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Articles 59431 - 59460 of 733905
Full-Text Articles in Entire DC Network
Early Renal Denervation Attenuates Cardiac Dysfunction In Heart Failure With Preserved Ejection Fraction, Jake E. Doiron, Zhen Li, Xiaoman Yu, Kyle B. Lapenna, Heather Quiriarte, Timothy D. Allerton, Kashyap Koul, Andrew Malek, Sanjiv J. Shah, Thomas E. Sharp, Traci T. Goodchild, Daniel R. Kapusta, David J. Lefer
Early Renal Denervation Attenuates Cardiac Dysfunction In Heart Failure With Preserved Ejection Fraction, Jake E. Doiron, Zhen Li, Xiaoman Yu, Kyle B. Lapenna, Heather Quiriarte, Timothy D. Allerton, Kashyap Koul, Andrew Malek, Sanjiv J. Shah, Thomas E. Sharp, Traci T. Goodchild, Daniel R. Kapusta, David J. Lefer
School of Graduate Studies Faculty Publications
BACKGROUND: The renal sympathetic nervous system modulates systemic blood pressure, cardiac performance, and renal function. Pathological increases in renal sympathetic nerve activity contribute to the pathogenesis of heart failure with preserved ejection fraction (HFpEF). We investigated the effects of renal sympathetic denervation performed at early or late stages of HFpEF progression. METHODS AND RESULTS: Male ZSF1 obese rats were subjected to radiofrequency renal denervation (RF-RDN) or sham procedure at either 8 weeks or 20 weeks of age and assessed for cardiovascular function, exercise capacity, and cardiorenal fibrosis. Renal norepinephrine and renal nerve tyrosine hydroxylase staining were performed to quantify denervation …
Disruption Of The Sorghum Circadian Clock Impacts Sorghum-Sugarcane Aphid Interaction Dynamics And Aphid Feeding Behavior, Kumar Shrestha, Prince Zogli, Lise Pingault, Sajjan Grover, Juan Betancurt Cardona, Joe Louis
Disruption Of The Sorghum Circadian Clock Impacts Sorghum-Sugarcane Aphid Interaction Dynamics And Aphid Feeding Behavior, Kumar Shrestha, Prince Zogli, Lise Pingault, Sajjan Grover, Juan Betancurt Cardona, Joe Louis
Department of Entomology: Faculty Publications
Circadian clocks play a pivotal role in orchestrating metabolic rhythms in response to environmental stress. Sorghum bicolor (sorghum), a multipurpose cereal crop, suffers severe growth and yield reduction due to feeding by sugarcane aphids (SCA; Melanaphis sacchari), which are phloem-feeding pests. Previously, it has been shown that sorghum utilizes a multitude of defense mechanisms to curb SCA colonization. However, our understanding of the impact of circadian clock on sorghum-aphid interaction dynamics is limited. To explore this, a time-series transcriptomics was conducted on sorghum plants in disrupted circadian rhythm with and without SCA infestation. Transcriptomic analysis revealed a total of …
Frequency Specific Optogenetic Stimulation Of The Locus Coeruleus Induces Task-Relevant Plasticity In The Motor Cortex, Ching-Tzu Tseng, Hailey F Welch, Ashley L Gi, Erica Mina Kang, Tanushree Mamidi, Sahiti Pydimarri, Kritika Ramesh, Alfredo Sandoval, Jonathan E Ploski, Catherine A Thorn
Frequency Specific Optogenetic Stimulation Of The Locus Coeruleus Induces Task-Relevant Plasticity In The Motor Cortex, Ching-Tzu Tseng, Hailey F Welch, Ashley L Gi, Erica Mina Kang, Tanushree Mamidi, Sahiti Pydimarri, Kritika Ramesh, Alfredo Sandoval, Jonathan E Ploski, Catherine A Thorn
Faculty, Staff and Student Publications
The locus ceruleus (LC) is the primary source of neocortical noradrenaline, which is known to be involved in diverse brain functions including sensory perception, attention, and learning. Previous studies have shown that LC stimulation paired with sensory experience can induce task-dependent plasticity in the sensory neocortex and in the hippocampus. However, it remains unknown whether LC activation similarly impacts neural representations in the agranular motor cortical regions that are responsible for movement planning and production. In this study, we test whether optogenetic stimulation of the LC paired with motor performance is sufficient to induce task-relevant plasticity in the somatotopic cortical …
Place-Based Education: A Pedagogy Of Community
Place-Based Education: A Pedagogy Of Community
The International Journal of Ecopsychology (IJE)
Every place, no matter how seemingly mundane or described as ‘exotic,’ has a story—a human story involving culture (history, language, migration, etc.); a natural story involving land and water, plants and animals, and other natural phenomena; and a story that combines the two—humans in the natural space and their impact on that space. The degree to which we know the story of a place informs our connection to that place, be it positive, negative, or neutral. The incorporation of these stories—the cultural, historical, and ecological stories of a place—into school curricula is known as place-based education (PBE) and is the …
Cascades Ecopsychology Conference, July 24-27
Cascades Ecopsychology Conference, July 24-27
The International Journal of Ecopsychology (IJE)
No abstract provided.
Land Acknowledgement
The International Journal of Ecopsychology (IJE)
No abstract provided.
Psychological Athetosis: The Disjunctive Force Of The Unrepresentable
Psychological Athetosis: The Disjunctive Force Of The Unrepresentable
The International Journal of Ecopsychology (IJE)
In contrast to descriptions of a familiar and bonded-with “sense of place,” S. Freud employed a German definition of the term and experience as “unhomely” (Unheimliche) (1919, Das Unheimliche) -- “The Uncanny.” He argued that the uncanny is an intrusion of the dreadful into the familiar and thus, it is here proposed, signals a radical departure from known ground. Similarly, Kaplan and Kaplan (1974, 1977, 1989), in their studies of landscape preferences, employed the dimensions of ‘mystery’ and ‘complexity’ as a means for understanding an innate evolutionary rubric for assessing a given terrain in terms of …
Spectrum, Volume 52, Issue 3, Sacred Heart University
Spectrum, Volume 52, Issue 3, Sacred Heart University
Newspapers (Obelisk & Spectrum)
Highlights include: SHU to purchase Notre Dame High School for $15 Million -- New Executive Director of Undergraduate Admissions --Mixtape Art Gallery, Eco To-Go at 63's Leaves Students Unimpressed -- SHU Shares Because SHU Cares -- Finding Weekly Peace through Guided Meditation -- Celebrating Love and Laughter: Valentine's Day at SHU -- Sports: Men's Golf Teeing Up for Last NEC Season -- The Powerhouse of Pioneers: Women's Wresting
The Relative Strength Of Managerial Abuse, Emotion Regulation, And Displaced Aggression On Life Satisfaction, Mikhail Lyublinsky
The Relative Strength Of Managerial Abuse, Emotion Regulation, And Displaced Aggression On Life Satisfaction, Mikhail Lyublinsky
Walden Dissertations and Doctoral Studies
The potential for negative experiences in the workplace, such as managerial abuse (i.e., the inappropriate and harmful behavior of managers towards subordinates, including verbal aggression and unfair treatment), presents significant obstacles to employee satisfaction and overall well-being. Although ample evidence has supported the detrimental impact of managerial abuse on employees' life satisfaction, the influence of other factors such as the ability to regulate one’s emotional reactions and/or vent one’s anger by displacing it on someone without the power to retaliate may further impact one’s satisfaction with life. Informed by the theory of displaced aggression, the purpose of this quantitative, nonexperimental, …
Multifaceted Roles For Stat3 In Gammaherpesvirus Latency Revealed Through In Vivo B Cell Knockout Models, Chad H Hogan, Shana M Owens, Glennys V Reynoso, Yifei Liao, Thomas J Meyer, Monika A Zelazowska, Bin Liu, Xiaofan Li, Anna K Grosskopf, Camille Khairallah, Varvara Kirillov, Nancy C Reich, Brian S Sheridan, Kevin M Mcbride, Benjamin E Gewurz, Heather D Hickman, J Craig Forrest, Laurie T Krug
Multifaceted Roles For Stat3 In Gammaherpesvirus Latency Revealed Through In Vivo B Cell Knockout Models, Chad H Hogan, Shana M Owens, Glennys V Reynoso, Yifei Liao, Thomas J Meyer, Monika A Zelazowska, Bin Liu, Xiaofan Li, Anna K Grosskopf, Camille Khairallah, Varvara Kirillov, Nancy C Reich, Brian S Sheridan, Kevin M Mcbride, Benjamin E Gewurz, Heather D Hickman, J Craig Forrest, Laurie T Krug
Faculty, Staff and Student Publications
Cancers associated with the oncogenic gammaherpesviruses, Epstein-Barr virus and Kaposi sarcoma herpesvirus, are notable for their constitutive activation of the transcription factor signal transducer and activator of transcription 3 (STAT3). To better understand the role of STAT3 during gammaherpesvirus latency and the B cell response to infection, we used the model pathogen murine gammaherpesvirus 68 (MHV68). Genetic deletion of STAT3 in B cells of CD19cre/+Stat3f/f mice reduced peak MHV68 latency approximately sevenfold. However, infected CD19cre/+Stat3f/f mice exhibited disordered germinal centers and heightened virus-specific CD8 T cell responses compared to wild-type (WT) littermates. To circumvent the systemic immune alterations observed in …
Office Of Research, Economic Engagement And Outreach Update, February 14, 2024, Office Of Research, Economic Engagement And Outreach
Office Of Research, Economic Engagement And Outreach Update, February 14, 2024, Office Of Research, Economic Engagement And Outreach
Office of Research, Economic Engagement and Outreach
No abstract provided.
Sugar-Binding And Split Domain Combinations In Repeats-In-Toxin Adhesins From Vibrio Cholerae And Aeromonas Veronii Mediate Cell-Surface Recognition And Hemolytic Activities, Mustafa Sherik, Robert Eves, Shuaiqi Guo, Cameron J Lloyd, Karl E Klose, Peter L Davies
Sugar-Binding And Split Domain Combinations In Repeats-In-Toxin Adhesins From Vibrio Cholerae And Aeromonas Veronii Mediate Cell-Surface Recognition And Hemolytic Activities, Mustafa Sherik, Robert Eves, Shuaiqi Guo, Cameron J Lloyd, Karl E Klose, Peter L Davies
Faculty, Staff and Student Publications
Many pathogenic Gram-negative bacteria use repeats-in-toxin adhesins for colonization and biofilm formation. In the cholera agent Vibrio cholerae, flagellar-regulated hemagglutinin A (FrhA) enables these functions. Using bioinformatic analysis, a sugar-binding domain was identified in FrhA adjacent to a domain of unknown function. AlphaFold2 indicated the boundaries of both domains to be slightly shorter than previously predicted and assisted in the recognition of the unknown domain as a split immunoglobulin-like fold that can assist in projecting the sugar-binding domain toward its target. The AlphaFold2-predicted structure is in excellent agreement with the molecular envelope obtained from small-angle X-ray scattering analysis of …
2024-02-14 Super Bowl 58 Recap: The Chiefs Announce Their Dynasty, George Burquest
2024-02-14 Super Bowl 58 Recap: The Chiefs Announce Their Dynasty, George Burquest
The Spectator Online
No abstract provided.
Developing Expert Scientific Consensus On The Environmental And Societal Effects Of Marine Artificial Structures Prior To Decommissioning, Antony M. Knights, Anaëlle J. Lemasson, Louise B. Firth, Todd Bond, Jeremy Claisse, Joop W.P. Coolen, Andrea Copping, Jennifer Dannheim, Michela De Dominicis, Steven Degraer, Michael Elliott, Paul G. Fernandes, Ashley M. Fowler, Matt Frost, Lea Anne Henry, Natalie Hicks, Kieran Hyder, Sylvia Jagerroos, Daniel O.B. Jones, Milton Love, Christopher P. Lynam, Peter I. Macreadie, Joseph Marlow, Ninon Mavraki, Dianne Mclean, Paul A. Montagna, David M. Paterson, Martin Perrow, Joanne Porter, Debbie J.F. Russell, Ann Scarborough Bull, Michaela Schratzberger, Brooke Shipley, Sean Van Elden, Jan Vanaverbeke, Andrew Want, Stephen C.L. Watson, Thomas A. Wilding, Paul Somerfield
Developing Expert Scientific Consensus On The Environmental And Societal Effects Of Marine Artificial Structures Prior To Decommissioning, Antony M. Knights, Anaëlle J. Lemasson, Louise B. Firth, Todd Bond, Jeremy Claisse, Joop W.P. Coolen, Andrea Copping, Jennifer Dannheim, Michela De Dominicis, Steven Degraer, Michael Elliott, Paul G. Fernandes, Ashley M. Fowler, Matt Frost, Lea Anne Henry, Natalie Hicks, Kieran Hyder, Sylvia Jagerroos, Daniel O.B. Jones, Milton Love, Christopher P. Lynam, Peter I. Macreadie, Joseph Marlow, Ninon Mavraki, Dianne Mclean, Paul A. Montagna, David M. Paterson, Martin Perrow, Joanne Porter, Debbie J.F. Russell, Ann Scarborough Bull, Michaela Schratzberger, Brooke Shipley, Sean Van Elden, Jan Vanaverbeke, Andrew Want, Stephen C.L. Watson, Thomas A. Wilding, Paul Somerfield
School of Biological and Marine Sciences
Thousands of artificial (‘human-made’) structures are present in the marine environment, many at or approaching end-of-life and requiring urgent decisions regarding their decommissioning. No consensus has been reached on which decommissioning option(s) result in optimal environmental and societal outcomes, in part, owing to a paucity of evidence from real-world decommissioning case studies. To address this significant challenge, we asked a worldwide panel of scientists to provide their expert opinion. They were asked to identify and characterise the ecosystem effects of artificial structures in the sea, their causes and consequences, and to identify which, if any, should be retained following decommissioning. …
Long Non-Coding Rnas: New Insights In Neurodegenerative Diseases, Adithya Anilkumar, Puneet Vij, Samantha Lopez, Sophia M. Leslie, Kyle Doxtater, Mohammad Moshahid Khan, Murali M. Yallapu, Subhash C. Chauhan, Gladys E. Maestre
Long Non-Coding Rnas: New Insights In Neurodegenerative Diseases, Adithya Anilkumar, Puneet Vij, Samantha Lopez, Sophia M. Leslie, Kyle Doxtater, Mohammad Moshahid Khan, Murali M. Yallapu, Subhash C. Chauhan, Gladys E. Maestre
School of Medicine Publications
Neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), are gradually becoming a burden to society. The adverse effects and mortality/morbidity rates associated with these NDDs are a cause of many healthcare concerns. The pathologic alterations of NDDs are related to mitochondrial dysfunction, oxidative stress, and inflammation, which further stimulate the progression of NDDs. Recently, long non-coding RNAs (lncRNAs) have attracted ample attention as critical mediators in the pathology of NDDs. However, there is a significant gap in understanding the biological function, molecular mechanisms, and potential importance of lncRNAs in NDDs. This review documents …
Androgen Exposure Impairs Neutrophil Maturation And Function Within The Infected Kidney, Teri N Hreha, Christina A Collins, Elisabeth B Cole, Rachel J Jin, David A Hunstad
Androgen Exposure Impairs Neutrophil Maturation And Function Within The Infected Kidney, Teri N Hreha, Christina A Collins, Elisabeth B Cole, Rachel J Jin, David A Hunstad
2020-Current year OA Pubs
Urinary tract infections (UTIs) in men are uncommon yet carry an increased risk for severe pyelonephritis and other complications. In models of
The Il6/Jak/Stat3 Signaling Axis Is A Therapeutic Vulnerability In Smarcb1-Deficient Bladder Cancer, Chandra Sekhar Amara, Karthik Reddy Kami Reddy, Yang Yuntao, Yuen San Chan, Danthasinghe Waduge Badrajee Piyarathna, Lacey Elizabeth Dobrolecki, David J H Shih, Zhongcheng Shi, Jun Xu, Shixia Huang, Matthew J Ellis, Andrea B Apolo, Leomar Y Ballester, Jianjun Gao, Donna E Hansel, Yair Lotan, H Courtney Hodges, Seth P Lerner, Chad J Creighton, Arun Sreekumar, W Jim Zheng, Pavlos Msaouel, Shyam M Kavuri, Nagireddy Putluri
The Il6/Jak/Stat3 Signaling Axis Is A Therapeutic Vulnerability In Smarcb1-Deficient Bladder Cancer, Chandra Sekhar Amara, Karthik Reddy Kami Reddy, Yang Yuntao, Yuen San Chan, Danthasinghe Waduge Badrajee Piyarathna, Lacey Elizabeth Dobrolecki, David J H Shih, Zhongcheng Shi, Jun Xu, Shixia Huang, Matthew J Ellis, Andrea B Apolo, Leomar Y Ballester, Jianjun Gao, Donna E Hansel, Yair Lotan, H Courtney Hodges, Seth P Lerner, Chad J Creighton, Arun Sreekumar, W Jim Zheng, Pavlos Msaouel, Shyam M Kavuri, Nagireddy Putluri
Faculty, Staff and Student Publications
SMARCB1 loss has long been observed in many solid tumors. However, there is a need to elucidate targetable pathways driving growth and metastasis in SMARCB1-deficient tumors. Here, we demonstrate that SMARCB1 deficiency, defined as genomic SMARCB1 copy number loss associated with reduced mRNA, drives disease progression in patients with bladder cancer by engaging STAT3. SMARCB1 loss increases the chromatin accessibility of the STAT3 locus in vitro. Orthotopically implanted SMARCB1 knockout (KO) cell lines exhibit increased tumor growth and metastasis. SMARCB1-deficient tumors show an increased IL6/JAK/STAT3 signaling axis in in vivo models and patients. Furthermore, a pSTAT3 selective inhibitor, TTI-101, reduces …
Secretory Leukocyte Protease Inhibitor Protects Against Severe Urinary Tract Infection In Mice, Anne L Rosen, Michael A Lint, Dayne H Voelker, Nicole M Gilbert, Christopher P Tomera, Jesús Santiago-Borges, Meghan A Wallace, Thomas J Hannan, Carey-Ann D Burnham, Scott J Hultgren, Andrew L Kau
Secretory Leukocyte Protease Inhibitor Protects Against Severe Urinary Tract Infection In Mice, Anne L Rosen, Michael A Lint, Dayne H Voelker, Nicole M Gilbert, Christopher P Tomera, Jesús Santiago-Borges, Meghan A Wallace, Thomas J Hannan, Carey-Ann D Burnham, Scott J Hultgren, Andrew L Kau
2020-Current year OA Pubs
Millions suffer from urinary tract infections (UTIs) worldwide every year with women accounting for the majority of cases. Uropathogenic
Exploring The Developmental Effects Of Antidepressants In Caenorhabditis Elegans, Alexandra Van Stone
Exploring The Developmental Effects Of Antidepressants In Caenorhabditis Elegans, Alexandra Van Stone
Annual Research Symposium
It is so important to explore the potential side effects of antidepressants especially if these side effects could lead to a future detriment to an individual’s financial and social well-being. A better understanding of these side effects in regards to human developmental issues is imperative considering issues related to mental health and depression affect a large percentage of the population. In this study, we tested if Caenorhabditis (C.) elegans could be a potential model organism to predict possible side effects associated with select antidepressants. Their developmental problems potentially encountered upon drug treatment may be encountered in humans.
Pharmacognosy And Trichomoniasis: A Scoping Review Protocol, Claire Hartwell, Melanie Arslanian, Brad Haubrich
Pharmacognosy And Trichomoniasis: A Scoping Review Protocol, Claire Hartwell, Melanie Arslanian, Brad Haubrich
Annual Research Symposium
Trichomoniasis, also called “trich”, is the most common non-viral sexually transmitted infection (STI). Its etiological agent is the protozoan parasite Trichomonas vaginalis, against which first-line antiparasitics usually work. However, resistance is on the rise. Trich has traditionally been considered a nuisance infection, with many (particularly AMAB patients) being asymptomatic. But research in recent years has begun to unravel correlations of trichomonal infections with a myriad of comorbitidies, including infertility, cancers, the pathogenesis of AIDS, and pelvic inflammatory disease (PID). Between the rise of drug resistance and the incidence of these comorbidities, new treatments are needed. In this work, we are …
Long Non-Coding Rna As A Potential Diagnostic Tool In Coronary Artery Diseases - A Systematic Review, Arthi Sri A.S, Vishnu Priya Veeraraghavan
Long Non-Coding Rna As A Potential Diagnostic Tool In Coronary Artery Diseases - A Systematic Review, Arthi Sri A.S, Vishnu Priya Veeraraghavan
Annual Research Symposium
POSTER - SYSTEMATIC REVIEW - LONG NON CODING RNAS AS DIAGNOSTIC MARKER FOR CAD
Exploring The Interplay Between Alzheimer's Disease And Periodontitis: Insights From Clinical Data And Inflammatory Biomarkers, Sandra Arun
Annual Research Symposium
Alzheimer's disease, a complex neurodegenerative disorder marked by cognitive decline, may have a intriguing link with periodontitis—a chronic inflammatory oral condition. This study investigates the literature evidence regarding the association between Alzheimer's disease and periodontitis. Our research aims to determine if individuals with periodontitis face an elevated risk of Alzheimer's and if shared inflammatory pathways underlie this association.
“Go Outside And Play!”: Backyard Playgrounds In New Yorkcity During The Progressive Era, Julia Kovatch
“Go Outside And Play!”: Backyard Playgrounds In New Yorkcity During The Progressive Era, Julia Kovatch
Historical Perspectives: Santa Clara University Undergraduate Journal of History, Series II
No abstract provided.
Academic Senate - Minutes, 2/13/2024, Academic Senate
Academic Senate - Minutes, 2/13/2024, Academic Senate
Academic Senate Minutes
No abstract provided.
Cultural Evolution: A Review Of Theoretical Challenges, Ryan Nichols, Mathieu Charbonneau, Azita Chellappoo, Taylor Davis, Miriam Haidle, Erik O. Kimbrough, Henrike Moll, Richard Moore, Thom Scott-Phillips, Benjamin Grant Purzycki, Jose Segovia-Martin
Cultural Evolution: A Review Of Theoretical Challenges, Ryan Nichols, Mathieu Charbonneau, Azita Chellappoo, Taylor Davis, Miriam Haidle, Erik O. Kimbrough, Henrike Moll, Richard Moore, Thom Scott-Phillips, Benjamin Grant Purzycki, Jose Segovia-Martin
Economics Faculty Articles and Research
The rapid growth of cultural evolutionary science, its expansion into numerous fields, its use of diverse methods, and several conceptual problems have outpaced corollary developments in theory and philosophy of science. This has led to concern, exemplified in results from a recent survey conducted with members of the Cultural Evolution Society, that the field lacks ‘knowledge synthesis’, is poorly supported by ‘theory’, has an ambiguous relation to biological evolution and uses key terms (e.g. ‘culture’, ‘social learning’, ‘cumulative culture’) in ways that hamper operationalization in models, experiments and field studies. Although numerous review papers in the field represent and categorize …
Impairment Of The Glial Phagolysosomal System Drives Prion-Like Propagation Of Huntington’S Disease, Graham Davis
Impairment Of The Glial Phagolysosomal System Drives Prion-Like Propagation Of Huntington’S Disease, Graham Davis
Theses and Dissertations
The ability of glia to tightly regulate neuronal health and homeostasis in the CNS is conserved across species. Yet, despite the ability to degrade protein aggregates, glia are vulnerable to the accumulation of neurotoxic amyloid aggregates during neurodegenerative disease progress, and even exacerbate their spread. A developing narrative highlights glia as a double-edged sword in neurodegenerative diseases: initially capable of dynamically responding to amyloid aggregate-ladened dying neurons but also capable of inducing chronic inflammation and creating seeding-competent amyloid oligomers. Thus, uncovering the mechanisms that allow glia to control aggregate deposition while preventing the neurotoxic effects and seed generation is vital …
A Systematic Review Of Fourth Industrial Revolution Technologies In Smart Irrigation: Constraints, Opportunities, And Future Prospects For Sub-Saharan Africa, Joshua Wanyama, Erion Bwambale, Shafik Kiraga, Abia Katimbo, Prossie Nakawuka, Isa Kabenge, Isaac Oluk
A Systematic Review Of Fourth Industrial Revolution Technologies In Smart Irrigation: Constraints, Opportunities, And Future Prospects For Sub-Saharan Africa, Joshua Wanyama, Erion Bwambale, Shafik Kiraga, Abia Katimbo, Prossie Nakawuka, Isa Kabenge, Isaac Oluk
Department of Agricultural and Biological Systems Engineering: Faculty Publications
The adoption of Fourth Industrial Revolution (4IR) technologies has revolutionized agricultural practices worldwide. However, their application in the context of sub-Saharan Africa remains a critical challenge. This study presents a systematic review that investigates the potential of 4IR technologies in smart irrigation. Sub- Saharan Africa faces multiple agricultural challenges, exacerbated by climate change, water scarcity, and inefficient irrigation practices. The need for sustainable, water-efficient, and data-driven irrigation systems is urgent to ensure food security and economic development in the region. This study addresses a crucial knowledge gap by assessing the constraints, opportunities, and prospects of implementing 4IR technologies for smart …
Relationship Of Tissue Dimensions And Three Captive Bolt Application Sites On Cadaver Heads From Mature Swine (Sus Scrofa Domesticus) < 200 Kg Body-Weight, Karly N. Anderson, Ashlynn A. Kirk, Jennifer Berger, Arquimides A. Reyes, Ruth Woiwode, Perle E. Zhitnitskiy, Kurt D. Vogel
Relationship Of Tissue Dimensions And Three Captive Bolt Application Sites On Cadaver Heads From Mature Swine (Sus Scrofa Domesticus) < 200 Kg Body-Weight, Karly N. Anderson, Ashlynn A. Kirk, Jennifer Berger, Arquimides A. Reyes, Ruth Woiwode, Perle E. Zhitnitskiy, Kurt D. Vogel
Department of Animal Science: Faculty Publications
Penetrating captive bolt (PCB) is a common method of euthanasia for swine but has not been evaluated for mature swine < 200 kg body weight (BW). The objectives were to determine tissue depth, brain contact plane, and visible brain tissue damage (brain damage[BD]) for the common FRONTAL (F) and alternative TEMPORAL (T) and BEHIND EAR (BE) placements for PCB use on sows and boars weighing < 200 kg. Cadaver heads were obtained from 30 sows and 30 boars (estimated BW, mean ± SD; sows: 165.8 ± 22.4 kg; boars: 173.6 ± 21.4 kg) from a slaughter establishment after electrical stunning and exsanguination. Heads were cooled at 2 to 4 °C for approximately 64 h. A Jarvis PAS-Type P 0.25R PCB with a Long Stunning Rod Nosepiece Assembly and a 3.5 GR power load was used for all PCB applications at the following placements: F–3.5 cm superior to the optic orbits at midline, T–at the depression posterior to the lateral canthus of the eye within the plane between the lateral canthus and the base of the ear, or BE–directly caudal to the pinna of the ear on the same plane as the eyes and targeting the middle of the opposite eye. For sows, the bolt path was in the brain for 10/10 (100.0%, 95% CI: 69.2% to 100.0%) F, T, and BE heads. In heads that could reliably be assessed for BD, BD was detected in 10/10 (100.0%, 95% CI: 69.2% to 100.0%) F heads, 9/9 (100.0%, 95% CI: 66.4% to 100.0%) T heads, and 0/10 (0.0%, 95% CI: 0.0% to 30.1%) BE heads. For boars, the bolt path was in the plane of the brain for 8/9 (88.9%, 95% CI: 51.8% to 99.7%) F heads, 9/10 (90.0%, 95% CI: 55.5% to 99.7%) T heads, and 11/11 (100.0%, 95% CI: 71.5% to 100.0%) BE heads. In heads that could reliably be assessed for BD, BD was detected in 8/9 (88.9%, 95% CI: 51.7% to 99.7%) F heads, 7/10 (70.0%, 95% CI: 34.8% to 93.3%) T heads, and 4/11 (36.4%, 95% CI: 10.9% to 69.2%) BE heads. Tissue depth was reported as mean ± SE followed by 95% one-sided upper reference limit (URL). For sows, total tissue thickness differed (P < 0.05) between placements (F: 49.41 ± 2.74 mm, URL: 70.0 mm; T: 62.83 ± 1.83 mm, URL: 76.6 mm; BE: 84.63 ± 3.67 mm; URL: 112.3 mm). Total tissue thickness differed (P < 0.05) between placements for boars (F: 54.73 ± 3.23 mm, URL: 77.6 mm; T: 70.72 ± 3.60 mm, URL: 96.3 mm; BE: 92.81 ± 5.50 mm; URL: 135.3 mm). For swine between 120 and 200 kg BW, the F placement may have the greatest likelihood for successful euthanasia due to the least total tissue thickness and may present less risk for failure than the T and BE placements.
Assessing The Dynamics Of Common Dolphin (Delphinus Delphis) Mother-Calf Pairs Along The South Coast Of Portugal Using Unmanned Aerial Vehicles, Joana Castro, André Cid, Alicia Quirin, Fábio L. Matos, Rui Rosa, Heidi Pearson
Assessing The Dynamics Of Common Dolphin (Delphinus Delphis) Mother-Calf Pairs Along The South Coast Of Portugal Using Unmanned Aerial Vehicles, Joana Castro, André Cid, Alicia Quirin, Fábio L. Matos, Rui Rosa, Heidi Pearson
Faculty, Staff, and Students
Maternal grouping dynamics involve trade-offs between: (1) infant protection from predation (predation hypothesis), (2) infant protection from male harassment (infant safety hypothesis), and (3) reducing scramble competition for prey resources (foraging-type scramble competition hypothesis). Using unmanned aerial vehicles, we assessed grouping dynamics in common dolphin (Delphinus delphis) groups containing mother-calf pairs to address these hypotheses. We analyzed social aspects and structural group elements using generalized additive mixed models and modeled group formation using multinomial generalized estimating equations. Calf proportion was higher in very compact groups and in groups of 10–20 individuals but decreased in larger groups. The frequency of socio-sexual …
Methods Of Treating Cognitive Impairment, Huntington Potter, Gary W. Arendash, Steven Bennett, Timothy Boyd
Methods Of Treating Cognitive Impairment, Huntington Potter, Gary W. Arendash, Steven Bennett, Timothy Boyd
USF Patents
The subject invention concerns materials and methods for treating a person or animal having cognitive impairment. In one embodiment, the method comprises administering an effective amount of one or more inflammatory mediator(s), for example, fms-related tyrosine kinase 3 (Flt3) ligand, interleukin-6 (IL-6), macrophage migration inhibitory factor (MIF), interleukin-1 (IL-1), interleukin-3 (IL-3), erythropoietin (EPO), vascular endothelial growth factor A (VEGF-A), hypoxia-inducible transcription factor (HIF-1alpha), insulin like growth factor-1 (IGF-1), tumor necrosis factor (TNF), granulocyte colony-stimulating factor (G-CSF), granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF), Stem Cell Factor (SCF), Darbepoetin (ARANESP), and metalloproteinases, to an animal or person in need of …