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Who Helps Tsimane Children And Adults?, Eric Schniter, Daniel K. Cummings, Paul L. Hooper, Jonathan Stieglitz, Benjamin C. Trumble, Hillard S. Kaplan, Michael D. Gurven Jun 2024

Who Helps Tsimane Children And Adults?, Eric Schniter, Daniel K. Cummings, Paul L. Hooper, Jonathan Stieglitz, Benjamin C. Trumble, Hillard S. Kaplan, Michael D. Gurven

ESI Working Papers

We examine various forms of helping behavior among Tsimane Amerindians of Bolivia, focusing on the provision of shelter, childcare, food, sickcare, cultural influence, and traditional story knowledge. Kin selection theory traditionally explains nepotistic nurturing of youth by closely related kin. However, less attention has been given to understanding the help provided by individuals without close genetic relatedness. To explain who provides various forms of help, we evaluate support for several predictions derived from kin selection theory. Our results show that helpers who are most often closely related and from an older generation tend to provide more costly forms of help …


The Crosstalk Between Amyloid-Β, Retina, And Sleep For The Early Diagnosis Of Alzheimer's Disease: A Narrative Review, Isaiah Lorenzo De Guia, Shaun Eslick, Sharon L. Naismith, Swathi Kanduri, Tejal M. Shah, Ralph N. Martins Jun 2024

The Crosstalk Between Amyloid-Β, Retina, And Sleep For The Early Diagnosis Of Alzheimer's Disease: A Narrative Review, Isaiah Lorenzo De Guia, Shaun Eslick, Sharon L. Naismith, Swathi Kanduri, Tejal M. Shah, Ralph N. Martins

Research outputs 2022 to 2026

Alzheimer's disease (AD) is the most common type of dementia, which is characterised by progressive memory loss and accumulation of hallmark markers amyloid-β (Aβ) and neurofibrillary tangles in the diseased brain. The current gold standard diagnostic methods have limitations of being invasive, costly, and not easily accessible. Thus, there is a need for new avenues, such as imaging the retina for early AD diagnosis. Sleep disruption is symptomatically frequent across preclinical and AD subjects. As circadian activity, such as the sleep-wake cycle, is linked to the retina, analysis of their association may be useful additions for achieving predictive AD diagnosis. …


Country-Level Primary-Final-Useful (Cl-Pfu) And World Long-Run (Wlr-Pfu) Energy And Exergy Databases, Matthew Kuperus Heun Jun 2024

Country-Level Primary-Final-Useful (Cl-Pfu) And World Long-Run (Wlr-Pfu) Energy And Exergy Databases, Matthew Kuperus Heun

University Faculty Publications and Creative Works

No abstract provided.


Benefits Of Plant Pigment, Quercetin, For Fish And Prawn, Yos Adi Prakoso, Jasir Hakim Hidayah, Michael Richard Sanjaya, Agga Dhigayuka Pratama, Annisha Permata Nurul Azhar, Arya Surya Kuswanto, Berlian Ronaldi April, Intan Karisma Utami, Mahera Sandi Sasmita Putra, Maria Paulina Wukak, Naufal Farros Satria Jun 2024

Benefits Of Plant Pigment, Quercetin, For Fish And Prawn, Yos Adi Prakoso, Jasir Hakim Hidayah, Michael Richard Sanjaya, Agga Dhigayuka Pratama, Annisha Permata Nurul Azhar, Arya Surya Kuswanto, Berlian Ronaldi April, Intan Karisma Utami, Mahera Sandi Sasmita Putra, Maria Paulina Wukak, Naufal Farros Satria

Makara Journal of Science

Quercetin is an important phytochemical that belongs to the flavonoid group of plant pigments. It has potential benefits as an antioxidant, antiviral, and anti-inflammatory agent. However, the utilization of quercetin in aquaculture is not optimal. Hence, this study conducted a literature review to analyze the potential benefits of quercetin in aquaculture, especially for fish and prawn. Results showed that quercetin can be isolated from herbs using several methods, including sonication, maceration, and fractionation. Its amount in plants can be potentially determined using high-performance liquid chromatography and thin-layer chromatography. Some of the plants containing high quercetin levels include shallot, garlic, apple …


Hypoxia Inducible Factor 2Α Promotes Tolerogenic Macrophage Development During Cardiac Transplantation Through Transcriptional Regulation Of Colony Stimulating Factor 1 Receptor, Matthew Deberge, Samantha Schroth, Fanfan Du, Xin Yi Yeap, Jiao-Jing Wang, Zheng Jenny Zhang, Mohammed Javeed Ansari, Evan A Scott, Edward B Thorp Jun 2024

Hypoxia Inducible Factor 2Α Promotes Tolerogenic Macrophage Development During Cardiac Transplantation Through Transcriptional Regulation Of Colony Stimulating Factor 1 Receptor, Matthew Deberge, Samantha Schroth, Fanfan Du, Xin Yi Yeap, Jiao-Jing Wang, Zheng Jenny Zhang, Mohammed Javeed Ansari, Evan A Scott, Edward B Thorp

Faculty, Staff and Student Publications

Solid organ transplantation mobilizes myeloid cells, including monocytes and macrophages, which are central protagonists of allograft rejection. However, myeloid cells can also be functionally reprogrammed by perioperative costimulatory blockade to promote a state of transplantation tolerance. Transplantation tolerance holds promise to reduce complications from chronic immunosuppression and promote long-term survival in transplant recipients. We sought to identify different mediators of transplantation tolerance by performing single-cell RNA sequencing of acute rejecting or tolerized cardiac allografts. This led to the unbiased identification of the transcription factor, hypoxia inducible factor (HIF)-2α, in a subset of tolerogenic monocytes. Using flow cytometric analyses and mice …


Cracd Loss Induces Neuroendocrine Cell Plasticity Of Lung Adenocarcinoma, Bongjun Kim, Shengzhe Zhang, Yuanjian Huang, Kyung-Pil Ko, Youn-Sang Jung, Jinho Jang, Gengyi Zou, Jie Zhang, Sohee Jun, Kee-Beom Kim, Kwon-Sik Park, Jae-Il Park Jun 2024

Cracd Loss Induces Neuroendocrine Cell Plasticity Of Lung Adenocarcinoma, Bongjun Kim, Shengzhe Zhang, Yuanjian Huang, Kyung-Pil Ko, Youn-Sang Jung, Jinho Jang, Gengyi Zou, Jie Zhang, Sohee Jun, Kee-Beom Kim, Kwon-Sik Park, Jae-Il Park

Faculty, Staff and Student Publications

Tumor cell plasticity contributes to intratumoral heterogeneity and therapy resistance. Through cell plasticity, some lung adenocarcinoma (LUAD) cells transform into neuroendocrine (NE) tumor cells. However, the mechanisms of NE cell plasticity remain unclear. CRACD (capping protein inhibiting regulator of actin dynamics), a capping protein inhibitor, is frequently inactivated in cancers. CRACD knockout (KO) is sufficient to de-repress NE-related gene expression in the pulmonary epithelium and LUAD cells. In LUAD mouse models, Cracd KO increases intratumoral heterogeneity with NE gene expression. Single-cell transcriptomic analysis showed that Cracd KO-induced NE cell plasticity is associated with cell de-differentiation and stemness-related pathway activation. The …


Plum Curculio (Conotrachelus Nenuphar), Kate V. Richardson, Marion Murray Jun 2024

Plum Curculio (Conotrachelus Nenuphar), Kate V. Richardson, Marion Murray

All Current Publications

Plum curculio is a brown weevil (beetle with a snout) native to eastern North America, where it is a major pest of pome and stone fruits. It was detected in Box Elder County, Utah, in the early 1980s, and this population remains the only known infestation in western North America, where it is occasionally found in residential and wild fruit trees. Plum curculio is a quarantine pest in western North America (U.S. and Canada), and fruit grown in infested counties is restricted from being exported. Thus, it is a threat to Utah’s fruit industry and requires ongoing monitoring and management …


Reflections On Zooarchaeology In East Polynesia: Human-Animal Interactions And Human Ecodynamics, Virginia L. Butler Jun 2024

Reflections On Zooarchaeology In East Polynesia: Human-Animal Interactions And Human Ecodynamics, Virginia L. Butler

Anthropology Faculty Publications and Presentations

The essay summarizes the key pillars of human ecodynamics (HE) research and then highlights the most trenchant ideas from each of the seven papers in the Special Issue, especially as they intersect with HE.


Airy-Beam Holographic Sonogenetics For Advancing Neuromodulation Precision And Flexibility, Zhongtao Hu, Yaoheng Yang, Leqi Yang, Yan Gong, Chinwendu Chukwu, Dezhuang Ye, Yimei Yue, Jinyun Yuan, Alexxai V Kravitz, Hong Chen Jun 2024

Airy-Beam Holographic Sonogenetics For Advancing Neuromodulation Precision And Flexibility, Zhongtao Hu, Yaoheng Yang, Leqi Yang, Yan Gong, Chinwendu Chukwu, Dezhuang Ye, Yimei Yue, Jinyun Yuan, Alexxai V Kravitz, Hong Chen

2020-Current year OA Pubs

Advancing our understanding of brain function and developing treatments for neurological diseases hinge on the ability to modulate neuronal groups in specific brain areas without invasive techniques. Here, we introduce Airy-beam holographic sonogenetics (AhSonogenetics) as an implant-free, cell type-specific, spatially precise, and flexible neuromodulation approach in freely moving mice. AhSonogenetics utilizes wearable ultrasound devices manufactured using 3D-printed Airy-beam holographic metasurfaces. These devices are designed to manipulate neurons genetically engineered to express ultrasound-sensitive ion channels, enabling precise modulation of specific neuronal populations. By dynamically steering the focus of Airy beams through ultrasound frequency tuning, AhSonogenetics is capable of modulating neuronal populations …


Dorsal Raphe Neurons Integrate The Values Of Reward Amount, Delay, And Uncertainty In Multi-Attribute Decision-Making, Yang-Yang Feng, Ethan S Bromberg-Martin, Ilya E Monosov Jun 2024

Dorsal Raphe Neurons Integrate The Values Of Reward Amount, Delay, And Uncertainty In Multi-Attribute Decision-Making, Yang-Yang Feng, Ethan S Bromberg-Martin, Ilya E Monosov

2020-Current year OA Pubs

The dorsal raphe nucleus (DRN) is implicated in psychiatric disorders that feature impaired sensitivity to reward amount, impulsivity when facing reward delays, and risk-seeking when confronting reward uncertainty. However, it has been unclear whether and how DRN neurons signal reward amount, reward delay, and reward uncertainty during multi-attribute value-based decision-making, where subjects consider these attributes to make a choice. We recorded DRN neurons as monkeys chose between offers whose attributes, namely expected reward amount, reward delay, and reward uncertainty, varied independently. Many DRN neurons signaled offer attributes, and this population tended to integrate the attributes in a manner that reflected …


Role Of The Afferent Lymph As An Immunological Conduit To Analyze Tissue Antigenic And Inflammatory Load, Padma P Nanaware, Cheryl F Lichti, Xiaoxiao Wan, Emil R Unanue, Et Al. Jun 2024

Role Of The Afferent Lymph As An Immunological Conduit To Analyze Tissue Antigenic And Inflammatory Load, Padma P Nanaware, Cheryl F Lichti, Xiaoxiao Wan, Emil R Unanue, Et Al.

2020-Current year OA Pubs

The lymphatic fluid is the conduit by which part of the tissue "omics" is transported to the draining lymph node for immunosurveillance. Following cannulation of the pre-nodal cervical and mesenteric afferent lymphatics, herein we investigate the lymph proteomic composition, uncovering that its composition varies according to the tissue of origin. Tissue specificity is also reflected in the dendritic cell-major histocompatibility complex class II-eluted immunopeptidome harvested from the cervical and mesenteric nodes. Following inflammatory disruption of the gut barrier, the lymph antigenic and inflammatory loads are analyzed in both mice and subjects with inflammatory bowel diseases. Gastrointestinal tissue damage reflects the …


Injury-Induced Foxm1 Expression In The Mouse Kidney Drives Epithelial Proliferation By A Cyclin F-Dependent Mechanism, Megan L. Noonan, Yoshiharu Muto, Yasuhiro Yoshimura, Aidan Leckie-Harre, Haojia Wu, Vladimir V. Kalinichenko, Benjamin D. Humphreys, Monica Chang-Panesso Jun 2024

Injury-Induced Foxm1 Expression In The Mouse Kidney Drives Epithelial Proliferation By A Cyclin F-Dependent Mechanism, Megan L. Noonan, Yoshiharu Muto, Yasuhiro Yoshimura, Aidan Leckie-Harre, Haojia Wu, Vladimir V. Kalinichenko, Benjamin D. Humphreys, Monica Chang-Panesso

2020-Current year OA Pubs

Acute kidney injury (AKI) strongly upregulates the transcription factor Foxm1 in the proximal tubule in vivo, and Foxm1 drives epithelial proliferation in vitro. Here, we report that deletion of Foxm1 either with a nephron-specific Cre driver or by inducible global deletion reduced proximal tubule proliferation after ischemic injury in vivo. Foxm1 deletion led to increased AKI to chronic kidney disease transition, with enhanced fibrosis and ongoing tubule injury 6 weeks after injury. We report ERK mediated FOXM1 induction downstream of the EGFR in primary proximal tubule cells. We defined FOXM1 genomic binding sites by cleavage under targets and release using …


An Interview With Scott Thigpen: Graphic Designer, Sarah Burch Jun 2024

An Interview With Scott Thigpen: Graphic Designer, Sarah Burch

Memorandum (student professional writing magazine)

No abstract provided.


Prolific Phalluses - Male Figural Art Of The Colima: An Examination Of The Presence And Meaning Behind The Representation Of The Phallus In Colima Art, Griffin Nordstrom Jun 2024

Prolific Phalluses - Male Figural Art Of The Colima: An Examination Of The Presence And Meaning Behind The Representation Of The Phallus In Colima Art, Griffin Nordstrom

Clio: WVU Art History Research Journal

No abstract provided.


Full Issue Jun 2024

Full Issue

Clio: WVU Art History Research Journal

No abstract provided.


Online Writing Resources For Pw & Rc Students, Sarah Stasiak Jun 2024

Online Writing Resources For Pw & Rc Students, Sarah Stasiak

Memorandum (student professional writing magazine)

No abstract provided.


Memorandum 1.1 (Complete Issue), Memorandum Staff Jun 2024

Memorandum 1.1 (Complete Issue), Memorandum Staff

Memorandum (student professional writing magazine)

No abstract provided.


Around The Center, 2000 April/May, Advocate Health - Midwest Jun 2024

Around The Center, 2000 April/May, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and a feature on the upcoming merger with Advocate Health Care.


Storage And Interaction Diagrams: Extending The Diagrammatic Framework Of Kinetic And Free-Body Diagrams To Other Conservation And Accounting Principles, Amir H. Danesh-Yazdi Jun 2024

Storage And Interaction Diagrams: Extending The Diagrammatic Framework Of Kinetic And Free-Body Diagrams To Other Conservation And Accounting Principles, Amir H. Danesh-Yazdi

Faculty Publications - Mechanical Engineering

After defining a system for analysis, a rigorous process is taught to students in their Statics and Dynamics courses on how to draw proper kinetic, free-body, and impulse-momentum diagrams. While numerous techniques and mnemonics have been mentioned in literature, any experienced instructor can tell a correct free-body diagram apart from an incorrect one. Unfortunately, this is not the case when considering scalar properties such as mass, energy, exergy, and entropy. Different fluid mechanics and thermodynamics texts have treated the diagrammatic representation of these properties either very poorly, or in the case of the latter two, not at all. In this …


Workflow: Using A Python Script To Capture And Summarize Instagram Feeds At Rauner Special Collections, Muhammad Moiz Jun 2024

Workflow: Using A Python Script To Capture And Summarize Instagram Feeds At Rauner Special Collections, Muhammad Moiz

Rauner Special Collections Digital Archives Practice

This public workflow contains a python script that will summarize and capture Instagram feeds. The script will capture the original digital assets and also create a PDF that summarizes and describes each post of the feed while capturing a digital image of the Instagram post. The python code will run in a Windows or MAC environment. Any archive may modify the script to suit their needs, provided that they have a code editor and python installed. This particular version of the script is designed to prepare uploads to Preservica using Preservica’s bulk incremental “opex” ingest – the files will then …


Table Of Contents Jun 2024

Table Of Contents

Public Land & Resources Law Review

No abstract provided.


Letter To The Reader Jun 2024

Letter To The Reader

Public Land & Resources Law Review

No abstract provided.


The Public Trust Doctrine And Wildlife Management In Montana: A Primer, Martin Nie Jun 2024

The Public Trust Doctrine And Wildlife Management In Montana: A Primer, Martin Nie

Public Land & Resources Law Review

No abstract provided.


Co-Stewardship In Practice: Yellowstone Bison, Patrick J. White Jun 2024

Co-Stewardship In Practice: Yellowstone Bison, Patrick J. White

Public Land & Resources Law Review

No abstract provided.


Nnalsa Briefs Introduction Jun 2024

Nnalsa Briefs Introduction

Public Land & Resources Law Review

No abstract provided.


Exemplary Brief For Petitioner, Eames Armstrong, E. C. Bell Jun 2024

Exemplary Brief For Petitioner, Eames Armstrong, E. C. Bell

Public Land & Resources Law Review

No abstract provided.


Exemplary Brief For Respondent, Skylee James, Lauren Bretz Jun 2024

Exemplary Brief For Respondent, Skylee James, Lauren Bretz

Public Land & Resources Law Review

No abstract provided.


Time And Habitat Structure Shape Insect Acoustic Activity In The Amazon, Leandro A. Do Nascimento, Cristian Pérez-Granados, Janderson B. Rodrigues Alencar, Karen H. Beard Jun 2024

Time And Habitat Structure Shape Insect Acoustic Activity In The Amazon, Leandro A. Do Nascimento, Cristian Pérez-Granados, Janderson B. Rodrigues Alencar, Karen H. Beard

Wildland Resources Faculty Publications

Insects are the most diverse animal taxon on Earth and play a key role in ecosystem functioning. However, they are often neglected by ecological surveys owing to the difficulties involved in monitoring this small and hyper-diverse taxon. With technological advances in biomonitoring and analytical methods, these shortcomings may finally be addressed. Here, we performed passive acoustic monitoring at 141 sites (eight habitats) to investigate insect acoustic activity in the Viruá National Park, Brazil. We first describe the frequency range occupied by three soniferous insect groups (cicadas, crickets and katydids) to calculate the acoustic evenness index (AEI). Then, we assess how …


Ephrin-B2 Promotes Nociceptive Plasticity And Hyperalgesic Priming Through Ephb2-Mnk-Eif4e Signaling In Both Mice And Humans, Eric David, Muhammad Saad Yousuf, Hao-Ruei Mei, Ashita Jain, Sharada Krishnagiri, Hajira Elahi, Rupali Venkatesan, Kolluru Srikanth, Gregory Dussor, Matthew Dalva, Theodore Price Jun 2024

Ephrin-B2 Promotes Nociceptive Plasticity And Hyperalgesic Priming Through Ephb2-Mnk-Eif4e Signaling In Both Mice And Humans, Eric David, Muhammad Saad Yousuf, Hao-Ruei Mei, Ashita Jain, Sharada Krishnagiri, Hajira Elahi, Rupali Venkatesan, Kolluru Srikanth, Gregory Dussor, Matthew Dalva, Theodore Price

Department of Neuroscience Faculty Papers

Ephrin-B-EphB signaling can promote pain through ligand-receptor interactions between peripheral cells, like immune cells expressing ephrin-Bs, and EphB receptors expressed by DRG neurons. Previous studies have shown increased ephrin-B2 expression in peripheral tissues like synovium of rheumatoid and osteoarthritis patients, indicating the clinical significance of this signaling. The primary goal of this study was to understand how ephrin-B2 acts on mouse and human DRG neurons, which express EphB receptors, to promote pain and nociceptor plasticity. We hypothesized that ephrin-B2 would promote nociceptor plasticity and hyperalgesic priming through MNK-eIF4E signaling, a critical mechanism for nociceptive plasticity induced by growth factors, cytokines …


Russian Verbs Of Motion: Analyzing Pedagogical Approaches And Developing A Handbook For Russian Language Learners, Elena Petrova Jun 2024

Russian Verbs Of Motion: Analyzing Pedagogical Approaches And Developing A Handbook For Russian Language Learners, Elena Petrova

Theses and Dissertations

Motion is an indispensable part of human life, and it is important to be able to talk about motion verbally. However, different languages encode motion differently, and, therefore, the acquisition of this aspect can be challenging. It can be especially difficult for English-speaking Russian language learners because Russian Verbs of Motion function differently from those in the English language. Verbs of Motion in Russian include eight basic verb pairs based on the directionality of movement, e.g. идти/ходить (to go). The study analyzes four pedagogical materials on Verbs of Motion and explores how authors present this topic to Russian language learners. …