Digital Commons Network^™

Shifting Approaches, Innovative Methods: Collection Histories As A Tool To Move Beyond William Fagg’S ‘Lower Niger Bronze Industry Mystery’, Imogen Coulson, Julie Hudson, Sam Nixon

Artl@s Bulletin

At the end of 2019, the British Museum launched a new research project focusing on copper alloy objects associated with the Lower Niger Bronze Industry. The aim was to increase knowledge of these objects through a combination of provenance and collection history research and scientific analysis. This paper will outline the earlier art historical-focused approach to the Lower Niger Bronzes corpus and will then describe the new research and its methodology. Initial findings will be presented through a case study of objects from the Forcados River in the Niger Delta region of present-day Nigeria. In doing so, we aim to …

Making Absences Present: The Process Of Visualizing Knowledge Production In Museum Records, Caitlin Glosser

Artl@s Bulletin

In this paper, I evaluate the development of data visualizations as an art historical approach. By visualizing data for Senufo-labeled objects in the Musée Africain de Lyon’s collection, I demonstrate how the museum’s knowledge infrastructure privileges European collectors over African makers. I use Tableau visualizations to decenter this narrative by making silences present in a more impactful manner than through text alone. The visualizations also reveal the complex role that one maker, Bèma Coulibaly, played in the life of the collection. The addition of the individual narrative to the data was necessary to bring a human element into view.

Nous …

Exploring The Utilization Of Imaging Modalities In Diagnosis Of Basal Cell Carcinoma: A Scoping Review, Mahi Basra, Lucas Shapiro, Hemangi Patel, Collin Payne, Alejando Biglione

InterLACE Research Showcase

No abstract provided.

Emoji-Based Module On The Writing Skills Of Senior High School English Language Learners, Karl Angelo R. Tabernero

Annual Research Congress for High School and Elementary Teachers, Researchers, and Scholars (ARCHERS)

Addressing the problems of poor English writing skills encountered in Senior High School (SHS) level of basic education requires innovative learning material that is responsive to the nature, needs, and interests of the present learners and to the learning gaps brought by the COVID-19 pandemic. As quality education is one of the sustainable development goals emphasized by the United Nations, the development and utilization of a flexible and transformative learning module are deemed important to provide learners with language knowledge and skills regardless of their background and status. Hence, it is in this light that the study was conducted: to …

Hugnayang Kognitibo: Pagtatala At Pagsusuri Sa Proseso Ng Pagbuo Ng Kagamitang Panturo Sa Filipino Gamit Ang Instruksiyon Sa Telebisyon - Deped Tv, Ronnel B. Agoncillo Jr.

Annual Research Congress for High School and Elementary Teachers, Researchers, and Scholars (ARCHERS)

Ang DepEd TV ay isang pambansang programa ng Kagawaran ng Edukasyon sa ilalim ng Information and Communications Technology Service - Educational Technology Unit (DepEd ICTS-ETU) na nabuo sa pagsisimula ng pandemyang COVID-19 noong 2020. Layunin nitong punan ang learning gaps na maaaring umusbong dahil sa pagbabago ng paradigma ng edukasyon tungo sa blended learning o pagkatutong nakabatay sa paggamit ng modyul o internet. Maglaon, lumitaw na mainam itong suplemento sa pagtuturo sa basic education dahil sa aksesibilidad nito at nakaeenganyong pormat ng pagtuturo. Layunin ng papel na ito ang sumusunod: (a) maitala at mataya ang naging proseso ng mga itinalagang …

The Fierce Green Fire: Vol. 14 Issue 18, Wofford College Environmental Studies Program

The Fierce Green Fire

No abstract provided.

Effects Of Delayed Hca Exposure On A Rat Model Of Bipolar Disorder, Eden Comer, Natalie Olander

23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024)

Bipolar disorder (BD) is a neuropsychological disorder featuring cyclical periods of depressive and manic behaviors. The Chase lab aims to develop a reliable animal model for BD in order to characterize its critical neurological triggers. Previous work has shown that daily injection of rat pups from postnatal day 3 through 19 (P3-P19) with homocysteic acid (HCA) produces a mixed manic and depressive state after puberty. These behaviors can be reversed by lithium treatment and involve changes in gene expression in the prefrontal cortex that are also improperly regulated in BD. Despite this model's reproducibility, we observed critical changes in the …

The Behavioral Impacts Of Iron Oxide Nanoparticle Exposure On The House Sparrow (Passer Domesticus), John Wenderski, Brooke Fox, Jacob Bergstrom, Olivia Sprys-Tellner, Peyton Hallemann, Sarah Grimes

23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024)

In response to a rapidly growing world population, there has been a dramatic increase in global urbanization and industrialization. With these increases comes increased air pollution, which includes metallic nanoparticles that are small enough to pass through an animal’s blood-gas and blood-brain barriers and cause damage. Some animals show behavioral changes in response to metallic nanoparticle exposure; for example, zinc oxide nanoparticle-exposed chicks displayed less antipredator behavior compared to controls. Additionally, mice injected with silver traveled less and more slowly than controls. Observationally, urban birds, compared to their rural conspecifics, tend to take more risks and explore more, which are …

Development Of Evidence-Based Clinical Practice Guidelines For Pediatric Patients At Risk Of Emergence Delirium, Christina Bensley

Doctor of Nursing Practice Scholarly Projects

Postoperative emergence agitation or emergence delirium (ED) is a phenomenon that can occur in patients who have undergone surgery requiring the administration of inhaled anesthetics. ED is a postoperative side effect of general anesthesia commonly experienced by pediatric patients that negatively impacts a patient’s overall postoperative experience. There is a lack of consistent standardized clinical practice guidelines for general anesthesia in pediatric or adult populations. The primary goal of this scholarly project is to develop and implement clinical practice guidelines focusing on the occurrence of postoperative ED and select adverse clinical outcomes in pediatric patients undergoing general anesthesia. The project …

Final Scholarly Project: Clinical Guidelines For The Perioperative Management Of Patients With Opioid Use Disorder Requiring Anesthesia, Jessica Kayla Joos

Doctor of Nursing Practice Scholarly Projects

Opioids have highly addictive properties that allow for high levels of misuse. Since the early 1990s, the misuse and deaths rates related to narcotics have steadily risen in the United States. Efforts to identify individuals using opioids prior to surgery have proven difficult. The number of patients misusing opioids and reporting for surgery can only be estimated due to under-reporting related to fear and self-stigma. With 50 million surgeries in the U.S. annually and 3.32 million people misusing opioids monthly, the chances of a patient with Opioid Use Disorder (OUD) presenting for anesthesia are exceptionally high. Moreover, patients who rate …

An Ecology Against The Right. Learning Uncertainty And Humility From Ecosystems, Pierre L. Ibisch, Mona Eikel-Pohen, Elias Iceman, Jake Snelling

Languages, Literatures, and Linguistics - All Scholarship

This article is a translation from the German to English. The title of the original is:

Ibisch, P.L. (2020): Eine Ökologie gegen rechts. Von Ökosystemen Unsicherheit und Demut lernen. In: Leitschuh, H., A. Brunnengräber, P.L. Ibisch, R. Loske, M. Müller, J. Sommer & E.-U. v. Weizsäcker (eds. J. Sommer, P.L. Ibisch, A. Brunnengräber): Ökologie und Heimat. Jahrbuch Ökologie 2021. Hirzel-Verlag, Stuttgart, 191-205.

Role Of Centrosomal P4.1 Associated Protein (Cpap) In Tumor Suppression, Heena Dave

MUSC Theses and Dissertations

In eukaryotic cells, centrosomes are membrane-less organelles that function as the primary microtubules organizing center with a crucial role in cell division. For accurate bipolar spindle assembly and genetic transmission between generations, fidelity in centriolar duplication is critical. Disruption in this process can cause genomic instability, which could then lead to conditions like aneuploidy, a common feature of various cancers. Among the numerous proteins associated with mammalian centrioles, the centrosomal P4.1 associated protein (CPAP) stands out for its essential role in regulating centriole duplication. Dysfunctions in CPAP have been linked to abnormalities in centriole length that can contribute to conditions …

Chromosomal 3q Amplicon Encodes Essential Regulators Of Secretory Vesicles That Drive Secretory Addiction In Cancer, Xiaochao Tan, Shike Wang, Guan-Yu Xiao, Chao Wu, Xin Liu, Biyao Zhou, Yu Jiang, Dzifa Y. Duose, Yuanxin Xi, Jing Wang, Kunika Gupta, Apar Pataer, Jack A. Roth, Michael P. Kim, Fengju Chen, Chad J. Creighton, William K. Russell, Jonathan M. Kurie

Markey Cancer Center Faculty Publications

Cancer cells exhibit heightened secretory states that drive tumor progression. Here, we identified a chromosome 3q amplicon that serves as a platform for secretory regulation in cancer. The 3q amplicon encodes multiple Golgi-resident proteins, including the scaffold Golgi integral membrane protein 4 (GOLIM4) and the ion channel ATPase secretory pathway Ca2+ transporting 1 (ATP2C1). We show that GOLIM4 recruited ATP2C1 and Golgi phosphoprotein 3 (GOLPH3) to coordinate Ca2+ -dependent cargo loading, Golgi membrane bending, and vesicle scission. GOLIM4 depletion disrupted the protein complex, resulting in a secretory blockade that inhibited the progression of 3q-amplified malignancies. In addition to its role …

No "Butts" About It: The Heavy Metal Impact Of Cigarette Litter, Faith Huff, Connor Monson, Spencer Whittington

23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024)

Cigarettes are the most common litter globally. Following smoking, the filter is left with carcinogenic compounds, tar and metals. All of which are highly toxic for wildlife, affecting reproduction, behavior and mortality rate in animals. The heavy metals that are left within the filter also have potential to leach from the cigarettes and enter the groundwater system. As these heavy metals enter the system, it leads to adverse effects on the environment and can cause detrimental health effects in humans, such as cell damage, induced carcinogenic processes and loss of cellular functions. Much research that exists currently only focuses on …

Investigating Auditory And Visual Seasonality In House Finches, Ashley Lauraine, Hannah Peterson, Jordan Winters

23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024)

Many birds receive both visual and auditory signals in mate selection, such as plumage color and song differences within conspecifics, which has implications for behavioral and communication processes. This processing of stimuli from different systems as a combined signal is also known as multimodal sensory processing. Sex hormone levels correlating with reproduction efforts vary seasonally in temperate animals, leading to changes in sensory processing as well. As the seasons progress, sex hormones (i.e. estrogen and testosterone) fluctuate, and an increase or decrease in these hormones has shown an impact on hearing in songbird species, however, less is known about the …

Modeling Dopaminergic Loss In The Zebrafish Olfactory System, Lexus Putt, Samantha Groenwold, Ted Lockett, Nathaniel Vorhees

23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024)

Zebrafish provide an ideal model to study neurodegenerative diseases and regenerative processes as they present neurogenesis and a high degree of neuroplasticity throughout their lifespan. It has been suggested that dopamine has an important role in regulating olfaction. We aimed to study the structural and functional effects of dopaminergic loss in the olfactory system. We injected 6-hydroxydopamine (6-OHDA) int the ventricular zone of adult zebrafish at the interphase between the olfactory bulbs and the telencephalon to target dopaminergic neurons in the olfactory bulb.Then, we assessed dopaminergic neural loss, markers of inflammation, morphological changes of olfactory axons, and synaptic connections. Olfactory …

Retrograde Degeneration Of The Olfactory Epithelium Following Neurotoxic Lesioning In Zebrafish, Sophia A. Farbarzhevich, Riley G. Checkley, Mackenzie T. Williams, Rachel J. Mast

23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024)

Parkinson’s Disease (PD), a neurodegenerative disease that deteriorates dopaminergic neurons in the substantia nigra, is characterized by movement deficits, sleep disturbances, mental deficits, and hallucinations. About 95% of those with PD experience olfactory dysfunction or loss of the sense of smell. Prior research found evidence of retrograde degeneration in animal models of PD, which occurs when axons degenerate proximal to the neural injury itself, beginning in the axon terminals and proceeding to the cell body. Although dopaminergic retrograde degeneration has been observed in PD models, it is unknown if this contributes to some non-motor PD’s symptoms, such as olfactory loss. …

Implications Of Iron Oxide Nanoparticle Exposure On The Auditory Physiology And Iron Bioaccumulation In House Sparrows (Passer Domesticus), Shae Johnston, Peyton Hallemann, Olivia Sprys-Tellner

23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024)

Air pollution (including particulate matter, PM) has increased as a result of a dramatic increase in urbanization. Nanoparticles within PM can be detrimental to health when inhaled., because they are small enough to bypass the blood-brain and blood-gas barriers, and can potentially accumulate in organs within the organism. For example, previous work has linked bioaccumulation of iron oxide nanoparticles (IONPS) to cancer and organ poisoning. Interestingly, in model organisms, nanoparticle exposure has also been linked to hearing deficits, suggesting that decline in hearing may be an early bioindicator of future health consequences. While the specific mechanism for this hearing deficit …

Death Stranding: A New Digital Ecology, Jordan Long

Theses and Dissertations

This essay analyzes Death Stranding, the 2019 release from contemporary game auteur Hideo Kojima. Here, I discuss the unique potentialities of this game world, detailing the ways in which Death Stranding expresses ecological perspectives. Asynchronous multiplayer serves as a unique metagame, helping to prove that play is a process of action which facilitates ecological thinking. The world of Death Stranding is filled with strange objects. The nonhuman entities that the player encounters throughout the game, for example, seem entirely alien. And yet, when these entities are properly understood, we realize that their inclusion is necessary--and natural. Your "job" in the …

“It Didn’T Hurt Me”: Patients’ And Providers’ Perspectives On Unsupervised Take‑Home Doses, Drug Diversion, And Overdose Risks In The Provision Of Medication For Opioid Use Disorder During Covid‑19 In San Juan, Puerto Rico, Roberto Abadie, Celia B. Fisher

School of Global Integrative Studies: Faculty Publications

Background During the COVID−19 pandemic, clinics offering medication for opioid use disorder (MOUD) needed to rapidly introduce unsupervised take−home dosing, while relapsing patients and patients unable to enter treatment faced increased risks of fentanyl−related overdose deaths and other drug−related harms. Based on a qualitative study of people who inject drugs (PWID) receiving MOUD treatment and MOUD staff in Puerto Rico, this paper documents the lived experiences of patients and providers during this period and the risk perceptions and management strategies to address substance misuse and drug diversion attributable to unsupervised take−home−dose delivery

Methods In−depth qualitative interviews were conducted with patients …

Fishing For Answers: Studying Hypoxia's Effects On The Zebrafish Olfactory Epithelium, Madelyn Yakes, Skylar Dewitt, Gracie Hill

23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024)

Hypoxia, i.e. low oxygen, is a physiologically damaging condition found in many health conditions such as ischemic stroke, sleep apnea, asthma, etc. Additionally, decreased dissolved oxygen levels in aquatic environments occur as a result of climate change. Zebrafish offer an excellent model to study hypoxia due to extensive neuroplasticity and injury-induced cell proliferation, which allows them to recover lost function in the central nervous system (CNS). We have shown that olfaction (i.e., the ability to smell), decreases in response to hypoxic exposure in adult zebrafish. Thus, it is important to study the structural abnormalities underlying this loss of smell. Olfactory …

Explorehope Summer Camps: Amazing Animal Abilities, Hannah Sturgeon, Alyssa Archer, Ashley Lauraine

23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024)

Did you know that mice can hear sounds that humans cannot? Or that birds and bees can see colors we can only dream of? ExploreHope is an organization on the Hope College campus that has been hosting summer camps for elementary to high school level students for 27 years. The ExploreHope Amazing Animal Abilities camp for students in grades 6 through 9 will explore the many incredible sensory abilities of animals. This camp will teach participants about a vast variety of sensory systems observed across the animal kingdom including the visual, auditory, and olfactory systems, mechanoreception and kinesthetics, and the …

Hope College Abstracts: 23rd Annual Celebration Of Undergraduate Research And Creative Activity, Hope College

23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024)

The 23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity was held on April 12, 2024 in the Richard and Helen DeVos Fieldhouse at Hope College and featured student-faculty collaborative research projects. This program is a record reflective of those projects between the 2023-2024 academic year.

Ucc Minutes Apr 12, 2024, Undergraduate Curriculum Committee

Undergraduate Currirculum Committee Minutes

No abstract provided.

Unveiling Sensory Gaps: A Study On Zebrafish Alanine Taste Blindness And The Consequential Neurotoxic Impact On Dopaminergic Neurons In Motor Regions, Samantha Groenwold, Mackenzie Korff

23rd Annual A. Paul and Carol C. Schaap Celebration of Undergraduate Research and Creative Activity (2024)

Parkinson’s Disease (PD) is a neurodegenerative disorder characterized by deficits in motor functions including loss of coordination and hypertonia. Dopaminergic (DA) neuronal death is found in the substantia nigra and reward centers of the brain in PD patients. Smell loss is also associated with patients with PD as DA neurons are found in the Olfactory Bulb (OB), the brain structure that processes odor signals. We use zebrafish as a model to study neurodegenerative diseases, including PD, as they can regenerate neurons throughout their lifespan. We have established a model to study DA loss in the zebrafish olfactory system. To do …

Immersive Japanese Language Learning Web Application Using Spaced Repetition, Active Recall, And An Artificial Intelligent Conversational Chat Agent Both In Voice And In Text, Marc Butler

MS in Computer Science Project Reports

In the last two decades various human language learning applications, spaced repetition software, online dictionaries, and artificial intelligent chat agents have been developed. However, there is no solution to cohesively combine these technologies into a comprehensive language learning application including skills such as speaking, typing, listening, and reading. Our contribution is to provide an immersive language learning web application to the end user which combines spaced repetition, a study technique used to review information at systematic intervals, and active recall, the process of purposely retrieving information from memory during a review session, with an artificial intelligent conversational chat agent both …

Hormetic Modulation Of On Mtor Mitochondria Cross Talk For Mitigation Of Cellular Aging, Mahalakshmi R

Theses and Dissertations

Cellular aging is a gradual process involving structural and functional deterioration of cells. Mitochondria, the biological clock in cells, are known to play a crucial role in the progression of cell aging. According to the mitochondrial free radical theory of aging, oxidative phosphorylation in the mitochondria produces free radicals, such as, reactive oxygen species (ROS), which lead to oxidative stress in cells. This, in turn, results in mitochondrial dysregulation, and eventually causes degeneration of cellular components, thereby propagating cell aging. However, it is to be underscored that aging, at its core, is a multifaceted phenomenon that involves a number of …

Heterogeneity And Plasticity Of The Naïve Cd4+ T Cell Compartment, Alia Sajani

Dartmouth College Ph.D Dissertations

Recent studies have illuminated unexpected heterogeneity in the naïve T cell compartment. Using single cell RNA sequencing of mouse naïve CD4⁺ T cells, we identified 5 unique transcriptional subsets within the naïve CD4⁺ T cell compartment. These include a quiescence cluster (T^Q) marked by Klf2, Klf6, Jun and Btg2, a memory-like cluster (T^MEM) marked by Ccr7, Il7r and Tcf7, a TCR reactive cluster (T^TCR) marked by Cd5, Cd6 and Nr4a1, an IFN responsive cluster (T^IFN) marked by Stat1, Irf7 and Ifit1 and …

Occentatia: Community And Escapism Through Queer World-Building, Ian Cooper

Theses and Dissertations

55 PagesOccentatia is an investigation into queer world-building, inspired by fantasy games, electronic media, and the culture of the ‘90s and early 2000’s. Built by a diverse creative team of 22 artists, audiences and readers are invited to explore the medieval-Gothic world of Occentatia through drawing and illustration, video and audio, sculpture, and installation This supportive statement guides readers through inspirations, socially engaged art, insight into characters, and the development of fantastical narratives. I hope to provide clarity to my practice, displaying the need for more research on the role fantasy and gaming play in understanding queer identities, aesthetics, and …

Still Life Happens, Mary Ann Crabtree

Theses and Dissertations

After dedicating over two years to pursuing an MFA degree focused on ceramics and sculpture, I find myself transported back to a familiar setting from my past: a tableau reminiscent of what remained in the dining space after four young children finished a meal and exited the room. Revisiting the scene recalls happy times despite the disorder. What helped maintain my sanity during the relentless repetition of the every-day-long task was the realization that every day, innocents are learning to become aware of the world around them. For my thesis exhibition, I created a tableau as a loud reminder of …