Digital Commons Network^™

Bi-Directional Neuro-Immune Dysfunction After Chronic Experimental Brain Injury, Rodney M Ritzel, Yun Li, Yun Jiao, Sarah J Doran, Niaz Khan, Rebecca J Henry, Kavitha Brunner, David J Loane, Alan I Faden, Gregory L Szeto, Junfang Wu

Faculty, Staff and Student Publications

Background

It is well established that traumatic brain injury (TBI) causes acute and chronic alterations in systemic immune function and that systemic immune changes contribute to posttraumatic neuroinflammation and neurodegeneration. However, how TBI affects bone marrow (BM) hematopoietic stem/progenitor cells chronically and to what extent such changes may negatively impact innate immunity and neurological function has not been examined.

Methods

To further understand the role of BM cell derivatives on TBI outcome, we generated BM chimeric mice by transplanting BM from chronically injured or sham (i.e., 90 days post-surgery) congenic donor mice into otherwise healthy, age-matched, irradiated CD45.2 C57BL/6 (WT) …

The Student Movement Volume 108 Issue 20: Breaking News: Curfew Is Now Sunset: Effective Immediately, Grace No, Reagan Mccain, Savannah Tyler, Madison Vath, Corinna Bevier, Nate Miller, Aiko J. Ayala Rivers, Andrew Francis, Ana K. Zelidon, Jonathan Clough, Abby Shim, Bella Hamann, Anna Rybachek, Melissa Moore, Nicholas Gunn

The Student Movement v. 108 (2023-2024)

HUMANS

Chivalry Not Dead: Students Spotted in Shining Armor, Grace No

Interview with the Breakfast Burrito, Interviewed by Regan McCain

VeggieTales Cast: Hot Takes From the Fridge, Interviewed by Savannah Tyler

ARTS & ENTERTAINMENT

Why the 'Daughters of the Revolution' Stay Mad, Madison Vath

Jaws 6: The Jawsical, Corinna Bevier

I UNDERSTAND MARY POPPINS' ESSENCE MORE THAN THE FILM'S WRITERS, Nate Miller

Pitagorical decision: Music Department opens Triangle Performance Major, Aiko J. Ayala Rivers

Sabrina Carpenter Comes to Berrien, Reagan McCain

NEWS

Soccer (Football) Legend Lionel Messi to Visit Berrien County, Andrew Francis

Satire: Severe Weather Stirs Mixed Emotions on …

A Power Elite Alliance And Local Environmental Policy: Elon Musk In Cameron County, Michelle Keck, Guadalupe Correa-Cabrera

Political Science Faculty Publications

The present work analyzes several aspects related to the environmental impacts that Elon Musk’s company Space Exploration Technologies (SpaceX) has had on Cameron County, Texas. Utilizing prior studies, we will focus on how the power elite impact policy at the federal, state, and local levels, specifically regarding SpaceX’s arrival to Cameron County as well as environmental policy concerning the activities at the SpaceX Starbase facility, located on Boca Chica Beach, Texas. The present analysis uses data from semi-structured interviews with key stakeholders including government officials, developers, environmentalists, and other activists in order to understand the connections between the global and …

Blocking Senescence And Tolerogenic Function Of Dendritic Cells Induced By Γδ Treg Cells Enhances Tumor-Specific Immunity For Cancer Immunotherapy, Fusheng Si, Xia Liu, Yan Tao, Yuanqin Zhang, Feiya Ma, Eddy C Hsueh, Sidharth V Puram, Guangyong Peng

2020-Current year OA Pubs

BACKGROUND: Regulatory T (Treg) cells are a key component in maintaining the suppressive tumor microenvironment and immune suppression in different types of cancers. A precise understanding of the molecular mechanisms used by Treg cells for immune suppression is critical for the development of effective strategies for cancer immunotherapy.

METHODS: Senescence development and tolerogenic functions of dendritic cells (DCs) induced by breast cancer tumor-derived γδ Treg cells were fully characterized using real-time PCR, flow cytometry, western blot, and functional assays. Loss-of-function strategies with pharmacological inhibitor and/or neutralizing antibody were used to identify the potential molecule(s) and pathway(s) involved in DC senescence …

Csf Biomarkers Of Immune Activation And Alzheimer's Disease For Predicting Cognitive Impairment Risk In The Elderly, Francis Shue, Rachel Hendrix, Jason Ulrich, Rachel L Henson, William Knight, Chengjie Xiong, Jigyasha Timsina, Yun Ju Sung, Carlos Cruchaga, David M Holtzman, Et Al.

2020-Current year OA Pubs

The immune system substantially influences age-related cognitive decline and Alzheimer's disease (AD) progression, affected by genetic and environmental factors. In a Mayo Clinic Study of Aging cohort, we examined how risk factors like APOE genotype, age, and sex affect inflammatory molecules and AD biomarkers in cerebrospinal fluid (CSF). Among cognitively unimpaired individuals over 65 (

Subcellular Pathways Through Vglut3-Expressing Mouse Amacrine Cells Provide Locally Tuned Object-Motion-Selective Signals In The Retina, Karl Friedrichsen, Jen-Chun Hsiang, Chin-I Lin, Liam Mccoy, Katia Valkova, Daniel Kerschensteiner, Josh L Morgan

2020-Current year OA Pubs

VGluT3-expressing mouse retinal amacrine cells (VG3s) respond to small-object motion and connect to multiple types of bipolar cells (inputs) and retinal ganglion cells (RGCs, outputs). Because these input and output connections are intermixed on the same dendrites, making sense of VG3 circuitry requires comparing the distribution of synapses across their arbors to the subcellular flow of signals. Here, we combine subcellular calcium imaging and electron microscopic connectomic reconstruction to analyze how VG3s integrate and transmit visual information. VG3s receive inputs from all nearby bipolar cell types but exhibit a strong preference for the fast type 3a bipolar cells. By comparing …

Design And Test Of Wpum Topography Monitor For Iqos, Rawah Azeez

Theses

With the emergence of diverse tobacco product forms, such as electronic cigarettes and heat-not-burn, the global user base has surged to an estimated 1.3 billion. In the United States, 28.3 million adults and 3.08 million middle and high school adolescents engage in tobacco product use. However, our understanding of the usage behaviors of these various products is lacking. Puff topography, which measures the inhalation patterns of tobacco products, provides a wealth of information, including puff flow rate, duration, volume, and more. This information is crucial in understanding the health effects of tobacco products and the influence of usage behavior on …

Supercook: Design Interactive Culinary Experiences With Ai Technology, Yize Peng

Theses

The project 'SuperCook' is a groundbreaking design project that explores the integration of AI with culinary apps. It aims to revolutionize the kitchen experience by connecting users to new and accessible culinary adventures through personalized recipe recommendations, real-time cooking guidance, and interactive meal planning. By leveraging AI technology, 'SuperCook' not only enhances user convenience and efficiency but also fosters a deeper engagement with cooking and promotes healthier eating habits. This thesis delves into the design process, user testing, and iterative improvements that culminated in a user-centered, intuitive, and visually appealing UI/UX solution for modern cooking enthusiasts. In designing 'SuperCook,' attention …

A Novel Goat Model To Characterize Male Fertility Following Paternal Cannabidiol Exposure, Ashlyn N. Brewer

LSU Master's Theses

Despite the increasing use of cannabidiol, both for medical and social purposes, the effect of cannabidiol on male fertility is poorly understood. Previous studies have been carried out in rodent models, but a large animal model does not exist at this time. This experiment proposes chronic cannabidiol (CBD) exposure using a goat model to understand the impact CBD has on male reproductive performance. The purpose of this project is to determine if daily exposure to CBD in male goats would impact reproductive parameters such as sperm quality and testosterone levels.

Two studies were conducted to determine the effects of CBD …

Cognitive And Economic Development, John Luke Gallup

OHSU-PSU School of Public Health Annual Conference

A burgeoning literature finds that early childhood risk factors have large causal effects on individuals' cognitive development, education and earnings, but has not assessed the impact on the economy as a whole.

Cognitive ability is the foundation of human capital and the capacity to learn. The risk factors for poor cognitive development are very high in many countries. Each risk factor also causes child mortality, making child survival a viable proxy for good cognitive development conditions. The cognitive development of current workers happened decades earlier when they were children, providing a predetermined correlate. Controlling for country characteristics, income levels and …

Simply Snake Sprites And Sounds: Snake Detection Theory In Video Games, Entropy Cramer

Scholars Week

Snake Detection Theory states that there is an innate evolutionary advantage to respond to snake stimuli stronger and faster than non-snake stimuli. This theory has been supported by studies measuring brain activity in infants looking at images of snakes (Bertels et al., 2020), reactions in wild monkeys and marmosets (Wombolt & Caine, 2016; Isbell & Etings, 2017; Van Strien et al, 2016; Dinh et al., 2021), and in peripheral attention tasks in adults (Kawai & He, 2016; Kawai & Qui, 2020; Gallup & Meyers, 2021). Also, over 53% of UK citizens report anxiety around snakes, and it is one of …

Leveraging Icpsr: Unveiling A Goldmine Of Datasets For Graduate Research, Lynette Hoelter

Bear GRADS

Join us for an insightful webinar on how the Inter-university Consortium for Political and Social Research (ICPSR) serves as a crucial resource for graduate students seeking existing datasets for their research projects. ICPSR offers a vast collection of datasets spanning various disciplines in the social and behavioral sciences (broadly defined!).

In this webinar, we will delve into the wealth of resources available through ICPSR and explore how graduate students can effectively utilize these datasets for their thesis, dissertation, or other research endeavors. From identifying relevant datasets to understanding data documentation and access procedures, attendees will gain valuable insights into leveraging …

Using Systems Thinking Tools To Inform The Implementation Of A Cysticercosis Control Program In Rural Peru, Lisset M. Dumet Poma Mba, Angela Spencer Phd, Ruth Atto Bsc, Vanessa Cruz Bsc, Percy Vilchez Mph, Seth O'Neal Md, Mph For The Cysticercosis Working Group In Peru

OHSU-PSU School of Public Health Annual Conference

Cysticercosis is an infectious disease responsible for 30-40% of acquired epilepsy in endemic areas such as rural Peru. Ring Treatment (RT) is a community-engaged cysticercosis control strategy, shown to be efficacious when delivered by research teams. We applied the Consolidated Framework for Implementation Research with additional constructs compatible with low-resource contexts in the formative evaluation to develop a protocol for implementing RT.

We included small, medium, and large municipal districts from northern Peru representing different rural primary health delivery settings. We collected 169 semi-structured and 341 network interviews. We applied Social-Network-Analysis to identify key players, roles, and collaborations to inform …

Scientific Day, 1999, Advocate Health - Midwest

Historical Documents - Combined

Aurora Health Care, Milwaukee, WI: Program for the June 4, 1999 Scientific Day. Includes an agenda, abstracts, and information on the first Annual Rieselbach Scientific Day Lecture.

Scientific Day, 2001, Advocate Health - Midwest

Historical Documents - Combined

Aurora Health Care, Milwaukee, WI: Program for the May 17, 2001 Scientific Day. Includes an agenda and abstracts for the event.

Aurora Scientific Day, 2004, Advocate Health - Midwest

Historical Documents - Combined

Aurora Health Care, Milwaukee, WI: Program for the May 20, 2004 Aurora Scientific Day. Includes an agenda and abstracts for the event.

Aurora Scientific Day, 2005, Advocate Health - Midwest

Historical Documents - Combined

Aurora Health Care, Milwaukee, WI: Program for the May 5, 2005 Aurora Scientific Day. Includes an agenda and abstracts for the event.

Scientific Day, 2007, Advocate Health - Midwest

Historical Documents - Combined

Aurora Health Care, Milwaukee, WI: Program for the May 17, 2007 Scientific Day. Includes an agenda and abstracts for the event.

Scientific Day, 2009, Advocate Health - Midwest

Historical Documents - Combined

Aurora Health Care, Milwaukee, WI: Program for the May 28, 2009 Scientific Day. Includes an agenda and abstracts for the event.

Simplicity And The Sermon On The Mount, Falon Opsahl Barton

Discernment: Theology and the Practice of Ministry

Jesus lived a life of simplicity in his possessions and his purpose. In the Sermon on the Mount, Jesus invites his disciples, then and now, into a similar life of simplicity that is fully focused on God alone in order to make whole our relationships with God, ourselves, each other, and creation. This article claims that simplicity is a primary theme of Jesus’ longest discourse, and that Jesus’ simplicity is not self-focused, but rather benefits all humanity and all creation. This article exegetes Matthew 6:25-34 specifically, and draws out some of the theological and missional implications of Jesus's model of …

The Beacon, April 4, 2024, Beacon Staff

The Beacon, 2023-2024

Uninterested or Overworked?; Typical day for Vonder Bruegge; "Manna" breaks Christian music norm; A new trilogy following "Kung Fu Panda 4"; Senior Spotlight: Madison DenHerder; TEDxNWC explores the meaning of "allegory"; Helpful tips to survive Humans vs Zombies; Where are the student participants?; Staff, students prepare for fall ResLife changes; The many hats of VB; Taylor Swift: more than an artist; Is competition cheer a sport?; Final season of intramurals is in full swing; Outdoor track and field starts off with a bang; Raider softball and baseball are full of talent; Missing Princess emerges; Beloved Festival of Culture returns;

The Impact Of The Covid-19 Pandemic On Academic Research Productivity And Faculty Performance In Palestinian Universities: A Qualitative Investigation, Jafar W. Abu Saa

An-Najah University Journal for Research - B (Humanities)

COVID-19's worldwide spread in early 2020 necessitated the implementation of various precautionary measures by governments worldwide to restrain the fast-paced propagation of the pandemic. One of the strategies called for the brief shutdown of educational establishments such as schools, colleges and universities. Objectives of the study: The present investigation intends to examine the viewpoints of Palestinian academic personnel on the influence of the Coronavirus on their research activities and academic achievements. Methodology and procedures: The study utilized a qualitative research methodology, which primarily relied on a semi-structured open-ended interview technique to collect data. Five esteemed professors from a prestigious university …

Elaborating A Human Rights Friendly Copyright Framework For Generative Ai, Christophe Geiger

Joint PIJIP/TLS Research Paper Series

This paper analyses the copyright issues related to so-called “generative AI” systems and reviews the arguments currently advanced to change the copyright regime for AI-generated works from a human rights perspective. It argues that because of the applicable human rights framework for copyright but also the anthropocentric approach of human rights the protection of creators and human creativity must be considered the point of reference when assessing future reforms with regard to copyright and generative AI systems. Consequently, the copyrightability of AI-generated outputs should be considered with utmost care and only when AI is used as a technical tool for …

Horizontal Federalism & The Big State "Problem", Elizabeth Beske

Scholarly Articles in Law Reviews & Journals

California regulates pork; does it offend the Constitution that pork producers in other states must comply with its regulations if they want to sell Californians pork? In National Pork Producers Council v. Ross, the Supreme Court emerged sharply divided in its approach to the practical extraterritorial spillover effect of the in-state regulations of a tantalizing market. Although a fractured majority of the Court upheld California’s Proposition 12 against a dormant Commerce Clause challenge, at least five Justices registered profound discomfort, with one dissenter expressly inviting consideration of the problem through the lens of other clauses. This Article analyzes “the …

Urban Expansion And Loss Of Watershed Of Eleyele Dam In Ibadan, Nigeria, Samson A. Adejumo, Solomon Osunwale

CSID Journal of Infrastructure Development

The study examined human activities contributing to the depletion of the Eleyele watershed. The activities have grown over time due to urban expansion through population growth and land and space requirements, resulting in rapid land use and land cover change. The study sourced both quantitative and qualitative data. A total of 247 pre-tested questionnaires were administered to randomly selected residents in the four communities (Eleyele, Ijokodo, Awotan, and Idi Osan) abutting the Eleyele watershed. In-depth interviews were conducted with the heads of Eleyele Waterworks, the Forestry Department, and the Oyo State Ministry of Agriculture and Natural Resources. We used Remote …

Unraveling The Evolutionary Origin Of The Complex Nuclear Receptor Element (Cnre), A Cis-Regulatory Module Required For Preferential Expression In The Atrial Chamber., Luana Nunes Santos, Ângela Maria Sousa Costa, Martin Nikolov, João E Carvalho, Allysson Coelho Sampaio, Frank E Stockdale, Gang Feng Wang, Hozana Andrade Castillo, Mariana Bortoletto Grizante, Stefanie Dudczig, Michelle Vasconcelos, Nadia Rosenthal, Patricia Regina Jusuf, Hieu T Nim, Paulo De Oliveira, Tatiana Guimarães De Freitas Matos, William Nikovits, Izabella Luisa Tambones, Ana Carolina Migliorini Figueira, Michael Schubert, Mirana Ramialison, José Xavier-Neto

Faculty Research 2024

Cardiac function requires appropriate proteins in each chamber. Atria requires slow myosin to act as reservoirs, while ventricles demand fast myosin for swift pumping. Myosins are thus under chamber-biased cis-regulation, with myosin gene expression imbalances leading to congenital heart dysfunction. To identify regulatory inputs leading to cardiac chamber-biased expression, we computationally and molecularly dissected the quail Slow Myosin Heavy Chain III (SMyHC III) promoter that drives preferential expression to the atria. We show that SMyHC III gene states are orchestrated by a complex Nuclear Receptor Element (cNRE) of 32 base pairs. Using transgenesis in zebrafish and mice, we demonstrate that …

Curriculum Subcommittee Minutes April 4, 2024, Utah State University

Educational Policies Committee

• Approval of Minutes - March 7, 2024
• Program Proposals
• Semester Course Approval Reviews -
• College of Agriculture and Applied Sciences,
• Caine College of the Arts,
• Jon M. Huntsman School of Business,
• Emma Eccles Jones College of Education and Human Services,
• College of Engineering,
• College of Humanities and Social Sciences,
• S.J. & Jessie E. Quinney College of Natural Resources,
• College of Science,
• College of Veterinary Medicine
• Other Business
• Adjourn: 2:30 pm

What Can We Learn About Teaching Excellence From Our Students? Lessons From Six Years Of Teaching Award Data, Christopher Shortell, Kris Henning, Carl Christiansen

Political Science Faculty Publications and Presentations

Teaching excellence in higher education can be defined and studied in different ways, but research efforts to date have often focused on institutional or instructor perspectives. This article uses a data set of over 500 open-ended comments submitted by Political Science undergraduates as part of a teaching award process to identify themes that matter most to students. We find that being supportive, bringing humor, enthusiasm, and passion to the classroom, and engaging students with relevant, challenging, and exciting activities are what defines teaching excellence from a student’s perspective. Building on these themes and using quotes to illustrate key concepts, we …

Do Bulk Nitrogen Isotope Ratios Capture Declines In Captive Muskox Body Condition?, Molly Cook, Garrett Savory

2024 Research and Creative Activity Day Posters

We were interested in studying muskox bulk nitrogen isotope ratios to see if these values capture declines in body condition. We were particularly interested in using archived serum from muskox at the University of Alaska Fairbanks Large Animal Research Station from 2009-2010 when there was a decline in the body condition of some individuals due to deficiency in trace minerals. Nitrogen isotope ratios can be analyzed to assess protein balance in animals. Since the lighter isotope of nitrogen (14N) is preferentially excreted in urine, the heavier isotope of nitrogen (15N) is enriched in tissues. As a result, we expect to …

Grasshoppers In Wood River: A Relic Population Of The Presumed Extinct Rocky Mountain Locust?, Luke Lawson, Derek Sikes

2024 Research and Creative Activity Day Posters

Investigation into the taxonomy of a grasshopper outbreak in rural Alaska.