Digital Commons Network^™

Pins, Inhwan Jeon

Theses

Pins aims to portray the societal landscape observed and experienced by me as an international student, highlighting sociological concerns like hatred and hate crimes instead of focusing on surface-level metrics such as the risk and fatality rates of COVID-19. Through this work, I want to remind the audience of the multifaceted nature of society and the emotions evoked by COVID-19, prompting reflection on the role of art during times of crisis. While transforming my original medium of metal objects into an installation art format, I explored concepts such as spacing, installation, cognition, narrative, and multiple senses. I integrated these elements …

Potential Targeting Mechanisms For Bone-Directed Therapies, Betul Celik, Andrés Leal, Shunji Tomatsu

Department of Pediatrics Faculty Papers

Bone development is characterized by complex regulation mechanisms, including signal transduction and transcription factor-related pathways, glycobiological processes, cellular interactions, transportation mechanisms, and, importantly, chemical formation resulting from hydroxyapatite. Any abnormal regulation in the bone development processes causes skeletal system-related problems. To some extent, the avascularity of cartilage and bone makes drug delivery more challenging than that of soft tissues. Recent studies have implemented many novel bone-targeting approaches to overcome drawbacks. However, none of these strategies fully corrects skeletal dysfunction, particularly in growth plate-related ones. Although direct recombinant enzymes (e.g., Vimizim for Morquio, Cerezyme for Gaucher, Elaprase for Hunter, Mepsevii for …

Functional & Evolutionary Analysis Of Tbx2a And Tbx2b In Zebrafish Heart Development, Maliha Tasnim

Theses and Dissertations

Congenital Heart Disease (CHD) is the most common birth defect, affecting approximately 1% of live births. This dissertation explores the genetic mechanisms underlying CHD, focusing on the T-box transcription factors Tbx2a and Tbx2b in zebrafish. Utilizing advanced bioinformatics techniques, we reconstructed the ancestral sequences of these genes to understand their evolutionary trajectory and functional divergence. Our analysis highlights the evolutionary conservation of the DNA-binding domain in tbx2a and tbx2b, suggesting its crucial role in maintaining correct gene expression patterns during development. We observed unique and shared amino acid substitutions in these proteins, indicating potential adaptive changes and conserved functions. Comparative …

The Role Of Sensing Modalities In Shaping Collective Motion And Group Behavior, Poorendra P. Ramlall

Doctoral Dissertations and Master's Theses

Collective behavior refers to the coordinated movements that emerge from simple interactions between individuals within a group. Traditionally, researchers have modeled these interactions assuming individuals can sense their surroundings in all directions, like having eyes all around their heads. While this is a useful simplification, it does not capture the diverse ways animals actually sense the world. In this thesis, we take inspiration from the natural world, particularly from animals like bats and dolphins that use a combination of hearing and sight to navigate their environments. We explore how combining these sensory cues in a three-dimensional space affects the way …

Cherokia Georgiana Mitogenome Sequencing And Analysis, William Wittstock

Biology Theses

Despite the vast diversity of millipedes, complete genomic and mitogenomic data available in public databases is limited, hindering comprehensive studies on their classification, evolution, and genetics. Among the underrepresented taxa are the Xystodesmidae, a family comprising approximately 500 species with minimal mitogenomic data, and no complete genomes sequenced. Our research involves sequencing the mitochondrial genome of Cherokia georgiana, a representative of this diverse family with interesting traits that are not clearly defined at a genetic level. This research also serves as a pilot study to develop DNA extraction methods and protocols for whole genome sequencing. Multiple DNA extraction kits …

Grievability And The Contingency Of Life Value In Twenty-First-Century Science Fiction, Emily A. Reiff

English Language and Literature ETDs

Using Judith Butler’s framework of grievability, this dissertation explores twenty-first-century science fiction by British, Irish, and Caribbean authors whose novels grapple with legacies of colonialism and imperialism that relied on dehumanization and subjugation. Beginning with Sarah Maria Griffin’s Spare and Found Parts (2016), chapter one explores neocolonial rationales—purportedly based on health—which recreate colonial divisions of class and labor and enforce systems of diminishing grievability in a post-apocalyptic Irish context. Chapter two contends that Kazuo Ishiguro’s Klara and the Sun (2021) illustrates the danger inherent to value systems that center “normative” embodiment in worlds that reconfigure hypercapacitated human beings as the …

Gabaa Receptor Subunit Composition Regulates Circadian Rhythms In Rest–Wake And Synchrony Among Cells In The Suprachiasmatic Nucleus, Daniel Granados-Fuentes, Peter Lambert, Tatiana Simon, Steven Mennerick, Erik D Herzog

2020-Current year OA Pubs

The mammalian circadian clock located in the suprachiasmatic nucleus (SCN) produces robust daily rhythms including rest-wake. SCN neurons synthesize and respond to γ-aminobutyric acid (GABA), but its role remains unresolved. We tested the hypothesis that γ2- and δ-subunits of the GABA

Treatment Response With Potassium-Competitive Acid Blockers Based On Clinical Phenotypes Of Gastroesophageal Reflux Disease: A Systematic Literature Review And Meta-Analysis, Seungyeon Seo, Hye-Kyung Jung, C Prakash Gyawali, Hye Ah Lee, Hyung Seok Lim, Eui Sun Jeong, Seong Eun Kim, Chang Mo Moon

2020-Current year OA Pubs

BACKGROUND/AIMS: Gastroesophageal reflux disease (GERD) is typically managed based on the clinical phenotype. We evaluated the efficacy and safety of potassium-competitive acid blockers (PCABs) in patients with various clinical GERD phenotypes.

METHODS: Core databases were searched for studies comparing PCABs and proton pump inhibitors (PPIs) in clinical GERD phenotypes of erosive reflux disease (ERD), non-erosive reflux disease (NERD), PPI-resistant GERD and night-time heartburn. Additional analysis was performed based on disease severity and drug dosage, and pooled efficacy was calculated.

RESULTS: In 9 randomized controlled trials (RCTs) evaluating the initial treatment of ERD, the risk ratio for healing with PCABs versus …

Uncertain Future Dwelling: Emergent Interiors Of The Metaverse, Belinda J. Dunstan, Michael Stonham, Demet Dincer

Interiority

Contemporarily, a flood of digital interior architectural imagery has emerged of spaces developed for the Metaverse, a forthcoming immersive 3D virtual world. These spaces are not bound by the conventions of architectural practice nor the demands of the physical world, providing an opportunity for design exploration and innovation in the future of interiors and positing challenges to core architectural concepts that have accompanied traditional practice. This research offers a visual analysis of aesthetic trends and new typologies present in the interior architectural spaces designed for the Metaverse. The analysis features a curated and collaged collection of works from ten creators …

Exploring The Pdz, Duf, And Lim Domains Of Pdlim5 In Dendrite Branching, Yogesh Srivastava, Maxsam Donta, Lydia L Mireles, Adriana Paulucci-Holthauzen, Leilei Shi, Mark T Bedford, M Neal Waxham, Pierre D Mccrea

Faculty, Staff and Student Publications

The branched architecture of neuronal dendrites is a key factor in how neurons form ordered networks and discoveries continue to be made identifying proteins and protein-protein interactions that direct or execute the branching and extension of dendrites. Our prior work showed that the molecular scaffold Pdlim5 and delta-catenin, in conjunction, are two proteins that help regulate the branching and elongation of dendrites in cultured hippocampal neurons and do so through a phosphorylation-dependent mechanism triggered by upstream glutamate signaling. In this report we have focused on Pdlim5's multiple scaffolding domains and how each contributes to dendrite branching. The three identified regions …

The Interaction Of Endorepellin And Neurexin Triggers Neuroepithelial Autophagy And Maintains Neural Tube Development, Lei Lu, Meizhu Bai, Yufang Zheng, Xiukun Wang, Zhongzhong Chen, Rui Peng, Richard H Finnell, Tongjin Zhao, Chengtao Li, Bo Wu, Yunping Lei, Jinsong Li, Hongyan Wang

Faculty, Staff and Students Publications

Heparan sulfate proteoglycan 2 (HSPG2) gene encodes the matrix protein Perlecan, and genetic inactivation of this gene creates mice that are embryonic lethal with severe neural tube defects (NTDs). We discovered rare genetic variants of HSPG2 in 10% cases compared to only 4% in controls among a cohort of 369 NTDs. Endorepellin, a peptide cleaved from the domain V of Perlecan, is known to promote angiogenesis and autophagy in endothelial cells. The roles of enderepellin in neurodevelopment remain unclear so far. Our study revealed that endorepellin can migrate to the neuroepithelial cells and then be recognized and bind with the …

Pocket Gophers, Mark Nelson, S. Nicole Frey, Earl Creech, Kalen Taylor, Jacob Hadfield, Linden Greenhalgh, Cory Farnsworth, Jody Gale, Melanie Heaton, Justin Wyatt Clawson, Steve Price

All Current Publications

Pocket gophers can damage agriculture and human development infrastructure. In agricultural fields, pocket gophers cause conflicts by directly consuming plants, destroying plants when their soil mounds cover them, and causing premature loss of field stands such as alfalfa, necessitating expensive alfalfa stand replacement. They can chew through electrical, internet, and other utility cables, damaging irrigation pipes, and compromising the integrity of canals and ditch banks. They also cause significant damage to lawns and gardens in urban areas. Understanding pocket gopher habits, especially the burrow system, is the key to effective control. Management methods include trapping, hand or mechanical baiting, fumigation, …

The Isr Downstream Target Atf4 Represses Long-Term Memory In A Cell Type-Specific Manner, Niaz Mahmood, Jung-Hyun Choi, Pei You Wu, Sean W Dooling, Trent A Watkins, Ziying Huang, Jesse Lipman, Hanjie Zhao, Anqi Yang, Jake Silversmith, Yanis Inglebert, Constantinos Koumenis, Vijendra Sharma, Jean-Claude Lacaille, Wayne S Sossin, Arkady Khoutorsky, R Anne Mckinney, Mauro Costa-Mattioli, Nahum Sonenberg

Faculty, Staff and Students Publications

The integrated stress response (ISR), a pivotal protein homeostasis network, plays a critical role in the formation of long-term memory (LTM). The precise mechanism by which the ISR controls LTM is not well understood. Here, we report insights into how the ISR modulates the mnemonic process by using targeted deletion of the activating transcription factor 4 (ATF4), a key downstream effector of the ISR, in various neuronal and non-neuronal cell types. We found that the removal of ATF4 from forebrain excitatory neurons (but not from inhibitory neurons, cholinergic neurons, or astrocytes) enhances LTM formation. Furthermore, the deletion of ATF4 in …

Thermal Oxidative Degradation Of Polystyrene Plastics Used For Food Packaging During Incomplete Waste Incineration, Maycee Hurd

Civil Engineering ETDs

We identified the physical and chemical degradation of polystyrene (PS) plastic used for food packaging after thermal oxidative weathering. Open waste incineration is a widely used waste management practice in isolated and underserved communities. However, the generation of partially incinerated plastics and microplastics (MPs) from this practice is overlooked. Near surface XPS C 1s high resolution analyses show an increase in the intensity of peaks greater than 285 eV corresponding to C/O bonds after burning of PS. Bulk analyses using ATR-FTIR show that thermal oxidation decreased the alkene (3040-3000 cm-1) and alkane (3000-2850 cm-1) C-H stretch signals suggesting PS chain …

Waking Up The Snake: Ancient Wisdom For Regeneration, Anne Poelina, Bill Webb, Sandra Wooltorton, Naomi Joy Godden

Research outputs 2022 to 2026

The Anthropocene exposes the colonial paradox: ‘that Indigenous people were right all along, that landscapes are neither inert nor mute, but imbued with vitality’ (Ghosh, 2021, p 256). Now, humans must speak out to represent the vital living earth, to return persons of all species to cultures, stories and places. This is called ‘Waking up the Snake’ – using the ancient wisdom of our places to awaken the consciousness of the people to their obligations of stewardship through an ethic of care and love. Serpent goes by many names, being integral to Australia’s Earth Dream, a 65,000-year-old story of sentient …

Advocate Christ Medical Center Year-In-Review Report, 2001, Advocate Health - Midwest

Historical Documents - Combined

Advocate Christ Hospital and Medical Center, Oak Lawn, IL: Annual report for the year 2001. Includes data, statistics, news, and development plans.

Caring, 1989 Fall, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Caring", a semiannual patient education publication. This issue has feature stories on the cardiology department, a cardiac patient story, and tips for living heart healthy.

Caring, 1997 Fall, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Caring", a semiannual patient education publication. This issue introduces a new redesign of the magazine and features articles on asthma in children, and on a new Emergency Room Crisis Intervention Program.

Caring, 1998 Winter, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Caring", a semiannual patient education publication. This issue features services for IMMC's elderly patients, including home health care and the Warren Barr Adult Day Care Program.

Caring, 1987 Summer, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Caring", a semiannual patient education publication. This issue has feature stories on interventional radiology, a pediatric nurse fostering two patients from Central America, and a profile of trustee Rev. Dr. Harold Blake.

Vol. 8 No. 2, Glen Goodknight

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Vol. 8 No. 1, Glen Goodknight

Mythprint

Mythprint is the monthly bulletin of the Mythopoeic Society, a nonprofit educational organization devoted to the study, discussion, and enjoyment of myth and fantasy literature, especially the works of J.R.R. Tolkien, C.S. Lewis, and Charles Williams. To promote these interests, the Society publishes three magazines, maintains a World Wide Web site, and sponsors the annual Mythopoeic Conference and awards for fiction and scholarship, as well as local and written discussion groups.

Economics - The Neglected Dimension Of Pasture Disease R&D, N D. Macleod

IGC Proceedings (1977-2023)

Pasture utilisation underpins a significant contribution of livestock industries to Australia’s economic well-being. Pasture disease represents a direct threat to these enterprises but the economic magnitude of this threat remains largely unknown as the contribution of agricultural economics to pasture disease R&D, management and policy making has been minimal to date. Some insights to explain this apparent neglect are highlighted and a suggestion is made for a multiple disciplinary approach to R&D.

The Effect Of Grazing On Etiolated Regrowth In Eight Grass Species, H A. Lardner, S.B M. Wright, R.D H. Cohen

IGC Proceedings (1977-2023)

Grazing by herbivores affects grass species both morphologically and physiologically. A grazing study was conducted on an irrigated pasture near Outlook, Saskatchewan, Canada during the summers of 1991 and 1992 to determine etiolated regrowth after grazing of reed canarygrass (Phalaris arundinacea L.), slender wheatgrass (Elymus trachycaulus (Link) Gould ex Shinners subsp. trachycaulus), intermediate wheatgrass (Thinopyrum intermedium (Host) Barkw. & D.R. Dewey subsp. intermedium), orchardgrass (Dactylis glomerata L.), meadow bromegrass (Bromus beibersteinii Roem. & Schult.), smooth bromegrass (Bromus inermis Leyss.), tall fescue (Festuca arundinacea (Schreb.) Wimm.) and timothy (Phleum pratense L.) in …

Forage And Animal Management Systems On Communal Rangelands In Arid And Semi-Arid Regions, Panjab Singh, A N. Ghosh

IGC Proceedings (1977-2023)

Grasslands and savannas, which comprise about 25% of the earth's land surface, are undergoing constant degradation, particularly in ar d and semi-arid regions. The rangeland resource is constantly sinking mainly because of its conversion to crop land, leaving farmer and pastorilist vulnerable to environmental extremes. This Paper presents the existing situation and the herbage and animal Product biomass of these regions. Climate and its impact on the Vegetation are discussed. Prevalent systems of rangeland use by sedentary and nomadic herdsman are considered and the constraints 0 the system are enumerated. Livestock 'rearing has been the most important occupation in these …

Combined Collagen And Chitosan Based Devices For Hemostasis And Wound Healing, Kathy Fang

Defensive Publications Series

Collagen and chitosan based devices have been used separately for both hemostasis and wound healing for decades. We investigated developing devices combining both materials that would be useful for hemostasis or wound healing, or both, especially as wound healing is often considered the first phase of wound healing. In-vitro and in-vivo testing of the combined collagen and chitosan derived devices demonstrated the devices had promising hemostatic and wound healing effectiveness compared to the individual materials alone.

The Intersection Of Interprofessional Education And One Health: A Qualitative Study In Human And Veterinary Medical Institutions, Claire Tucker, Jake Keyel, Amy Blue, Ruthanne Chun, Amara Estrada, Hossein Khalili, Anuja Riles, Rohini Roopnarine, Brian Sick, Sue Vandewoude, Brittany Watson, Lauren Wisnieski, Tracy Webb

College of Humanities and Social Sciences Departmental Research

Interprofessional Education (IPE) and One Health are two common and overlapping frameworks for teaching collaborative practice. IPE is common at human medical institutions, while One Health is more common in graduate and veterinary programs. The connection between IPE and One Health is still being explored both in scholarship and in real-world professional settings. This prospective, qualitative research study examines the intersection of IPE and One Health at institutions that are members of the Clinical and Translational Science Award (CTSA) One Health Alliance (COHA). COHA consists of veterinary schools partnered with medical institutions through the National Institutes of Health CTSA funding …

Species Vary In Within-Species Variability, Jennifer Vonk

Animal Sentience

Owens et al. (2024) add to the growing voices stressing the importance of considering individual differences in animal welfare and conservation. I advocate for an additional emphasis on the importance of between species comparisons of the degree of individual variation in cognition and emotion within species. A better understanding of the factors predicting within-species variability will help conservationists target their efforts. Additionally, I caution against invoking circularity in using “behavioural traits” to predict related behaviours.

The Utah Statesman, July 29, 2024, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Evanescent - Issue 5

Evanescent

Evanescent: A Journal of Literary Medicine is the journal of the Eakins Writing Project, which also sponsors the Drs. Theresa and Charles Yeo Writing Prize. The Eakins Writing Project is supported by the Jefferson Center for Injury Research and Prevention, located in the Department of Surgery of Thomas Jefferson University, Philadelphia.

Contents:

5 - Editorial Statement
6 - A Note On Poetry
7 - Mutually Exclusive Identities by Anonymous
9 - If You Can Read This by Anonymous

The Drs. Theresa and Charles Yeo Writing Prize: Honorable Mention:
11 - Happy T-Day by Brittany MacDonald

13 - Watching (R)evolution. …