Digital Commons Network^™

Exploring Novel Nutrient Acquisition Mechanisms For Maintaining Energy Metabolism In Toxoplasma Gondii, Melanie Key

All Dissertations

Toxoplasma gondii is an infectious intracellular parasite that establishes infection within various mammalian hosts, including humans. Toxoplasma infects approximately one-third of the global population, making it an impactful pathogen of study. T. gondii is the causative agent of toxoplasmosis, an opportunistic infection that causes severe illness or fatality in immunocompromised individuals or pregnant women. The parasite possesses a very effective invasion strategy, allowing it to cross different tissue types to disseminate infection across the placental and blood-brain barrier. Although there are a few treatments for acute toxoplasmosis, these drugs can produce adverse side effects. These options are not effective against …

An Exploration Of The Efficacy Of Virtual Agents Within Smartphone Mental Health Applications, Stephanie Six

All Dissertations

The prevalence of depression in the U.S. has increased over the past decade, leading to an all-time-high during the COVID-19 pandemic (WHO, 2022). With this increase, the number of mental health applications (MHealth apps) on virtual e-stores increases in tandem. Despite this expanding number of MHealth apps, few demonstrate a foundation in empirical research. One design factor that may influence usability and effectiveness is the inclusion of virtual agents. Three studies were conducted to investigate users’ preferences for a variety of characteristics associated with virtual agents. In Experiment 1, users completed a single-session, three-stage CBT-based interaction with virtual characters and …

Evolution And Biogeography Of High Appalachian Rove Beetles (Staphylinidae), Adam Haberski

All Dissertations

The southern Appalachian Mountains are a region of great species richness and a center of endemism in many taxa, including flightless arthropods. High elevation refugia have facilitated the persistence of ancient lineages (paleoendemism) and in situ speciation (neoendemism), but their ubiquity, timing, and relative importance is unknown. Congruent patterns among co-distributed, but independent taxa might illuminate common drivers of Appalachian endemism. In this dissertation, I investigated the influence of allopatric speciation, geography, and paleoclimate events on the diversification of endemic species in two genera of rove beetles (Coleoptera, Staphylinidae), Lathrobium Gravenhorst and Ischnosoma Stephens, using an integrative morphological and molecular …

Tin-Silver As A Novel Biodegradable Metallic Biomaterial, Charley Goodwin

All Dissertations

The Essure device is a non-hormonal, minimally-invasive, permanent female sterilization implant, removed from the market due to an increase in adverse events, hypothesized to be caused by corrosion of the Sn-Ag component of the implant. The goals of this dissertation were to first develop implant retrieval methods for Essure devices and surrounding tissue, documenting signs of degradation and metallic degradation products, then to characterize the electrochemical behavior of Sn-Ag in biologically representative environments and finally, to assess the biological interaction of Sn-Ag. Retrieval analyses developed successful methods, qualifying the degree of corrosion, primarily of the Sn-Ag component and finding Sn …

With Great Power: Using Comics To Facilitate Discussion Of Systemic Oppression In Higher Education Literature Classes, Keri Crist-Wagner

All Dissertations

Undergraduate student participation in general education classes constitutes a point of struggle for many educators, especially when it comes to lessons centered around systems of oppression like racism, sexism, or heterosexism. Using both constructivism and counter storytelling as theoretical frameworks, this multi-method phenomenological case study explored the experiences of undergraduate honors students in a semester long general education literature class. The purpose of this study was to 1) explore how comics can be used as a pedagogical tool in higher education classrooms to facilitate discussion of systems of oppression, 2) assess the ways in which students interacted with comics, and …

Hunting For Agriculture: Unraveling Ecological Motivations In The Transition To Farming By The Fremont Cultural Complex, Ryan Mcgrath

All Graduate Theses and Dissertations, Fall 2023 to Present

This study explored the profound human history shift from foraging to agriculture, focusing on Utah's Fremont cultural complex. Utilizing the Prey-Rank Model, we investigated whether dwindling encounter rates with high-rank prey prompted the Fremont's adoption of agriculture. We quantified past resource trends by analyzing the Utah archaeofaunal database to discern if ecological conditions influenced this transition. If confirmed, it suggests adaptive responses to a decline in high-ranked game led to a more resource-intensive survival strategy. This research provides crucial insights into the motivations behind the Fremont's agricultural adoption, enhancing our understanding of human-environment interactions and adaptations throughout history.

Cultivating Atmosphere In Independent Coffee Shops: Reflections On How Atmospheres Are Created Through Sensory Experiences, Brooke Bierhaus Sutton

Graduate Theses and Dissertations

Affective atmosphere is a fundamental component to the allure of coffee shops that is cultivated through sensory experience. In this thesis I examine how the sensory experience of sight, sound, smell, taste, and touch, create atmospheres in coffee shops. I ask, “how do coffee shops cultivate an affective atmosphere?” Through an exploration of material culture, design, affect, and the intentional production of third places, I illustrate the ways in which independent coffee shops have their own unique identities and atmospheres. By using memoir and reflexive analysis of my decade in global coffee culture, as well as an extensive literary review, …

Tour 3 Guidebook - From Farm To Kitchen: Rural, Indigenous, And Urban Places, Sarah F. Scarlett, Alison K. Hoagland, Hilary-Joy Virtanen

Vernacular Architecture Forum 2024 Annual Conference

Tour 3 guidebook from the 2024 Vernacular Architecture Forum Conference, North of the Northwoods: From Mines to Motels on Michigan's Lake Superior.

Consequences Of The Megafauna Extinction: Changes In Food Web Networks On The Edwards Plateau Across The Pleistocene–Holocene Transition, Quentin A. Smith Jr.

School of Biological Sciences: Dissertations, Theses, and Student Research

We are experiencing biodiversity loss due to climate change and human impacts, which is not only harmful to the environment but can also alter the composition of communities and interactions among species. The late Pleistocene experienced a loss of large-bodied mammals which resulted in significant changes in community structure due to changes in body size, diet, and species associations. The impact of these changes on species interactions and community structure across the Pleistocene-Holocene transition remains poorly understood. Using a robust data set of species composition, stable isotopes, body size, and climate variables, we constructed and compared ecological networks of mammal …

The Impact Of A Pgym Variant On Myophosphorylase Deficiency In Red Angus Composite Cattle And Changes In The Skeletal Muscle Transcriptome Due To The Intramuscular Administration Of Lidocaine In Wether Lambs, Mackenzie Christin Batt

School of Biological Sciences: Dissertations, Theses, and Student Research

Project 1 focused on eight calves in a Nebraska herd (composite Simmental, Red Angus, Gelbvieh) that displayed exercise intolerance during forced activity. Available sire pedigrees contained a paternal ancestor within 2-4 generations in all affected calves. Pedigrees of the calves’ dams were unavailable, however, the cows were ranch-raised and retained from prior breeding seasons, where bulls used for breeding occasionally had a common ancestor. Therefore, it was hypothesized that a de novo autosomal recessive variant was causative of exercise intolerance in these calves. A genome-wide association analysis followed by whole-genome sequencing led to the identification of a variant in the …

Ein Bericht Aus Einer Akademie: Writing About Germany's Lost Jewish Scholars, 80 Years On, J.G. Allen

Research Collection Yong Pung How School Of Law

This volume explores the life and work of F.A. Mann—a German-born and (mostly) German-educated jurist who spent the operative parts of his professional life in the United Kingdom (UK). The project on which the volume is based set out to understand Mann’s life as a lawyer and describe his legacy—in English law, and also in German, European, and international law.

Jacobs, Feygele, Kathryn Amend

Bronx Jewish History Project

Feygele Jacobs recounts her family's journey from Poland to the Bronx, detailing her parents' refugee experience post-World War II. Her parents initially settled in Newark, New Jersey, before moving to the Bronx. Feygele describes her education at PS 26 and Hunter College High School, involvement in Yiddish school and activities, and her parents' diverse backgrounds. Her mother, a late bloomer in education, pursued a career in social work after raising her children. The family moved to Co-Op City in 1972 due to neighborhood changes. Feygele highlights her parents' community involvement and her educational and career choices, including a brief stint …

Where Silicone Meets Silicon: Analyzing Nier: Automata As A Subversive Postfeminist Text With Respect To Marxism, Existentialism And Feminism, Joaquin Vela

Communication Honors Theses

No abstract provided.

Physiological Adaptations Following A Strength Endurance Training Block Performed With Accentuated Eccentric Loading Or Traditional Resistance Training, Alex Long

Electronic Theses and Dissertations

Physiological adaptations were investigated following a strength-endurance (S-E) block prescribed with accentuated eccentric loading (AEL) or traditional resistance training (TRAD). Recreationally trained participants (n = 11 males, 6 females, age = 23.2 ± 4.2 yrs, body mass (BM) = 81.3 ± 22.2 kg, height = 172.1 ± 10 cm) completed a four-week block of concurrent resistance, sprint, and change of direction training. Participants were assigned one of two training conditions, AEL (n = 9) or TRAD (n = 8). Training was identical, except AEL performed 110% eccentric overloading every 1^st, 3^rd, 5^th, 7^{th …}

P300 Event-Related Potential Responses To Self-Relevant Stimuli, Jordan Razzak

Electronic Theses and Dissertations

Previous literature has suggested an apparent P300 sensitivity to self-relevant stimuli. To further explore this relationship, we asked participants to submit 10 photos, each of a particular category (e.g. footwear, plants), to be used as either targets or distractors in a given condition of an oddball task. Furthermore, we attempted to see whether the effect of self-relevance on the P300 could be induced in a participant by allowing them to study a set of unique photos which would then be used as targets. Our analysis suggested that P300 amplitude elicited in response to self-relevant stimuli used as targets was statistically …

Exploring Available Information On The Gut-Brain Axis And Alzheimer’S Disease For Clinicians Making Dietary Recommendations: A Scoping Review, Megan Gibson

Electronic Theses and Dissertations

Abstract: Alzheimer’s Disease (AD) is a complex neurodegenerative disease that requires interprofessional collaboration. Pharmacological options are currently ineffective, increasing the need for preventative strategies to combat the rise of AD. Considerations of gut-targeted interventions have increased as a key component in the prevention of AD, based on the understanding that the state of the gut microbiome can impact cognitive function through the pathway known as the gut-brain axis.

Methods: This scoping review explored information on the gut-brain axis in persons with AD. A comprehensive search was conducted in November 2023. Forty reviews and 13 human studies were analyzed.

Results: There …

Beyond The Screen: Understanding College Students’ Perspectives On Cyberstalking, Gabrielle Jackson

Electronic Theses and Dissertations

Previous research regarding the victimization of college students is primarily geared toward physical or sexual encounters. There is a limited scope of research regarding the online victimization of college students, specifically those involved in Greek life organizations. Furthermore, there is a misinterpretation of the definition of cyberstalking among college students, as many students are unaware that they have been personally victimized (Cass, 2011). This study seeks to examine college students’ perceptions of online victimization and how they may vary. The different student impressions and the prevalence of online victimization were examined using self-reported data from students enrolled in a university …

Establishing “The Fossil Record”: A Database Of Vertebrate Paleontological Sites Across The State Of Tennessee, Sarah Mclaurine

Electronic Theses and Dissertations

Fossil localities across the state of Tennessee and the data related to those sites were compiled from Tennessee Division of Geology Bulletin 84, titled “Tennessee’s Prehistoric Vertebrates,” and stored in a Microsoft Access geodatabase housed by the Department of Collections at the East Tennessee State University Museum of Natural History located at the Gray Fossil Site. Included in the database are forms to enter new site localities, view information about those already entered, view and add data to a master faunal list for the state, view sites repository information and store and add documents that are key-word searchable from the …

Farm Chores For Life Skills: A Farm Based Therapy Program, Katelyn Murphy

Occupational Therapy Doctoral Capstones

The purpose of the doctoral capstone project is to advocate for farm-based therapy services through the development of an evidence-based farm-based therapy program.

What Is Biological Engineering? – A Magazine, Morgan Christensen

Undergraduate Honors Capstone Projects

Biological Engineering is one of the less commonly known fields of engineering and can be challenging to describe to someone outside the discipline. The most common question I've been asked during my undergraduate career is "What is biological engineering?". My answer has changed throughout my time at Utah State University as I've had more experiences within the discipline. This project focuses on answering this question in the format of a magazine to help bridge the gap between those in the discipline and a general audience. By using a magazine as the format, the content must be organized and written in …

Effects Of Humidity On Native And Non-Native Cavity Nesting Solitary Bees, Elleke Grace Kofford Manwill

Undergraduate Honors Capstone Projects

Invasive species are defined as those that are not native to an ecosystem but may cause harm to the environment or to human health. Osmia cornifrons, a species introduced to the United States, and Osmia lignaria, a native species, are cavity-nesting solitary bees. Although not officially classified as invasive, O. cornifrons presents competition for the niche that O. lignaria inhabits. O. cornifrons has established populations throughout the East Coast and the Pacific Northwest, while O. lignaria is found all throughout the contiguous United States. This interspecies difference in geographical range exists despite their similar temperature ranges. To determine …

Travels In Ireland, Melissa Evelyn Cook

Undergraduate Honors Capstone Projects

“Travels In Ireland” is a creative non-fiction essay with elements of travel writing. It follows my journey around Ireland, including Killarney, Dingle, Kell’s Bay, Castle Desmond, Galway, the Aran Islands and Coole Park. This essay is in communication with other travel writing pieces as I experiment with the genre. In preparation I read many different examples of travel writing including Travels with Charley, Stones of Aran, and On the Shoreline of Knowledge. My initial plan for this project involved studying cultural differences and experimenting with the genre of travel writing. While I began this project without a …

How Variation In Activity Time And Duration At Water Sources Affects Feral Horse Vulnerability To Cougar Predation In Southern Nevada, Katelyn Davies

Undergraduate Honors Capstone Projects

Feral horses have become prominent in the Intermountain West. Approximately 43,000 horses are found in Nevada alone. With increasing numbers, they have become a large portion of ungulate biomass. Thus, it is important to understand their behavior, as they become integrated into western wildlife communities. However, little research has been conducted on the ecology of feral horses, and their relationships with native ungulates, carnivores, and local resources such as water.

To address these concerns, I outlined three objectives: (1) determine if horses changed their water visitation activity times in relation to temperature. As a primarily diurnal species, we were interested …

It Started On A Stage, Jordan Lockwood

Undergraduate Honors Capstone Projects

The creation of It Started On A Stage aimed to answer if any amount of experience with theater can affect an individual. The show is a devised piece inspired by a series of interviews with 15 subjects. Devised theater is a branch of applied theater where individuals collaborate on creating the script. The interviewees all had varying levels of experience in differing fields of expertise. I asked them a series of questions regarding their past and current experiences with theater. Regardless of their level of involvement or whether they were currently pursuing it, all of these participants agreed that theater …

An Exploratory Case Study Of Students’ Blended Learning Experiences During Post Emergency Learning, Heidy M. Garcia Moreno

Theses and Dissertations

The COVID-19 pandemic has accelerated the integration of technology in classrooms. This has highlighted the need for a deeper understanding of how students experience these learning environments. In response, this case study explored how students experience blended learning in post emergency learning through a digital equity lens. The analysis of interview data revealed six major themes, which yielded three key findings. These findings emphasize the need to embrace a simplified approach to technology integration, refine instructional practices to effectively use technology as a supplement rather than a replacement for traditional tactile elements, while also advancing digital literacy that builds high …

‘Samoye Vazhnoye’: Behind The Scenes Of Russian Cinema, 1908–1924, Katerina Ludwig

War, Diplomacy, and Society (MA) Theses

From the first decade of the 20^th century to the middle of the 1920s, cinema in Russia exposed how politics and the modern medium were inseparably intertwined. As works that were produced during a period of great turmoil and uncertainty, films revealed more than a unilateral relationship. Cinema was used in Russia in the late-Imperial and early Soviet eras as an active tool of entertainment, propaganda, art, education, and intellectual discussion. Studying its intersectional nature illuminates areas obscured by purely political or artistic perspectives, which tell either opposite or mutually emboldening tales. This thesis argues on behalf of both …

Vmed 531: Introduction To Animal Welfare A Faculty-Led Inquiry Into Reflective Scholarly Teaching Benchmark Portfolio, Amy Walton

UNL Faculty Course Portfolios

This benchmark portfolio documents course design, student learning, and reflection of teaching methods for VMED 531 Introduction to Animal Welfare. This one credit hour course provides an overview of animal welfare topics and assessment through a veterinary medical lens. Participants are first year veterinary students that have been accepted into Professional Program of Veterinary Medicine (PPVM). This course creates a foundational knowledge base regarding animal welfare topics and fosters critical thinking with how veterinary treatments, surgeries, and animal-use practices influence animal welfare. The ability to utilize critical thinking skills and science-based evidence to create a sound solution is essential regarding …

2024 May, Morehead State University. Office Of Communications & Marketing.

Morehead State Press Release Archive, 1961 to the Present

Press releases for May of 2024.

Ictal Central Apnea Is Predictive Of Mesial Temporal Seizure Onset: An Intracranial Investigation, Nuria Lacuey, Blanca Talavera, Oman Magana-Tellez, Oscar Mancera-Páez, Norma Hupp, Xi Luo, Johnson P Hampson, Jaison Hampson, M R Sandhya Rani, Manuela Ochoa-Urrea, Omar A Alamoudi, Stephen Melius, Sandipan Pati, Jay Gavvala, Nitin Tandon, John C Mosher, Samden D Lhatoo

Faculty, Staff and Student Publications

Objective: Ictal central apnea (ICA) is a semiological sign of focal epilepsy, associated with temporal and frontal lobe seizures. In this study, using qualitative and quantitative approaches, we aimed to assess the localizational value of ICA. We also aimed to compare ICA clinical utility in relation to other seizure semiological features of focal epilepsy.

Methods: We analyzed seizures in patients with medically refractory focal epilepsy undergoing intracranial stereotactic electroencephalographic (SEEG) evaluations with simultaneous multimodal cardiorespiratory monitoring. A total of 179 seizures in 72 patients with reliable artifact-free respiratory signal were analyzed.

Results: ICA was seen in 55 of 179 (30.7%) …

Endo/Exo, Delaney Rogers

Electronic Theses and Dissertations

The artist, Delaney Shae Rogers, discusses her Master of Fine Arts exhibition, Endo / Exo, held at the Tipton Gallery in downtown Johnson City, TN. The exhibition dates are from March 25th through April 5th, 2024, with a public reception held April 5th, 2024. The author provides insight into the concept behind the work in the exhibition and shares how the making process and specific materials impact the work. This body of work explores coping with grief, anxiety, and the state of the world through the process of making and communicating otherwise difficult topics through visually digestible symbolic language.