Digital Commons Network^™

Full Issue, Volume 36, Issue 1

Landas

No abstract provided.

A Constellation Approach To Understanding Extremist White Supremacy, Kathleen Blee, Robert Futrell, Pete Simi

Sociology Faculty Articles and Research

Reflecting on long-term intensive ethnographic fieldwork, we sketch a “constellation” framework for understanding U.S. extremist white supremacy. Rather than tracing fluctuating people and organizations to explain the persistence of white supremacist extremism, we suggest that focusing on a core set of practices, ideas, and emotions offers a more complex, nuanced, and useful interpretation. We contrast our constellation framework with more typical “bucket” approaches that tend to compartmentalize a complex reality into categories that do not sufficiently match extremism’s dynamism.

Mir126-Targeted-Nanoparticles Combined With Pi3k/Akt Inhibitor As A New Strategy To Overcome Melanoma Resistance, Maria Beatrice Arasi, Gabriele De Luca, Laura Chronopoulou, Francesca Pedini, Eleonora Petrucci, Michela Flego, Annarita Stringaro, Marisa Colone, Luca Pasquini, Massimo Spada, Valentina Lulli, Maria Chiara Perrotta, George Adrian Calin, Cleofe Palocci, Mauro Biffoni, Federica Felicetti, Nadia Felli

Faculty, Staff and Student Publications

Metastatic melanoma poses significant challenges as a highly lethal disease. Despite the success of molecular targeting using BRAFV600E inhibitors (BRAFis) and immunotherapy, the emergence of early recurrence remains an issue and there is the need for novel therapeutic approaches. This study aimed at creating a targeted delivery system for the oncosuppressor microRNA 126 (miR126) and testing its effectiveness in combination with a phosphatidylinositol 3-kinase (PI3K)/ protein kinase B (AKT) inhibitor for treating metastatic melanoma resistant to BRAFis. To achieve this, we synthesized chitosan nanoparticles containing a chemically modified miR126 sequence. These nanoparticles were further functionalized with an antibody specific to …

Infant Growth And Body Composition From Birth To 24 Months: Are Infants Developing The Same?, Shane A. Norris, Lukhanyo H. Nyati, Alexia Murphy Alford, Nishani Lucas, Ina S. Santos, Caroline S. Costa, Rebecca Kuriyan, V Pujitha Wickranasinghe, Shabina Ariff, Andrew P. Hills

Department of Paediatrics and Child Health

Background: Given the importance of infancy for establishing growth trajectories, with later-life health consequences, we investigated longitudinal body composition among infants from six economically and ethnically diverse countries.
Methods: We recruited mother-infant dyads using the WHO Multicenter Growth Reference Study criteria. We measured fat-free mass (FFM) in 1393 (49% female) infants from birth to 6 months of age (Australia, India, and South Africa; n = 468), 3-24 months of age (Brazil, Pakistan, South Africa, and Sri Lanka; n = 925), and derived fat mass (FM), fat mass index (FMI), and fat-free mass index (FFMI). Height-for-age (HAZ), weight-for-age (WAZ), and weight-for-length …

Experimental Research On Contests, Subhashish M. Chowdhury, Dan Kovenock, Anwesha Mukherjee

ESI Working Papers

Contests are situations in which agents compete by irreversibly expending costly resources in an attempt to win a prize. Due to their applications in conflict, rent-seeking, organizational incentives, sports, litigation, and political campaigns, contests are widely applied in the social sciences. In this survey we summarize some main results and recent developments of experimental studies in contest theory. We also point out their broader applications in the social sciences.

Surveillance And Selective Treatment Of Brugia Malayi Filariasis Eleven Years After Stopping Mass Drug Administration In Belitung District, Indonesia, Taniawati Supali, Yenny Djuardi, Santoso, Lita Renata Sianipar, Nungki Hapsari Suryaningtyas, Rahmat Alfian, Yossi Destani, Elisa Iskandar, Hendri Astuty, Noviani Sugianto, Peter U Fischer

2020-Current year OA Pubs

A key component to achieving the global goal of elimination of lymphatic filariasis (LF) is the availability of appropriate tools for disease mapping, monitoring, and surveillance. However, the development of these tools for a neglected disease such as LF can be a challenge. The lack of a commercial market and low familiarity with these diseases leave little incentive for diagnostic manufacturers to invest in this space. The Filarial Test Strip (FTS) development story provides a case study on how a multi-stakeholder, public-private partnership model facilitated the development, evaluation, and introduction of a new monitoring and surveillance tool for LF. This …

Pathways To Care For Psychosis In Rural Uganda: Mixed-Methods Study Of Individuals With Psychosis, Family Members, And Local Leaders, Yang Jae Lee, Sophie Waimon, Et Al.

2020-Current year OA Pubs

BACKGROUND: Low- and middle-income countries (LMICs) bear a disproportionate burden of mental illness, with limited access to biomedical care. This study examined pathways to care for psychosis in rural Uganda, exploring factors influencing treatment choices.

METHODS: We conducted a mixed-methods study in Buyende District, Uganda, involving 67 in-depth interviews and 4 focus group discussions (data collection continued until thematic saturation was reached) with individuals with psychotic disorders, family members, and local leaders. Structured questionnaires were administered to 41 individuals with psychotic disorders.

RESULTS: Three main themes emerged: (1) Positive attitudes towards biomedical providers, (2) Barriers to accessing biomedical care (3) …

“You Have Become To Me A Deceitful Brook” – Jeremiah’S Challenges To God, Georg Fischer

Andrews University Seminary Studies (AUSS)

Jeremiah’s reproaches against God are exceptional in Old Testament prophecy. No other prophetic speaker dares to confront God so harshly and so often. The main passages considered in this article are Jer 4:10; 12:1–6; 15:15–18; 20:7–10; and 32:24–25. Jeremiah’s accusations cover a wide range of motifs: deception (נשׁא ) with false messages, a lawsuit (ריב) about the success of evildoers, unreliability (root כזב), seduction (פתה), and absurd commands. Several times God responds to his prophet—a sign that he respects Jeremiah’s complaints and tries to overcome his queries. The dialogues between YHWH and Jeremiah mirror questions and problems of a believing …

Editorial, Martin F. Hanna, Oliver M. Glanz

Andrews University Seminary Studies (AUSS)

This is the Editorial for Vol 60.1

"Politics After Christendom: Political Theology In A Fracturedworld" [Reivew] / Vandrunen, David., Nicholas P. Miller

Andrews University Seminary Studies (AUSS)

This is a book review

"Planting A Church Without Losing Your Soul" [Review] / Morey, Tim., Michelet William

Andrews University Seminary Studies (AUSS)

This is a book review

"A New Look At Atonement In Leviticus: The Meaning And Purpose Of Kipper Revisited " [Review] / Greenberg, James. A., Slaviša Janković

Andrews University Seminary Studies (AUSS)

This is a book review

For The Church, Sarah Moss

The Voice

No abstract provided.

Zooming In On Zebrafish Findings, Lydia Post

The Voice

No abstract provided.

Nursing Student Helps Two Patients At 30,000 Feet, Mikaela Mackey

The Voice

No abstract provided.

From Grey To Green: Reflections On Establishing An Urban Garden At Trinity College Dublin, Mariana P. Silva, Anangi Sumalde, Eleanor Flora Mullen, Simon Benson, Rachel Joanne Goodband, Conor O'Reilly, Nour Boulahcen

European Journal of Food Drink and Society

Urban gardens can be a part of the combined efforts of many to combat climate change and the associated risks posed by rapid urbanisation. These gardens can take shape on private, communal, or institutional scales, including urban educational campuses, where the teaching of sustainable gardening along with general knowledge about nature and ecology can benefit students, staff, and the wider community. This reflective piece centres on the experience of developing the Trinity Urban Garden (TUG) at Trinity College Dublin in Ireland. While hoping to overcome the worry that the tiny, seemingly inhospitable plot may not allow for a garden to …

Harnessing Ireland’S Food Heritage – The Role Of The Artisan Food Producer In Ireland’S Food Tourism Offering, Margaret Connolly, Rebecca O'Flynn

European Journal of Food Drink and Society

This research paper examines the role of the artisan food producer, not just as an entrepreneur and service provider but with a focus on how they contribute to the preservation of Ireland’s food culture and heritage. Using a qualitative methodology and in keeping with a phenomenological approach, in-depth interviews were conducted with a purposeful sample of ten artisan food producers from different parts of Ireland. A thematic analysis of the responses was carried out, with a desire to let the voice of the artisans themselves tell their story. The research shows that through the conservation and use of traditional ingredients, …

The Literary Gestalt Of The Restaurant Review, Anke Klitzing

European Journal of Food Drink and Society

The restaurant review is a quintessential form of gastronomic writing, but it has rarely been studied in terms of its literary form. This paper investigates the literary gestalt of restaurant reviews through a gastrocritical reading of two reviews by the Irish restaurant critic Helen Lucy Burke. It concludes that restaurant reviews typically include mimesis and evocative descriptions, a meal plot, inherent tension due to the performance character of the restaurant meal and incorporation anxiety, and a combination of phenomenological and ethnographic reporting. These literary features serve to make reviews an accurate and reliable account of the reviewer’s immersive experience, to …

Eristalis Tenax Movement Behavior In Response To Light, Temperature, And Food, Jeffery J. Zheng, Zdena M. Janderova, Jason D. Lang

Georgia Journal of Science

Drone flies, Eristalis tenax (Diptera: Syrphidae), are important generalist pollinators and visit flowers globally that range widely in color. The flies’ photoreceptors allow them to sense light wavelengths between 300-600 nm and E. tenax exhibit a positive phototactic response. To understand the effects of light on E. tenax movement, we conducted two-choice behavioral tests to determine their phototactic response to different wavelengths of light across the spectrum (ultraviolet to red light, plus full spectrum white light). The drone flies moved most and quickest toward sunlight, with almost twice the percentage of flies moving toward sunlight than toward black and …

Utilizing Culturally Responsive Strategies To Inspire African American Female Participation In Cybersecurity, Deanna Bailey, Michel Kornegay, Ladawn Partlow, Charnee Bowens, Karen Gareis, Kevin Kornegay

Journal of Pre-College Engineering Education Research (J-PEER)

The number of African American females participating in cyber fields is significantly low. Science, technology, engineering, and mathematics (STEM) education requires a new approach to student engagement to increase African American female participation in cybersecurity. The most common approach to engaging more African American females in STEM is to provide students access to professional images or role models active in STEM; however, more is needed. More race-centered strategies beyond role modeling are necessary to attract and retain African American females in STEM. Research studies show that integrating personal experiences and making cultural connections can help improve student participation in STEM …

“These Are Our Saints:” A Lourdes Shrine, The St. Coletta School For Exceptional Children, And The Catholic Remaking Of Cognitive Disability, Andrew Walker-Cornetta

Religion

This chapter appears from the book American Patroness: Marian Shrines and the Making of US Catholicism by Katherine Dugan and Karen E. Park, Editors.

"'These Are Our Saints:' A Lourdes Shrine, the St. Coletta School for Exceptional Children, and the Catholic Remaking of Cognitive Disability" focuses on a Lourdes shrine on the campus of what was once perhaps the most celebrated institution in the United States for persons with cognitive disabilities. It takes this site as a window onto mid-twentieth century Catholic efforts to re-imagine cognitive difference and highlights the importance of Marian devotional grammars to those efforts.

Integraciones Hemisféricas (Hemispheric Integrations), Amy Hume, Amy Chaffee, Sarah Nichols, Oscar Quiroz, Jersten Ray Seraile

Theatre: Faculty Scholarship

This article continues the tradition of publishing an annual conference “plenary” article. The Voice and Speech Trainers Association (VASTA), this journal’s sponsoring organization, met in person from July 10–14, 2023 for its 36th annual conference, co-hosted by Centro de Estudios Para el uso de la Voz (CEUVOZ) for their Second International Meeting of Voice and Speech. VASTA and CEUVOZ members and delegates met in La Paz, Mexico, for “Integraciones Hemisféricas/Hemispheric Integrations: Theoretical Frameworks for the Future of Vocal Practice and Pedagogy.” There was also an online element to the conference, with member presentations made available on a digital …

Senate Journal History, Colorado General Assembly

Colorado House and Senate Journals

No abstract provided.

Discovery And Validation Of Genes Driving Drug-Intake And Related Behavioral Traits In Mice., Tyler A. Roy, Jason A. Bubier, Price E Dickson, Troy Wilcox, Juliet Ndukum, James Clark, S J Sukoff Rizzo, John C Crabbe, James M. Denegre, Karen L. Svenson, Robert E Braun, Vivek Kumar, Stephen A Murray, Jacqueline K White, Vivek M. Philip, Elissa J Chesler

Faculty Research 2024

Substance use disorders are heritable disorders characterized by compulsive drug use, the biological mechanisms for which remain largely unknown. Genetic correlations reveal that predisposing drug-naïve phenotypes, including anxiety, depression, novelty preference and sensation seeking, are predictive of drug-use phenotypes, thereby implicating shared genetic mechanisms. High-throughput behavioral screening in knockout (KO) mice allows efficient discovery of the function of genes. We used this strategy in two rounds of candidate prioritization in which we identified 33 drug-use candidate genes based upon predisposing drug-naïve phenotypes and ultimately validated the perturbation of 22 genes as causal drivers of substance intake. We selected 19/221 KO …

Nanoparticles Carrying Antibiotics, Edward Turos, Faeez Mahzamani

USF Patents

The subject invention pertains to polyacrylate homopolymers produced from acrylolated drug monomers. The homopolymers can be produced in the form of nanoparticles. The nanoparticles comprising the homopolymers can be produced via a free radical-induced emulsion polymerization of the acrylolated drug monomers to produce an aqueous emulsion of uniformly sized nanoparticles. The homopolymers of the invention containing acrylolated antibiotic monomers can be active against Gram-positive and Gram-negative bacteria, such as Staphylococcus aureus and Escherichia coli. Accordingly, methods are provided of treating a disease, for example, an infection, by administering to a subject the homopolymers, homopolymeric nanoparticles, or emulsions containing homopolymeric nanoparticles …

Unh Hubbard Center To Offer Long-Read Genomic Sequencing, Nicholas Gosling

UNH Today Archive

No abstract provided.

Gene Regulation And Speciation In A Migratory Divide Between Songbirds, Matthew I M Louder, Hannah Justen, Abigail A Kimmitt, Koedi S Lawley, Leslie M Turner, J David Dickman, Kira E Delmore

Faculty, Staff and Students Publications

Behavioral variation abounds in nature. This variation is important for adaptation and speciation, but its molecular basis remains elusive. Here, we use a hybrid zone between two subspecies of songbirds that differ in migration - an ecologically important and taxonomically widespread behavior---to gain insight into this topic. We measure gene expression in five brain regions. Differential expression between migratory states was dominated by circadian genes in all brain regions. The remaining patterns were largely brain-region specific. For example, expression differences between the subspecies that interact with migratory state likely help maintain reproductive isolation in this system and were documented in …

Novel Techniques In Imaging Congenital Heart Disease: Jacc Scientific Statement, Ritu Sachdeva, Aimee K Armstrong, Rima Arnaout, Lars Grosse-Wortmann, B Kelly Han, Luc Mertens, Ryan A Moore, Laura J Olivieri, Anitha Parthiban, Andrew J Powell

Faculty, Staff and Students Publications

Recent years have witnessed exponential growth in cardiac imaging technologies, allowing better visualization of complex cardiac anatomy and improved assessment of physiology. These advances have become increasingly important as more complex surgical and catheter-based procedures are evolving to address the needs of a growing congenital heart disease population. This state-of-the-art review presents advances in echocardiography, cardiac magnetic resonance, cardiac computed tomography, invasive angiography, 3-dimensional modeling, and digital twin technology. The paper also highlights the integration of artificial intelligence with imaging technology. While some techniques are in their infancy and need further refinement, others have found their way into clinical workflow …

Enhancing The Zebra Optimization Algorithm With Chaotic Sinusoidal Map For Versatile Optimization, D Anand, Osamah Ibrahim Khalaf, G Rajesh Chandra

Iraqi Journal for Computer Science and Mathematics

In this study, the Chaotic Sinusoidal Map (CSM)-enhanced Zebra Optimization Algorithm (CZOA) is introduced. CZOA combines CSM's integration strengths with ZOA's optimization skills. ZOA already exhibits great optimization capabilities, but the addition of CSM increases its potential even more. This addition greatly strengthens ZOA's exploration and exploitation skills and increases its flexibility for various optimization tasks. CZOA outperforms both the original ZOA and contemporary optimisation methods on23 benchmark functions, including high-dimensional (FD), multimodal (MM), and unimodal (UM) challenges. Using the chaos of CSM to investigate regional optimal and determine better convergence and exploration-exploitation equilibrium are shown by CZOA, which also …

Antiviral Effects Of Micafungin Against Pteropine Orthoreovirus, An Emerging Zoonotic Virus Carried By Bats, Eiichi Hondo, Tetsufumi Katta, Ayato Sato, Naoya Kadofusa, Tomoki Ishibashi, Hiroshi Shimoda, Hirokazu Katoh, Atsuo Iida

Faculty, Staff and Student Publications

Bat-borne emerging zoonotic viruses cause major outbreaks, such as the Ebola virus, Nipah virus, and/or beta coronavirus. Pteropine orthoreovirus (PRV), whose spillover event occurred from fruits bats to humans, causes respiratory syndrome in humans widely in South East Asia. Repurposing approved drugs against PRV is an effective tool to confront future PRV pandemics. We screened 2,943 compounds in an FDA-approved drug library and identified eight hit compounds that reduce viral cytopathic effects on cultured Vero cells. Real-time quantitative PCR analysis revealed that six of eight hit compounds significantly inhibited PRV replication. Among them, micafungin used clinically as an antifungal drug, …