex is a lineage of all-female salamanders that use a unique form of reproduction: kleptogenesis. Kleptogenesis requires sperm from male salamanders of co-occurring sexual species, potentially putting unisexual and sexual females in breeding competition. We investigated if unisexual salamanders require courtship from sexual males or if they can use sperm left over from previous breeding events. We put unisexual salamanders into boxes containing spermatophores from a previous courtship and examined if they laid viable eggs. We also genotyped adults and embryos to assess parentage. Some of the unisexuals in the boxes produced viable eggs; however, the …

Increasing The Efficacy Of Actinomycin D With Resveratrol In Aerodigestive Tract Cancers, Lukmon Morenikeji Raji

Theses, Dissertations and Capstones

Chemotherapy poses a significant challenge for cancer patients due to drug-associated toxicity, which often results from their effects on both healthy (normal) and cancerous cells. While various options aim to reduce toxicity and optimize beneficial effects, a comprehensive solution remains elusive. Cyclotherapy is one such approach developed to protect normal cells from the toxic effects of chemotherapy drugs. The basic principle underlying cyclotherapy is p53- dependent cell cycle arrest of normal cells while killing cancer cells via a p53-independent mechanism using a second drug. In our research, we investigated the inhibitory effects of a combination of two low-dose anticancer drugs, …